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Evidence of Interaction Between CD2AP and CASP3

The interaction score between CD2AP and CASP3 is 5.74.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between CD2AP and CASP3 = 0.52

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 6.27E-3
Orthology
OrganismCD2AP OrthologueCASP3 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00477876 1 IPI00216675 0.146

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.22E-3
Domains No domains were used in calculating likelihood of interaction 0.028
Post-translational Modifications

Protein: CD2AP

PTMResidueReference
Phosphotyrosine 88 HPRD

Protein: CASP3

PTMResidueReference
Phosphorylation 26 PubMed, HPRD
Proteolytic Cleavage 9 PubMed, HPRD
Proteolytic Cleavage 175 PubMed, HPRD
Proteolytic Cleavage 179 PubMed, HPRD
Proteolytic Cleavage 253 PubMed, HPRD
S-Nitrosylation 163 PubMed, HPRD
Localisation

Protein: CD2AP

LocalisationReference
Plasma membrane HPRD
Nucleolus HPRD
Cytoplasm HPRD

Protein: CASP3

LocalisationReference
Cytosol HPRD
Mitochondrion HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between CD2AP and CASP3 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CD2AP andCASP3. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CD2AP has 1210 interactors and CASP3 has 906 interactors of which there are 617 common interactors.

Common InteractorName of Common InteractorScore for CD2AP-Interactor (?)Score for CASP3-Interactor (?)
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 72.80 0.029
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 20.60 0.046
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 6.64 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 6.64 0.025
PRKCB1 N/A 1.33 0.025
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.995 0.029
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.964 0.078
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.852 0.0425
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.763 0.063
NEDD4L N/A 0.593 1.07
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.515 0.052
SYK SYK: Tyrosine-protein kinase SYK 0.515 0.029
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.515 0.046
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.503 0.040
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.461 0.188
RPS6KB1 N/A 0.461 0.046
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.461 0.063
CSK CSK: Tyrosine-protein kinase CSK 0.461 0.046
FUBP1 N/A 0.430 0.070
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.416 0.032
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.416 0.038
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.385 0.063
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.385 0.063
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.372 0.038
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.046
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.372 0.038
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.372 0.038
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.029
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.372 0.046
CRKL CRKL: Crk-like protein 0.372 0.063
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.029
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.372 0.046
VAV1 VAV1, VAV: Proto-oncogene vav 0.372 0.038
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.372 0.029
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.340 0.036
PLEK PLEK, P47: Pleckstrin 0.340 0.027
JAK1 0.307 0.029
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.127
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.307 0.038
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.307 0.0425
MSN MSN: Moesin 0.275 0.038
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.275 0.029
WASPIP N/A 0.275 0.046
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.275 0.029
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.275 0.038
CXorf9 N/A 0.275 0.038
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.275 0.029
LYN LYN: Tyrosine-protein kinase Lyn 0.275 0.026
CENPA CENPA: Histone H3-like centromeric protein A 0.274 0.036
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.260 0.052
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.251 0.032
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.251 0.032
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.251 0.0425
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.251 0.032
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.251 0.251
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.233 0.139
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.233 0.046
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.038
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.233 0.046
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.233 0.046
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.233 0.046
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.233 0.114
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.233 0.046
FNBP1 N/A 0.233 0.046
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.225 0.038
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.225 0.114
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.225 0.038
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.225 0.046
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.225 0.029
VIL2 N/A 0.225 0.029
NCK2 NCK2: Cytoplasmic protein NCK2 0.225 0.029
DOK1 DOK1: Docking protein 1 0.225 0.038
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.210 0.038
PHB2 PHB2, BAP, REA: Prohibitin-2 0.210 0.070
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.210 0.070
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.210 0.052
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.191 0.032
VASP VASP: Vasodilator-stimulated phosphoprotein 0.191 0.032
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.191 0.0425
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.191 0.026
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.191 0.032
STK16 N/A 0.191 0.052
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.188 0.046
CDK2 CDK2: Cell division protein kinase 2 0.188 0.063
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.188 0.046
CDK4 CDK4: Cell division protein kinase 4 0.188 0.063
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.188 0.046
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.188 0.029
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.188 0.046
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.188 0.046
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.188 0.038
