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Evidence of Interaction Between EPOR and MAPK3

The interaction score between EPOR and MAPK3 is 5.09.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between EPOR and MAPK3 = 0.00

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.85E-3
Orthology N/A N/A
Domains Domains present in EPOR and MAPK3:
Domains in EPORDomains in MAPK3
IPR003961 Fibronectin, type III
IPR003528 Long hematopoietin receptor, single chain
IPR009167 Erythropoietin receptor
IPR002996 Cytkn_recept_B/G.
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008351 JNK MAP kinase
IPR008349 ERK1/2 MAP kinase

The Chi square scores for co-occurrence of domains that are present in EPOR and MAPK3 are listed below.

Domain 1Domain 2Chi Square
IPR003961 Fibronectin, type III IPR008271 Serine/threonine protein kinase, active site 30.5883
IPR003961 Fibronectin, type III IPR002290 Serine/threonine protein kinase 13.198
IPR003528 Long hematopoietin receptor, single chain IPR011009 Protein kinase-like 3.32619
IPR002996 Cytkn_recept_B/G. IPR002290 Serine/threonine protein kinase 2.93674
IPR003528 Long hematopoietin receptor, single chain IPR000719 Protein kinase 1.94307
IPR002996 Cytkn_recept_B/G. IPR011009 Protein kinase-like 1.93327
IPR003961 Fibronectin, type III IPR008349 ERK1/2 MAP kinase 1.72177
IPR002996 Cytkn_recept_B/G. IPR000719 Protein kinase 1.43014
IPR009167 Erythropoietin receptor IPR000719 Protein kinase 0.93762
IPR003961 Fibronectin, type III IPR000719 Protein kinase 0.712801
IPR003961 Fibronectin, type III IPR011009 Protein kinase-like 0.616354
IPR009167 Erythropoietin receptor IPR011009 Protein kinase-like 0.331462
IPR003961 Fibronectin, type III IPR003527 MAP kinase 0.246402
IPR003961 Fibronectin, type III IPR008351 JNK MAP kinase 0.00406209

The background colour of the table refers to:

  • Blue Domain is only present in EPOR
  • Yellow Domain is only present in MAPK3
  • Green Domain is present in both EPOR and MAPK3

 0.049
Post-translational Modifications

Protein: EPOR

PTMResidueReference
Phosphorylation 368 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 454 PubMed, HPRD
Phosphorylation 456 PubMed, HPRD
Phosphorylation 468 PubMed, HPRD
Phosphorylation 485 PubMed, HPRD
Phosphorylation 489 PubMed, HPRD
Phosphorylation 504 PubMed, HPRD

Protein: MAPK3

PTMResidueReference
Phosphorylation 202 PubMed, HPRD
Phosphorylation 204 PubMed, HPRD
Phosphothreonine 202 PubMed, HPRD
Phosphotyrosine 204 PubMed, HPRD
Localisation

Protein: EPOR

LocalisationReference
ER HPRD
Plasma membrane HPRD
Secreted HPRD

Protein: MAPK3

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD
Transitive Score

The common interactors between EPOR and MAPK3 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EPOR andMAPK3. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EPOR has 1024 interactors and MAPK3 has 1361 interactors of which there are 490 common interactors.

