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Evidence of Interaction Between SNRPG and PLRG1

The interaction score between SNRPG and PLRG1 is 5.48.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismSNRPG OrthologuePLRG1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YFL017W-A 1 YPL151C 1
  • Other
  • AffinityCaptureMS

Get References From PubMed
worm Q9N4G9 1 Q18295 1
fly Q9VXE0 1 Q9VYQ9 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.593
Domains Domains present in SNRPG and PLRG1:
Domains in SNRPGDomains in PLRG1
IPR001163 Small nuclear ribonucleoprotein (Sm protein)
IPR010920 Small nuclear-like ribonucleoprotein
IPR006649 snRNP domain
IPR001680 G-protein beta WD-40 repeat
IPR011048 Cytochrome cd1-nitrite reductase-like, C-terminal haem d1

The Chi square scores for co-occurrence of domains that are present in SNRPG and PLRG1 are listed below.

Domain 1Domain 2Chi Square
IPR010920 Small nuclear-like ribonucleoprotein IPR001680 G-protein beta WD-40 repeat 22.3132
IPR006649 snRNP domain IPR001680 G-protein beta WD-40 repeat 19.3621
IPR001163 Small nuclear ribonucleoprotein (Sm protein) IPR001680 G-protein beta WD-40 repeat 18.7041

The background colour of the table refers to:

  • Blue Domain is only present in SNRPG
  • Yellow Domain is only present in PLRG1
  • Green Domain is present in both SNRPG and PLRG1

 0.027
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation

Protein: SNRPG

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: PLRG1

LocalisationReference
Nucleus HPRD
Nucleolus HPRD
Transitive Score

The common interactors between SNRPG and PLRG1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between SNRPG andPLRG1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , SNRPG has 256 interactors and PLRG1 has 50 interactors of which there are 16 common interactors.

Common InteractorName of Common InteractorScore for SNRPG-Interactor (?)Score for PLRG1-Interactor (?)
SNRPD2 SNRPD2, SNRPD1: Small nuclear ribonucleoprotein Sm D2 691.00 6.33
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 32.60 1.28
PRP19 PRPF19, NMP200, PRP19, SNEV: Pre-mRNA-processing factor 19 25.60 0.196
SNRPE SNRPE: Small nuclear ribonucleoprotein E 8.73 0.027
SNRPA1 SNRPA1: U2 small nuclear ribonucleoprotein A' 3.89 0.354
SNRPB SNRPB, COD, SNRPB1: Small nuclear ribonucleoprotein-associated proteins B and B' 2.91 0.027
SNRPF SNRPF, PBSCF: Small nuclear ribonucleoprotein F 2.60 6.33
PRPF8 PRPF8, PRPC8: Pre-mRNA-processing-splicing factor 8 1.84 0.593
SF3A2 SF3A2, SAP62: Splicing factor 3A subunit 2 1.84 0.593
SF3B2 SF3B2, SAP145: Splicing factor 3B subunit 2 0.593 0.593
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.354 0.354
TFIP11 TFIP11, HSPC006: Tuftelin-interacting protein 11 0.249 0.08
LOC652595 RP11-395L14.12-001: OTTHUMP00000045488 0.119 0.119
LOC119358 similar to small nuclear ribonucleoprotein D2 0.071 0.071
PLK3 PLK3, CNK, FNK, PRK: Serine/threonine-protein kinase PLK3 0.065 0.071
PLK2 PLK2, SNK: Serine/threonine-protein kinase PLK2 0.053 0.071
2.15E-3
Total Score 5.48