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Evidence of Interaction Between OPRM1 and F2R

The interaction score between OPRM1 and F2R is 3.07.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology N/A N/A
Domains Domains present in OPRM1 and F2R:
Domains in OPRM1Domains in F2R
IPR000276 Rhodopsin-like GPCR superfamily
IPR000105 Mu opioid receptor
IPR001418 Opioid receptor
IPR000276 Rhodopsin-like GPCR superfamily
IPR003912 Protease-activated receptor
IPR000935 Thrombin receptor

The Chi square scores for co-occurrence of domains that are present in OPRM1 and F2R are listed below.

Domain 1Domain 2Chi Square
IPR000276 Rhodopsin-like GPCR superfamily IPR000276 Rhodopsin-like GPCR superfamily 11.8987

The background colour of the table refers to:

  • Blue Domain is only present in OPRM1
  • Yellow Domain is only present in F2R
  • Green Domain is present in both OPRM1 and F2R

 0.034
Post-translational Modifications

Protein: OPRM1

PTMResidueReference
Phosphorylation 244 PubMed, HPRD
Phosphorylation 418 PubMed, HPRD
Phosphorylation 420 PubMed, HPRD
Phosphorylation 427 PubMed, HPRD
Phosphorylation 434 PubMed, HPRD
Phosphorylation 439 PubMed, HPRD

Protein: F2R

PTMResidueReference
Phosphorylation 375 PubMed, HPRD
Phosphorylation 376 PubMed, HPRD
Phosphorylation 384 PubMed, HPRD
Phosphorylation 391 PubMed, HPRD
Phosphorylation 392 PubMed, HPRD
Phosphorylation 395 PubMed, HPRD
Phosphorylation 396 PubMed, HPRD
Phosphorylation 397 PubMed, HPRD
Phosphorylation 399 PubMed, HPRD
Phosphorylation 400 PubMed, HPRD
Phosphorylation 406 PubMed, HPRD
Phosphorylation 410 PubMed, HPRD
Phosphorylation 412 PubMed, HPRD
Phosphorylation 413 PubMed, HPRD
Phosphorylation 418 PubMed, HPRD
Phosphorylation 425 PubMed, HPRD
Proteolytic Cleavage 41 PubMed, HPRD
Localisation

Protein: OPRM1

LocalisationReference
ER HPRD
Golgi HPRD
Plasma membrane HPRD

Protein: F2R

LocalisationReference
Plasma membrane HPRD
Endosome HPRD
Transitive Score

The common interactors between OPRM1 and F2R that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between OPRM1 andF2R. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , OPRM1 has 551 interactors and F2R has 539 interactors of which there are 282 common interactors.

