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Evidence of Interaction Between APS and JAK2

The interaction score between APS and JAK2 is 200.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between APS and JAK2 = 0.09

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

1.85E-3
Orthology
OrganismAPS OrthologueJAK2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00016441 0.073 IPI00022353 0.245
human IPI00016441 0.073 IPI00219418 0.385
human IPI00016441 0.073 IPI00011633 0.316
fly Q9U8B9 0.073 Q24592 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.22E-3
Domains Domains present in APS and JAK2:
Domains in APSDomains in JAK2
IPR001849 Pleckstrin-like
IPR000980 SH2 motif
IPR011993 PH_type.
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR000299 Band 4.1
IPR000980 SH2 motif
IPR009127 Janus kinase, JAK
IPR009129 Janus kinase 2, JAK2

The Chi square scores for co-occurrence of domains that are present in APS and JAK2 are listed below.

Domain 1Domain 2Chi Square
IPR000980 SH2 motif IPR008266 Tyrosine protein kinase, active site 383.26
IPR000980 SH2 motif IPR001245 Tyrosine protein kinase 238.73
IPR001849 Pleckstrin-like IPR001245 Tyrosine protein kinase 125.014
IPR001849 Pleckstrin-like IPR008266 Tyrosine protein kinase, active site 119.16
IPR011993 PH_type. IPR001245 Tyrosine protein kinase 88.2896
IPR011993 PH_type. IPR008266 Tyrosine protein kinase, active site 85.0032
IPR000980 SH2 motif IPR000719 Protein kinase 82.1364
IPR001849 Pleckstrin-like IPR000719 Protein kinase 66.4046
IPR000980 SH2 motif IPR011009 Protein kinase-like 59.6059
IPR000980 SH2 motif IPR009127 Janus kinase, JAK 59.5626
IPR001849 Pleckstrin-like IPR000980 SH2 motif 51.2962
IPR000980 SH2 motif IPR000299 Band 4.1 47.6792
IPR001849 Pleckstrin-like IPR011009 Protein kinase-like 42.4143
IPR011993 PH_type. IPR000719 Protein kinase 37.108
IPR000980 SH2 motif IPR000980 SH2 motif 36.445
IPR011993 PH_type. IPR000980 SH2 motif 33.2172
IPR011993 PH_type. IPR011009 Protein kinase-like 21.3114
IPR000980 SH2 motif IPR009129 Janus kinase 2, JAK2 13.3485
IPR011993 PH_type. IPR000299 Band 4.1 6.61795
IPR001849 Pleckstrin-like IPR009127 Janus kinase, JAK 5.84786
IPR001849 Pleckstrin-like IPR000299 Band 4.1 5.83094
IPR011993 PH_type. IPR009127 Janus kinase, JAK 1.5416
IPR001849 Pleckstrin-like IPR009129 Janus kinase 2, JAK2 0.086975
IPR011993 PH_type. IPR009129 Janus kinase 2, JAK2 0.0707049

The background colour of the table refers to:

  • Blue Domain is only present in APS
  • Yellow Domain is only present in JAK2
  • Green Domain is present in both APS and JAK2

1.30
Post-translational Modifications

Protein: APS

PTMResidueReference
Phosphorylation 598 PubMed, HPRD
Phosphotyrosine 629 HPRD

Protein: JAK2

PTMResidueReference
Dephosphorylation 1007 PubMed, HPRD
Dephosphorylation 1008 PubMed, HPRD
Phosphorylation 201 PubMed, HPRD
Phosphorylation 221 PubMed, HPRD
Phosphorylation 570 PubMed, HPRD
Phosphorylation 813 PubMed, HPRD
Phosphorylation 1007 PubMed, HPRD
Phosphorylation 1008 PubMed, HPRD
Localisation

Protein: APS

LocalisationReference
Plasma membrane HPRD
Cytoplasm HPRD

Protein: JAK2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between APS and JAK2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between APS andJAK2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , APS has 1316 interactors and JAK2 has 1724 interactors of which there are 1101 common interactors.

