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Evidence of Interaction Between EPOR and CBLB

The interaction score between EPOR and CBLB is 5.40.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between EPOR and CBLB = -0.05

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.62E-3
Orthology N/A N/A
Domains Domains present in EPOR and CBLB:
Domains in EPORDomains in CBLB
IPR003961 Fibronectin, type III
IPR003528 Long hematopoietin receptor, single chain
IPR009167 Erythropoietin receptor
IPR002996 Cytkn_recept_B/G.
IPR001841 Zn-finger, RING
IPR000449 Ubiquitin-associated domain
IPR000980 SH2 motif
IPR003153 Adaptor protein Cbl, N-terminal
IPR011992 EF-Hand_type.

The Chi square scores for co-occurrence of domains that are present in EPOR and CBLB are listed below.

Domain 1Domain 2Chi Square
IPR002996 Cytkn_recept_B/G. IPR000980 SH2 motif 227.343
IPR003961 Fibronectin, type III IPR000980 SH2 motif 184.508
IPR003528 Long hematopoietin receptor, single chain IPR000980 SH2 motif 151.135
IPR009167 Erythropoietin receptor IPR000980 SH2 motif 38.4825
IPR002996 Cytkn_recept_B/G. IPR011992 EF-Hand_type. 9.08983
IPR003528 Long hematopoietin receptor, single chain IPR011992 EF-Hand_type. 0.995048
IPR003961 Fibronectin, type III IPR011992 EF-Hand_type. 0.00640738

The background colour of the table refers to:

  • Blue Domain is only present in EPOR
  • Yellow Domain is only present in CBLB
  • Green Domain is present in both EPOR and CBLB

 0.069
Post-translational Modifications

Protein: EPOR

PTMResidueReference
Phosphorylation 368 PubMed, HPRD
Phosphorylation 426 PubMed, HPRD
Phosphorylation 454 PubMed, HPRD
Phosphorylation 456 PubMed, HPRD
Phosphorylation 468 PubMed, HPRD
Phosphorylation 485 PubMed, HPRD
Phosphorylation 489 PubMed, HPRD
Phosphorylation 504 PubMed, HPRD

Protein: CBLB

PTMResidueReference
Phosphotyrosine 665 HPRD
Phosphotyrosine 709 HPRD
Localisation

Protein: EPOR

LocalisationReference
ER HPRD
Plasma membrane HPRD
Secreted HPRD

Protein: CBLB

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between EPOR and CBLB that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between EPOR andCBLB. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , EPOR has 1024 interactors and CBLB has 1522 interactors of which there are 533 common interactors.

