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Evidence of Interaction Between MAPK1 and PRKCI

The interaction score between MAPK1 and PRKCI is 23.70.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between MAPK1 and PRKCI = 0.23

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 2.88E-3
Orthology
OrganismMAPK1 OrthologuePRKCI OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
worm P39745 1 Q19266 1
fly P40417 1 Q8MT38 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in MAPK1 and PRKCI:
Domains in MAPK1Domains in PRKCI
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR003527 MAP kinase
IPR008349 ERK1/2 MAP kinase
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site
IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding
IPR000961 Protein kinase C-terminal domain
IPR000270 Octicosapeptide/Phox/Bem1p
IPR012233 PKC_zeta.

The Chi square scores for co-occurrence of domains that are present in MAPK1 and PRKCI are listed below.

Domain 1Domain 2Chi Square
IPR000719 Protein kinase IPR000719 Protein kinase 30.6895
IPR008349 ERK1/2 MAP kinase IPR000961 Protein kinase C-terminal domain 28.9668
IPR011009 Protein kinase-like IPR011009 Protein kinase-like 26.2215
IPR003527 MAP kinase IPR008271 Serine/threonine protein kinase, active site 20.8159
IPR008349 ERK1/2 MAP kinase IPR008271 Serine/threonine protein kinase, active site 17.555
IPR008271 Serine/threonine protein kinase, active site IPR000270 Octicosapeptide/Phox/Bem1p 16.2948
IPR008271 Serine/threonine protein kinase, active site IPR000961 Protein kinase C-terminal domain 14.8145
IPR008349 ERK1/2 MAP kinase IPR002290 Serine/threonine protein kinase 13.3941
IPR003527 MAP kinase IPR000961 Protein kinase C-terminal domain 12.1226
IPR002290 Serine/threonine protein kinase IPR000270 Octicosapeptide/Phox/Bem1p 11.8528
IPR003527 MAP kinase IPR002290 Serine/threonine protein kinase 10.9612
IPR002290 Serine/threonine protein kinase IPR000961 Protein kinase C-terminal domain 9.78704
IPR002290 Serine/threonine protein kinase IPR008271 Serine/threonine protein kinase, active site 8.88805
IPR000719 Protein kinase IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 7.73524
IPR000719 Protein kinase IPR008271 Serine/threonine protein kinase, active site 6.25263
IPR000719 Protein kinase IPR000270 Octicosapeptide/Phox/Bem1p 6.11715
IPR008271 Serine/threonine protein kinase, active site IPR008271 Serine/threonine protein kinase, active site 5.82656
IPR008349 ERK1/2 MAP kinase IPR000719 Protein kinase 4.26499
IPR002290 Serine/threonine protein kinase IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 3.92759
IPR003527 MAP kinase IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 3.37462
IPR008271 Serine/threonine protein kinase, active site IPR012233 PKC_zeta. 3.35494
IPR000719 Protein kinase IPR011009 Protein kinase-like 2.94434
IPR011009 Protein kinase-like IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 2.89989
IPR003527 MAP kinase IPR000719 Protein kinase 2.81413
IPR002290 Serine/threonine protein kinase IPR011009 Protein kinase-like 2.72953
IPR008349 ERK1/2 MAP kinase IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 2.53982
IPR008271 Serine/threonine protein kinase, active site IPR002219 Protein kinase C, phorbol ester/diacylglycerol binding 2.42446
IPR011009 Protein kinase-like IPR008271 Serine/threonine protein kinase, active site 2.11823
IPR000719 Protein kinase IPR000961 Protein kinase C-terminal domain 1.70622
IPR002290 Serine/threonine protein kinase IPR012233 PKC_zeta. 1.12632
IPR000719 Protein kinase IPR002290 Serine/threonine protein kinase 0.986464
IPR011009 Protein kinase-like IPR000270 Octicosapeptide/Phox/Bem1p 0.712045
IPR000719 Protein kinase IPR012233 PKC_zeta. 0.659479
IPR002290 Serine/threonine protein kinase IPR002290 Serine/threonine protein kinase 0.532451
IPR011009 Protein kinase-like IPR000961 Protein kinase C-terminal domain 0.394121
IPR003527 MAP kinase IPR011009 Protein kinase-like 0.150555
IPR008349 ERK1/2 MAP kinase IPR011009 Protein kinase-like 0.0192176
IPR011009 Protein kinase-like IPR012233 PKC_zeta. 0.00498052

The background colour of the table refers to:

  • Blue Domain is only present in MAPK1
  • Yellow Domain is only present in PRKCI
  • Green Domain is present in both MAPK1 and PRKCI

 0.165
Post-translational Modifications

Protein: MAPK1

PTMResidueReference
Acetylation 2 PubMed, HPRD
Dephosphorylation 187 PubMed, HPRD
N-acetylalanine 1 HPRD
Phosphorylation 29 PubMed, HPRD
Phosphorylation 41 PubMed, HPRD
Phosphorylation 181 PubMed, HPRD
Phosphorylation 185 PubMed, HPRD
Phosphorylation 187 PubMed, HPRD
Phosphorylation 202 PubMed, HPRD
Phosphothreonine 184 PubMed, HPRD
Phosphotyrosine 186 HPRD

Protein: PRKCI

PTMResidueReference
Phosphorylation 256 PubMed, HPRD
Phosphorylation 271 PubMed, HPRD
Phosphorylation 325 PubMed, HPRD
Localisation

Protein: MAPK1

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: PRKCI

LocalisationReference
Nucleus HPRD
Endosome HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between MAPK1 and PRKCI that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between MAPK1 andPRKCI. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , MAPK1 has 1694 interactors and PRKCI has 1370 interactors of which there are 1067 common interactors.

