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Evidence of Interaction Between MAPK1 and CBL

The interaction score between MAPK1 and CBL is 8.86.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and CBL = -0.05

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology
OrganismMAPK1 OrthologueCBL OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
worm P39745 1 Q19019 0.232
fly P40417 1 Q9VSK2 0.118

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in MAPK1 and CBL:
Domains in MAPK1Domains in CBL
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR001841 Zn-finger, RING
IPR000449 Ubiquitin-associated domain
IPR000980 SH2 motif
IPR000217 Tubulin
IPR003153 Adaptor protein Cbl, N-terminal
IPR011992 EF-Hand_type.
IPR013090 Phospholip_A2_AS.

The Chi square scores for co-occurrence of domains that are present in MAPK1 and CBL are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR008271 Serine/threonine protein kinase, active site IPR000980 SH2 motif 41.4368
IPR008271 Serine/threonine protein kinase, active site IPR011992 EF-Hand_type. 18.67
IPR002290 Serine/threonine protein kinase IPR000980 SH2 motif 18.5445
IPR011009 Protein kinase-like IPR001841 Zn-finger, RING 15.6712
IPR000719 Protein kinase IPR011992 EF-Hand_type. 15.5567
IPR000719 Protein kinase IPR001841 Zn-finger, RING 14.0542
IPR002290 Serine/threonine protein kinase IPR011992 EF-Hand_type. 9.84625
IPR011009 Protein kinase-like IPR011992 EF-Hand_type. 9.34155
IPR003527 MAP kinase IPR000980 SH2 motif 3.65309
IPR000719 Protein kinase IPR003153 Adaptor protein Cbl, N-terminal 3.06419
IPR011009 Protein kinase-like IPR003153 Adaptor protein Cbl, N-terminal 3.04324
IPR002290 Serine/threonine protein kinase IPR001841 Zn-finger, RING 2.86027
IPR008271 Serine/threonine protein kinase, active site IPR001841 Zn-finger, RING 2.52183
IPR008349 ERK1/2 MAP kinase IPR000980 SH2 motif 0.969135
IPR011009 Protein kinase-like IPR000217 Tubulin 0.524874
IPR011009 Protein kinase-like IPR000449 Ubiquitin-associated domain 0.41941
IPR008271 Serine/threonine protein kinase, active site IPR000449 Ubiquitin-associated domain 0.0564771
IPR002290 Serine/threonine protein kinase IPR000449 Ubiquitin-associated domain 0.0551714
IPR008271 Serine/threonine protein kinase, active site IPR000217 Tubulin 0.0424984
IPR000719 Protein kinase IPR000217 Tubulin 0.0254403
IPR002290 Serine/threonine protein kinase IPR000217 Tubulin 0.00321315
IPR000719 Protein kinase IPR000449 Ubiquitin-associated domain 0.00138935

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in CBL
  • Green Domain is present in both MAPK1 and CBL

 0.165
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: CBL

PTMResidueReference
Phosphorylation 371 PubMed, HPRD
Phosphorylation 619 PubMed, HPRD
Phosphorylation 623 PubMed, HPRD
Phosphorylation 639 PubMed, HPRD
Phosphorylation 642 PubMed, HPRD
Phosphorylation 667 PubMed, HPRD
Phosphorylation 669 PubMed, HPRD
Phosphorylation 674 PubMed, HPRD
Phosphorylation 675 PubMed, HPRD
Phosphorylation 700 PubMed, HPRD
Phosphorylation 731 PubMed, HPRD
Phosphorylation 774 PubMed, HPRD
Phosphoserine 669 HPRD
Phosphotyrosine 371 PubMed, HPRD
Phosphotyrosine 674 HPRD
Phosphotyrosine 700 HPRD
Phosphotyrosine 774 HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: CBL

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between MAPK1 and CBL that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andCBL. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and CBL has 1376 interactors of which there are 922 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for CBL-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 0.097
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.111
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 94.70 0.111
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.148
DUSP10 DUSP10, MKP5: Dual specificity protein phosphatase 10 12.60 0.027
CDK2 CDK2: Cell division protein kinase 2 6.80 0.111
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.049
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 3.35 0.027
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.111
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 2.02 0.090
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.975 0.123
PLEK PLEK, P47: Pleckstrin 0.515 0.152
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.073
MSN MSN: Moesin 0.461 0.064
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.655
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.073
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.097
CRKL CRKL: Crk-like protein 0.461 0.064
JAK1 0.461 0.577
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.111
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.111
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.109
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.081
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.073
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.097
STK10 STK10: Uncharacterized protein STK10 0.385 0.111
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 277.00
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.655
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.073
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.372 0.064
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.372 0.097
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.073
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.655
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.090
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.064
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.033
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.073
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.655
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 0.655
JUND JUND: Transcription factor jun-D 0.372 0.0308
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.140
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.307 0.072
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.072
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.123
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.152
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.307 0.072
ETS1 ETS1, EWSR2: Protein C-ets-1 0.275 0.056
SYK SYK: Tyrosine-protein kinase SYK 0.275 0.808
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 0.064
DOK1 DOK1: Docking protein 1 0.275 0.111
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.655
JUNB JUNB: Transcription factor jun-B 0.275 0.035
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.097
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.275 0.577
HCK N/A 0.275 0.655
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.111
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.136
DUSP23 DUSP23, LDP3, VHZ: Dual specificity protein phosphatase 23 0.265 0.027
STYX STYX: Serine/threonine/tyrosine-interacting protein 0.265 0.027
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.081
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.260 0.029
BACH1 BACH1: Transcription regulator protein BACH1 0.251 0.062
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.251 0.081
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.109
GAB2 N/A 0.251 0.109
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.731
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.111
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.073
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.233 0.035
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.233 0.136
WASPIP N/A 0.233 0.073
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.111
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.090
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.041
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.111
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.111
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.097
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.136
RASA3 RASA3: Ras GTPase-activating protein 3 0.225 0.073
