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Evidence of Interaction Between F2 and PLG

The interaction score between F2 and PLG is 1.89E5.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between F2 and PLG = 0.85

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 0.027
Orthology
OrganismF2 OrthologuePLG OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00019576 0.121 IPI00019590 0.057
  • InVitro

Get References From PubMed
human IPI00019576 0.121 IPI00029168 0.515
human IPI00019576 0.121 IPI00025767 0.183
human IPI00019576 0.121 IPI00555830 0.191
human IPI00019576 0.121 IPI00385782 0.131
fly Q9VBY4 0.121 Q9V516 0.086
fly Q9VBY4 0.121 Q9V517 1
fly Q9VBY4 0.121 Q9V519 0.083

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 1.07
Domains Domains present in F2 and PLG:
Domains in F2Domains in PLG
IPR000001 Kringle
IPR001254 Peptidase S1, chymotrypsin
IPR001314 Peptidase S1A, chymotrypsin
IPR009003 Peptidase, trypsin-like serine and cysteine proteases
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region
IPR002383 Coagulation factor, Gla region
IPR003966 Peptidase S1A, prothrombin
IPR012051 Thrombin.
IPR000001 Kringle
IPR001254 Peptidase S1, chymotrypsin
IPR001314 Peptidase S1A, chymotrypsin
IPR009003 Peptidase, trypsin-like serine and cysteine proteases
IPR003014 N/apple PAN
IPR003966 Peptidase S1A, prothrombin
IPR003609 Apple-like
IPR011358 Pept_S1A_Plasmin.

The Chi square scores for co-occurrence of domains that are present in F2 and PLG are listed below.

Domain 1Domain 2Chi Square
IPR002383 Coagulation factor, Gla region IPR001314 Peptidase S1A, chymotrypsin 115.676
IPR002383 Coagulation factor, Gla region IPR001254 Peptidase S1, chymotrypsin 113.006
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR001314 Peptidase S1A, chymotrypsin 110.211
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR001254 Peptidase S1, chymotrypsin 107.648
IPR002383 Coagulation factor, Gla region IPR009003 Peptidase, trypsin-like serine and cysteine proteases 76.5427
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR009003 Peptidase, trypsin-like serine and cysteine proteases 72.8674
IPR001314 Peptidase S1A, chymotrypsin IPR001314 Peptidase S1A, chymotrypsin 46.5897
IPR002383 Coagulation factor, Gla region IPR003966 Peptidase S1A, prothrombin 45.1782
IPR001254 Peptidase S1, chymotrypsin IPR001314 Peptidase S1A, chymotrypsin 45.1327
IPR001254 Peptidase S1, chymotrypsin IPR001254 Peptidase S1, chymotrypsin 43.707
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR003966 Peptidase S1A, prothrombin 43.1168
IPR002383 Coagulation factor, Gla region IPR000001 Kringle 40.6092
IPR000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic region IPR000001 Kringle 38.6624
IPR000001 Kringle IPR001314 Peptidase S1A, chymotrypsin 36.322
IPR000001 Kringle IPR001254 Peptidase S1, chymotrypsin 35.301
IPR001314 Peptidase S1A, chymotrypsin IPR009003 Peptidase, trypsin-like serine and cysteine proteases 33.2034
IPR001254 Peptidase S1, chymotrypsin IPR009003 Peptidase, trypsin-like serine and cysteine proteases 32.1403
IPR000001 Kringle IPR003014 N/apple PAN 31.8911
IPR000001 Kringle IPR003609 Apple-like 31.8911
IPR012051 Thrombin. IPR001314 Peptidase S1A, chymotrypsin 22.4697
IPR012051 Thrombin. IPR001254 Peptidase S1, chymotrypsin 21.9097
IPR001314 Peptidase S1A, chymotrypsin IPR003966 Peptidase S1A, prothrombin 21.3475
IPR001254 Peptidase S1, chymotrypsin IPR003966 Peptidase S1A, prothrombin 20.7503
IPR000001 Kringle IPR000001 Kringle 19.8666
IPR000001 Kringle IPR009003 Peptidase, trypsin-like serine and cysteine proteases 19.3174
IPR001314 Peptidase S1A, chymotrypsin IPR003609 Apple-like 18.9862
IPR001314 Peptidase S1A, chymotrypsin IPR003014 N/apple PAN 18.9862
IPR001254 Peptidase S1, chymotrypsin IPR003014 N/apple PAN 18.4664
IPR001254 Peptidase S1, chymotrypsin IPR003609 Apple-like 18.4664
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR003966 Peptidase S1A, prothrombin 17.7085
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR003609 Apple-like 13.9346
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR003014 N/apple PAN 13.9346
IPR012051 Thrombin. IPR009003 Peptidase, trypsin-like serine and cysteine proteases 13.6162
IPR009003 Peptidase, trypsin-like serine and cysteine proteases IPR009003 Peptidase, trypsin-like serine and cysteine proteases 13.4165

The background colour of the table refers to:

  • Blue Domain is only present in F2
  • Yellow Domain is only present in PLG
  • Green Domain is present in both F2 and PLG

 0.174
Post-translational Modifications

Protein: F2

PTMResidueReference
4-carboxyglutamate 49 HPRD
4-carboxyglutamate 50 HPRD
4-carboxyglutamate 57 HPRD
4-carboxyglutamate 59 HPRD
4-carboxyglutamate 62 HPRD
4-carboxyglutamate 63 HPRD
4-carboxyglutamate 68 HPRD
4-carboxyglutamate 69 HPRD
4-carboxyglutamate 72 HPRD
4-carboxyglutamate 75 HPRD
Carboxylation 49 PubMed, HPRD
Carboxylation 50 PubMed, HPRD
Carboxylation 57 PubMed, HPRD
Carboxylation 59 PubMed, HPRD
Carboxylation 62 PubMed, HPRD
Carboxylation 63 PubMed, HPRD
Carboxylation 68 PubMed, HPRD
Carboxylation 69 PubMed, HPRD
Carboxylation 72 PubMed, HPRD
Carboxylation 75 PubMed, HPRD
Glycosylation 121 PubMed, HPRD
Glycosylation 143 PubMed, HPRD
N-linked 121 PubMed, HPRD
N-linked 143 PubMed, HPRD
N-linked 416 PubMed, HPRD
Proteolytic Cleavage 198 PubMed, HPRD
Proteolytic Cleavage 314 PubMed, HPRD
Proteolytic Cleavage 327 PubMed, HPRD
Proteolytic Cleavage 436 PubMed, HPRD