Common InteractorName of Common InteractorScore for MAPK1-Interactor (?)Score for PRKCI-Interactor (?)
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 153.00 65.60
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 115.00 0.064
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 94.70 0.113
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 62.30 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 62.30 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 62.30 0.098
DUSP14 DUSP14, MKP6: Dual specificity protein phosphatase 14 46.80 0.035
DUSP10 DUSP10, MKP5: Dual specificity protein phosphatase 10 12.60 0.027
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 7.38 0.067
CDK2 CDK2: Cell division protein kinase 2 6.80 0.171
HSPD1 6.11 0.038
HSP90AA1 Hsp89-alpha-delta-N 3.95 0.114
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 3.35 0.046
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 2.17 0.171
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 2.02 0.139
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.975 0.081
PLEK PLEK, P47: Pleckstrin 0.515 0.100
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.461 0.111
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.461 0.171
CRKL CRKL: Crk-like protein 0.461 0.171
JAK1 0.461 0.136
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.461 0.136
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.461 0.136
MSN MSN: Moesin 0.461 0.136
VAV1 VAV1, VAV: Proto-oncogene vav 0.461 0.111
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.461 0.171
DUSP7 DUSP7, PYST2: Dual specificity protein phosphatase 7 0.440 0.036
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.416 0.123
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.416 0.037
ELF1 ELF1: ETS-related transcription factor Elf-1 0.416 0.057
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.416 0.081
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.385 0.171
STK10 STK10: Uncharacterized protein STK10 0.385 0.111
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.385 0.086
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.372 0.111
STAT6 STAT6: Signal transducer and activator of transcription 6 0.372 0.136
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.372 0.090
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.372 0.136
LYN LYN: Tyrosine-protein kinase Lyn 0.372 0.111
PSCD4 PSCD4, CYT4: Cytohesin-4 0.372 0.111
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.372 0.113
CSK CSK: Tyrosine-protein kinase CSK 0.372 0.136
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.372 0.136
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.372 0.225
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.372 0.275
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.372 53.10
JUND JUND: Transcription factor jun-D 0.372 0.033
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.372 0.171
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.372 0.111
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.372 0.111
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.372 0.090
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.344 0.046
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.307 0.126
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.307 0.123
ROCK1 ROCK1: Rho-associated protein kinase 1 0.307 0.191
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.307 0.123
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.307 0.109
VASP VASP: Vasodilator-stimulated phosphoprotein 0.307 0.109
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.275 0.225
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.275 0.171
DOK1 DOK1: Docking protein 1 0.275 0.136
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.275 0.136
JUNB JUNB: Transcription factor jun-B 0.275 0.033
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.275 0.073
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.275 0.136
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.275 0.097
HCK N/A 0.275 0.097
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.275 108.00
MAFG MAFG: Transcription factor MafG 0.275 0.041
ETS1 ETS1, EWSR2: Protein C-ets-1 0.275 0.041
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.275 0.033
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.275 0.275
SYK SYK: Tyrosine-protein kinase SYK 0.275 0.136
DUSP11 DUSP11, PIR1: RNA/RNP complex-1-interacting phosphatase 0.274 0.035
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.260 0.062
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.251 0.123
GAB2 N/A 0.251 0.123
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.251 0.202
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.251 0.109
BACH1 BACH1: Transcription regulator protein BACH1 0.251 0.037
IRS2 IRS2: Insulin receptor substrate 2 0.251 0.123
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.233 0.041
WASPIP N/A 0.233 0.056
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.233 0.0818
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.233 0.056
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.233 0.069
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.233 0.136
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.233 0.171
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.233 0.086
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.233 0.171
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.233 0.111
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.233 0.067
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.233 0.056
CCNH CCNH: Cyclin-H 0.225 0.113
JUN JUN: Transcription factor AP-1 0.225 0.033
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.225 0.372
SH3BP5 N/A 0.225 0.097
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.225 0.136
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.225 0.136
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.225 0.041
STAT4 STAT4: Signal transducer and activator of transcription 4 0.225 0.073
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.225 0.171
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.225 0.097
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.225 0.0818
SOS1 SOS1: Son of sevenless homolog 1 0.225 0.148
RASA3 RASA3: Ras GTPase-activating protein 3 0.225 0.111
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.225 0.051
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.210 0.077
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.210 0.191
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.210 0.062
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.210 0.152
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.208 0.034
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.192 0.057
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.307
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.191 0.152
STAT2 STAT2: Signal transducer and activator of transcription 2 0.191 0.081
GMIP GMIP: GEM-interacting protein 0.188 0.111
SEC24B SEC24B: Protein transport protein Sec24B 0.188 0.139
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.188 0.069
CXorf9 N/A 0.188 0.056
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.188 0.041
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.188 0.114
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.188 0.225
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.188 0.086
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.188 0.275
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.188 0.171
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.188 0.051
RPS6KB1 N/A 0.188 0.171
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.188 0.171
FNBP1 N/A 0.188 0.069
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.174 0.109
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.171 0.073
RIN1 RIN1: Ras and Rab interactor 1 0.171 0.136
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.171 0.051
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.171 0.171
NCK2 NCK2: Cytoplasmic protein NCK2 0.171 0.171
PSD TYL: TYL protein 0.171 0.136
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.171 0.171
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.225