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.136
CCNH CCNH: Cyclin-H 0.225 0.035
JUN JUN: Transcription factor AP-1 0.225 0.035
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.064
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.111
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.111
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.073
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.064
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.123
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.210 0.039
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.123
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.109
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.081
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.140
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.152
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.123
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.100
RPS6KB1 N/A 0.188 0.097
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.111
FNBP1 N/A 0.188 0.111
GMIP GMIP: GEM-interacting protein 0.188 0.033
CXorf9 N/A 0.188 0.111
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.111
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.0308
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.111
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.097
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.097
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.111
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.136
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.152
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.171 0.088
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.097
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.058
NCK2 NCK2: Cytoplasmic protein NCK2 0.171 30.80
PSD TYL: TYL protein 0.171 0.058
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.090
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.171 0.073
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.090
MAP2K5 N/A 0.165 0.109
NF2 NF2, SCH: Merlin 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.109
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.109
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.109
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.109
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.109
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.980
PSCD2 N/A 0.165 0.109
NSBP1 NSBP1: Nucleosome-binding protein 1 0.165 0.028
BID BID: BH3-interacting domain death agonist 0.165 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.980
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.109
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.049
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.165 0.028
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.109
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.109
ARFGAP1 N/A 0.155 0.048
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.152
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.155 0.081
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.153 0.045
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 1.13
ETS2 ETS2: Protein C-ets-2 0.152 0.109
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.152 0.081
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.109
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.644
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.098
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
ELMO1 N/A 0.148 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.098
ARHGEF7 N/A 0.148 0.098
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.098
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.044
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.148 0.025
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.148
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.878
CREB1 CREB1: cAMP response element-binding protein 0.148 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.025
CCNT2 CCNT2: Cyclin-T2 0.148 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.025
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.098
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.148 0.047
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 8.34
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.878
STAT3 0.148 0.098
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.098
DUSP13 DUSP13, TMDP: Dual specificity protein phosphatase 13 0.141 0.028
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.139 0.035
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.029
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.111
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.111
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.111
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.111
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.097
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.111
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.139 0.069
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.111
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.136
ATM ATM: Serine-protein kinase ATM 0.139 0.111
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.097
CD2AP CD2AP: CD2-associated protein 0.139 0.090
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.073
FYN N/A 0.137 0.143
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.156
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.137
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.136 0.097
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.136 0.064
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.136 0.064
RDX RDX: Radixin 0.136 0.064
VIL2 N/A 0.136 0.064
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.136 0.058
CCNB1 Cyclin B1 0.136 0.035
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.064
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.033
CENTA1 CENTA1: Centaurin-alpha 1 0.128 0.041
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.123
RB1 RB1: Retinoblastoma-associated protein 0.127 0.034
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.123
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.152
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.191
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.123
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.077
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.051
TNFRSF1B TNFRSF1B, TNFBR, TNFR2: Tumor necrosis factor receptor superfamily member 1B pre 0.124 0.045
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.081
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.062
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.072
ERG ERG: Transcriptional regulator ERG 0.123 0.062
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.081
PPP1R8 N/A 0.118 0.0308
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.111
THOC1 THOC1, HPR1: THO complex subunit 1 0.114 0.073
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.111
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.097
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.114 0.058
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.114 0.049
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.088
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.114 0.073
CDK5 CDK5: Cell division protein kinase 5 0.114 0.097
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.111
RPS10 RPS10: 40S ribosomal protein S10 0.114 0.064
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.111
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.111
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.113 0.028
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.111 0.041
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.111 0.577
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.111 0.073
PLD2 PLD2: Phospholipase D2 0.111 0.064
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.111 0.073
