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Evidence of Interaction Between SNRPG and SF3B3

The interaction score between SNRPG and SF3B3 is 3.36.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between SNRPG and SF3B3 = 0.82

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.027
Orthology
OrganismSNRPG OrthologueSF3B3 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YFL017W-A 1 YML049C 1
  • Other
  • AffinityCaptureMS

Get References From PubMed

worm Q9N4G9 1 O44985 1
fly Q9VXE0 1 Q9W0M7 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.593
Domains No domains were used in calculating likelihood of interaction 1.48E-3
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation

Protein: SNRPG

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: SF3B3

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between SNRPG and SF3B3 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between SNRPG andSF3B3. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , SNRPG has 256 interactors and SF3B3 has 189 interactors of which there are 120 common interactors.

Common InteractorName of Common InteractorScore for SNRPG-Interactor (?)Score for SF3B3-Interactor (?)
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 2.07E3 3.89
LSM4 LSM4: U6 snRNA-associated Sm-like protein LSm4 691.00 1.82
PRPF4 PRPF4, PRP4: U4/U6 small nuclear ribonucleoprotein Prp4 69.60 0.123
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 32.60 1.82
PRP19 PRPF19, NMP200, PRP19, SNEV: Pre-mRNA-processing factor 19 25.60 25.60
SNRPA1 SNRPA1: U2 small nuclear ribonucleoprotein A' 3.89 3.89
SNRPF SNRPF, PBSCF: Small nuclear ribonucleoprotein F 2.60 1.82
SF3A2 SF3A2, SAP62: Splicing factor 3A subunit 2 1.84 1.49
SF3A3 SF3A3, SAP61: Splicing factor 3A subunit 3 1.84 3.05
PRPF8 PRPF8, PRPC8: Pre-mRNA-processing-splicing factor 8 1.84 1.84
TXNL4A TXNL4A, DIM1, TXNL4: Thioredoxin-like protein 4A 1.82 0.038
LSM6 LSM6: U6 snRNA-associated Sm-like protein LSm6 1.22 1.82
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.890 0.890
NUP37 NUP37: Nucleoporin Nup37 0.789 0.123
SF3B2 SF3B2, SAP145: Splicing factor 3B subunit 2 0.593 0.593
LUC7L N/A 0.593 0.593
SF3A1 SF3A1, SAP114: Splicing factor 3 subunit 1 0.412 0.249
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.354 0.354
SNRPEL1 RP11-390F4.1-001: Small nuclear ribonucleoprotein polypeptide E-like protein 1. 0.354 0.354
CROP CROP, CREAP1, O48: Cisplatin resistance-associated overexpressed protein 0.300 0.371
DHX15 DHX15, DBP1, DDX15: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase 0.293 0.059
RBBP4 RBBP4, RBAP48: Histone-binding protein RBBP4 0.263 0.123
NUP43 N/A 0.263 0.263
CDC20 CDC20: Cell division cycle protein 20 homolog 0.263 0.074
BOP1 BOP1, KIAA0124: Ribosome biogenesis protein BOP1 0.263 0.123
SEC13L1 SEC13, D3S1231E, SEC13L1, SEC13R: Protein SEC13 homolog 0.137 0.083
WDR41 N/A 0.137 0.137
GNB2L1 Lung cancer oncogene 7 0.137 0.083
GTF3C2 GTF3C2, KIAA0011: General transcription factor 3C polypeptide 2 0.137 0.137
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.123 0.123
CDC40 CDC40, EHB3, PRP17, PRPF17: Pre-mRNA-processing factor 17 0.123 0.074
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.123 0.074
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.123 0.123
TAF5 TAF5, TAF2D: Transcription initiation factor TFIID subunit 5 0.123 0.123
WDR3 WDR3: WD repeat-containing protein 3 0.123 0.123
RBBP7 RBBP7, RBAP46: Histone-binding protein RBBP7 0.123 0.074
WDR77 WDR77, HKMT1069, hCG_39991: Androgen receptor cofactor p44 0.123 0.123
WDR12 WDR12: WD repeat-containing protein 12 0.123 0.074
STRAP STRAP, MAWD, UNRIP: Serine-threonine kinase receptor-associated protein 0.123 0.074
WDR68 WDR68, HAN11: WD repeat-containing protein 68 0.123 0.123
WDR57 WDR57, PRP8BP, SFP38: WD repeat-containing protein 57 0.123 0.074
RNU3IP2 RRP9, RNU3IP2, U355K: U3 small nucleolar RNA-interacting protein 2 0.123 0.074
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.123 0.074
WDR18 N/A 0.123 0.074
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.123 0.074
