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The Barton Group

Predicted interactions involving protein PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta (IPI00029702) that score above 1.0

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
PTK2B ZAP70 ZAP70: Uncharacterized protein ZAP70 268.0 Evidence
PTK2B TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 268.0 Evidence
PTK2B FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 268.0 Evidence
PTK2B JAK2 JAK2: Tyrosine-protein kinase JAK2 268.0 Evidence
PTK2B STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 268.0 Evidence
PTK2B STAT5B STAT5B: Signal transducer and activator of transcription 5B 200.0 Evidence
PTK2B STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 200.0 Evidence
PTK2B LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 156.0 Evidence
PTK2B TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 139.0 Evidence
PTK2B SYK SYK: Tyrosine-protein kinase SYK 139.0 Evidence
PTK2B CRKL CRKL: Crk-like protein 139.0 Evidence
PTK2B KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 125.0 Evidence
PTK2B CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 121.0 Evidence
PTK2B PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 119.0 Evidence
PTK2B SLA SLA, SLAP, SLAP1: SRC-like-adapter 119.0 Evidence
PTK2B LNK SH2B3, LNK: SH2B adapter protein 3 119.0 Evidence
PTK2B ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 119.0 Evidence
PTK2B INSL3 JAK3: Tyrosine-protein kinase JAK3 119.0 Evidence
PTK2B SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 119.0 Evidence
PTK2B SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 119.0 Evidence
PTK2B SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 119.0 Evidence
PTK2B SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 119.0 Evidence
PTK2B BLNK BLNK, BASH, SLP65: B-cell linker protein 119.0 Evidence
PTK2B LCP2 LCP2: Lymphocyte cytosolic protein 2 117.0 Evidence
PTK2B JAK1 106.0 Evidence
PTK2B LYN LYN: Tyrosine-protein kinase Lyn 106.0 Evidence
PTK2B GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 106.0 Evidence
PTK2B FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 106.0 Evidence
PTK2B FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 106.0 Evidence
PTK2B VAV1 VAV1, VAV: Proto-oncogene vav 106.0 Evidence
PTK2B CSK CSK: Tyrosine-protein kinase CSK 106.0 Evidence
PTK2B PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 106.0 Evidence
PTK2B ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 106.0 Evidence
PTK2B APS SH2B2, APS: SH2B adapter protein 2 106.0 Evidence
PTK2B STAT6 STAT6: Signal transducer and activator of transcription 6 106.0 Evidence
PTK2B BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 106.0 Evidence
PTK2B HCK N/A 106.0 Evidence
PTK2B STAT3 106.0 Evidence
PTK2B RASA1 RASA1, RASA: Ras GTPase-activating protein 1 106.0 Evidence
PTK2B CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 104.0 Evidence
PTK2B CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 89.20 Evidence
PTK2B GRB10 N/A 56.20 Evidence
PTK2B SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 32.90 Evidence
PTK2B GRAP GRAP: GRB2-related adapter protein 32.90 Evidence
PTK2B SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 31.60 Evidence
PTK2B PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 22.30 Evidence
PTK2B FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 22.30 Evidence
PTK2B KIT KIT: Mast/stem cell growth factor receptor precursor 22.30 Evidence
PTK2B CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 22.30 Evidence
PTK2B SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 21.50 Evidence
PTK2B SHB SHB: SH2 domain-containing adapter protein B 21.50 Evidence
PTK2B STAM2 STAM2: Signal transducing adapter molecule 2 20.50 Evidence
PTK2B CTTN CTTN, EMS1: Src substrate cortactin 15.00 Evidence
PTK2B IRS1 IRS1: Insulin receptor substrate 1 15.00 Evidence
PTK2B IRS2 IRS2: Insulin receptor substrate 2 15.00 Evidence
PTK2B EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 14.10 Evidence
PTK2B ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 13.50 Evidence
PTK2B ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 13.50 Evidence
PTK2B INSR INSR: Insulin receptor precursor 13.50 Evidence
PTK2B KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 13.50 Evidence
PTK2B DOK1 DOK1: Docking protein 1 13.40 Evidence
PTK2B WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 13.40 Evidence
PTK2B WASL WASL: Neural Wiskott-Aldrich syndrome protein 13.40 Evidence
PTK2B CD2AP CD2AP: CD2-associated protein 13.40 Evidence
PTK2B HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 13.40 Evidence