Common InteractorName of Common InteractorScore for EPOR-Interactor (?)Score for CBLB-Interactor (?)
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 3.59 0.072
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.541 0.051
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.340 0.067
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.251 0.0416
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.210 0.027
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.041
CRLF3 N/A 0.191 0.046
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.166 0.111
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.166 0.073
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.166 0.225
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.483
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.165 0.062
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.483
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.165 0.483
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.165 0.062
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.540
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.165 0.062
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.0688
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.0688
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.0688
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.0688
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.0688
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.165 0.483
FN1 N/A 0.165 0.0688
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.0688
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.540
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.0688
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.0688
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.540
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.153 0.171
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.153 0.171
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.152 0.045
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.152 0.445
KIT KIT: Mast/stem cell growth factor receptor precursor 0.152 0.361
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.127 0.148
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.126 0.049
RDX RDX: Radixin 0.126 0.064
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.126 0.058
GAB1 GAB1: GRB2-associated-binding protein 1 0.126 0.123
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.126 1.33
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.126 0.275
CD2AP CD2AP: CD2-associated protein 0.126 0.181
CRKL CRKL: Crk-like protein 0.126 0.181
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.125 0.038
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.125 0.038
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.124 0.111
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.123 0.0794
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.123 0.286
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.123 0.046
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.123 0.361
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.123 0.323
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.123 0.318
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.123 0.045
INSR INSR: Insulin receptor precursor 0.123 0.318
IL9R IL9R: Interleukin-9 receptor precursor 0.123 0.051
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.123 0.361
GHR GHR: Growth hormone receptor precursor 0.123 0.063
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.110 0.114
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.109 0.098
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.109 0.148
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.098
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.109 0.098
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.109 0.543
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.109 0.050
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.109 0.098
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.109 0.098
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.109
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.109 0.148
ARHGEF7 N/A 0.109 0.098
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.109
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.109 0.098
ELMO1 N/A 0.109 0.148
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.109 0.148
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.109 0.109
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.109 0.980
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.109 0.148
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.109 0.109
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.109 0.098
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.109 0.098
NF2 NF2, SCH: Merlin 0.109 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.109 0.109
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.109 0.483
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.109 0.878
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.109
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.109 0.098
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.109
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.109 0.878
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.109
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.109 0.148
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.050
STAT3 0.109 0.098
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.109 18.00
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.109 0.148
MAPK15 N/A 0.109 0.165
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.109 0.878
PSCD2 N/A 0.109 0.109
F3 F3: Tissue factor precursor 0.109 0.045
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.0794
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.109 0.041
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.109 0.361
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.109 0.063
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.109 0.057
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 0.109 0.318
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.109 0.214
MET MET: Hepatocyte growth factor receptor precursor 0.109 0.320
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.109 0.320
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.109 0.361
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.109 0.128
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.109 0.214
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.109 0.286
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.109 0.065
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.109 0.360
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.109 0.045
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.051
SORL1 SORL1: Sortilin-related receptor precursor 0.109 0.037
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.109 0.128
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.109 0.126
PRLR PRLR: Prolactin receptor precursor 0.109 0.041
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.109 0.361
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.109 0.318
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.105 0.110
PLD2 PLD2: Phospholipase D2 0.100 0.073
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.100 0.275
DOK1 DOK1: Docking protein 1 0.100 0.225
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.416
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.100 0.148
STAM2 STAM2: Signal transducing adapter molecule 2 0.100 0.073
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.100 0.577
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.100 1.01
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.100 2.20
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.100 0.113
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.100 0.372
RPS6KB1 N/A 0.100 0.461
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.100 0.113
TLN1 TLN1: Uncharacterized protein TLN1 0.100 0.113
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.098 0.323
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.098 0.323
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.098 0.318
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.098 0.445
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.098 0.041
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.098 0.318
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.098 0.916
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.098 0.318
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.173
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.098 0.037
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.098 0.051
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.091 0.275
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.091 0.152
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.091 0.136
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.091 0.046
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.083 0.0688
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.083 0.0688
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.083 0.109
KIR3DL1 N/A 0.083 0.0688
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.083 0.062
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.083 0.0688
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.081 0.136
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.081 0.372
DLG2 DLG2: Disks large homolog 2 0.081 0.041
SORBS3 SORBS3, SCAM1: Vinexin 0.081 0.064
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.081 0.051
STK16 N/A 0.081 0.191
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.081 0.058
SYK SYK: Tyrosine-protein kinase SYK 0.081 1.33
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.081 0.340
STAT6 STAT6: Signal transducer and activator of transcription 6 0.081 0.245
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.081 0.181
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.081 0.081
IRS2 IRS2: Insulin receptor substrate 2 0.081 0.109
TLN2 TLN2: Uncharacterized protein TLN2 0.081 0.052
