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Evidence of Interaction Between PTPN1 and NCK1

The interaction score between PTPN1 and NCK1 is 20.6.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between PTPN1 and NCK1 = 0.37

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 3.80E-3
Orthology
OrganismPTPN1 OrthologueNCK1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
fly Q9W0G1 1 Q9VPU1 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.22E-3
Domains Domains present in PTPN1 and NCK1:
Domains in PTPN1Domains in NCK1
IPR000242 Tyrosine specific protein phosphatase
IPR000387 Tyrosine specific protein phosphatase and dual specificity protein phosphatase
IPR003595 Protein tyrosine phosphatase, catalytic region
IPR002035 von Willebrand factor, type A
IPR012265 Tyr_Ptase_nr1_2.
IPR001452 SH3
IPR000108 Neutrophil cytosol factor 2
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in PTPN1 and NCK1 are listed below.

Domain 1Domain 2Chi Square
IPR000242 Tyrosine specific protein phosphatase IPR000980 SH2 motif 17.0624
IPR002035 von Willebrand factor, type A IPR000980 SH2 motif 8.67735
IPR000387 Tyrosine specific protein phosphatase and dual specificity protein phosphatase IPR000980 SH2 motif 8.21089
IPR000242 Tyrosine specific protein phosphatase IPR001452 SH3 6.02157
IPR003595 Protein tyrosine phosphatase, catalytic region IPR001452 SH3 5.9163
IPR000387 Tyrosine specific protein phosphatase and dual specificity protein phosphatase IPR001452 SH3 3.6459
IPR012265 Tyr_Ptase_nr1_2. IPR000980 SH2 motif 3.11373
IPR003595 Protein tyrosine phosphatase, catalytic region IPR000980 SH2 motif 0.240348
IPR000242 Tyrosine specific protein phosphatase IPR000108 Neutrophil cytosol factor 2 0.162262
IPR000387 Tyrosine specific protein phosphatase and dual specificity protein phosphatase IPR000108 Neutrophil cytosol factor 2 0.00223994

The background colour of the table refers to:

  • Blue Domain is only present in PTPN1
  • Yellow Domain is only present in NCK1
  • Green Domain is present in both PTPN1 and NCK1

 0.109
Post-translational Modifications

Protein: PTPN1

PTMResidueReference
Acetylation 1 PubMed, HPRD
Glutathionylation 215 PubMed, HPRD
N-acetylmethionine 1 HPRD
Phosphorylation 50 PubMed, HPRD
Phosphorylation 66 PubMed, HPRD
Phosphorylation 152 PubMed, HPRD
Phosphorylation 153 PubMed, HPRD
Phosphorylation 242 PubMed, HPRD
Phosphorylation 243 PubMed, HPRD
Phosphorylation 352 PubMed, HPRD
Phosphorylation 378 PubMed, HPRD
Phosphorylation 386 PubMed, HPRD
Phosphoserine 50 PubMed, HPRD
Phosphoserine 352 HPRD
Phosphoserine 378 PubMed, HPRD
Phosphoserine 386 PubMed, HPRD
Phosphotyrosine 20 HPRD

Protein: NCK1

PTMResidueReference
Phosphorylation 85 PubMed, HPRD
Localisation

Protein: PTPN1

LocalisationReference
ER HPRD
Nucleus HPRD
Cytoplasm HPRD

Protein: NCK1

LocalisationReference
ER HPRD
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PTPN1 and NCK1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PTPN1 andNCK1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PTPN1 has 1180 interactors and NCK1 has 1601 interactors of which there are 818 common interactors.

