PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between COPB2 and COPE

The interaction score between COPB2 and COPE is 26.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between COPB2 and COPE = 0.54

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

6.27E-3

Orthology

Organism	COPB2 Orthologue		COPE Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
worm	Q20168	1	O62246	1
fly	O62621	1	Q9Y0Y5	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.22E-3

Domains

Domains present in COPB2 and COPE:

Domains in COPB2

Domains in COPE

IPR001680	G-protein beta WD-40 repeat
IPR006692	Coatomer WD associated region

IPR008940	Protein prenyltransferase
IPR006822	Coatomer epsilon subunit
IPR011990	TPR-like_helical.

The Chi square scores for co-occurrence of domains that are present in COPB2 and COPE are listed below.

Domain 1		Domain 2		Chi Square
IPR001680	G-protein beta WD-40 repeat	IPR008940	Protein prenyltransferase	21.9481
IPR001680	G-protein beta WD-40 repeat	IPR011990	TPR-like_helical.	2.6268

The background colour of the table refers to:

Blue Domain is only present in COPB2
Yellow Domain is only present in COPE
Green Domain is present in both COPB2 and COPE

0.083

Post-translational Modifications

Protein: COPB2

PTM	Residue	Reference
Acetylation	2	PubMed, HPRD

Protein: COPE

PTM	Residue	Reference
Acetylation	283	PubMed, HPRD

Localisation

Protein: COPB2

Localisation	Reference
Golgi	HPRD
Cytoplasm	HPRD

Protein: COPE

Localisation	Reference
ER	HPRD
Golgi	HPRD
Cytoplasm	HPRD

Transitive Score

The common interactors between COPB2 and COPE that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between COPB2 andCOPE. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , COPB2 has 935 interactors and COPE has 1077 interactors of which there are 729 common interactors.

