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Evidence of Interaction Between MAPK1 and HSP90AA1

The interaction score between MAPK1 and HSP90AA1 is 3.42.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and HSP90AA1 = 0.46

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 4.62E-3
Orthology
OrganismMAPK1 OrthologueHSP90AA1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YBL016W 1 YPL240C 0.622
bakers yeast YGR040W 0.096 YPL240C 0.622
  • Y2H

Get References From PubMed
worm P39745 1 Q18688 1
fly P40417 1 P02828 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.064
Domains Domains present in MAPK1 and HSP90AA1:
Domains in MAPK1Domains in HSP90AA1
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR001404 Heat shock protein Hsp90
IPR003594 ATP-binding region, ATPase-like
IPR009079 Four-helical cytokine

The Chi square scores for co-occurrence of domains that are present in MAPK1 and HSP90AA1 are listed below.

Domain 1Domain 2Chi Square
IPR008271 Serine/threonine protein kinase, active site IPR001404 Heat shock protein Hsp90 8.94866
IPR002290 Serine/threonine protein kinase IPR001404 Heat shock protein Hsp90 6.4752
IPR000719 Protein kinase IPR001404 Heat shock protein Hsp90 4.2459
IPR008271 Serine/threonine protein kinase, active site IPR003594 ATP-binding region, ATPase-like 4.24016
IPR011009 Protein kinase-like IPR001404 Heat shock protein Hsp90 2.85058
IPR002290 Serine/threonine protein kinase IPR003594 ATP-binding region, ATPase-like 2.02066
IPR008271 Serine/threonine protein kinase, active site IPR009079 Four-helical cytokine 1.14281
IPR002290 Serine/threonine protein kinase IPR009079 Four-helical cytokine 0.960208
IPR000719 Protein kinase IPR003594 ATP-binding region, ATPase-like 0.689782
IPR011009 Protein kinase-like IPR003594 ATP-binding region, ATPase-like 0.635233
IPR011009 Protein kinase-like IPR009079 Four-helical cytokine 0.0209035
IPR000719 Protein kinase IPR009079 Four-helical cytokine 0.00559597

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in HSP90AA1
  • Green Domain is present in both MAPK1 and HSP90AA1

 0.083
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: HSP90AA1

PTMResidueReference
Phosphorylation 127 PubMed, HPRD
Phosphorylation 129 PubMed, HPRD
Phosphorylation 353 PubMed, HPRD
Phosphorylation 385 PubMed, HPRD
Phosphoserine 230 HPRD
Phosphoserine 262 HPRD
Phosphothreonine 4 PubMed, HPRD
Phosphothreonine 6 PubMed, HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: HSP90AA1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between MAPK1 and HSP90AA1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andHSP90AA1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and HSP90AA1 has 1373 interactors of which there are 875 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for HSP90AA1-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 0.069
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.025
DIAPH1 Diaphanous 1 20.60 1.08
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 11.60 0.066
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 10.50 0.040
CDK2 CDK2: Cell division protein kinase 2 6.80 0.188
HSPD1 6.11 4.15
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 4.15 0.066
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 3.35 0.461
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.046
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 2.02 0.385
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 1.42 0.050
XRCC5 XRCC5, G22P2: ATP-dependent DNA helicase 2 subunit 2 0.622 0.428
RASGEF1B N/A 0.593 0.119
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.029
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.029
CRKL CRKL: Crk-like protein 0.461 0.063
JAK1 0.461 0.086
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.029
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.038
MSN MSN: Moesin 0.461 0.029
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.029
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.139
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.026
ELF1 ELF1: ETS-related transcription factor Elf-1 0.416 0.027
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.0453
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.188
STK10 STK10: Uncharacterized protein STK10 0.385 0.086
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.038
FAM82B FAM82B, CGI-90: Protein FAM82B 0.376 0.060
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.372 0.038
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.086
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.038
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.086
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 0.040
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.114
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.078
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.046
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.372 0.129
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 0.114
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.139
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 0.069
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.069
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.372 0.556
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.078
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.0446
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.032
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.127
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.026
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.275 0.078
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 0.086
DOK1 DOK1: Docking protein 1 0.275 0.029
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.139
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.051
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.086
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.275 0.056
HCK N/A 0.275 0.056
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 0.086
MAFG MAFG: Transcription factor MafG 0.275 0.032
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.275 0.078
SYK SYK: Tyrosine-protein kinase SYK 0.275 0.114
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.026
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.077
GAB2 N/A 0.251 0.026
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.036
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.251 0.032
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.026
WASPIP N/A 0.233 0.029
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.233 0.032
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.114
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.046
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.086