Protein: PLG

PTMResidueReference
Disulfide Bridge 316 PubMed, HPRD
Disulfide Bridge 543 PubMed, HPRD
Disulfide Bridge 555 PubMed, HPRD
Disulfide Bridge 560 PubMed, HPRD
Disulfide Bridge 567 PubMed, HPRD
Disulfide Bridge 577 PubMed, HPRD
Glycosylation 268 PubMed, HPRD
Glycosylation 308 PubMed, HPRD
Glycosylation 365 PubMed, HPRD
N-linked 308 PubMed, HPRD
O-linked 268 PubMed, HPRD
O-linked 365 PubMed, HPRD
Phosphorylation 597 PubMed, HPRD
Phosphoserine 597 HPRD
Proteolytic Cleavage 78 PubMed, HPRD
Proteolytic Cleavage 458 PubMed, HPRD
Proteolytic Cleavage 465 PubMed, HPRD
Proteolytic Cleavage 466 PubMed, HPRD
Proteolytic Cleavage 549 PubMed, HPRD
Proteolytic Cleavage 563 PubMed, HPRD
Proteolytic Cleavage 580 PubMed, HPRD
Proteolytic Cleavage 634 PubMed, HPRD
Proteolytic Cleavage 670 PubMed, HPRD
Proteolytic Cleavage 680 PubMed, HPRD
Proteolytic Cleavage 717 PubMed, HPRD
Proteolytic Cleavage 727 PubMed, HPRD
Localisation

Protein: F2

LocalisationReference
Secreted HPRD

Protein: PLG

LocalisationReference
Secreted HPRD
Transitive Score

The common interactors between F2 and PLG that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between F2 andPLG. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , F2 has 909 interactors and PLG has 660 interactors of which there are 620 common interactors.

