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Evidence of Interaction Between SNRPG and KIAA0788

The interaction score between SNRPG and KIAA0788 is 28.20.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between SNRPG and KIAA0788 = 0.78

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 0.013
Orthology
OrganismSNRPG OrthologueKIAA0788 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YFL017W-A 1 YER172C 1
  • CoPurification

Get References From PubMed
worm Q9N4G9 1 Q9U2G0 1
fly Q9VXE0 1 Q9VUV9 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.593
Domains Domains present in SNRPG and KIAA0788:
Domains in SNRPGDomains in KIAA0788
IPR001163 Small nuclear ribonucleoprotein (Sm protein)
IPR010920 Small nuclear-like ribonucleoprotein
IPR006649 snRNP domain
IPR001410 DEAD/DEAH box helicase
IPR001650 Helicase, C-terminal
IPR004179 Sec63 domain
IPR011545 DEAD/DEAH_N.

The Chi square scores for co-occurrence of domains that are present in SNRPG and KIAA0788 are listed below.

Domain 1Domain 2Chi Square
IPR010920 Small nuclear-like ribonucleoprotein IPR001410 DEAD/DEAH box helicase 54.2779
IPR006649 snRNP domain IPR001410 DEAD/DEAH box helicase 48.949
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR001410 DEAD/DEAH box helicase 47.7536
IPR010920 Small nuclear-like ribonucleoprotein IPR011545 DEAD/DEAH_N. 32.4775
IPR006649 snRNP domain IPR011545 DEAD/DEAH_N. 28.8609
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR011545 DEAD/DEAH_N. 28.0511
IPR010920 Small nuclear-like ribonucleoprotein IPR001650 Helicase, C-terminal 22.3985
IPR006649 snRNP domain IPR001650 Helicase, C-terminal 19.7813
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR001650 Helicase, C-terminal 19.1958

The background colour of the table refers to:

  • Blue Domain is only present in SNRPG
  • Yellow Domain is only present in KIAA0788
  • Green Domain is present in both SNRPG and KIAA0788

 0.027
Post-translational Modifications

Protein: SNRPG

PTMResidueReference

Protein: KIAA0788

PTMResidueReference
Phosphorylation 225 PubMed, HPRD
Phosphorylation 756 PubMed, HPRD
Phosphoserine 225 HPRD
Phosphoserine 756 HPRD
Localisation

Protein: SNRPG

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: KIAA0788

LocalisationReference
Nucleus HPRD
Nucleoplasm HPRD
Transitive Score

The common interactors between SNRPG and KIAA0788 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between SNRPG andKIAA0788. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , SNRPG has 256 interactors and KIAA0788 has 1175 interactors of which there are 127 common interactors.

