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The Barton Group

Predicted interactions involving protein SHC3, NSHC, SHCC: SHC-transforming protein 3 (IPI00409679) that score above 1.0

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
SHC3 PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 3.38E4 Evidence
SHC3 FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 2.47E4 Evidence
SHC3 DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 1.11E4 Evidence
SHC3 EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 8.52E3 Evidence
SHC3 ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 7.70E3 Evidence
SHC3 CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 6.62E3 Evidence
SHC3 KIT KIT: Mast/stem cell growth factor receptor precursor 6.36E3 Evidence
SHC3 ZAP70 ZAP70: Uncharacterized protein ZAP70 6.15E3 Evidence
SHC3 KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 5.60E3 Evidence
SHC3 STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 2.27E3 Evidence
SHC3 GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 1.37E3 Evidence
SHC3 STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 1.25E3 Evidence
SHC3 VAV1 VAV1, VAV: Proto-oncogene vav 1.06E3 Evidence
SHC3 NCK2 NCK2: Cytoplasmic protein NCK2 1.04E3 Evidence
SHC3 NCK1 NCK1, NCK: Cytoplasmic protein NCK1 945.0 Evidence
SHC3 CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 824.0 Evidence
SHC3 SOS1 SOS1: Son of sevenless homolog 1 743.0 Evidence
SHC3 CRKL CRKL: Crk-like protein 688.0 Evidence
SHC3 PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 150.0 Evidence
SHC3 FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 98.7 Evidence
SHC3 FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 64.80 Evidence
SHC3 FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 58.40 Evidence
SHC3 HCK N/A 58.40 Evidence
SHC3 MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 57.40 Evidence
SHC3 PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 53.20 Evidence
SHC3 LTK LTK, TYK1: Leukocyte tyrosine kinase receptor precursor 53.20 Evidence
SHC3 INSR INSR: Insulin receptor precursor 53.20 Evidence
SHC3 ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 50.10 Evidence
SHC3 ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 44.50 Evidence
SHC3 PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 32.90 Evidence
SHC3 ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 28.30 Evidence
SHC3 FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 25.90 Evidence
SHC3 AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 25.90 Evidence
SHC3 FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 25.90 Evidence
SHC3 PTK6 PTK6, BRK: Tyrosine-protein kinase 6 24.10 Evidence
SHC3 TEK TEK, TIE2: Angiopoietin-1 receptor precursor 23.90 Evidence
SHC3 SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 23.50 Evidence
SHC3 RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 23.20 Evidence
SHC3 MET MET: Hepatocyte growth factor receptor precursor 22.50 Evidence
SHC3 FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 21.60 Evidence
SHC3 JAK2 JAK2: Tyrosine-protein kinase JAK2 21.60 Evidence
SHC3 EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 17.70 Evidence
SHC3 EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 17.30 Evidence
SHC3 MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 17.30 Evidence
SHC3 EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 17.30 Evidence
SHC3 FLT3 FLT3, STK1: FL cytokine receptor precursor 15.20 Evidence
SHC3 MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 15.10 Evidence
SHC3 ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 14.20 Evidence
SHC3 JAK1 12.70 Evidence
SHC3 SYK SYK: Tyrosine-protein kinase SYK 12.70 Evidence
SHC3 ABR ABR: Active breakpoint cluster region-related protein 9.95 Evidence
SHC3 PRKCG PRKCG, PKCG: Protein kinase C gamma type 9.16 Evidence
SHC3 STAT6 STAT6: Signal transducer and activator of transcription 6 6.64 Evidence
SHC3 GRAP GRAP: GRB2-related adapter protein 6.54 Evidence
SHC3 GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 5.89 Evidence
SHC3 PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 5.30 Evidence
SHC3 ROBO1 N/A 4.80 Evidence
SHC3 GRB14 GRB14: Growth factor receptor-bound protein 14 4.56 Evidence
SHC3 SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 4.34 Evidence
SHC3 GAB1 GAB1: GRB2-associated-binding protein 1 4.27 Evidence
SHC3 GRB7 GRB7: Growth factor receptor-bound protein 7 4.01 Evidence
SHC3 PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 3.70 Evidence
SHC3 SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 3.6 Evidence
SHC3 EREG EREG: Proepiregulin precursor [Contains: Epiregulin 3.58 Evidence
SHC3 MAP2K7 MAP2K7, JNKK2, MEK7, MKK7, PRKMK7: Dual specificity mitogen-activated protein ki 3.41 Evidence
SHC3 STAT3 3.31 Evidence
SHC3 RASA1 RASA1, RASA: Ras GTPase-activating protein 1 3.31 Evidence
SHC3 VAV3 VAV3: Protein vav-3 3.24 Evidence
SHC3 ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 3.18 Evidence
SHC3 BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 3.18 Evidence