Common InteractorName of Common InteractorScore for APS-Interactor (?)Score for JAK2-Interactor (?)
CSK CSK: Tyrosine-protein kinase CSK 2.94 2.94
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 2.17 3.64
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 1.78 6.03
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 1.78 370.00
LYN LYN: Tyrosine-protein kinase Lyn 1.50 6.73
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 1.50 1.50
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 1.50 0.859
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 1.35 6.03
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 1.30 1.30
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 1.30 1.30
INSL3 JAK3: Tyrosine-protein kinase JAK3 1.20 0.872
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 1.17 1.17
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 1.17 563.00
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 1.17 1.17
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 1.13 0.654
SYK SYK: Tyrosine-protein kinase SYK 1.07 6.03
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.980 0.980
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.980 0.980
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.980 0.980
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.975 0.975
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.975 1.20
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.975 0.859
BMX N/A 0.975 0.859
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.902 1.48
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.878 0.878
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.878 0.878
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.878 0.878
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.878 0.878
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.874 0.770
HCK N/A 0.874 6.03
JAK1 0.874 2.94
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.872 0.775
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.808 0.520
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.808 0.586
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.808 0.586
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.808 0.577
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.770 1.07
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.770 1.35
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.770 333.00
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.770 650.00
MET MET: Hepatocyte growth factor receptor precursor 0.731 0.519
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.655 0.577
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.655 0.577
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.655 0.586
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.655 0.586
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.655 0.586
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.655 0.520
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.655 0.586
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.655 1.06E3
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.617 0.617
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.617 0.617
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.617 0.617
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.617 0.617
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.586 250.00
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.581 0.654
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.581 0.581
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.577 0.520
INSR INSR: Insulin receptor precursor 0.577 277.00
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.577 0.577
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.577 0.655
KIT KIT: Mast/stem cell growth factor receptor precursor 0.577 0.808
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.561 0.081
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.561 0.081
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.553 0.553
FLT4 VEGFR3 long form 0.553 0.553
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.520 0.520
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.515 0.416
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.484 0.484
ALK ALK: ALK tyrosine kinase receptor precursor 0.445 0.361
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.416 0.251
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.307 0.191
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.307 0.515
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.284 0.348
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.275 0.136
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.275 0.088
EEF2 EEF2, EF2: Elongation factor 2 0.275 0.038
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.274 0.072
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.274 0.100
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.274 0.065
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
ROCK1 ROCK1: Rho-associated protein kinase 1 0.251 0.416
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.251 1.98
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.251 0.251
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.251 0.055
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.251 0.109
RET urf-ret: Urf-ret protein 0.251 0.145
TNK1 TNK1: Non-receptor tyrosine-protein kinase TNK1 0.237 0.237
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.225 0.372
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.225 0.088
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.225 0.136
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.225 0.461
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.225 0.225
WASPIP N/A 0.225 0.372
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.225 0.461
CXorf9 N/A 0.225 0.372
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.225 0.225
FNBP1 N/A 0.225 0.275
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.225 0.275
FGFR2 N/A 0.217 0.217
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.202 0.081
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.202 0.100
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.202 0.274
RYK RYK, JTK5A: Tyrosine-protein kinase RYK precursor 0.200 0.162
AMHR2 AMHR2, AMHR: Anti-Muellerian hormone type-2 receptor precursor 0.200 0.129
FYN N/A 0.197 0.491
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.195 0.195
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.191 0.152
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.191 0.123
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.191 1.50
GAB1 GAB1: GRB2-associated-binding protein 1 0.191 0.191
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.191 0.416
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.191 0.416
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.191 0.110
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.191 0.307
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.191 0.307
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.191 0.123
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.181 0.113
INSRR INSRR, IRR: Insulin receptor-related protein precursor 0.179 0.115
LTK LTK, TYK1: Leukocyte tyrosine kinase receptor precursor 0.179 0.296
MUSK MUSK: Muscle, skeletal receptor tyrosine protein kinase precursor 0.179 0.130
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.177 0.274
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.174 0.305
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.171 0.099
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.136
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.171 0.171
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.171 0.078
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.171 0.372
CD2AP CD2AP: CD2-associated protein 0.171 0.275
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.171 0.171
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.171 0.136
PLD1 PLD1: Phospholipase D1 0.171 0.097
VIL2 N/A 0.171 0.136
NCK2 NCK2: Cytoplasmic protein NCK2 0.171 1.35
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.171 0.171
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.171 0.099
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.171 0.372
