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The Barton Group

Predicted interactions involving protein CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL (IPI00027269) that score above 12.5

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
CBL ZAP70 ZAP70: Uncharacterized protein ZAP70 6.35E4 Evidence O
CBL FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 4.90E4 Evidence
CBL PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 3.15E4 Evidence
CBL KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 1.58E4 Evidence
CBL NCK2 NCK2: Cytoplasmic protein NCK2 7.06E3 Evidence
CBL GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 1.91E3 Evidence
CBL SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 824.0 Evidence
CBL YWHAB YWHAB: 14-3-3 protein beta/alpha 401.0 Evidence
CBL GRAP GRAP: GRB2-related adapter protein 296.0 Evidence
CBL FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 200.0 Evidence O
CBL SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 156.0 Evidence
CBL JAK2 JAK2: Tyrosine-protein kinase JAK2 149.0 Evidence
CBL SHC4 SHC-transforming protein 4 149.0 Evidence
CBL TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 132.0 Evidence
CBL PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 121.0 Evidence
CBL TESK1 TESK1: Dual specificity testis-specific protein kinase 1 109.0 Evidence
CBL LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 101.0 Evidence O
CBL SYK SYK: Tyrosine-protein kinase SYK 96.50 Evidence
CBL TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 90.80 Evidence
CBL ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 89.30 Evidence
CBL BMX N/A 89.30 Evidence
CBL INSL3 JAK3: Tyrosine-protein kinase JAK3 82.10 Evidence
CBL YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 80.00 Evidence
CBL JAK1 80.00 Evidence
CBL ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 79.90 Evidence O
CBL BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 78.20 Evidence O
CBL CSK CSK: Tyrosine-protein kinase CSK 78.20 Evidence O
CBL LYN LYN: Tyrosine-protein kinase Lyn 78.20 Evidence
CBL CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 72.70 Evidence O
CBL KIT KIT: Mast/stem cell growth factor receptor precursor 72.70 Evidence
CBL INSR INSR: Insulin receptor precursor 72.70 Evidence
CBL EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 67.1 Evidence
CBL PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 65.6 Evidence
CBL FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 59.60 Evidence O
CBL HCK N/A 59.60 Evidence O
CBL ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 57.70 Evidence
CBL TXK TXK, PTK4: Tyrosine-protein kinase TXK 52.50 Evidence
CBL FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 49.10 Evidence
CBL FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 49.10 Evidence
CBL AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 49.10 Evidence
CBL RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 44.00 Evidence O
CBL EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 40.50 Evidence
CBL EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 40.50 Evidence
CBL FLT3 FLT3, STK1: FL cytokine receptor precursor 40.50 Evidence
CBL ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 37.90 Evidence
CBL SORBS3 SORBS3, SCAM1: Vinexin 37.40 Evidence
CBL MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 36.60 Evidence
CBL MET MET: Hepatocyte growth factor receptor precursor 36.60 Evidence
CBL STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 33.90 Evidence
CBL EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 32.80 Evidence
CBL MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 32.80 Evidence
CBL SOS1 SOS1: Son of sevenless homolog 1 31.20 Evidence
CBL TEK TEK, TIE2: Angiopoietin-1 receptor precursor 29.10 Evidence
CBL IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 28.90 Evidence
CBL DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 28.20 Evidence
CBL PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 24.90 Evidence
CBL RASA1 RASA1, RASA: Ras GTPase-activating protein 1 22.30 Evidence
CBL STAT5B STAT5B: Signal transducer and activator of transcription 5B 22.20 Evidence
CBL PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 20.50 Evidence O
CBL WASPIP N/A 16.60 Evidence
CBL NCK1 NCK1, NCK: Cytoplasmic protein NCK1 16.60 Evidence O
CBL SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 16.40 Evidence
CBL RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 15.30 Evidence
CBL LNK SH2B3, LNK: SH2B adapter protein 3 15.10 Evidence
CBL SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 15.10 Evidence
CBL LCP2 LCP2: Lymphocyte cytosolic protein 2 15.00 Evidence O
CBL GAB1 GAB1: GRB2-associated-binding protein 1 15.00 Evidence
CBL CRKL CRKL: Crk-like protein 14.60 Evidence O
CBL STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 14.60 Evidence
CBL IRS1 IRS1: Insulin receptor substrate 1 13.80 Evidence
CBL SCML2 SCML2: Sex comb on midleg-like protein 2 13.80 Evidence
CBL STAT3 13.50 Evidence
CBL TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 13.50 Evidence
CBL CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 13.50 Evidence
CBL H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 13.40 Evidence
CBL GSK3A GSK3A: Glycogen synthase kinase-3 alpha 13.2 Evidence
CBL PRKCE PRKCE, PKCE: Protein kinase C epsilon type 13.2 Evidence
CBL TYRO3 TYRO3, BYK, DTK, RSE, SKY: Tyrosine-protein kinase receptor TYRO3 precursor 12.80 Evidence
CBL KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 12.70 Evidence