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Evidence of Interaction Between F9 and PLA2G7

The interaction score between F9 and PLA2G7 is 26.60.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between F9 and PLA2G7 = 0.05

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.85E-3
Orthology
OrganismF9 OrthologuePLA2G7 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00019576 0.279 IPI00015388 0.149

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.22E-3
Domains Domains present in F9 and PLA2G7:
Domains in F9Domains in PLA2G7
IPR000152 Aspartic acid and asparagine hydroxylation site
IPR001881 EGF-like calcium-binding
IPR006209 EGF-like domain
IPR006210 Type I EGF
IPR001438 Type II EGF-like signature
IPR001254 Peptidase S1, chymotrypsin
IPR001314 Peptidase S1A, chymotrypsin
IPR009003 Peptidase, trypsin-like serine and cysteine proteases
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region
IPR002383 Coagulation factor, Gla region
IPR000742 EGF_2.
IPR013032 IPR006209.
IPR012224 Pept_S1A_FX.
IPR008262 Lipase, active site
IPR005065 Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II
IPR000379 Esterase/lipase/thioesterase

The Chi square scores for co-occurrence of domains that are present in F9 and PLA2G7 are listed below.

Domain 1Domain 2Chi Square
IPR000152 Aspartic acid and asparagine hydroxylation site IPR000379 Esterase/lipase/thioesterase 22.3642
IPR000152 Aspartic acid and asparagine hydroxylation site IPR008262 Lipase, active site 16.5154
IPR001881 EGF-like calcium-binding IPR008262 Lipase, active site 16.0828
IPR006209 EGF-like domain IPR000379 Esterase/lipase/thioesterase 12.4701
IPR001881 EGF-like calcium-binding IPR000379 Esterase/lipase/thioesterase 11.8563
IPR000742 EGF_2. IPR000379 Esterase/lipase/thioesterase 10.3314
IPR006210 Type I EGF IPR000379 Esterase/lipase/thioesterase 7.81102
IPR000742 EGF_2. IPR008262 Lipase, active site 7.53257
IPR013032 IPR006209. IPR000379 Esterase/lipase/thioesterase 5.73318
IPR006209 EGF-like domain IPR008262 Lipase, active site 5.13532
IPR006210 Type I EGF IPR008262 Lipase, active site 4.49559
IPR013032 IPR006209. IPR008262 Lipase, active site 3.21279

The background colour of the table refers to:

  • Blue Domain is only present in F9
  • Yellow Domain is only present in PLA2G7
  • Green Domain is present in both F9 and PLA2G7

 0.174
Post-translational Modifications

Protein: F9

PTMResidueReference
3-hydroxyaspartate 110 HPRD
4-carboxyglutamate 53 HPRD
4-carboxyglutamate 54 HPRD
4-carboxyglutamate 61 HPRD
4-carboxyglutamate 63 HPRD
4-carboxyglutamate 66 HPRD
4-carboxyglutamate 67 HPRD
4-carboxyglutamate 72 HPRD
4-carboxyglutamate 73 HPRD
4-carboxyglutamate 76 HPRD
4-carboxyglutamate 79 HPRD
4-carboxyglutamate 82 HPRD
4-carboxyglutamate 86 HPRD
Carboxylation 53 PubMed, HPRD
Carboxylation 54 PubMed, HPRD
Carboxylation 61 PubMed, HPRD
Carboxylation 63 PubMed, HPRD
Carboxylation 66 PubMed, HPRD
Carboxylation 67 PubMed, HPRD
Carboxylation 72 PubMed, HPRD
Carboxylation 73 PubMed, HPRD
Carboxylation 76 PubMed, HPRD
Carboxylation 79 PubMed, HPRD
Carboxylation 82 PubMed, HPRD
Carboxylation 86 PubMed, HPRD
Disulfide Bridge 145 PubMed, HPRD
Disulfide Bridge 155 PubMed, HPRD
Disulfide Bridge 170 PubMed, HPRD
Glycosylation 203 PubMed, HPRD
Glycosylation 213 PubMed, HPRD
N-linked 203 PubMed, HPRD
N-linked 213 PubMed, HPRD
O-linked 99 PubMed, HPRD
O-linked 107 PubMed, HPRD
O-linked 205 HPRD
O-linked 215 HPRD
O-linked 218 HPRD
O-linked 225 HPRD
Phosphoserine 114 PubMed, HPRD
Phosphoserine 204 HPRD
Proteolytic Cleavage 191 PubMed, HPRD
Proteolytic Cleavage 226 PubMed, HPRD
Sulfotyrosine 201 HPRD