PTK2B TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 11.60 Evidence
PTK2B EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 11.60 Evidence
PTK2B PRKCE PRKCE, PKCE: Protein kinase C epsilon type 10.30 Evidence
PTK2B ACTG1 ACTB: Actin, cytoplasmic 1 10.30 Evidence
PTK2B IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 9.92 Evidence
PTK2B CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 9.92 Evidence
PTK2B IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 9.92 Evidence
PTK2B CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 9.92 Evidence
PTK2B CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 9.92 Evidence
PTK2B TEK TEK, TIE2: Angiopoietin-1 receptor precursor 9.92 Evidence
PTK2B CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 9.92 Evidence
PTK2B EPOR EPOR: Erythropoietin receptor precursor 9.92 Evidence
PTK2B TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 9.92 Evidence
PTK2B IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 9.92 Evidence
PTK2B AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 9.92 Evidence
PTK2B ITGB4 N/A 9.92 Evidence
PTK2B GHR GHR: Growth hormone receptor precursor 9.92 Evidence
PTK2B CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 9.92 Evidence
PTK2B MET MET: Hepatocyte growth factor receptor precursor 9.92 Evidence
PTK2B CXCR4 CXCR4: C-X-C chemokine receptor type 4 9.92 Evidence
PTK2B CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 9.92 Evidence
PTK2B PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 9.92 Evidence
PTK2B EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 8.89 Evidence
PTK2B RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 8.89 Evidence
PTK2B SOS1 SOS1: Son of sevenless homolog 1 8.89 Evidence
PTK2B MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 8.89 Evidence
PTK2B IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 8.89 Evidence
PTK2B EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 8.89 Evidence
PTK2B PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 8.89 Evidence
PTK2B EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 8.89 Evidence
PTK2B EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 8.55 Evidence
PTK2B SGK2 SGK2: Serine/threonine-protein kinase Sgk2 7.59 Evidence
PTK2B PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 6.80 Evidence
PTK2B PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 6.80 Evidence
PTK2B RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 6.80 Evidence
PTK2B BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 5.50 Evidence
PTK2B CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 4.68 Evidence
PTK2B PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 4.68 Evidence
PTK2B FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 4.48 Evidence
PTK2B LAT LAT: Linker for activation of T-cells family member 1 4.48 Evidence
PTK2B ADAM15 ADAM15, MDC15: ADAM 15 precursor 4.48 Evidence
PTK2B CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 4.48 Evidence
PTK2B FIGF FIGF, VEGFD: Vascular endothelial growth factor D precursor 4.19 Evidence
PTK2B RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 3.47 Evidence
PTK2B EFNA1 EFNA1, EPLG1, LERK1, TNFAIP4: Ephrin-A1 precursor 3.02 Evidence
PTK2B SCAP2 SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2 2.43 Evidence
PTK2B CDC23 CDC23: Cell division cycle protein 23 homolog 2.28 Evidence
PTK2B SHC1 SHC1, RP11-307C12.1-001, hCG_1997126: SHC 2.28 Evidence
PTK2B CASP3 CASP3, CPP32: Caspase-3 precursor 2.28 Evidence
PTK2B BCR N/A 2.28 Evidence
PTK2B PTPN11 N/A 2.28 Evidence
PTK2B HNRPK N/A 2.28 Evidence
PTK2B TYRO3 TYRO3, BYK, DTK, RSE, SKY: Tyrosine-protein kinase receptor TYRO3 precursor 1.91 Evidence
PTK2B ACTB ACTG1, ACTB, ACTG: Actin, cytoplasmic 2 1.74 Evidence
PTK2B EFNA5 EFNA5, EPLG7, LERK7: Ephrin-A5 precursor 1.27 Evidence
PTK2B GNAI2 Galphai2 protein 1.16 Evidence
PTK2B GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 1.13 Evidence
PTK2B PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 1.13 Evidence
PTK2B MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 1.13 Evidence
PTK2B BMX N/A 1.13 Evidence
PTK2B SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 1.13 Evidence
PTK2B PTK6 PTK6, BRK: Tyrosine-protein kinase 6 1.13 Evidence
PTK2B ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 1.13 Evidence
PTK2B FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 1.01 Evidence
PTK2B NCK2 NCK2: Cytoplasmic protein NCK2 1.01 Evidence
PTK2B YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 1.01 Evidence
PTK2B RIN1 RIN1: Ras and Rab interactor 1 1.01 Evidence
PTK2B TXK TXK, PTK4: Tyrosine-protein kinase TXK 1.01 Evidence
PTK2B NCK1 NCK1, NCK: Cytoplasmic protein NCK1 1.01 Evidence