Common InteractorName of Common InteractorScore for PTPN1-Interactor (?)Score for NCK1-Interactor (?)
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.515 0.126
VIL2 N/A 0.503 0.225
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.416 0.561
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.416 0.166
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.416 0.166
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.416 0.202
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.416 0.126
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.307 0.561
ITGAE ITGAE: Integrin alpha-E precursor 0.307 0.036
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.307 0.274
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.307 0.561
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.307 0.100
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.307 0.561
CRLF3 N/A 0.307 0.340
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.307 0.081
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.307 0.166
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.304 0.461
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.274 0.416
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.251 0.340
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.251 0.274
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.251 0.126
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.251 0.561
CXorf9 N/A 0.246 0.763
CSK CSK: Tyrosine-protein kinase CSK 0.246 6.03
VAV1 VAV1, VAV: Proto-oncogene vav 0.246 0.763
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.225 0.090
CD69 CD69: Early activation antigen CD69 0.210 0.0446
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.210 0.100
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.202 0.416
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.202 0.251
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.202 0.251
LYN LYN: Tyrosine-protein kinase Lyn 0.202 2.94
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.202 0.515
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.202 0.515
CD7 CD7: T-cell antigen CD7 precursor 0.191 0.340
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.191 0.126
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.191 0.202
GPA33 GPA33: Cell surface A33 antigen precursor 0.191 0.100
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.191 0.065
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.191 0.202
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.191 0.074
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.191 0.166
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.191 0.100
IL9R IL9R: Interleukin-9 receptor precursor 0.191 0.072
SORL1 SORL1: Sortilin-related receptor precursor 0.191 0.246
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.191 0.072
STAT6 STAT6: Signal transducer and activator of transcription 6 0.181 0.461
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.181 0.225
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.181 0.372
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.181 0.461
NCK2 NCK2: Cytoplasmic protein NCK2 0.181 0.275
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.181 0.461
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.171 0.577
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.166 0.225
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.166 0.515
ROCK1 ROCK1: Rho-associated protein kinase 1 0.166 0.515
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.166 0.307
FUBP1 N/A 0.166 0.430
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.166 3.28
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.166 0.251
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
EDA N/A 0.165 0.049
FN1 N/A 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.165 0.148
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.098
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
KIR3DL1 N/A 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.155 0.036
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.152 0.072
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.152 0.808
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.152 0.072
LILRB1 N/A 0.152 0.166
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.152 0.274
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.152 0.148
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.152 0.166
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.152 0.072
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.152 0.126
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.152 0.065
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.152 0.0727
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.152 0.808
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.152 0.126
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.152 0.100
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.148 0.372
JAK1 0.148 6.03
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.148 0.770
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.148 0.192
MSN MSN: Moesin 0.148 0.763
ATM ATM: Serine-protein kinase ATM 0.148 0.461
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.148 0.763
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.148 0.461
SYK SYK: Tyrosine-protein kinase SYK 0.148 2.17
STK10 STK10: Uncharacterized protein STK10 0.148 0.763
RPS6KB1 N/A 0.148 0.461
APS SH2B2, APS: SH2B adapter protein 2 0.148 0.136
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.148 3.64
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.148 0.275
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.148 2.17
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.098
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.148 0.098
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.878
BSG N/A 0.148 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.878
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.878
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.098
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.148 0.878
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.098
ATRN N/A 0.148 0.044
ITGB7 ITGB7: Integrin beta-7 precursor 0.139 0.066
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.136 0.586
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.136 0.058