Common InteractorName of Common InteractorScore for F2-Interactor (?)Score for PLG-Interactor (?)
F10 F10: Coagulation factor X precursor 2.47E3 0.804
F9 F9: Coagulation factor IX precursor 386.00 386.00
SERPINB1 SERPINB1, ELANH2, MNEI, PI2: Leukocyte elastase inhibitor 370.00 0.770
SERPINB4 SERPINB4, SCCA2: Serpin B4 105.00 0.177
SERPIND1 SERPIND1, HCF2: Heparin cofactor 2 precursor 50.50 14.30
ITIH1 ITIH1, IGHEP1: Inter-alpha-trypsin inhibitor heavy chain H1 precursor 50.50 1.81
SERPING1 SERPING1, C1IN, C1NH: Plasma protease C1 inhibitor precursor 50.50 6.73
ITIH4 ITIH4, IHRP, PRO1851, ITIHL1, PK120: Inter-alpha-trypsin inhibitor heavy chain H 50.50 0.269
SERPINA4 SERPINA4, KST, PI4: Kallistatin precursor 50.50 14.30
SERPINF2 SERPINF2, AAP, PLI: Alpha-2-antiplasmin precursor 50.50 16.80
SERPINC1 SERPINC1, AT3, PRO0309: Antithrombin-III precursor 45.20 38.60
SERPINA6 SERPINA6, CBG: Corticosteroid-binding globulin precursor 16.80 43.10
SERPINA1 SERPINA1, AAT, PRO0684, PI, PRO2209: Alpha-1-antitrypsin precursor 16.80 14.30
AGT AGT, SERPINA8: Angiotensinogen precursor 16.80 14.30
SERPINA10 SERPINA10, ZPI, UNQ707/PRO1358: Protein Z-dependent protease inhibitor precursor 7.89 4.07
IGFALS IGFALS, ALS: Insulin-like growth factor-binding protein complex acid labile chai 6.17 0.385
VTN VTN: Vitronectin precursor 5.75 1.81
F12 F12: Coagulation factor XII precursor 5.75 0.852
APCS APCS, PTX2: Serum amyloid P-component precursor 5.75 0.852
HGFAC HGFAC: Hepatocyte growth factor activator precursor 5.75 0.852
AMBP AMBP, HCP, ITIL: AMBP protein precursor [Contains: Alpha-1-microglobulin 5.75 1.81
C8A C8A: Complement component C8 alpha chain precursor 5.75 1.91
HPX HPX: Hemopexin precursor 5.75 1.81
HP HP: Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta c 5.75 1.81
PROC PROC: Vitamin K-dependent protein C precursor 5.15 1.71
C6 C6: Complement component C6 precursor 5.15 0.804
APOA1 APOA1: Apolipoprotein A-I precursor 5.03 0.307
ORM2 ORM2, AGP2: Alpha-1-acid glycoprotein 2 precursor 5.03 0.307
RNASE4 ANG, RNASE5: Angiogenin precursor 5.03 0.307
HRG HRG: Histidine-rich glycoprotein precursor 5.03 0.307
APOA2 APOA2: Apolipoprotein A-II precursor 5.03 0.923
APOC4 APOC2, APC2: Apolipoprotein C-II precursor 5.03 0.923
ORM1 ORM1, AGP1: Alpha-1-acid glycoprotein 1 precursor 5.03 0.307
PON1 N/A 5.03 0.276
APOC3 APOC3: Apolipoprotein C-III precursor 5.03 0.307
AHSG AHSG, FETUA, PRO2743: Alpha-2-HS-glycoprotein precursor 5.03 0.923
PON3 PON3: Serum paraoxonase/lactonase 3 5.03 0.276
C8G C8G: Complement component C8 gamma chain precursor 5.03 0.144
HAMP HAMP, HEPC, UNQ487/PRO1003, LEAP1: Hepcidin precursor 5.03 0.144
F5 F5: Coagulation factor V precursor 4.77 0.515
SERPINA3 N/A 4.77 3.28
SERPINF1 SERPINF1, PEDF: Pigment epithelium-derived factor precursor 3.85 2.42
GGCX GGCX, GC: Vitamin K-dependent gamma-carboxylase 3.45 0.956
ASGR2 ASGR2: Asialoglycoprotein receptor 2 3.16 1.19
SERPINA7 SERPINA7, TBG: Thyroxine-binding globulin precursor 2.84 4.07
HPN HPN, TMPRSS1: Serine protease hepsin 2.83 1.07
C2 C2: Complement C2 precursor 1.91 1.81
CFB CFB, BF, BFD: Complement factor B precursor 1.91 1.81
C4BPB C4BPB: C4b-binding protein beta chain precursor 1.91 1.81
C3 1.91 0.852
APOH APOH, B2G1: Beta-2-glycoprotein 1 precursor 1.91 5.45
C4BPA C4BPA, C4BP: C4b-binding protein alpha chain precursor 1.91 0.852
CP CP: Ceruloplasmin precursor 1.76 0.251
C8B C8B: Complement component C8 beta chain precursor 1.71 1.71
ALB ALB: Uncharacterized protein ALB 1.67 0.307
ANPEP ANPEP, APN, CD13, PEPN: Aminopeptidase N 1.60 0.192
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 1.53 0.04
SERPINA5 SERPINA5, PCI, PLANH3, PROCI: Plasma serine protease inhibitor precursor 1.41 1.50
SERPINB4 SERPINB3, SCCA, SCCA1: Serpin B3 1.14 0.859
ASGR1 ASGR1: Asialoglycoprotein receptor 1 1.07 0.503
SERPINB13 SERPINB13, PI13: Serpin B13 1.02 0.770
SLC14A2 SLC14A2, HUT2, UT2: Urea transporter, kidney 1.00 0.109
F8 F8, F8C: Coagulation factor VIII precursor 1.00 0.109
SAA4 SAA4, CSAA: Serum amyloid A-4 protein precursor 0.954 0.053
APOC4 APOC4: Apolipoprotein C-IV precursor 0.954 0.025
SERPINI1 SERPINI1, PI12: Neuroserpin precursor 0.902 0.770
SERPINE1 SERPINE1, PAI1, PLANH1: Plasminogen activator inhibitor 1 precursor 0.902 370.00
HABP2 HABP2, HGFAL, PHBP: Hyaluronan-binding protein 2 precursor 0.881 0.881
HPR HPR: Haptoglobin-related protein precursor 0.881 0.293
APOM APOM, G3A, HSPC336, NG20: Apolipoprotein M 0.785 0.923
APOE APOE: Apolipoprotein E precursor 0.785 0.144
KNG1 N/A 0.785 0.923
AFM AFM, ALB2, ALBA: Afamin precursor 0.785 0.923
TTR TTR, PALB: Transthyretin precursor 0.785 0.078
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.770 0.874
TF TF, PRO1400: Serotransferrin precursor 0.704 0.129
MST1 N/A 0.704 0.276
LMAN2 LMAN2, C5orf8: Vesicular integral-membrane protein VIP36 precursor 0.594 0.057
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.575 0.062
PTGS1 PTGS1, COX1: Prostaglandin G/H synthase 1 precursor 0.575 0.0688
CDO1 CDO1: Cysteine dioxygenase type 1 0.558 0.094
CFHR2 CFHR2, CFHL2, FHR2, HFL3: Complement factor H-related protein 2 precursor 0.543 1.81
C1R C1R: Complement C1r subcomponent precursor 0.543 0.416
PROZ PROZ: Vitamin K-dependent protein Z precursor 0.543 0.543
LPA LPA: Apolipoprotein(a) precursor 0.486 0.372
PCOLCE PCOLCE, PCPE1: Procollagen C-endopeptidase enhancer 1 precursor 0.438 0.307
MBL2 MBL2, MBL: Mannose-binding protein C precursor 0.393 0.486
C9 C9: Complement component C9 precursor [Contains: Complement component C9a; Compl 0.393 0.290
FGB FGB: Fibrinogen beta chain precursor [Contains: Fibrinopeptide B] 0.393 1.62
ITIH2 N/A 0.384 0.307
TFR2 TFR2, hCG_20451: Uncharacterized protein TFR2 0.366 0.074
AGXT AGXT, AGT1, SPAT: Serine--pyruvate aminotransferase 0.351 0.117
ENPEP ENPEP: Glutamyl aminopeptidase 0.338 0.046
PCSK2 PCSK2, NEC2: Neuroendocrine convertase 2 precursor 0.338 0.037
CFH CFH, HF, HF1, HF2: Complement factor H precursor 0.324 0.307
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.318 0.041
CCL14 CCL14, NCC2, SCYA14: Small-inducible cytokine A14 precursor 0.318 0.127
CFHR4 CFHR4, CFHL4, FHR4: Complement factor H-related protein 4 precursor 0.293 0.293
CETP CETP: Cholesteryl ester transfer protein precursor 0.283 0.070
NTF3 NTF3: Neurotrophin-3 precursor 0.283 0.0425
SERPINB10 SERPINB10, PI10: Serpin B10 0.274 0.218
EDN2 EDN2: Endothelin-2 precursor 0.265 0.191