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.171 0.275
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.171 0.763
VAV1 VAV1, VAV: Proto-oncogene vav 0.171 3.64
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.171 0.171
TLN1 TLN1: Uncharacterized protein TLN1 0.171 0.275
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.171 0.763
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.171 0.763
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.171 0.171
STAT6 STAT6: Signal transducer and activator of transcription 6 0.171 2.90E3
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.171 0.097
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.171 0.275
WEE1 WEE1: Wee1-like protein kinase 0.171 0.110
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.171 0.275
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.166 0.274
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.166 0.202
PLEK PLEK, P47: Pleckstrin 0.166 0.340
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.166 0.274
PSCD2 N/A 0.165 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.165 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.165 0.165
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 1.30
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.165
CNN2 CNN2: Calponin-2 0.165 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.165 0.165
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.165 0.165
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.165
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.165 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.165 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 1.30
NF2 NF2, SCH: Merlin 0.165 0.165
MAPK15 N/A 0.165 0.165
STAT3 0.165 1.30
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.165 0.165
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.165 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.165 0.165
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.165 0.165
EEF2K EEF2K: Elongation factor 2 kinase 0.165 0.165
MAP2K5 N/A 0.165 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.165 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.165
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.165 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.165 0.165
CDC2 CDC2: Cell division control protein 2 homolog 0.165 0.165
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 1.30
MAPKAPK5 N/A 0.165 0.165
STYK1 STYK1, NOK: Tyrosine protein-kinase STYK1 0.162 0.162
MCF2 MCF2, DBL: Proto-oncogene DBL 0.152 0.098
STK16 N/A 0.152 0.152
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.152 0.515
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.152 0.109
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.152 0.109
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.152 0.109
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.152 4.07
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.152 0.109
VASP VASP: Vasodilator-stimulated phosphoprotein 0.152 0.416
DAPK2 DAPK2: Death-associated protein kinase 2 0.152 0.123
GRLF1 N/A 0.152 0.098
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.152 0.152
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.148 0.181
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.148 0.073
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.148 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.148 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.148 0.148
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.148 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.148
ELMO1 N/A 0.148 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.148 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.148
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.148 0.148
RAB5B RAB5B: Ras-related protein Rab-5B 0.148 0.025
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 1.17
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.148
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.148 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.148
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.148 0.148
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 1.17
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.148 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.148 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.148 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.148 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.148 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.148 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.148 0.148
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.148 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.148 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.148 0.025
ARHGEF7 N/A 0.148 0.148
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.148 0.025
TYRO3 TYRO3, BYK, DTK, RSE, SKY: Tyrosine-protein kinase receptor TYRO3 precursor 0.143 0.145
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.143 0.143
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.139 0.372
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.136 0.225
PLD2 PLD2: Phospholipase D2 0.136 0.136
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.136 0.097
CDK7 CDK7, MO15: Cell division protein kinase 7 0.136 0.136
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.136 0.078
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.136 0.171
STK10 STK10: Uncharacterized protein STK10 0.136 0.461
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.136 0.763
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.136 0.461
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.136 0.136
CDK4 CDK4: Cell division protein kinase 4 0.136 0.136
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.136 0.136
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.136 0.372
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.136 0.461
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.136 0.099
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.136 53.10
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.136 0.136
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.136 0.136
DOK1 DOK1: Docking protein 1 0.136 0.461
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.136 0.372
PSCD4 PSCD4, CYT4: Cytohesin-4 0.136 0.763
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.136 0.372
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.136 2.17
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.136 0.099
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.136 0.088
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.136 0.063
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.136 0.099
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.136 0.110
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.136 0.461
RPS6KB1 N/A 0.136 0.372
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.136 0.097
CDK2 CDK2: Cell division protein kinase 2 0.136 0.136
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.136 0.372
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.136 0.275
CRKL CRKL: Crk-like protein 0.136 1.78
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.136 0.097
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.136 0.046
CDK5 CDK5: Cell division protein kinase 5 0.136 0.136
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.136 0.275
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.128 0.128
ROR2 ROR2, NTRKR2: Tyrosine-protein kinase transmembrane receptor ROR2 precursor 0.128 0.130
IPO7 IPO7: Uncharacterized protein IPO7 0.127 0.032
CRLF3 N/A 0.126 0.340
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.126 0.340
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.126 0.340
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.126 0.166
IL9R IL9R: Interleukin-9 receptor precursor 0.126 0.081
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.126 0.340
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.126 0.166
STAT2 STAT2: Signal transducer and activator of transcription 2 0.126 1.48
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.126 0.065