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.136 0.461
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.136 0.586
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.136 0.275
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.136 0.655
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.136 0.655
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.136 0.090
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.136 0.520
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.136 0.655
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.136 0.275
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.130 0.0554
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.127 0.340
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.126 0.372
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.126 0.416
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.126 0.123
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.126 0.307
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.126 1.20
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.126 2.17
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.126 0.461
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.126 0.251
STK16 N/A 0.126 0.251
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.126 0.372
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.126 0.307
PRKAA1 N/A 0.126 0.251
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.126 0.136
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.126 0.859
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.126 0.416
GHR GHR: Growth hormone receptor precursor 0.123 0.081
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.123 0.058
PVR PVR, PVS: Poliovirus receptor precursor 0.123 0.0727
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.123 250.00
ITGB4 N/A 0.123 0.081
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.123 0.126
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.123 0.065
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.123 0.081
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.123 0.100
MET MET: Hepatocyte growth factor receptor precursor 0.123 0.644
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.123 0.065
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.123 0.0727
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.123 0.274
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.123 0.654
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.123 0.520
PRLR PRLR: Prolactin receptor precursor 0.123 0.065
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.114 0.503
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.114 0.246
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.113 0.136
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.113 0.225
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.113 0.461
CDK2 CDK2: Cell division protein kinase 2 0.113 0.225
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.113 0.225
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.113 0.461
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.113 0.275
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.113 2.94
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.113 3.64
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.113 0.461
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.113 0.372
CRKL CRKL: Crk-like protein 0.113 0.275
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.113 0.275
DAB2 DAB2, DOC2: Disabled homolog 2 0.113 0.097
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.113 0.275
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.113 0.763
TLN1 TLN1: Uncharacterized protein TLN1 0.113 0.225
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.113 0.136
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.113 0.372
DOK1 DOK1: Docking protein 1 0.113 0.225
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.111 0.078
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.111 0.146
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.110 0.577
DCC DCC: Netrin receptor DCC precursor 0.110 0.064
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.110 0.520
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.110 0.520
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.110 0.064
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.110 0.058
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.110 0.058
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.110 0.520
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.110 0.065
KIT KIT: Mast/stem cell growth factor receptor precursor 0.110 0.808
EPOR EPOR: Erythropoietin receptor precursor 0.110 0.072
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.110 0.065
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.109 0.165
MAP2K5 N/A 0.109 0.165
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 1.17
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.109 0.165
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.109 0.165
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.148
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.109 0.028
MAPK15 N/A 0.109 0.165
PKP4 PKP4: Plakophilin-4 0.109 0.028
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.109 0.056
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.109 0.028
STAT3 0.109 0.148
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 1.30
MAPKAPK5 N/A 0.109 0.165
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.165
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.109 0.165
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.109 0.148
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.109 0.148
CDC2 CDC2: Cell division control protein 2 homolog 0.109 0.148
NF2 NF2, SCH: Merlin 0.109 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.109 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.109 0.148
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.109 0.165
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.148
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.109 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.109 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 1.30
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.109 0.165
EEF2K EEF2K: Elongation factor 2 kinase 0.109 0.148
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.109 0.100