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.139
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.078
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.233
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.114
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.233 0.032
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.038
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.225 0.063
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.114
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.069
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.033
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.029
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.051
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.210 0.091
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.096
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.210
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.062
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.096
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.075
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.032
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.0425
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.063
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.188 0.038
CXorf9 N/A 0.188 0.086
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.032
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.078
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.233
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.139
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.233
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.086
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.032
RPS6KB1 N/A 0.188 0.188
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.114
FNBP1 N/A 0.188 0.046
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.029
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.038
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.171 0.029
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.225
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.171 0.114
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.028
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.028
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.083
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.028
PSCD2 N/A 0.165 0.028
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.083
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.028
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.028
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.083
NF2 NF2, SCH: Merlin 0.165 0.028
MAP2K5 N/A 0.165 0.083
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.028
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.155
HD HD, IT15: Huntingtin 0.155 0.070
ARFGAP1 N/A 0.155 0.027
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.127
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.155 0.077
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.077
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.153 0.100
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.152 0.062
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.077
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.026
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 0.077
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.075
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.025
CCNT2 CCNT2: Cyclin-T2 0.148 0.366
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.025
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.025
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.075
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.025
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.025
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.075
STAT3 0.148 0.025
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.075
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 2.13
ELMO1 N/A 0.148 0.025
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.025
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.025
ARHGEF7 N/A 0.148 0.025
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.046
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.038
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.063
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.188
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.139 0.385
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.111
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.114
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.188
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.188
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.114
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.139
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.056
ATM ATM: Serine-protein kinase ATM 0.139 0.086
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.372
CD2AP CD2AP: CD2-associated protein 0.139 0.063
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 0.188
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.139
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.038
RDX RDX: Radixin 0.136 0.046
CCNB1 Cyclin B1 0.136 0.040
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.049
STMN1 STMN1, LAP18, OP18: Stathmin 0.136 0.046
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.0425
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.225
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.129 0.032
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.063
RB1 RB1: Retinoblastoma-associated protein 0.127 0.0446
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.127
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.077
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.032
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.077
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.127
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.210
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.127 0.260
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.127 0.057
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.100
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.0425
HSPCB 0.119 3.01
RASGEF1A RASGEF1A: Ras-GEF domain-containing family member 1A 0.119 0.064
RASGEF1C N/A 0.119 0.064
NRAS NRAS, HRAS1: GTPase NRas precursor 0.118 0.046
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.046
PPP1R8 N/A 0.118 0.040
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.118 0.040
CDC37 CDC37: Hsp90 co-chaperone Cdc37 0.116 1.49
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.139
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.822
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.114 0.063
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.032
