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Evidence of Interaction Between POLR2A and CDK2

The interaction score between POLR2A and CDK2 is 242.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between POLR2A and CDK2 = 0.34

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

3.80E-3
Orthology
OrganismPOLR2A OrthologueCDK2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YDL140C 1 YBR160W 0.352
  • CoLocalization

Get References From PubMed

fly P04052 1 P23573 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.119
Domains No domains were used in calculating likelihood of interaction 0.028
Post-translational Modifications

Protein: POLR2A

PTMResidueReference
Phosphorylation 1836 PubMed, HPRD
Phosphorylation 1878 PubMed, HPRD
Phosphorylation 1882 PubMed, HPRD
Phosphorylation 1896 PubMed, HPRD
Phosphorylation 1927 PubMed, HPRD
Phosphorylation 1929 PubMed, HPRD
Phosphorylation 1930 PubMed, HPRD
Phosphorylation 1934 PubMed, HPRD
Phosphoserine 1896 HPRD
Phosphoserine 1934 HPRD
Phosphotyrosine 145 HPRD

Protein: CDK2

PTMResidueReference
Dephosphorylation 14 PubMed, HPRD
Dephosphorylation 15 PubMed, HPRD
Dephosphorylation 160 PubMed, HPRD
Phosphorylation 14 PubMed, HPRD
Phosphorylation 15 PubMed, HPRD
Phosphorylation 160 PubMed, HPRD
Phosphothreonine 14 HPRD
Phosphothreonine 160 PubMed, HPRD
Phosphotyrosine 15 PubMed, HPRD
Localisation

Protein: POLR2A

LocalisationReference
Nucleus HPRD
Nucleoplasm HPRD

Protein: CDK2

LocalisationReference
Nucleus HPRD
Nucleolus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between POLR2A and CDK2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between POLR2A andCDK2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , POLR2A has 803 interactors and CDK2 has 1600 interactors of which there are 646 common interactors.