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.109 0.100
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.100 1.20
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.100 0.097
LIMK2 LIMK2: LIM domain kinase 2 0.100 0.191
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.100 0.136
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.100 1.20
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.100 0.110
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.100 0.043
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.100 0.063
DAPK2 DAPK2: Death-associated protein kinase 2 0.100 0.109
HCK N/A 0.100 1.78
IRS1 IRS1: Insulin receptor substrate 1 0.100 0.109
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.100 0.123
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.100 0.307
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.099 0.058
PTPRZ1 N/A 0.099 0.058
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.099 0.465
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.098 0.072
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.098 0.520
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.098 0.058
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.098 0.065
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.098 0.519
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.098 0.148
COTL1 COTL1, CLP: Coactosin-like protein 0.098 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.098 0.148
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.484
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.098 1.17
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.098 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.098 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.098 0.148
CFL2 CFL2: Cofilin-2 0.098 0.025
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.098 0.148
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.098 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.17
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.098 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.098 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.098 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.098 0.148
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.098 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.090
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.097 0.586
NEO1 NEO1, NGN: Neogenin precursor 0.097 0.065
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.097 0.064
TNC TNC, HXB: Tenascin precursor 0.097 0.073
INSR INSR: Insulin receptor precursor 0.097 0.586
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.096 0.202
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.096 0.191
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.096 0.166
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.094 0.246
SOS1 SOS1: Son of sevenless homolog 1 0.094 0.304
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.094 0.304
CDK4 CDK4: Cell division protein kinase 4 0.090 0.225
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.090 0.171
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.090 0.225
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.090 0.099
WEE1 WEE1: Wee1-like protein kinase 0.090 0.171
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.090 0.171
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 0.097
CFL1 CFL1, CFL: Cofilin-1 0.090 0.029
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.090 0.046
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.090 0.136
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.090 0.372
CDK7 CDK7, MO15: Cell division protein kinase 7 0.090 0.275
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.090 0.171
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.090 0.041
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.090 0.372
ALK ALK: ALK tyrosine kinase receptor precursor 0.090 0.361
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.090 0.099
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.090 0.372
VWF VWF, F8VWF: von Willebrand factor precursor 0.090 0.041
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.088 0.520
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.088 0.136
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.088 0.064
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.088 0.099
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.088 0.058
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.087 0.166
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.087 0.274
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.086 0.040
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.086 0.246
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.086 0.053
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.083 0.109
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.083 0.098
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.083 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.083 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.083 0.109
B2M B2M, CDABP0092, HDCMA22P: Beta-2-microglobulin precursor [Contains: Beta-2-micro 0.082 0.076
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.0818 40.60
FNBP1 N/A 0.0818 21.70
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.0818 24.50
AIP AIP, XAP2: AH receptor-interacting protein 0.0818 0.038
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.081 0.109
BMX N/A 0.081 0.775
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.081 0.251
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.081 0.099
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.081 0.251
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.081 0.132
CDKL5 N/A 0.081 0.098
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.081 0.225
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.081 0.041
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.081 0.136
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.081 0.045
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.081 0.152
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.081 0.975
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.081 0.123
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.081 0.152
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.081 0.251