APS SH2B2, APS: SH2B adapter protein 2 0.111 0.073
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.111 0.577
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.111 0.097
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.110 0.902
BMX N/A 0.110 0.644
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.0688
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.0688
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.109
MCF2 MCF2, DBL: Proto-oncogene DBL 0.109 0.081
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.109 0.0263
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.109 0.098
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.109 0.123
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.099 0.090
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.098 0.731
IRS1 IRS1: Insulin receptor substrate 1 0.098 0.152
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.062
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.062
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 0.062
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.098 0.0688
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.098 0.0688
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.097 0.097
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.097
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.064
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.097 1.01
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.088
PLD1 PLD1: Phospholipase D1 0.097 0.073
DAB1 DAB1: Disabled homolog 1 0.097 0.097
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.062
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.098
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.109
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.152
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.096 0.031
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.152
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.072
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.123
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.081
NFATC1 N/A 0.096 0.062
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.096 0.026
CIITA CIITA, MHC2TA: MHC class II transactivator 0.096 0.037
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.091 0.045
PTPRZ1 N/A 0.090 0.037
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.088 0.577
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.088 0.035
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.088 0.064
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.055
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.097
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.086 0.0308
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 0.097
TP53 TP53, P53: Cellular tumor antigen p53 0.086 0.056
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.111
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.111
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.097
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.111
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.136
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.064
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.088
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.086 0.043
RELA RELA, NFKB3: Transcription factor p65 0.086 0.056
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.064
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.064
CDK5R1 CDK5R1, CDK5R, NCK5A: Cyclin-dependent kinase 5 activator 1 precursor 0.086 0.044
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.109
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.109
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.165
HES6 HES6: Transcription cofactor HES-6 0.083 0.083
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.165
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.109
MAPKAPK5 N/A 0.083 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.109
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.165
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.04
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.109
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.165
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.083
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.109
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.083 0.028
MAPK15 N/A 0.083 0.165
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.083
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.109
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.083 0.143
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.0818 0.028
IRF3 IRF3: Interferon regulatory factor 3 0.080 0.062
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.078 0.073
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 4.41
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.078 0.056
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 2.47
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.078 0.073
LCP1 LCP1, PLS2: Plastin-2 0.078 0.073
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.078 0.073
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.078 0.056
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.0453
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.072
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.191
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.152
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.191
PRKAA1 N/A 0.077 0.251
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.081
STK16 N/A 0.077 0.152
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.077 0.100
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.075 0.051
FADD FADD, MORT1: Protein FADD 0.075 0.045
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.075 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.148
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.025
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.098
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.098
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.098
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.148
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.047
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.878
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.148
TFAP4 TFAP4: Transcription factor AP-4 0.075 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.165
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.044
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.148
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.148
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.075 0.047
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.148
MAX MAX: Protein max 0.075 0.025
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.075 0.025
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.148
GIT2 N/A 0.075 0.047
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.098
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.148
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.044
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.075 0.025
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.098
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.148
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.148
CNN2 CNN2: Calponin-2 0.075 0.109
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.148
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.075 0.025
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.073 0.046
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.073 0.041
GABRR1 N/A 0.0727 0.051
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.051
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.097
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.071 0.043
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.071 0.097
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.071 0.033
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.109
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.026