Common InteractorName of Common InteractorScore for POLR2A-Interactor (?)Score for CDK2-Interactor (?)
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 16.60 0.063
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 10.00 0.038
CDK7 CDK7, MO15: Cell division protein kinase 7 10.00 2.47
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 7.66 7.38
IWS1 IWS1, IWS1L: IWS1 homolog 6.64 0.025
TCEA1 N/A 6.64 0.025
C20orf77 N/A 6.64 0.025
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 6.04 0.129
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 4.59 0.046
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 3.39 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 1.33 0.025
NEDD4 NEDD4: Uncharacterized protein NEDD4 1.33 0.025
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 1.26 0.086
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 1.22 0.086
EXOSC10 EXOSC10, PMSCL, PMSCL2: Exosome component 10 0.593 0.119
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.284 0.344
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.254 0.426
RBM14 RBM14, SIP: RNA-binding protein 14 0.210 0.087
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.210 0.070
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.210 0.070
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.188 0.129
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.188 0.078
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.187 0.137
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.187 0.137
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.171 0.114
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.165 0.028
RBM6 RBM6, DEF3: RNA-binding protein 6 0.155 0.032
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.155 0.070
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.174
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.148 0.025
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.139 0.046
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.139 0.078
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.139 0.078
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.139 0.078
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.139 0.129
TIAL1 TIAL1: Nucleolysin TIAR 0.139 0.078
SSB SSB: Lupus La protein 0.139 0.078
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.139 0.078
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.139 0.063
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.139 0.129
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.139 0.046
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.139 0.078
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.139 0.046
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.127 0.0425
NBN NBN, NBS, NBS1, P95: Nibrin 0.127 0.132
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.127 0.144
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.127 0.070
MATR3 MATR3, KIAA0723: Matrin-3 0.127 0.052
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.127 0.032
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.127 0.052
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.123 0.123
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.114 0.276
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.114 0.078
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.188
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.114 0.046
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.114 0.144
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.114 0.078
MCM3 MCM3: DNA replication licensing factor MCM3 0.114 27.40
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.114 0.063
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.114 0.078
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.114 0.038
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.114 0.069
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.114 0.029
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.114 0.144
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.114 0.029
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.114 0.063
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.114 0.046
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.114 0.515
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.114 0.129
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.114 0.078
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.114 0.029
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.114 0.038
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.113 0.069
XRCC1 XRCC1: DNA-repair protein XRCC1 0.096 0.0425
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.096 0.026
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.096 0.0425
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.090 0.033
UBAP2 N/A 0.087 0.087
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.086 0.029
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.083 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.083 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.083 0.028
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.0818 0.063
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.077 0.260
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.075 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.075 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.075 0.025
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.075 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.075 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.075 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.075 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.075 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.075 0.025
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.075 0.025
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.075 0.025
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.073 5.18
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.070 0.144
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.070 0.0425
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.070 0.087
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.070 0.087
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.070 0.087
ARFGAP1 N/A 0.070 0.155
DNMT1 DNMT1, AIM, DNMT: DNA 0.070 0.087
RBM7 0.069 0.046
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.069 0.046
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.067 0.129
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.063 0.046
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.063 0.063
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.063 0.046
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.063 0.063
MTA1 MTA1: Metastasis-associated protein MTA1 0.063 0.063
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.038
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.063 0.046
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.063 0.078
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.063 0.038
TCOF1 N/A 0.052 0.087
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.052 0.087
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.052 0.096
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.052 0.052
ABCF1 N/A 0.052 0.087
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.052 0.087
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.052 0.515
TRRAP N/A 0.052 0.052
COIL COIL, CLN80: Coilin 0.052 0.032
GTF3C1 N/A 0.052 0.026
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.052 0.852
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.052 0.430
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.052 0.052
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.052 0.087
RB1 RB1: Retinoblastoma-associated protein 0.052 0.210
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.087
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.046 0.029
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.046 0.129