Common InteractorName of Common InteractorScore for EPOR-Interactor (?)Score for MAPK3-Interactor (?)
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 3.59 0.055
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.541 0.062
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.340 0.111
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.251 0.055
HSP90AA1 Hsp89-alpha-delta-N 0.202 0.069
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.032
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.166 0.050
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.166 0.114
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.166 0.056
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.165 0.098
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.049
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.165 46.90
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.049
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.049
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.098
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.098
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.049
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.153 0.069
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.153 0.049
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.152 0.029
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.152 0.041
KIT KIT: Mast/stem cell growth factor receptor precursor 0.152 0.041
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.127 41.40
TAL1 TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1 0.126 0.049
RDX RDX: Radixin 0.126 0.136
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.126 0.114
GAB1 GAB1: GRB2-associated-binding protein 1 0.126 0.123
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.126 0.136
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.126 0.056
CD2AP CD2AP: CD2-associated protein 0.126 0.049
CRKL CRKL: Crk-like protein 0.126 0.111
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.126 0.037
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.124 0.044
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.124 0.043
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.037
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.123 0.029
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.123 0.026
IL9R IL9R: Interleukin-9 receptor precursor 0.123 0.029
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.123 0.090
GHR GHR: Growth hormone receptor precursor 0.123 0.032
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.064
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.075
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.109 0.075
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.075
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.075
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 0.165
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.075
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 0.075
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.148
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.083
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.109 33.30
ARHGEF7 N/A 0.109 0.148
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.109 0.148
ELMO1 N/A 0.109 0.148
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.034
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.109 33.30
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 0.165
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.075
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.148
NF2 NF2, SCH: Merlin 0.109 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.165
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 0.075
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.109 0.148
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.083
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 0.148
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.148
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.075
STAT3 0.109 0.148
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.109 0.148
MAPK15 N/A 0.109 0.083
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 0.148
PSCD2 N/A 0.109 0.165
F3 F3: Tissue factor precursor 0.109 0.032
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.0453
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.033
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.109 0.051
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.109 0.033
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.037
ITGB4 N/A 0.109 0.032
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.109 0.029
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.109 0.032
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.0453
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.109 0.033
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.109 0.097
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.109 0.148
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.037
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.109 0.032
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.109 0.0727
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.049
PRLR PRLR: Prolactin receptor precursor 0.109 0.033
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.105 0.191
PLD2 PLD2: Phospholipase D2 0.100 0.111
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.100 0.874
DOK1 DOK1: Docking protein 1 0.100 0.136
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.055
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.100 112.00
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.049
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.100 0.097
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.100 0.111
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.100 0.136
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.100 0.086
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.100 0.056
RPS6KB1 N/A 0.100 0.056
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.100 0.275
NEO1 NEO1, NGN: Neogenin precursor 0.098 0.051
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.098 0.026
PTPRZ1 N/A 0.098 0.148
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.029
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.098 0.073
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.091 0.056
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.091 0.055
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.091 0.049
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.091 0.049
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.087 0.033
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.083 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.083 0.049
EDA N/A 0.083 0.049
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.075
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.083 0.098
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.083 0.044
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.083 0.109
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.081 0.056
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.081 0.136
DLG2 DLG2: Disks large homolog 2 0.081 0.035
SORBS3 SORBS3, SCAM1: Vinexin 0.081 0.069
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.123
STK16 N/A 0.081 0.055
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.081 0.069
SYK SYK: Tyrosine-protein kinase SYK 0.081 0.111
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.081 0.097
STAT6 STAT6: Signal transducer and activator of transcription 6 0.081 65.60
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.081 0.111
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.098
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.191
TLN2 TLN2: Uncharacterized protein TLN2 0.081 0.029
RIN1 RIN1: Ras and Rab interactor 1 0.081 0.136
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 108.00
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.081 0.114
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.081 0.152
HCK N/A 0.081 0.136
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.081 0.097
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.081 0.171
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.081 0.062
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.081 0.097
WEE1 WEE1: Wee1-like protein kinase 0.075 0.050
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.075 0.049
CDK2 CDK2: Cell division protein kinase 2 0.075 2.30
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.075 0.050
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.075 0.056
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.075 0.069
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.074 0.026
SPTAN1 N/A 0.0727 0.155
ROCK1 ROCK1: Rho-associated protein kinase 1 0.072 0.109
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.072 0.097