C1S C1S: Complement C1s subcomponent precursor 0.265 0.191
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.265 0.191
SHBG SHBG: Sex hormone-binding globulin precursor 0.265 0.191
A2M A2M, FWP007: Alpha-2-macroglobulin precursor 0.265 0.307
HEPH HEPH, KIAA0698, UNQ2562/PRO6242: Hephaestin precursor 0.265 0.027
SERPINH1 SERPINH1, CBP1, PIG14, CBP2, HSP47, SERPINH2: Serpin H1 precursor 0.265 0.265
SERPINA12 SERPINA12: Serpin A12 precursor 0.265 0.265
SERPINA11 SERPINA11: Serpin A11 precursor 0.265 0.265
CCL1 CCL1, SCYA1: Small-inducible cytokine A1 precursor 0.241 0.096
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.241 0.096
SERPINI2 SERPINI2, MEPI, PI14: Serpin I2 precursor 0.237 0.237
SERPINB12 SERPINB12: Serpin B12 0.237 0.237
SERPINB8 SERPINB8, PI8: Serpin B8 0.237 0.237
SLC37A4 G6PC, G6PT: Glucose-6-phosphatase 0.236 0.038
SEPP1 SEPP1, SELP: Selenoprotein P precursor 0.232 0.070
TFF2 TFF2, SML1: Trefoil factor 2 precursor 0.232 0.0425
FN1 N/A 0.209 1.53
THPO THPO, MGDF: Thrombopoietin precursor 0.209 0.083
KITLG KITLG, MGF, SCF: Kit ligand precursor 0.209 0.083
CSF3 CSF3, GCSF: Granulocyte colony-stimulating factor precursor 0.209 0.083
CCL26 CCL26, SCYA26, UNQ216/PRO242: Small-inducible cytokine A26 precursor 0.209 0.083
DCN DCN: Decorin precursor 0.209 0.083
IFNG IFNG: Interferon gamma precursor 0.209 0.083
C1QC C1QC, C1QG: Complement C1q subcomponent subunit C precursor 0.209 0.209
CCL15 CCL15, MIP5, NCC3, SCYA15: Small-inducible cytokine A15 precursor 0.209 0.083
IL4 IL4: Interleukin-4 precursor 0.209 0.083
OPTC OPTC, OPT: Opticin precursor 0.209 0.083
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.209 0.083
LOC643930 CCL3L1, D17S1718, G0S19-2, SCYA3L1: Small-inducible cytokine A3-like 1 precursor 0.209 0.083
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.209 0.083
CXCL9 CXCL9, CMK, MIG, SCYB9: Small-inducible cytokine B9 precursor 0.201 0.152
PZP PZP: Pregnancy zone protein precursor 0.201 0.191
BGN BGN: Biglycan precursor 0.192 0.077
C1QA C1QA: Complement C1q subcomponent subunit A precursor 0.192 0.192
DSPG3 EPYC, DSPG3, PGLB: Epiphycan precursor 0.192 0.062
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.187 0.075
FGA N/A 0.180 221.00
CRP CRP, PTX1: C-reactive protein precursor [Contains: C-reactive protein(1-205)] 0.176 0.026
GRN GRN: Granulins precursor 0.174 0.148
CFHR1 CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2: Complement factor H-relate 0.174 0.165
F11 F11: Coagulation factor XI precursor 0.174 0.165
C4A C4A: Complement C4-A precursor 0.174 0.165
TFPI TFPI, LACI, TFPI1: Tissue factor pathway inhibitor precursor 0.174 0.165
BGLAP BGLAP: Osteocalcin precursor 0.174 0.174
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.174 0.165
SERPINB5 0.174 0.174
CD46 N/A 0.165 0.165
ANGPTL3 ANGPTL3, ANGPT5, UNQ153/PRO179: Angiopoietin-related protein 3 precursor 0.161 0.372
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.161 0.191
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.161 0.152
CFI CFI, IF: Complement factor I precursor 0.161 0.416
F13B F13B: Coagulation factor XIII B chain precursor 0.161 0.307
CMA1 CMA1, CYH, CYM: Chymase precursor 0.161 0.152
SPOCK1 SPOCK1, SPOCK, TIC1, TICN1: Testican-1 precursor 0.156 0.148
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.156 0.148
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.156 0.148
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.156 0.148
COL18A1 N/A 0.156 0.148
CPB2 CPB2: Carboxypeptidase B2 precursor 0.156 0.148
PLAT PLAT: Tissue-type plasminogen activator precursor 0.156 0.148
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.156 0.148
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.156 75.10
LOC653509 SFTPA1, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A1 precursor 0.156 0.148
BMP1 N/A 0.156 0.148
KLK3 KLK3, APS: Prostate-specific antigen precursor 0.156 0.148
F7 F7: Coagulation factor VII precursor 0.156 0.156
SERPINB9 SERPINB9, PI9: Serpin B9 0.156 0.141
SERPINE2 SERPINE2, PI7, PN1: Glia-derived nexin precursor 0.156 74.90
SERPINB7 SERPINB7: Serpin B7 0.156 0.156
SERPINB2 SERPINB2, PAI2, PLANH2: Plasminogen activator inhibitor 2 precursor 0.156 0.156
ASPN ASPN: ASPN protein 0.156 0.077
IL2 IL2: Interleukin 2 0.156 0.062
CCL8 CCL8, MCP2, SCYA10, SCYA8: Small-inducible cytokine A8 precursor 0.156 0.062
CSF2 CSF2, GMCSF: Granulocyte-macrophage colony-stimulating factor precursor 0.156 0.055
IL5 IL5: Interleukin-5 precursor 0.156 0.062
CCL13 CCL13, MCP4, NCC1, SCYA13: Small-inducible cytokine A13 precursor 0.156 0.062
EPO EPO: Erythropoietin precursor 0.156 0.062
ECM1 ECM1: Extracellular matrix protein 1 precursor 0.152 0.028
CSF1 CSF1: Macrophage colony-stimulating factor 1 precursor 0.152 0.028
GHRL GHRL, MTLRP, UNQ524/PRO1066: Appetite-regulating hormone precursor 0.152 0.028
GRP Gastrin-releasing peptide 0.152 0.028
MMRN2 MMRN2, EMILIN3: Multimerin-2 precursor 0.152 0.028
GUCA2A GUCA2A, GUCA2: Guanylin precursor 0.152 0.028
CCL14 N/A 0.152 0.028
NULL A1BG: Alpha-1B-glycoprotein precursor 0.152 0.028
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.152 0.028
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.152 0.028
PTHLH N/A 0.152 0.028
PCSK6 N/A 0.152 0.028
CST4 CST4: Cystatin-S precursor 0.152 0.028
ACCN3 ACCN3, ASIC3, SLNAC1, TNAC1: Amiloride-sensitive cation channel 3 0.152 0.028
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.152 0.028
NOG NOG: Noggin precursor 0.152 0.028
PLAU Plasminogen activator, urokinase 0.152 0.028
LECT1 LECT1, CHMI: Chondromodulin-1 precursor 0.152 0.028
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.152 0.028
PLTP PLTP: Phospholipid transfer protein precursor 0.152 0.025
SDC1 SDC1, SDC: Syndecan-1 precursor 0.145 0.166
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.144 0.111
PLXNC1 PLXNC1, VESPR: Plexin-C1 precursor 0.143 0.143
SERPINA9 N/A 0.141 0.141
AGRP AGRP, AGRT, ART: Agouti-related protein precursor 0.140 0.026
IL22 IL22, ILTIF, UNQ3099/PRO10096: Interleukin-22 precursor 0.140 0.026
IGF2 IGF2, PP1446: Insulin-like growth factor II precursor 0.140 0.070
GAST GAST, GAS: Gastrin precursor [Contains: Gastrin-71 0.140 0.026
AFP AFP, HPAFP: Alpha-fetoprotein precursor 0.140 0.070
PRL PRL: Prolactin precursor 0.137 0.055
COL5A2 N/A 0.137 0.062
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.137 1.00
CCL5 CCL5, D17S136E, SCYA5: Small-inducible cytokine A5 precursor 0.137 0.055
