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Evidence of Interaction Between LIG1 and FGR

The interaction score between LIG1 and FGR is 3.71.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between LIG1 and FGR = 0.09

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.85E-3
Orthology
OrganismLIG1 OrthologueFGR OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YDL164C 1 YBL007C 0.061
worm Q27474 1 Q9BKW3 0.411

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in LIG1 and FGR:
Domains in LIG1Domains in FGR
IPR000977 ATP-dependent DNA ligase
IPR012309 DNA_ligase_A_C.
IPR012310 DNA_ligase_A_M.
IPR012308 DNA_ligase_A_N.
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR001452 SH3
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in LIG1 and FGR are listed below.

Domain 1Domain 2Chi Square
IPR000977 ATP-dependent DNA ligase IPR001452 SH3 0.0316999

The background colour of the table refers to:

  • Blue Domain is only present in LIG1
  • Yellow Domain is only present in FGR
  • Green Domain is present in both LIG1 and FGR

 0.040
Post-translational Modifications

Protein: LIG1

PTMResidueReference
Phosphorylation 66 PubMed, HPRD
Phosphorylation 76 PubMed, HPRD
Phosphorylation 141 PubMed, HPRD
Phosphorylation 195 PubMed, HPRD
Phosphorylation 911 PubMed, HPRD
Phosphoserine 66 HPRD
Phosphoserine 76 HPRD
Phosphoserine 141 HPRD
Phosphoserine 911 HPRD
Phosphothreonine 195 HPRD

Protein: FGR

PTMResidueReference
Phosphorylation 412 PubMed, HPRD
Phosphorylation 523 PubMed, HPRD
Localisation

Protein: LIG1

LocalisationReference
Nucleus HPRD
Nucleoplasm HPRD

Protein: FGR

LocalisationReference
Cytoplasm HPRD
Transitive Score

The common interactors between LIG1 and FGR that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between LIG1 andFGR. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , LIG1 has 892 interactors and FGR has 1706 interactors of which there are 488 common interactors.