PPP2R2A PPP2R2A: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alp 0.123 0.074
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.123 0.074
LOC652595 RP11-395L14.12-001: OTTHUMP00000045488 0.119 0.119
LUC7L2 N/A 0.119 0.119
NULL N/A 0.119 0.119
LOC645472 hCG_23490: Uncharacterized protein ENSP00000329276 0.119 0.119
NUTF2 NUTF2, NTF2: Nuclear transport factor 2 0.0968 0.059
DDB2 DDB2: DNA damage-binding protein 2 0.083 0.083
FBXW2 FBXW2, FBW2, FWD2: F-box/WD repeat-containing protein 2 0.083 0.083
SERBP1 N/A 0.082 0.027
PTGES3 PTGES3, P23, TEBP: Prostaglandin E synthase 3 0.082 0.027
CORO1C CORO1C, CRNN4: Coronin-1C 0.074 0.044
FLJ10439 WDR74, NSA1: WD repeat-containing protein 74 0.074 0.074
SEC31L1 N/A 0.074 0.060
LRBA LRBA, BGL, CDC4L, LBA: Lipopolysaccharide-responsive and beige-like anchor prote 0.074 0.074
COPB2 COPB2: Coatomer subunit beta' 0.074 0.060
COPA COPA: Coatomer subunit alpha 0.074 0.060
TSSC1 TSSC1: Protein TSSC1 0.074 0.074
PWP2H PWP2, PWP2H: Periodic tryptophan protein 2 homolog 0.074 0.074
WDR8 WDR8: WD repeat-containing protein 8 0.067 0.067
WDR1 N/A 0.067 0.050
PLK3 PLK3, CNK, FNK, PRK: Serine/threonine-protein kinase PLK3 0.065 0.065
PIK3R4 PIK3R4: Phosphoinositide 3-kinase regulatory subunit 4 0.060 0.060
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.060 0.060
CORO7 CORO7: Coronin-7 0.060 0.044
WDR39 CIAO1, WDR39: Protein CIAO1 0.060 0.060
AAMP AAMP: Angio-associated migratory cell protein 0.060 0.060
GRWD1 GRWD1, GRWD, WDR28: Glutamate-rich WD repeat-containing protein 1 0.060 0.060
WDR26 WDR26, CDW2, PRO0852, MIP2: WD repeat-containing protein 26 0.060 0.044
AAAS AAAS, ADRACALA, GL003: Aladin 0.060 0.044
Nle NLE1, HUSSY-07: Notchless protein homolog 1 0.060 0.060
WIPI2 WIPI2, CGI-50: WD repeat domain phosphoinositide-interacting protein 2 0.060 0.060
PLK2 PLK2, SNK: Serine/threonine-protein kinase PLK2 0.053 0.047
GNB1L GNB1L, GY2, FKSG1, KIAA1645, WDR14: Guanine nucleotide-binding protein subunit b 0.050 0.050
THRAP5 MED16, DRIP92, THRAP5: Mediator of RNA polymerase II transcription subunit 16 0.044 0.044
NBEAL2 N/A 0.044 0.036
RAE1 RAE1, MRNP41: mRNA export factor 0.044 0.036
CORO1A CORO1A, CORO1: Coronin-1A 0.044 0.044
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.044 0.036
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.044 0.060
WDR67 WDR67: WD repeat-containing protein 67 0.044 0.060
EML3 EML3: Echinoderm microtubule-associated protein-like 3 0.044 0.060
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.044 0.036
ARPC1A ARPC1A, SOP2L: Actin-related protein 2/3 complex subunit 1A 0.044 0.036
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.044 0.044
WDR13 WDR13: WD repeat-containing protein 13 0.041 0.041
WDR48 WDR48, KIAA1449: WD repeat-containing protein 48 0.036 0.036
WDR45L N/A 0.036 0.028
WDR42A N/A 0.036 0.060
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.036 0.028
WIPI1 WIPI1, WIPI49: WD repeat domain phosphoinositide-interacting protein 1 0.036 0.028
WDR37 N/A 0.028 0.036
DYNC1I2 N/A 0.028 0.028
KATNB1 KATNB1: Katanin p80 WD40-containing subunit B1 0.028 0.028
ILF2 ILF2, NF45, PRO3063: Interleukin enhancer-binding factor 2 0.027 0.027
HNRPD N/A 0.027 0.027
NOLC1 NOLC1, KIAA0035: Nucleolar phosphoprotein p130 0.027 0.027
BUB3 N/A 0.027 0.027
DKFZP586L0724 NOL11, L14: Nucleolar protein 11 0.027 0.027
SMC4L1 N/A 0.027 0.027
WDR17 N/A 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
FBXW8 FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6: F-box/WD repeat-containing protein 8 0.027 0.027
KIF21A N/A 0.027 0.027
WDR53 N/A 0.027 0.027
TLE6 TLE6: Transducin-like enhancer protein 6 0.027 0.027
BRWD1 N/A 0.027 0.027
TAF5L TAF5L, PAF65B: TAF5-like RNA polymerase II p300/CBP-associated factor-associated 0.027 0.027
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.027 0.027
NEDD1 N/A 0.027 0.027
WDR34 N/A 0.027 0.027
WDR54 N/A 0.027 0.027
WDR72 N/A 0.027 0.027
ERCC8 ERCC8, CKN1, CSA: DNA excision repair protein ERCC-8 0.027 0.027
RFWD2 RFWD2, COP1, RNF200: E3 ubiquitin-protein ligase RFWD2 0.027 0.027
2.15E-3
Total Score 3.36