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.126 0.340
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.126 0.072
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.123 0.307
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.123 0.975
CDKL5 N/A 0.123 0.109
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.123 0.852
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.123 0.152
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.123 0.975
LIMK2 LIMK2: LIM domain kinase 2 0.123 0.152
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.123 0.191
COBL N/A 0.123 0.110
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.123
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.123 0.251
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.123 3.28
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.123 0.191
IRS1 IRS1: Insulin receptor substrate 1 0.123 0.109
SPTAN1 N/A 0.123 0.110
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.123 0.087
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.123 0.515
GAB2 N/A 0.123 0.416
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.114 0.275
MDN1 MDN1, KIAA0301: Midasin 0.114 0.086
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.113 0.181
ITGB7 ITGB7: Integrin beta-7 precursor 0.113 0.148
TTN N/A 0.110 0.097
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.110 0.097
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.110 0.097
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.110 0.461
PSD TYL: TYL protein 0.110 0.097
NRAS NRAS, HRAS1: GTPase NRas precursor 0.110 0.046
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.110 0.372
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.110 0.097
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.110 0.063
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.110 0.461
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.110 0.136
RIN1 RIN1: Ras and Rab interactor 1 0.110 1.07
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.110 0.136
DAB1 DAB1: Disabled homolog 1 0.110 0.097
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.110 0.171
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.110 0.225
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.110 0.110
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.110 0.136
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.110 0.088
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.110 0.225
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.110 0.372
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.110 0.275
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.110 0.136
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.110 0.461
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.110 0.275
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.110 0.171
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.110 0.461
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.110 0.088
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.110 0.136
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.110 0.110
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.110 0.110
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.110 0.099
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.110 0.275
SORBS3 SORBS3, SCAM1: Vinexin 0.110 0.097
STAM2 STAM2: Signal transducing adapter molecule 2 0.110 82.20
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.110 0.171
TLN2 TLN2: Uncharacterized protein TLN2 0.110 0.099
RASA3 RASA3: Ras GTPase-activating protein 3 0.110 0.136
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.110 0.088
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.110 0.171
ATM ATM: Serine-protein kinase ATM 0.110 0.225
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.110 0.171
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.110 0.097
MSN MSN: Moesin 0.110 0.461
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.110 1.04E3
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.110 0.225
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.110 0.461
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.110 0.372
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.110 0.088
MYO3A MYO3A: Myosin IIIA 0.110 0.088
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.110 0.275
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.110 0.099
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.110 0.781
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.109 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.109 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.109 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.109 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.109 0.109
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.109 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.109 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.109 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.109 0.109
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.109 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.109 0.109
KIR3DL1 N/A 0.109 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.109 0.109
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.109 0.049
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.109 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.109 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.109 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.109 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.109 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.109 0.109
FN1 N/A 0.109 0.109
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.109 0.109
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.109 0.123
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.109 0.110
PRKAA1 N/A 0.109 0.152
IRS2 IRS2: Insulin receptor substrate 2 0.109 0.416
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.109 0.110
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.109 0.062
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.109 0.191
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.109 0.307
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.100 0.072
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.100 0.126
GHR GHR: Growth hormone receptor precursor 0.100 0.072
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.100 0.561
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.100 0.072
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.100 0.100
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.100 0.0727
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.100 0.340
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.100 0.072
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.100 0.126
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.100 0.081
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.100 0.274
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.100 0.202
SORL1 SORL1: Sortilin-related receptor precursor 0.100 0.274
PVR PVR, PVS: Poliovirus receptor precursor 0.100 0.0727
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.100 0.100
LILRB1 N/A 0.100 1.19
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.098 0.191
CNN3 CNN3: Calponin-3 0.098 0.088
CTTN CTTN, EMS1: Src substrate cortactin 0.098 0.088
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.098 0.098
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.098 0.098
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.098 0.098
CNTN4 CNTN4: Contactin-4 precursor 0.098 0.098
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.098 0.098
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.098 0.044
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.098 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.098
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.098 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 46.90
ATRN N/A 0.098 0.044
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.098 0.098
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.098 422.00
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.098 0.098
CNTN1 CNTN1: Contactin-1 precursor 0.098 0.098
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.098 0.098
