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The Barton Group

Predicted interactions involving protein SH2B2, APS: SH2B adapter protein 2 (IPI00155706) that score above 2.5

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
APS TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 407.0 Evidence
APS CSK CSK: Tyrosine-protein kinase CSK 268.0 Evidence
APS FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 268.0 Evidence
APS JAK2 JAK2: Tyrosine-protein kinase JAK2 200.0 Evidence
APS BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 198.0 Evidence
APS LYN LYN: Tyrosine-protein kinase Lyn 180.0 Evidence
APS ZAP70 ZAP70: Uncharacterized protein ZAP70 176.0 Evidence
APS FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 162.0 Evidence
APS TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 161.0 Evidence
APS FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 149.0 Evidence
APS CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 149.0 Evidence
APS SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 137.0 Evidence
APS PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 134.0 Evidence
APS KIT KIT: Mast/stem cell growth factor receptor precursor 132.0 Evidence
APS SYK SYK: Tyrosine-protein kinase SYK 128.0 Evidence
APS PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 119.0 Evidence
APS ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 106.0 Evidence
APS PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 106.0 Evidence
APS ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 88.80 Evidence
APS LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 88.80 Evidence
APS BMX N/A 88.80 Evidence
APS KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 80.00 Evidence
APS INSR INSR: Insulin receptor precursor 80.00 Evidence
APS HCK N/A 79.50 Evidence
APS JAK1 79.50 Evidence
APS YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 79.40 Evidence
APS EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 73.60 Evidence
APS TEK TEK, TIE2: Angiopoietin-1 receptor precursor 52.80 Evidence
APS NCK2 NCK2: Cytoplasmic protein NCK2 39.10 Evidence
APS CRKL CRKL: Crk-like protein 31.20 Evidence
APS KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 25.90 Evidence
APS STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 25.3 Evidence
APS PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 25.3 Evidence
APS CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 24.90 Evidence
APS BLNK BLNK, BASH, SLP65: B-cell linker protein 22.80 Evidence
APS STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 22.30 Evidence
APS STAT5B STAT5B: Signal transducer and activator of transcription 5B 20.50 Evidence
APS SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 20.50 Evidence
APS GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 20.50 Evidence
APS WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 20.40 Evidence
APS STAT3 19.70 Evidence
APS NCK1 NCK1, NCK: Cytoplasmic protein NCK1 18.90 Evidence
APS SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 17.30 Evidence
APS PRKCE PRKCE, PKCE: Protein kinase C epsilon type 16.20 Evidence
APS STAT6 STAT6: Signal transducer and activator of transcription 6 15.50 Evidence
APS VAV1 VAV1, VAV: Proto-oncogene vav 15.50 Evidence
APS HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 15.50 Evidence
APS STAM2 STAM2: Signal transducing adapter molecule 2 15.30 Evidence
APS PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 15.00 Evidence
APS LNK SH2B3, LNK: SH2B adapter protein 3 15.00 Evidence
APS SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 13.80 Evidence
APS PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 13.50 Evidence
APS RASA1 RASA1, RASA: Ras GTPase-activating protein 1 13.40 Evidence
APS DOK1 DOK1: Docking protein 1 12.40 Evidence
APS PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 12.40 Evidence
APS STAT2 STAT2: Signal transducer and activator of transcription 2 11.40 Evidence
APS CXCR4 CXCR4: C-X-C chemokine receptor type 4 11.40 Evidence
APS SLA SLA, SLAP, SLAP1: SRC-like-adapter 11.20 Evidence
APS IRS1 IRS1: Insulin receptor substrate 1 11.20 Evidence
APS SOS1 SOS1: Son of sevenless homolog 1 10.70 Evidence
APS CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 10.70 Evidence
APS CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 10.10 Evidence
APS PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 10.00 Evidence
APS WASL WASL: Neural Wiskott-Aldrich syndrome protein 10.00 Evidence
APS PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 9.92 Evidence
APS CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 9.92 Evidence
APS IRS2 IRS2: Insulin receptor substrate 2 9.89 Evidence
APS CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 9.14 Evidence
APS IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 9.14 Evidence
APS CTTN CTTN, EMS1: Src substrate cortactin 8.92 Evidence
APS CREBBP CREBBP, CBP: CREB-binding protein 8.00 Evidence
APS NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 7.85 Evidence
APS SNCA SNCA, NACP, PARK1: Alpha-synuclein 7.59 Evidence
APS IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 7.40 Evidence
APS SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 6.78 Evidence
APS ITGB4 N/A 6.52 Evidence
APS LCP2 LCP2: Lymphocyte cytosolic protein 2 6.52 Evidence
APS IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 6.52 Evidence
APS GRAP GRAP: GRB2-related adapter protein 6.31 Evidence
APS EPOR EPOR: Erythropoietin receptor precursor 5.88 Evidence
APS BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 5.50 Evidence
APS DAPP1 N/A 4.73 Evidence
APS KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 4.68 Evidence
APS DNM1 DNM1, DNM: Dynamin-1 4.68 Evidence
APS GRB10 N/A 4.68 Evidence
APS CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 4.31 Evidence
APS CD19 N/A 4.06 Evidence
APS YWHAB YWHAB: 14-3-3 protein beta/alpha 3.93 Evidence
APS PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 3.49 Evidence
APS CASP3 CASP3, CPP32: Caspase-3 precursor 2.63 Evidence