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.081 0.191
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.081 0.099
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.081 0.109
STAT2 STAT2: Signal transducer and activator of transcription 2 0.0794 0.166
STAT4 STAT4: Signal transducer and activator of transcription 4 0.0794 0.246
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.0794 0.561
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.077 0.027
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.075 0.136
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.075 0.191
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.075 0.251
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.075 0.098
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.075 0.044
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.075 0.098
CIITA CIITA, MHC2TA: MHC class II transactivator 0.074 0.0425
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.073 2.17
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.073 0.041
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.073 1.07
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.073 0.088
TTN N/A 0.073 0.097
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.073 0.372
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.073 0.041
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.073 0.110
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.073 0.171
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.073 0.225
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.073 0.275
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.073 0.078
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.073 0.225
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.073 0.225
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.073 0.029
RAB32 RAB32: Ras-related protein Rab-32 0.073 0.046
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.073 0.136
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.073 0.171
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.073 0.088
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.073 0.099
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.0727 0.099
DBN1 DBN1, D0S117E: Drebrin 0.072 0.026
RIN1 RIN1: Ras and Rab interactor 1 0.072 0.136
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.072 0.045
CSPG2 N/A 0.072 0.063
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.072 0.152
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.072 0.046
IRS2 IRS2: Insulin receptor substrate 2 0.072 0.123
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.072 0.088
VDP DKFZp451D234: Putative uncharacterized protein DKFZp451D234 0.071 0.040
HLA-DRA 0.070 0.027
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.098
HLA-DPA1 HLA-DPA1, HLA-DP1A, HLASB: HLA class II histocompatibility antigen, DP alpha cha 0.067 0.039
HLA-DRB5 HLA-DRB3: HLA class II histocompatibility antigen, DRB3-1 beta chain precursor 0.067 0.032
HLA-DQA1 HLA-DQA1: HLA class II histocompatibility antigen, DQ(5) alpha chain precursor 0.067 0.032
IL2RG IL2RG: Cytokine receptor common gamma chain precursor 0.067 0.108
HLA-E HLA-E, XXbac-BPG34K20.2-001: MHC class Ib antigen 0.067 0.108
HLA-DRB5 HLA-Dw12: Cell surface glycoprotein 0.067 0.032
KIAA1012 KIAA1012: Protein TRS85 homolog 0.067 0.129
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.067 0.461
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.067 0.461
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.067 0.129
LCP1 LCP1, PLS2: Plastin-2 0.067 0.241
C20orf4 C20orf4, CGI-23, PRO0225: Uncharacterized protein C20orf4 0.067 0.029
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.067 0.275
PSCD4 PSCD4, CYT4: Cytohesin-4 0.067 0.372
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.067 0.385
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.067 0.276
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.067 0.241
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.067 0.078
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.067 0.078
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.067 0.372
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.099
CDK5 CDK5: Cell division protein kinase 5 0.065 0.110
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.065 0.694
TLN2 TLN2: Uncharacterized protein TLN2 0.065 0.070
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.065 0.136
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.078
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.065 0.099
RDX RDX: Radixin 0.065 0.097
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.065 1.07
CDK6 CDK6: Cell division protein kinase 6 0.064 0.136
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.064 0.088
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.064 0.110
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.064 0.041
MYO3A MYO3A: Myosin IIIA 0.064 0.099
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.064 0.136
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.064 0.088
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.064 0.097
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.064 0.225
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.064 0.225
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.064 0.136
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.064 0.088
DAB1 DAB1: Disabled homolog 1 0.064 0.088
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.064 0.037
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.063 0.166
EGF EGF: Pro-epidermal growth factor precursor 0.062 0.072
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.062 0.098
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.062 0.098
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.062 0.098
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.062 0.098
MVP MVP, LRP: Major vault protein 0.061 0.070
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.061 0.070
PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 0.061 0.026
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.061 0.385
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 0.060 0.074
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.059 0.0955
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.059 0.0782
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.058 0.088