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.037
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.062
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.070 0.062
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.055
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.070 0.026
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.069 0.111
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.136
CDK4 CDK4: Cell division protein kinase 4 0.069 0.111
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.097
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.097
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.073
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.111
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.069 0.111
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.097
CDK6 CDK6: Cell division protein kinase 6 0.069 0.111
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.171
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.111
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.136
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.043
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.171
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.067 0.318
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.041
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.063 0.029
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.029
EXOC2 N/A 0.063 0.027
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.063 0.056
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.063 0.056
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.063 0.056
YY1 YY1: Transcriptional repressor protein YY1 0.063 0.056
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.029
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.063 0.073
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.063 0.056
GSK3B N/A 0.063 0.029
ACTG1 ACTB: Actin, cytoplasmic 1 0.063 0.029
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.033
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.063 0.027
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.063 0.029
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.033
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.063 0.029
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.063 0.033
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.063 0.064
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.063 0.073
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.073
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.063 0.056
CUL5 CUL5, VACM1: Cullin-5 0.063 0.111
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.152
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.152
GRLF1 N/A 0.062 0.127
MDM4 MDM4, MDMX: Mdm4 protein 0.062 0.062
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.062 0.065
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.109
COBL N/A 0.062 0.065
SPTAN1 N/A 0.062 0.072
VIM VIM: Vimentin 0.060 0.055
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.041
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.058 0.041
GLRA1 N/A 0.058 0.057
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.057 0.051
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.057 0.051
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.057 0.039
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.056 0.046
STAM2 STAM2: Signal transducing adapter molecule 2 0.056 0.148
WEE1 WEE1: Wee1-like protein kinase 0.056 0.136
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.056 0.090
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.088
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.136
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.056 0.577
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.136
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.090
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.097
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.136
NOS1 NOS1: Nitric-oxide synthase, brain 0.056 0.033
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.055 0.0338
TP73 TP73, P73: Tumor protein p73 0.055 0.109
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.109
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.111
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.054 0.027
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.053 0.034
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.028
RAB4A N/A 0.052 0.028
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.052 0.028
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.052 0.055
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.072
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.055
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.062
FUBP1 N/A 0.052 0.037
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.052 0.037
MVP MVP, LRP: Major vault protein 0.052 0.030
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.032
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.052 0.062
LIMS1 N/A 0.052 0.032
RBM14 RBM14, SIP: RNA-binding protein 14 0.052 0.026
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.052 0.077
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.037
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.026
RAPH1 N/A 0.051 0.051
PTPRA N/A 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
C9orf88 N/A 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
GRB10 N/A 0.051 0.051
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.051 0.041
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.050
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.111
HES1 HES1, HL, HRY: Transcription factor HES-1 0.050 0.056
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.050 0.058
NFIB N/A 0.049 0.034
CDKL5 N/A 0.049 0.109
DAPK2 DAPK2: Death-associated protein kinase 2 0.049 0.123
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.049 0.0688
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.049 0.0688
LAT LAT: Linker for activation of T-cells family member 1 0.049 0.0688
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.049 0.0688
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.0688
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.0688
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.034
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.049 0.034
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.049 0.0688
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.049 0.0688
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.049 0.0688
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.049 0.034
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.049 0.0688
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.049 0.540
SORBS3 SORBS3, SCAM1: Vinexin 0.049 43.20
DYRK3 N/A 0.049 0.225
MYF5 MYF5: Myogenic factor 5 0.049 0.056
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.111
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.057
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.048 0.109
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.048 0.062
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.048 0.037
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.048 0.029
MKI67 MKI67: Antigen KI-67 0.048 0.039
LMNA LMNA, LMN1: Lamin-A/C 0.047 0.025
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.047 0.148
SOX8 SOX8: Transcription factor SOX-8 0.047 0.025
LPXN LPXN, LDLP: Leupaxin 0.046 0.041
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.046 0.056
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.046 0.056
CBX3 CBX3: Chromobox protein homolog 3 0.046 0.056
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.136
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.046 0.049
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.029
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.041
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.033
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.046 0.056
