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Evidence of Interaction Between FOXO1A and CREBBP

The interaction score between FOXO1A and CREBBP is 20.40.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between FOXO1A and CREBBP = 0.27

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 2.88E-3
Orthology
OrganismFOXO1A OrthologueCREBBP OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
worm Q86S42 0.285 P34545 0.421

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.22E-3
Domains Domains present in FOXO1A and CREBBP:
Domains in FOXO1ADomains in CREBBP
IPR001766 Fork head transcription factor
IPR011991 Wing_hlx_DNA_bd.
IPR001487 Bromodomain
IPR000197 TAZ finger
IPR000433 Zn-finger, ZZ type
IPR003101 Coactivator CBP, KIX
IPR009255 Protein of unknown function DUF906
IPR010303 Protein of unknown function DUF902

The Chi square scores for co-occurrence of domains that are present in FOXO1A and CREBBP are listed below.

Domain 1Domain 2Chi Square
IPR011991 Wing_hlx_DNA_bd. IPR001487 Bromodomain 0.956527

The background colour of the table refers to:

  • Blue Domain is only present in FOXO1A
  • Yellow Domain is only present in CREBBP
  • Green Domain is present in both FOXO1A and CREBBP

 0.165
Post-translational Modifications

Protein: FOXO1A

PTMResidueReference
Phosphorylation 24 PubMed, HPRD
Phosphorylation 256 PubMed, HPRD
Phosphorylation 319 PubMed, HPRD
Phosphorylation 322 PubMed, HPRD
Phosphorylation 325 PubMed, HPRD
Phosphorylation 329 PubMed, HPRD
Phosphoserine 256 PubMed, HPRD
Phosphoserine 319 PubMed, HPRD
Phosphothreonine 24 PubMed, HPRD

Protein: CREBBP

PTMResidueReference
Methylation 702 PubMed, HPRD
Methylation 714 PubMed, HPRD
Methylation 742 PubMed, HPRD
Methylation 768 PubMed, HPRD
Phosphorylation 302 PubMed, HPRD
Phosphorylation 437 PubMed, HPRD
Localisation

Protein: FOXO1A

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: CREBBP

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between FOXO1A and CREBBP that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between FOXO1A andCREBBP. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , FOXO1A has 805 interactors and CREBBP has 1102 interactors of which there are 697 common interactors.