Common Interactor	Name of Common Interactor	Score for COPB2-Interactor (?)	Score for COPE-Interactor (?)
PPID	PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase	23.80	0.139
CSNK2A1	CSNK2A1: CSNK2A1 protein	20.60	0.078
COPA	COPA: Coatomer subunit alpha	20.60	43.10
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	12.30	0.054
EIF3S4	EIF3S4: Eukaryotic translation initiation factor 3 subunit 4	12.30	0.129
PSMA3	PSMA3, PSC8: Proteasome subunit alpha type-3	10.50	0.063
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	10.50	0.046
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	8.55	0.046
RRM2	RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2	6.31	0.038
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	6.31	0.188
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	3.61	0.027
RAD50	RAD50: DNA repair protein RAD50	3.39	0.025
HSP90AA1	Hsp89-alpha-delta-N	1.71	0.225
OSBP	OSBP, OSBP1: Oxysterol-binding protein 1	1.71	0.046
ME2	ME2: NAD-dependent malic enzyme, mitochondrial precursor	1.71	0.046
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	1.33	0.075
ARF1	ARF1: ADP-ribosylation factor 1	1.10	0.081
RAB5B	RAB5B: Ras-related protein Rab-5B	0.683	0.075
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.461	0.063
H2AFX	H2AFX, H2AX: Histone H2A.x	0.372	0.038
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.372	0.046
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.372	0.129
CENPA	CENPA: Histone H3-like centromeric protein A	0.307	0.0425
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.284	2.08
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.275	0.063
HDAC2	HDAC2: Histone deacetylase 2	0.233	0.046
CUL5	CUL5, VACM1: Cullin-5	0.225	0.114
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.225	0.046
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.225	0.063
NBN	NBN, NBS, NBS1, P95: Nibrin	0.210	0.155
HDAC3	HDAC3: Histone deacetylase 3	0.188	0.046
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.188	0.063
TBCE	TBCE: Tubulin-specific chaperone E	0.181	0.046
SOS1	SOS1: Son of sevenless homolog 1	0.171	0.029
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	0.171	0.038
DDX21	DDX21: Nucleolar RNA helicase 2	0.163	0.052
XRCC1	XRCC1: DNA-repair protein XRCC1	0.155	0.080
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.148	0.025
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.146	0.114
MTA1	MTA1: Metastasis-associated protein MTA1	0.139	0.046
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.139	0.071
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.139	0.063
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.139	0.029
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.139	0.087
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.139	0.046
SMAD3	SMAD3, MADH3: Mothers against decapentaplegic homolog 3	0.139	0.038
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.139	0.046
HIST3H3	HIST3H3, H3FT: Histone H3.1t	0.136	0.029
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.132	0.127
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.132	0.070
RB1	RB1: Retinoblastoma-associated protein	0.132	0.0425
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.132	0.052
SEC31L1	N/A	0.129	0.188
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.127	0.052
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.127	0.077
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.127	0.080
DNMT1	DNMT1, AIM, DNMT: DNA	0.127	0.052
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.118	0.063
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.118	0.063
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.118	0.233
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.118	0.188
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.118	0.046
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.114	0.054
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.114	0.086
JARID1A	JARID1A, RBBP2, RBP2: Histone demethylase JARID1A	0.114	0.046
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.114	0.146
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.114	0.114
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.112	0.372
CDC23	CDC23: Cell division cycle protein 23 homolog	0.112	0.139
XPO1	XPO1, CRM1: Exportin-1	0.111	0.139
G3BP	G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1	0.111	0.038
HIST2H2BE	HIST2H2BE, H2BFQ: Histone H2B type 2-E	0.110	0.029
RSN	CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1	0.098	0.075
DCTN1	DCTN1: Dynactin subunit 1	0.098	0.025
IPO7	IPO7: Uncharacterized protein IPO7	0.091	0.077
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.090	0.275
CKAP1	TBCB, CG22, CKAP1: Tubulin folding cofactor B	0.090	0.046
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.087	0.070
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.087	0.087
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.087	0.070
WDR1	N/A	0.087	0.260
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.087	0.260
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.087	0.063
C20orf4	C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4	0.087	0.139
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.087	0.046
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.087	0.063
KIAA1012	KIAA1012: Protein TRS85 homolog	0.087	0.139
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.087	0.114
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.083	0.028
HES6	HES6: Transcription cofactor HES-6	0.083	0.028
HDAC8	N/A	0.083	0.028
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.080	0.052
IRF3	IRF3: Interferon regulatory factor 3	0.080	0.070
CBX3	CBX3: Chromobox protein homolog 3	0.078	0.046
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.078	0.078
RBM7		0.078	0.038
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.078	0.046
SSB	SSB: Lupus La protein	0.078	0.046
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.078	0.063
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.078	0.046
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.078	0.063
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.078	0.046