Protein: PLA2G7

PTMResidueReference
N-linked 433 PubMed, HPRD
Localisation

Protein: F9

LocalisationReference
ER HPRD
Golgi HPRD
Secreted HPRD

Protein: PLA2G7

LocalisationReference
Nucleus HPRD
Secreted HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between F9 and PLA2G7 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between F9 andPLA2G7. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , F9 has 1142 interactors and PLA2G7 has 302 interactors of which there are 271 common interactors.

Common InteractorName of Common InteractorScore for F9-Interactor (?)Score for PLA2G7-Interactor (?)
F2 F2: Prothrombin precursor 386.00 0.102
F10 F10: Coagulation factor X precursor 234.00 0.116
SERPINA7 SERPINA7, TBG: Thyroxine-binding globulin precursor 7.89 0.026
SERPINA1 SERPINA1, AAT, PRO0684, PI, PRO2209: Alpha-1-antitrypsin precursor 7.89 0.0425
SERPINA10 SERPINA10, ZPI, UNQ707/PRO1358: Protein Z-dependent protease inhibitor precursor 4.77 0.026
F5 F5: Coagulation factor V precursor 3.85 0.155
C8B C8B: Complement component C8 beta chain precursor 1.71 0.110
CD14 CD14: Monocyte differentiation antigen CD14 precursor 1.41 0.144
C2 C2: Complement C2 precursor 0.898 0.026
C8A C8A: Complement component C8 alpha chain precursor 0.898 0.123
MBL2 MBL2, MBL: Mannose-binding protein C precursor 0.804 0.102
PTGS1 PTGS1, COX1: Prostaglandin G/H synthase 1 precursor 0.574 0.0688
F12 F12: Coagulation factor XII precursor 0.543 0.123
APCS APCS, PTX2: Serum amyloid P-component precursor 0.543 0.062
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.543 0.123
PROZ PROZ: Vitamin K-dependent protein Z precursor 0.543 0.115
PROC PROC: Vitamin K-dependent protein C precursor 0.486 0.130
C6 C6: Complement component C6 precursor 0.486 0.123
LMAN2 LMAN2, C5orf8: Vesicular integral-membrane protein VIP36 precursor 0.384 0.046
CFI CFI, IF: Complement factor I precursor 0.324 0.152
C1R C1R: Complement C1r subcomponent precursor 0.324 0.123
C9 C9: Complement component C9 precursor [Contains: Complement component C9a; Compl 0.290 0.110
CETP CETP: Cholesteryl ester transfer protein precursor 0.283 0.032
CSF3 CSF3, GCSF: Granulocyte colony-stimulating factor precursor 0.209 0.028
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.209 0.028
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.209 0.028
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.209 0.028
DCN DCN: Decorin precursor 0.209 0.028
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.209 0.028
NULL A1BG: Alpha-1B-glycoprotein precursor 0.209 0.028
KITLG KITLG, MGF, SCF: Kit ligand precursor 0.209 0.028
IL4 IL4: Interleukin-4 precursor 0.209 0.028
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.209 0.028
OPTC OPTC, OPT: Opticin precursor 0.209 0.028
THPO THPO, MGDF: Thrombopoietin precursor 0.209 0.028
IFNG IFNG: Interferon gamma precursor 0.209 0.028
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.201 0.062
CCL14 CCL14, NCC2, SCYA14: Small-inducible cytokine A14 precursor 0.201 0.123
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.201 0.055
CXCL9 CXCL9, CMK, MIG, SCYB9: Small-inducible cytokine B9 precursor 0.201 0.152
PROS1 PROS1, PROS: Vitamin K-dependent protein S precursor 0.201 0.130
C1S C1S: Complement C1s subcomponent precursor 0.201 0.109
SHBG SHBG: Sex hormone-binding globulin precursor 0.201 0.055
CCL1 CCL1, SCYA1: Small-inducible cytokine A1 precursor 0.201 0.109
IL5 IL5: Interleukin-5 precursor 0.192 0.026
