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Evidence of Interaction Between SNRPG and DDX43

The interaction score between SNRPG and DDX43 is 2.85.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismSNRPG OrthologueDDX43 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
worm Q9N4G9 1 Q9XVZ6 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in SNRPG and DDX43:
Domains in SNRPGDomains in DDX43
IPR001163 Small nuclear ribonucleoprotein (Sm protein)
IPR010920 Small nuclear-like ribonucleoprotein
IPR006649 snRNP domain
IPR000629 ATP-dependent helicase, DEAD-box
IPR001410 DEAD/DEAH box helicase
IPR001650 Helicase, C-terminal
IPR004087 KH
IPR004088 KH, type 1
IPR011545 DEAD/DEAH_N.

The Chi square scores for co-occurrence of domains that are present in SNRPG and DDX43 are listed below.

Domain 1Domain 2Chi Square
IPR010920 Small nuclear-like ribonucleoprotein IPR000629 ATP-dependent helicase, DEAD-box 129.429
IPR006649 snRNP domain IPR000629 ATP-dependent helicase, DEAD-box 117.853
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR000629 ATP-dependent helicase, DEAD-box 115.254
IPR010920 Small nuclear-like ribonucleoprotein IPR001410 DEAD/DEAH box helicase 54.2779
IPR006649 snRNP domain IPR001410 DEAD/DEAH box helicase 48.949
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR001410 DEAD/DEAH box helicase 47.7536
IPR010920 Small nuclear-like ribonucleoprotein IPR011545 DEAD/DEAH_N. 32.4775
IPR006649 snRNP domain IPR011545 DEAD/DEAH_N. 28.8609
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR011545 DEAD/DEAH_N. 28.0511
IPR010920 Small nuclear-like ribonucleoprotein IPR001650 Helicase, C-terminal 22.3985
IPR006649 snRNP domain IPR001650 Helicase, C-terminal 19.7813
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR001650 Helicase, C-terminal 19.1958

The background colour of the table refers to:

  • Blue Domain is only present in SNRPG
  • Yellow Domain is only present in DDX43
  • Green Domain is present in both SNRPG and DDX43

 0.027
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation

Protein: SNRPG

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: DDX43

No localisation data was used in calculating likelihood of interaction
Transitive Score

The common interactors between SNRPG and DDX43 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between SNRPG andDDX43. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , SNRPG has 256 interactors and DDX43 has 93 interactors of which there are 5 common interactors.

Common InteractorName of Common InteractorScore for SNRPG-Interactor (?)Score for DDX43-Interactor (?)
SNRPE SNRPE: Small nuclear ribonucleoprotein E 8.73 0.027
SNRPB SNRPB, COD, SNRPB1: Small nuclear ribonucleoprotein-associated proteins B and B' 2.91 0.027
LSM10 LSM10: U7 snRNA-associated Sm-like protein LSm10 0.237 0.027
LSM11 LSM11: U7 snRNA-associated Sm-like protein LSm11 0.237 0.027
DDX53 DDX53, CAGE: Probable ATP-dependent RNA helicase DDX53 0.027 0.027
0.299
Total Score 2.85