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The Barton Group

Predicted interactions involving protein PRKACA, PKACA: cAMP-dependent protein kinase catalytic subunit alpha (IPI00396630) that score above 0.125

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
PRKACA RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 20.50 Evidence
PRKACA JAK2 JAK2: Tyrosine-protein kinase JAK2 17.60 Evidence
PRKACA CDC25A CDC25A: M-phase inducer phosphatase 1 17.60 Evidence
PRKACA JUNB JUNB: Transcription factor jun-B 17.10 Evidence
PRKACA JUN JUN: Transcription factor AP-1 17.10 Evidence
PRKACA ZAP70 ZAP70: Uncharacterized protein ZAP70 13.40 Evidence
PRKACA GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 11.60 Evidence
PRKACA NRAS NRAS, HRAS1: GTPase NRas precursor 10.30 Evidence
PRKACA MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 8.92 Evidence
PRKACA PRKCE PRKCE, PKCE: Protein kinase C epsilon type 8.92 Evidence
PRKACA GIT2 N/A 8.92 Evidence
PRKACA PRKAR2A PRKAR2A, PKR2, PRKAR2: cAMP-dependent protein kinase type II-alpha regulatory su 6.93 Evidence
PRKACA PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 6.80 Evidence
PRKACA PRKCG PRKCG, PKCG: Protein kinase C gamma type 6.80 Evidence
PRKACA SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 6.80 Evidence
PRKACA CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 5.74 Evidence
PRKACA MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 5.73 Evidence
PRKACA PRKAR1A PRKAR1A, PKR1, PRKAR1, TSE1: cAMP-dependent protein kinase type I-alpha regulato 4.84 Evidence
PRKACA MCM3 MCM3: DNA replication licensing factor MCM3 4.26 Evidence
PRKACA NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 4.26 Evidence
PRKACA PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 3.65 Evidence
PRKACA CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 3.47 Evidence
PRKACA YWHAB YWHAB: 14-3-3 protein beta/alpha 3.47 Evidence
PRKACA GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 3.44 Evidence
PRKACA CDK4 CDK4: Cell division protein kinase 4 2.99 Evidence
PRKACA ACTG1 ACTB: Actin, cytoplasmic 1 2.99 Evidence
PRKACA MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 2.99 Evidence
PRKACA HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 2.99 Evidence
PRKACA DLG1 N/A 2.28 Evidence
PRKACA SGK2 SGK2: Serine/threonine-protein kinase Sgk2 2.28 Evidence
PRKACA SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 2.28 Evidence
PRKACA MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 2.28 Evidence
PRKACA JUP JUP, CTNNG, DP3: Junction plakoglobin 2.28 Evidence
PRKACA CCNE2 CCNE2: G1/S-specific cyclin-E2 2.17 Evidence
PRKACA PRKAR2B N/A 1.39 Evidence
PRKACA INSR INSR: Insulin receptor precursor 1.16 Evidence
PRKACA COPB2 COPB2: Coatomer subunit beta' 1.15 Evidence
PRKACA PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 1.15 Evidence
PRKACA CNOT3 CNOT3, KIAA0691, LENG2, NOT3: CCR4-NOT transcription complex subunit 3 1.0 Evidence
PRKACA RAB7 RAB7A, RAB7: Ras-related protein Rab-7a 0.905 Evidence
PRKACA RAB5A RAB5A, RAB5: Ras-related protein Rab-5A 0.36 Evidence
PRKACA SURF5 N/A 0.36 Evidence
PRKACA STX1A STX1A, STX1: Syntaxin-1A 0.318 Evidence
PRKACA CKS1B CKS1B, CKS1, PNAS-16, PNAS-143: Cyclin-dependent kinases regulatory subunit 1 0.268 Evidence
PRKACA TCP1 CCT1, CCTA, TCP1: T-complex protein 1 subunit alpha 0.202 Evidence
PRKACA PYGL PYGL: Glycogen phosphorylase, liver form 0.2 Evidence
PRKACA RPA1 RPA1, REPA1, RPA70: Replication protein A 70 kDa DNA-binding subunit 0.16 Evidence
PRKACA HSPE1 HSPE1: 10 kDa heat shock protein, mitochondrial 0.148 Evidence
PRKACA BRSK1 BRSK1, KIAA1811, SAD1: BR serine/threonine-protein kinase 1 0.142 Evidence
PRKACA SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.142 Evidence
PRKACA MCF2 MCF2, DBL: Proto-oncogene DBL 0.142 Evidence
PRKACA PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.142 Evidence
PRKACA INSL3 JAK3: Tyrosine-protein kinase JAK3 0.142 Evidence
PRKACA SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.142 Evidence
PRKACA GAB2 N/A 0.142 Evidence
PRKACA PSCD1 PSCD1, D17S811E: Cytohesin-1 0.142 Evidence
PRKACA IRS1 IRS1: Insulin receptor substrate 1 0.142 Evidence
PRKACA IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.142 Evidence
PRKACA STAT2 STAT2: Signal transducer and activator of transcription 2 0.142 Evidence
PRKACA OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.142 Evidence
PRKACA PLEK PLEK, P47: Pleckstrin 0.142 Evidence
PRKACA DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.142 Evidence
PRKACA HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.142 Evidence
PRKACA SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.142 Evidence
PRKACA SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.142 Evidence