CSF2 CSF2, GMCSF: Granulocyte-macrophage colony-stimulating factor precursor 0.192 0.026
CNTN4 CNTN4: Contactin-4 precursor 0.187 0.025
CNTN1 CNTN1: Contactin-1 precursor 0.187 0.025
NTF3 NTF3: Neurotrophin-3 precursor 0.176 0.026
ECM1 ECM1: Extracellular matrix protein 1 precursor 0.174 0.028
CFHR1 CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2: Complement factor H-relate 0.174 0.028
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.174 0.028
C4A C4A: Complement C4-A precursor 0.174 0.028
LOC643930 CCL3L1, D17S1718, G0S19-2, SCYA3L1: Small-inducible cytokine A3-like 1 precursor 0.174 0.165
BGLAP BGLAP: Osteocalcin precursor 0.174 0.152
GRN GRN: Granulins precursor 0.174 0.025
TFPI TFPI, LACI, TFPI1: Tissue factor pathway inhibitor precursor 0.174 0.028
FN1 N/A 0.174 0.028
CCL15 CCL15, MIP5, NCC3, SCYA15: Small-inducible cytokine A15 precursor 0.174 0.165
F11 F11: Coagulation factor XI precursor 0.174 0.028
C1QC C1QC, C1QG: Complement C1q subcomponent subunit C precursor 0.174 0.028
CCL26 CCL26, SCYA26, UNQ216/PRO242: Small-inducible cytokine A26 precursor 0.174 0.165
MMRN2 MMRN2, EMILIN3: Multimerin-2 precursor 0.174 0.028
CD46 N/A 0.165 0.028
C1QTNF4 C1QTNF4, CTRP4: Complement C1q tumor necrosis factor-related protein 4 precursor 0.165 0.028
MMP13 MMP13: Collagenase 3 precursor 0.160 0.026
CCL24 CCL24, MPIF2, SCYA24: Small-inducible cytokine A24 precursor 0.160 0.123
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.160 0.062
COL5A1 N/A 0.160 0.137
THBD THBD, THRM: Thrombomodulin precursor 0.160 0.152
CXCL10 CXCL10, INP10, SCYB10: Small-inducible cytokine B10 precursor 0.160 0.109
CMA1 CMA1, CYH, CYM: Chymase precursor 0.160 0.026
F7 F7: Coagulation factor VII precursor 0.156 0.174
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.156 0.025
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.156 0.025
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.156 0.137
SPOCK1 SPOCK1, SPOCK, TIC1, TICN1: Testican-1 precursor 0.156 0.075
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.156 0.148
BMP1 N/A 0.156 0.148
CPB2 CPB2: Carboxypeptidase B2 precursor 0.156 0.025
PLAT PLAT: Tissue-type plasminogen activator precursor 0.156 0.083
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.156 0.025
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.156 0.025
COL18A1 N/A 0.156 0.028
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.156 0.025
KLK3 KLK3, APS: Prostate-specific antigen precursor 0.156 0.025
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.156 0.026
OSM OSM: Oncostatin-M precursor 0.156 0.032
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.156 0.0425
PTHLH N/A 0.152 0.028
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.152 0.028
GHRL GHRL, MTLRP, UNQ524/PRO1066: Appetite-regulating hormone precursor 0.152 0.028
GUCA2A GUCA2A, GUCA2: Guanylin precursor 0.152 0.028
GRP Gastrin-releasing peptide 0.152 0.028
LECT1 LECT1, CHMI: Chondromodulin-1 precursor 0.152 0.028
CCL14 N/A 0.152 0.028
CSF1 CSF1: Macrophage colony-stimulating factor 1 precursor 0.152 0.028
NOG NOG: Noggin precursor 0.152 0.028
CST4 CST4: Cystatin-S precursor 0.152 0.028
ACCN3 ACCN3, ASIC3, SLNAC1, TNAC1: Amiloride-sensitive cation channel 3 0.152 0.028
PCSK6 N/A 0.152 0.028
PLTP PLTP: Phospholipid transfer protein precursor 0.152 0.025
PLAU Plasminogen activator, urokinase 0.152 0.028
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.144 0.097