LNK SH2B3, LNK: SH2B adapter protein 3 0.165 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.165
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.165 0.165
PSCD2 N/A 0.165 0.165
NSBP1 NSBP1: Nucleosome-binding protein 1 0.165 0.109
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.165 0.165
BID BID: BH3-interacting domain death agonist 0.165 0.049
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.165 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.165
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.165 0.049
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.165
MAP2K5 N/A 0.165 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.165
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.155 0.152
HD HD, IT15: Huntingtin 0.155 0.026
ARFGAP1 N/A 0.155 0.075
H1FX H1FX: Histone H1x 0.155 0.0453
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.155 0.191
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.155 0.062
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.155 0.123
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.153 0.037
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.152 0.152
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.152 0.251
SNCB SNCB: Beta-synuclein 0.152 0.123
ERF ERF: ETS domain-containing transcription factor ERF 0.152 0.057
GAB1 GAB1: GRB2-associated-binding protein 1 0.152 0.191
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.152 0.191
ETS2 ETS2: Protein C-ets-2 0.152 0.075
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.148 0.098
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.148 0.098
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.148 0.148
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.148 12.60
CREB1 CREB1: cAMP response element-binding protein 0.148 0.098
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.148
CCNT2 CCNT2: Cyclin-T2 0.148 0.098
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.148 0.098
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.148 0.148
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.148 0.148
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.148 0.148
STAT3 0.148 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
ELMO1 N/A 0.148 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.148
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.148
ARHGEF7 N/A 0.148 0.148
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.146 0.171
PPP2R5A PPP2R5A: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha 0.146 0.043
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.146 0.136
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.139 0.225
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.139 0.114
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.139 0.113
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.139 0.041
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.139 0.275
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.139 0.033
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.139 0.225
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.139 0.041
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.139 0.225
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.139 0.111
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.139 0.171
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.139 0.111
ATM ATM: Serine-protein kinase ATM 0.139 0.056
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.139
CD2AP CD2AP: CD2-associated protein 0.139 0.114
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.139 82.20
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.139 0.033
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.139 0.136
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.139 0.041
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.139 0.111
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.136 0.064
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.136 0.136
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.136 0.136
RDX RDX: Radixin 0.136 0.136
CCNB1 Cyclin B1 0.136 0.113
VIL2 N/A 0.136 0.111
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.136 0.097
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.136 0.111
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.136 0.029
STMN1 STMN1, LAP18, OP18: Stathmin 0.136 0.225
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.136 0.041
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.132 0.191
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.129 0.029
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.129 0.029
CENTA1 CENTA1: Centaurin-alpha 1 0.128 0.051
RB1 RB1: Retinoblastoma-associated protein 0.127 0.075
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.127 0.098
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.127 0.123
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.127 0.055
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.127 0.152
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.127 0.152
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.127 0.307
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.127 0.155
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.124 0.037
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.123 0.077
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.152
ERG ERG: Transcriptional regulator ERG 0.123 0.057
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.123 0.152
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.123 0.123
NRAS NRAS, HRAS1: GTPase NRas precursor 0.118 108.00
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.118 0.029
PPP1R8 N/A 0.118 0.054
CDC37 CDC37: Hsp90 co-chaperone Cdc37 0.116 0.053
PGAM1 PGAM1, PGAMA, CDABP0006: Phosphoglycerate mutase 1 0.114 0.114
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.114 0.225
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.114 0.029
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.114 0.136
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.114 0.136
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.114 0.139
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.114 0.067
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.114 0.086
CDK5 CDK5: Cell division protein kinase 5 0.114 0.171
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.114 0.136
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.114 0.114
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.114 0.136
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.114 0.111
RPS10 RPS10: 40S ribosomal protein S10 0.114 0.086
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.114 0.111
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.114 0.041
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.114 0.275
THOC1 THOC1, HPR1: THO complex subunit 1 0.114 0.086
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.113 0.0818
MYCBP2 MYCBP2, KIAA0916, PAM: Probable E3 ubiquitin-protein ligase MYCBP2 0.111 0.051
PLD2 PLD2: Phospholipase D2 0.111 0.171
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.111 0.097
APS SH2B2, APS: SH2B adapter protein 2 0.111 0.136
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.111 0.275
ELK1 ELK1: ETS domain-containing protein Elk-1 0.111 0.041
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.111 0.111
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.111 0.033
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 0.111 0.097
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.111 82.20
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.111 0.136
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.110 0.109
BMX N/A 0.110 0.098
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.109
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.251
MCF2 MCF2, DBL: Proto-oncogene DBL 0.109 0.123
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.109 0.098
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.109 0.126
HMGA2 HMGA2, HMGIC: High mobility group protein HMGI-C 0.109 0.126
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.109 0.166
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.099 0.088
IRS1 IRS1: Insulin receptor substrate 1 0.098 0.251
ETV1 ETV1, ER81: ETS translocation variant 1 0.098 0.072
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.098 0.191