PRKACA ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.142 Evidence
PRKACA ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.142 Evidence
PRKACA HMGA2 HMGA2, HMGIC: High mobility group protein HMGI-C 0.142 Evidence
PRKACA PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.142 Evidence
PRKACA LNK SH2B3, LNK: SH2B adapter protein 3 0.142 Evidence
PRKACA APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.142 Evidence
PRKACA BMX N/A 0.142 Evidence
PRKACA ROCK1 ROCK1: Rho-associated protein kinase 1 0.142 Evidence
PRKACA ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.142 Evidence
PRKACA PSCD2 N/A 0.142 Evidence
PRKACA CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.142 Evidence
PRKACA SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.142 Evidence
PRKACA ETV1 ETV1, ER81: ETS translocation variant 1 0.142 Evidence
PRKACA SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.142 Evidence
PRKACA LCP2 LCP2: Lymphocyte cytosolic protein 2 0.142 Evidence
PRKACA NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.142 Evidence
PRKACA LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.142 Evidence
PRKACA SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.142 Evidence
PRKACA HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.142 Evidence
PRKACA PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.142 Evidence
PRKACA MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.142 Evidence
PRKACA GAB1 GAB1: GRB2-associated-binding protein 1 0.142 Evidence
PRKACA SNCB SNCB: Beta-synuclein 0.142 Evidence
PRKACA DNM3 DNM3: Uncharacterized protein DNM3 0.142 Evidence
PRKACA SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.142 Evidence
PRKACA VASP VASP: Vasodilator-stimulated phosphoprotein 0.142 Evidence
PRKACA NSBP1 NSBP1: Nucleosome-binding protein 1 0.142 Evidence
PRKACA MAP2K5 N/A 0.142 Evidence
PRKACA ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.142 Evidence
PRKACA IRS2 IRS2: Insulin receptor substrate 2 0.142 Evidence
PRKACA SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.142 Evidence
PRKACA HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.142 Evidence
PRKACA NF2 NF2, SCH: Merlin 0.142 Evidence
PRKACA PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.142 Evidence
PRKACA BLNK BLNK, BASH, SLP65: B-cell linker protein 0.142 Evidence
PRKACA PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.128 Evidence
PRKACA TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.128 Evidence
PRKACA PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.128 Evidence
PRKACA DOK1 DOK1: Docking protein 1 0.128 Evidence
PRKACA APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.128 Evidence
PRKACA ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.128 Evidence
PRKACA MSN MSN: Moesin 0.128 Evidence
PRKACA PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.128 Evidence
PRKACA DAB2 DAB2, DOC2: Disabled homolog 2 0.128 Evidence
PRKACA CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.128 Evidence
PRKACA STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.128 Evidence
PRKACA PSCD4 PSCD4, CYT4: Cytohesin-4 0.128 Evidence
PRKACA STAT3 0.128 Evidence
PRKACA VAV1 VAV1, VAV: Proto-oncogene vav 0.128 Evidence
PRKACA CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.128 Evidence
PRKACA SYK SYK: Tyrosine-protein kinase SYK 0.128 Evidence
PRKACA STAT4 STAT4: Signal transducer and activator of transcription 4 0.128 Evidence
PRKACA SH3BP5 N/A 0.128 Evidence
PRKACA APS SH2B2, APS: SH2B adapter protein 2 0.128 Evidence
PRKACA RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.128 Evidence
PRKACA TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.128 Evidence
PRKACA TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.128 Evidence
PRKACA PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.128 Evidence
PRKACA RIN1 RIN1: Ras and Rab interactor 1 0.128 Evidence
PRKACA DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.128 Evidence
PRKACA MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.128 Evidence
PRKACA YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.128 Evidence
PRKACA ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.128 Evidence
PRKACA ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.128 Evidence
PRKACA STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.128 Evidence
PRKACA SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.128 Evidence
PRKACA PLD1 PLD1: Phospholipase D1 0.128 Evidence
PRKACA CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.128 Evidence
PRKACA LYN LYN: Tyrosine-protein kinase Lyn 0.128 Evidence
PRKACA EPB41L2 EPB41L2: Band 4.1-like protein 2 0.128 Evidence
PRKACA CREB1 CREB1: cAMP response element-binding protein 0.128 Evidence
PRKACA ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.128 Evidence