BSG N/A 0.098 0.098
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.097 0.088
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.097
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.097 0.078
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.097 0.171
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.097 1.07
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.097 0.097
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.097 0.097
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.097 0.097
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.097 0.225
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.097 0.044
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.097 0.275
PMP2 PMP2: Myelin P2 protein 0.097 0.044
CDK6 CDK6: Cell division protein kinase 6 0.097 0.171
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.097 0.099
PHB2 PHB2, BAP, REA: Prohibitin-2 0.0971 0.048
FUBP1 N/A 0.096 0.155
ITGAE ITGAE: Integrin alpha-E precursor 0.091 0.124
IRF3 IRF3: Interferon regulatory factor 3 0.091 0.075
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.090 0.064
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.090 0.073
SOS1 SOS1: Son of sevenless homolog 1 0.090 0.148
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.090 0.064
NEO1 NEO1, NGN: Neogenin precursor 0.090 0.046
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.090 0.304
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.090 784.00
DCC DCC: Netrin receptor DCC precursor 0.090 0.073
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.090 0.113
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.090 1.33
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.090 0.058
RDX RDX: Radixin 0.088 0.110
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.088 0.088
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.088 0.088
DYRK3 N/A 0.088 0.110
LCP1 LCP1, PLS2: Plastin-2 0.086 0.461
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.086 0.188
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.086 0.038
XPO1 XPO1, CRM1: Exportin-1 0.086 0.046
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.086 0.078
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.086 0.042
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.083 0.083
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.083 0.165
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.083 0.165
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.083 0.165
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.083 0.083
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.081 0.561
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.081 0.100
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.081 0.340
CCR5 CCR5: CCR5 receptor (Fragment) 0.081 0.202
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.081 0.081
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.081 0.065
TP73 TP73, P73: Tumor protein p73 0.081 0.072
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.081 0.561
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.081 0.340
ETS2 ETS2: Protein C-ets-2 0.081 0.126
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.081 0.0727
GPA33 GPA33: Cell surface A33 antigen precursor 0.081 0.081
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.081 0.065
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.081 0.081
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.081 0.065
PRLR PRLR: Prolactin receptor precursor 0.081 0.065
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.081 0.065
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.080 0.077
HD HD, IT15: Huntingtin 0.080 0.0425
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.080 0.163
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.077 0.087
ARFGAP1 N/A 0.075 0.027
SLC9A1 SLC9A1, APNH1, NHE1: Sodium/hydrogen exchanger 1 0.075 0.0453
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.075 0.057
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.075 0.075
GIT2 N/A 0.075 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.075 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.075
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.075 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.148
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.074 0.177
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.073 0.655
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.073 0.090
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.073 0.503
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.073 0.503
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.073 0.064
PTPRZ1 N/A 0.073 0.058
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.073 0.073
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.073 0.073
STAT4 STAT4: Signal transducer and activator of transcription 4 0.072 0.902
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.072 0.081
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.072 2.46
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.072 0.0727
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.072 0.0727
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.072 0.058
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.072 0.581
CD7 CD7: T-cell antigen CD7 precursor 0.072 0.126
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.072 0.072
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.072 0.100
ITGB4 N/A 0.072 0.065
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.072 0.072
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.072 0.081
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.072 0.065
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.072 0.029
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.072 0.065
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.072 0.081
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.072 0.065
EGF EGF: Pro-epidermal growth factor precursor 0.072 0.072
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.072 0.0727
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.072 0.126
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.072 0.081
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.072 0.100
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.070 0.052
CIITA CIITA, MHC2TA: MHC class II transactivator 0.070 0.0971
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.070 0.087
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.069 0.139
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.069 0.078
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.069 0.114
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.069 0.233
GMIP GMIP: GEM-interacting protein 0.069 0.763
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.069 0.049
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.069 0.188
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.0688 0.0688
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.0688 0.0688
F3 F3: Tissue factor precursor 0.065 0.065
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.065 0.126
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.065 0.072
EPOR EPOR: Erythropoietin receptor precursor 0.065 0.126
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.065 0.100
SCML2 SCML2: Sex comb on midleg-like protein 2 0.065 0.065
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.065 0.065
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.065 0.091
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.064 0.148
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.064 0.058
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.064 0.064
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.064 0.029
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.064 0.058
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.064 0.032
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.064 0.065
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.064 0.064
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.064 0.064
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.064
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.063 0.051
CENTA1 CENTA1: Centaurin-alpha 1 0.063 0.0794