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.181 0.067
H2AFX H2AFX, H2AX: Histone H2A.x 0.181 0.032
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.171 0.029
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.029
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.171 0.029
PLD1 PLD1: Phospholipase D1 0.171 0.038
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.171 0.038
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.171 0.038
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.171 0.029
APS SH2B2, APS: SH2B adapter protein 2 0.171 0.029
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.028
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.028
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.028
NF2 NF2, SCH: Merlin 0.165 0.028
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.165 0.028
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.028
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.028
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.165 0.025
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.165 0.025
PSCD2 N/A 0.165 0.028
MAPK15 N/A 0.165 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.028
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.028
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.163 0.260
WEE1 WEE1: Wee1-like protein kinase 0.155 0.046
HD HD, IT15: Huntingtin 0.155 0.155
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.155 0.032
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.152 0.026
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.152 0.032
GAB2 N/A 0.152 0.026
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.152 0.026
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.025
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.075
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.025
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.148 0.025
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.025
STAT3 0.148 0.028
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.025
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.025
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.148 0.028
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.148 0.028
ARHGEF7 N/A 0.148 0.025
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 12.00
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.025
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.148 0.025
ELMO1 N/A 0.148 0.025
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.146 0.063
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.146 0.118
SRPR SRPR: Uncharacterized protein SRPR 0.144 0.0425
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.144 0.071
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.141 0.090
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.140 0.052
THOP1 THOP1: Thimet oligopeptidase 0.139 0.038
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.063
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.139 0.029
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.139 0.029
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.139 0.038
CDK7 CDK7, MO15: Cell division protein kinase 7 0.139 0.046
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.139 0.063
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.139 0.038
STK10 STK10: Uncharacterized protein STK10 0.139 0.029
ACTG1 ACTB: Actin, cytoplasmic 1 0.139 0.046
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.136 0.038
PLD2 PLD2: Phospholipase D2 0.136 0.038
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.129 0.078
QARS QARS: Glutaminyl-tRNA synthetase 0.129 0.063
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.129 0.146
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.129 0.063
XPO1 XPO1, CRM1: Exportin-1 0.129 0.146
HNRPK N/A 0.129 0.063
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.126 0.046
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.123 0.026
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.123 0.026
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.026
GAB1 GAB1: GRB2-associated-binding protein 1 0.123 0.026
SEC24B SEC24B: Protein transport protein Sec24B 0.118 0.063
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.114 0.046
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.114 22.30
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.114 0.029
TLN1 TLN1: Uncharacterized protein TLN1 0.114 0.046
ATM ATM: Serine-protein kinase ATM 0.114 0.029
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.046
LIG1 LIG1: DNA ligase 1 0.112 0.040
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.110 0.038
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.110 0.026
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.104 0.038
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.0971 0.052
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.032
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.096 0.026
PRKAA1 N/A 0.096 0.026
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.091 0.027
KIF23 N/A 0.091 0.027
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.090 0.029
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.088 0.049
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.087 0.032
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.087 0.087
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.070
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.087 0.070
PPARBP N/A 0.087 0.046
ABCF1 N/A 0.087 0.070
FLII FLII, FLIL: Protein flightless-1 homolog 0.087 0.114
HDLBP HDLBP, HBP, VGL: Vigilin 0.086 0.038
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.086 0.029
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.083 0.028
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.083 0.025
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.083 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.083
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.0818 0.032
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.0818 0.032
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.081 0.0453
RPL8 RPL8: 60S ribosomal protein L8 0.078 0.063
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.078 0.063
VCP VCP: Transitional endoplasmic reticulum ATPase 0.078 0.063
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.078 0.063
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.078 0.063
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.078 0.063
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.078 0.052
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.078 0.078
