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Evidence of Interaction Between CD2AP and WAS

The interaction score between CD2AP and WAS is 1.01E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between CD2AP and WAS = 0.47

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

4.62E-3
Orthology
OrganismCD2AP OrthologueWAS OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YGR136W 1 YOR181W 1
  • Y2H
  • Other

Get References From PubMed

bakers yeast YPR154W 1 YOR181W 1
  • Y2H
  • Immunoprecipitation
  • Other
  • AffinityCaptureWestern

Get References From PubMed

worm Q6A573 0.216 Q8MQE6 0.304

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.593
Domains Domains present in CD2AP and WAS:
Domains in CD2APDomains in WAS
IPR001452 SH3
IPR000108 Neutrophil cytosol factor 2
IPR003124 Actin-binding WH2
IPR000095 PAK-box/P21-Rho-binding
IPR011026 Wiscott-Aldrich syndrome, C-terminal
IPR000697 EVH1
IPR011993 PH_type.

The Chi square scores for co-occurrence of domains that are present in CD2AP and WAS are listed below.

Domain 1Domain 2Chi Square
IPR001452 SH3 IPR003124 Actin-binding WH2 199.546
IPR000108 Neutrophil cytosol factor 2 IPR003124 Actin-binding WH2 106.553
IPR001452 SH3 IPR011026 Wiscott-Aldrich syndrome, C-terminal 92.266
IPR001452 SH3 IPR000095 PAK-box/P21-Rho-binding 59.375
IPR001452 SH3 IPR000697 EVH1 52.1359
IPR000108 Neutrophil cytosol factor 2 IPR011026 Wiscott-Aldrich syndrome, C-terminal 43.3348
IPR001452 SH3 IPR011993 PH_type. 29.6332
IPR000108 Neutrophil cytosol factor 2 IPR000095 PAK-box/P21-Rho-binding 28.8443
IPR000108 Neutrophil cytosol factor 2 IPR000697 EVH1 19.3021
IPR000108 Neutrophil cytosol factor 2 IPR011993 PH_type. 15.9415

The background colour of the table refers to:

  • Blue Domain is only present in CD2AP
  • Yellow Domain is only present in WAS
  • Green Domain is present in both CD2AP and WAS

0.165
Post-translational Modifications

Protein: CD2AP

PTMResidueReference
Phosphotyrosine 88 HPRD

Protein: WAS

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 291 PubMed, HPRD
Phosphorylation 291 PubMed, HPRD
Phosphorylation 483 PubMed, HPRD
Phosphorylation 484 PubMed, HPRD
Phosphoserine 482 PubMed, HPRD
Phosphoserine 483 PubMed, HPRD
Phosphotyrosine 290 HPRD
Localisation

Protein: CD2AP

LocalisationReference
Plasma membrane HPRD
Nucleolus HPRD
Cytoplasm HPRD

Protein: WAS

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD
Transitive Score

The common interactors between CD2AP and WAS that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between CD2AP andWAS. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , CD2AP has 1210 interactors and WAS has 1502 interactors of which there are 892 common interactors.