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.046 0.078
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.046 0.046
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.046 0.078
GSK3B N/A 0.046 0.038
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.046 0.129
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.046 0.086
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.046 0.078
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.046 0.114
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.046 0.078
CBX3 CBX3: Chromobox protein homolog 3 0.046 0.129
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.046 0.046
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.046 0.063
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.046 0.038
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.046 0.063
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.046 0.063
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.046 0.052
UNG N/A 0.046 0.078
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.046 0.038
SYMPK SYMPK, SPK: Symplekin 0.046 0.046
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.046 0.078
RANBP9 RANBP9, RANBPM: Ran-binding protein 9 0.046 0.029
EP300 N/A 0.046 0.038
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.046 0.063
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.046 0.038
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.046 0.029
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.046 0.038
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.046 0.078
MBD3 MBD3: Methyl-CpG-binding domain protein 3 0.046 0.063
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.046 0.046
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.046 0.038
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.046 0.046
YY1 YY1: Transcriptional repressor protein YY1 0.046 0.063
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.046 0.046
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.046 0.139
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.046 0.046
WBSCR20A N/A 0.046 0.046
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.046 0.046
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.046 0.139
KLHDC4 N/A 0.046 0.038
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.046 0.078
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.038
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.046 0.139
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.046 0.078
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.046 0.129
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.046 0.188
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.046 6.86
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.046 0.038
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.046 0.188
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.046 0.046
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.046 0.078
SAPS3 N/A 0.046 0.038
NOL1 N/A 0.046 0.078
LIG1 LIG1: DNA ligase 1 0.046 0.129
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.046 0.029
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.044 0.025
WDR1 N/A 0.0425 0.0425
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.0425 0.917
H1FX H1FX: Histone H1x 0.0425 0.096
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.0425 0.052
ROCK1 ROCK1: Rho-associated protein kinase 1 0.0425 0.251
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0425 0.070
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.0425 0.0425
GRLF1 N/A 0.0425 0.062
IRF3 IRF3: Interferon regulatory factor 3 0.0425 0.032
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.0425 0.0425
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0425 0.077
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.0425 0.026
API5 N/A 0.0425 0.070
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.0425 0.0425
ESPL1 N/A 0.0425 0.144
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.0425 0.0425
PTMA N/A 0.0425 0.163
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.0425 0.052
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.0425 0.0425
SMARCC2 N/A 0.0425 0.032
GTF2F2 N/A 0.0425 0.0425
GNB2L1 Lung cancer oncogene 7 0.0425 0.070
TOP2B N/A 0.0425 0.052
SREBF2 N/A 0.0425 0.052
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.0425 0.0425
KIAA0853 N/A 0.0425 0.070
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.0425 0.144
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.0425 0.087
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.0425 0.087
EMD EMD, EDMD, STA: Emerin 0.0425 0.0425
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.0425 0.0425
SET SET: Protein SET 0.0425 0.087
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.0425 0.096
ELF1 ELF1: ETS-related transcription factor Elf-1 0.0425 0.127
NFATC1 N/A 0.0425 0.096
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0425 0.0425
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.0425 0.032
HIVEP1 N/A 0.0425 0.032
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.0425 0.052
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.0425 0.210
DDX21 DDX21: Nucleolar RNA helicase 2 0.0425 0.087
PRKAA1 N/A 0.0425 0.026
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.038 0.078
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.038 0.046
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.038 0.078
TP53 TP53, P53: Cellular tumor antigen p53 0.038 0.078
PCNA PCNA: Proliferating cell nuclear antigen 0.038 0.276
HDAC2 HDAC2: Histone deacetylase 2 0.038 0.078
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.038 0.129
NUP153 N/A 0.038 0.129
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.038 0.029
TIMELESS TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog 0.038 0.129
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.078
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.038 0.046
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.038 0.038
PHF10 N/A 0.038 0.063
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.038 0.029
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.038 0.114
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.038 0.225
PPP1R8 N/A 0.038 0.118
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.038 0.038
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.038 0.029
ARMET ARMET, ARP: Protein ARMET precursor 0.038 0.046
CUL4B N/A 0.038 0.029
KIF11 N/A 0.038 0.276
FKBP4 FKBP4: FK506-binding protein 4 0.038 0.046
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.038 0.038
AIP AIP, XAP2: AH receptor-interacting protein 0.038 0.029
TOP3A TOP3A, TOP3: DNA topoisomerase 3-alpha 0.038 0.046
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.038 0.129
COPB2 COPB2: Coatomer subunit beta' 0.038 0.063
H2AFX H2AFX, H2AX: Histone H2A.x 0.038 0.129
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.038 0.029
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.038 0.046
COPE COPE: Coatomer subunit epsilon 0.038 0.038
POLA2 POLA2: DNA polymerase subunit alpha B 0.038 0.129
DIAPH1 Diaphanous 1 0.038 2.02
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.038 0.225
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.038 0.046
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.038 0.063
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.038 0.225
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.038 0.029
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.038 0.035
SOS1 SOS1: Son of sevenless homolog 1 0.038 0.171
CDC20 CDC20: Cell division cycle protein 20 homolog 0.038 0.385
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.038 0.078
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.038 4.15
FZR1 N/A 0.038 2.02
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.038 0.139
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.038 0.078
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.038 0.129