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.078 0.046
COPA COPA: Coatomer subunit alpha 0.078 0.046
CDC23 CDC23: Cell division cycle protein 23 homolog 0.078 0.146
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.038
LDHB LDHB: L-lactate dehydrogenase B chain 0.078 0.078
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.078 0.063
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.078 0.078
CTPS CTPS: CTP synthase 1 0.078 0.063
LPXN LPXN, LDLP: Leupaxin 0.078 0.046
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.078 0.063
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.046
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.078 0.063
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.078 0.063
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.078 0.046
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.078 0.078
NRAS NRAS, HRAS1: GTPase NRas precursor 0.078 0.046
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.078 0.063
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.078 0.063
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.087
CCT8 CCT8: Uncharacterized protein CCT8 0.078 0.063
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.078 0.078
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.078 0.063
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.078 0.063
RPS10 RPS10: 40S ribosomal protein S10 0.078 0.275
CDK6 CDK6: Cell division protein kinase 6 0.077 0.029
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.062
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.076 18.30
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.025
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.075 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.075 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.075 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.025
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.025
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.025
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.025
EEF2K EEF2K: Elongation factor 2 kinase 0.075 0.028
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.028
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.074 0.032
NBN NBN, NBS, NBS1, P95: Nibrin 0.074 0.124
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.074 0.0446
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.074 0.036
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.074 0.036
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.074 0.032
DDX21 DDX21: Nucleolar RNA helicase 2 0.074 0.027
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.074 0.032
DNM2 N/A 0.070 0.0425
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.052
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.070 0.052
TRRAP N/A 0.070 0.070
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.070 0.155
CHUK N/A 0.070 0.052
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.070 0.155
ESPL1 N/A 0.070 0.052
API5 N/A 0.070 0.070
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.069 0.029
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.069 0.152
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.067 0.032
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.066 0.032
NUP153 N/A 0.066 0.032
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.066 0.032
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.066 0.032
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.066 0.040
TIAL1 TIAL1: Nucleolysin TIAR 0.066 0.040
VDP DKFZp451D234: Putative uncharacterized protein DKFZp451D234 0.066 0.090
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.066 0.032
CBX3 CBX3: Chromobox protein homolog 3 0.066 0.040
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.066 0.032
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.066 0.032
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.066 0.032
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.066 0.032
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.066 0.040
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.066 0.032
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.066 0.032
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.066 0.032
SSB SSB: Lupus La protein 0.066 0.040
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.066 0.032
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.066 0.032
TPT1 TPT1: Translationally-controlled tumor protein 0.063 0.038
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.063 0.046
MDN1 MDN1, KIAA0301: Midasin 0.063 0.063
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.038
THOC1 THOC1, HPR1: THO complex subunit 1 0.063 0.275
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.063 0.038
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.063 0.063
LCP1 LCP1, PLS2: Plastin-2 0.063 0.038
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.063 0.046
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.139
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.063 0.275
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.063 0.046
HSP90AA1 Hsp89-alpha-delta-N 0.063 0.046
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.063 0.114
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.063 0.046
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.063 0.046
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.063 0.046
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.063 0.046
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.063 0.063
KLHDC4 N/A 0.063 0.038
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.063 0.046
HSPD1 0.063 0.063
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.063 0.038
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.063 0.046
EEF2 EEF2, EF2: Elongation factor 2 0.063 0.063
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.063 0.052
PTPN11 N/A 0.063 0.063
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.063 0.046
GRLF1 N/A 0.062 0.026
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.062 0.096
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.056 0.028
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.056 0.025
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.056 0.029
SPTAN1 N/A 0.056 0.062
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.055 0.026
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.054 0.0425
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.052 0.070
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.052 0.032
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.052 0.026
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.052 0.052
MPG N/A 0.052 0.052