Common InteractorName of Common InteractorScore for CD2AP-Interactor (?)Score for WAS-Interactor (?)
WASL WASL: Neural Wiskott-Aldrich syndrome protein 29.20 29.20
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 20.60 0.078
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 10.40 0.099
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 6.64 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 6.64 0.075
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 5.18 0.097
PRKCB1 N/A 1.33 0.025
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.995 0.136
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.964 0.426
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.852 0.307
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.763 0.275
NEDD4L N/A 0.593 0.593
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.515 0.416
SYK SYK: Tyrosine-protein kinase SYK 0.515 0.763
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.515 1.62
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.510 0.097
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.503 0.066
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.503 0.032
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.461 0.461
RPS6KB1 N/A 0.461 0.372
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.461 0.372
CSK CSK: Tyrosine-protein kinase CSK 0.461 1.62
PRKCH PRKCH, PKCL, PRKCL: Protein kinase C eta type 0.451 0.044
FUBP1 N/A 0.430 0.070
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.416 0.852
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.416 0.461
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.385 0.078
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.385 0.461
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.372 0.461
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 24.50
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.372 0.139
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.372 1.62
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 4.88
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.372 0.372
CRKL CRKL: Crk-like protein 0.372 14.60
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.822
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.372 0.461
VAV1 VAV1, VAV: Proto-oncogene vav 0.372 260.00
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.372 0.763
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.340 0.0446
PLEK PLEK, P47: Pleckstrin 0.340 0.541
JAK1 0.307 0.763
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.515
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.307 0.110
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.307 0.096
MSN MSN: Moesin 0.275 0.822
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.275 0.046
WASPIP N/A 0.275 431.00
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.275 0.763
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.275 0.763
CXorf9 N/A 0.275 1.62
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.275 0.822
LYN LYN: Tyrosine-protein kinase Lyn 0.275 1.62
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.274 0.472
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.274 0.0446
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.260 0.052
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.251 0.416
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.251 0.260
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.251 0.123
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.251 0.191
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.251 0.307
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.246 0.137
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.246 0.141
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.246 0.040
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.233 0.046
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.233 431.00
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 1.62
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.233 0.461
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.233 0.129
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.233 0.046
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.233 0.275
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.233 0.038
FNBP1 N/A 0.233 40.60
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.225 0.372
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.225 0.069
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.225 0.114
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.225 0.275
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.225 0.188
VIL2 N/A 0.225 0.139
NCK2 NCK2: Cytoplasmic protein NCK2 0.225 14.60
DOK1 DOK1: Docking protein 1 0.225 0.233
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.210 0.063
PHB2 PHB2, BAP, REA: Prohibitin-2 0.210 0.0425
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.210 0.026
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.210 0.152
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.202 0.153
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.202 0.124
LILRB1 N/A 0.202 0.074
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.202 0.157
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.202 0.124
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.191 0.307
VASP VASP: Vasodilator-stimulated phosphoprotein 0.191 0.852
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.191 0.152
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.191 1.81
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.191 0.026
STK16 N/A 0.191 0.191
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.188 0.129
CDK2 CDK2: Cell division protein kinase 2 0.188 0.171
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.188 0.078
CDK4 CDK4: Cell division protein kinase 4 0.188 0.171
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.188 0.763
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.188 4.88
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.188 0.136
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.188 0.385
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.188 0.275
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.181 0.246
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.181 0.246
SOS1 SOS1: Son of sevenless homolog 1 0.181 0.181
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.181 0.113
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.171 14.60
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.171 0.114
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.136
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.171 0.233
PLD1 PLD1: Phospholipase D1 0.171 0.056
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.171 0.225
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.171 0.225
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.171 86.60