Common InteractorName of Common InteractorScore for LIG1-Interactor (?)Score for FGR-Interactor (?)
UBE2R2 UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2 3.39 0.025
CDC34 CDC34, UBE2R1: Ubiquitin-conjugating enzyme E2 R1 1.26 0.029
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.704 0.034
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.307 0.126
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.307 0.037
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.307 0.077
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.276 0.027
MCM3 MCM3: DNA replication licensing factor MCM3 0.276 0.033
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.251 0.080
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.191
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.144 0.0425
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.144 0.037
UBAP2 N/A 0.144 0.026
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.144 0.032
CENPA CENPA: Histone H3-like centromeric protein A 0.144 0.081
PTMA N/A 0.144 0.027
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.144 0.166
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.141 0.086
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.141 0.069
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.139 0.372
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.139 0.225
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.129 0.038
CDK4 CDK4: Cell division protein kinase 4 0.129 0.111
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.129 0.139
CDK2 CDK2: Cell division protein kinase 2 0.129 0.111
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.129 0.111
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.129 0.029
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.129 0.0818
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.129 0.136
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.129 0.051
WEE1 WEE1: Wee1-like protein kinase 0.129 0.123
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.129 0.111
NPM1 NPM1, NPM: Nucleophosmin 0.129 0.0453
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.129 0.051
H2AFX H2AFX, H2AX: Histone H2A.x 0.129 0.073
CDC20 CDC20: Cell division cycle protein 20 homolog 0.129 0.033
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.129 0.027
CCNB1 Cyclin B1 0.129 0.029
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.129 0.064
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.129 0.029
ROCK1 ROCK1: Rho-associated protein kinase 1 0.127 0.416
PLEK PLEK, P47: Pleckstrin 0.127 0.561
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.114 0.275
SOS1 SOS1: Son of sevenless homolog 1 0.114 0.113
CD2AP CD2AP: CD2-associated protein 0.112 0.171
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.111 4.07
DAB1 DAB1: Disabled homolog 1 0.111 0.088
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.097 0.111
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.091 0.152
CSK CSK: Tyrosine-protein kinase CSK 0.090 3.64
CRKL CRKL: Crk-like protein 0.090 1.35
DAB2 DAB2, DOC2: Disabled homolog 2 0.088 0.097
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.088 0.058
NBN NBN, NBS, NBS1, P95: Nibrin 0.087 0.036
KIF23 N/A 0.087 0.037
ABCF1 N/A 0.087 0.0425
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.087 0.027
DDX21 DDX21: Nucleolar RNA helicase 2 0.087 0.027
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.087 0.027
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.087 0.032
TRRAP N/A 0.087 0.026
GNB2L1 Lung cancer oncogene 7 0.087 0.027
FNBP1 N/A 0.087 10.60
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.086 0.763
DOK1 DOK1: Docking protein 1 0.086 0.461
NF2 NF2, SCH: Merlin 0.083 0.165
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.078 0.099
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.063
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.078 0.275
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.078 0.032
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.078 0.275
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.078 0.027
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.078 0.109
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.078 0.038
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.078 0.027
TP53 TP53, P53: Cellular tumor antigen p53 0.078 0.041
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.078 0.097
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.078 0.032
YY1 YY1: Transcriptional repressor protein YY1 0.078 0.032
TAF6 TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6 0.078 0.041
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.078 0.275
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.078 0.097
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.078 0.171
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.078 0.139
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.078 0.275
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.078 0.148
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.077 0.109
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.075 0.026
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.075 0.859
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.075 0.148
ELMO1 N/A 0.075 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.075 0.148
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.074 1.20
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.074 0.062
FUBP1 N/A 0.074 0.127
CXorf9 N/A 0.071 0.763
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.0425
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.070 0.123
CHUK N/A 0.070 0.0425
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.070 0.0446
KIAA0853 N/A 0.070 0.027
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.070 0.251
ELF1 ELF1: ETS-related transcription factor Elf-1 0.070 0.036
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.070 0.052
ARFGAP1 N/A 0.070 0.027
API5 N/A 0.070 0.026
IRF3 IRF3: Interferon regulatory factor 3 0.070 0.091
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.052
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.070 0.027
MYB MYB: Myb proto-oncogene protein 0.070 0.030
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.070 0.070
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.069 0.275
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.067 0.171
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.067 0.111
VIL2 N/A 0.067 0.171
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.067 0.171
VAV1 VAV1, VAV: Proto-oncogene vav 0.067 6.03
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.067 0.763
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.067 2.17
XPO1 XPO1, CRM1: Exportin-1 0.066 0.038