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.0425
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.052 0.046
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.070
CIITA CIITA, MHC2TA: MHC class II transactivator 0.052 0.251
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.307
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.052 0.0425
UBAP2 N/A 0.052 0.070
IPO7 IPO7: Uncharacterized protein IPO7 0.052 0.087
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.052 0.307
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.051 0.027
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.050 0.083
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.049 0.029
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.049 0.032
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.047 0.025
GSN GSN: Gelsolin precursor 0.047 0.025
SVIL SVIL: Supervillin 0.047 0.025
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.046 0.071
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.046 0.063
GPI GPI: Glucose-6-phosphate isomerase 0.046 0.046
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.046 0.029
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.046 0.046
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.046 0.046
TRIP13 TRIP13: Thyroid receptor-interacting protein 13 0.046 0.046
SYMPK SYMPK, SPK: Symplekin 0.046 0.071
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.029
SAPS3 N/A 0.046 0.046
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.046 0.052
RACGAP1 RACGAP1, KIAA1478, MGCRACGAP: Rac GTPase-activating protein 1 0.046 0.046
GSK3B N/A 0.046 0.029
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.046 0.038
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.046 0.046
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.046 0.038
RP2 RP2: Protein XRP2 0.046 0.032
TK1 TK1: Thymidine kinase, cytosolic 0.046 0.052
EXOC2 N/A 0.046 0.029
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.046 0.063
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.038
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.046 0.078
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.046 0.114
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.046 0.029
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0446 0.027
ELF1 ELF1: ETS-related transcription factor Elf-1 0.0446 0.027
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.0446 0.036
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.0446 0.036
SET SET: Protein SET 0.0446 0.0446
TOP2B N/A 0.0446 0.0446
RBM14 RBM14, SIP: RNA-binding protein 14 0.0446 0.027
MATR3 MATR3, KIAA0723: Matrin-3 0.0446 0.036
PTMA N/A 0.0446 0.036
NPM1 NPM1, NPM: Nucleophosmin 0.0446 0.032
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.0446 0.036
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.0446 0.027
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.0446 0.032
IFI16 N/A 0.0446 0.027
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0446 0.027
GNB2L1 Lung cancer oncogene 7 0.0446 0.036
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.0446 0.153
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.0425 0.096
MVP MVP, LRP: Major vault protein 0.0425 0.026
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.0425 0.0425
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.026
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.0425 0.071
MARK2 N/A 0.0425 0.026
DAPP1 N/A 0.0425 0.032
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.0425 0.038
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.032
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.0425 0.032
LIG4 LIG4: DNA ligase 4 0.041 0.041
HDAC2 HDAC2: Histone deacetylase 2 0.040 0.032
PPP1R8 N/A 0.040 0.032
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.040 0.040
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.040 0.032
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.040 0.040
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.040 0.246
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.040 0.032
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.040 0.032
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.040 0.032
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.040 0.032
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.040 0.032
MCM3 MCM3: DNA replication licensing factor MCM3 0.040 0.032
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.040 0.032
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.040 0.032
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.040 0.196
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.040 0.040
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.040 0.040
YY1 YY1: Transcriptional repressor protein YY1 0.040 0.032
ARFGEF2 ARFGEF2, ARFGEP2, BIG2: Brefeldin A-inhibited guanine nucleotide-exchange protei 0.040 0.067
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.040 0.111
TP53 TP53, P53: Cellular tumor antigen p53 0.040 0.032
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.040 0.032
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.040 0.032
WBSCR20A N/A 0.040 0.032
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.040 0.032
POLA2 POLA2: DNA polymerase subunit alpha B 0.040 0.032
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.040 0.040
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.040 0.032
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.040 0.111
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.038 0.029
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.038 0.038
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.046
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.038 0.029
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.038 0.063
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.029
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.038 0.0425
PRDX1 PRDX1, PAGA, PAGB, TDPX2: Peroxiredoxin-1 0.038 0.046
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.038 0.046
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.038 0.038
MDH2 MDH2: Malate dehydrogenase, mitochondrial precursor 0.038 0.046
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.038 0.046
AIP AIP, XAP2: AH receptor-interacting protein 0.038 0.114
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.038 0.038
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.038 0.029
RIN1 RIN1: Ras and Rab interactor 1 0.037 0.029
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.037 0.046
DNMT1 DNMT1, AIM, DNMT: DNA 0.036 0.0446
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.036 0.027