Common InteractorName of Common InteractorScore for FOXO1A-Interactor (?)Score for CREBBP-Interactor (?)
NFATC1 N/A 0.416 0.127
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.372 0.063
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.307 0.275
IRF3 IRF3: Interferon regulatory factor 3 0.307 0.307
TGIF2 TGIF2: Homeobox protein TGIF2 0.307 0.251
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.275 0.372
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.251 0.251
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.225 0.114
JUNB JUNB: Transcription factor jun-B 0.225 0.275
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.225 0.275
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.225 0.188
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.225 0.114
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.225 0.171
SATB1 SATB1: DNA-binding protein SATB1 0.225 0.225
JUND JUND: Transcription factor jun-D 0.225 0.372
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.225 0.046
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.225 0.118
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.225 41.40
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.225 90.40
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.216 0.158
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.210 0.210
SP100 N/A 0.210 0.307
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.191 0.251
NBN NBN, NBS, NBS1, P95: Nibrin 0.191 0.210
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.188 0.063
ATM ATM: Serine-protein kinase ATM 0.188 0.038
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.171 0.046
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.171 0.275
BRPF1 BRPF1, BR140: Peregrin 0.171 0.114
JUN JUN: Transcription factor AP-1 0.171 0.225
CUTL1 CUTL1: Homeobox protein cut-like 1 0.165 0.165
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.165 0.083
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.165 0.165
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.165 0.165
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.165 0.083
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.165 0.165
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.155 0.188
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.155 0.046
ELF1 ELF1: ETS-related transcription factor Elf-1 0.155 0.416
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.152 0.307
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.152 0.251
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.152 0.096
RB1 RB1: Retinoblastoma-associated protein 0.152 0.0425
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.152 0.136
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.152 0.251
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.152 0.127
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.152 0.251
BACH1 BACH1: Transcription regulator protein BACH1 0.152 0.416
RBL1 RBL1: Retinoblastoma-like protein 1 0.148 0.025
CCNT2 CCNT2: Cyclin-T2 0.148 0.025
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.148 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.148 0.025
BRD4 N/A 0.148 0.047
DLX3 DLX3: Homeobox protein DLX-3 0.148 0.148
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.148 0.148
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.148 0.075
CREB1 CREB1: cAMP response element-binding protein 0.148 0.148
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.148 0.148
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.139 0.063
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.139 0.225
RPS6KB1 N/A 0.139 0.046
ETS1 ETS1, EWSR2: Protein C-ets-1 0.139 0.225
RERE RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei 0.136 0.275
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.136 0.225
CCNH CCNH: Cyclin-H 0.136 0.029
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.127 0.307
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.127 0.114
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.127 0.052
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.127 0.127
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.127 0.188
RELA RELA, NFKB3: Transcription factor p65 0.127 0.188
ZFX ZFX: Zinc finger X-chromosomal protein 0.127 0.096
YY1 YY1: Transcriptional repressor protein YY1 0.127 0.188
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.123 0.225
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.123 0.225
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.123 0.109
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.118 0.188
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.114 0.038
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.114 0.188
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.114 0.114
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.114 0.086
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.114 111.00
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.114 0.046
STAT4 STAT4: Signal transducer and activator of transcription 4 0.114 0.086
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.114 0.139
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.114 0.046
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.114 0.038
ZNF335 ZNF335: Zinc finger protein 335 0.114 0.114
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.114 0.046
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.114 0.275
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.114 0.171
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.114 0.136
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.063
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.110 0.087
GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 0.110 26.00
PCAF PCAF: Histone acetyltransferase PCAF 0.110 0.054
NFIB N/A 0.109 0.055
MAFG MAFG: Transcription factor MafG 0.109 0.171