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.114 0.029
CDK5 CDK5: Cell division protein kinase 5 0.114 0.114
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.069
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.114
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.069
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.056
RPS10 RPS10: 40S ribosomal protein S10 0.114 0.139
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.114
THOC1 THOC1, HPR1: THO complex subunit 1 0.114 0.385
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.111 0.032
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.111 0.069
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.111 0.069
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.110 0.056
BMX N/A 0.110 0.049
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.109
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.026
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.098 0.062
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.098 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.098
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.097 0.086
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.056
SP100 N/A 0.0971 0.027
PTMA N/A 0.0971 0.074
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.0971 0.027
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.0446
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.096 0.253
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.032
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.0425
CIITA CIITA, MHC2TA: MHC class II transactivator 0.096 0.096
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.416
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.191
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.062
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.075
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.077
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.091 0.126
PTPRZ1 N/A 0.090 0.090
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.088 0.044
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.087
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.0425
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.074
IFI16 N/A 0.087 0.027
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.087 0.066
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.032
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.233
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.086
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.086 0.040
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.069
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.049
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.188
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.139
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.086
CTPS CTPS: CTP synthase 1 0.086 0.078
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.056
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.069
NPM1 NPM1, NPM: Nucleophosmin 0.086 0.032
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 0.056
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.086 0.063
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.086 2.18
TP53 TP53, P53: Cellular tumor antigen p53 0.086 0.111
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.083
MAPKAPK5 N/A 0.083 0.083
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.028
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.083
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.083
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.083
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.083
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.083
MAPK15 N/A 0.083 0.083
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.083
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.083
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.083
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.083
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.083
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.083
RUVBL1 RUVBL1, NMP238, TIP49, TIP49A: RuvB-like 1 0.082 0.132
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.078 0.044
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.046
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.040
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.078 0.063
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.078 0.032
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.046
LCP1 LCP1, PLS2: Plastin-2 0.078 0.114
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.078 0.063
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.063
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.078
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.038
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.078 24.50
HNRPK N/A 0.078 0.078
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.372
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.063
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.046
UBE4A N/A 0.078 0.078
KLHDC4 N/A 0.078 0.063
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 0.046
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.096
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.127
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.062
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.077
PRKAA1 N/A 0.077 0.077
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.077
STK16 N/A 0.077 0.077
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.077 0.0425
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.075 0.100
FADD FADD, MORT1: Protein FADD 0.075 0.075
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.075
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.075
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.075
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.075
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.075
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.075
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.075
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.075
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.075
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.044
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.044
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.075
GIT2 N/A 0.075 0.025
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.075
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.075
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.075
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.075
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.025
CNN2 CNN2: Calponin-2 0.075 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.075