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.036 0.036
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.036 0.0446
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.036 0.027
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.036 0.036
MKI67 MKI67: Antigen KI-67 0.036 0.036
WDR1 N/A 0.036 0.027
ARFGAP1 N/A 0.036 0.036
ZNF267 ZNF267: Zinc finger protein 267 0.036 0.027
TCOF1 N/A 0.036 0.036
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.036 0.040
KIAA0853 N/A 0.036 0.027
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.036 0.036
IRF3 IRF3: Interferon regulatory factor 3 0.036 0.027
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.036 0.036
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.036 0.027
RB1 RB1: Retinoblastoma-associated protein 0.036 0.124
MCF2 MCF2, DBL: Proto-oncogene DBL 0.033 0.055
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.032 0.038
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.026
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.032 0.032
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.032 0.032
FLNA FLNA, FLN, FLN1: Filamin-A 0.032 0.032
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.032 0.029
SAT SAT1, SAT: Diamine acetyltransferase 1 0.032 0.026
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.032 0.038
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.032 0.026
PCNA PCNA: Proliferating cell nuclear antigen 0.032 0.032
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.032 0.027
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.032 0.124
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.032 0.040
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.032 0.032
UNG N/A 0.032 0.036
SRF SRF: Serum response factor 0.032 0.0818
KIF11 N/A 0.032 0.032
WBSCR1 EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H 0.032 0.040
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.032 0.051
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.032 0.032
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.032 0.032
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.032 0.091
MAD2L1 MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A 0.032 0.032
MTA1 MTA1: Metastasis-associated protein MTA1 0.032 0.040
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.032 0.040
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.032 0.032
KLC2 KLC2: Kinesin light chain 2 0.031 0.056
PDCD4 PDCD4, H731: Programmed cell death protein 4 0.030 0.036
MEP1B MEP1B: Meprin A subunit beta precursor 0.029 0.041
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.029 0.054
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.114
STMN1 STMN1, LAP18, OP18: Stathmin 0.029 0.046
FKBP4 FKBP4: FK506-binding protein 4 0.029 0.139
CFL1 CFL1, CFL: Cofilin-1 0.029 0.046
SHC1 SHC1, RP11-307C12.1-001, hCG_1997126: SHC 0.029 0.029
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.029 0.071
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.029 0.032
EVL N/A 0.029 0.038
TXNRD1 TXNRD1: Thioredoxin reductase 1, cytoplasmic precursor 0.029 0.046
DLG1 N/A 0.029 0.038
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
CDC42 N/A 0.028 0.028
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.052
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.052
CACNB2 N/A 0.028 0.028
MATK 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
PHLDB2 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
TSC2 TSC2, TSC4: Tuberin 0.028 0.025
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
LNX1 N/A 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
CASP8 CASP8, MCH5: Caspase-8 precursor 0.028 0.165
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.028 0.025
MYO18A 0.028 0.025
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.028 0.028
CASP9 CASP9, MCH6: Caspase-9 precursor 0.028 0.165
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.028 0.165
BCR N/A 0.028 0.025
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
NCF4 N/A 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.165
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.083
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
C9orf88 N/A 0.028 0.028
PTPN7 N/A 0.028 0.028
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.028 0.165
AXIN1 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.028 0.025
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
MAPKAPK5 N/A 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.028
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.028 0.028
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.027 0.029
HIVEP1 N/A 0.027 0.027
FADD FADD, MORT1: Protein FADD 0.027 0.202
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.027 0.091
GTF2F2 N/A 0.027 0.027
XRCC1 XRCC1: DNA-repair protein XRCC1 0.027 0.091
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.027 0.036
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.026 0.032
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.026 0.152
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.026
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.026
PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 0.026 0.026
CP110 N/A 0.026 0.032
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.026 0.029
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.028
CAMK2A N/A 0.025 0.025
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.028
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.075
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.025
RAB5B RAB5B: Ras-related protein Rab-5B 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.075
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.028
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.025 0.025
LMO6 LMO6: LIM domain only protein 6 0.025 0.025
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.025 0.028
CAMKK1 N/A 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
EPN2 N/A 0.025 0.025
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
RAC1 N/A 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
SCRIB N/A 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
GIT2 N/A 0.025 0.025
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.025 0.028
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
BCOR N/A 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 0.025
MAP2K3 N/A 0.025 0.025
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.025
DBNL N/A 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.075
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
GRK6 N/A 0.025 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.025
0.228
Total Score 5.74