Common InteractorName of Common InteractorScore for OPRM1-Interactor (?)Score for F2R-Interactor (?)
GNAL GNAL: Guanine nucleotide-binding protein G(olf) subunit alpha 1.53 0.786
GNAS GNAS, GNAS1, GSP: Guanine nucleotide-binding protein G(s) subunit alpha isoforms 1.53 1.05
CCL14 CCL14, NCC2, SCYA14: Small-inducible cytokine A14 precursor 1.53 0.644
CCL7 MCP-3: Monocyte chemotactic protein-3 1.53 0.626
GNA14 GNA14: Guanine nucleotide-binding protein alpha-14 subunit 1.37 1.21
CCL22 CCL22, A-152E5.1, MDC, SCYA22: Small-inducible cytokine A22 precursor 0.540 0.644
PF4V1 PF4V1, SCYB4V1: Platelet factor 4 variant precursor 0.540 0.902
CCL2 CCL2, MCP1, SCYA2: Small-inducible cytokine A2 precursor 0.540 1.48
CCL1 CCL1, SCYA1: Small-inducible cytokine A1 precursor 0.540 0.731
CCL24 CCL24, MPIF2, SCYA24: Small-inducible cytokine A24 precursor 0.540 1.13
PPBP PPBP, CTAP3, SCYB7, TGB1, THBGB1: Platelet basic protein precursor 0.540 0.731
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.540 1.50
CCL5 CCL5, D17S136E, SCYA5: Small-inducible cytokine A5 precursor 0.540 0.902
LOC643930 CCL3L1, D17S1718, G0S19-2, SCYA3L1: Small-inducible cytokine A3-like 1 precursor 0.540 0.980
CCL13 CCL13, MCP4, NCC1, SCYA13: Small-inducible cytokine A13 precursor 0.540 1.13
CXCL11 CXCL11, ITAC, SCYB11, SCYB9B: Small-inducible cytokine B11 precursor 0.540 0.902
GNAI1 GNAI1: Guanine nucleotide-binding protein G(i), alpha-1 subunit 0.540 0.859
PF4 PF4, CXCL4, SCYB4: Platelet factor 4 precursor 0.540 0.731
XCL1 XCL1, LTN, SCYC1: Lymphotactin precursor 0.540 1.13
CXCL9 CXCL9, CMK, MIG, SCYB9: Small-inducible cytokine B9 precursor 0.540 0.902
CXCL10 CXCL10, INP10, SCYB10: Small-inducible cytokine B10 precursor 0.540 1.13
CXCL1 CXCL1, GRO, GRO1, GROA, MGSA, SCYB1: Growth-regulated protein alpha precursor 0.540 1.13
IL8 IL8: Interleukin-8 precursor 0.540 0.902
GNAZ GNAZ: Guanine nucleotide-binding protein G(z) subunit alpha 0.540 0.859
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 2 0.540 0.859
GNAT1 GNAT1, GNATR: Guanine nucleotide-binding protein G(t), alpha-1 subunit 0.540 1.50
GNAT2 GNAT2, GNATC: Guanine nucleotide-binding protein G(t), alpha-2 subunit 0.540 0.975
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.540 0.975
CXCL5 CXCL5, ENA78, SCYB5: Small-inducible cytokine B5 precursor 0.540 1.13
CXCL12 Stromal cell-derived factor 1 delta 0.540 0.731
CCL11 CCL11, SCYA11: Eotaxin precursor 0.540 0.902
CCL21 CCL21, SCYA21, UNQ784/PRO1600: Small-inducible cytokine A21 precursor 0.540 0.644
CCL26 CCL26, SCYA26, UNQ216/PRO242: Small-inducible cytokine A26 precursor 0.540 0.980
GNAI2 Galphai2 protein 0.540 1.20
CCL8 CCL8, MCP2, SCYA10, SCYA8: Small-inducible cytokine A8 precursor 0.540 1.13
CCL4 CCL4, CCL4L, LAG1, MIP1B, SCYA4, SCYA4L: Small-inducible cytokine A4 precursor 0.540 1.13
CCL15 CCL15, MIP5, NCC3, SCYA15: Small-inducible cytokine A15 precursor 0.540 0.980
GNAQ GNAQ, GAQ: Guanine nucleotide-binding protein G(q) subunit alpha 0.484 0.975
GNA12 GNA12: Guanine nucleotide-binding protein alpha-12 subunit 0.484 0.975
GNA11 GNA11, GA11: Guanine nucleotide-binding protein subunit alpha-11 0.484 0.975
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 1 0.484 1.30
GNA13 GNA13: Guanine nucleotide-binding protein alpha-13 subunit 0.484 1.98
CXCL6 CXCL6, GCP2, SCYB6: Small-inducible cytokine B6 precursor 0.140 0.330
CXCL3 CXCL3, GRO3, GROG, SCYB3: Macrophage inflammatory protein 2-beta precursor 0.140 0.330
CCL17 CCL17, SCYA17, TARC: Small-inducible cytokine A17 precursor 0.140 0.330
CCL28 CCL28, SCYA28: Small-inducible cytokine A28 precursor 0.140 0.217
