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Evidence of Interaction Between SNRPG and PRMT5

The interaction score between SNRPG and PRMT5 is 5.63.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between SNRPG and PRMT5 = 0.85

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 0.027
Orthology
OrganismSNRPG OrthologuePRMT5 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YFL017W-A 1 YBR133C 1
worm Q9N4G9 1 P46580 1
fly Q9VXE0 1 Q9U6Y9 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains No domains were used in calculating likelihood of interaction N/A
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation No localisation data was used in calculating likelihood of interaction
Transitive Score

The common interactors between SNRPG and PRMT5 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between SNRPG andPRMT5. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , SNRPG has 256 interactors and PRMT5 has 134 interactors of which there are 22 common interactors.

Common InteractorName of Common InteractorScore for SNRPG-Interactor (?)Score for PRMT5-Interactor (?)
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 2.07E3 0.0479
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 2.07E3 0.0479
SNRPE SNRPE: Small nuclear ribonucleoprotein E 8.73 0.027
SNRPB SNRPB, COD, SNRPB1: Small nuclear ribonucleoprotein-associated proteins B and B' 2.91 0.027
PRPF6 PRPF6, C20orf14: Pre-mRNA-processing factor 6 0.890 1.84
DDX21 DDX21: Nucleolar RNA helicase 2 0.293 0.025
DHX15 DHX15, DBP1, DDX15: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase 0.293 0.027
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.137 0.025
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.083 0.025
SERBP1 N/A 0.082 0.027
PTGES3 PTGES3, P23, TEBP: Prostaglandin E synthase 3 0.082 0.053
PA2G4 PA2G4, EBP1: Proliferation-associated protein 2G4 0.0739 0.0479
HNRPC N/A 0.049 0.027
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.044 0.0479
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.044 0.0479
HSPC185 CGI-117, HSPC111: UPF0384 protein CGI-117 0.027 0.027
GMNN GMNN: Geminin 0.027 0.025
ILF2 ILF2, NF45, PRO3063: Interleukin enhancer-binding factor 2 0.027 0.027
NOLC1 NOLC1, KIAA0035: Nucleolar phosphoprotein p130 0.027 0.053
BUB3 N/A 0.027 0.027
XTP3TPA XTP3TPA, CDA03: XTP3-transactivated gene A protein 0.027 0.027
KARS KARS, KIAA0070: Lysyl-tRNA synthetase 0.027 0.027
0.572
Total Score 5.63