SP3 SP3: Transcription factor Sp3 0.046 0.049
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.046 0.033
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.046 0.027
TBCE TBCE: Tubulin-specific chaperone E 0.046 0.033
BRPF1 BRPF1, BR140: Peregrin 0.046 0.069
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.046 0.027
MTF1 MTF1: Metal regulatory transcription factor 1 0.046 0.069
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.046 0.029
FLII FLII, FLIL: Protein flightless-1 homolog 0.046 0.051
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.046 0.033
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.046 0.033
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.111
CCR5 CCR5: CCR5 receptor (Fragment) 0.046 0.063
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.046 0.037
TNFRSF10C TNFRSF10C, DCR1, UNQ321/PRO366, LIT, TRAILR3, TRID: Tumor necrosis factor recept 0.0453 0.051
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.0453 0.025
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.0453 0.051
EPOR EPOR: Erythropoietin receptor precursor 0.0453 0.051
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.0453 0.051
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.097
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 0.111
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.044 0.069
MYO3A MYO3A: Myosin IIIA 0.044 0.097
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.097
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.064
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.044 0.088
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.111
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.044 0.090
CTTN CTTN, EMS1: Src substrate cortactin 0.044 0.065
CNN3 CNN3: Calponin-3 0.044 0.065
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.136
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.044 0.039
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.062
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.062
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.044 0.062
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.044 0.030
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.030
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.030
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.043 0.088
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.0425 0.0263
TCOF1 N/A 0.0425 0.026
NUP214 N/A 0.0425 0.026
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.0425 0.026
SH3BP3 0.0425 0.055
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.0425 0.026
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0425 0.037
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.0425 0.062
XRCC1 XRCC1: DNA-repair protein XRCC1 0.0425 0.049
ZNF267 ZNF267: Zinc finger protein 267 0.0425 0.062
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.042 0.053
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.041
GLRB GLRB: Glycine receptor subunit beta precursor 0.041 0.037
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.041 0.445
KIT KIT: Mast/stem cell growth factor receptor precursor 0.041 0.318
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.040 0.046
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.111
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.097
GFAP GFAP: Glial fibrillary acidic protein 0.039 0.029
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.039 0.029
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.038 0.069
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.038 0.029
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.033
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.033
TLN1 TLN1: Uncharacterized protein TLN1 0.038 0.064
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.038 0.027
KCTD12 KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12 0.038 0.035
MYH9 MYH9: Myosin-9 0.038 0.111
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.038 0.069
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.090
PHF10 N/A 0.038 0.056
RANBP9 RANBP9, RANBPM: Ran-binding protein 9 0.038 0.086
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.038 0.029
ZNF335 ZNF335: Zinc finger protein 335 0.038 0.056
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.038 0.035
CREBBP CREBBP, CBP: CREB-binding protein 0.038 0.049
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.038 0.029
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.051
RNF11 RNF11, CGI-123: RING finger protein 11 0.038 0.044
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.029
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.038 0.056
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.056
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.037 0.045
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.037 0.063
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.037 0.051
RAP1GA1 N/A 0.037 0.025
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.037 0.051
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.037 0.051
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.037 0.045
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.037 0.051
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.037 0.025
GHR GHR: Growth hormone receptor precursor 0.037 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.036 0.051
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.036 0.025
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.036 0.051
CRLF3 N/A 0.036 0.045
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.051
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.036 0.045
CD7 CD7: T-cell antigen CD7 precursor 0.036 0.045
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.036 0.051
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.036 0.045
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.036 0.051
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.035 0.073
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.034 0.042
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.0688
MAL2 MAL2: Protein MAL2 0.034 0.034
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.041
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.033 0.025
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.033 0.045
PRLR PRLR: Prolactin receptor precursor 0.033 0.063
ITGB4 N/A 0.032 0.051
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.032 0.045
F3 F3: Tissue factor precursor 0.032 0.051
IL9R IL9R: Interleukin-9 receptor precursor 0.032 0.051
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.032 0.029
ZFX ZFX: Zinc finger X-chromosomal protein 0.032 0.077
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.032 0.152
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.032 0.026
COIL COIL, CLN80: Coilin 0.032 0.032
HIVEP1 N/A 0.032 0.062
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.032
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.032
ZYX ZYX: Zyxin 0.032 0.032
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.032 0.032
RBM6 RBM6, DEF3: RNA-binding protein 6 0.032 0.026
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.032 0.123
UBAP2 N/A 0.032 0.026
SORL1 SORL1: Sortilin-related receptor precursor 0.032 0.051
CUL2 CUL2: Cullin-2 0.032 0.037
RYR2 RYR2: Ryanodine receptor 2 0.031 0.045
DES DES: Desmin 0.031 0.032
KRT18 KRT18: Uncharacterized protein KRT18 0.031 0.034
NEO1 NEO1, NGN: Neogenin precursor 0.029 0.057
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.029 0.286
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.029 0.041
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.029 0.051
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.029 0.025
EGF EGF: Pro-epidermal growth factor precursor 0.029 0.051
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.029 0.025
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.029 0.051
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.037
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.029 173.00