COL17A1 COL17A1, BP180, BPAG2: Collagen alpha-1(XVII) chain 0.137 0.055
CSH2 GH1: Somatotropin precursor 0.137 0.055
XCL1 XCL1, LTN, SCYC1: Lymphotactin precursor 0.137 0.055
KERA KERA: Keratocan precursor 0.137 0.055
CCL21 CCL21, SCYA21, UNQ784/PRO1600: Small-inducible cytokine A21 precursor 0.137 0.055
COL1A1 COL1A1: Collagen alpha-1(I) chain precursor 0.137 0.156
IL6 IL6, IFNB2: Interleukin-6 precursor 0.137 0.055
CCL24 CCL24, MPIF2, SCYA24: Small-inducible cytokine A24 precursor 0.137 0.062
LIF LIF, HILDA: Leukemia inhibitory factor precursor 0.137 0.055
COL3A1 COL3A1: Collagen alpha-1(III) chain precursor 0.137 0.137
ADIPOQ ADIPOQ, ACDC, ACRP30, APM1, GBP28: Adiponectin precursor 0.137 0.137
CCL11 CCL11, SCYA11: Eotaxin precursor 0.137 0.055
CCL4 CCL4, CCL4L, LAG1, MIP1B, SCYA4, SCYA4L: Small-inducible cytokine A4 precursor 0.137 0.055
IL3 IL3: Interleukin-3 precursor 0.137 0.055
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.137 0.055
LUM LUM, LDC: Lumican precursor 0.137 0.055
CCL2 CCL2, MCP1, SCYA2: Small-inducible cytokine A2 precursor 0.137 0.055
OSM OSM: Oncostatin-M precursor 0.137 0.055
VNN1 VNN1: Pantetheinase precursor 0.137 0.025
CA11 CA11, CARP2, UNQ211/PRO237: Carbonic anhydrase-related protein 11 precursor 0.137 0.025
CNTN1 CNTN1: Contactin-1 precursor 0.137 0.025
LOC641705 AMY2A: Pancreatic alpha-amylase precursor 0.137 0.025
CNTN4 CNTN4: Contactin-4 precursor 0.137 0.025
ITM2C ITM2C, BRI3, hucep-14, NPD018, PSEC0047: Integral membrane protein 2C 0.137 0.025
SDC4 SDC4: Syndecan-4 precursor 0.130 0.148
CXCL12 Stromal cell-derived factor 1 delta 0.130 0.123
PRSS22 PRSS22, BSSP4, SP001LA, PRSS26, UNQ302/PRO343: Brain-specific serine protease 4 0.130 0.152
CXCL10 CXCL10, INP10, SCYB10: Small-inducible cytokine B10 precursor 0.130 0.123
EDN3 EDN3: Endothelin-3 precursor 0.130 0.109
SLPI SLPI, WAP4, WFDC4: Antileukoproteinase precursor 0.130 0.109
THBD THBD, THRM: Thrombomodulin precursor 0.130 0.109
PROS1 PROS1, PROS: Vitamin K-dependent protein S precursor 0.130 0.201
CXCL11 CXCL11, ITAC, SCYB11, SCYB9B: Small-inducible cytokine B11 precursor 0.130 0.109
NOTCH3 NOTCH3: Neurogenic locus notch homolog protein 3 precursor 0.130 0.111
CLEC3B CLEC3B, TNA: Tetranectin precursor 0.130 0.123
CSN2 CSN2, CASB: Beta-casein precursor 0.123 0.152
PF4V1 PF4V1, SCYB4V1: Platelet factor 4 variant precursor 0.123 0.123
CPN1 CPN1, ACBP: Carboxypeptidase N catalytic chain precursor 0.123 0.074
VWF VWF, F8VWF: von Willebrand factor precursor 0.123 0.049
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.123 0.0308
MMP11 MMP11, STMY3: Stromelysin-3 precursor 0.117 0.111
TIMP1 TIMP1, CLGI, TIMP: Metalloproteinase inhibitor 1 precursor 0.117 0.111
PRG4 PRG4, MSF, SZP: Proteoglycan-4 precursor 0.117 0.111
MMP8 CLG1, MMP8: Neutrophil collagenase precursor 0.117 0.111
IL2RA IL2RA: Interleukin-2 receptor alpha chain precursor 0.115 0.123
PPBP PPBP, CTAP3, SCYB7, TGB1, THBGB1: Platelet basic protein precursor 0.115 0.109
PRTN3 PRTN3, MBN: Myeloblastin precursor 0.115 0.109
PRSS1 PRSS1, TRP1, TRY1, TRYP1: Trypsin-1 precursor 0.115 0.109
PRG2 PRG2, MBP: Bone marrow proteoglycan precursor 0.115 0.109
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.115 0.115
PF4 PF4, CXCL4, SCYB4: Platelet factor 4 precursor 0.115 0.123
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.115 0.109
ELA3B ELA3B: Elastase-3B precursor 0.115 0.109
TG TG: Thyroglobulin precursor 0.115 0.109
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.115 0.109
GZMB Endogenous granzyme B 0.115 0.109
CXCL5 CXCL5, ENA78, SCYB5: Small-inducible cytokine B5 precursor 0.115 0.109
SPINT2 SPINT2, HAI2, KOP: Kunitz-type protease inhibitor 2 precursor 0.115 0.109
MMP9 MMP9, CLG4B: Matrix metalloproteinase-9 precursor 0.115 0.109
TACSTD1 TACSTD1, GA733-2, M1S2, M4S1, MIC18, TROP1: Tumor-associated calcium signal tran 0.115 0.109
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.115 0.109
CFP CFP, PFC: Properdin precursor 0.115 0.115
MUC2 MUC2, SMUC: Mucin-2 precursor 0.115 0.109
AZU1 AZU1: Azurocidin precursor 0.115 0.109
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.115 0.109
CCL22 CCL22, A-152E5.1, MDC, SCYA22: Small-inducible cytokine A22 precursor 0.115 0.109
NOTCH4 N/A 0.115 0.097
ELA2 ELA2: Leukocyte elastase precursor 0.115 0.109
REG1B REG1B, REGL: Lithostathine 1 beta precursor 0.115 0.109
CXCL1 CXCL1, GRO, GRO1, GROA, MGSA, SCYB1: Growth-regulated protein alpha precursor 0.115 0.109
SPINK1 SPINK1, PSTI: Pancreatic secretory trypsin inhibitor precursor 0.115 0.109
CSPG2 N/A 0.115 0.109
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.115 0.109
LGALS3 LGALS3, MAC2: Galectin-3 0.115 0.098
COL5A1 N/A 0.115 0.115
SFTPA2 SFTPA2, PSAP, SFTP1, SFTPA: Pulmonary surfactant-associated protein A2 precursor 0.115 0.109
EDN1 EDN1: Endothelin-1 precursor 0.115 0.109
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.115 0.123
REG1B REG1A, PSPS, REG: Lithostathine 1 alpha precursor 0.115 0.109
MMP13 MMP13: Collagenase 3 precursor 0.115 0.123
CTSG CTSG: Cathepsin G precursor 0.115 0.109
IL8 IL8: Interleukin-8 precursor 0.115 0.109
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.115 0.109
REG3A REG3A, HIP, PAP, PAP1: Regenerating islet-derived protein 3 alpha precursor 0.115 0.109
COL15A1 COL15A1: Collagen alpha-1(XV) chain precursor [Contains: Endostatin 0.115 0.109
UMOD UMOD: Uromodulin precursor 0.115 0.191
IFNA14 IFNA14: Interferon alpha-14 precursor 0.114 0.026
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.111 0.111
MGP MGP, MGLAP, GIG36: Matrix Gla protein precursor 0.109 0.109
LGALS1 LGALS1: Galectin-1 0.109 0.109
IL15RA IL15RA: Interleukin-15 receptor alpha chain precursor 0.109 0.109
CPE CPE: Carboxypeptidase E precursor 0.103 0.088
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.103 0.097
LAMA2 LAMA2: Uncharacterized protein LAMA2 0.103 0.097
KLK6 KLK6, PRSS18, PRSS9: Kallikrein-6 precursor 0.103 0.097
THBS1 THBS1, TSP, TSP1: Thrombospondin-1 precursor 0.103 0.103
CPD CPD: Carboxypeptidase D precursor 0.103 0.097
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.103 0.097
FAT2 FAT2, CDHF8, KIAA0811, MEGF1: Protocadherin Fat 2 precursor 0.103 0.097
KLK1 KLK1: Kallikrein-1 precursor 0.103 0.111
MMP1 MMP1, CLG: Interstitial collagenase precursor 0.103 0.097
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.103 0.097
SFTPD SFTPD, PSPD, SFTP4: Pulmonary surfactant-associated protein D precursor 0.103 0.097