CCL25 CCL25, SCYA25, TECK: Small-inducible cytokine A25 precursor 0.140 0.143
CCL23 MIP3, CCL23, MPIF1, SCYA23: Small-inducible cytokine A23 precursor 0.140 0.200
XCL2 XCL2, SCYC2: Cytokine SCM-1 beta precursor 0.140 0.217
CCL16 CCL16, ILINCK, NCC4, SCYA16: Small-inducible cytokine A16 precursor 0.140 0.143
CXCL13 CXCL13, BCA1, BLC, SCYB13: Small-inducible cytokine B13 precursor 0.140 0.162
CCL18 CCL18, AMAC1, DCCK1, MIP4, PARC, SCYA18: Small-inducible cytokine A18 precursor 0.140 0.162
CCL27 CCL27, ILC, SCYA27: Small-inducible cytokine A27 precursor 0.140 0.200
CCL3 CCL3, G0S19-1, MIP1A, SCYA3: Small-inducible cytokine A3 precursor 0.140 0.162
CX3CL1 CX3CL1, A-152E5.2, FKN, NTT, SCYD1: Fractalkine precursor 0.140 0.129
CCL19 CCL19, ELC, MIP3B, SCYA19: Small-inducible cytokine A19 precursor 0.140 0.143
CCL20 CCL20, LARC, MIP3A, SCYA20: Small-inducible cytokine A20 precursor 0.140 0.162
CXCL2 CXCL2, GRO2, GROB, MIP2A, SCYB2: Macrophage inflammatory protein 2-alpha precurs 0.140 0.200
ARL3 ARL3, ARFL3: ADP-ribosylation factor-like protein 3 0.126 0.251
NOS2A NOS2A, NOS2: Nitric oxide synthase, inducible 0.083 0.034
HPN HPN, TMPRSS1: Serine protease hepsin 0.083 0.109
NOS1 NOS1: Nitric-oxide synthase, brain 0.083 0.0453
BDKRB2 BDKRB2, BKR2: B2 bradykinin receptor 0.083 0.0513
AVPR2 AVPR2, ADHR, DIR, DIR3, V2R: Vasopressin V2 receptor 0.075 0.031
AVPR1A AVPR1A, AVPR1: Vasopressin V1a receptor 0.075 0.085
OPRD1 OPRD1, OPRD: Delta-type opioid receptor 0.075 0.031
OXTR OXTR: Oxytocin receptor 0.075 0.025
CANX CANX: Calnexin precursor 0.075 0.031
AVPR1B AVPR1B, AVPR3, VPR3: Vasopressin V1b receptor 0.075 0.025
TSHB TSHB: Thyrotropin subunit beta precursor 0.0688 0.072
ORM1 ORM1, AGP1: Alpha-1-acid glycoprotein 1 precursor 0.0688 0.072
RLN2 RLN2: Prorelaxin H2 precursor [Contains: Relaxin B chain; Relaxin A chain] 0.0688 0.100
LCN2 LCN2, HNL, NGAL: Neutrophil gelatinase-associated lipocalin precursor 0.0688 0.072
FSHB FSHB: Follitropin subunit beta precursor 0.0688 0.072
C4A C4A: Complement C4-A precursor 0.0688 0.109
AXIN1 0.0688 0.109
AGRP AGRP, AGRT, ART: Agouti-related protein precursor 0.0688 0.081
LHB LHB: Lutropin subunit beta precursor 0.0688 0.072
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.0688 0.072
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.0688 0.081
APOD APOD: Apolipoprotein D precursor 0.0688 0.072
EDN3 EDN3: Endothelin-3 precursor 0.0688 0.100
EDN2 EDN2: Endothelin-2 precursor 0.0688 0.100
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.0688 0.109
PTGDS PTGDS, PDS: Prostaglandin-H2 D-isomerase precursor 0.0688 0.065
RGS16 RGS16, RGSR: Regulator of G-protein signaling 16 0.0688 0.065
NPY NPY: Neuropeptide Y precursor [Contains: Neuropeptide Y 0.0688 0.072
PAEP PAEP: Glycodelin precursor 0.0688 0.081
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.0688 0.072
GHRL GHRL, MTLRP, UNQ524/PRO1066: Appetite-regulating hormone precursor 0.0688 0.109
RGS4 RGS4: Regulator of G-protein signaling 4 0.0688 0.100
CORT CORT, UNQ307/PRO350: Cortistatin precursor [Contains: Cortistatin-29; Cortistati 0.0688 0.081
INS INS: Insulin precursor [Contains: Insulin B chain; Insulin A chain] 0.0688 0.072
C8G C8G: Complement component C8 gamma chain precursor 0.0688 0.072
EDN1 EDN1: Endothelin-1 precursor 0.0688 0.202
ORM2 ORM2, AGP2: Alpha-1-acid glycoprotein 2 precursor 0.0688 0.072
APOM APOM, G3A, HSPC336, NG20: Apolipoprotein M 0.0688 0.072
C3 0.0688 0.072
AGT AGT, SERPINA8: Angiotensinogen precursor 0.0688 0.072
AMBP AMBP, HCP, ITIL: AMBP protein precursor [Contains: Alpha-1-microglobulin 0.0688 0.072