FLNA FLNA, FLN, FLN1: Filamin-A 0.062 0.052
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.062 0.062
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.060 0.039
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.059 0.0955
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.065
TNC TNC, HXB: Tenascin precursor 0.058 0.064
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.057 0.046
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.057 0.041
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.057 0.114
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.057 0.037
GRK7 GRK7, GPRK7: G protein-coupled receptor kinase 7 precursor 0.056 0.056
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.056 0.056
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.056 0.225
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.056 0.139
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.056 0.763
ACTG1 ACTB: Actin, cytoplasmic 1 0.056 0.233
HDLBP HDLBP, HBP, VGL: Vigilin 0.056 0.056
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.0554 0.027
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.054 0.063
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.054 0.069
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.053 0.053
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.052 0.165
YWHAG YWHAG: 14-3-3 protein gamma 0.052 0.028
CASP8 CASP8, MCH5: Caspase-8 precursor 0.052 0.083
S100A16 S100A16, AAG13: Protein S100-A16 0.052 0.165
PPEF1 N/A 0.052 0.165
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.052 0.032
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.052 0.026
TRRAP N/A 0.052 0.026
DAPP1 N/A 0.052 0.087
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
MAPK7 MAPK7, ERK4, ERK5, PRKM7: Mitogen-activated protein kinase 7 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
CDC42EP1 CDC42EP1, BORG5, CEP1, MSE55: Cdc42 effector protein 1 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
IGHM N/A 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.617
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
PRKCD PRKCD: Protein kinase C delta type 0.051 0.051
GSK3B GSK3B: Glycogen synthase kinase-3 beta 0.051 0.051
PTPRA N/A 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.617
NULL Ig lambda chain V-I region EPS 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
NCAM1 N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
MAP4K4 N/A 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
RAPH1 N/A 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
IGHG1 N/A 0.051 0.051
UBAP2L N/A 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
MARK2 N/A 0.051 0.051
IGHG3 N/A 0.051 0.051
ITGB1 ITGB1, FNRB, MDF2, MSK12: Integrin beta-1 precursor 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.617
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
C9orf88 N/A 0.051 0.051
CHUK CHUK, IKKA, TCF16: Inhibitor of nuclear factor kappa-B kinase subunit alpha 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
IGHD N/A 0.051 0.051
MAPK11 MAPK11, PRKM11, SAPK2: Mitogen-activated protein kinase 11 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
IGHA1 N/A 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
GRB10 N/A 0.051 0.617
HLA-A N/A 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
NULL Ig kappa chain V-I region CAR 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.051 0.046
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.051 0.041
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.051 0.111
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.051 0.041
SLC9A3 SLC9A3, NHE3: Sodium/hydrogen exchanger 3 0.051 0.026
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.050
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.050 0.088
RIPK2 RIPK2, CARDIAK, UNQ277/PRO314/PRO34092, RICK, RIP2: Receptor-interacting serine/ 0.050 0.050
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.049 0.049
HES6 HES6: Transcription cofactor HES-6 0.049 0.049
DRD2 DRD2: D(2) dopamine receptor 0.049 0.109
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.049 0.049
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.049
TMPRSS9 N/A 0.049 0.04
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.049 0.275
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.048 0.210
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.048 0.032
CDC42EP3 CDC42EP3, BORG2, CEP3: Cdc42 effector protein 3 0.047 0.160
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.047 0.030
SNX3 N/A 0.047 0.148
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.047 0.148
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.046 0.046
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.046 0.038
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.553
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
TLK2 TLK2: Serine/threonine-protein kinase tousled-like 2 0.046 0.046
IKBKE IKBKE, IKKE, IKKI, KIAA0151: Inhibitor of nuclear factor kappa-B kinase subunit 0.046 0.046
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.046 0.046
SRPK1 SRPK1: Serine/threonine-protein kinase SRPK1 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.553
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
LMO7 N/A 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.046 0.037
DLG2 DLG2: Disks large homolog 2 0.046 0.041
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.046 0.041
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.046 0.041
ATP2B1 N/A 0.0453 0.0453
GRM1 GRM1, GPRC1A, MGLUR1: Metabotropic glutamate receptor 1 precursor 0.0453 0.029
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.0453 0.253
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.0453 0.032
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.0453 0.075
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.0453 0.029
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.0453 0.029
IL8RB IL8RB, CXCR2: High affinity interleukin-8 receptor B 0.0453 0.126
CSPG2 N/A 0.045 0.214
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.045 0.045
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.045 0.045
RASA4 RASA4, CAPRI, GAPL, KIAA0538: Ras GTPase-activating protein 4 0.044 0.060
ADRBK2 ADRBK2, BARK2, GRK3: Beta-adrenergic receptor kinase 2 0.044 0.044
ACTN1 ACTN1: Alpha-actinin-1 0.044 0.110
ATP2A3 ATP2A3: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 0.044 0.049
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.044
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.044 0.098
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.044
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.043 0.078
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.043 0.038
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.0425 0.048
UBAP2 N/A 0.0425 0.026
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.0425 0.026
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.0425 0.0425
TNN TNN: Tenascin-N precursor 0.042 0.042
MT3 MT3: Metallothionein-3 0.0416 0.098
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.0416 0.416
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.041 0.181
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.041 0.041
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.041 0.046
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.041 0.046
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.041 0.041
HES1 HES1, HL, HRY: Transcription factor HES-1 0.041 0.029
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.041 0.304
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.041 0.026
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.041 0.026
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.041 0.040
ARHGEF18 ARHGEF18: ARHGEF18 protein 0.041 0.050
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.041
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.041 0.041
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.041 0.037
YWHAQ YWHAQ: 14-3-3 protein theta 0.039 0.032
SNCB SNCB: Beta-synuclein 0.039 0.098
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.039 0.152
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.039 0.123
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.039 0.515