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.072 0.111
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.072 0.109
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.072 10.80
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.072 0.114
VIL2 N/A 0.072 0.111
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 0.077
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.072 0.123
GAB2 N/A 0.072 0.251
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 0.097
BMX N/A 0.072 0.098
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.072 0.057
LYN LYN: Tyrosine-protein kinase Lyn 0.072 0.136
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.152
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.072 0.097
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.069
MSN MSN: Moesin 0.072 0.136
VAV1 VAV1, VAV: Proto-oncogene vav 0.072 0.111
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.072 0.056
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.072 0.111
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.072 0.056
FNBP1 N/A 0.072 0.069
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.072 0.136
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.072 0.069
PLD1 PLD1: Phospholipase D1 0.072 0.088
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.072 0.097
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.086
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.086
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.072 0.109
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.072 0.056
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.072 0.225
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.072 0.123
JAK1 0.072 0.136
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.072 0.123
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.109
CSK CSK: Tyrosine-protein kinase CSK 0.072 0.111
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.072 0.191
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.062
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.123
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.109
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.077
IRS1 IRS1: Insulin receptor substrate 1 0.072 0.123
CXorf9 N/A 0.072 0.049
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.062
PSD TYL: TYL protein 0.072 0.225
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.072 0.136
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.072 0.111
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.062
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.072 65.60
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.098
PSCD4 PSCD4, CYT4: Cytohesin-4 0.072 0.111
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.072 0.136
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.109
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 71.20
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.075
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.0688 33.30
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.136
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.065 0.225
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.372
APS SH2B2, APS: SH2B adapter protein 2 0.065 0.111
NCK2 NCK2: Cytoplasmic protein NCK2 0.065 0.225
RASA3 RASA3: Ras GTPase-activating protein 3 0.065 0.111
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.225
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.275
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.065 0.044
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.171
F8 F8, F8C: Coagulation factor VIII precursor 0.065 0.025
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.065 0.171
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.065 54.60
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 0.098
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.096
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.152
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.065 0.032
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.111
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 53.10
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.062 0.027
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.062 0.041
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.062 0.073
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.062 0.029
CD44 N/A 0.062 0.0453
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.062 0.029
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.062 0.027
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.029
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.062 0.049
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.062 0.0453
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.061 0.029
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.057 0.049
CDK6 CDK6: Cell division protein kinase 6 0.057 0.049
DYRK3 N/A 0.057 0.049
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.057 0.069
CDK4 CDK4: Cell division protein kinase 4 0.057 0.049
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 82.20
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.056 0.114
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.055 0.026
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.055 0.081
EGF EGF: Pro-epidermal growth factor precursor 0.055 0.029
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.055 0.032
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.055 0.029
GRB10 N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.051 0.046
PTPRA N/A 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.046
RAPH1 N/A 0.051 0.051
C9orf88 N/A 0.051 0.051
EPB41 EPB41, E41P: Protein 4.1 0.051 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.051 0.046
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.051 0.046
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.097
TP73 TP73, P73: Tumor protein p73 0.051 0.056
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.051 38.50
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.0513 0.056
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.049 0.027
SLITRK5 SLITRK5, KIAA0918, LRRC11: SLIT and NTRK-like protein 5 precursor 0.049 0.027
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.049 0.126
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 35.90
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.083
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.075
SNX3 N/A 0.049 0.075
CNN2 CNN2: Calponin-2 0.049 0.075
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.075
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.083
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.075
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.049 0.075
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.075
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.075
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.083
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.075
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.049 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.083
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.075
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.049 0.025
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.083
MAPKAPK5 N/A 0.049 0.083
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.083
ACTN4 ACTN4: Alpha-actinin-4 0.049 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.049 0.025
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.148
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.083
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.049 0.075
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.049 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.049 0.025
PPEF1 N/A 0.049 0.028
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.075
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.075
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.075
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.049 0.025
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.083
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.075
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.083
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.075
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 35.90
MAP2K5 N/A 0.049 0.165
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.047 0.030
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.046 1.98
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.0453 0.049
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.0453 53.10
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.0453 153.00
DAB1 DAB1: Disabled homolog 1 0.0453 0.088
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.0453 0.069
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.062
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.0453 0.029