HTR2C HTR2C, HTR1C: 5-hydroxytryptamine receptor 2C 0.062 0.109
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.062 0.065
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.062 0.081
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.062 0.100
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.062 0.109
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.062 0.072
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.062 0.100
PMP2 PMP2: Myelin P2 protein 0.062 0.072
FRG1 FRG1: Protein FRG1 0.062 0.100
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.062 0.081
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.062 0.072
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.062 0.081
C5 C5: Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 a 0.051 0.051
C4B C4B: Complement C4-B precursor 0.051 0.051
OXT OXT, OT: Oxytocin-neurophysin 1 precursor 0.051 0.0338
AVP N/A 0.051 0.0338
POMC POMC: Corticotropin-lipotropin precursor 0.051 0.0338
SI SI: Sucrase-isomaltase, intestinal [Contains: Sucrase 0.047 0.029
ARRB1 ARRB1, ARR1: Beta-arrestin-1 0.046 0.051
ARRB2 N/A 0.046 0.0338
EPB41 EPB41, E41P: Protein 4.1 0.046 0.051
RGS7 RGS7: Regulator of G-protein signaling 7 0.046 0.0338
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.044 0.025
IL8RB IL8RB, CXCR2: High affinity interleukin-8 receptor B 0.034 0.062
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.034 0.037
CCR5 CCR5: CCR5 receptor (Fragment) 0.034 0.062
C1R C1R: Complement C1r subcomponent precursor 0.034 0.081
A2M A2M, FWP007: Alpha-2-macroglobulin precursor 0.034 0.029
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.034 0.027
RHO RHO, OPN2: Rhodopsin 0.034 0.055
F7 F7: Coagulation factor VII precursor 0.034 0.096
EDG1 EDG1: Sphingosine 1-phosphate receptor Edg-1 0.034 0.062
FPRL1 FPRL1, FPR2, FPRH1, LXA4R: FMLP-related receptor I 0.034 0.055
NF2 NF2, SCH: Merlin 0.034 0.049
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.034 0.123
HTR6 HTR6: 5-hydroxytryptamine receptor 6 0.034 0.062
F2RL1 F2RL1, GPR11, PAR2: Proteinase-activated receptor 2 precursor 0.034 0.096
F9 F9: Coagulation factor IX precursor 0.034 0.088
C2 C2: Complement C2 precursor 0.034 0.072
PCOLCE PCOLCE, PCPE1: Procollagen C-endopeptidase enhancer 1 precursor 0.034 0.0453
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.034 0.055
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.034 0.028
AZU1 AZU1: Azurocidin precursor 0.034 0.072
FPR1 FPR1: fMet-Leu-Phe receptor 0.034 0.055
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.034 0.032
PROZ PROZ: Vitamin K-dependent protein Z precursor 0.034 0.110
CTGF CTGF, CCN2, HCS24: Connective tissue growth factor precursor 0.034 0.124
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.034 0.028
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.034 0.057
F10 F10: Coagulation factor X precursor 0.034 0.115
PROS1 PROS1, PROS: Vitamin K-dependent protein S precursor 0.034 0.146
ELA3B ELA3B: Elastase-3B precursor 0.034 0.072
PZP PZP: Pregnancy zone protein precursor 0.034 0.057
GPR23 LPA4, GPR23, P2RY9: Lysophosphatidic acid receptor 4 0.034 0.077
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.034 0.083
PRSS22 PRSS22, BSSP4, SP001LA, PRSS26, UNQ302/PRO343: Brain-specific serine protease 4 0.034 0.072
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.034 0.037
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.034 0.062
MC4R MC4R: Melanocortin receptor 4 0.034 0.155
F2RL2 F2RL2, PAR3: Proteinase-activated receptor 3 precursor 0.034 0.077
KLK1 KLK1: Kallikrein-1 precursor 0.034 0.072