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.039 0.098
S100A7 S100A7, PSOR1: Protein S100-A7 0.039 0.109
HLA-DRB5 HLA-DRB3: HLA class II histocompatibility antigen, DRB3-1 beta chain precursor 0.039 0.053
HLA-DQA1 HLA-DQA1: HLA class II histocompatibility antigen, DQ(5) alpha chain precursor 0.039 0.032
HLA-DQB1 HLA-DQB, HLA-DRB1: HLA class II histocompatibility antigen, DQ(1) beta chain pre 0.039 0.039
HLA-DRB5 HLA-Dw12: Cell surface glycoprotein 0.039 0.053
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.038 0.265
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.038 0.0338
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.038 0.038
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.038 0.071
CCT8 CCT8: Uncharacterized protein CCT8 0.038 0.029
RPL8 RPL8: 60S ribosomal protein L8 0.038 0.046
SYMPK SYMPK, SPK: Symplekin 0.038 0.029
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.038 0.049
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.038 0.038
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.038 0.063
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.038 0.086
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.029
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.038 0.139
LPXN LPXN, LDLP: Leupaxin 0.038 0.046
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.038 0.029
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.037 0.046
FADD FADD, MORT1: Protein FADD 0.037 0.057
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.037 0.065
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.037 0.032
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.037 0.029
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.037 0.0446
RHO RHO, OPN2: Rhodopsin 0.037 0.033
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.037 0.037
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.037 0.041
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.037 0.041
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.037 0.041
CENTB1 CENTB1, KIAA0050: Centaurin-beta 1 0.036 0.036
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.036 0.036
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.036 0.098
CETN1 CETN1, CEN1, CETN: Centrin-1 0.036 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.036 0.098
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.035 0.136
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.035 0.171
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.035 0.049
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.035 0.461
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.034 0.098
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.034 0.049
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.034 0.251
S100B S100B: Protein S100-B 0.034 0.098
S100A3 S100A3, S100E: Protein S100-A3 0.034 0.098
CNN1 CNN1: Calponin-1 0.0338 0.030
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.0338 0.047
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0338 0.034
MAL2 MAL2: Protein MAL2 0.034 0.034
OPRM1 OPRM1, MOR1: Mu-type opioid receptor 0.034 0.034
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.033 0.044
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.0333 0.087
FABP1 FABP1, FABPL: Fatty acid-binding protein, liver 0.033 0.055
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.033 0.032
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.033 0.029
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.033 0.029
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.033 0.067
TSHR N/A 0.033 0.029
GRM3 GRM3, GPRC1C, MGLUR3: Metabotropic glutamate receptor 3 precursor 0.033 0.026
SLC9A7 SLC9A7, NHE7: Sodium/hydrogen exchanger 7 0.033 0.041
MYH9 MYH9: Myosin-9 0.033 0.0818
DRD1 DRD1: D(1A) dopamine receptor 0.033 0.058
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.033 0.029
SELE SELE, ELAM1: E-selectin precursor 0.032 0.033
CD44 N/A 0.032 0.153
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.032 0.081
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.032 0.065
MPG N/A 0.032 0.0425
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.032 0.0425
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.032 0.032
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.032 0.087
ABCF1 N/A 0.032 0.032
DNM2 N/A 0.032 0.070
CHUK N/A 0.032 0.052
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.032 0.067
CD82 CD82, KAI1, SAR2, ST6, TSPAN27: CD82 antigen 0.032 0.041
HLA-DPA1 HLA-DPA1, HLA-DP1A, HLASB: HLA class II histocompatibility antigen, DP alpha cha 0.032 0.053
APBA3 APBA3, MINT3, X11L2: Amyloid beta A4 precursor protein-binding family A member 3 0.032 0.039
IFNGR2 IFNGT1, IFNGR2: Interferon-gamma receptor beta chain precursor 0.032 0.053
CD83 CD83: CD83 antigen precursor 0.032 0.032
MYL3 MYL3: Myosin light polypeptide 3 0.0308 0.097
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.0308 0.099
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.0308 0.088
CSNK1G3 CSNK1G3: Casein kinase I isoform gamma-3 0.0308 0.050
DYRK2 DYRK2: Dual specificity tyrosine-phosphorylation-regulated kinase 2 0.0308 0.041
NUAK1 NUAK1, ARK5, KIAA0537: NUAK family SNF1-like kinase 1 0.030 0.031
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.116
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.030 0.125
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.030 0.037
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.030 0.030
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.030 0.030
RAB32 RAB32: Ras-related protein Rab-32 0.0296 0.076
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.029 0.202
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 0.029 0.032
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.029 0.041
HPN HPN, TMPRSS1: Serine protease hepsin 0.029 0.029
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.029 0.503
FRG1 FRG1: Protein FRG1 0.029 0.063
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.029 0.038
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.029 0.046
CFL1 CFL1, CFL: Cofilin-1 0.029 0.054
TBCE TBCE: Tubulin-specific chaperone E 0.029 0.054
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.029 0.046
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.029 0.046
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.038
RPS10 RPS10: 40S ribosomal protein S10 0.029 0.046
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.029
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.029 0.046
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.029 0.114
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.029 0.071
KIAA1012 KIAA1012: Protein TRS85 homolog 0.029 0.129
LDHB LDHB: L-lactate dehydrogenase B chain 0.029 0.029
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.029
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.029 0.069
QARS QARS: Glutaminyl-tRNA synthetase 0.029 0.063
STMN1 STMN1, LAP18, OP18: Stathmin 0.029 0.097
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.029 0.046
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.029 0.046
GMFB GMFB: Glia maturation factor beta 0.029 0.035
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.029 0.046
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.029 0.063
SEC24B SEC24B: Protein transport protein Sec24B 0.029 0.118
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.029 0.114
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.029 0.078
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.029 0.038
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.029 0.046
VCP VCP: Transitional endoplasmic reticulum ATPase 0.029 0.038
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.029 0.063
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.029 0.046
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.029 0.114
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.029 0.056
NULL N/A 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
ROS1 ROS1: Proto-oncogene tyrosine-protein kinase ROS precursor 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
TESK2 TESK2: Dual specificity testis-specific protein kinase 2 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