EIF2S3 EIF2S3, EIF2G: Eukaryotic translation initiation factor 2 subunit 3 0.066 0.046
COPS3 COPS3, CSN3: COP9 signalosome complex subunit 3 0.066 0.029
LAMR1 RPSA, LAMBR, LAMR1: 40S ribosomal protein SA 0.066 0.038
CCT8 CCT8: Uncharacterized protein CCT8 0.066 0.029
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.066 0.069
CTPS CTPS: CTP synthase 1 0.066 0.056
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.066 0.114
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.066 0.136
CDC23 CDC23: Cell division cycle protein 23 homolog 0.066 0.029
CCT6A CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta 0.066 0.029
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.063 0.071
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.063 0.073
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.063 0.0818
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.063 1.62
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.063 0.0425
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.063 0.137
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.063 0.032
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.063 0.109
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.063 0.029
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.063 0.027
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.063 0.038
NOC2L NOC2L: Nucleolar complex protein 2 homolog 0.063 0.029
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.063 0.111
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.063 0.245
SAPS3 N/A 0.063 0.046
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.063 0.046
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.062 0.515
GAB1 GAB1: GRB2-associated-binding protein 1 0.062 0.152
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.061 0.109
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.055 0.058
GAB2 N/A 0.055 0.307
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.054 86.60
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 0.054 1.07
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.052 0.057
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.052 0.152
NCOA3 N/A 0.052 0.036
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.052 0.036
SP100 N/A 0.052 0.027
IFI16 N/A 0.052 0.0446
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.052 0.251
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.052 0.036
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.051 0.617
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.051 0.372
APS SH2B2, APS: SH2B adapter protein 2 0.051 1.78
PLD1 PLD1: Phospholipase D1 0.051 0.111
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.051 86.60
MSN MSN: Moesin 0.051 0.763
IRS1 IRS1: Insulin receptor substrate 1 0.049 0.109
IRS2 IRS2: Insulin receptor substrate 2 0.049 0.515
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.049 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.049 0.165
LNK SH2B3, LNK: SH2B adapter protein 3 0.049 1.30
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.049 0.165
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.049 0.028
PSCD2 N/A 0.049 0.165
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.049 0.056
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.047 0.165
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.046 0.032
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.046 0.372
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.046 0.032
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.046 0.763
SYMPK SYMPK, SPK: Symplekin 0.046 0.029
EP300 N/A 0.046 0.032
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.046 0.136
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.046 0.032
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.046 0.181
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.046 0.503
SP3 SP3: Transcription factor Sp3 0.046 0.032
CLTC CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1 0.046 0.027
AIP AIP, XAP2: AH receptor-interacting protein 0.046 0.038
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.046 0.032
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.046 0.181
CDK7 CDK7, MO15: Cell division protein kinase 7 0.046 0.136
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.046 0.113
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.046 0.073
RPS6KB1 N/A 0.046 0.225
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.046 0.171
KIAA1012 KIAA1012: Protein TRS85 homolog 0.046 0.078
DIAPH1 Diaphanous 1 0.046 0.129
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.046 0.038
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.063
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.046 0.046
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.046 0.171
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.046 0.0818
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.038
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.046 0.225
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.046 0.111
KLHDC4 N/A 0.046 0.046
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.046 0.032
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.046 0.975
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.046 0.416
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.051
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.0453 0.070
VASP VASP: Vasodilator-stimulated phosphoprotein 0.0453 0.515
LIMK2 LIMK2: LIM domain kinase 2 0.0453 0.152
RANGAP1 RANGAP1, SD: Ran GTPase-activating protein 1 0.0446 0.026
PHB2 PHB2, BAP, REA: Prohibitin-2 0.0446 0.127
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.0446 0.062
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.044 0.099
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.044 0.081
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.044 0.148
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.044 0.025
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.075
MYO18A 0.044 0.028
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.044 1.30
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.025
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.044 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.044 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.044 0.148
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.044 1.30
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0425 0.0425
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.0425 0.098
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.0425 0.036
H1FX H1FX: Histone H1x 0.0425 0.091
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.0425 0.515
ZNF267 ZNF267: Zinc finger protein 267 0.0425 0.027
STK16 N/A 0.0425 0.152
WDR1 N/A 0.0425 0.036
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.0425 0.036