PRKACA CRKL CRKL: Crk-like protein 0.128 Evidence
PRKACA ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.128 Evidence
PRKACA CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.128 Evidence
PRKACA CCNB1 Cyclin B1 0.128 Evidence
PRKACA OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.128 Evidence
PRKACA BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.128 Evidence
PRKACA TST TST: Thiosulfate sulfurtransferase 0.128 Evidence
PRKACA DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.128 Evidence
PRKACA RDX RDX: Radixin 0.128 Evidence
PRKACA HCK N/A 0.128 Evidence
PRKACA STAT6 STAT6: Signal transducer and activator of transcription 6 0.128 Evidence
PRKACA STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.128 Evidence
PRKACA PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.128 Evidence
PRKACA SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.128 Evidence
PRKACA ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.128 Evidence
PRKACA DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.128 Evidence
PRKACA FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.128 Evidence
PRKACA NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.128 Evidence
PRKACA RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.128 Evidence
PRKACA GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.128 Evidence
PRKACA TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.128 Evidence
PRKACA CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.128 Evidence
PRKACA SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.128 Evidence
PRKACA PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.128 Evidence
PRKACA IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.128 Evidence
PRKACA PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.128 Evidence
PRKACA AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.128 Evidence
PRKACA FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.128 Evidence
PRKACA PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.128 Evidence
PRKACA SOS1 SOS1: Son of sevenless homolog 1 0.128 Evidence
PRKACA ARHGEF7 N/A 0.128 Evidence
PRKACA SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.128 Evidence
PRKACA PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.128 Evidence
PRKACA AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.128 Evidence
PRKACA JAK1 0.128 Evidence
PRKACA WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.128 Evidence
PRKACA DAB1 DAB1: Disabled homolog 1 0.128 Evidence
PRKACA FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.128 Evidence
PRKACA ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.128 Evidence
PRKACA PSMA5 PSMA5: Proteasome subunit alpha type-5 0.128 Evidence
PRKACA STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.128 Evidence
PRKACA CDC25C CDC25C: M-phase inducer phosphatase 3 0.128 Evidence
PRKACA NCK2 NCK2: Cytoplasmic protein NCK2 0.128 Evidence
PRKACA FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.128 Evidence
PRKACA PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.128 Evidence
PRKACA ELMO1 N/A 0.128 Evidence
PRKACA PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.128 Evidence
PRKACA PLD2 PLD2: Phospholipase D2 0.128 Evidence
PRKACA BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.128 Evidence
PRKACA CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.128 Evidence
PRKACA WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.128 Evidence
PRKACA ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.128 Evidence
PRKACA EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.128 Evidence
PRKACA EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.128 Evidence
PRKACA EEF2K EEF2K: Elongation factor 2 kinase 0.128 Evidence
PRKACA GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.128 Evidence
PRKACA DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.128 Evidence
PRKACA CCNH CCNH: Cyclin-H 0.128 Evidence
PRKACA PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.128 Evidence
PRKACA CCNT2 CCNT2: Cyclin-T2 0.128 Evidence
PRKACA FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.128 Evidence
PRKACA STMN1 STMN1, LAP18, OP18: Stathmin 0.128 Evidence
PRKACA CSK CSK: Tyrosine-protein kinase CSK 0.128 Evidence
PRKACA PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.128 Evidence
PRKACA ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.128 Evidence
PRKACA VIL2 N/A 0.128 Evidence
PRKACA CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.128 Evidence
PRKACA ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.128 Evidence
PRKACA RASA3 RASA3: Ras GTPase-activating protein 3 0.128 Evidence
PRKACA C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.128 Evidence
PRKACA PSD TYL: TYL protein 0.128 Evidence