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.171 0.171
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.171 0.275
APS SH2B2, APS: SH2B adapter protein 2 0.171 0.171
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.166 0.561
STAT2 STAT2: Signal transducer and activator of transcription 2 0.166 0.166
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.166 0.057
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.165
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.083
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.083
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.165
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.165 0.148
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.165 0.148
PSCD2 N/A 0.165 0.083
MAPK15 N/A 0.165 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.083
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.165
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.163 0.032
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.160 0.683
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.155 0.114
WEE1 WEE1: Wee1-like protein kinase 0.155 0.110
HD HD, IT15: Huntingtin 0.155 0.070
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.155 0.152
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.152 0.152
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.152 0.251
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.152 0.077
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.152 0.225
GAB2 N/A 0.152 0.155
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.152 1.81
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.148 0.064
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.075
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.075
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.148 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.148
STAT3 0.148 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 7.88
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.148 0.075
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.148 0.148
ARHGEF7 N/A 0.148 0.075
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 7.88
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.075
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.148 0.075
ELMO1 N/A 0.148 0.075
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.146 0.063
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.146 16.60
SRPR SRPR: Uncharacterized protein SRPR 0.144 0.087
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.144 0.461
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.141 0.032
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.140 1.81
THOP1 THOP1: Thimet oligopeptidase 0.139 0.029
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.275
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.139 0.822
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.139 0.461
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.139 1.62
CDK7 CDK7, MO15: Cell division protein kinase 7 0.139 0.171
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.139 0.136
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.139 0.110
STK10 STK10: Uncharacterized protein STK10 0.139 1.62
ACTG1 ACTB: Actin, cytoplasmic 1 0.139 202.00
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.136 0.110
PLD2 PLD2: Phospholipase D2 0.136 0.056
STAM2 STAM2: Signal transducing adapter molecule 2 0.136 0.136
HCK N/A 0.136 40.60
RDX RDX: Radixin 0.136 0.044
RASA3 RASA3: Ras GTPase-activating protein 3 0.136 0.225
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.136 0.110
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.136 0.171
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.129 0.046
QARS QARS: Glutaminyl-tRNA synthetase 0.129 0.078
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.129 0.063
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.129 0.129
XPO1 XPO1, CRM1: Exportin-1 0.129 0.139
HNRPK N/A 0.129 0.129
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.126 0.057
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.126 1.19
EPOR EPOR: Erythropoietin receptor precursor 0.126 0.032
GHR GHR: Growth hormone receptor precursor 0.126 0.037
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.126 0.372
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.123 0.049
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.123 0.251
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.152
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.123 0.152
GAB1 GAB1: GRB2-associated-binding protein 1 0.123 0.062
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.123 0.109
SEC24B SEC24B: Protein transport protein Sec24B 0.118 0.063
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.114 0.114
GMIP GMIP: GEM-interacting protein 0.114 0.822
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.114 0.110
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.114 0.171
BRPF1 BRPF1, BR140: Peregrin 0.114 0.046
TLN1 TLN1: Uncharacterized protein TLN1 0.114 0.188
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.461
ATM ATM: Serine-protein kinase ATM 0.114 0.275
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.171
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.113 0.033
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.113 0.032
LIG1 LIG1: DNA ligase 1 0.112 0.051
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.111 0.0446
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.111 0.137
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.111 0.141
PHF10 N/A 0.111 0.032
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.110 0.0308
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.110 4.67
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.110 0.097
COBL N/A 0.110 0.088
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.109 0.049
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.109 0.098
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.109 0.109
KIR3DL1 N/A 0.109 0.049
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.109 0.049
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.109 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.109 0.049
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.109 0.049
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.109 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.109 0.049
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.109 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.109 0.049
FN1 N/A 0.109 0.049
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.109 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.109 0.049
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.109 0.372
IRS1 IRS1: Insulin receptor substrate 1 0.109 0.049
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.109 0.062
IRS2 IRS2: Insulin receptor substrate 2 0.109 0.155