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.098 0.109
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.098 0.098
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.098 0.109
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.098
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.097 0.111
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.097 0.090
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.097 0.171
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.097 0.111
PLD1 PLD1: Phospholipase D1 0.097 0.111
DAB1 DAB1: Disabled homolog 1 0.097 0.097
TST TST: Thiosulfate sulfurtransferase 0.097 0.088
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.097
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.097 0.097
PTMA N/A 0.0971 0.046
NBN NBN, NBS, NBS1, P95: Nibrin 0.0971 0.061
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.096 0.057
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.096 0.055
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.096 0.077
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.096 0.077
NFATC1 N/A 0.096 0.037
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.096 0.075
CIITA CIITA, MHC2TA: MHC class II transactivator 0.096 0.077
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.096 0.155
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.096 0.077
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.096 0.152
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.096 0.126
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.096 0.109
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.096 0.037
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.091 0.037
CD44 N/A 0.091 0.057
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.090 0.033
PTPRZ1 N/A 0.090 0.073
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.088 0.113
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.088 46.80
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.088 0.111
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.087 0.0425
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.039
MATR3 MATR3, KIAA0723: Matrin-3 0.087 0.027
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.087 0.041
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.086 0.225
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.086 0.171
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.086 0.136
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.086 0.097
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.086 0.225
CDK7 CDK7, MO15: Cell division protein kinase 7 0.086 0.275
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.086 0.225
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.086 0.051
RELA RELA, NFKB3: Transcription factor p65 0.086 0.041
CTPS CTPS: CTP synthase 1 0.086 0.114
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.086 0.056
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.086 0.136
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.086 0.111
CDK5R1 CDK5R1, CDK5R, NCK5A: Cyclin-dependent kinase 5 activator 1 precursor 0.086 0.041
NPM1 NPM1, NPM: Nucleophosmin 0.086 0.067
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.086 53.10
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.086 0.139
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.086 0.041
XPC XPC, XPCC: DNA-repair protein complementing XP-C cells 0.086 0.033
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.083 0.165
MAPKAPK5 N/A 0.083 0.165
AMPH AMPH, AMPH1: Amphiphysin 0.083 0.083
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.165
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.083 0.083
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.083 0.165
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.083 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.083 0.083
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.083 0.165
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.049
CASP8 CASP8, MCH5: Caspase-8 precursor 0.083 0.083
MAPK15 N/A 0.083 0.083
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.049
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.083 0.165
CASP9 CASP9, MCH6: Caspase-9 precursor 0.083 0.083
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.083 0.083
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.083 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.083 0.083
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.083 0.165
HMGN4 HMGN4, HMG17L3, NHC: High mobility group nucleosome-binding domain-containing pr 0.083 0.032
IRF3 IRF3: Interferon regulatory factor 3 0.080 0.037
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.078 0.111
YWHAZ YWHAZ: 14-3-3 protein zeta/delta 0.078 0.275
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.078 0.038
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.029
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.078 0.038
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.071
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.029
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.078 0.029
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.078 0.038
HNRPK N/A 0.078 0.029
KIAA1012 KIAA1012: Protein TRS85 homolog 0.078 0.029
USP47 USP47: Ubiquitin carboxyl-terminal hydrolase 47 0.078 0.038
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.078 0.029
UBE4A N/A 0.078 0.038
YWHAB YWHAB: 14-3-3 protein beta/alpha 0.078 0.171
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.077 0.123
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.077 0.049
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.077 0.152
MYB MYB: Myb proto-oncogene protein 0.077 0.057
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.077 0.152
PRKAA1 N/A 0.077 0.152
LIMK2 LIMK2: LIM domain kinase 2 0.077 0.152
STK16 N/A 0.077 0.191
TSPYL2 TSPYL2, CDA1, HRIHFB2216, DENTT, TSPX: Testis-specific Y-encoded-like protein 2 0.077 0.037
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.077 0.191
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.077 0.077
ATP2B1 N/A 0.075 0.0453
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.075 0.037
FADD FADD, MORT1: Protein FADD 0.075 0.057
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.148
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.075 0.044
CDC2 CDC2: Cell division control protein 2 homolog 0.075 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.148
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.075 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.075 0.165
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.075 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.075 0.148
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.075 0.148
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.098
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.075 0.098
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.075 0.148
GIT2 N/A 0.075 0.075
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.075 0.075
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.075 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.075 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.075 0.075
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.075 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.075 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.075 0.075
CNN2 CNN2: Calponin-2 0.075 0.083
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.075 0.148
SNX3 N/A 0.075 0.075
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.148
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.075 0.098
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.044
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.075 0.075
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.075 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.075 0.075
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.075 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.148
TSC2 TSC2, TSC4: Tuberin 0.075 0.075
RBL1 RBL1: Retinoblastoma-like protein 1 0.075 0.044
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.075 0.075
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.075 0.148
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.073 0.090