DYRK3 N/A 0.058 0.097
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.058 0.136
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.058 0.136
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.058 0.099
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.058 0.099
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.058 0.770
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.058 0.037
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.058 0.097
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.058 0.097
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.058 0.088
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.058 0.088
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.057 0.181
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.057 0.307
CD2AP CD2AP: CD2-associated protein 0.057 0.372
FLNA FLNA, FLN, FLN1: Filamin-A 0.057 0.070
VASP VASP: Vasodilator-stimulated phosphoprotein 0.057 0.307
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.057 0.060
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.057 0.515
HD HD, IT15: Huntingtin 0.057 0.155
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.056 0.029
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.056 0.033
MEP1B MEP1B: Meprin A subunit beta precursor 0.056 0.029
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.056 0.033
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.056 0.0727
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.055 0.0453
F3 F3: Tissue factor precursor 0.055 0.081
FLII FLII, FLIL: Protein flightless-1 homolog 0.054 0.087
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.054 0.029
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.054 0.078
MYLIP MYLIP, BZF1, BM-023, PP5242: E3 ubiquitin-protein ligase MYLIP 0.053 0.050
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.052 0.043
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.052 0.088
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
GSK3B GSK3B: Glycogen synthase kinase-3 beta 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
MARK2 N/A 0.051 0.051
NCAM1 N/A 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
GRB10 N/A 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
MAPK11 MAPK11, PRKM11, SAPK2: Mitogen-activated protein kinase 11 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
MAP4K4 N/A 0.051 0.051
IGHM N/A 0.051 0.051
PRKCD PRKCD: Protein kinase C delta type 0.051 0.051
IGHG3 N/A 0.051 0.051
IGHD N/A 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
TLK2 TLK2: Serine/threonine-protein kinase tousled-like 2 0.051 0.046
DOK2 DOK2: Docking protein 2 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
CHUK CHUK, IKKA, TCF16: Inhibitor of nuclear factor kappa-B kinase subunit alpha 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
HLA-A N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
MAPK7 MAPK7, ERK4, ERK5, PRKM7: Mitogen-activated protein kinase 7 0.051 0.046
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
IGHG1 N/A 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.051 0.081
ETS2 ETS2: Protein C-ets-2 0.051 0.100
PLEK PLEK, P47: Pleckstrin 0.0513 0.340
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.051 0.078
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.051 0.063
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.051 0.078
ACTG1 ACTB: Actin, cytoplasmic 1 0.051 0.233
RASA3 RASA3: Ras GTPase-activating protein 3 0.051 0.372
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.051 0.461
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.051 0.461
PLD1 PLD1: Phospholipase D1 0.051 0.136
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.051 0.038
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.051 0.372
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.051 5.88
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.051 0.461
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.050 0.029
NCR3 NCR3, 1C7, LY117: Natural cytotoxicity triggering receptor 3 precursor 0.050 0.065
TAPBPL TAPBPL: Tapasin-related protein precursor 0.050 0.065
BFAR BFAR, BAR, RNF47: Bifunctional apoptosis regulator 0.050 0.053
IL21R IL21R, NILR, UNQ3121/PRO10273: Interleukin-21 receptor precursor 0.050 0.039
HLA-F HLA-F, HLA-5.4, HLAF: HLA class I histocompatibility antigen, alpha chain F prec 0.050 0.108
IL27RA N/A 0.050 0.065
DNM3 DNM3: Uncharacterized protein DNM3 0.049 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.049 0.165
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.049 0.148
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.049 0.047
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.049 0.052
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.049 0.148
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.049 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.049 0.165
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.049 0.148
PSCD2 N/A 0.049 0.165
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.049 0.148
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.049 0.165
PPEF1 N/A 0.049 0.052
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.052
NASP NASP: Nuclear autoantigenic sperm protein 0.049 0.028
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.049 0.026
TNFRSF1B TNFRSF1B, TNFBR, TNFR2: Tumor necrosis factor receptor superfamily member 1B pre 0.048 0.027
STK17A STK17A, DRAK1: Serine/threonine-protein kinase 17A 0.047 0.074
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.046 0.032
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.046 0.046
IKBKE IKBKE, IKKE, IKKI, KIAA0151: Inhibitor of nuclear factor kappa-B kinase subunit 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.553
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
SRPK1 SRPK1: Serine/threonine-protein kinase SRPK1 0.046 0.046
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.046 0.073
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.046 0.148
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.046 0.040
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.045 0.233
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.0453 0.372
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.0453 0.045
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.0453 0.045
MMP9 MMP9, CLG4B: Matrix metalloproteinase-9 precursor 0.0453 0.025