SNX3 N/A 0.075 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.075
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.075
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.044
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.075
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.075
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.075
TSC2 TSC2, TSC4: Tuberin 0.075 0.025
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.075
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.075
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.0727
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.071 0.032
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.071 0.032
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.071 0.078
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.071 0.078
MCM3 MCM3: DNA replication licensing factor MCM3 0.071 0.040
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.040
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.071 0.066
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.027
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.087
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.087
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.070 0.036
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.070 0.0446
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.026
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.036
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.070 0.036
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.070 0.027
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.144
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.070 0.027
KIAA0853 N/A 0.070 0.0446
ABCF1 N/A 0.070 0.070
CASP8 N/A 0.070 0.026
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.070 0.074
TOP2B N/A 0.070 0.0446
IFI35 N/A 0.070 0.032
MARK2 N/A 0.070 0.026
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.070 0.053
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.069 0.063
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.114
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.049
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 0.069 0.051
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.056
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.069 0.044
VDR VDR, NR1I1: Vitamin D3 receptor 0.069 0.033
CDK6 CDK6: Cell division protein kinase 6 0.069 0.086
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.188
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.056
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.069 0.033
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.086
CDC20 CDC20: Cell division cycle protein 20 homolog 0.069 0.040
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.049
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.029
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.188
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.069 0.049
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.069
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.049
CDK4 CDK4: Cell division protein kinase 4 0.069 0.188
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.067 0.033
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.073
TIAL1 TIAL1: Nucleolysin TIAR 0.063 0.040
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.063 0.063
FRG1 FRG1: Protein FRG1 0.063 0.078
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.063 0.046
PTPN11 N/A 0.063 0.129
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.063 0.032
GSK3B N/A 0.063 0.046
COPA COPA: Coatomer subunit alpha 0.063 0.046
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.063 0.066
ACTG1 ACTB: Actin, cytoplasmic 1 0.063 2.47
MAD1L1 MAD1L1, MAD1, TXBP181: Mitotic spindle assembly checkpoint protein MAD1 0.063 0.029
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.063 0.086
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.063 0.763
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.046
NUP153 N/A 0.063 3.51
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.063 0.461
CKAP1 TBCB, CG22, CKAP1: Tubulin folding cofactor B 0.063 0.038
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.063 0.063
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.063 0.129
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.063 0.038
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.078
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.063
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.063 0.066
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.063 0.040
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.063 0.063
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.063 0.032
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.063 0.372
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.188
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.063 0.066
CUL5 CUL5, VACM1: Cullin-5 0.063 0.040
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.063 3.51
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.063 0.066
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.063 0.040
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.063 0.066
ARHGDIB ARHGDIB, GDIA2, GDID4, RAP1GN1: Rho GDP-dissociation inhibitor 2 0.063 0.038
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.046
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.063 0.069
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.046
EXOC2 N/A 0.063 0.038
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.063 0.066
EP300 N/A 0.063 0.032
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.063 0.040
PPARBP N/A 0.063 0.078
YY1 YY1: Transcriptional repressor protein YY1 0.063 0.040
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.188
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.063 0.066
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.063 0.066
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.063 0.032
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.063 0.032
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.063 0.032
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.063 0.040
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.063 0.040
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.063 0.139
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.062 0.062
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.127
SPTAN1 N/A 0.062 0.062
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.0453
CHAT CHAT: Choline O-acetyltransferase 0.062 0.098
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.064
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.058 0.065
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.057 0.081
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.057 0.032