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.073 0.064
GABRR1 N/A 0.0727 0.072
CDC42 CDC42: Cell division control protein 42 homolog precursor 0.073 0.064
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.081
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.071 0.041
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.071 0.041
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.071 0.041
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.071 0.114
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.071 0.275
MCM3 MCM3: DNA replication licensing factor MCM3 0.071 0.041
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.071 0.041
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.070 0.052
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.026
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.070 0.123
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.127
GTF3C1 N/A 0.070 0.027
ABCF1 N/A 0.070 0.032
TOP2B N/A 0.070 0.036
IFI35 N/A 0.070 0.026
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.070 0.053
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.069 0.114
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.069 0.136
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.069 0.136
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.111
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.069 0.171
CDK6 CDK6: Cell division protein kinase 6 0.069 0.136
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.069 0.171
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.069 0.111
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.139
CDC20 CDC20: Cell division cycle protein 20 homolog 0.069 0.041
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.069 0.111
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.069 0.139
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.069 0.136
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.069 0.111
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.069 0.097
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.069 0.097
CDK4 CDK4: Cell division protein kinase 4 0.069 0.225
BCL2L1 BCL2L1, BCL2L, BCLX: Apoptosis regulator Bcl-X 0.0688 0.034
MCL1 MCL1: Induced myeloid leukemia cell differentiation protein Mcl-1 0.0688 0.034
PSMA1 PSMA1, PROS30, PSC2: Proteasome subunit alpha type-1 0.067 0.041
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 0.067 0.026
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.090
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.063 0.105
BCL2 BCL2: Apoptosis regulator Bcl-2 0.063 0.031
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.063 0.029
FRG1 FRG1: Protein FRG1 0.063 0.029
PTPN11 N/A 0.063 0.046
GSK3B N/A 0.063 0.038
COPA COPA: Coatomer subunit alpha 0.063 0.038
ACTG1 ACTB: Actin, cytoplasmic 1 0.063 0.029
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.063 0.046
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.063 0.029
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.063 0.046
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.063 0.046
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.063 0.038
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.063 0.046
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.225
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.063 0.046
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.063 0.114
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.038
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.063 0.029
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.063 0.046
PPARBP N/A 0.063 0.038
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.063 0.038
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.063 0.029
GRLF1 N/A 0.062 0.191
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.062 0.055
MDM4 MDM4, MDMX: Mdm4 protein 0.062 0.037
COBL N/A 0.062 0.062
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.062 0.152
SPTAN1 N/A 0.062 0.077
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.029
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.062 0.100
CHAT CHAT: Choline O-acetyltransferase 0.062 0.062
GTF2F2 N/A 0.060 0.027
VIM VIM: Vimentin 0.060 0.0453
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.060 0.032
PSMB1 PSMB1, PSC5: Proteasome subunit beta type-1 precursor 0.060 0.036
USP8 USP8, KIAA0055, UBPY: Ubiquitin carboxyl-terminal hydrolase 8 0.060 0.036
PSMA6 PSMA6, PROS27: Proteasome subunit alpha type-6 0.060 0.044
MTMR6 MTMR6: Myotubularin-related protein 6 0.060 0.044
CCNI CCNI: Cyclin-I 0.060 0.029
PSMA7 PSMA7: Proteasome subunit alpha type-7 0.060 0.036
NUP50 NUP50, NPAP60L, PRO1146: Nucleoporin 50 kDa 0.060 0.028
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.058 0.090
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.058 0.064
GLRA1 N/A 0.058 0.073
PFKFB2 PFKFB2: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.057 0.057
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.057 0.057
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.057 0.0453
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.057 0.037
HADHB HADHB, MSTP029: Trifunctional enzyme subunit beta, mitochondrial precursor 0.056 0.028
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.056 0.056
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.056 0.094
WEE1 WEE1: Wee1-like protein kinase 0.056 0.171
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.056 0.069
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.056 0.086
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.056 0.136
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.056 0.136
TERT TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase 0.056 0.032
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 0.056 0.086
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.056 0.111
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.056 0.171
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.056 0.171
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.056 0.171
STAM2 STAM2: Signal transducing adapter molecule 2 0.056 0.069
SALF GTF2A1L, ALF, GTF2A1LF: TFIIA-alpha and beta-like factor 0.056 0.037
NOS1 NOS1: Nitric-oxide synthase, brain 0.056 0.099
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.055 0.038
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.055 0.075
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.109
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.055 0.0453
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.054 0.033
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.054 0.029
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.054 0.041
EIF4EBP1 EIF4EBP1: Eukaryotic translation initiation factor 4E-binding protein 1 0.053 0.070
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.053 0.042
RAB4A N/A 0.052 0.109
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.052 0.049
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.032
SRPR SRPR: Uncharacterized protein SRPR 0.052 0.032
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.052 0.032
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.052 0.096
FUBP1 N/A 0.052 0.0425
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.052 0.055
DNM2 N/A 0.052 0.026
CHUK N/A 0.052 0.032
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.052 0.026
SET SET: Protein SET 0.052 0.027
YWHAQ YWHAQ: 14-3-3 protein theta 0.052 0.416
LIMS1 N/A 0.052 0.096
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.026
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.052 0.0425
API5 N/A 0.052 0.0425
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.052 0.032
AHNAK AHNAK: AHNAK protein 0.052 0.032
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.052 0.027
C9orf88 N/A 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.051 0.051
CRK CRK: Proto-oncogene C-crk 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
PPP1R1B PPP1R1B, DARPP32: Protein phosphatase 1 regulatory subunit 1B 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
CCNK 0.051 0.051
PSMB4 PSMB4: Proteasome subunit beta type-4 precursor 0.051 0.051
PRH1 PRH1, PRH2: Salivary acidic proline-rich phosphoprotein 1/2 precursor 0.051 0.051