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.104 0.110
ETS2 ETS2: Protein C-ets-2 0.100 0.046
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.100 0.057
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.100 0.153
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.100 0.057
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.100 0.091
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.100 0.057
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.100 0.090
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.099 0.044
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.099 0.044
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.099 0.099
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.099 0.050
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.099 0.078
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.098 0.098
BMX N/A 0.098 0.109
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.098 0.044
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.044
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.098 0.098
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.098 0.098
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.098 0.098
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.098 0.098
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.098 0.044
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.098 0.044
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.098 0.098
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.049
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.050
TTN N/A 0.097 0.049
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.097 0.088
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.097 0.110
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.097 0.056
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.097 5.88
DAB1 DAB1: Disabled homolog 1 0.097 0.044
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.097 0.088
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.0971 0.080
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.515
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.096 1.81
PRKAA1 N/A 0.096 0.191
STX7 STX7: Syntaxin-7 0.090 0.040
KIT KIT: Mast/stem cell growth factor receptor precursor 0.090 0.073
STAT4 STAT4: Signal transducer and activator of transcription 4 0.090 0.148
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.090 0.073
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.088 0.099
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.088 0.099
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.088 0.078
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.088 0.088
PSD TYL: TYL protein 0.088 0.044
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.087 0.416
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.087 0.052
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.070
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.087 0.032
PPARBP N/A 0.087 0.078
ABCF1 N/A 0.087 0.052
FLII FLII, FLIL: Protein flightless-1 homolog 0.087 0.078
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.086 0.461
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.165
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.083 0.028
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.083 0.148
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.083 0.083
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.165
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.082 0.157
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.082 0.0446
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.082 0.340
CRLF3 N/A 0.082 0.541
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.082 0.472
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.0818 0.032
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.081 0.065
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.081 0.032
IL9R IL9R: Interleukin-9 receptor precursor 0.081 0.037
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.081 0.057
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.078 0.099
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.078 0.050
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.078 0.099
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.078 0.078
RPL8 RPL8: 60S ribosomal protein L8 0.078 0.063
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.078 0.038
VCP VCP: Transitional endoplasmic reticulum ATPase 0.078 0.046
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.078 0.046
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.078 0.063
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.078 0.038
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.078 0.063
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.078 0.171
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.078 0.063
COPA COPA: Coatomer subunit alpha 0.078 0.046
CDC23 CDC23: Cell division cycle protein 23 homolog 0.078 0.038
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.129
LDHB LDHB: L-lactate dehydrogenase B chain 0.078 0.038
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.078 0.063
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.078 0.038
CTPS CTPS: CTP synthase 1 0.078 0.029
LPXN LPXN, LDLP: Leupaxin 0.078 0.763
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.078 0.078
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.078
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.078 0.063
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.078 0.078
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.078 0.078
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.078 0.046
NRAS NRAS, HRAS1: GTPase NRas precursor 0.078 0.275
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.078 0.046
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.078 0.225
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.129
CCT8 CCT8: Uncharacterized protein CCT8 0.078 0.038
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.078 0.054
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.078 0.063
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.078 0.046
RPS10 RPS10: 40S ribosomal protein S10 0.078 0.078
CDK6 CDK6: Cell division protein kinase 6 0.077 0.136
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.109
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.076 0.171
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.075 0.166
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.075 0.157
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.075 0.074
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.075 0.025
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
CDC25A CDC25A: M-phase inducer phosphatase 1 0.075 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.075 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.075 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.075 0.025