CPA2 CPA2: Carboxypeptidase A2 precursor 0.103 0.097
MMP7 MMP7, MPSL1, PUMP1: Matrilysin precursor 0.103 0.097
CTGF CTGF, CCN2, HCS24: Connective tissue growth factor precursor 0.103 0.097
C7 C7: Complement component C7 precursor 0.103 0.103
SPON1 SPON1, KIAA0762, VSGP: Spondin-1 precursor 0.103 0.093
FGL2 FGL2: Fibroleukin precursor 0.103 0.097
TNC TNC, HXB: Tenascin precursor 0.103 0.097
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.103 0.097
MMP2 MMP2, CLG4A: 72 kDa type IV collagenase precursor 0.103 0.097
MFAP4 MFAP4: Microfibril-associated glycoprotein 4 precursor 0.103 0.097
CPM CPM: Carboxypeptidase M precursor 0.103 0.097
CPB1 CPB1, CPB, PCPB: Carboxypeptidase B precursor 0.103 0.097
COL4A1 N/A 0.103 0.097
SPARC SPARC, ON: SPARC precursor 0.103 0.097
MFAP2 MFAP2, MAGP1: Microfibrillar-associated protein 2 precursor 0.100 0.100
RNASE2 RNASE2, EDN, RNS2: Non-secretory ribonuclease precursor 0.100 0.100
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.099 0.090
COL16A1 COL16A1: Collagen alpha-1(XVI) chain precursor 0.098 0.098
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.098 0.098
ALK ALK: ALK tyrosine kinase receptor precursor 0.097 0.097
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.097 0.097
TMPRSS9 N/A 0.096 0.098
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.096 0.109
DLK1 DLK1, DLK: Delta-like protein precursor 0.096 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.096 0.109
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.096 0.109
THOP1 THOP1: Thimet oligopeptidase 0.094 0.071
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.094 0.094
SLIT2 SLIT2, SLIL3: Slit homolog 2 protein precursor 0.093 0.088
TRHR TRHR: Thyrotropin-releasing hormone receptor 0.090 0.041
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.090 0.073
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.088 0.081
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.087 0.049
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.087 0.049
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.087 0.049
TBXA2R TBXA2R: Thromboxane A2 receptor 0.087 0.049
DRD2 DRD2: D(2) dopamine receptor 0.087 0.049
C3AR1 C3AR1, AZ3B, C3R1, HNFAG09: C3a anaphylatoxin chemotactic receptor 0.087 0.049
EDA N/A 0.087 0.049
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.087 0.049
JAG2 JAG2: Jagged-2 precursor 0.086 0.098
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.086 0.098
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.086 0.098
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.086 0.098
ATRN N/A 0.086 0.098
MT1M MT1M, MT1K: Metallothionein-1M 0.083 0.083
SPP2 SPP2, SPP24: Secreted phosphoprotein 24 precursor 0.082 0.082
CYP4A22 CYP4A22, RP1-18D14.1-001: Cytochrome P450 4A22. 0.082 0.027
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.081 0.100
SELE SELE, ELAM1: E-selectin precursor 0.081 0.081
RHO RHO, OPN2: Rhodopsin 0.080 0.057
GP1BA N/A 0.080 0.0453
MEP1B MEP1B: Meprin A subunit beta precursor 0.079 0.090
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.078 0.036
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.078 0.044
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.075 0.091
ALDOB ALDOB, ALDB: Fructose-bisphosphate aldolase B 0.0739 0.0739
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.073 0.064
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.073 0.073
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.073 0.073
TACR2 TACR2, NK2R, NKNAR, TAC2R: Substance-K receptor 0.072 0.041
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.072 0.065
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.072 0.072
KEL KEL: Kell blood group glycoprotein 0.071 0.081
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.071 0.072
MARCO MARCO, SCARA2: Macrophage receptor MARCO 0.071 0.025
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.071 0.072
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.071 0.081
SORL1 SORL1: Sortilin-related receptor precursor 0.071 0.081
F2RL1 F2RL1, GPR11, PAR2: Proteinase-activated receptor 2 precursor 0.071 0.081
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.0688 0.0688
PLGLB1 PLGLB1, PLGL, PLGLB2, PLGP1, PRGB: Plasminogen-related protein B precursor 0.067 0.083
LPAL2 LPAL2, apoargC: Apolipoprotein 0.067 0.067
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.065 0.037
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.065 0.037
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.065 0.030
CCR5 CCR5: CCR5 receptor (Fragment) 0.065 0.037
EDG1 EDG1: Sphingosine 1-phosphate receptor Edg-1 0.065 0.032
APLP2 APLP2, APPL2: Amyloid-like protein 2 precursor 0.064 0.064
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.064 0.058
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.064 0.058
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.064 0.064
ITGB7 ITGB7: Integrin beta-7 precursor 0.064 0.064
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.064 0.073
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.064 35.00
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.064 0.073
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.064 0.073
F3 F3: Tissue factor precursor 0.063 0.072
F2R F2R, CF2R, PAR1, TR: Proteinase-activated receptor 1 precursor 0.063 0.072
F2RL2 F2RL2, PAR3: Proteinase-activated receptor 3 precursor 0.063 0.072
CD69 CD69: Early activation antigen CD69 0.063 0.072
SFRP1 CDNA FLJ45402 fis, clone BRHIP3029409, moderately similar to Homo sapiens secret 0.063 0.073
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.063 0.072
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.063 0.065
AREG AREG, SDGF: Amphiregulin precursor 0.063 0.072
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.063 0.072
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.063 0.072
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.063 0.072
F2RL3 F2RL3, PAR4: Proteinase-activated receptor 4 precursor 0.063 0.072
EGF EGF: Pro-epidermal growth factor precursor 0.063 0.100
ITGB4 N/A 0.063 0.072
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, testis-specific isoform precursor 0.063 0.072
MME MME, EPN: Neprilysin 0.063 0.072
AVPR1B AVPR1B, AVPR3, VPR3: Vasopressin V1b receptor 0.063 0.046
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.062 0.062
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.060 0.148