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.109 0.060
MYB MYB: Myb proto-oncogene protein 0.109 0.123
ZHX3 ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3 0.109 0.123
MYBL2 MYBL2, BMYB: Myb-related protein B 0.109 0.110
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.109 0.096
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.109 0.251
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.109 0.136
TAF1 TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1 0.109 0.039
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.109 0.152
CDX2 CDX2, CDX3: Homeobox protein CDX-2 0.109 0.088
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.109 0.123
RFX1 RFX1: MHC class II regulatory factor RFX1 0.097 0.097
HOXB6 HOXB6, HOX2B: Homeobox protein Hox-B6 0.097 0.088
FOXL2 FOXL2: Forkhead box protein L2 0.097 0.097
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.097 0.136
ID2 ID2: DNA-binding protein inhibitor ID-2 0.096 0.155
XRCC1 XRCC1: DNA-repair protein XRCC1 0.096 0.0425
HIVEP1 N/A 0.096 0.127
H1FX H1FX: Histone H1x 0.096 0.251
MATR3 MATR3, KIAA0723: Matrin-3 0.096 0.127
ROCK1 ROCK1: Rho-associated protein kinase 1 0.096 0.155
SATB2 SATB2, KIAA1034: DNA-binding protein SATB2 0.088 0.097
NKX2-5 NKX2-5, CSX, NKX2.5, NKX2E: Homeobox protein Nkx-2.5 0.088 0.088
EN2 EN2: Homeobox protein engrailed-2 0.088 0.136
SOS1 SOS1: Son of sevenless homolog 1 0.087 0.139
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.086 0.114
SP3 SP3: Transcription factor Sp3 0.086 0.233
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.086 0.171
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.086 0.275
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.086 0.038
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.086 0.038
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.086 0.029
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.086 0.029
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.086 0.372
PPP1R8 N/A 0.086 0.046
MTF1 MTF1: Metal regulatory transcription factor 1 0.086 0.139
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.083 0.083
ZNF579 ZNF579: Zinc finger protein 579 0.083 0.083
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.028
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.083 0.083
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.083 0.083
SOX8 SOX8: Transcription factor SOX-8 0.083 0.025
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.028
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.083 0.075
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.083 0.165
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.083 0.165
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.083 0.083
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.083 35.90
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.083 0.025
SP140 SP140, LYSP100: Nuclear body protein SP140 0.083 0.0308
STAT6 STAT6: Signal transducer and activator of transcription 6 0.0818 66.00
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.080 0.087
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.077 0.038
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.077 0.225
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.077 0.114
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.077 0.136
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.077 0.0425
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.077 0.062
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.077 0.062
SAT SAT1, SAT: Diamine acetyltransferase 1 0.077 0.0425
MEF2A N/A 0.077 0.052
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.075 0.075
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.025
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.075 0.075
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.025
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.075 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.075 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.075 0.075
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.025
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.075 0.075
TFAP4 TFAP4: Transcription factor AP-4 0.075 0.075
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.028
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.025
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.075 0.148
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.075 0.075
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.025
NIPBL N/A 0.075 0.025
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.075 35.90
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.075 0.075
ELMO1 N/A 0.075 0.075
RNF20 0.075 0.025
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.075 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.075 0.025
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.074 0.057
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.070 0.0971
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.210
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.070 0.046
NCOA3 N/A 0.070 0.052
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.070 0.052
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.069 0.110
SNAI1 SNAI1, SNAH: Zinc finger protein SNAI1 0.069 0.056
SRF SRF: Serum response factor 0.069 0.038
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.069 0.029
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.069 0.063
PPARG CREB3L2-PPARgamma 0.069 0.110
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 0.069 0.110
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.069 0.029
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.069 0.029
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.069 0.029
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.069 0.188
ZBTB16 ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16 0.069 0.056
SP110 SP110: Sp110 nuclear body protein 0.067 0.067