YY1	YY1: Transcriptional repressor protein YY1	0.078	0.078
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.046
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.078	0.063
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.078	0.063
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.078	0.078
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.078	0.078
NFE2L2	NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2	0.078	0.038
ARMET	ARMET, ARP: Protein ARMET precursor	0.078	0.063
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.078	0.046
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.078	0.063
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.078	0.046
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.078	0.063
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.078	0.063
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.077	0.048
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.077	0.077
CUL2	CUL2: Cullin-2	0.076	0.027
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.075	0.025
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.075	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.075	0.028
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.075	0.025
HDAC7A	N/A	0.075	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.075	0.025
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.075	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.075	0.025
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.071	0.139
MYBL2	MYBL2, BMYB: Myb-related protein B	0.071	0.029
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.071	0.038
DDX3Y	DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y	0.071	0.038
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.071	0.046
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.071	0.029
ABCF1	N/A	0.070	0.087
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.070	0.052
PTMA	N/A	0.070	0.052
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.070	0.155
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.052
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.070	0.052
CDKN1A	CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi	0.070	0.0425
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.070	0.052
SET	SET: Protein SET	0.070	0.052
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.070	0.052
API5	N/A	0.070	0.032
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.070	0.070
CUL3	CUL3, KIAA0617: Cullin-3	0.070	0.030
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.069	0.114
RGS19	RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19	0.067	0.046
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.067	0.063
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.066	0.063
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.066	0.078
RARS	RARS: Arginyl-tRNA synthetase, cytoplasmic	0.066	0.063
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.066	0.063
MCM3	MCM3: DNA replication licensing factor MCM3	0.063	0.046
POLA2	POLA2: DNA polymerase subunit alpha B	0.063	0.046
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.063	0.046
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.063	0.046
PPP1R8	N/A	0.063	0.188
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.063	0.139
CDK7	CDK7, MO15: Cell division protein kinase 7	0.063	0.046
CCNB1	Cyclin B1	0.063	0.038
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.063	0.139
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.063	0.046
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.063	0.063
CDK4	CDK4: Cell division protein kinase 4	0.063	0.046
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.063	0.046
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.063	0.063
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.063	0.038
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.063	0.233
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.063	0.063
SRF	SRF: Serum response factor	0.063	0.139
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.063	0.046
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.063	0.063
TP53	TP53, P53: Cellular tumor antigen p53	0.063	0.139
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.063	0.063
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.063	0.188
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.063	0.063
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.063	0.063
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.063	0.063
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.063	0.063
NUP153	N/A	0.063	0.046
CDK2	CDK2: Cell division protein kinase 2	0.063	0.038
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.063	0.046
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.063	0.046
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.063	0.139
NPM1	NPM1, NPM: Nucleophosmin	0.063	0.038
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.063	0.046
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.063	0.385
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.063	0.046
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.063	0.046
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.063	0.063
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.063	0.078
GRK1	GRK1, RHOK: Rhodopsin kinase precursor	0.062	0.062
MECP2	MECP2: Methyl-CpG-binding protein 2	0.062	0.026
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.060	0.032
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.060	0.032
RGS2	RGS2, G0S8: Regulator of G-protein signaling 2	0.057	0.0425
RERE	RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei	0.056	0.029
LIG4	LIG4: DNA ligase 4	0.056	0.035
SPAG1	SPAG1: Sperm-associated antigen 1	0.056	0.044
NEDD4L	NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein	0.055	0.062
KIAA0664	KIAA0664: Putative eukaryotic translation initiation factor 3 subunit	0.054	0.114
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.054	0.046
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.054	0.038
FKBP4	FKBP4: FK506-binding protein 4	0.054	0.086
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.054	0.026