THBS1 THBS1, TSP, TSP1: Thrombospondin-1 precursor 0.144 0.097
HLA-DQB2 HLA-DQB2, DASS-256O6.1-002, XXbac-BCX231H22.1-002, XXbac-BPG3L13.3-002: Major hi 0.140 0.032
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.137 0.026
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.137 0.0425
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.137 0.032
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.137 0.052
ITM2C ITM2C, BRI3, hucep-14, NPD018, PSEC0047: Integral membrane protein 2C 0.137 0.025
VNN1 VNN1: Pantetheinase precursor 0.137 0.025
LOC641705 AMY2A: Pancreatic alpha-amylase precursor 0.137 0.025
CA11 CA11, CARP2, UNQ211/PRO237: Carbonic anhydrase-related protein 11 precursor 0.137 0.025
NOTCH4 N/A 0.130 0.097
CXCL11 CXCL11, ITAC, SCYB11, SCYB9B: Small-inducible cytokine B11 precursor 0.130 0.123
CCL11 CCL11, SCYA11: Eotaxin precursor 0.130 0.109
CCL13 CCL13, MCP4, NCC1, SCYA13: Small-inducible cytokine A13 precursor 0.130 0.109
CCL8 CCL8, MCP2, SCYA10, SCYA8: Small-inducible cytokine A8 precursor 0.130 0.123
MUC2 MUC2, SMUC: Mucin-2 precursor 0.130 0.055
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.130 0.088
CXCL12 Stromal cell-derived factor 1 delta 0.130 0.152
CCL2 CCL2, MCP1, SCYA2: Small-inducible cytokine A2 precursor 0.130 0.109
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.130 0.123
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.126 0.081
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.124 0.052
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.124 0.0425
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.124 0.052
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.124 0.052
PF4V1 PF4V1, SCYB4V1: Platelet factor 4 variant precursor 0.123 0.051
CCL7 MCP-3: Monocyte chemotactic protein-3 0.123 0.037
LAMA2 LAMA2: Uncharacterized protein LAMA2 0.116 0.097
C7 C7: Complement component C7 precursor 0.116 0.110
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.116 0.110
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.116 0.097
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.116 0.110
TNC TNC, HXB: Tenascin precursor 0.116 0.097
CPM CPM: Carboxypeptidase M precursor 0.116 0.032
UMOD UMOD: Uromodulin precursor 0.115 0.109
LIPG LIPG, UNQ387/PRO719: Endothelial lipase precursor 0.115 0.026
CCL4 CCL4, CCL4L, LAG1, MIP1B, SCYA4, SCYA4L: Small-inducible cytokine A4 precursor 0.115 0.123
CSPG2 N/A 0.115 0.515
COL15A1 COL15A1: Collagen alpha-1(XV) chain precursor [Contains: Endostatin 0.115 0.055
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.115 0.055
PPBP PPBP, CTAP3, SCYB7, TGB1, THBGB1: Platelet basic protein precursor 0.115 0.251
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.115 0.055
IL8 IL8: Interleukin-8 precursor 0.115 0.251
CXCL5 CXCL5, ENA78, SCYB5: Small-inducible cytokine B5 precursor 0.115 0.123
PF4 PF4, CXCL4, SCYB4: Platelet factor 4 precursor 0.115 0.191
CCL21 CCL21, SCYA21, UNQ784/PRO1600: Small-inducible cytokine A21 precursor 0.115 0.152
TG TG: Thyroglobulin precursor 0.115 0.026
XCL1 XCL1, LTN, SCYC1: Lymphotactin precursor 0.115 0.109
CCL5 CCL5, D17S136E, SCYA5: Small-inducible cytokine A5 precursor 0.115 0.123
TACSTD1 TACSTD1, GA733-2, M1S2, M4S1, MIC18, TROP1: Tumor-associated calcium signal tran 0.115 0.026
CXCL1 CXCL1, GRO, GRO1, GROA, MGSA, SCYB1: Growth-regulated protein alpha precursor 0.115 0.109
CCL22 CCL22, A-152E5.1, MDC, SCYA22: Small-inducible cytokine A22 precursor 0.115 0.109