ZHX2 ZHX2, AFR1, KIAA0854, RAF: Zinc fingers and homeoboxes protein 2 0.067 0.041
PAX5 PAX5: Paired box protein Pax-5 0.067 13.20
EXOC2 N/A 0.067 0.067
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.064 0.027
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.063 0.139
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.063 0.063
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.063 0.046
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.062 0.055
ZNF267 ZNF267: Zinc finger protein 267 0.062 0.307
STAT2 STAT2: Signal transducer and activator of transcription 2 0.062 0.096
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.062 0.026
PGR PGR, NR3C3: Progesterone receptor 0.062 0.109
ERF ERF: ETS domain-containing transcription factor ERF 0.062 0.191
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.062 0.026
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.062 41.40
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.062 0.096
SH3BP3 0.062 0.127
ETS2 ETS2: Protein C-ets-2 0.062 0.191
ERG ERG: Transcriptional regulator ERG 0.062 0.123
GTF2F2 N/A 0.062 0.152
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.061 0.091
TP53 TP53, P53: Cellular tumor antigen p53 0.060 0.086
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.060 0.210
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.060 41.40
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.060 0.251
HD HD, IT15: Huntingtin 0.057 0.075
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.056 65.60
MTA1 MTA1: Metastasis-associated protein MTA1 0.056 0.114
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.056 0.029
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.056 0.038
AHR AHR: Aryl hydrocarbon receptor precursor 0.056 0.086
MEF2C MEF2C: Myocyte-specific enhancer factor 2C 0.056 11.10
ZNF551 N/A 0.056 0.136
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.056 0.136
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.056 0.139
SP1 SP1, TSFP1: Transcription factor Sp1 0.056 33.10
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.056 0.046
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.056 0.038
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.056 0.056
MYF5 MYF5: Myogenic factor 5 0.056 0.049
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.056 0.088
MYCN MYCN, NMYC: N-myc proto-oncogene protein 0.055 0.069
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.026
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.055 0.026
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.055 0.123
BNC1 BNC1, BNC: Zinc finger protein basonuclin-1 0.055 0.044
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.055 0.251
RASA3 RASA3: Ras GTPase-activating protein 3 0.054 0.041
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.054 0.111
VAV1 VAV1, VAV: Proto-oncogene vav 0.054 0.111
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.054 0.233
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.054 0.046
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.054 0.114
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.052 0.075
HES6 HES6: Transcription cofactor HES-6 0.052 0.083
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.052 0.083
MAPK15 N/A 0.052 0.028
C20orf18 N/A 0.052 0.083
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.052 0.028
RBM6 RBM6, DEF3: RNA-binding protein 6 0.052 0.0425
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.052 0.052
MARK2 N/A 0.052 0.052
IFI16 N/A 0.052 0.052
PTMA N/A 0.052 0.052
GNB2L1 Lung cancer oncogene 7 0.052 0.052
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.052 0.096
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.052 0.0425
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.052 0.052
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.052 0.0425
ATF2 N/A 0.051 0.051
SMARCC1 SMARCC1, BAF155: SWI/SNF-related matrix-associated actin-dependent regulator of 0.051 0.051
EP400 N/A 0.051 0.051
NCOR2 NCOR2, CTG26: Nuclear receptor corepressor 2 0.051 0.046
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.051 0.111
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.051 0.032
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.051 0.032
ELK1 ELK1: ETS domain-containing protein Elk-1 0.050 0.110
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.050 0.049
BACH2 BACH2: Transcription regulator protein BACH2 0.050 0.0308
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.049 0.110
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.049 26.80
HAND1 HAND1, EHAND: Heart- and neural crest derivatives-expressed protein 1 0.049 23.60
ETV1 ETV1, ER81: ETS translocation variant 1 0.049 0.109
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.049 0.123
TAL1 TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1 0.049 0.056
YWHAG YWHAG: 14-3-3 protein gamma 0.049 0.0333
VDR VDR, NR1I1: Vitamin D3 receptor 0.049 0.136
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.049 0.038
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.049 53.10
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.049 0.046
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.049 0.029
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.049 0.097
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.049 0.097
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.049 0.029
HES1 HES1, HL, HRY: Transcription factor HES-1 0.049 0.044
SYMPK SYMPK, SPK: Symplekin 0.049 0.029
EGR1 EGR1, ZNF225: Early growth response protein 1 0.049 0.056
KLF5 KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5 0.049 0.044
KIAA0690 N/A 0.049 0.038
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.048 0.114
DOK1 DOK1: Docking protein 1 0.048 0.139
PLEK PLEK, P47: Pleckstrin 0.048 0.155
IRS1 IRS1: Insulin receptor substrate 1 0.048 0.062
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.048 0.127