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.062
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.0453 0.056
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0453 0.096
STAT2 STAT2: Signal transducer and activator of transcription 2 0.045 0.109
PLEK PLEK, P47: Pleckstrin 0.045 0.123
SOS1 SOS1: Son of sevenless homolog 1 0.045 0.111
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.045 0.111
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.098
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.045 0.152
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.0446 0.056
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.044 0.050
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.042 0.056
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.173
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.171
STAT4 STAT4: Signal transducer and activator of transcription 4 0.041 0.097
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 30.70
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.04 0.025
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.04 0.075
CDC20 CDC20: Cell division cycle protein 20 homolog 0.039 0.044
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.039 0.057
XRCC1 XRCC1: DNA-repair protein XRCC1 0.039 0.026
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.038 0.042
COPA COPA: Coatomer subunit alpha 0.037 0.029
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.037 0.077
VASP VASP: Vasodilator-stimulated phosphoprotein 0.037 0.152
STK10 STK10: Uncharacterized protein STK10 0.037 0.069
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.037 0.056
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.037 0.056
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.037 0.069
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.026
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.114
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.037 0.062
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.037 0.044
CDK7 CDK7, MO15: Cell division protein kinase 7 0.037 0.049
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.037 0.062
FLII FLII, FLIL: Protein flightless-1 homolog 0.037 0.029
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.037 0.032
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.037 0.026
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.037 0.111
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.037 0.056
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.037 0.139
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.077
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.037 0.114
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.037 0.086
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.037 0.097
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.037 0.086
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.037 0.038
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.037 0.044
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.037 0.069
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.037 0.026
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.036 0.031
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.034 0.029
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.034 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.034 0.025
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.075
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 35.90
CETN1 CETN1, CEN1, CETN: Centrin-1 0.034 0.025
NDP NDP: Norrin precursor 0.033 0.063
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 65.60
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.062
MYO3A MYO3A: Myosin IIIA 0.032 0.044
DAPK2 DAPK2: Death-associated protein kinase 2 0.032 0.062
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.032 0.046
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.069
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.032 0.049
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.114
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.086
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.056
S100B S100B: Protein S100-B 0.032 0.026
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.032 0.063
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.062
GRLF1 N/A 0.032 0.077
VWF VWF, F8VWF: von Willebrand factor precursor 0.032 0.057
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 33.10
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.032 0.029
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.055
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.032 3.51
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.032 0.040
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.062
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.032 0.225
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.032 0.038
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.032 0.114
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.032 41.40
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.032 0.049
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.032 0.056
DAB2 DAB2, DOC2: Disabled homolog 2 0.032 0.111
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.069
PRKAA1 N/A 0.032 0.055
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.032 0.114
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.032 0.136
ATM ATM: Serine-protein kinase ATM 0.032 0.056
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.032 0.056
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.026
GMIP GMIP: GEM-interacting protein 0.032 0.069
CDKL5 N/A 0.032 0.055
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.062
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.032 0.086
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.032 0.049
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.032 0.114
TP53 TP53, P53: Cellular tumor antigen p53 0.031 0.049
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.031 0.038
DYNC1I2 N/A 0.030 0.038
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.030 0.029
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.086
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.029 0.139
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.049
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.069
CDK5 CDK5: Cell division protein kinase 5 0.029 0.139
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.049
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.029 0.086
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.086
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.029 0.045
CNN3 CNN3: Calponin-3 0.029 0.069
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.029 0.0425
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.029 0.056
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.225
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.029 0.044
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.029 0.050
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.114
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.029 0.035
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.029 0.033
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.049
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.028 0.049
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.049
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.098
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.044
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.049
AQP4 AQP4: Aquaporin-4 0.028 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.028 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.044
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.049
TBXA2R TBXA2R: Thromboxane A2 receptor 0.028 0.04
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.028 0.049
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.028 0.04
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 1 0.028 0.366
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.028 0.044
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.049
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.028 0.049
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.049
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
THOC1 THOC1, HPR1: THO complex subunit 1 0.027 0.049
AQP1 AQP1, CHIP28: Aquaporin-1 0.027 0.056
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.0263 0.038
CIITA CIITA, MHC2TA: MHC class II transactivator 0.0263 0.055
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.026 0.509
RHO RHO, OPN2: Rhodopsin 0.026 0.033
FADD FADD, MORT1: Protein FADD 0.026 0.0453
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.025 0.111
ETS2 ETS2: Protein C-ets-2 0.025 0.191
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.025 0.056
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.055
NUP214 N/A 0.025 0.026
0.347
Total Score 5.09