IL1RN IL1RN, IL1F3, IL1RA: Interleukin-1 receptor antagonist protein precursor 0.114 0.026
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.113 0.029
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.111 0.046
ALK ALK: ALK tyrosine kinase receptor precursor 0.110 0.110
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.109 0.044
IL15RA IL15RA: Interleukin-15 receptor alpha chain precursor 0.109 0.032
LGALS3 LGALS3, MAC2: Galectin-3 0.103 0.127
CFP CFP, PFC: Properdin precursor 0.103 0.144
SLIT2 SLIT2, SLIL3: Slit homolog 2 protein precursor 0.103 0.088
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.103 0.088
RNASE2 RNASE2, EDN, RNS2: Non-secretory ribonuclease precursor 0.100 0.032
GAA GAA: Uncharacterized protein GAA 0.100 0.070
MEP1B MEP1B: Meprin A subunit beta precursor 0.099 0.073
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.098 0.044
DLK1 DLK1, DLK: Delta-like protein precursor 0.096 0.109
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.096 0.109
TMPRSS9 N/A 0.096 0.098
FGL2 FGL2: Fibroleukin precursor 0.093 0.129
CPD CPD: Carboxypeptidase D precursor 0.093 0.029
PSAP PSAP, GLBA, SAP1: Proactivator polypeptide precursor [Contains: Saposin-A 0.090 0.087
CST3 CST3: Cystatin-C precursor 0.090 0.070
HLA-DRA 0.090 0.0425
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.090 0.033
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.088 0.0453
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.086 0.044
ATRN N/A 0.086 0.044
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.086 0.098
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.083 0.028
SELE SELE, ELAM1: E-selectin precursor 0.081 0.081
VNN2 VNN2: Vascular non-inflammatory molecule 2 precursor 0.081 0.063
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.079 0.051
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.073 0.029
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.073 0.026
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.073 0.033
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.072 0.065
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.072 0.032
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.071 0.027
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.071 0.072
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.069 0.029
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.0688 0.034
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.064 0.067
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.064 0.029
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.064 0.033
LDLR LDLR: Low-density lipoprotein receptor precursor 0.064 0.064
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.064 0.051
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.064 0.113
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.064 0.148
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.064 0.073
MEP1A MEP1A: Meprin A subunit alpha precursor 0.064 0.064
CSPG4 CSPG4, MCSP: Chondroitin sulfate proteoglycan 4 precursor 0.064 0.029
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.064 0.166
EGF EGF: Pro-epidermal growth factor precursor 0.063 0.081
AREG AREG, SDGF: Amphiregulin precursor 0.063 0.032
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.063 0.081
SORL1 SORL1: Sortilin-related receptor precursor 0.063 0.126
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.063 0.124
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.063 0.027