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.047 0.075
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.047 0.137
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.047 0.075
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.047 0.075
MAX MAX: Protein max 0.047 0.075
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.046 0.063
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.046 0.046
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.046 0.046
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.046 0.188
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.046 0.046
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.038
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.046 0.046
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.046 0.038
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.046 0.063
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.046 0.046
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.046 0.063
KIAA1012 KIAA1012: Protein TRS85 homolog 0.046 0.063
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.046 0.038
PHF10 N/A 0.046 0.114
WBSCR20A N/A 0.046 0.046
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.046 0.087
FNBP1 N/A 0.046 0.063
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.046 0.067
PBX3 PBX3: Pre-B-cell leukemia transcription factor 3 0.044 0.028
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.044 0.097
SALL1 SALL1, SAL1: Sal-like protein 1 0.044 0.049
STAT3 0.044 0.044
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.043 0.063
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.043 0.038
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.0425 0.0425
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.0425 0.032
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.0425 0.063
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.0425 0.0425
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.0425 0.416
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.0425 0.046
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.0425 0.046
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.0425 0.0425
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.0425 0.032
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.0425 0.0425
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.032
CXorf9 N/A 0.0425 0.046
KIAA0853 N/A 0.0425 0.052
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.041 0.041
PSCD4 PSCD4, CYT4: Cytohesin-4 0.041 0.0818
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.041 0.051
ATXN7 ATXN7, SCA7: Ataxin-7 0.0407 0.0407
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.041 77.30
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.041 0.067
RFX5 RFX5: DNA-binding protein RFX5 0.041 0.050
RNF31 ISGF3G, IRF9: Transcriptional regulator ISGF3 subunit gamma 0.041 0.083
MYBL1 MYBL1, AMYB: Myb-related protein A 0.041 0.036
C14orf106 C14orf106, KIAA1903: Uncharacterized potential DNA-binding protein C14orf106 0.041 0.050
LNK SH2B3, LNK: SH2B adapter protein 3 0.04 0.049
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.04 0.049
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.04 0.044
DNM3 DNM3: Uncharacterized protein DNM3 0.04 0.049
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.04 0.044
PSCD2 N/A 0.04 0.049
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.04 0.049
IRS2 IRS2: Insulin receptor substrate 2 0.039 0.127
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.038 0.046
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.038 0.046
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.038 0.038
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.038 0.038
SEC31L1 N/A 0.038 0.038
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.038 0.046
STK10 STK10: Uncharacterized protein STK10 0.038 0.063
KLHDC4 N/A 0.038 0.046
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.038 0.063
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.038 0.063
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.038 0.046
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.038 0.046
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.038 0.046
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.038 0.078
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.038 0.046
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.038 0.086
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.038 0.063
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.038 0.038
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.038 0.038
CUL4B N/A 0.038 0.038
MYH9 MYH9: Myosin-9 0.038 0.275
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.038 0.038
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.038 0.046
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.038 0.114
SAPS3 N/A 0.038 0.038
CUL5 CUL5, VACM1: Cullin-5 0.038 0.046
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.038 0.063
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.038 0.188
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.037 0.033
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.037 0.037
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.037 0.057
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.037 0.100
GTF2E2 GTF2E2, TF2E2: Transcription initiation factor IIE subunit beta 0.036 0.036
FOXP1 FOXP1, HSPC215: Forkhead box protein P1 0.036 0.036
HHEX HHEX, HEX, PRH, PRHX: Homeobox protein PRH 0.036 0.028
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.036 0.074
ARHGEF7 N/A 0.036 0.044
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.036 0.098
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.036 0.044
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.036 0.044
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.035 0.038
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.035 0.055