TMEM1	TMEM1, EHOC1: Transmembrane protein 1	0.054	0.114
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.054	0.114
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.052	0.028
SAT	SAT1, SAT: Diamine acetyltransferase 1	0.052	0.0425
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.052	0.070
ROCK1	ROCK1: Rho-associated protein kinase 1	0.052	0.127
MATR3	MATR3, KIAA0723: Matrin-3	0.052	0.0425
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.052	0.052
AFF1	N/A	0.052	0.0425
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.052	0.087
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.052	0.0425
ARFGAP1	N/A	0.052	0.070
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.052	0.251
GTF2F2	N/A	0.052	0.032
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.052	0.032
MKI67	MKI67: Antigen KI-67	0.052	0.096
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.052	0.070
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.052	0.080
TOP2B	N/A	0.052	0.0425
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.052	0.052
PLEK	PLEK, P47: Pleckstrin	0.052	0.070
UBAP2	N/A	0.052	0.052
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.052	0.070
TCOF1	N/A	0.052	0.0425
EMD	EMD, EDMD, STA: Emerin	0.052	0.052
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.052	0.0425
KIF23	N/A	0.052	0.032
ELF1	ELF1: ETS-related transcription factor Elf-1	0.052	0.070
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.052	0.087
IFI16	N/A	0.052	0.052
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.052	0.0425
KIAA0853	N/A	0.052	0.0425
RBM14	RBM14, SIP: RNA-binding protein 14	0.052	0.070
CHUK	N/A	0.052	0.032
TGIF2	TGIF2: Homeobox protein TGIF2	0.052	0.052
IFNGR1	IFNGR1: Interferon-gamma receptor alpha chain precursor	0.0513	0.027
TRIP12	TRIP12, KIAA0045: Probable E3 ubiquitin-protein ligase TRIP12	0.049	0.055
RGS18	RGS18, RGS13: Regulator of G-protein signaling 18	0.049	0.028
AXIN1		0.049	0.028
PRKG1	PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme	0.049	0.049
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.048	0.032
MYB	MYB: Myb proto-oncogene protein	0.048	0.026
RBL1	RBL1: Retinoblastoma-like protein 1	0.047	0.025
EEF2K	EEF2K: Elongation factor 2 kinase	0.047	0.075
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.047	0.025
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.047	0.025
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.047	0.025
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.047	0.025
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.046	0.046
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.046	0.038
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.046	0.029
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.046	0.038
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.046	0.038
SSH1	SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1	0.046	0.038
SP3	SP3: Transcription factor Sp3	0.046	0.046
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.046	0.038
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.046	0.046
RREB1	RREB1, FINB: RAS-responsive element-binding protein 1	0.046	0.038
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.046	0.078
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.046	0.046
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.046	0.046
GSK3B	N/A	0.046	0.063
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.046	0.046
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.046	0.063
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.046	0.078
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.046	0.233
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.046	0.046
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.046	0.029
SAPS3	N/A	0.046	0.038
PHF10	N/A	0.046	0.038
SYMPK	SYMPK, SPK: Symplekin	0.046	0.063
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.046	0.038
CDC20	CDC20: Cell division cycle protein 20 homolog	0.046	0.114
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.046	0.038
LIG1	LIG1: DNA ligase 1	0.046	0.038
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.046	0.046
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.046	0.038
GGCX	GGCX, GC: Vitamin K-dependent gamma-carboxylase	0.046	0.038
FZR1	N/A	0.046	0.029
DIAPH1	Diaphanous 1	0.046	0.046
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.046	0.046
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.046	0.188
PCNA	PCNA: Proliferating cell nuclear antigen	0.046	0.038
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.046	0.078
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.046	0.038
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.046	0.029
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.046	0.114
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.046	0.188
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.046	0.038
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.046	0.046
KLHDC4	N/A	0.046	0.046
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.046	0.139
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.046	0.038
KIF11	N/A	0.046	0.029
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.046	0.046
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.046	0.188
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.046	0.038
MTF1	MTF1: Metal regulatory transcription factor 1	0.046	0.0425
MYH9	MYH9: Myosin-9	0.046	0.063
NOL1	N/A	0.046	0.038
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.046	0.063
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.046	0.114
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.046	0.046
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.046	0.046
BCDO2	PTS: 6-pyruvoyl tetrahydrobiopterin synthase	0.046	0.069
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.046	0.038
EP300	N/A	0.046	0.046
RPS6KB1	N/A	0.046	0.114
HGS	HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate	0.046	0.233
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.046	0.188
MAFG	MAFG: Transcription factor MafG	0.046	0.046
CUL4B	N/A	0.046	0.046
UNG	N/A	0.046	0.038
