Predicted interactions involving protein MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 (IPI00219604) that score above 12.5

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
MAP2K1 BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 6.08E3 Evidence O
MAP2K1 RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 3.26E3 Evidence O
MAP2K1 AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 32.80 Evidence
MAP2K1 DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 31.20 Evidence
MAP2K1 SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 30.00 Evidence
MAP2K1 DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 27.80 Evidence
MAP2K1 MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 27.80 Evidence O
MAP2K1 JAK2 JAK2: Tyrosine-protein kinase JAK2 25.00 Evidence
MAP2K1 VAV1 VAV1, VAV: Proto-oncogene vav 25.00 Evidence
MAP2K1 STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 23.70 Evidence
MAP2K1 DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 20.50 Evidence
MAP2K1 JAK1 20.50 Evidence
MAP2K1 PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 20.40 Evidence
MAP2K1 NRAS NRAS, HRAS1: GTPase NRas precursor 20.20 Evidence
MAP2K1 YWHAB YWHAB: 14-3-3 protein beta/alpha 17.90 Evidence
MAP2K1 CDC25A CDC25A: M-phase inducer phosphatase 1 17.60 Evidence
MAP2K1 DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 17.60 Evidence
MAP2K1 PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 17.60 Evidence
MAP2K1 SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 17.60 Evidence
MAP2K1 PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 17.60 Evidence
MAP2K1 LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 17.30 Evidence
MAP2K1 SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 17.30 Evidence
MAP2K1 IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 16.50 Evidence
MAP2K1 HSP90AA1 Hsp89-alpha-delta-N 16.50 Evidence
MAP2K1 MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 15.70 Evidence O
MAP2K1 YWHAZ YWHAZ: 14-3-3 protein zeta/delta 15.40 Evidence
MAP2K1 FRS3 FRS3: Fibroblast growth factor receptor substrate 3 15.30 Evidence
MAP2K1 RB1 RB1: Retinoblastoma-associated protein 15.10 Evidence
MAP2K1 CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 15.10 Evidence
MAP2K1 DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 13.80 Evidence
MAP2K1 FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 13.40 Evidence