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.0453 0.052
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.0453 0.029
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.0453 0.060
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0453 0.0425
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.0453 0.0971
SCML2 SCML2: Sex comb on midleg-like protein 2 0.045 0.072
TP73 TP73, P73: Tumor protein p73 0.045 0.072
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.044 0.026
MEP1A MEP1A: Meprin A subunit alpha precursor 0.044 0.029
GRK7 GRK7, GPRK7: G protein-coupled receptor kinase 7 precursor 0.044 0.056
NIPBL N/A 0.044 0.025
BMP1 N/A 0.044 0.030
ELMO1 N/A 0.044 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.044 0.148
ARHGEF7 N/A 0.044 0.148
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.044 0.047
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.044 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.044 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.044 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.025
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.044 0.148
TSC2 TSC2, TSC4: Tuberin 0.044 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.044 0.047
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.044 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.044 0.047
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.044 0.148
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.043 0.029
CD44 N/A 0.0425 0.125
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.0425 0.111
CCR5 CCR5: CCR5 receptor (Fragment) 0.0425 0.202
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.042 0.070
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.041 0.372
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.041 0.064
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.041 0.275
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.041 2.22
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.041 0.046
CDC23 CDC23: Cell division cycle protein 23 homolog 0.041 0.063
PLD2 PLD2: Phospholipase D2 0.041 0.110
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.041 0.171
MDN1 MDN1, KIAA0301: Midasin 0.041 0.046
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.041 0.031
COPE COPE: Coatomer subunit epsilon 0.041 0.038
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.041 0.046
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.041 0.063
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.041 0.063
XPO1 XPO1, CRM1: Exportin-1 0.041 0.078
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.041 0.029
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.041 0.225
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.041 0.111
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.041 0.046
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.041 0.139
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.041 0.118
BTN3A3 BTN3A3, BTF3: Butyrophilin subfamily 3 member A3 precursor 0.041 0.108
BTN3A2 BTN3A2, BT3.2, BTF3, BTF4: Butyrophilin subfamily 3 member A2 precursor 0.041 0.108
IL10RB IL10RB, CRFB4, D21S58, D21S66: Interleukin-10 receptor beta chain precursor 0.041 0.039
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.04 0.025
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.04 0.028
CNN2 CNN2: Calponin-2 0.04 0.148
GNB2L1 Lung cancer oncogene 7 0.039 0.0446
GRAP GRAP: GRB2-related adapter protein 0.039 0.028
DYRK2 DYRK2: Dual specificity tyrosine-phosphorylation-regulated kinase 2 0.039 0.137
MAP4K2 MAP4K2, GCK, RAB8IP: Mitogen-activated protein kinase kinase kinase kinase 2 0.039 0.036
MICB MICB: MHC class I polypeptide-related sequence B (Fragment) 0.039 0.037
XRCC1 XRCC1: DNA-repair protein XRCC1 0.039 0.027
NBN NBN, NBS, NBS1, P95: Nibrin 0.039 0.0446
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.038 0.034
GNAI2 Galphai2 protein 0.038 0.032
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.037 0.046
IPO7 IPO7: Uncharacterized protein IPO7 0.037 0.0425
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.037 0.0308
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.037 0.045
GAB1 GAB1: GRB2-associated-binding protein 1 0.037 0.123
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.060
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.037 0.046
MMP13 MMP13: Collagenase 3 precursor 0.037 0.031
MCF2 MCF2, DBL: Proto-oncogene DBL 0.037 0.109
S100A7 S100A7, PSOR1: Protein S100-A7 0.037 0.039
LTK LTK, TYK1: Leukocyte tyrosine kinase receptor precursor 0.036 0.296
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.036 0.025
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.036 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.036 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.036 0.025
MYO18A 0.036 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.036 0.025
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.035 0.029
HPN HPN, TMPRSS1: Serine protease hepsin 0.035 0.029
VAV3 VAV3: Protein vav-3 0.035 0.036
ARAF ARAF, ARAF1, PKS, PKS2: A-Raf proto-oncogene serine/threonine-protein kinase 0.035 0.036
TNKS2 TNKS2, PARP5B, TANK2, TNKL: Tankyrase-2 0.035 0.0968
ARFGEF2 ARFGEF2, ARFGEP2, BIG2: Brefeldin A-inhibited guanine nucleotide-exchange protei 0.035 0.040
TNN TNN: Tenascin-N precursor 0.034 0.042
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0338 0.034
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.0338 0.0338
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.0338 0.047
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.033 0.029
STAM2 STAM2: Signal transducing adapter molecule 2 0.033 0.136
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.033 0.028
PRDX1 PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1 0.033 0.029
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.033 0.029
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.033 0.171
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.033 0.046
ACTN1 ACTN1: Alpha-actinin-1 0.033 0.043
MYL3 MYL3: Myosin light polypeptide 3 0.033 0.028
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.033 0.046
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.033 0.0308
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.033 0.035
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.033 0.029