PPP1R14C PPP1R14C, KEPI: Protein phosphatase 1 regulatory subunit 14C 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
GRB10 N/A 0.051 0.051
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.051
RAPH1 N/A 0.051 0.051
PTPRA N/A 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.051 0.045
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.051 0.090
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.051 0.029
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.050
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.050 0.056
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.050 0.088
NFIB N/A 0.049 0.075
CDKL5 N/A 0.049 0.098
KRT1 KRT1, KRTA: Keratin, type II cytoskeletal 1 0.049 0.049
DAPK2 DAPK2: Death-associated protein kinase 2 0.049 0.152
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.049 0.049
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.049
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.049 0.049
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.049 0.049
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.049 0.049
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.049 0.049
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.049 0.049
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.049 0.049
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.049 0.049
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.049 0.049
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.049 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.049 0.049
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.049 0.049
GTF2A1 GTF2A1, TF2A1: Transcription initiation factor IIA subunit 1 0.049 0.041
SORBS3 SORBS3, SCAM1: Vinexin 0.049 0.086
DYRK3 N/A 0.049 0.136
AQP1 AQP1, CHIP28: Aquaporin-1 0.049 0.050
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.049 0.029
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.049 0.136
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.049 0.029
AQP2 AQP2: Aquaporin-2 0.049 0.049
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.048 0.046
BIRC5 BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5 0.048 0.048
NEFL NEFL, NF68, NFL: Neurofilament light polypeptide 0.048 0.055
MKI67 MKI67: Antigen KI-67 0.048 0.046
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.048 0.060
BAD BAD, BBC6, BCL2L8: Bcl2 antagonist of cell death 0.047 0.0253
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.047 0.047
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.047 0.036
LMNA LMNA, LMN1: Lamin-A/C 0.047 0.044
RAB5B RAB5B: Ras-related protein Rab-5B 0.047 0.148
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.069
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.046 0.029
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.046 0.029
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.046 0.046
QARS QARS: Glutaminyl-tRNA synthetase 0.046 0.038
CDC23 CDC23: Cell division cycle protein 23 homolog 0.046 0.046
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.046 0.275
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.046 0.051
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.046 0.038
TBCE TBCE: Tubulin-specific chaperone E 0.046 0.063
HSPH1 HSPH1, HSP105, HSP110, KIAA0201: Heat shock protein 105 kDa 0.046 0.038
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.046 0.029
DLG1 N/A 0.046 0.046
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.046 0.029
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.046 0.029
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.035
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.046 0.029
XPO1 XPO1, CRM1: Exportin-1 0.046 0.046
FLII FLII, FLIL: Protein flightless-1 homolog 0.046 0.029
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.046 0.056
PREP PREP, PEP: Prolyl endopeptidase 0.046 0.046
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.029
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.046 0.038
COPE COPE: Coatomer subunit epsilon 0.046 0.086
LPXN LPXN, LDLP: Leupaxin 0.046 0.086
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.046 0.046
SAPS3 N/A 0.046 0.038
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.046 0.086
PPIG PPIG: Peptidyl-prolyl cis-trans isomerase G 0.046 0.029
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.046 0.046
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.046 0.038
CCR5 CCR5: CCR5 receptor (Fragment) 0.046 0.032
TH TH, TYH: Tyrosine 3-monooxygenase 0.046 0.046
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.046
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
PPP1R14A PPP1R14A, CPI17, PPP1INL: Protein phosphatase 1 regulatory subunit 14A 0.046 0.046
VAV2 VAV2: Uncharacterized protein VAV2 0.046 0.046
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.046 0.058
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.046 0.041
HMGCR HMGCR: 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.046 0.056
COASY COASY, PSEC0106: Bifunctional coenzyme A synthase 0.046 0.035
EPOR EPOR: Erythropoietin receptor precursor 0.0453 0.032
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.0453 0.032
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.045 0.041
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.045 0.045
CGA CGA: Glycoprotein hormones alpha chain precursor 0.045 0.051
TSHB TSHB: Thyrotropin subunit beta precursor 0.045 0.051
FSHB FSHB: Follitropin subunit beta precursor 0.045 0.051
LHB LHB: Lutropin subunit beta precursor 0.045 0.051
PSMB3 PSMB3: Proteasome subunit beta type-3 0.044 0.028
AAMP AAMP: Angio-associated migratory cell protein 0.044 0.029
PSMA4 PSMA4, PSC9: Proteasome subunit alpha type-4 0.044 0.044
MTMR1 MTMR1: Myotubularin-related protein 1 0.044 0.028
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.044 65.60
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.044 0.041
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.044 0.136
MYO3A MYO3A: Myosin IIIA 0.044 0.088
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.044 0.111
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.044 0.088
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.044 0.111
CNN3 CNN3: Calponin-3 0.044 0.062
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.044 0.136
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.044 0.086
CTTN CTTN, EMS1: Src substrate cortactin 0.044 0.096
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.044 0.049
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.044 0.044
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.044 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.044
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.044 0.044
AQP4 AQP4: Aquaporin-4 0.044 0.044
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.098
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.044 0.098
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.044
TXN TXN, TRDX, TRX, TRX1: Thioredoxin 0.043 0.139
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.043 0.027
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.043 0.054
FTH1 FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain 0.0425 0.026
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.032
DAPP1 N/A 0.0425 0.026
MPG N/A 0.0425 0.0425
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.0425 0.027
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.0425 0.027
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.0425 0.0425
PDE4A N/A 0.0425 0.026
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.042 0.053
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.041 0.067
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.041 0.071
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.037
INHA INHA: Inhibin alpha chain precursor 0.041 0.045
KRT8 KRT8, CYK8: Keratin, type II cytoskeletal 8 0.041 0.039
NDP NDP: Norrin precursor 0.041 0.041
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.041 0.045
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.041 0.051
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.041 0.051
GRM3 GRM3, GPRC1C, MGLUR3: Metabotropic glutamate receptor 3 precursor 0.041 0.073
KIT KIT: Mast/stem cell growth factor receptor precursor 0.041 0.067
GLRB GLRB: Glycine receptor subunit beta precursor 0.041 0.041