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.148
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 39.20
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.075 0.148
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.148
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.074 0.032
NBN NBN, NBS, NBS1, P95: Nibrin 0.074 0.0446
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.074 0.027
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.074 0.0446
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.074 0.036
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.074 0.032
DDX21 DDX21: Nucleolar RNA helicase 2 0.074 0.036
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.074 0.032
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.073 0.058
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.073 0.246
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.073 0.058
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.073 0.064
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.0727 0.0727
PRLR PRLR: Prolactin receptor precursor 0.0727 0.029
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.072 0.072
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.072 0.058
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.072 0.026
DNM2 N/A 0.070 0.070
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.210
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.070 0.032
TRRAP N/A 0.070 0.032
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.070 0.0425
CHUK N/A 0.070 0.052
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.070 0.0425
ESPL1 N/A 0.070 0.026
API5 N/A 0.070 0.0425
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.070 0.030
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.069 0.225
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.069 0.136
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.069 0.110
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.069 0.038
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.069 0.171
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.069 0.275
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.0688 0.034
CSNK1G3 CSNK1G3: Casein kinase I isoform gamma-3 0.067 0.067
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.067 2.53
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.066 0.032
NUP153 N/A 0.066 0.032
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.066 0.066
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.066 0.040
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.066 0.032
TIAL1 TIAL1: Nucleolysin TIAR 0.066 0.040
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.066 0.066
VDP DKFZp451D234: Putative uncharacterized protein DKFZp451D234 0.066 0.032
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.066 0.032
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.066 0.040
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.066 0.032
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.066 0.040
CUL4B N/A 0.066 0.032
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.066 0.040
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.066 0.032
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.066 0.032
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.066 0.032
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.066 0.246
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.066 0.032
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.066 0.032
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.065 0.058
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.065 0.065
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.065 0.058
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.065 0.026
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.065 0.058
MET MET: Hepatocyte growth factor receptor precursor 0.065 0.0727
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.065 0.029
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.065 0.073
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.065 0.029
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.065 0.032
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.065 0.026
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.064 0.064
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.064 0.065
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.064 0.058
INSR INSR: Insulin receptor precursor 0.064 0.064
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.064 0.058
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.064 0.064
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.064 0.065
TPT1 TPT1: Translationally-controlled tumor protein 0.063 0.078
MDN1 MDN1, KIAA0301: Midasin 0.063 0.086
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.063
THOC1 THOC1, HPR1: THO complex subunit 1 0.063 0.038
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.063 0.763
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.063 0.029
CASP3 CASP3, CPP32: Caspase-3 precursor 0.063 0.029
LCP1 LCP1, PLS2: Plastin-2 0.063 43.70
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.078
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.063 0.461
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.063 0.063
HSP90AA1 Hsp89-alpha-delta-N 0.063 0.029
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.063 0.063
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.063 1.62
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.063 0.078
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.063 0.129
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.063 0.078
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.063 0.038
KLHDC4 N/A 0.063 0.078
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.063 0.171
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.063 2.46
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.063 0.118
EEF2 EEF2, EF2: Elongation factor 2 0.063 0.275
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.063 0.046
PTPN11 N/A 0.063 0.029
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.063 0.763
GRLF1 N/A 0.062 0.109
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.062 0.123
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.062 0.062
CD44 N/A 0.061 0.253
SORL1 SORL1: Sortilin-related receptor precursor 0.060 0.227
RASA4 RASA4, CAPRI, GAPL, KIAA0538: Ras GTPase-activating protein 4 0.060 0.060
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 0.060 0.060
WASF2 WASF2, WAVE2: Wiskott-Aldrich syndrome protein family member 2 0.060 0.123
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.059 0.025
CDC42EP3 CDC42EP3, BORG2, CEP3: Cdc42 effector protein 3 0.059 0.265
CDK9 CDK9, CDC2L4: Cell division protein kinase 9 0.059 0.059
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.058 0.065