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.0425 0.191
NFATC1 N/A 0.0425 0.074
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.041 0.097
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.041 0.111
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.041 0.225
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.041 0.225
PSCD4 PSCD4, CYT4: Cytohesin-4 0.041 0.461
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.041 0.136
PLD2 PLD2: Phospholipase D2 0.041 0.111
RDX RDX: Radixin 0.041 0.088
RASA3 RASA3: Ras GTPase-activating protein 3 0.041 0.136
APBA3 APBA3, MINT3, X11L2: Amyloid beta A4 precursor protein-binding family A member 3 0.041 0.053
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.04 1.30
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.04 0.165
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.04 1.30
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.04 1.30
AMPH AMPH, AMPH1: Amphiphysin 0.04 0.165
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.040 0.114
FRG1 FRG1: Protein FRG1 0.040 0.046
EEF1G EEF1G, EF1G, PRO1608: Elongation factor 1-gamma 0.040 0.038
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.040 0.029
RPL8 RPL8: 60S ribosomal protein L8 0.040 0.046
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.040 0.063
QARS QARS: Glutaminyl-tRNA synthetase 0.040 0.063
HNRPK N/A 0.040 0.063
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.040 0.046
RPS3 RPS3, OK/SW-cl.26: 40S ribosomal protein S3 0.040 0.046
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.040 0.029
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.040 0.171
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.040 0.063
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.040 0.114
RPL3 RPL3, OK/SW-cl.32: 60S ribosomal protein L3 0.040 0.038
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.040 0.086
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.040 0.275
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.040 0.029
THOC1 THOC1, HPR1: THO complex subunit 1 0.040 0.069
EEF1B2 EEF1B2, EEF1B, EF1B: Elongation factor 1-beta 0.040 0.038
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.040 0.114
HSP90AA1 Hsp89-alpha-delta-N 0.040 0.069
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.040 0.038
NME2 NME2, NM23B: Nucleoside diphosphate kinase B 0.040 0.029
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.040 0.029
GSR GSR, GLUR, GRD1: Glutathione reductase, mitochondrial precursor 0.040 0.038
EIF3S6 EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6 0.040 0.063
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.038 0.051
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.038 0.032
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.038 0.251
SGTA SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A 0.038 0.029
BRPF1 BRPF1, BR140: Peregrin 0.038 0.038
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.038 0.040
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.038 0.763
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.038 0.070
COPA COPA: Coatomer subunit alpha 0.038 0.038
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.038 0.036
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.038 0.275
COPE COPE: Coatomer subunit epsilon 0.038 0.046
CDK6 CDK6: Cell division protein kinase 6 0.038 0.152
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.038 1.33
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.038 0.040
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.038 0.461
ATM ATM: Serine-protein kinase ATM 0.038 0.171
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.038 0.078
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.038 0.304
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.037 0.852
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.037 1.81
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.037 4.07
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.037 1.50
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.037 6.73
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.037 0.123
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.036 0.032
YWHAQ YWHAQ: 14-3-3 protein theta 0.036 0.026
STIP1 STIP1: Stress-induced-phosphoprotein 1 0.036 0.026
MNAR PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1 0.036 0.032
IPO7 IPO7: Uncharacterized protein IPO7 0.036 0.026
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.036 0.148
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.036 0.148
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 0.036 1.17
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.036 0.165
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 0.036 1.17
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.036 0.148
LYN LYN: Tyrosine-protein kinase Lyn 0.033 12.80
STAM2 STAM2: Signal transducing adapter molecule 2 0.033 0.171
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.033 1.50
NCK2 NCK2: Cytoplasmic protein NCK2 0.033 1.35
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.033 0.874
MCF2 MCF2, DBL: Proto-oncogene DBL 0.032 0.109
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.032 2.46
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.251
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.032 0.123
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.032 0.0425
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.032 0.166
PRKAA1 N/A 0.032 0.123
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.032 0.416
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.032 0.052
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.032 0.100
RGS14 N/A 0.032 0.036
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.032 0.070
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.032 0.152
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.032 0.307
STAT2 STAT2: Signal transducer and activator of transcription 2 0.032 1.13
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.032 0.062
CARS CARS: Cysteinyl-tRNA synthetase, cytoplasmic 0.032 0.046
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.032 0.046
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.032 0.188
RPS10 RPS10: 40S ribosomal protein S10 0.032 0.046
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.032 0.188
PPARBP N/A 0.032 0.052
TBCE TBCE: Tubulin-specific chaperone E 0.032 0.029
RARS RARS: Arginyl-tRNA synthetase, cytoplasmic 0.032 0.038
EEF1A1 EEF1A1: Elongation factor 1-alpha 0.032 0.046
EIF3S8 EIF3S8: Eukaryotic translation initiation factor 3 subunit 8 0.032 0.046
PSMC1 PSMC1: 26S protease regulatory subunit 4 0.032 0.038
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.032 0.086
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.032 0.139