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.034 0.062
GAB1 GAB1: GRB2-associated-binding protein 1 0.034 0.077
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.033 0.067
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.033 4.05
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.032 13.60
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.032 0.052
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.032 0.038
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.032 0.0425
VIM VIM: Vimentin 0.032 0.026
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.032 0.052
API5 N/A 0.032 0.032
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.032 0.070
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.032 0.071
ABCF1 N/A 0.032 0.0425
RBM14 RBM14, SIP: RNA-binding protein 14 0.032 0.052
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.0425
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.032 0.038
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.032 0.0425
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.032 0.0425
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.032 0.0425
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.032 0.344
WDR1 N/A 0.032 0.052
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.032 0.063
PRKAA1 N/A 0.032 0.032
HDAC3 HDAC3: Histone deacetylase 3 0.032 0.071
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.032 0.046
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.032 0.052
ARFGAP1 N/A 0.032 0.0425
AFF1 N/A 0.032 0.0425
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.060
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.032 0.052
TOP2B N/A 0.032 0.052
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.032 0.052
DDX21 DDX21: Nucleolar RNA helicase 2 0.032 0.0425
SET SET: Protein SET 0.032 0.032
NCK2 NCK2: Cytoplasmic protein NCK2 0.032 0.032
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.032 0.067
VIL2 N/A 0.032 0.054
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.031 0.069
GAB2 N/A 0.031 0.127
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.0308 0.029
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.0308 0.026
ADNP ADNP, ADNP1, KIAA0784: Activity-dependent neuroprotector 0.0308 0.067
MAF MAF: Transcription factor Maf 0.0308 0.028
APS SH2B2, APS: SH2B adapter protein 2 0.030 0.067
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.046
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.029 0.046
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.029 0.038
MDN1 MDN1, KIAA0301: Midasin 0.029 0.029
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.029 0.046
DIAPH1 Diaphanous 1 0.029 0.063
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.029 0.046
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.029 0.038
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.029 0.046
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.029 0.029
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.029 0.038
AIP AIP, XAP2: AH receptor-interacting protein 0.029 0.046
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.029 0.063
NUP153 N/A 0.029 0.038
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.029 0.078
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.029 0.038
EP300 N/A 0.029 0.063
NOL1 N/A 0.029 0.038
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.029 0.029
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.029 0.046
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.029 0.063
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.029 0.038
WDR44 WDR44: WD repeat-containing protein 44 0.029 0.038
TIAL1 TIAL1: Nucleolysin TIAR 0.029 0.046
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.029 0.038
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.029 0.078
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.029 0.046
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.029 0.038
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.029 0.038
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.029 0.038
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.029 0.038
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.029 0.029
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.029 0.038
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.028 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.028 0.025
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
RAB4A N/A 0.028 0.028
CETN1 CETN1, CEN1, CETN: Centrin-1 0.028 0.075
BID BID: BH3-interacting domain death agonist 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.028 0.025
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.028 0.025
MAPKAPK5 N/A 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.028 0.148
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.028 0.025
SNRPB N/A 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
CABLES1 N/A 0.028 0.028
KIF1B N/A 0.028 0.028
IRF7 N/A 0.028 0.028
NF2 NF2, SCH: Merlin 0.028 0.052
UHRF1 0.028 0.083
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
ZNF598 ZNF598: Zinc finger protein 598 0.028 0.025
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.028 0.025
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.028 0.152
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
HDAC8 N/A 0.028 0.052
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.083
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.028 0.025
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.028
CORO6 N/A 0.028 0.028
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.028 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.028 0.148
GEMIN5 GEMIN5: Gem-associated protein 5 0.028 0.025
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.028 0.025
DUSP15 N/A 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.028
PHLDB2 N/A 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.165
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