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.046	0.063
RELA	RELA, NFKB3: Transcription factor p65	0.046	0.063
DOK1	DOK1: Docking protein 1	0.046	0.046
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.046	0.038
ITGB7	ITGB7: Integrin beta-7 precursor	0.046	0.067
TGFBR2	TGFBR2: TGF-beta receptor type-2 precursor	0.046	0.033
YWHAQ	YWHAQ: 14-3-3 protein theta	0.0446	0.052
G3BP2	G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2	0.044	0.025
AIP	AIP, XAP2: AH receptor-interacting protein	0.043	0.139
RBL2	RBL2, RB2: Retinoblastoma-like protein 2	0.043	0.029
RXRA	RXRA, NR2B1: Retinoic acid receptor RXR-alpha	0.0425	0.127
SREBF2	N/A	0.0425	0.052
SP100	N/A	0.0425	0.0425
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.0425	0.032
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.0425	0.070
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.0425	0.070
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.0425	0.052
GTF3C1	N/A	0.0425	0.070
ESPL1	N/A	0.0425	0.032
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.0425	0.032
TRRAP	N/A	0.0425	0.052
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.0425	0.032
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.0425	0.032
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.0425	0.0425
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.0425	0.052
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.0425	0.0425
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.0425	0.032
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.0425	0.026
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.0425	0.026
NCOA3	N/A	0.0425	0.052
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.0425	0.052
MAPK7	mitogen-activated protein kinase 7 isoform 1	0.0425	0.070
HIVEP1	N/A	0.0425	0.032
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.0425	0.0425
ERF	ERF: ETS domain-containing transcription factor ERF	0.0425	0.0425
VIM	VIM: Vimentin	0.0425	0.0425
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.0425	0.032
JAK1		0.041	0.038
STUB1	STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1	0.041	0.139
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.041	0.069
RAPGEF6	RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6	0.041	0.029
NASP	NASP: Nuclear autoantigenic sperm protein	0.04	0.083
HDLBP	HDLBP, HBP, VGL: Vigilin	0.040	0.063
CTNNB1	CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1	0.040	0.038
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.040	0.188
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.040	0.763
PSMA5	PSMA5: Proteasome subunit alpha type-5	0.040	0.063
HNRPK	N/A	0.040	0.063
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.040	0.046
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.040	0.078
IL10RA	IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor	0.039	0.027
CSF2RB	CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor	0.039	0.027
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.038	0.046
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.038	0.038
WBSCR20A	N/A	0.038	0.046
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.038	0.046
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.038	0.046
DYNC1I2	N/A	0.038	0.069
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.038	0.046
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.038	0.046
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.038	0.063
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.038	0.029
ARID3A	ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein	0.038	0.038
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.038	0.046
TCEB3	TCEB3, MSTP059: Transcription elongation factor B polypeptide 3	0.038	0.046
DYNC1LI1	DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1	0.038	0.139
CCNH	CCNH: Cyclin-H	0.038	0.038
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.038	0.063
BRD3	BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3	0.038	0.046
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.038	0.029
WDR79	N/A	0.038	0.029
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.038	0.038
WDR44	WDR44: WD repeat-containing protein 44	0.038	0.038
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.038	0.086
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.038	0.038
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.038	0.063
FNBP1	N/A	0.038	0.063
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.038	0.063
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.038	0.029
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.038	0.046
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.038	0.046
ZNF217	ZNF217, ZABC1: Zinc finger protein 217	0.038	0.046
VDR	VDR, NR1I1: Vitamin D3 receptor	0.038	0.069
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.038	0.029
CSDA	CSDA, DBPA: DNA-binding protein A	0.038	0.038
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.038	0.038
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.038	0.046
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.038	0.139
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.038	0.046
FTH1	FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain	0.036	0.070
MPG	N/A	0.036	0.144
RHOA	RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor	0.036	0.260
HSP90AB1	HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta	0.036	0.251
LIMS1	N/A	0.036	0.052
EDD1	EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1	0.035	0.051
ITGB2	ITGB2, CD18, MFI7: Integrin beta-2 precursor	0.035	0.0818
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.032	0.032
RGS14	N/A	0.032	0.0425
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.032	0.062
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.032	0.026
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.032	0.032
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.032	0.0425
H1FX	H1FX: Histone H1x	0.032	0.070
KRT18	KRT18: Uncharacterized protein KRT18	0.032	0.026
ETS2	ETS2: Protein C-ets-2	0.032	0.0425
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.032	0.026
COIL	COIL, CLN80: Coilin	0.032	0.052