Common InteractorName of Common InteractorScore for SNRPG-Interactor (?)Score for KIAA0788-Interactor (?)
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 2.07E3 202.00
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 2.07E3 431.00
SNRPD2 SNRPD2, SNRPD1: Small nuclear ribonucleoprotein Sm D2 691.00 32.60
LSM5 LSM5: U6 snRNA-associated Sm-like protein LSm5 691.00 68.20
LSM4 LSM4: U6 snRNA-associated Sm-like protein LSm4 691.00 32.60
PRPF4 PRPF4, PRP4: U4/U6 small nuclear ribonucleoprotein Prp4 69.60 14.00
PRP19 PRPF19, NMP200, PRP19, SNEV: Pre-mRNA-processing factor 19 25.60 11.10
SNRPE SNRPE: Small nuclear ribonucleoprotein E 8.73 0.137
PLRG1 PLRG1: Pleiotropic regulator 1 6.33 1.28
SNRPA1 SNRPA1: U2 small nuclear ribonucleoprotein A' 3.89 3.89
SF3B3 N/A 3.89 1.82
SART1 SART1: U4/U6.U5 tri-snRNP-associated protein 1 3.05 5.94
SNRPB SNRPB, COD, SNRPB1: Small nuclear ribonucleoprotein-associated proteins B and B' 2.91 0.137
LSM8 LSM8: U6 snRNA-associated Sm-like protein LSm8 2.60 0.257
LSM7 LSM7: U6 snRNA-associated Sm-like protein LSm7 2.60 69.60
SNRPF SNRPF, PBSCF: Small nuclear ribonucleoprotein F 2.60 19.70
LSM3 LSM3, MDS017: U6 snRNA-associated Sm-like protein LSm3 2.60 68.20
SF3A3 SF3A3, SAP61: Splicing factor 3A subunit 3 1.84 26.80
PRPF8 PRPF8, PRPC8: Pre-mRNA-processing-splicing factor 8 1.84 3.05
TXNL4A TXNL4A, DIM1, TXNL4: Thioredoxin-like protein 4A 1.82 6.05
PRPF3 PRPF3, HPRP3, PRP3: U4/U6 small nuclear ribonucleoprotein Prp3 1.49 3.05
LSM6 LSM6: U6 snRNA-associated Sm-like protein LSm6 1.22 32.60
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 1.22 122.00
LSM1 LSM1, CASM: U6 snRNA-associated Sm-like protein LSm1 1.22 0.074
PRPF31 PRPF31, PRP31: U4/U6 small nuclear ribonucleoprotein Prp31 1.10 3.89
PRPF6 PRPF6, C20orf14: Pre-mRNA-processing factor 6 0.890 1.82
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.890 136.00
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.657 102.00
LUC7L N/A 0.593 0.593
SF3B2 SF3B2, SAP145: Splicing factor 3B subunit 2 0.593 12.20
SF3A1 SF3A1, SAP114: Splicing factor 3 subunit 1 0.412 9.98
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.354 6.64
SNRPEL1 RP11-390F4.1-001: Small nuclear ribonucleoprotein polypeptide E-like protein 1. 0.354 0.354
CROP CROP, CREAP1, O48: Cisplatin resistance-associated overexpressed protein 0.300 1.31
DDX21 DDX21: Nucleolar RNA helicase 2 0.293 0.430
DHX15 DHX15, DBP1, DDX15: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase 0.293 0.090
RBBP4 RBBP4, RBAP48: Histone-binding protein RBBP4 0.263 0.139
NUP43 N/A 0.263 0.053
CDC20 CDC20: Cell division cycle protein 20 homolog 0.263 0.118
EIF4A1 EIF4A1, DDX2A, EIF4A: Eukaryotic initiation factor 4A-I 0.263 0.038
BAT1 N/A 0.263 0.081
DDX1 DDX1: ATP-dependent RNA helicase DDX1 0.263 0.038
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.263 0.385
TFIP11 TFIP11, HSPC006: Tuftelin-interacting protein 11 0.249 4.67
GNB2L1 Lung cancer oncogene 7 0.137 0.269
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.137 0.917
DDX50 DDX50: ATP-dependent RNA helicase DDX50 0.137 0.090
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.137 0.917
GTF3C2 GTF3C2, KIAA0011: General transcription factor 3C polypeptide 2 0.137 0.059
SEC13L1 SEC13, D3S1231E, SEC13L1, SEC13R: Protein SEC13 homolog 0.137 0.0278
WDR41 N/A 0.137 0.0278
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.123 0.241
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.123 0.078
DDX19A DDX19A, DDX19L: ATP-dependent RNA helicase DDX19A 0.123 0.081
DDX18 DDX18: ATP-dependent RNA helicase DDX18 0.123 0.081
DDX49 DDX49: Probable ATP-dependent RNA helicase DDX49 0.123 0.038
WDR68 WDR68, HAN11: WD repeat-containing protein 68 0.123 0.053
DDX23 DDX23: Probable ATP-dependent RNA helicase DDX23 0.123 0.242
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.123 0.118
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.123 0.146