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.060 0.148
GP5 GP5: Platelet glycoprotein V precursor 0.058 0.033
CHRM2 CHRM2: Muscarinic acetylcholine receptor M2 0.058 0.033
PHGDH PHGDH, PGDH3: D-3-phosphoglycerate dehydrogenase 0.058 0.046
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.057 0.032
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.057 0.0263
GPR23 LPA4, GPR23, P2RY9: Lysophosphatidic acid receptor 4 0.057 0.032
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.057 0.032
C5AR1 C5AR1, C5AR, C5R1: C5a anaphylatoxin chemotactic receptor 0.057 0.032
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.057 0.032
GP1BB GP1BB: Platelet glycoprotein Ib beta chain precursor 0.057 0.029
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.057 0.032
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.057 0.032
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.056 0.064
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.056 0.064
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.056 0.064
LDLR LDLR: Low-density lipoprotein receptor precursor 0.056 0.064
MEP1A MEP1A: Meprin A subunit alpha precursor 0.056 0.073
CSPG4 CSPG4, MCSP: Chondroitin sulfate proteoglycan 4 precursor 0.056 0.064
SPINK2 SPINK2: Serine protease inhibitor Kazal-type 2 precursor 0.056 0.165
CRLF3 N/A 0.055 0.031
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.053 0.025
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.052 0.029
ITGAE ITGAE: Integrin alpha-E precursor 0.052 0.029
COL11A1 COL11A1, COLL6: Collagen alpha-1(XI) chain precursor 0.051 0.051
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.051 0.051
TSHR N/A 0.051 0.029
ITGA2B ITGA2B, GP2B, ITGAB: Integrin alpha-IIb precursor 0.051 0.029
ITGA3 ITGA3, MSK18: Integrin alpha-3 precursor 0.051 0.029
TLR4 TLR4: Toll-like receptor 4 precursor 0.051 0.029
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.051 0.029
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.051 0.051
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.051 0.058
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.050 0.148
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.049 0.049
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.049 0.0308
CIC CIC, KIAA0306: Protein capicua homolog 0.048 0.039
ITGAV ITGAV, MSK8, VNRA: Integrin alpha-V precursor 0.0462 0.026
LMAN1 LMAN1, ERGIC53, F5F8D: Protein ERGIC-53 precursor 0.046 0.046
P2RY4 P2RY4, NRU: P2Y purinoceptor 4 0.0453 0.0453
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.045 0.041
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.045 0.045
XRCC1 XRCC1: DNA-repair protein XRCC1 0.045 0.045
TRIM16 TRIM16, EBBP: Tripartite motif-containing protein 16 0.045 0.045
ANXA9 ANXA9, ANX31: Annexin A9 0.0446 0.0446
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.044 0.109
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.041 0.041
MASP1 MASP1, CRARF, CRARF1, PRSS5: Complement-activating component of Ra-reactive fact 0.041 0.0308
TPSG1 TPSG1, PRSS31, TMT: Tryptase gamma precursor 0.041 0.0308
IGFBP2 IGFBP2, BP2, IBP2: Insulin-like growth factor-binding protein 2 precursor 0.041 0.0308
SPINK4 SPINK4: Serine protease inhibitor Kazal-type 4 precursor 0.041 0.041
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.041 0.041
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.041 0.037
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.040 0.032
SELP SELP, GMRP, GRMP: P-selectin precursor 0.039 0.032
ARMET ARMET, ARP: Protein ARMET precursor 0.038 0.029
FNTB FNTB: Protein farnesyltransferase subunit beta 0.037 0.111
MC4R MC4R: Melanocortin receptor 4 0.037 0.0453
IL9R IL9R: Interleukin-9 receptor precursor 0.037 0.0263
HTR6 HTR6: 5-hydroxytryptamine receptor 6 0.037 0.037
CD55 CD55, CR, DAF: Complement decay-accelerating factor precursor 0.037 0.033
CANX CANX: Calnexin precursor 0.037 0.041
FGL1 FGL1, HFREP1: Fibrinogen-like protein 1 precursor 0.036 0.074
LGALS4 LGALS4: Galectin-4 0.036 0.028
ANGPTL4 ANGPTL4, ARP4, PP1158, HFARP, PSEC0166, PGAR, UNQ171/PRO197: Angiopoietin-relate 0.036 0.028
PKD1 PKD1: Polycystin-1 precursor 0.0338 0.030
OPRM1 OPRM1, MOR1: Mu-type opioid receptor 0.034 0.030
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.033 0.029
OR10H3 OR10H3: Olfactory receptor 10H3 0.033 0.041
FPR1 FPR1: fMet-Leu-Phe receptor 0.032 0.032
GP9 GP9: Platelet glycoprotein IX precursor 0.032 0.032
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.032 0.032
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.032 0.0263
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.032 0.029
SLITRK5 SLITRK5, KIAA0918, LRRC11: SLIT and NTRK-like protein 5 precursor 0.032 0.032
TPBG TPBG, 5T4: Trophoblast glycoprotein precursor 0.032 0.029
IL8RB IL8RB, CXCR2: High affinity interleukin-8 receptor B 0.032 0.032
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.032 0.032
FPRL1 FPRL1, FPR2, FPRH1, LXA4R: FMLP-related receptor I 0.032 0.032
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.031 0.025
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.0308 0.0308
PRSS8 PRSS8: Prostasin precursor 0.0308 0.0308
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.030 0.030
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.030 0.030
SOX8 SOX8: Transcription factor SOX-8 0.030 0.030
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.030 0.030
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.030 0.090
MT3 MT3: Metallothionein-3 0.029 0.029
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.029 0.029
SSTR3 SSTR3: Somatostatin receptor type 3 0.029 0.029
DRD1 DRD1: D(1A) dopamine receptor 0.029 0.029
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.029 0.029
HTR2C HTR2C, HTR1C: 5-hydroxytryptamine receptor 2C 0.029 0.029
SERPINA13 SERPINA13, UNQ6121/PRO20043: Serpin A13 precursor 0.0288 0.0288
SERPINA9 SERPINA9: Serpin peptidase inhibitor, clade A 0.0288 0.0288
SERPING1 SERPING1: Serine/cysteine proteinase inhibitor clade G member 1 splice variant 2 0.0288 0.0288
SERPINA2 SERPINA2, ARGS, ATR, PIL: Alpha-1-antitrypsin-related protein precursor 0.0288 0.0288
SERPINH1 N/A 0.0288 0.0288
SERPINB6 N/A 0.0288 0.0288
SERPINB12 SERPINB12: SERPINB12 protein 0.0288 0.0288
SERPINB11 SERPINB11: Serpin B11 0.0288 0.0288
PCGF6 N/A 0.028 0.028
LNX1 N/A 0.028 0.028
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.028 0.028