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.056 0.046
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.056 0.035
WEE1 WEE1: Wee1-like protein kinase 0.056 0.139
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.056 0.056
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.056 0.114
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.056
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.188
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.056 0.086
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.056 0.033
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.049
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.114
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 1.58
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.056
STAM2 STAM2: Signal transducing adapter molecule 2 0.056 0.029
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.056 0.029
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.055 0.033
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.055
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.055 0.0453
TP73 TP73, P73: Tumor protein p73 0.055 0.037
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.054 0.066
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.054 0.788
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.032
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.026
SRPR SRPR: Uncharacterized protein SRPR 0.052 0.0425
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.052 0.032
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.052 0.416
FUBP1 N/A 0.052 0.210
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.052 0.026
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.052 0.0446
DNM2 N/A 0.052 0.032
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.052 0.036
CHUK N/A 0.052 0.087
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.032
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.052 0.036
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.052 0.027
SET SET: Protein SET 0.052 0.036
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.144
MVP MVP, LRP: Major vault protein 0.052 0.062
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.052 0.0446
LIMS1 N/A 0.052 0.052
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.052 0.036
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.032
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.052 0.074
RBM14 RBM14, SIP: RNA-binding protein 14 0.052 0.0446
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.070
API5 N/A 0.052 0.087
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.052 0.036
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.260
AHNAK AHNAK: AHNAK protein 0.052 0.026
DDX21 DDX21: Nucleolar RNA helicase 2 0.052 0.0446
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.052 0.027
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.052 0.036
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.051 0.033
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.050 0.026
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.040
CDKL5 N/A 0.049 0.044
PGR PGR, NR3C3: Progesterone receptor 0.049 0.032
DAPK2 DAPK2: Death-associated protein kinase 2 0.049 0.049
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.109
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.04
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.049 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.049 0.109
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.049 0.049
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.049 0.109
EDA N/A 0.049 0.049
PPARG CREB3L2-PPARgamma 0.049 0.029
DYRK3 N/A 0.049 0.069
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 1.58
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.048 0.036
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.048 0.070
MKI67 MKI67: Antigen KI-67 0.048 0.036
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.026
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.047 0.683
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.047 0.025
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.025
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.046 1.71
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.275
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.046 0.063
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.046
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.129
SP3 SP3: Transcription factor Sp3 0.046 0.032
QARS QARS: Glutaminyl-tRNA synthetase 0.046 0.372
HDAC3 HDAC3: Histone deacetylase 3 0.046 0.040
CDC23 CDC23: Cell division cycle protein 23 homolog 0.046 0.461
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.046 0.066
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.276
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.046 0.040
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.046 0.038
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.046 0.063
TBCE TBCE: Tubulin-specific chaperone E 0.046 0.188
SSB SSB: Lupus La protein 0.046 0.066
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.046 0.040
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.046 0.276
YARS YARS: Tyrosyl-tRNA synthetase, cytoplasmic 0.046 0.245
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.046 0.040
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.046 0.066
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.046 0.046
DLG1 N/A 0.046 0.046
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.046 0.066
BRPF1 BRPF1, BR140: Peregrin 0.046 0.029
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.046 1.62
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.046 0.046
WARS WARS, IFI53, WRS: Tryptophanyl-tRNA synthetase, cytoplasmic 0.046 0.136
NAPG NAPG, SNAPG: Gamma-soluble NSF attachment protein 0.046 0.275
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.029
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.046 0.046
XPO1 XPO1, CRM1: Exportin-1 0.046 0.129
FLII FLII, FLIL: Protein flightless-1 homolog 0.046 0.086
PREP PREP, PEP: Prolyl endopeptidase 0.046 0.038
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.046 0.040
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.046
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.046 1.26
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.038
COPE COPE: Coatomer subunit epsilon 0.046 0.225
LPXN LPXN, LDLP: Leupaxin 0.046 0.038
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.763
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.046 0.141
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.046 0.032
SAPS3 N/A 0.046 0.046
CBX3 CBX3: Chromobox protein homolog 3 0.046 0.066
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.086
PPIG PPIG: Peptidyl-prolyl cis-trans isomerase G 0.046 0.372