PPID PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase 0.032 0.046
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.032 0.046
EEF2 EEF2, EF2: Elongation factor 2 0.032 0.038
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.032 1.78
VCP VCP: Transitional endoplasmic reticulum ATPase 0.032 0.029
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.0308 0.416
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.0308 0.088
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.029 0.088
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.029 0.099
BMX N/A 0.029 0.859
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.029 0.099
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.029 5.88
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.029 0.097
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.029 0.051
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.029 0.091
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.029 0.046
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.029 0.040
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.029 0.275
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.171
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.029 0.067
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.029 0.372
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.029 0.111
STK10 STK10: Uncharacterized protein STK10 0.029 0.763
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.029 0.141
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.275
GIT1 GIT1: ARF GTPase-activating protein GIT1 0.029 0.029
MTF1 MTF1: Metal regulatory transcription factor 1 0.029 0.040
GSK3B N/A 0.029 0.063
CCNH CCNH: Cyclin-H 0.029 0.041
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.029 0.461
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.029 0.372
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.029 0.111
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.029 0.032
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.029 0.136
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.083
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.109
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.028 0.165
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.165
PPEF1 N/A 0.028 0.165
MAPKAPK5 N/A 0.028 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.165
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.028 0.04
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.028 0.04
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.165
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.165
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.165
BID BID: BH3-interacting domain death agonist 0.028 0.049
MAPK15 N/A 0.028 0.165
PHLDB2 N/A 0.028 0.028
HES6 HES6: Transcription cofactor HES-6 0.028 0.049
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.028 0.049
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.165
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.028 0.088
SORBS3 SORBS3, SCAM1: Vinexin 0.027 0.097
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.027 0.694
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
HD HD, IT15: Huntingtin 0.027 0.155
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.0263 0.859
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.026 0.097
PSD TYL: TYL protein 0.026 0.097
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.026 0.099
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.026 0.087
GRLF1 N/A 0.026 0.109
ERF ERF: ETS domain-containing transcription factor ERF 0.026 0.0453
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.026
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.026 0.191
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.026 0.307
MDM4 MDM4, MDMX: Mdm4 protein 0.026 0.037
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.026 0.251
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.026 0.123
MARK2 N/A 0.026 0.087
SIPA1L3 SIPA1L3, KIAA0545, SPAL3: Signal-induced proliferation-associated 1-like protein 0.0253 0.033
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.148
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.148
MAP2K3 N/A 0.025 0.025
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.025 0.044
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.025 0.044
BCOR N/A 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.148
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.148
CCNT2 CCNT2: Cyclin-T2 0.025 0.044
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.025 0.148
ADK ADK: Adenosine kinase 0.025 0.025
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.366
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.025 0.148
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.025 0.148
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.025 0.098
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.148
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 0.098
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.148
CAMKK1 N/A 0.025 0.025
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.025 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.148
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.109
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.148
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
CAMK2A N/A 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
NIPBL N/A 0.025 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.025 0.148
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
GRK6 N/A 0.025 0.025
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.025 0.148
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.148
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.148
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
GIT2 N/A 0.025 0.025
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.025 0.148
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.098
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.098
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.025 0.098
CREB1 CREB1: cAMP response element-binding protein 0.025 0.044
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.025 0.148
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.148
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.098
EEF2K EEF2K: Elongation factor 2 kinase 0.025 0.148
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.025 0.878
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.148
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.098
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.025 0.148
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.025 0.044
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.025 0.148
PRKCB1 N/A 0.025 0.025
0.347
Total Score 3.71