CBLC	CBLC, CBL3, RNF57: Signal transduction protein CBL-C	0.032	0.026
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.032	0.026
YAP1	YAP1, YAP65: 65 kDa Yes-associated protein	0.032	0.055
SMARCC2	N/A	0.032	0.032
MARK2	N/A	0.032	0.052
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.032	0.032
XRCC4	N/A	0.032	0.026
BACH1	BACH1: Transcription regulator protein BACH1	0.032	0.0425
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.032	0.026
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.032	0.052
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.032	0.0425
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.032	0.0425
NUP214	N/A	0.032	0.155
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.032	0.052
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.032	0.032
ID2	ID2: DNA-binding protein inhibitor ID-2	0.032	0.0425
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.032	0.0425
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	0.032	0.078
CASP3	CASP3, CPP32: Caspase-3 precursor	0.032	0.114
TLN1	TLN1: Uncharacterized protein TLN1	0.032	0.046
EEF1A1	EEF1A1: Elongation factor 1-alpha	0.032	0.046
GSTP1	GSTP1, FAEES3, GST3: Glutathione S-transferase P	0.032	0.139
EEF2	EEF2, EF2: Elongation factor 2	0.032	0.188
USP10	USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10	0.032	0.078
SEC24B	SEC24B: Protein transport protein Sec24B	0.032	0.046
GSR	GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor	0.032	0.063
TPT1	TPT1: Translationally-controlled tumor protein	0.032	0.046
NME2	NME2, NM23B: Nucleoside diphosphate kinase B	0.032	0.046
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.032	0.078
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.032	0.046
GAPD	GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase	0.032	0.046
RPS3	RPS3, OK/SW-cl.26: 40S ribosomal protein S3	0.032	0.046
FLII	FLII, FLIL: Protein flightless-1 homolog	0.032	0.078
CAD	CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase	0.032	0.046
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.032	0.046
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.032	0.078
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.032	0.078
PPARBP	N/A	0.032	0.046
RAP1A	RAP1A, KREV1: Ras-related protein Rap-1A precursor	0.032	0.139
UBE2E3	UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3	0.032	0.063
PTPN11	N/A	0.032	0.038
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.032	0.063
CRK	N/A	0.032	0.038
NRAS	NRAS, HRAS1: GTPase NRas precursor	0.032	0.139
PRDX1	PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1	0.032	0.114
CTPS	CTPS: CTP synthase 1	0.032	0.038
SHC1	SHC1, RP11-307C12.1-001, hCG_1997126: SHC	0.032	0.038
FER1L3	FER1L3, KIAA1207, MYOF: Myoferlin	0.032	0.054
ACTG1	ACTB: Actin, cytoplasmic 1	0.032	0.063
PPP1CB	PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit	0.032	0.114
ENO1	ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase	0.032	0.046
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.032	0.114
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.032	0.046
KPNB1	KPNB1, NTF97: Importin subunit beta-1	0.032	0.037
ACVR1B	ACVR1B, ACVRLK4: Activin receptor type-1B precursor	0.030	0.036
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.029	0.038
KCTD12	KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12	0.029	0.038
PSKH1	PSKH1: Serine/threonine-protein kinase H1	0.029	0.029
AHR	AHR: Aryl hydrocarbon receptor precursor	0.029	0.029
CXorf9	N/A	0.029	0.038
USP34	USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34	0.029	0.029
ETS1	ETS1, EWSR2: Protein C-ets-1	0.029	0.029
JUNB	JUNB: Transcription factor jun-B	0.029	0.046
CCNL1	CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1	0.029	0.038
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.029	0.035
CREBBP	CREBBP, CBP: CREB-binding protein	0.029	0.038
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.029	0.038
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.029	0.063
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.029	0.038
CLASP1	CLASP1, KIAA0622, MAST1: CLIP-associating protein 1	0.029	0.038
STK10	STK10: Uncharacterized protein STK10	0.029	0.046
GIT1	GIT1: ARF GTPase-activating protein GIT1	0.029	0.029
AGTPBP1	AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein	0.029	0.029
JUND	JUND: Transcription factor jun-D	0.029	0.046
NFKBIA	NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha	0.029	0.046
ZNF76	ZNF76, D6S229E: Zinc finger protein 76	0.029	0.032
SGK	SGK, SGK1: Serine/threonine-protein kinase Sgk1	0.029	0.096
KIAA0690	N/A	0.029	0.029
FOS	FOS, G0S7: Proto-oncogene protein c-fos	0.029	0.038
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.029	0.029
RANBP9	RANBP9, RANBPM: Ran-binding protein 9	0.029	0.029
CEBPB	CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta	0.029	0.046
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.029	0.114
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.029	0.049
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.029	0.038
SGK3	SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3	0.029	0.127
SOX4	SOX4: Transcription factor SOX-4	0.029	0.029
ZNF335	ZNF335: Zinc finger protein 335	0.029	0.029
MDN1	MDN1, KIAA0301: Midasin	0.029	0.114
DUSP1	DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1	0.029	0.052
TCF8	ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1	0.029	0.038
PAK4	PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4	0.029	0.038
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.029	0.086
COL1A2	COL1A2: Collagen alpha-2(I) chain precursor	0.029	0.029
COL5A2	COL5A2: Collagen alpha-2(V) chain precursor	0.029	0.029
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.0286	0.041
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.028
RAB4A	N/A	0.028	0.083
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
MAPKAPK5	N/A	0.028	0.028
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.028	0.028
C20orf18	N/A	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
DSP	DSP: Desmoplakin	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.028	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.083