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.046 0.503
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.046 0.372
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.046 0.227
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.046 0.063
EPOR EPOR: Erythropoietin receptor precursor 0.0453 0.202
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.0453 0.032
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.0446 0.036
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 0.049
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.056
MYO3A MYO3A: Myosin IIIA 0.044 0.044
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.044
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.044 0.044
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.044
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.044
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.044 0.033
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.044
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.043 0.029
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.043 0.032
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.043 0.032
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.043 1.26
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.043 0.029
SREBF2 N/A 0.0425 0.027
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.0425 0.0425
DNMT1 DNMT1, AIM, DNMT: DNA 0.0425 0.036
TCOF1 N/A 0.0425 0.036
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.026
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.0425 0.036
VAV2 VAV2, RP11-153P4.1-003: Vav 2 oncogene 0.0425 0.052
GNB2L1 Lung cancer oncogene 7 0.0425 0.027
DAPP1 N/A 0.0425 0.032
MPG N/A 0.0425 0.032
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.0425 0.062
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.0425 0.036
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.0425 0.027
XRCC1 XRCC1: DNA-repair protein XRCC1 0.0425 0.027
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0425 0.027
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0425 0.052
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.041 0.041
KIT KIT: Mast/stem cell growth factor receptor precursor 0.041 0.067
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.040 0.033
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.050
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.040
RAB5A RAB5A, RAB5: Ras-related protein Rab-5A 0.039 0.232
GFAP GFAP: Glial fibrillary acidic protein 0.039 0.026
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.038 1.32
TPT1 TPT1: Translationally-controlled tumor protein 0.038 0.038
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.038 0.078
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.038 0.046
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.046
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.038 0.032
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.038 0.032
HDAC2 HDAC2: Histone deacetylase 2 0.038 0.066
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.038 0.066
RPL8 RPL8: 60S ribosomal protein L8 0.038 0.046
COPB2 COPB2: Coatomer subunit beta' 0.038 1.71
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.038 0.046
LDHB LDHB: L-lactate dehydrogenase B chain 0.038 0.078
GMFB GMFB: Glia maturation factor beta 0.038 0.046
SNRPC SNRPC: U1 small nuclear ribonucleoprotein C 0.038 0.040
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 0.038 0.038
PHF10 N/A 0.038 0.032
RP2 RP2: Protein XRP2 0.038 0.038
EIF2S2 EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2 0.038 0.032
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.038 0.225
APC N/A 0.038 0.029
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.038 0.032
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.038 0.046
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.038 0.032
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.038 3.35
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.038 0.078
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.078
DYNC1I2 N/A 0.038 0.046
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.038 0.038
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.078
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.038 0.063
CAT CAT: Catalase 0.038 0.063
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.038 0.276
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.066
CCT8 CCT8: Uncharacterized protein CCT8 0.038 4.15
CFL1 CFL1, CFL: Cofilin-1 0.038 0.029
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.038 0.032
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.078
CHP CHP: Calcium-binding protein p22 0.038 0.069
NOL1 N/A 0.038 0.032
MDN1 MDN1, KIAA0301: Midasin 0.038 0.063
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.038 0.040
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.038 0.171
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.046
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.038 0.040
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.038 0.063
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.038
HDGF HDGF, HMG1L2: Hepatoma-derived growth factor 0.038 0.040
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.038 0.046
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.037 0.032
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.037 0.072
GHR GHR: Growth hormone receptor precursor 0.037 0.126
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.037 0.100
KIAA0372 TTC37, KIAA0372: Tetratricopeptide repeat protein 37 0.036 3.20
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.036 0.057
CRLF3 N/A 0.036 0.166
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.036 0.027
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.036 0.0446
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.035 0.273
PDK1 PDK1: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precu 0.035 0.046
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.0688
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.029
PRLR PRLR: Prolactin receptor precursor 0.033 0.065
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.033 0.072
ITGB4 N/A 0.032 0.081
F3 F3: Tissue factor precursor 0.032 0.081
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.032 0.030
IL9R IL9R: Interleukin-9 receptor precursor 0.032 0.072
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.032 0.030
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.096
CP110 N/A 0.032 0.070
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.062
MAP2K5 N/A 0.032 0.026
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.032 0.027
UBAP2 N/A 0.032 0.070
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.032 0.026
IPO7 IPO7: Uncharacterized protein IPO7 0.032 0.070
COIL COIL, CLN80: Coilin 0.032 0.027