AATK apoptosis-associated tyrosine kinase 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
NULL N/A 0.0288 0.0288
MUSK MUSK: MUSK protein 0.0288 0.0288
NTRK3 N/A 0.0288 0.0288
DDR2 DDR2, NTRKR3, TKT, TYRO10: Discoidin domain-containing receptor 2 precursor 0.0288 0.0288
NULL Tyrosine kinase 0.0288 0.0288
NTRK3 NTRK3, TRKC: NT-3 growth factor receptor precursor 0.0288 0.0288
TTN TTN: Uncharacterized protein TTN (Fragment) 0.0288 0.0288
GAK GAK: Cyclin G-associated kinase 0.029 0.059
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
MATK 0.028 0.028
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.028
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.028 0.028
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.028 0.052
CASP9 CASP9, MCH6: Caspase-9 precursor 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
NCF4 N/A 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.028 0.028
LNX1 N/A 0.028 0.028
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.028 0.083
PKP4 PKP4: Plakophilin-4 0.028 0.028
PTPN7 N/A 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
CACNB2 N/A 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.028
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.028 0.028
CDC42 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
C9orf88 N/A 0.028 0.028
AXIN1 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.028 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.028
PHLDB2 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.028 0.136
CHP CHP: Calcium-binding protein p22 0.028 0.225
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.028 0.372
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.028 0.088
APBB1IP APBB1IP, PREL1, RARP1, RIAM: Amyloid beta A4 precursor protein-binding family B 0.028 0.036
GRAP GRAP: GRB2-related adapter protein 0.028 0.218
CLK3 CLK3: Dual specificity protein kinase CLK3 0.028 0.036
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 0.028 0.044
ABCE1 ABCE1, RLI, OK/SW-cl.40, RNASEL1, RNASELI, RNS4I: ATP-binding cassette sub-famil 0.028 0.036
MTMR1 MTMR1: Myotubularin-related protein 1 0.028 0.044
STK17A STK17A, DRAK1: Serine/threonine-protein kinase 17A 0.028 0.028
WASF2 WASF2, WAVE2: Wiskott-Aldrich syndrome protein family member 2 0.028 0.074
RAD23B RAD23B: UV excision repair protein RAD23 homolog B 0.028 0.036
RP6-213H19.1 MST4, MASK: Serine/threonine-protein kinase MST4 0.028 0.044
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
CAMKK2 CAMKK2, CAMKKB, KIAA0787: Calcium/calmodulin-dependent protein kinase kinase 2 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.265
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
MID2 N/A 0.027 0.027
CADPS CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1 0.027 0.027
RIPK5 RIPK5, KIAA0472, HDCMD38P, RIP5, SGK496: Receptor-interacting serine/threonine-p 0.027 0.027
ANKK1 ANKK1, PKK2, SGK288: Ankyrin repeat and protein kinase domain-containing protein 0.027 0.027
PTPN13 N/A 0.027 0.027
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
TSSK3 TSSK3, SPOGA3, STK22C: Testis-specific serine/threonine-protein kinase 3 0.027 0.027
NEBL N/A 0.027 0.027
ASB2 ASB2: Ankyrin repeat and SOCS box protein 2 0.027 0.027
NEK11 NEK11: Serine/threonine-protein kinase Nek11 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 0.027 0.027
NEK4 NEK4, STK2: Serine/threonine-protein kinase Nek4 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.265
CAMKK1 CAMKK1, CAMKKA: Calcium/calmodulin-dependent protein kinase kinase 1 0.027 0.027
MLCK MYLK3, MLCK: Putative myosin light chain kinase 3 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
ASB3 ASB3: ASB3 protein 0.027 0.027
STAC STAC: SH3 and cysteine-rich domain-containing protein 0.027 0.027
PSD3 N/A 0.027 0.027
PXK PXK: PX domain-containing protein kinase-like protein 0.027 0.027
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
PSKH2 PSKH2: Serine/threonine-protein kinase H2 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
OSBPL9 N/A 0.027 0.027
EFS EFS: Embryonal Fyn-associated substrate 0.027 0.027
PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 0.027 0.027
ALS2CR7 ALS2CR7: Serine/threonine-protein kinase ALS2CR7 0.027 0.027
MALT1 MALT1, MLT: Mucosa-associated lymphoid tissue lymphoma translocation protein 1 0.027 0.027
CADPS2 CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2 0.027 0.027
FANK1 FANK1, HSD13, UNQ6504/PRO21382: Fibronectin type 3 and ankyrin repeat domains pr 0.027 0.027
SORBS2 N/A 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.265
TRIM9 TRIM9, KIAA0282, RNF91: Tripartite motif-containing protein 9 0.027 0.027
CDC2L2 N/A 0.027 0.027
PDIK1L PDIK1L, CLIK1L: Serine/threonine-protein kinase PDIK1L 0.027 0.027
CASKIN1 N/A 0.027 0.027
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
UBL7 UBL7, BMSCUBP, SB132: Ubiquitin-like protein 7 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
DOK6 DOK6: Uncharacterized protein DOK6 0.027 0.027
FAM43A N/A 0.027 0.027
STK35 STK35, CLIK1, PDIK1: Serine/threonine-protein kinase 35 0.027 0.027
SHANK1 SHANK1: SH3 and multiple ankyrin repeat domains protein 1 0.027 0.027
DUSP10 DUSP10, MKP5: Dual specificity protein phosphatase 10 0.027 0.027
ABI3 ABI3, NESH: ABI gene family member 3 0.027 0.027
PPP1R9A PPP1R9A, KIAA1222: Neurabin-1 0.027 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.265
NBN NBN, NBS, NBS1, P95: Nibrin 0.027 0.036
ZNF267 ZNF267: Zinc finger protein 267 0.027 0.027
NCOA3 N/A 0.027 0.036
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.0263 0.074
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.0263 0.027
ANXA9 ANXA9, ANX31: Annexin A9 0.0263 0.0263
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.026 0.137
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.026 0.041
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.026 0.026
FES N/A 0.0258 0.0258
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.026 0.210
RP2 RP2: Protein XRP2 0.026 0.087
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.026 0.070
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.026 0.062
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.026 0.052
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.026 0.077
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.026 0.070
IFI35 N/A 0.026 0.070
MARK2 N/A 0.026 0.070
CASP8 N/A 0.026 0.070
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.026 0.026
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.026 0.070
TK1 TK1: Thymidine kinase, cytosolic 0.026 0.026
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.026 0.060
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.026 0.0425
RYR1 0.025 0.041
CD6 CD6: T-cell differentiation antigen CD6 precursor 0.025 0.031
RYR2 RYR2: Ryanodine receptor 2 0.025 0.045
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
TSC2 TSC2, TSC4: Tuberin 0.025 0.075
EPN2 N/A 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 0.047
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
MAP2K3 N/A 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
SCRIB N/A 0.025 0.025
GRK6 N/A 0.025 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.148
CASP7 N/A 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
BCOR N/A 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.148
CAMK2A N/A 0.025 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.047
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.047
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.047
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
NIPBL N/A 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
CAMKK1 N/A 0.025 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.025 0.075
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
BCR N/A 0.025 0.025
PRKCB1 N/A 0.025 0.025
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.025
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.025
SVIL SVIL: Supervillin 0.025 0.047
RAC1 N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
GSN GSN: Gelsolin precursor 0.025 0.047
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
MYO18A 0.025 0.025
LMO6 LMO6: LIM domain only protein 6 0.025 0.025
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.047
DBNL N/A 0.025 0.025
0.572
Total Score 200.00