RIN1 RIN1: Ras and Rab interactor 1 0.081 0.037
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.081 0.113
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.081 0.372
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.081 0.202
HCK N/A 0.081 0.808
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.081 0.275
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.081 0.225
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.081 0.052
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.077 0.181
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.077 0.214
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.077 0.0794
WEE1 WEE1: Wee1-like protein kinase 0.075 0.136
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.075 0.097
CDK2 CDK2: Cell division protein kinase 2 0.075 0.171
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.075 0.171
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.075 0.372
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.075 0.372
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.075 0.046
SPTAN1 N/A 0.0727 0.065
ROCK1 ROCK1: Rho-associated protein kinase 1 0.072 0.307
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.072 0.655
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.072 9.65
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.072 0.166
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.072 0.192
TTN N/A 0.072 0.097
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.072 0.586
VIL2 N/A 0.072 0.148
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.072 0.274
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.072 0.340
GAB2 N/A 0.072 0.109
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.072 0.655
BMX N/A 0.072 0.581
LYN LYN: Tyrosine-protein kinase Lyn 0.072 1.33
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.072 0.191
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.072 9.65
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.072 0.088
MSN MSN: Moesin 0.072 0.304
VAV1 VAV1, VAV: Proto-oncogene vav 0.072 0.304
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.072 0.245
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.072 0.655
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.072 0.033
FNBP1 N/A 0.072 0.763
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.072 1.33
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.072 0.304
PLD1 PLD1: Phospholipase D1 0.072 0.090
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.072 0.503
CTTN CTTN, EMS1: Src substrate cortactin 0.072 0.058
ALK ALK: ALK tyrosine kinase receptor precursor 0.072 0.361
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.136
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.072 5.04
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.072 0.058
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.072 0.064
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.072 0.202
JAK1 0.072 4.52
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.072 0.902
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.072 0.037
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.072 0.340
CSK CSK: Tyrosine-protein kinase CSK 0.072 2.73
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.072 0.902
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.072 0.123
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.029
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.109
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.072 0.100
IRS1 IRS1: Insulin receptor substrate 1 0.072 0.109
CXorf9 N/A 0.072 0.461
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.072 0.307
PSD TYL: TYL protein 0.072 0.064
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.072 0.372
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.072 0.763
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.072 0.852
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.072 0.064
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.072 0.644
PSCD4 PSCD4, CYT4: Cytohesin-4 0.072 0.245
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.072 0.304
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.072 0.081
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.0688 0.148
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.0688 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.0688 0.148
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.067 0.179
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.065 0.099
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.065 0.461
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.065 0.058
APS SH2B2, APS: SH2B adapter protein 2 0.065 0.090
NCK2 NCK2: Cytoplasmic protein NCK2 0.065 0.245
RASA3 RASA3: Ras GTPase-activating protein 3 0.065 0.304
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.065 0.078
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.065 0.065
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.065 0.073
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.065 0.065
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.065 0.065
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.065 0.111
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.065 0.644
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.065 0.251
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.191
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.065 1.50
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.065 0.181
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 0.372
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.062 0.114
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.062 0.046
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.062 0.041
CD44 N/A 0.062 0.029
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.062 0.173
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.062 0.214
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.062 0.071
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.062 0.181
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.062 0.051
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.061 0.139
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.057 0.152
CDK6 CDK6: Cell division protein kinase 6 0.057 0.111
DYRK3 N/A 0.057 0.097
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.057 0.461
CDK4 CDK4: Cell division protein kinase 4 0.057 0.171
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.057 0.181
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.056 0.073
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.055 0.114
LILRB1 N/A 0.055 0.063
CD7 CD7: T-cell antigen CD7 precursor 0.055 0.076
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.055 0.046
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.055 0.076
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.055 0.041
ITGB7 ITGB7: Integrin beta-7 precursor 0.055 0.038
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.055 0.076
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.055 0.0794
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.055 0.046
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.055 0.0794
MEP1B MEP1B: Meprin A subunit beta precursor 0.055 0.041
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.055 0.128
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.055 0.063
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.055 0.0794
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.055 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.055 0.214
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
GRB10 N/A 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.051 0.046
PTPRA N/A 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.051 0.046
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.051 0.046
EPB41 EPB41, E41P: Protein 4.1 0.051 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.051 0.046
FLT4 VEGFR3 long form 0.051 1.37
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 1.53
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 1.53
CRK CRK: Proto-oncogene C-crk 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
VAV2 VAV2: Uncharacterized protein VAV2 0.051 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.051 0.046
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.051 0.553
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.051 0.097
TP73 TP73, P73: Tumor protein p73 0.051 0.109
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.051 0.191
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.0513 0.126
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.049 0.128
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.049 0.041
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.049 0.036
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.049 0.148
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.049 0.148
CNN2 CNN2: Calponin-2 0.049 0.044
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.049 0.148
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.049 0.165
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.049 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.049 0.044
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.049 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.049 0.148
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.109
CDC2 CDC2: Cell division control protein 2 homolog 0.049 0.148
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.049 0.165
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.049 0.165
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.165
MAPKAPK5 N/A 0.049 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.049 0.049
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.049 0.056
ACTN4 ACTN4: Alpha-actinin-4 0.049 0.098
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.049 0.036
EEF2K EEF2K: Elongation factor 2 kinase 0.049 0.148
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.049 0.044
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.049 0.044
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.049 0.036
PPEF1 N/A 0.049 0.056