NPM1 NPM1, NPM: Nucleophosmin 0.038 0.385
CDK4 CDK4: Cell division protein kinase 4 0.038 0.276
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.038 0.129
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.038 0.275
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.038 0.188
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.038 0.038
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.038 6.86
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.038 0.127
MDN1 MDN1, KIAA0301: Midasin 0.038 0.046
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.038 6.86
HDAC3 HDAC3: Histone deacetylase 3 0.038 0.078
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.038 0.139
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.038 0.029
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.038 0.029
WDR79 N/A 0.038 0.063
ETS1 ETS1, EWSR2: Protein C-ets-1 0.038 0.069
CSDA CSDA, DBPA: DNA-binding protein A 0.038 0.038
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.038 0.038
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.038 0.029
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.038 0.118
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.038 0.129
RELA RELA, NFKB3: Transcription factor p65 0.038 0.114
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.038 0.129
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.038 0.129
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.038 0.063
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.038 0.046
KIAA1012 KIAA1012: Protein TRS85 homolog 0.038 0.029
MTF1 MTF1: Metal regulatory transcription factor 1 0.038 0.029
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.038 0.056
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.038 0.078
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.038 0.029
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.038 0.078
WEE1 WEE1: Wee1-like protein kinase 0.038 0.129
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.038 0.038
CCNB1 Cyclin B1 0.038 21.70
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.038 0.038
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.038 0.063
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.038 0.029
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.038 0.129
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.038 0.071
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.063
SP3 SP3: Transcription factor Sp3 0.038 0.038
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.038 0.129
USP8 USP8, KIAA0055, UBPY: Ubiquitin carboxyl-terminal hydrolase 8 0.036 0.028
PER2 PER2, KIAA0347: Period circadian protein homolog 2 0.032 0.026
ZNF267 ZNF267: Zinc finger protein 267 0.032 0.032
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.032 0.032
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.026
PLEK PLEK, P47: Pleckstrin 0.032 0.251
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.032 0.032
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.032 0.026
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.052
CENPA CENPA: Histone H3-like centromeric protein A 0.032 0.308
TGIF2 TGIF2: Homeobox protein TGIF2 0.032 0.052
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.032 0.026
IFI16 N/A 0.032 0.0425
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.0971
CHUK N/A 0.032 0.052
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.032 0.0425
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.032 0.152
MKI67 MKI67: Antigen KI-67 0.032 0.575
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.032 0.032
STAT2 STAT2: Signal transducer and activator of transcription 2 0.032 0.191
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.032 0.152
KIF23 N/A 0.032 0.087
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.032 0.152
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.032 0.0425
STK16 N/A 0.032 0.0425
GTF3C4 GTF3C4: General transcription factor 3C polypeptide 4 0.032 0.026
NCOA3 N/A 0.032 0.0425
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.032 0.052
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.032 0.026
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.032 0.026
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.032 0.026
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.032 0.063
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.032 0.038
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.032 0.063
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.032 0.063
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.029 0.049
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.029 0.129
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.038
CXorf9 N/A 0.029 0.114
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.029 0.078
JUNB JUNB: Transcription factor jun-B 0.029 0.056
CUL5 CUL5, VACM1: Cullin-5 0.029 0.038
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.029 0.110
CDK6 CDK6: Cell division protein kinase 6 0.029 0.029
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.029 0.056
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.029 0.029
HDAC6 HDAC6, JM21: Histone deacetylase 6 0.029 0.029
MAFG MAFG: Transcription factor MafG 0.029 0.071
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.029 0.275
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.029 0.824
RCP9 CRCP: DNA-directed RNA polymerase III subunit RPC9 0.029 0.038
SEC31L1 N/A 0.029 0.046
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.029 0.086
CCNH CCNH: Cyclin-H 0.029 0.225
COPA COPA: Coatomer subunit alpha 0.029 0.038
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.029
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.029 0.029
METTL1 METTL1, C12orf1: tRNA 0.029 0.038
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.029 0.136
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.029 6.80
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.029 0.029
MYBL2 MYBL2, BMYB: Myb-related protein B 0.029 0.129
JUND JUND: Transcription factor jun-D 0.029 0.069
FNBP1 N/A 0.029 0.114
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.029 0.029
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.029 0.171
ATM ATM: Serine-protein kinase ATM 0.029 0.069
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.029 0.029
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.029 0.038
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.029 0.049
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.029 0.029
DOK1 DOK1: Docking protein 1 0.029 0.171
PI4KII PI4K2A: Phosphatidylinositol 4-kinase type 2-alpha 0.029 0.029
ZNF335 ZNF335: Zinc finger protein 335 0.029 0.032
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.029 0.136
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.029 0.129
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.029 0.038
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.029 0.069
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.029 0.046
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.029 0.029
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.029 0.046
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.029 0.029
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.029 0.110
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.029 0.029
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.029 0.038
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.029 0.029
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.029 0.038
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.029 0.171
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.029 0.026
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.029 0.129
TCEB3 TCEB3, MSTP059: Transcription elongation factor B polypeptide 3 0.029 0.038
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.029 0.063
CRSP2 MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol 0.029 0.046
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.029 0.038
