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Evidence of Interaction Between SNRPG and PRPF8

The interaction score between SNRPG and PRPF8 is 1.6.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between SNRPG and PRPF8 = 0.68

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 7.78E-3
Orthology
OrganismSNRPG OrthologuePRPF8 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YFL017W-A 1 YHR165C 1
  • AffinityCaptureMS

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worm Q9N4G9 1 P34369 1
fly Q9VXE0 1 Q960V2 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.593
Domains No domains were used in calculating likelihood of interaction N/A
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation No localisation data was used in calculating likelihood of interaction
Transitive Score

The common interactors between SNRPG and PRPF8 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between SNRPG andPRPF8. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , SNRPG has 256 interactors and PRPF8 has 84 interactors of which there are 39 common interactors.

Common InteractorName of Common InteractorScore for SNRPG-Interactor (?)Score for PRPF8-Interactor (?)
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 2.07E3 1.84
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 2.07E3 3.05
LSM5 LSM5: U6 snRNA-associated Sm-like protein LSm5 691.00 1.49
LSM4 LSM4: U6 snRNA-associated Sm-like protein LSm4 691.00 3.05
SNRPD2 SNRPD2, SNRPD1: Small nuclear ribonucleoprotein Sm D2 691.00 3.05
PRPF4 PRPF4, PRP4: U4/U6 small nuclear ribonucleoprotein Prp4 69.60 3.05
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 32.60 3.05
PRP19 PRPF19, NMP200, PRP19, SNEV: Pre-mRNA-processing factor 19 25.60 3.05
PLRG1 PLRG1: Pleiotropic regulator 1 6.33 0.593
SF3B3 N/A 3.89 1.84
SNRPA1 SNRPA1: U2 small nuclear ribonucleoprotein A' 3.89 3.05
SART1 SART1: U4/U6.U5 tri-snRNP-associated protein 1 3.05 3.05
LSM7 LSM7: U6 snRNA-associated Sm-like protein LSm7 2.60 3.05
SNRPF SNRPF, PBSCF: Small nuclear ribonucleoprotein F 2.60 1.84
LSM3 LSM3, MDS017: U6 snRNA-associated Sm-like protein LSm3 2.60 1.84
SF3A3 SF3A3, SAP61: Splicing factor 3A subunit 3 1.84 1.49
PRPF3 PRPF3, HPRP3, PRP3: U4/U6 small nuclear ribonucleoprotein Prp3 1.49 1.49
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 1.22 3.05
LSM6 LSM6: U6 snRNA-associated Sm-like protein LSm6 1.22 1.84
PRPF31 PRPF31, PRP31: U4/U6 small nuclear ribonucleoprotein Prp31 1.10 1.84
PRPF6 PRPF6, C20orf14: Pre-mRNA-processing factor 6 0.890 3.68
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.657 1.84
SF3B2 SF3B2, SAP145: Splicing factor 3B subunit 2 0.593 0.593
LUC7L N/A 0.593 0.593
PRPF40A PRPF40A, FBP11, HSPC225, FLAF1, FNBP3, HYPA: Pre-mRNA-processing factor 40 homol 0.593 0.593
SF3A1 SF3A1, SAP114: Splicing factor 3 subunit 1 0.412 1.84
SNRPEL1 RP11-390F4.1-001: Small nuclear ribonucleoprotein polypeptide E-like protein 1. 0.354 0.593
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.354 0.593
CROP CROP, CREAP1, O48: Cisplatin resistance-associated overexpressed protein 0.300 0.371
TFIP11 TFIP11, HSPC006: Tuftelin-interacting protein 11 0.249 1.49
LOC645472 hCG_23490: Uncharacterized protein ENSP00000329276 0.119 0.119
LOC652595 RP11-395L14.12-001: OTTHUMP00000045488 0.119 0.119
NULL N/A 0.119 0.119
LUC7L2 N/A 0.119 0.119
NULL N/A 0.119 0.119
LOC119358 similar to small nuclear ribonucleoprotein D2 0.071 0.119
PRPF40B DKFZp434O1520, PRPF40B, hCG_20201: Putative uncharacterized protein DKFZp434O152 0.071 0.119
PLK3 PLK3, CNK, FNK, PRK: Serine/threonine-protein kinase PLK3 0.065 0.138
PLK2 PLK2, SNK: Serine/threonine-protein kinase PLK2 0.053 0.078
2.15E-3
Total Score 1.6