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.049 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.049 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.049 0.148
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.049 0.165
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.049 0.148
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.109
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.049 0.050
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.049 0.148
MAP2K5 N/A 0.049 0.044
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.047 0.030
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.046 0.088
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.0453 0.046
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.0453 0.113
FUBP1 N/A 0.0453 0.253
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.0453 0.372
DAB1 DAB1: Disabled homolog 1 0.0453 0.097
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.0453 0.225
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.0407
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.0453 0.275
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.0453 0.123
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.0453 0.227
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.0453 0.063
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0453 0.191
STAT2 STAT2: Signal transducer and activator of transcription 2 0.045 0.191
PLEK PLEK, P47: Pleckstrin 0.045 0.416
SOS1 SOS1: Son of sevenless homolog 1 0.045 0.461
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.045 0.109
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.045 0.852
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.0446 0.090
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.0446 0.181
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.044 0.050
CENTA1 CENTA1: Centaurin-alpha 1 0.041 0.051
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.097
STAT4 STAT4: Signal transducer and activator of transcription 4 0.041 0.763
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.041 0.076
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.04 0.075
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.039 0.063
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.039 0.038
XRCC1 XRCC1: DNA-repair protein XRCC1 0.039 0.0425
COPA COPA: Coatomer subunit alpha 0.037 0.046
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.037 0.140
VASP VASP: Vasodilator-stimulated phosphoprotein 0.037 0.166
STK10 STK10: Uncharacterized protein STK10 0.037 1.62
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.037 0.461
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.037 0.225
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.037 0.097
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.037 0.032
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.037 0.051
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.037 0.416
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.051
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.037 0.111
CDK7 CDK7, MO15: Cell division protein kinase 7 0.037 0.171
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.037 0.251
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.037 0.046
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.037 0.090
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.037 1.62
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.037 0.111
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.037 0.123
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.037 0.111
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.037 0.111
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.037 0.029
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.037 0.148
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.037 0.461
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.037 0.067
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.037 0.099
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.037 0.171
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.036 0.030
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.034 0.041
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.0338 0.070
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.034 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.034 0.148
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.034 0.148
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.034 0.148
CETN1 CETN1, CEN1, CETN: Centrin-1 0.034 0.047
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.033 0.111
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.032 0.090
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.032 0.191
MYO3A MYO3A: Myosin IIIA 0.032 0.088
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.032 0.033
DAPK2 DAPK2: Death-associated protein kinase 2 0.032 0.123
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.032 0.027
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.032 0.304
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.032 0.097
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.032 0.225
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.032 0.073
ACTN1 ACTN1: Alpha-actinin-1 0.032 0.073
LCP1 LCP1, PLS2: Plastin-2 0.032 0.304
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.032 0.0735
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.032 0.027
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.287
GRLF1 N/A 0.032 0.062
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.032 0.051
VWF VWF, F8VWF: von Willebrand factor precursor 0.032 0.037
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.032 0.0296
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.032 0.416
S100A7 S100A7, PSOR1: Protein S100-A7 0.032 0.032
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.032 0.088
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.032 0.152
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.032 0.0308
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.032 0.097
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.032 0.088
CHP CHP: Calcium-binding protein p22 0.032 0.027
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.032 0.275
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.032 0.123
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.032 0.372
DAB2 DAB2, DOC2: Disabled homolog 2 0.032 0.111
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.032 0.109
PRKAA1 N/A 0.032 0.307
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.032 0.037
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.032 0.245
PMP2 PMP2: Myelin P2 protein 0.032 0.026
ATM ATM: Serine-protein kinase ATM 0.032 1.62
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.032 0.097
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.037
GMIP GMIP: GEM-interacting protein 0.032 0.0818
CDKL5 N/A 0.032 0.110
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.251
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.032 0.088
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.032 0.136
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.032 0.026
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.032 0.033
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.032 0.046
TP53 TP53, P53: Cellular tumor antigen p53 0.031 0.114
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.031 0.038
MDN1 MDN1, KIAA0301: Midasin 0.030 0.046
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.029 0.026
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.029 0.088
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.029 0.097
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.029 0.763
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.275
CDK5 CDK5: Cell division protein kinase 5 0.029 0.097
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.166
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.029 0.026
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.029 0.088
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.171
CNN3 CNN3: Calponin-3 0.029 0.065
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.029 0.046
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.029 0.027
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.029 0.064
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.065
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.029 0.037
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.029 0.123
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.029 0.088
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.029 0.088
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.029 0.058
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.0688
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.028 0.0688
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.0688
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.062
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.028 0.062
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.030
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.0688
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.030
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.062
DRD2 DRD2: D(2) dopamine receptor 0.028 0.034
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.028 0.030
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.028 0.0688
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.0688
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.217
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.027 0.126
FGFR2 N/A 0.027 0.141
RIOK3 RIOK3, SUDD: Serine/threonine-protein kinase RIO3 0.027 0.028
PIM1 N/A 0.027 0.036
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.027 0.029
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.027 0.033
THOC1 THOC1, HPR1: THO complex subunit 1 0.027 0.148
FADD FADD, MORT1: Protein FADD 0.026 0.128
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.025 0.058
ETS2 ETS2: Protein C-ets-2 0.025 0.123
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.025 0.372
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.025 0.191
GNB2L1 Lung cancer oncogene 7 0.025 0.052
0.299
Total Score 5.40