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.028 0.028
CGN N/A 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.028
C1QTNF4 C1QTNF4, CTRP4: Complement C1q tumor necrosis factor-related protein 4 precursor 0.028 0.028
IRF2BP2 IRF2BP2, RP4-781K5.1-002: Interferon regulatory factor 2-binding protein 2. 0.028 0.028
TUBGCP6 TUBGCP6, GCP6, KIAA1669: Gamma-tubulin complex component 6 0.028 0.028
LAMB2 LAMB2, LAMS: Laminin subunit beta-2 precursor 0.028 0.028
CPA4 CPA4, CPA3, UNQ694/PRO1339: Carboxypeptidase A4 precursor 0.028 0.028
ANGPT4 ANGPT4, ANG3, ANG4: Angiopoietin-4 precursor 0.028 0.036
TM4SF5 TM4SF5: Transmembrane 4 L6 family member 5 0.027 0.027
FN1 FN1, FN: Fibronectin precursor 0.027 0.051
MST1 MST1, D3F15S2, DNF15S2, HGFL: Hepatocyte growth factor-like protein precursor 0.027 0.051
C5 C5: Complement C5 precursor [Contains: Complement C5 beta chain; Complement C5 a 0.027 0.051
ITGB1 ITGB1, FNRB, MDF2, MSK12: Integrin beta-1 precursor 0.027 0.051
PLAU PLAU: Urokinase-type plasminogen activator precursor 0.027 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.027 0.027
KLKB1 N/A 0.027 0.051
CD74 CD74, DHLAG: HLA class II histocompatibility antigen gamma chain 0.027 0.051
MMRN1 MMRN1, ECM, EMILIN4, MMRN: Multimerin-1 precursor 0.027 0.051
COL4A2 COL4A2: Collagen alpha-2(IV) chain precursor [Contains: Canstatin] 0.027 0.051
SDC3 SDC3, KIAA0468: Syndecan-3 0.027 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.027 0.051
SEMG1 SEMG1, SEMG: Semenogelin-1 precursor 0.027 0.051
C4B C4B: Complement C4-B precursor 0.027 0.051
CSPG5 N/A 0.027 0.051
LTBP1 LTBP1: Latent-transforming growth factor beta-binding protein, isoform 1S precur 0.027 0.051
SPOCK3 SPOCK3, TICN3, UNQ409/PRO771: Testican-3 precursor 0.027 0.051
SPARCL1 SPARCL1: SPARC-like protein 1 precursor 0.027 0.051
ELTD1 ELTD1, RP11-143H12.1-002: EGF, latrophilin and seven transmembrane domain contai 0.027 0.051
SDC2 SDC2, HSPG1: Syndecan-2 precursor 0.027 0.051
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.027 0.027
IFRD2 0.027 0.027
LAMC2 LAMC2, LAMB2T, LAMNB2: Laminin subunit gamma-2 precursor 0.027 0.027
WISP3 LIBC, WISP3, RP1-142L7.3-004, hCG_34804: Lost in inflammatory breast cancer tumo 0.027 0.027
ITLN2 ITLN2, UNQ2789/PRO7179: Intelectin-2 precursor 0.027 0.027
CPO CPO: Carboxypeptidase O precursor 0.027 0.027
SCARF2 SCARF2, SREC2, SREPCR: Scavenger receptor class F member 2 precursor 0.027 0.027
PRRG2 PRRG2, PRGP2, TMG2: Transmembrane gamma-carboxyglutamic acid protein 2 precursor 0.027 0.027
WFDC6 WFDC6, C20orf171, WAP6: WAP four-disulfide core domain protein 6 precursor 0.027 0.027
THSD3 N/A 0.027 0.027
MPEG1 MPEG1: Macrophage-expressed gene 1 protein precursor 0.027 0.027
WFDC12 WFDC12, C20orf122, UNQ544/PRO844, WAP2: WAP four-disulfide core domain protein 1 0.027 0.027
CXCL16 CXCL16, SCYB16, UNQ2759/PRO6714, SRPSOX: Small-inducible cytokine B16 precursor 0.027 0.027
CFC1 CFC1: Cryptic protein precursor 0.027 0.027
UNQ739 VWC2, UNQ739, hCG_2045125, tcag7.1302: von Willebrand factor C domain-containing 0.027 0.027
WFDC3 WFDC3, WAP14: WAP four-disulfide core domain protein 3 precursor 0.027 0.027
NETO1 N/A 0.027 0.027
ADAMTS10 ADAMTS10: ADAMTS-10 precursor 0.027 0.027
REG4 REG4, GISP, RELP: Regenerating islet-derived protein 4 precursor 0.027 0.027
NTN4 NTN4: Netrin-4 precursor 0.027 0.027
COL11A2 COL11A2: Collagen alpha-2(XI) chain precursor 0.027 0.027
TPSAB1 N/A 0.027 0.027
CILP2 CILP2: Cartilage intermediate layer protein 2 precursor 0.027 0.027
FSTL5 FSTL5, KIAA1263: Follistatin-related protein 5 precursor 0.027 0.027
ADAMTS17 ADAMTS17: ADAMTS-17 precursor 0.027 0.027
NELL2 NELL2, NRP2: Protein kinase C-binding protein NELL2 precursor 0.027 0.027
ELA2A ELA2A: Elastase-2A precursor 0.027 0.027
PRSS36 PRSS36: Polyserase-2 precursor 0.027 0.027
ADAMTSL1 N/A 0.027 0.027
ADAMTS19 ADAMTS19: ADAMTS-19 precursor 0.027 0.027
CR1L complement component (3b/4b) receptor 1-like 0.027 0.027
HHIP HHIP, HIP, UNQ5825/PRO19644: Hedgehog-interacting protein precursor 0.027 0.027
CFHR3 CFHR3, CFHL3, FHR3: Complement factor H-related protein 3 precursor 0.027 0.027
PRSS21 PRSS21, ESP1, UNQ266/PRO303, TEST1: Testisin precursor 0.027 0.027
ADAMTS18 ADAMTS18, ADAMTS21: ADAMTS-18 precursor 0.027 0.027
CLEC3A CLEC3A: C-type lectin domain family 3, member A 0.027 0.027
MASP2 MASP2: Mannan-binding lectin serine protease 2 precursor 0.027 0.027
CSPG3 CSPG3, NCAN, NEUR: Neurocan core protein precursor 0.027 0.027
PRRG4 PRRG4, TMG4: Transmembrane gamma-carboxyglutamic acid protein 4 precursor 0.027 0.027
KLK9 KLK9: Kallikrein-9 precursor 0.027 0.027
WFDC2 WFDC2, HE4, WAP5: WAP four-disulfide core domain protein 2 precursor 0.027 0.027
CLEC14A CLEC14A, C14orf27, UNQ236/PRO269, EGFR5: C-type lectin domain family 14 member A 0.027 0.027
KREMEN2 KREMEN2, KRM2: Kremen protein 2 precursor 0.027 0.027
C21orf29 TSPEAR, C21orf29: Protein TSPEAR precursor 0.027 0.027
NTNG2 N/A 0.027 0.027
PAPPA2 PAPPA2, PLAC3: Pappalysin-2 precursor 0.027 0.027
WFDC10A WFDC10A, C20orf146, WAP10: WAP four-disulfide core domain protein 10A precursor 0.027 0.027
SPINK7 SPINK7, ECG2, UNQ745/PRO1474: Serine protease inhibitor Kazal-type 7 precursor 0.027 0.027
KLK12 KLK12, KLKL5, UNQ669/PRO1303: Kallikrein-12 precursor 0.027 0.027
PLGLA1 PLGLA1, PLGP2: Plasminogen-related protein A precursor 0.027 0.027
CSN1S1 CSN1S1, CASA, CSN1: Alpha-S1-casein precursor [Contains: Casoxin-D] 0.027 0.027
ND4L MT-ND4L, MTND4L, NADH4L, ND4L: NADH-ubiquinone oxidoreductase chain 4L 0.027 0.027
REG3G REG3G, PAP1B, UNQ429/PRO162: Regenerating islet-derived protein 3 gamma precurso 0.027 0.027
ITLN1 ITLN1, INTL, UNQ640/PRO1270, ITLN, LFR: Intelectin-1 precursor 0.027 0.027
PRRG1 PRRG1, PRGP1, TMG1: Transmembrane gamma-carboxyglutamic acid protein 1 precursor 0.027 0.027
PRSS27 PRSS27, MPN, UNQ1884/PRO4327: Serine protease 27 precursor 0.027 0.027
MUC13 MUC13, DRCC1, UNQ6194/PRO20221, RECC: Mucin-13 precursor 0.027 0.027
WISP3 WISP3, CCN6, UNQ462/PRO790/PRO956: WNT1-inducible-signaling pathway protein 3 pr 0.027 0.027
GP2 GP2: Pancreatic secretory granule membrane major glycoprotein GP2 precursor 0.027 0.027
KNG1 KNG1, BDK, KNG: Kininogen-1 precursor 0.026 0.026
NUPL1 NUPL1, KIAA0410: Nucleoporin p58/p45 0.0258 0.0258
MT1F MT1F, PRO0376: Metallothionein-1F 0.025 0.054
UNC5D N/A 0.025 0.025
SCRIB N/A 0.025 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.025
0.572
Total Score 1.89E5