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.063 0.274
ITGB4 N/A 0.063 0.032
TLR4 TLR4: Toll-like receptor 4 precursor 0.058 0.036
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.058 0.026
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.058 0.032
ITGB7 ITGB7: Integrin beta-7 precursor 0.058 0.033
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.057 0.202
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.057 0.0446
CD44 N/A 0.057 0.036
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.056 0.246
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.056 0.029
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.056 0.046
DSP DSP: Desmoplakin 0.052 0.028
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.052 0.0446
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.052 0.0446
C5AR1 C5AR1, C5AR, C5R1: C5a anaphylatoxin chemotactic receptor 0.052 0.0446
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.051 0.031
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.051 0.040
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.051 0.111
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.0462 0.0446
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.044 0.029
XRCC1 XRCC1: DNA-repair protein XRCC1 0.041 0.039
CIC CIC, KIAA0306: Protein capicua homolog 0.039 0.026
CANX CANX: Calnexin precursor 0.037 0.028
FPR1 FPR1: fMet-Leu-Phe receptor 0.029 0.0446
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.029 0.036
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.029 0.032
LNX1 N/A 0.028 0.028
TUBGCP6 TUBGCP6, GCP6, KIAA1669: Gamma-tubulin complex component 6 0.028 0.028
PCGF6 N/A 0.028 0.028
CGN N/A 0.028 0.028
IRF2BP2 IRF2BP2, RP4-781K5.1-002: Interferon regulatory factor 2-binding protein 2. 0.028 0.028
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.028 0.083
MMRN1 MMRN1, ECM, EMILIN4, MMRN: Multimerin-1 precursor 0.027 0.051
LTBP1 LTBP1: Latent-transforming growth factor beta-binding protein, isoform 1S precur 0.027 0.051
CSPG5 N/A 0.027 0.051
PLAU PLAU: Urokinase-type plasminogen activator precursor 0.027 0.051
COL1A2 COL1A2: Collagen alpha-2(I) chain precursor 0.027 0.029
COL5A2 COL5A2: Collagen alpha-2(V) chain precursor 0.027 0.029
ELTD1 ELTD1, RP11-143H12.1-002: EGF, latrophilin and seven transmembrane domain contai 0.027 0.051
CLEC14A CLEC14A, C14orf27, UNQ236/PRO269, EGFR5: C-type lectin domain family 14 member A 0.027 0.027
CSPG3 CSPG3, NCAN, NEUR: Neurocan core protein precursor 0.027 0.027
LAMC2 LAMC2, LAMB2T, LAMNB2: Laminin subunit gamma-2 precursor 0.027 0.027
SCARF2 SCARF2, SREC2, SREPCR: Scavenger receptor class F member 2 precursor 0.027 0.027
NETO1 N/A 0.027 0.027
CFC1 CFC1: Cryptic protein precursor 0.027 0.027
MASP2 MASP2: Mannan-binding lectin serine protease 2 precursor 0.027 0.027
MUC13 MUC13, DRCC1, UNQ6194/PRO20221, RECC: Mucin-13 precursor 0.027 0.027
CCL28 CCL28, SCYA28: Small-inducible cytokine A28 precursor 0.027 0.027
XCL2 XCL2, SCYC2: Cytokine SCM-1 beta precursor 0.027 0.027
NTNG2 N/A 0.027 0.027
HHIP HHIP, HIP, UNQ5825/PRO19644: Hedgehog-interacting protein precursor 0.027 0.027
NELL2 NELL2, NRP2: Protein kinase C-binding protein NELL2 precursor 0.027 0.027
CXCL16 CXCL16, SCYB16, UNQ2759/PRO6714, SRPSOX: Small-inducible cytokine B16 precursor 0.027 0.027
PLSCR1 PLSCR1: Phospholipid scramblase 1 0.026 0.040
UNC5D N/A 0.025 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.025
SCRIB N/A 0.025 0.025
0.572
Total Score 26.60