C13orf8 N/A 0.028 0.028
KCTD1 0.028 0.025
PPEF1 N/A 0.028 0.083
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.083
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
ZNF265 N/A 0.028 0.028
NHN1 NHN1: Conserved nuclear protein NHN1 0.028 0.025
WDR54 N/A 0.028 0.028
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.028 0.025
SYTL4 Endocrine transmitter regulatory protein 0.028 0.028
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.083
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.028 0.029
SMARCA1 SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1 0.028 0.044
HOXA7 HOXA7, HOX1A: Homeobox protein Hox-A7 0.028 0.036
PKNOX1 PKNOX1, PREP1: Homeobox protein PKNOX1 0.028 0.028
CUTL2 CUTL2, KIAA0293: Homeobox protein cut-like 2 0.0273 0.030
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.027 0.0818
PLD1 PLD1: Phospholipase D1 0.027 0.029
DUX2 DUX2: Putative double homeobox protein 2 0.027 0.027
TGIF2LX TGIF2LX, TGIFLX: Homeobox protein TGIF2LX 0.027 0.027
POU3F3 POU3F3, BRN1, OTF8: POU domain, class 3, transcription factor 3 0.027 11.50
HOXC12 HOXC12, HOC3F, HOX3F: Homeobox protein Hox-C12 0.027 0.027
PITX2 PITX2, ARP1, RGS, RIEG, RIEG1: Pituitary homeobox 2 0.027 0.027
TSHZ2 TSHZ2, C20orf17, TSH2, ZNF218: Teashirt homolog 2 0.027 0.027
DUX4 FSHD, DUX4: Facioscapulohumeral muscular dystrophy 0.027 0.027
FOXQ1 FOXQ1, HFH1: Forkhead box protein Q1 0.027 0.027
TSHZ3 TSHZ3, KIAA1474, TSH3, ZNF537: Teashirt homolog 3 0.027 0.027
TSHZ1 TSHZ1, SDCCAG33, TSH1: Teashirt homolog 1 0.027 0.027
DLX4 DLX4, BP1, DLX7, DLX8, DLX9: Homeobox protein DLX-4 0.027 0.027
SHOX SHOX, PHOG: Short stature homeobox protein 0.027 0.027
SHOX2 SHOX2, OG12X, SHOT: Short stature homeobox protein 2 0.027 0.027
OTEX RHOXF1, OTEX, PEPP1: Rhox homeobox family member 1 0.027 0.027
POU5F1 POU5F1, OCT3, OCT4, OTF3: POU domain, class 5, transcription factor 1 0.027 0.027
PAX3 PAX3, HUP2: Paired box protein Pax-3 0.027 0.027
OTX2 OTX2: Homeobox protein OTX2 0.027 0.027
HOXD8 HOXD8, HOX4E: Homeobox protein Hox-D8 0.027 0.027
FLJ25680 POU5F2, SPRM1: POU domain, class 5, transcription factor 2 0.027 0.027
CREM hCREM-1: HCREM 1alpha protein 0.027 0.027
GSCL GSCL: Homeobox protein goosecoid-like 0.027 0.027
TGIF N/A 0.027 0.027
TGIF2LY TGIF2LY, TGIFLY: Homeobox protein TGIF2LY 0.027 0.027
CREM CREM, RP11-324I22.1-005: cAMP responsive element modulator 0.027 0.027
FUBP1 N/A 0.027 0.027
CASP8 N/A 0.027 0.036
BMX N/A 0.0263 0.032
MCF2 MCF2, DBL: Proto-oncogene DBL 0.0263 0.072
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.026 0.052
GTF3C1 N/A 0.026 0.0425
RGS14 N/A 0.026 0.052
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.026 0.032
OSR2 N/A 0.026 0.026
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.026 0.0425
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.026 0.052
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.026 0.046
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.026 0.032
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.026 0.032
CHUK N/A 0.026 0.0425
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.026 0.0425
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.026 0.032
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.026 0.0425
TCOF1 N/A 0.026 0.0425
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.026 0.0425
SMARCC2 N/A 0.026 0.052
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.026 0.026
COIL COIL, CLN80: Coilin 0.026 0.032
TRRAP N/A 0.026 0.0425
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.026 0.029
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.026 0.029
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.026 0.032
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.026 0.029
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.026 0.038
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.025 0.039
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
ATXN2L N/A 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
TCEA1 N/A 0.025 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
PRKCB1 N/A 0.025 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.075
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.025 0.025
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.075
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.025
CAMKK1 N/A 0.025 0.025
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.075
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.025
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.025 0.137
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.025
NUP98 N/A 0.025 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.025
GIT2 N/A 0.025 0.025
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.075
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.025 0.025
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.025
GRK6 N/A 0.025 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
SON 0.025 0.025
FLJ23436 N/A 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.025 0.025
EEF2K EEF2K: Elongation factor 2 kinase 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.075
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.025 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.075
HDAC7A N/A 0.025 0.025
DIDO1 N/A 0.025 0.075
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.025
HTATIP N/A 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
NES N/A 0.025 0.028
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
C20orf77 N/A 0.025 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.025 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.025
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.075
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.025
SEC13L1 N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
CAMK2A N/A 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
0.299
Total Score 20.40