FGF9 FGF9: Glia-activating factor precursor 0.041 0.046
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.041 0.057
TBXA2R TBXA2R: Thromboxane A2 receptor 0.04 0.049
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.04 0.04
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.040 0.033
ITGB7 ITGB7: Integrin beta-7 precursor 0.040 0.033
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.040 0.099
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.040 0.097
RAC2 RAC2: Ras-related C3 botulinum toxin substrate 2 precursor 0.039 0.046
RAB8A RAB8A: RAB8A protein 0.039 0.036
RAB5A RAB5A, RAB5: Ras-related protein Rab-5A 0.039 0.058
NEF3 NEFM, NEF3, NFM: Neurofilament medium polypeptide 0.039 0.049
GFAP GFAP: Glial fibrillary acidic protein 0.039 0.049
TLN1 TLN1: Uncharacterized protein TLN1 0.038 0.069
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.038 0.029
G3BP G3BP1, G3BP: Ras GTPase-activating protein-binding protein 1 0.038 0.038
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.038 0.038
VCP VCP: Transitional endoplasmic reticulum ATPase 0.038 0.038
YEATS2 KIAA1197, YEATS2: YEATS domain-containing protein 2 0.038 0.032
HDAC2 HDAC2: Histone deacetylase 2 0.038 0.032
RPL8 RPL8: 60S ribosomal protein L8 0.038 0.029
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.038 0.029
LDHB LDHB: L-lactate dehydrogenase B chain 0.038 0.046
GMFB GMFB: Glia maturation factor beta 0.038 0.038
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.038 0.038
APC N/A 0.038 0.029
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.038 0.029
CCT4 CCT4, CCTD, SRB: T-complex protein 1 subunit delta 0.038 0.046
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.038 0.038
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.038
DYNC1I2 N/A 0.038 0.038
SENP6 SENP6, KIAA0797, FKSG6, SSP1, SUSP1: Sentrin-specific protease 6 0.038 0.038
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.038 0.038
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.038 0.029
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.038 0.046
CCT8 CCT8: Uncharacterized protein CCT8 0.038 0.038
CFL1 CFL1, CFL: Cofilin-1 0.038 0.029
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.038 0.046
MDN1 MDN1, KIAA0301: Midasin 0.038 0.038
STUB1 STUB1, CHIP, PP1131: STIP1 homology and U box-containing protein 1 0.038 0.029
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.038 0.063
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.038 0.038
EEF2 EEF2, EF2: Elongation factor 2 0.038 0.225
BAP1 BAP1, KIAA0272, hucep-6: Ubiquitin carboxyl-terminal hydrolase BAP1 0.038 0.029
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.037 0.032
RAP1GA1 N/A 0.037 0.0453
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.037 0.037
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.037 0.037
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.037 0.032
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.037 0.037
GHR GHR: Growth hormone receptor precursor 0.037 0.032
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.037 0.0453
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.037 0.037
PFKFB1 N/A 0.037 0.041
PDCL PDCL: Phosducin-like protein 0.036 0.053
PPP1R2 PPP1R2, IPP2: Protein phosphatase inhibitor 2 0.036 0.030
EIF4E EIF4E, EIF4EL1, EIF4F: Eukaryotic translation initiation factor 4E 0.036 0.036
KIAA0372 TTC37, KIAA0372: Tetratricopeptide repeat protein 37 0.036 0.060
PSMB2 PSMB2: Proteasome subunit beta type-2 0.036 0.036
PSMB6 PSMB6, LMPY: Proteasome subunit beta type-6 precursor 0.036 0.036
PTPN9 0.036 0.036
PRKD3 PRKD3, EPK2, PRKCN: Serine/threonine-protein kinase D3 0.036 0.036
CCND2 CCND2: G1/S-specific cyclin-D2 0.036 0.029
RHOG RHOG, ARHG: Rho-related GTP-binding protein RhoG precursor 0.0354 0.0416
TXNDC TXNDC1, TMX, PSEC0085, TXNDC, UNQ235/PRO268: Thioredoxin domain-containing prote 0.035 0.056
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.035 0.029
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.035 0.0308
PDK1 PDK1: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial precu 0.035 0.035
KRT20 KRT20: Keratin, type I cytoskeletal 20 0.034 0.0453
NEFH NEFH, KIAA0845, NFH: Neurofilament heavy polypeptide 0.034 0.055
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.034 0.034
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.0338 0.047
TPH1 N/A 0.0338 0.038
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.034 0.034
MAL2 MAL2: Protein MAL2 0.034 0.034
NOS2A NOS2A, NOS2: Nitric oxide synthase, inducible 0.034 0.030
XPNPEP1 N/A 0.033 0.0407
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.033 0.073
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.033 0.073
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.033 0.073
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.033 0.051
GRM1 GRM1, GPRC1A, MGLUR1: Metabotropic glutamate receptor 1 precursor 0.033 0.090
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.033 0.064
PRLR PRLR: Prolactin receptor precursor 0.033 0.029
RHO RHO, OPN2: Rhodopsin 0.033 0.065
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.033 0.0727
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.033 0.032
ITGB4 N/A 0.032 0.057
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.032 0.032
F3 F3: Tissue factor precursor 0.032 0.075
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.032 0.037
IL9R IL9R: Interleukin-9 receptor precursor 0.032 0.0453
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.032 0.057
CASR CASR, GPRC2A, PCAR1: Extracellular calcium-sensing receptor precursor 0.032 0.081
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.032 0.251
CP110 N/A 0.032 0.032
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.032 0.026
ZYX ZYX: Zyxin 0.032 0.062
MAP2K5 N/A 0.032 0.026
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.032 0.027
UBAP2 N/A 0.032 0.0425
YWHAH YWHAH, YWHA1: 14-3-3 protein eta 0.032 0.123
IPO7 IPO7: Uncharacterized protein IPO7 0.032 0.087
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.032 0.027
NME1 NME1, NDPKA, NM23: Nucleoside diphosphate kinase A 0.032 0.0425
NAT1 NAT1, AAC1: Arylamine N-acetyltransferase 1 0.032 0.026
RYR2 RYR2: Ryanodine receptor 2 0.031 0.031
KRT18 KRT18: Uncharacterized protein KRT18 0.031 0.0453
DES DES: Desmin 0.031 0.055
RRAS RRAS: Ras-related protein R-Ras precursor 0.0308 0.136
RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 0.0308 0.110
WSB2 WSB2: WD repeat and SOCS box-containing protein 2 0.0308 0.032
PPP1R14D PPP1R14D, GBPI: Protein phosphatase 1 regulatory subunit 14D 0.031 0.0273
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.030 0.030
PPP1R1A PPP1R1A, IPP1: Protein phosphatase 1 regulatory subunit 1A 0.030 0.030
GJA5 GJA5: Gap junction alpha-5 protein 0.030 0.030
PEBP1 PEBP1, PBP, PEBP: Phosphatidylethanolamine-binding protein 1 0.030 0.034
C1QBP C1QBP, GC1QBP, HABP1, SF2P32: Complement component 1 Q subcomponent-binding prot 0.030 0.030
OPRM1 OPRM1, MOR1: Mu-type opioid receptor 0.030 0.030
ABCB9 ABCB9, KIAA1520: ATP-binding cassette sub-family B member 9 precursor 0.030 0.030
METAP1 METAP1, KIAA0094: Methionine aminopeptidase 1 0.030 0.049
PA2G4 PA2G4, EBP1: Proliferation-associated protein 2G4 0.030 0.030
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.029 0.033
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.029 0.058
NEO1 NEO1, NGN: Neogenin precursor 0.029 0.041
EGF EGF: Pro-epidermal growth factor precursor 0.029 0.032
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.029 0.032
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.029 0.037
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.029 0.032
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.064
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.029 0.041
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.029
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.029 0.046
CASP3 CASP3, CPP32: Caspase-3 precursor 0.029 22.30
KIAA0690 N/A 0.029 0.029
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.029 0.038
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.029 0.038
GSTP1 GSTP1, FAEES3, GST3: Glutathione S-transferase P 0.029 0.046
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.029 0.041
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.029 0.029