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.034 0.057
MUC2 MUC2, SMUC: Mucin-2 precursor 0.034 0.037
ELA2 ELA2: Leukocyte elastase precursor 0.034 0.081
DRD1 DRD1: D(1A) dopamine receptor 0.034 0.055
CMA1 CMA1, CYH, CYM: Chymase precursor 0.034 0.072
KCNJ1 KCNJ1, ROMK1: ATP-sensitive inward rectifier potassium channel 1 0.034 0.055
P2RY4 P2RY4, NRU: P2Y purinoceptor 4 0.034 0.096
STAT2 STAT2: Signal transducer and activator of transcription 2 0.034 0.025
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.034 0.083
F12 F12: Coagulation factor XII precursor 0.034 0.072
F11 F11: Coagulation factor XI precursor 0.034 0.109
ROCK1 ROCK1: Rho-associated protein kinase 1 0.034 0.0453
KLK3 KLK3, APS: Prostate-specific antigen precursor 0.034 0.109
CTSG CTSG: Cathepsin G precursor 0.034 0.072
C5AR1 C5AR1, C5AR, C5R1: C5a anaphylatoxin chemotactic receptor 0.034 0.055
PRTN3 PRTN3, MBN: Myeloblastin precursor 0.034 0.081
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.034 0.049
KCNJ3 KCNJ3, GIRK1: G protein-activated inward rectifier potassium channel 1 0.034 0.055
PLAT PLAT: Tissue-type plasminogen activator precursor 0.034 0.109
NDP NDP: Norrin precursor 0.034 0.032
HGFAC HGFAC: Hepatocyte growth factor activator precursor 0.034 0.109
CFI CFI, IF: Complement factor I precursor 0.034 0.081
GAB1 GAB1: GRB2-associated-binding protein 1 0.034 0.027
KLK6 KLK6, PRSS18, PRSS9: Kallikrein-6 precursor 0.034 0.072
TBXA2R TBXA2R: Thromboxane A2 receptor 0.034 0.083
F2RL3 F2RL3, PAR4: Proteinase-activated receptor 4 precursor 0.034 0.077
HP HP: Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta c 0.034 0.072
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.034 0.083
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.034 0.062
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.034 0.152
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.034 0.037
GZMB Endogenous granzyme B 0.034 0.100
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.034 0.062
CFB CFB, BF, BFD: Complement factor B precursor 0.034 0.072
JAK1 0.034 0.057
PROC PROC: Vitamin K-dependent protein C precursor 0.034 0.063
PRSS1 PRSS1, TRP1, TRY1, TRYP1: Trypsin-1 precursor 0.034 0.072
DRD2 DRD2: D(2) dopamine receptor 0.034 0.083
FLNA FLNA, FLN, FLN1: Filamin-A 0.034 0.057
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.034 0.037
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.034 0.055
F2 F2: Prothrombin precursor 0.034 0.063
CGA CGA: Glycoprotein hormones alpha chain precursor 0.034 0.032
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.034 0.037
C1S C1S: Complement C1s subcomponent precursor 0.034 0.081
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.034 0.049
TACR2 TACR2, NK2R, NKNAR, TAC2R: Substance-K receptor 0.030 0.055
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.030 0.034
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.030 0.0453
FNTB FNTB: Protein farnesyltransferase subunit beta 0.030 0.029
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.030 0.032
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.030 0.049
TSHR N/A 0.030 0.062
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.030 0.029
KCNJ12 KCNJ12, IRK2, KCNJN1: ATP-sensitive inward rectifier potassium channel 12 0.030 0.049
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.030 0.0453
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.030 0.030
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.030 0.037
STAT6 STAT6: Signal transducer and activator of transcription 6 0.030 0.0453
