I am moving from the Barton Group, Computational Biology at the University of Dundee and will working at The Cancer Research UK, Manchester Institute. These pages are no longer maintained.

Publications

[1] N. J. Schurch, P. Schofield, M. Gierliński, C. Cole, A. Sherstnev, V. Singh, N. Wrobel, K. Gharbi, G. G. Simpson, T. Owen-Hughes, M. Blaxter and G. J. Barton. “How many biological replicates are needed in an RNA-seq experiment and which differential expression tool should you use?” In: RNA (Mar. 28, 2016). DOI: 10.1261/rna.053959.115. .

[2] N. Wiechens, V. Singh, T. Gkikopoulos, P. Schofield, S. Rocha and T. Owen-Hughes. “The Chromatin Remodelling Enzymes SNF2H and SNF2L Position Nucleosomes adjacent to CTCF and Other Transcription Factors.” In: PLoS genetics 12.3 (Mar. 2016), p. e1005940. ISSN: 1553-7404 1553-7390. DOI: 10.1371/journal.pgen.1005940. pmid: 27019336.

[3] M. Gierliński, C. Cole, P. Schofield, N. J. Schurch, A. Sherstnev, V. Singh, N. Wrobel, K. Gharbi, G. Simpson, T. Owen-Hughes, M. Blaxter and G. J. Barton. “Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment”. In: Bioinformatics (Jul. 2015).

[4] A. Seifert, P. Schofield, G. J. Barton and R. T. Hay. “Proteotoxic stress reprograms the chromatin landscape of SUMO modification”. In: Science Signalling 8.384 (2015).

[5] D. M. Roberts, P. G. Schofield, S. Donn and T. J. Daniell. “Directed terminal restriction analysis tool (DRAT): an aid to enzyme selection for directed terminal-restriction fragment length polymorphisms”. In: Methods in Ecology and Evolution 3 (2012), pp. 24-28.

[6] T. Gkikopoulos, P. Schofield, V. Singh, M. Pinskaya, J. Mellor, M. Smolle, J. L. Workman, G. J. Barton and T. Owen-Hughes. “A Role for Snf2-Related Nucleosome-Spacing Enzymes in Genome-Wide Nucleosome Organization”. In: Science 333 (2011), pp. 1758-1760.

[7] T. Gkikopoulos, V. Singh, K. Tsui, S. Awad, M. J. Renshaw, P. Scholfield, G. J. Barton, C. Nislow, T. U. Tanaka and T. Owen-Hughes. “The SWI/SNF complex acts to constrain distribution of the centromeric histone variant Cse4”. In: Embo Journal 30 (2011), pp. 1919-1927.

[8] S. van Koningsbruggen, M. Gierlinski, P. Schofield, D. Martin, G. J. Barton, Y. Ariyurek, J. T. den Dunnen and A. I. Lamond. “High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli”. In: Molecular Biology of the Cell 21 (2010), pp. 3735-3748.

[9] K. F. Preedy, P. G. Schofield, S. Liu, A. Matzavinos, M. A. J. Chaplain and S. F. Hubbard. “Modelling contact spread of infection in host-parasitoid systems: Vertical transmission of pathogens can cause chaos”. In: Journal of Theoretical Biology 262 (2010), pp. 441-451.

[10] B. Reed, S. Rhodes, P. Schofield and K. Wylie. “Gender Variance in the UK: Prevalence, incidence growth and geographic distribution.” In: GIRES Technical Report (2009).

[11] Jones H. G. and P. Schofield. “Thermal and Other Remote Sensing of Plant Stress.” In: General Applications Plant Physiology (2008).

[12] I. G. Pearce, M. A. J. Chaplain, P. G. Schofield, A. R. A. Anderson and S. F. Hubbard. “Chemotaxis-induced spatio-temporal heterogeneity in multi-species host-parasitoid systems”. In: Journal of Mathematical Biology 55 (2007), pp. 365-388.

[13] K. F. Preedy, P. G. Schofield, M. A. J. Chaplain and S. F. Hubbard. “Disease induced dynamics in host-parasitoid systems: chaos and coexistence”. In: Journal of the Royal Society Interface 4 (2007), pp. 463-471.

[14] A. Fytrou, P. G. Schofield, A. R. Kraaijeveld and S. F. Hubbard. “Wolbachia infection suppresses both host defence and parasitoid counter-defence”. In: Proceedings of the Royal Society B: Biological Sciences 273.1588 (2006), pp. 791-796.

[15] I. G. Pearce, M. A. J. Chaplain, P. G. Schofield, A. R. A. Anderson and S. F. Hubbard. “Modelling the spatio-temporal dynamics of multi-species host-parasitoid interactions: heterogeneous patterns and ecological implications.” In: J Theor Biol 241.4 (2006), pp. 876-886.

[16] P. G. Schofield, M. A. J. Chaplain and S. F. Hubbard. “Dynamic heterogeneous spatio-temporal pattern formation in host-parasitoid systems with synchronised generations.” In: J Math Biol 50.5 (2005), pp. 559-583.

[17] P. Schofield, M. Chaplain and S. Hubbard. “Evolution of searching and life history characteristics in individual-based models of host-parasitoid-microbe associations.” In: J Theor Biol 237.1 (2005), pp. 1-16.

[18] P. Schofield. “Spatially Explicit Models of Turelli-Hoffmann Wolbachia Invasive Wave Fronts”. In: Journal of Theoretical Biology 215.1 (2002), pp. 121-131.

[19] P. G. Schofield. “Spatio-temporal Mathematical Models for the Investigation of Host-Parasitoid Systems and Wolbachia-infection Dynamics”. PhD thesis. Dundee: University of Dundee, 2002.

[20] P. G. Schofield, M. A. J. Chaplain and S. F. Hubbard. “Mathematical modelling of host-parasitoid systems: Effects of chemically mediated parasitoid foraging strategies on within- and between-generation spatio-temporal dynamics”. In: J. Theor. Biol. 214 (2002), pp. 31-47.

[21] P. Schofield, M. Chaplain and S. F. Hubbard. “Spatio-temporal mathematical models of host-parasitoid systems”. In: European Communications of Mathematical and Theoretical Biology 2.12-17 (2000).