Slivka is a free middleware which provides convenient remote access to computer programs installed on your local computer, a server, or a cluster.

This installation of slivka, maintained by the Barton Group in the Division of Computational Biology, at the School of Life Sciences, University of Dundee, offers web services that wrap a range of bioinformatic programs. These include multiple sequence alignment programs such as Clustal Omega, Clustal W, MAFFT, MUSCLE, T-Coffee, ProbCons and MSAProbs; protein disorder prediction tools: GlobPlot, DisEMBL, IUPred, Jronn (a Java implementation of Ronn by P. Troshin and G. Barton, unpublished). It also provides access to secondary structure predictions of proteins via JPred and calculation of amino acid alignment conservation with AACon.

Slivka-bio's web services are designed for easy programmatic access and interoperation. They can be employed with future version 2.12 of the Jalview interactive multiple sequence alignment workbench (via Jalview Desktop or JalviewJS), the Slivka Command Line Client, or directly through the REST API. You can perform computations on your sequences using our publicly available server running at the University of Dundee. Alternatively, you can install Slivka-bio on your local computer, server or cluster to take advantage of your own computing resources.