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.030 0.049
STAT3 0.030 0.049
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.030 0.075
CHRM2 CHRM2: Muscarinic acetylcholine receptor M2 0.030 0.062
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.030 0.049
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.030 0.037
TLN1 TLN1: Uncharacterized protein TLN1 0.030 0.075
TLN2 TLN2: Uncharacterized protein TLN2 0.030 0.029
TIMP1 TIMP1, CLGI, TIMP: Metalloproteinase inhibitor 1 precursor 0.030 0.091
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.030 0.026
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.030 0.032
RPS6KB1 N/A 0.030 0.057
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.030 0.0453
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.030 0.037
SFRP1 CDNA FLJ45402 fis, clone BRHIP3029409, moderately similar to Homo sapiens secret 0.030 0.077
PLG PLG: Plasminogen precursor 0.030 0.072
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.030 0.096
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.030 0.057
SSTR3 SSTR3: Somatostatin receptor type 3 0.030 0.062
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.030 0.037
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.030 0.049
RDX RDX: Radixin 0.030 0.0453
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.030 0.037
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.030 0.049
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.030 0.165
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.030 0.049
VIL2 N/A 0.030 0.037
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.030 0.027
MSN MSN: Moesin 0.030 0.057
OR10H3 OR10H3: Olfactory receptor 10H3 0.030 0.077
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.030 0.027
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.030 0.049
LPA LPA: Apolipoprotein(a) precursor 0.030 0.100
STAT4 STAT4: Signal transducer and activator of transcription 4 0.030 0.031
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.030 0.026
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.030 0.049
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.030 0.025
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.030 0.037
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.030 0.04
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.030 0.037
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.030 0.037
TRHR TRHR: Thyrotropin-releasing hormone receptor 0.030 0.062
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.030 0.057
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.030 0.0453
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.030 0.096
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.030 0.037
TMPRSS9 N/A 0.030 0.165
NULL Neutrophil-activating protein 4 (Fragment) 0.0288 0.0288
GNAS N/A 0.0288 0.0288
CXCL14 CXCL14, NJAC, UNQ240/PRO273, SCYB14: Small-inducible cytokine B14 precursor 0.0288 0.0288
GNAS Mutant guanine nucleotide-binding protein G(S), alpha subunit 0.0288 0.0288
GNAS N/A 0.0288 0.0288
GNAS GSA: Alpha subunit of GsGTP binding protein (Fragment) 0.0288 0.0288
NULL N/A 0.0288 0.0288
GNAS N/A 0.0288 0.0288
GNAS Guanine nucleotide-binding protein Gs alpha subunit isoform L2 0.0288 0.0288
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.028
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.028 0.032
ROS1 N/A 0.025 0.026
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.025 0.032
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.025 0.028
NCSTN NCSTN, KIAA0253, UNQ1874/PRO4317: Nicastrin precursor 0.025 0.026
0.228
Total Score 3.07