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.058 0.064
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.058 0.065
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.058 0.026
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.058 0.026
MCOLN1 MCOLN1, ML4, MSTP080: Mucolipin-1 0.057 0.056
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.057 0.0818
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.056 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.056 0.148
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.056 0.110
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.056 0.275
CDK5 CDK5: Cell division protein kinase 5 0.056 0.110
DYRK3 N/A 0.056 0.088
CDKL5 N/A 0.056 0.109
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.056 0.099
SPTAN1 N/A 0.056 0.110
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.055 0.123
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.123
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.054 0.056
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.052 0.026
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.052 0.087
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.052 0.070
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.052 0.0425
MPG N/A 0.052 0.052
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.087
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.052 0.372
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.060
CIITA CIITA, MHC2TA: MHC class II transactivator 0.052 0.070
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.032
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.052 1.81
UBAP2 N/A 0.052 0.032
IPO7 IPO7: Uncharacterized protein IPO7 0.052 0.077
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.052 0.026
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.052 0.0727
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
GRB10 N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
CDC42EP1 CDC42EP1, BORG5, CEP1, MSE55: Cdc42 effector protein 1 0.051 0.051
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.051 0.100
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.051 0.075
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.051 0.027
CD7 CD7: T-cell antigen CD7 precursor 0.051 0.036
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.051 1.07
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.050 0.148
CTTN CTTN, EMS1: Src substrate cortactin 0.050 0.070
ARHGEF18 ARHGEF18: ARHGEF18 protein 0.050 0.083
PLEKHO1 PLEKHO1, CKIP1, OC120, HQ0024c: Pleckstrin homology domain-containing family O m 0.050 0.042
SCAP2 SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2 0.050 0.294
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.049 0.04
SORBS3 SORBS3, SCAM1: Vinexin 0.049 4.67
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.049 0.136
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.049 0.097
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.049 0.136
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.049 0.088
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.049 0.171
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.048 0.144
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.047 0.148
GSN GSN: Gelsolin precursor 0.047 0.025
SVIL SVIL: Supervillin 0.047 0.025
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.046 0.029
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.046 0.029
GPI GPI: Glucose-6-phosphate isomerase 0.046 0.029
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.046 0.046
CAT CAT: Catalase 0.046 0.029
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.046 0.046
SYMPK SYMPK, SPK: Symplekin 0.046 0.029
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.372
SAPS3 N/A 0.046 0.063
GSK3B N/A 0.046 0.078
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.046 0.241
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.046 0.029
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.046 0.461
RP2 RP2: Protein XRP2 0.046 0.078
EXOC2 N/A 0.046 0.046
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.038
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.046 0.038
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 2.45
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.046
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.046 0.097
ALK ALK: ALK tyrosine kinase receptor precursor 0.046 0.046
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0446 0.027
ELF1 ELF1: ETS-related transcription factor Elf-1 0.0446 0.157
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.0446 0.036
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.0446 0.074
SET SET: Protein SET 0.0446 0.027
NCOA3 N/A 0.0446 0.0446
TOP2B N/A 0.0446 0.027
RBM14 RBM14, SIP: RNA-binding protein 14 0.0446 0.036
MATR3 MATR3, KIAA0723: Matrin-3 0.0446 0.027
PTMA N/A 0.0446 0.0446
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.0446 0.036
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.0446 0.074
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.0446 0.032
HDAC3 HDAC3: Histone deacetylase 3 0.0446 0.032
IFI16 N/A 0.0446 0.157
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0446 0.036
GNB2L1 Lung cancer oncogene 7 0.0446 0.0446
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.0446 0.036
MAP4K2 MAP4K2, GCK, RAB8IP: Mitogen-activated protein kinase kinase kinase kinase 2 0.044 0.036
PRKX PRKX, PKX1: Serine/threonine-protein kinase PRKX 0.044 0.074
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.088
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.044 0.110
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.044 0.049
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.044 0.049
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.044 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.044 0.049
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.044 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.044 0.036
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.044
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.044 0.098
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.044 0.036
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.044 0.054
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.0425 0.087
MVP MVP, LRP: Major vault protein 0.0425 0.430
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.0425 0.026
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.052
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.0425 0.029
MARK2 N/A 0.0425 0.087
DAPP1 N/A 0.0425 0.087
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.0425 0.078
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.0425 0.078
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.307
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.0425 0.191