AIP AIP, XAP2: AH receptor-interacting protein 0.029 0.056
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.029 0.097
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.029 0.056
POLB POLB: DNA polymerase beta 0.029 0.029
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.029
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.029 0.064
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.029 0.056
POLR2A POLR2A: Uncharacterized protein POLR2A 0.029 0.029
SP1 SP1, TSFP1: Transcription factor Sp1 0.029 0.049
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.029 0.056
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.069
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.029 0.033
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.029 0.056
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.029 0.051
PPP2CB PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0.029 0.026
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.056
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.029 0.069
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.029 0.029
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.029 0.069
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
KIF1B N/A 0.028 0.028
CASP14 CASP14: Caspase-14 precursor 0.028 0.049
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.083
CORO6 N/A 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.083
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.028 0.083
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.049
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.109
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.028 0.083
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
WDR54 N/A 0.028 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.049
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
IRF7 N/A 0.028 0.028
C13orf8 N/A 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.049
C20orf18 N/A 0.028 0.165
DSP DSP: Desmoplakin 0.028 0.083
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.028 0.028
ZNF579 ZNF579: Zinc finger protein 579 0.028 0.083
CABLES1 N/A 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.083
SNRPB N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.052
ZNF265 N/A 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.049
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.028 0.083
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
CUTL1 CUTL1: Homeobox protein cut-like 1 0.028 0.028
HDAC8 N/A 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.052
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.028 0.083
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.165
PHLDB2 N/A 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.049
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.049
DUSP15 N/A 0.028 0.028
AXIN1 0.028 0.049
UHRF1 0.028 0.083
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.028
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.028 0.083
PPEF1 N/A 0.028 0.165
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.049
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.028 0.037
PRPH PRPH, NEF4, PRPH1: Peripherin 0.0277 0.0453
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
FAM43A N/A 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
OSBPL9 N/A 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.217
PARP9 N/A 0.027 0.027
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
ASB3 ASB3: ASB3 protein 0.027 0.027
LILRB1 N/A 0.027 0.063
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.027 0.051
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.027 0.045
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.026 0.046
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.026 0.445
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.026 0.318
RGS4 RGS4: Regulator of G-protein signaling 4 0.026 0.032
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.030
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.026 0.081
KIF23 N/A 0.026 0.026
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.026
ESPL1 N/A 0.026 0.026
MT3 MT3: Metallothionein-3 0.026 0.026
TRRAP N/A 0.026 0.026
PPARGC1A PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1: Peroxisome proliferator-activated receptor 0.026 0.026
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.026 0.062
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.026 0.030
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.026 0.026
PHB2 PHB2, BAP, REA: Prohibitin-2 0.026 0.030
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 1.20
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.026 0.062
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.0263
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.0253 0.038
F5 F5: Coagulation factor V precursor 0.025 0.031
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.025 0.045
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.075
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
NIPBL N/A 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.025
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.025
ATXN2L N/A 0.025 0.025
DLX3 DLX3: Homeobox protein DLX-3 0.025 0.025
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.036
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
FLJ23436 N/A 0.025 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.075
DIDO1 N/A 0.025 0.075
CAMKK1 N/A 0.025 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.075
CAMK2A N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.044
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.098
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
NES N/A 0.025 0.028
KCTD1 0.025 0.025
HDAC7A N/A 0.025 0.025
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.075
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.075
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.044
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.025 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.036
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.025 0.075
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.025
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.025 0.075
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
LMO6 LMO6: LIM domain only protein 6 0.025 0.044
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.036
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.044
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.075
MYO18A 0.025 0.098
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.025 0.075
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.044
TCEA1 N/A 0.025 0.025
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.025 0.075
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
SEC13L1 N/A 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.047
C20orf77 N/A 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.025
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.075
HTATIP N/A 0.025 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.025 0.075
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.044
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.148
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.098
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.044
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.098
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.075
BRD4 N/A 0.025 0.025
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.025
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.044
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.075
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.044
PRKCB1 N/A 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.025 0.075
GRK6 N/A 0.025 0.025
NUP98 N/A 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
RNF20 0.025 0.075
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.025 0.075
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.075
SON 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
0.228
Total Score 8.86