SHC3 LNK SH2B3, LNK: SH2B adapter protein 3 3.18 Evidence
SHC3 CD160 CD160, BY55: CD160 antigen precursor 3.15 Evidence
SHC3 AREG AREG, SDGF: Amphiregulin precursor 3.15 Evidence
SHC3 TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 3.15 Evidence
SHC3 PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 3.05 Evidence
SHC3 CTTN CTTN, EMS1: Src substrate cortactin 2.93 Evidence
SHC3 PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 2.91 Evidence
SHC3 SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 2.85 Evidence
SHC3 SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 2.76 Evidence
SHC3 BTC BTC: Probetacellulin precursor [Contains: Betacellulin 2.68 Evidence
SHC3 FRS3 FRS3: Fibroblast growth factor receptor substrate 3 2.63 Evidence
SHC3 WASL WASL: Neural Wiskott-Aldrich syndrome protein 2.63 Evidence
SHC3 PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 2.60 Evidence
SHC3 PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 2.50 Evidence
SHC3 CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 2.50 Evidence
SHC3 LAT LAT: Linker for activation of T-cells family member 1 2.50 Evidence
SHC3 ADAM15 ADAM15, MDC15: ADAM 15 precursor 2.50 Evidence
SHC3 PLD2 PLD2: Phospholipase D2 2.47 Evidence
SHC3 PLD1 PLD1: Phospholipase D1 2.47 Evidence
SHC3 PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 2.47 Evidence
SHC3 IRS2 IRS2: Insulin receptor substrate 2 2.37 Evidence
SHC3 IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 2.37 Evidence
SHC3 H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 2.24 Evidence
SHC3 MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 2.19 Evidence
SHC3 RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 2.19 Evidence
SHC3 MDN1 MDN1, KIAA0301: Midasin 2.18 Evidence
SHC3 PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 2.17 Evidence
SHC3 DAB1 DAB1: Disabled homolog 1 2.13 Evidence
SHC3 MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 2.13 Evidence
SHC3 APS SH2B2, APS: SH2B adapter protein 2 2.13 Evidence
SHC3 VIL2 N/A 1.96 Evidence
SHC3 STAM2 STAM2: Signal transducing adapter molecule 2 1.96 Evidence
SHC3 DCC DCC: Netrin receptor DCC precursor 1.94 Evidence
SHC3 CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 1.91 Evidence
SHC3 EGF EGF: Pro-epidermal growth factor precursor 1.91 Evidence
SHC3 CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 1.91 Evidence
SHC3 PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 1.91 Evidence
SHC3 CD2AP CD2AP: CD2-associated protein 1.90 Evidence
SHC3 WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 1.90 Evidence
SHC3 BLNK BLNK, BASH, SLP65: B-cell linker protein 1.89 Evidence
SHC3 SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 1.89 Evidence
SHC3 SCAP2 SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2 1.89 Evidence
SHC3 SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 1.89 Evidence
SHC3 FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 1.87 Evidence
SHC3 CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 1.87 Evidence
SHC3 F12 F12: Coagulation factor XII precursor 1.78 Evidence
SHC3 AMBP AMBP, HCP, ITIL: AMBP protein precursor [Contains: Alpha-1-microglobulin 1.78 Evidence
SHC3 PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 1.74 Evidence
SHC3 HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 1.72 Evidence
SHC3 PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 1.69 Evidence
SHC3 DAB2 DAB2, DOC2: Disabled homolog 2 1.69 Evidence
SHC3 PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 1.69 Evidence
SHC3 IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 1.64 Evidence
SHC3 EPOR EPOR: Erythropoietin receptor precursor 1.64 Evidence
SHC3 GHR GHR: Growth hormone receptor precursor 1.64 Evidence
SHC3 CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 1.64 Evidence
SHC3 ITGB4 N/A 1.64 Evidence
SHC3 MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 1.62 Evidence
SHC3 SYNJ1 SYNJ1, KIAA0910: Synaptojanin-1 1.61 Evidence
SHC3 IRS1 IRS1: Insulin receptor substrate 1 1.59 Evidence
SHC3 TNC TNC, HXB: Tenascin precursor 1.54 Evidence
SHC3 CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 1.54 Evidence
SHC3 STAT5B STAT5B: Signal transducer and activator of transcription 5B 1.54 Evidence
SHC3 CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 1.48 Evidence
SHC3 SCML2 SCML2: Sex comb on midleg-like protein 2 1.48 Evidence
SHC3 CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 1.48 Evidence
SHC3 SOS2 SOS2: Son of sevenless homolog 2 1.47 Evidence
SHC3 RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 1.45 Evidence
SHC3 PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 1.43 Evidence
SHC3 ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 1.29 Evidence
SHC3 PROZ PROZ: Vitamin K-dependent protein Z precursor 1.22 Evidence
SHC3 EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 1.17 Evidence
SHC3 LCP2 LCP2: Lymphocyte cytosolic protein 2 1.13 Evidence
SHC3 MET N/A 1.07 Evidence
SHC3 CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 1.02 Evidence
SHC3 PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 1.01 Evidence