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.033 0.139
SPTAN1 N/A 0.033 0.110
CTTN CTTN, EMS1: Src substrate cortactin 0.033 2.23
S100A3 S100A3, S100E: Protein S100-A3 0.032 0.031
GAB2 N/A 0.032 0.123
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.032 0.046
SORBS3 SORBS3, SCAM1: Vinexin 0.032 0.097
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.032 0.027
IL7R N/A 0.032 0.027
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.032 0.100
RPS10 RPS10: 40S ribosomal protein S10 0.032 0.078
CSNK1G3 CSNK1G3: Casein kinase I isoform gamma-3 0.032 0.083
IRAK4 IRAK4: Interleukin-1 receptor-associated kinase 4 0.032 0.074
SAMD9 SAMD9, C7orf5, DRIF1, KIAA2004, OEF1: Sterile alpha motif domain-containing prot 0.032 0.083
RIPK2 RIPK2, CARDIAK, UNQ277/PRO314/PRO34092, RICK, RIP2: Receptor-interacting serine/ 0.032 0.041
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.031 0.148
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.031 0.027
TSHR N/A 0.0308 0.033
IL18RAP IL18RAP: Interleukin-18 receptor accessory protein precursor 0.0308 0.065
RYK RYK, JTK5A: Tyrosine-protein kinase RYK precursor 0.0308 0.404
SEMA4D SEMA4D, CD100, SEMAJ: Semaphorin-4D precursor 0.0308 0.108
MICA MICA: MHC class I chain-related protein A 0.0308 0.053
IL18R1 IL18R1, IL1RRP: Interleukin-18 receptor 1 precursor 0.0308 0.053
CD226 CD226, DNAM1: CD226 antigen precursor 0.0308 0.032
ICOS ICOS, AILIM: Inducible T-cell co-stimulator precursor 0.0308 0.032
CD96 CD96: T-cell surface protein tactile precursor 0.0308 0.065
SLAMF7 SLAMF7, CS1, UNQ576/PRO1138: SLAM family member 7 precursor 0.0308 0.039
IFNGR2 IFNGT1, IFNGR2: Interferon-gamma receptor beta chain precursor 0.0308 0.032
KIR2DS3 KIR2DS3, NKAT7: Killer cell immunoglobulin-like receptor 2DS3 precursor 0.0308 0.032
CD86 CD86, CD28LG2: T-lymphocyte activation antigen CD86 precursor 0.0308 0.032
SIGIRR SIGIRR, UNQ301/PRO342: Single Ig IL-1-related receptor 0.0308 0.065
CD300A CD300A, CMRF35H: CMRF35-H antigen precursor 0.0308 0.065
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.030 0.036
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.030 0.098
CETN1 CETN1, CEN1, CETN: Centrin-1 0.030 0.036
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.030 0.0425
APBA3 APBA3, MINT3, X11L2: Amyloid beta A4 precursor protein-binding family A member 3 0.030 0.053
PSD TYL: TYL protein 0.029 0.097
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.029 0.028
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.099
DLG2 DLG2: Disks large homolog 2 0.029 0.033
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.029 0.109
S100B S100B: Protein S100-B 0.029 0.031
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.029 0.123
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.029 0.029
CHP CHP: Calcium-binding protein p22 0.029 0.043
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.029 0.038
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.029 0.029
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.029 0.078
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.029 0.066
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.029 0.032
CLK3 CLK3: Dual specificity protein kinase CLK3 0.029 0.036
ADRBK2 ADRBK2, BARK2, GRK3: Beta-adrenergic receptor kinase 2 0.029 0.036
CSNK1D CSNK1D: Casein kinase I isoform delta 0.029 0.060
PRKX PRKX, PKX1: Serine/threonine-protein kinase PRKX 0.029 0.123
CSNK1G2 CSNK1G2: Casein kinase I isoform gamma-2 0.029 0.123
TRIB2 TRIB2, TRB2: Tribbles homolog 2 0.029 0.060
PRKCH PRKCH, PKCL, PRKCL: Protein kinase C eta type 0.029 0.074
RP6-213H19.1 MST4, MASK: Serine/threonine-protein kinase MST4 0.029 0.263
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.049
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.109
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.109
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.028 0.049
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.028 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.028 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.109
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.028 0.109
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.028 0.036
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.028 0.040
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.027 0.038
TBCE TBCE: Tubulin-specific chaperone E 0.027 0.046
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.027 0.046
EIF2AK3 EIF2AK3, PEK, PERK: Eukaryotic translation initiation factor 2-alpha kinase 3 pr 0.027 0.027
FGFR2 N/A 0.027 0.217
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.265
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.027 0.195
WASPIP N/A 0.027 86.60
LPXN LPXN, LDLP: Leupaxin 0.027 0.129
DAPP1 N/A 0.027 0.052
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.027 0.087
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.027 0.087
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.027 0.087
IFI35 N/A 0.027 0.070
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.027 0.078
CNN3 CNN3: Calponin-3 0.0263 0.088
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.026 0.136
KLC2 KLC2: Kinesin light chain 2 0.026 0.031
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.026 0.028
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.035
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.026 0.0453
SDC1 SDC1, SDC: Syndecan-1 precursor 0.026 0.032
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.026 0.057
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.026 0.075
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.026 0.127
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.026 0.029
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.026 0.100
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.026 0.075
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.026 0.100
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.044
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.025 0.044
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.044
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.025 0.098
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.025 0.098
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.025 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.025 0.044
0.347
Total Score 20.6