KPNA2 KPNA2, RCH1, SRP1: Importin subunit alpha-2 0.029 0.038
THOP1 THOP1: Thimet oligopeptidase 0.029 0.029
PPP2CB PPP2CB: Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform 0.029 0.029
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.046
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.063
DPYSL2 DPYSL2, CRMP2: Dihydropyrimidinase-related protein 2 0.029 0.069
GAPD GAPDH, GAPD, CDABP0047, OK/SW-cl.12: Glyceraldehyde-3-phosphate dehydrogenase 0.029 0.046
IMPAD1 N/A 0.029 0.038
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.029 0.046
ENO1 ENO1, ENO1L1, MBPB1, MPB1: Alpha-enolase 0.029 0.046
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.029 0.038
GPI GPI: Glucose-6-phosphate isomerase 0.029 0.029
PKP4 PKP4: Plakophilin-4 0.028 0.028
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.028
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.165
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.083
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
SH2D3A SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A 0.028 0.028
AHSA2 AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236 0.028 0.028
CACNB2 N/A 0.028 0.028
C20orf18 N/A 0.028 0.049
DNAJC13 DNAJC13, KIAA0678, RME8: DnaJ homolog subfamily C member 13 0.028 0.028
PTPN7 N/A 0.028 0.028
STAP2 Uncharacterized protein ENSP00000317912 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.049
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.028 0.028
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.028 0.028
AXIN1 0.028 0.083
MATK 0.028 0.028
UHRF1 0.028 0.049
PHLDB2 N/A 0.028 0.028
CDC42 N/A 0.028 0.028
PDE5A PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase 0.028 0.028
S100A16 S100A16, AAG13: Protein S100-A16 0.028 0.028
PPEF1 N/A 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.165
ABLIM1 ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
NASP NASP: Nuclear autoantigenic sperm protein 0.028 0.028
SIVA SIVA1, SIVA: Apoptosis regulatory protein Siva 0.028 0.028
LNX1 N/A 0.028 0.028
SPAG6 SPAG6, PF16: Sperm-associated antigen 6 0.028 0.028
CASP14 CASP14: Caspase-14 precursor 0.028 0.028
C9orf88 N/A 0.028 0.028
NCF4 N/A 0.028 0.028
SLC9A3R2 SLC9A3R2: SLC9A3R2 protein (Fragment) 0.028 0.028
FASN FASN, FAS: Fatty acid synthase 0.028 0.083
CASP6 CASP6, MCH2: Caspase-6 precursor 0.028 0.028
KRAS N/A 0.0278 0.041
FOXL2 FOXL2: Forkhead box protein L2 0.028 0.033
RRAD RRAD, RAD: GTP-binding protein RAD 0.028 0.097
PRPH PRPH, NEF4, PRPH1: Peripherin 0.0277 0.049
CCNG2 CCNG2: Cyclin-G2 0.028 0.029
RANBP1 RANBP1: Ran-specific GTPase-activating protein 0.028 0.028
CCNG1 CCNG1, CCNG, CYCG1: Cyclin-G1 0.028 0.035
CCNC CCNC: Cyclin-C 0.028 0.047
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.027 0.029
WDR72 N/A 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
PTPN13 N/A 0.027 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.027 0.027
PSD3 N/A 0.027 0.027
ACP1 ACP1: Protein-tyrosine-phosphatase, isoform 3 0.027 0.027
OSBPL6 OSBPL6, ORP6: Oxysterol-binding protein-related protein 6 0.027 0.027
PLEKHA4 PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
DOK6 DOK6: Uncharacterized protein DOK6 0.027 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.027 0.027
FAM43A N/A 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
CADPS CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1 0.027 0.027
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
CDC25B CDC25B, CDC25HU2: M-phase inducer phosphatase 2 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
NOXA1 NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
OSBPL9 N/A 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
PSMB5 PSMB5, LMPX: Proteasome subunit beta type-5 precursor 0.027 0.027
ASB2 ASB2: Ankyrin repeat and SOCS box protein 2 0.027 0.027
ASB3 ASB3: ASB3 protein 0.027 0.027
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.027 0.027
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
CADPS2 CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2 0.027 0.027
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.027 0.037
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.0263 0.037
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.026 0.041
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.026 0.033
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.026 0.029
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.026 0.090
PDIA3 PDIA3, ERP57, ERP60, GRP58: Protein disulfide-isomerase A3 precursor 0.026 0.076
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.032
ESPL1 N/A 0.026 0.026
TRRAP N/A 0.026 0.0425
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.0425
AFAP AFAP1, AFAP: Actin filament-associated protein 1 0.026 0.032
PHB2 PHB2, BAP, REA: Prohibitin-2 0.026 0.032
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.026 0.062
DBN1 DBN1, D0S117E: Drebrin 0.026 0.070
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.026 0.0425
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.026 0.037
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.026 0.026
DCAMKL1 DCLK1, DCAMKL1, DCDC3A, KIAA0369: Serine/threonine-protein kinase DCLK1 0.026 0.026
RGS4 RGS4: Regulator of G-protein signaling 4 0.026 0.077
IREB2 IREB2: Iron-responsive element-binding protein 2 0.026 0.032
USP21 USP21, USP23: Ubiquitin carboxyl-terminal hydrolase 21 0.026 0.032
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.0253 0.059
SLC18A2 SLC18A2, SVMT, VMAT2: Synaptic vesicular amine transporter 0.0253 0.0253
PLA2G4A PLA2G4A, CPLA2, PLA2G4: Cytosolic phospholipase A2 0.0253 0.0253
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.025 0.063
IL18 IL18, IGIF, IL1F4: Interleukin-18 precursor 0.025 0.031
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.025 0.025
CHTF18 RUVBL, CHTF18: Protein CTF18 homolog. 0.025 0.025
PDE4B PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.025 0.148
WRNIP1 WRNIP1, WHIP: ATPase WRNIP1 0.025 0.028
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.148
BCR N/A 0.025 0.025
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.025 0.025
GSN GSN: Gelsolin precursor 0.025 0.025
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.025 0.025
LMO6 LMO6: LIM domain only protein 6 0.025 0.075
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.025 0.025
RAD50 RAD50: DNA repair protein RAD50 0.025 0.075
SCRIB N/A 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.047
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 0.025 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.025
NCOA5 NCOA5, KIAA1637: Nuclear receptor coactivator 5 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
MYO18A 0.025 0.148
COTL1 COTL1, CLP: Coactosin-like protein 0.025 0.025
EPN2 N/A 0.025 0.025
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.025 0.148
SH3PX3 SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3. 0.025 0.025
DPP8 DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8 0.025 0.025
G3BP2 G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.025 0.148
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.075
UBE2A UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A 0.025 0.025
SPAST SPAST, KIAA1083, SPG4: Spastin 0.025 0.025
ACTN4 ACTN4: Alpha-actinin-4 0.025 0.025
DCTN1 DCTN1: Dynactin subunit 1 0.025 0.025
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.025 0.044
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.044
RAB1B RAB1B: Ras-related protein Rab-1B 0.025 0.040
PRKCB1 N/A 0.025 0.025
HSPA8 HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
GRK6 N/A 0.025 0.025
CASP7 N/A 0.025 0.025
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.025 0.148
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
RAC1 N/A 0.025 0.025
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.025 0.025
NIPBL N/A 0.025 0.025
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.025 0.025
USP16 USP16: Ubiquitin carboxyl-terminal hydrolase 16 0.025 0.025
DCP1B DCP1B: mRNA-decapping enzyme 1B 0.025 0.025
CAMKK1 N/A 0.025 0.025
DBNL N/A 0.025 0.025
CAMK2A N/A 0.025 0.025
RSN CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1 0.025 0.025
CFL2 CFL2: Cofilin-2 0.025 0.025
SVIL SVIL: Supervillin 0.025 0.025
0.347
Total Score 23.70