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Evidence of Interaction Between SNRPG and SF3B1

The interaction score between SNRPG and SF3B1 is 81.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between SNRPG and SF3B1 = 0.57

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 6.27E-3
Orthology
OrganismSNRPG OrthologueSF3B1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YFL017W-A 1 YMR288W 1
  • Other
  • AffinityCaptureMS

Get References From PubMed
worm Q9N4G9 1 Q21909 1
fly Q9VXE0 1 Q9VPR5 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.593
Domains No domains were used in calculating likelihood of interaction 1.48E-3
Post-translational Modifications

Protein: SNRPG

PTMResidueReference

Protein: SF3B1

PTMResidueReference
Phosphorylation 344 PubMed, HPRD
Phosphorylation 350 PubMed, HPRD
Phosphorylation 354 PubMed, HPRD
Phosphoserine 344 HPRD
Phosphothreonine 350 HPRD
Phosphothreonine 354 HPRD
Localisation

Protein: SNRPG

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: SF3B1

LocalisationReference
Nucleus HPRD
Nucleoplasm HPRD
Cytoplasm HPRD
Paraspeckles HPRD
Transitive Score

The common interactors between SNRPG and SF3B1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between SNRPG andSF3B1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , SNRPG has 256 interactors and SF3B1 has 1429 interactors of which there are 78 common interactors.

Common InteractorName of Common InteractorScore for SNRPG-Interactor (?)Score for SF3B1-Interactor (?)
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 2.07E3 0.063
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 2.07E3 0.129
LSM4 LSM4: U6 snRNA-associated Sm-like protein LSm4 691.00 0.657
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 32.60 136.00
PRP19 PRPF19, NMP200, PRP19, SNEV: Pre-mRNA-processing factor 19 25.60 1.10
SF3B3 N/A 3.89 0.890
SNRPA1 SNRPA1: U2 small nuclear ribonucleoprotein A' 3.89 3.99
SNRPF SNRPF, PBSCF: Small nuclear ribonucleoprotein F 2.60 0.890
SF3A2 SF3A2, SAP62: Splicing factor 3A subunit 2 1.84 1.10
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 1.22 0.046
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.657 0.385
SF3B2 SF3B2, SAP145: Splicing factor 3B subunit 2 0.593 5.20
LUC7L N/A 0.593 0.593
SF3A1 SF3A1, SAP114: Splicing factor 3 subunit 1 0.412 4.67
SNRPEL1 RP11-390F4.1-001: Small nuclear ribonucleoprotein polypeptide E-like protein 1. 0.354 0.354
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.354 6.64
CROP CROP, CREAP1, O48: Cisplatin resistance-associated overexpressed protein 0.300 1.31
DHX15 DHX15, DBP1, DDX15: Putative pre-mRNA-splicing factor ATP-dependent RNA helicase 0.293 0.0278
DDX21 DDX21: Nucleolar RNA helicase 2 0.293 0.163
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.263 0.233
CDC20 CDC20: Cell division cycle protein 20 homolog 0.263 0.029
BAT1 N/A 0.263 0.053
DDX50 DDX50: ATP-dependent RNA helicase DDX50 0.137 0.0278
GNB2L1 Lung cancer oncogene 7 0.137 0.144
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.137 0.163
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.137 0.575
DDX47 E4-DBP: DEAD box protein 0.123 0.053
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.123 0.063
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.123 0.063
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.123 0.046
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.123 0.129
SND1 SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1 0.123 0.063
DDX18 DDX18: ATP-dependent RNA helicase DDX18 0.123 0.053
DDX23 DDX23: Probable ATP-dependent RNA helicase DDX23 0.123 0.053
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.123 0.046
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.123 0.029
LOC645472 hCG_23490: Uncharacterized protein ENSP00000329276 0.119 0.119
LOC652595 RP11-395L14.12-001: OTTHUMP00000045488 0.119 0.119
LUC7L2 N/A 0.119 0.119
FBXW2 FBXW2, FBW2, FWD2: F-box/WD repeat-containing protein 2 0.083 0.059
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.083 0.127
BLM BLM, RECQ2, RECQL3: Bloom syndrome protein 0.074 0.114
WRN WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase 0.074 0.114
CORO1C CORO1C, CRNN4: Coronin-1C 0.074 0.046
RECQL RECQL, RECQL1: ATP-dependent DNA helicase Q1 0.074 0.081
SEC31L1 N/A 0.074 0.078
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.074 0.515
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.074 0.515
COPB2 COPB2: Coatomer subunit beta' 0.074 0.046
COPA COPA: Coatomer subunit alpha 0.074 0.078
DDX41 DDX41, ABS: Probable ATP-dependent RNA helicase DDX41 0.074 0.118
WDR1 N/A 0.067 0.087
PLK3 PLK3, CNK, FNK, PRK: Serine/threonine-protein kinase PLK3 0.065 0.132
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.060 0.241
DDX17 DDX17: Probable ATP-dependent RNA helicase DDX17 0.060 0.053
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.060 0.086
REXO2 REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor 0.060 0.029
PLK2 PLK2, SNK: Serine/threonine-protein kinase PLK2 0.053 0.0421
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.044 0.046
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.044 1.54
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.044 0.046
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.044 0.054
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.044 0.146
ERCC3 ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit 0.044 0.118
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.044 0.118
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.044 0.078
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.044 0.063
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.044 0.146
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.044 0.233
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.036 0.146
DDX24 DDX24: ATP-dependent RNA helicase DDX24 0.036 0.118
NUP214 N/A 0.0308 0.032
BRIP1 BRIP1, BACH1, FANCJ: Fanconi anemia group J protein 0.028 0.043
C11orf58 SMAP, C11orf58: Small acidic protein 0.027 0.025
KARS KARS, KIAA0070: Lysyl-tRNA synthetase 0.027 0.0278
WDR54 N/A 0.027 0.028
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.027 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.027 0.052
0.228
Total Score 81.00