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Evidence of Interaction Between SNRPG and REXO2

The interaction score between SNRPG and REXO2 is 13.70.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between SNRPG and REXO2 = 0.58

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 6.27E-3
Orthology
OrganismSNRPG OrthologueREXO2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YFL017W-A 1 YLR059C 1
worm Q9N4G9 1 Q17819 1
fly Q9VXE0 1 Q9VCI0 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains No domains were used in calculating likelihood of interaction 0.027
Post-translational Modifications

Protein: SNRPG

PTMResidueReference

Protein: REXO2

PTMResidueReference
Phosphotyrosine 122 HPRD
Phosphotyrosine 184 HPRD
Localisation

Protein: SNRPG

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: REXO2

LocalisationReference
Nucleus HPRD
Mitochondrion HPRD
Transitive Score

The common interactors between SNRPG and REXO2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between SNRPG andREXO2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , SNRPG has 256 interactors and REXO2 has 556 interactors of which there are 52 common interactors.

Common InteractorName of Common InteractorScore for SNRPG-Interactor (?)Score for REXO2-Interactor (?)
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 2.07E3 0.372
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 2.07E3 0.372
SNRPD2 SNRPD2, SNRPD1: Small nuclear ribonucleoprotein Sm D2 691.00 0.044
LSM5 LSM5: U6 snRNA-associated Sm-like protein LSm5 691.00 0.126
LSM4 LSM4: U6 snRNA-associated Sm-like protein LSm4 691.00 0.028
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 32.60 0.046
SNRPE SNRPE: Small nuclear ribonucleoprotein E 8.73 0.067
SNRPB SNRPB, COD, SNRPB1: Small nuclear ribonucleoprotein-associated proteins B and B' 2.91 0.050
LSM3 LSM3, MDS017: U6 snRNA-associated Sm-like protein LSm3 2.60 0.126
LSM7 LSM7: U6 snRNA-associated Sm-like protein LSm7 2.60 0.044
LSM8 LSM8: U6 snRNA-associated Sm-like protein LSm8 2.60 0.093
SNRPF SNRPF, PBSCF: Small nuclear ribonucleoprotein F 2.60 0.044
SF3A2 SF3A2, SAP62: Splicing factor 3A subunit 2 1.84 0.685
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 1.22 0.171
LSM6 LSM6: U6 snRNA-associated Sm-like protein LSm6 1.22 0.036
LSM1 LSM1, CASM: U6 snRNA-associated Sm-like protein LSm1 1.22 0.044
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.890 0.029
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.354 0.025
DDX21 DDX21: Nucleolar RNA helicase 2 0.293 0.052
CDC20 CDC20: Cell division cycle protein 20 homolog 0.263 0.063
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.263 0.046
GNB2L1 Lung cancer oncogene 7 0.137 0.0425
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.137 0.052
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.123 0.038
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.123 0.046
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.123 0.038
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.123 0.038
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.123 0.063
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.123 0.046
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.083 0.032
CORO1C CORO1C, CRNN4: Coronin-1C 0.074 0.029
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.074 0.038
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.074 0.038
COPA COPA: Coatomer subunit alpha 0.074 0.029
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.074 0.038
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.074 0.046
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.074 0.129
WDR1 N/A 0.067 0.032
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.060 0.046
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.060 0.038
EXOSC8 EXOSC8, OIP2, RRP43: Exosome complex exonuclease RRP43 0.057 0.065
EXOSC7 EXOSC7, KIAA0116, RRP42: Exosome complex exonuclease RRP42 0.051 0.029
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.044 0.029
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.044 0.029
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.044 0.038
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.044 0.063
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.044 0.078
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.044 0.078
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.044 0.063
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.036 0.038
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.027 0.028
WDR54 N/A 0.027 0.028
0.572
Total Score 13.70