DDX47 E4-DBP: DEAD box protein 0.123 0.081
DDX39 DDX39: ATP-dependent RNA helicase DDX39 0.123 0.038
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.123 0.241
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.123 0.146
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.123 0.241
LOC652595 RP11-395L14.12-001: OTTHUMP00000045488 0.119 0.119
NULL N/A 0.119 0.119
LUC7L2 N/A 0.119 0.119
NULL N/A 0.119 0.119
LOC645472 hCG_23490: Uncharacterized protein ENSP00000329276 0.119 0.119
NULL N/A 0.119 0.119
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.083 0.260
FBXW2 FBXW2, FBW2, FWD2: F-box/WD repeat-containing protein 2 0.083 0.059
SMARCAL1 SMARCAL1, HARP: SWI/SNF-related matrix-associated actin-dependent regulator of c 0.083 0.042
PTGES3 PTGES3, P23, TEBP: Prostaglandin E synthase 3 0.082 0.053
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.074 0.385
SEC31L1 N/A 0.074 0.118
DDX54 DDX54: ATP-dependent RNA helicase DDX54 0.074 0.038
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.074 0.822
COPB2 COPB2: Coatomer subunit beta' 0.074 0.118
COPA COPA: Coatomer subunit alpha 0.074 0.146
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.074 0.461
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.074 0.188
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.074 0.188
DDX27 DDX27, RHLP, HSPC259, PP3241: Probable ATP-dependent RNA helicase DDX27 0.074 0.081
RECQL RECQL, RECQL1: ATP-dependent DNA helicase Q1 0.074 0.038
CORO1C CORO1C, CRNN4: Coronin-1C 0.074 0.087
LOC119358 similar to small nuclear ribonucleoprotein D2 0.071 0.071
WDR8 WDR8: WD repeat-containing protein 8 0.067 0.0278
WDR1 N/A 0.067 0.163
PLK3 PLK3, CNK, FNK, PRK: Serine/threonine-protein kinase PLK3 0.065 0.108
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.060 0.071
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.060 0.046
DHX38 DHX38, DDX38, KIAA0224, PRP16: Pre-mRNA-splicing factor ATP-dependent RNA helica 0.060 10.00
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.060 0.385
DDX17 DDX17: Probable ATP-dependent RNA helicase DDX17 0.060 0.081
EXOSC8 EXOSC8, OIP2, RRP43: Exosome complex exonuclease RRP43 0.057 0.231
PLK2 PLK2, SNK: Serine/threonine-protein kinase PLK2 0.053 0.0421
EXOSC7 EXOSC7, KIAA0116, RRP42: Exosome complex exonuclease RRP42 0.051 0.0968
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.044 0.233
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.044 0.118
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.044 0.118
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.044 0.118
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.044 0.385
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.044 0.118
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.044 0.139
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.044 0.233
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.044 0.188
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.044 0.385
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.044 0.276
PHF20 PHF20, C20orf104, GLEA2, HCA58, NZF, TZP: PHD finger protein 20 0.039 0.027
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.036 0.043
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.036 0.188
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.036 0.233
NUP214 N/A 0.0308 0.060
DYNC1I2 N/A 0.028 0.043
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.028 0.069
HNRPD N/A 0.027 0.027
C11orf58 SMAP, C11orf58: Small acidic protein 0.027 0.053
NOLC1 NOLC1, KIAA0035: Nucleolar phosphoprotein p130 0.027 0.025
BUB3 N/A 0.027 0.027
DKFZP586L0724 NOL11, L14: Nucleolar protein 11 0.027 0.027
CEP57 CEP57, KIAA0092, TSP57: Centrosomal protein of 57 kDa 0.027 0.027
KARS KARS, KIAA0070: Lysyl-tRNA synthetase 0.027 0.231
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.027 0.083
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.027 0.052
WDR54 N/A 0.027 0.052
2.15E-3
Total Score 28.20