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.042 0.053
LIG4 LIG4: DNA ligase 4 0.041 0.033
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.0513
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.0407 0.032
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.0407 0.081
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.041 0.090
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.041 0.066
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.041 0.040
ARHGEF7 ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB: Rho guanine nucleotide exchange 0.041 0.0308
SAMSN1 SAMSN1, HACS1: SAM domain-containing protein SAMSN-1 0.041 0.050
DYRK4 DYRK4: Dual specificity tyrosine-phosphorylation-regulated kinase 4 0.041 0.028
PLCB2 0.041 0.081
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.040 0.066
CORO1C CORO1C, CRNN4: Coronin-1C 0.040 0.032
PPP1R8 N/A 0.040 0.040
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.040 0.032
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.040 0.032
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.040 0.040
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.040 0.040
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.040 0.045
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.040 0.032
YY1 YY1: Transcriptional repressor protein YY1 0.040 0.040
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.040 0.066
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.040 0.032
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.040 0.040
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.040 0.066
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.040 0.032
WBSCR20A N/A 0.040 0.032
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.040 0.066
CNTN4 CNTN4: Contactin-4 precursor 0.040 0.044
CNTN1 CNTN1: Contactin-1 precursor 0.040 0.044
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.040 0.044
BSG N/A 0.040 0.044
TLN2 TLN2: Uncharacterized protein TLN2 0.040 0.040
SEMA4D SEMA4D, CD100, SEMAJ: Semaphorin-4D precursor 0.039 0.108
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.038 0.129
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.038 0.038
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.038 0.046
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.038 0.063
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.038 0.038
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.029
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.038 0.276
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.038 0.225
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.038 0.225
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.038 0.110
AIP AIP, XAP2: AH receptor-interacting protein 0.038 0.046
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.038 0.275
RIN1 RIN1: Ras and Rab interactor 1 0.037 0.110
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.037 0.027
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.037 0.078
ACTB ACTG1, ACTB, ACTG: Actin, cytoplasmic 2 0.037 41.20
ARAF ARAF, ARAF1, PKS, PKS2: A-Raf proto-oncogene serine/threonine-protein kinase 0.036 0.060
ADRBK2 ADRBK2, BARK2, GRK3: Beta-adrenergic receptor kinase 2 0.036 0.074
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.036 0.074
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.036 0.027
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.036 0.032
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.036 0.0446
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.036 0.0446
WDR1 N/A 0.036 0.0446
ARFGAP1 N/A 0.036 0.091
ZNF267 ZNF267: Zinc finger protein 267 0.036 0.036
TCOF1 N/A 0.036 0.027
KIAA0853 N/A 0.036 0.036
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.036 0.0446
IRF3 IRF3: Interferon regulatory factor 3 0.036 0.036
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.036 0.027
HLA-DRA 0.036 0.0446
RB1 RB1: Retinoblastoma-associated protein 0.036 0.027
SNCB SNCB: Beta-synuclein 0.035 0.035
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.035 0.035
LTK LTK, TYK1: Leukocyte tyrosine kinase receptor precursor 0.035 0.029
SOS2 SOS2: Son of sevenless homolog 2 0.035 0.047
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.033 0.099
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.0333 0.0333
MCF2 MCF2, DBL: Proto-oncogene DBL 0.033 0.098
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.033 0.036
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.032 0.032
ATP2B1 N/A 0.032 0.0453
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.032 0.136
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.087
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.032 0.032
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.032 0.087
FLNA FLNA, FLN, FLN1: Filamin-A 0.032 0.070
SAT SAT1, SAT: Diamine acetyltransferase 1 0.032 0.070
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.032 0.029
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.032 0.307
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.032 0.040
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.032 0.032
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.032 0.066
CUL5 CUL5, VACM1: Cullin-5 0.032 0.032
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.032 0.040
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.032 0.032
ENTPD4 ENTPD4, KIAA0392, LALP70, LYSAL1: Ectonucleoside triphosphate diphosphohydrolase 0.032 0.032
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.032 0.040
EP300 N/A 0.032 0.040
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.032 0.066
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.032 0.040
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.032 0.032
ITGB7 ITGB7: Integrin beta-7 precursor 0.032 0.304
IL27RA N/A 0.032 0.057
BTN3A3 BTN3A3, BTF3: Butyrophilin subfamily 3 member A3 precursor 0.032 0.065
IL10RB IL10RB, CRFB4, D21S58, D21S66: Interleukin-10 receptor beta chain precursor 0.032 0.027
RAB11A RAB11A, RAB11: Ras-related protein Rab-11A 0.032 0.093
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.031 0.050
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.031 0.044
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.0308 0.049
ARHGEF3 ARHGEF3: Rho guanine nucleotide exchange factor 3 0.0308 0.083
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.0308 0.050
FYN N/A 0.0308 0.083
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.0308 0.050
KCNH2 KCNH2, ERG, ERG1, HERG, HERG1: Potassium voltage-gated channel subfamily H membe 0.030 0.030
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.030 0.852
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.030 0.030
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.030 0.030
PTPRZ1 N/A 0.029 0.029
ITGB4 N/A 0.029 0.065
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.029 0.032
MEP1B MEP1B: Meprin A subunit beta precursor 0.029 0.029