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.032 0.036
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.032 0.027
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.032 0.070
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.032 0.032
TPR TPR: Nucleoprotein TPR 0.032 0.040
MAN2A1 MAN2A1, MANA2: Alpha-mannosidase 2 0.032 0.032
VDP DKFZp451D234: Putative uncharacterized protein DKFZp451D234 0.032 0.032
SORL1 SORL1: Sortilin-related receptor precursor 0.032 0.113
RYR2 RYR2: Ryanodine receptor 2 0.031 0.025
RRAS RRAS: Ras-related protein R-Ras precursor 0.0308 0.423
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.029 0.026
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.029 0.029
NEO1 NEO1, NGN: Neogenin precursor 0.029 0.058
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.029 0.032
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.029
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.029 0.033
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.029 0.038
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 0.046
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.029 0.032
AHCYL1 AHCYL1, DCAL, XPVKONA: Putative adenosylhomocysteinase 2 0.029 0.029
PMM1 PMM1, PMMH22: Phosphomannomutase 1 0.029 0.038
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.038
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.029 0.063
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.029 0.029
MSH6 MSH6, GTBP: DNA mismatch repair protein MSH6 0.029 0.040
MCM4 MCM4, CDC21: DNA replication licensing factor MCM4 0.029 0.040
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.029 0.049
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.032
FKBP8 DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment) 0.029 0.136
MYBL2 MYBL2, BMYB: Myb-related protein B 0.029 0.032
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.029 0.040
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.029 0.225
UNG N/A 0.029 0.040
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.029 0.032
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.029 0.063
THOP1 THOP1: Thimet oligopeptidase 0.029 0.063
PRDX6 PRDX6, AOP2, KIAA0106: Peroxiredoxin-6 0.029 0.046
POLA2 POLA2: DNA polymerase subunit alpha B 0.029 2.12
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.029 0.556
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.029 0.040
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.038
DPYSL2 DPYSL2, CRMP2: Dihydropyrimidinase-related protein 2 0.029 0.029
RRM2 RRM2, RR2: Ribonucleoside-diphosphate reductase subunit M2 0.029 0.078
PCNA PCNA: Proliferating cell nuclear antigen 0.029 0.066
SYMPK SYMPK, SPK: Symplekin 0.029 0.029
LIG1 LIG1: DNA ligase 1 0.029 0.040
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.029 2.02
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.029 0.046
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.029 0.038
AIP AIP, XAP2: AH receptor-interacting protein 0.029 0.111
DCP1A DCP1A, SMIF: mRNA-decapping enzyme 1A 0.029 0.029
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.225
H2AFX H2AFX, H2AX: Histone H2A.x 0.029 0.040
GPI GPI: Glucose-6-phosphate isomerase 0.029 0.038
PKP4 PKP4: Plakophilin-4 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
CACNB2 N/A 0.028 0.028
C20orf18 N/A 0.028 0.049
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.165
PTPN7 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.028
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.083
AXIN1 0.028 0.028
MATK 0.028 0.028
UHRF1 0.028 0.049
PHLDB2 N/A 0.028 0.028
CDC42 N/A 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.083
PPEF1 N/A 0.028 0.083
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.028
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.165
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
LNX1 N/A 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
C9orf88 N/A 0.028 0.028
NCF4 N/A 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.028
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
CD69 CD69: Early activation antigen CD69 0.027 0.057
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.026 0.026
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.026 0.065
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.026 0.058
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.052
ESPL1 N/A 0.026 0.052
TRRAP N/A 0.026 0.032
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.0425
AFAP AFAP1, AFAP: Actin filament-associated protein 1 0.026 0.026
CENPA CENPA: Histone H3-like centromeric protein A 0.026 0.027
PHB2 PHB2, BAP, REA: Prohibitin-2 0.026 0.0425
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 0.062
DBN1 DBN1, D0S117E: Drebrin 0.026 0.026
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.026 0.070
EPN1 N/A 0.026 0.026
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.026 0.062
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.062
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.026 0.027
KIF23 N/A 0.026 0.036
IREB2 IREB2: Iron-responsive element-binding protein 2 0.026 0.026
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.026 0.026
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.025 0.063
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.025
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
BCR N/A 0.025 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.025
GSN GSN: Gelsolin precursor 0.025 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.075
LMO6 LMO6: LIM domain only protein 6 0.025 0.025
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.025
RAD50 RAD50: DNA repair protein RAD50 0.025 0.025
SCRIB N/A 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.714
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.075
MYO18A 0.025 0.025
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.025
EPN2 N/A 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.075
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.044
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.075
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.075
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.683
PRKCB1 N/A 0.025 0.025
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 1.33
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
GRK6 N/A 0.025 0.025
CASP7 N/A 0.025 0.025
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
RAC1 N/A 0.025 0.025
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.025
NIPBL N/A 0.025 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.075
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
CAMKK1 N/A 0.025 0.025
DBNL N/A 0.025 0.025
CAMK2A N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 0.025
SVIL SVIL: Supervillin 0.025 0.025
2.15E-3
Total Score 3.42