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.029 0.029
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.029 0.114
SRF SRF: Serum response factor 0.029 0.063
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.029 0.275
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.029 0.069
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.029 0.029
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.029 0.241
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.029 0.129
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.029 0.046
RPS6KB1 N/A 0.029 0.046
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.029
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.029 0.087
RUNX1 N/A 0.029 0.046
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.029 0.063
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.052
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.028
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.028 0.083
NF2 NF2, SCH: Merlin 0.028 0.165
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.028 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.028
BID BID: BH3-interacting domain death agonist 0.028 0.083
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.028 0.083
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.028 0.028
PPEF1 N/A 0.028 0.028
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
ZNF265 N/A 0.028 0.028
RAB4A N/A 0.028 0.052
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.028
CORO6 N/A 0.028 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.028 0.083
SNRPB N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.165
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.028
MAPK15 N/A 0.028 0.083
PHLDB2 N/A 0.028 0.028
IRF7 N/A 0.028 0.028
HES6 HES6: Transcription cofactor HES-6 0.028 0.028
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.028 0.028
UHRF1 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
ZNF579 ZNF579: Zinc finger protein 579 0.028 0.028
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.028 0.028
C20orf18 N/A 0.028 0.028
KIF1B N/A 0.028 0.028
C13orf8 N/A 0.028 0.028
HDAC8 N/A 0.028 0.028
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.028 0.028
DUSP15 N/A 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.028 0.028
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.028 0.083
SYTL4 Endocrine transmitter regulatory protein 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
MAPKAPK5 N/A 0.028 0.028
CABLES1 N/A 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
WDR54 N/A 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.027 0.052
YWHAQ YWHAQ: 14-3-3 protein theta 0.027 0.052
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.027 0.070
SP100 N/A 0.026 0.0425
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.026 0.026
RGS14 N/A 0.026 0.026
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.026 0.0425
MYB MYB: Myb proto-oncogene protein 0.026 0.210
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.026 0.032
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.026 0.026
BACH1 BACH1: Transcription regulator protein BACH1 0.026 0.062
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.026 0.077
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.026 0.127
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.026 0.048
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.026 0.026
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.026 0.026
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.026 0.052
IRS2 IRS2: Insulin receptor substrate 2 0.026 0.109
TSPYL2 TSPYL2, CDA1, HRIHFB2216, DENTT, TSPX: Testis-specific Y-encoded-like protein 2 0.026 0.056
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.032
XRCC4 N/A 0.026 0.032
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.026 0.127
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.026 0.026
AFF1 N/A 0.026 0.070
FLJ23436 N/A 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
CAMK2A N/A 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 4.22
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.025 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 3.97
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
TFAP4 TFAP4: Transcription factor AP-4 0.025 0.028
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.075
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
SEC13L1 N/A 0.025 0.025
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.025 0.028
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.025 0.148
BCOR N/A 0.025 0.025
DIDO1 N/A 0.025 0.025
CAMKK1 N/A 0.025 1.33
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.025
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.025
RNF20 0.025 0.025
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.025
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 7.88
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.025
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.025 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.075
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.025 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.075
MAP2K3 N/A 0.025 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
ELMO1 N/A 0.025 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.025 0.148
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.025 0.148
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
GIT2 N/A 0.025 0.075
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.148
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.025
RBL1 RBL1: Retinoblastoma-like protein 1 0.025 0.075
CCNT2 CCNT2: Cyclin-T2 0.025 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
ATXN2L N/A 0.025 0.025
SOX8 SOX8: Transcription factor SOX-8 0.025 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 7.88
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.025
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 1.33
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.025
PRKCB1 N/A 0.025 0.714
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.047
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.025
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.075
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.025 0.025
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.025 0.025
CREB1 CREB1: cAMP response element-binding protein 0.025 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.025 0.028
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.025 0.025
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.025 0.025
SON 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.025
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.025
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.025 0.025
NIPBL N/A 0.025 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.025 0.047
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.025
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.025 0.075
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
KCTD1 0.025 0.025
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.025 0.025
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.028
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.025 0.025
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.025 0.028
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.025
HDAC7A N/A 0.025 0.028
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.025
GRK6 N/A 0.025 0.025
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
MAX MAX: Protein max 0.025 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.025
EEF2K EEF2K: Elongation factor 2 kinase 0.025 0.165
BRD4 N/A 0.025 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.025 0.028
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.025 0.148
NUP98 N/A 0.025 0.025
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.025 0.025
HTATIP N/A 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.025 0.148
NES N/A 0.025 0.025
0.299
Total Score 242.00