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.029 0.029
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.029
SNRK SNRK, KIAA0096, SNFRK: SNF-related serine/threonine-protein kinase 0.029 0.029
CFL1 CFL1, CFL: Cofilin-1 0.029 12.30
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.029 0.078
EVL N/A 0.029 0.046
ADAM8 ADAM8, MS2: ADAM 8 precursor 0.029 0.207
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
CDC42 N/A 0.028 0.028
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
PKP4 PKP4: Plakophilin-4 0.028 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.028 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.165
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
CACNB2 N/A 0.028 0.028
MATK 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
PHLDB2 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
TSC2 TSC2, TSC4: Tuberin 0.028 0.025
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.165
LNX1 N/A 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
CASP8 CASP8, MCH5: Caspase-8 precursor 0.028 0.028
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.028 0.075
MYO18A 0.028 0.025
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.028 0.165
CASP9 CASP9, MCH6: Caspase-9 precursor 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.165
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.028 0.028
BCR N/A 0.028 0.025
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
NCF4 N/A 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.165
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
C9orf88 N/A 0.028 0.028
PTPN7 N/A 0.028 0.028
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.028 0.028
AXIN1 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.028 0.025
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.052
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
MAPKAPK5 N/A 0.028 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.083
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.028 0.165
PMP2 PMP2: Myelin P2 protein 0.028 0.044
VAV3 VAV3: Protein vav-3 0.028 2.36
RIN3 N/A 0.028 0.263
GRAP GRAP: GRB2-related adapter protein 0.028 7.31
RASA2 RASA2, GAP1M, RASGAP: Ras GTPase-activating protein 2 0.028 0.036
PCTK2 PCTK2: Serine/threonine-protein kinase PCTAIRE-2 0.028 0.028
ARHGAP26 ARHGAP26, GRAF, KIAA0621, OPHN1L: Rho GTPase-activating protein 26 0.028 0.123
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.027 0.241
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
MID2 N/A 0.027 0.027
PXK PXK: PX domain-containing protein kinase-like protein 0.027 0.027
TRIM9 TRIM9, KIAA0282, RNF91: Tripartite motif-containing protein 9 0.027 0.027
SHANK1 SHANK1: SH3 and multiple ankyrin repeat domains protein 1 0.027 0.027
CAMKK1 CAMKK1, CAMKKA: Calcium/calmodulin-dependent protein kinase kinase 1 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
ABI3 ABI3, NESH: ABI gene family member 3 0.027 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.027
PDIK1L PDIK1L, CLIK1L: Serine/threonine-protein kinase PDIK1L 0.027 0.027
CASKIN1 N/A 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.027
ANKK1 ANKK1, PKK2, SGK288: Ankyrin repeat and protein kinase domain-containing protein 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.027
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.027 0.0446
RBM6 RBM6, DEF3: RNA-binding protein 6 0.027 0.027
FADD FADD, MORT1: Protein FADD 0.027 0.027
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.027 0.032
XRCC1 XRCC1: DNA-repair protein XRCC1 0.027 0.027
ST8SIA4 ST8SIA4, PST, PST1, SIAT8D: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransfe 0.027 0.0446
H1FX H1FX: Histone H1x 0.027 0.036
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.027 0.027
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.027 0.032
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.027 0.074
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.0264 0.029
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.0264 0.026
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.026 0.032
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.026 0.032
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.026 0.033
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.026 0.029
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.026 0.065
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.026 0.026
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.026 0.058
DCC DCC: Netrin receptor DCC precursor 0.026 0.029
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.026 0.026
TNC TNC, HXB: Tenascin precursor 0.026 0.029
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.026 0.0425
AHNAK AHNAK: AHNAK protein 0.026 0.070
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.026 0.032
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.127
PDLIM1 PDLIM1, CLIM1, CLP36: PDZ and LIM domain protein 1 0.026 0.123
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.026 0.109
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.026 0.136
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.026 0.144
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.026 0.066
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.025
CAMK2A N/A 0.025 0.025
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.148
RAB5B RAB5B: Ras-related protein Rab-5B 0.025 0.148
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.025
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.025
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.025 0.075
LMO6 LMO6: LIM domain only protein 6 0.025 0.148
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.025 0.148
CAMKK1 N/A 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
EPN2 N/A 0.025 1.33
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
RAC1 N/A 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.148
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
SCRIB N/A 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.148
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.148
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.148
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
GIT2 N/A 0.025 0.075
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.025 0.148
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
BCOR N/A 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 1.33
MAP2K3 N/A 0.025 0.025
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 1.33
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.148
DBNL N/A 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.148
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.075
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
GRK6 N/A 0.025 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.148
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.075
0.347
Total Score 1.01E4