C13orf8	N/A	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.083
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.028
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
ZNF265	N/A	0.028	0.028
NF2	NF2, SCH: Merlin	0.028	0.028
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.028	0.083
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
CORO6	N/A	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
PPEF1	N/A	0.028	0.083
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.028
UHRF1		0.028	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.028
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.028	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.083
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.028
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
SYTL4	Endocrine transmitter regulatory protein	0.028	0.052
PHLDB2	N/A	0.028	0.028
MAPK15	N/A	0.028	0.028
KIF1B	N/A	0.028	0.028
SNRPB	N/A	0.028	0.028
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.028	0.028
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.028
CABLES1	N/A	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
IRF7	N/A	0.028	0.028
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.028	0.028
KLC2	KLC2: Kinesin light chain 2	0.028	0.056
DNM2	N/A	0.027	0.144
FUBP1	N/A	0.027	0.052
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.027	0.052
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.027	0.032
IFI35	N/A	0.027	0.087
SQSTM1	SQSTM1: Uncharacterized protein SQSTM1	0.027	0.052
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.027	0.070
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.027	0.0425
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.027	0.0425
FLNA	FLNA, FLN, FLN1: Filamin-A	0.027	0.070
VAV2	VAV2, RP11-153P4.1-003: Vav 2 oncogene	0.027	0.0425
SH3BP3		0.026	0.077
RBM6	RBM6, DEF3: RNA-binding protein 6	0.026	0.032
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.026	0.032
GRLF1	N/A	0.026	0.077
NFATC1	N/A	0.026	0.032
IRS2	IRS2: Insulin receptor substrate 2	0.026	0.026
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.026	0.032
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.026	0.0425
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.026	0.0425
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.026	0.026
PER2	PER2, KIAA0347: Period circadian protein homolog 2	0.026	0.026
CEBPA	CEBPA: CCAAT/enhancer-binding protein alpha	0.026	0.026
MEF2A	N/A	0.026	0.096
PRKAA1	N/A	0.026	0.032
STAT2	STAT2: Signal transducer and activator of transcription 2	0.026	0.026
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
CAMK2A	N/A	0.025	0.025
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.075
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.025	0.025
CDC2	CDC2: Cell division control protein 2 homolog	0.025	0.025
NIPBL	N/A	0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
CAMKK1	N/A	0.025	0.025
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.075
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.025	0.075
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
SEC13L1	N/A	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.025
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.025
BRD4	N/A	0.025	0.025
NUP98	N/A	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025
MAX	MAX: Protein max	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.075
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.025
HTATIP	N/A	0.025	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.075
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.025	0.083
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
FLJ23436	N/A	0.025	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.025	0.075
MAP2K3	N/A	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.075
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.025	0.075
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.025
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.025
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.025
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
DIDO1	N/A	0.025	0.025
GRK6	N/A	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.075
NES	N/A	0.025	0.028
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.025
CCNT2	CCNT2: Cyclin-T2	0.025	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.025
TFAP4	TFAP4: Transcription factor AP-4	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.025
SON		0.025	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.025	0.025
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.025	0.025
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.025
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
BCOR	N/A	0.025	0.025
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.075
SOX8	SOX8: Transcription factor SOX-8	0.025	0.025
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.025
ELMO1	N/A	0.025	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.025
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
RNF20		0.025	0.075
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.025
C20orf77	N/A	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
TCEA1	N/A	0.025	0.025
KCTD1		0.025	0.025
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.025	0.025
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.025	0.025
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.025	0.025
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.025	0.025
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.025	0.025
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.075
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.025	0.075
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.025
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.025	0.025
LMNA	LMNA, LMN1: Lamin-A/C	0.025	0.025
ATXN2L	N/A	0.025	0.025
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.025	0.025
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
PRKCB1	N/A	0.025	0.025
GIT2	N/A	0.025	0.025
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.025
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025

0.347

Total Score

26.00