Predicted interactions involving protein EGFR, ERBB1: Epidermal growth factor receptor precursor (IPI00018274) that score above 12.5

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module Score	Databases
	Where interaction is observed in another database a link is provided: - BIND - DIP - HPRD O - OPHID

Protein 1 (?)	Protein 2 (?)	Name of Protein 2	Module Scores (?)				Scores (?)	Evidence (?)	Database (?)
EGFR	ERBB2	ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor					9.88E3	Evidence
EGFR	SHC3	SHC3, NSHC, SHCC: SHC-transforming protein 3					8.52E3	Evidence
EGFR	ERBB3	ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor					4.98E3	Evidence
EGFR	FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn					200.0	Evidence
EGFR	NCK2	NCK2: Cytoplasmic protein NCK2					200.0	Evidence
EGFR	GRB2	GRB2, ASH: Growth factor receptor-bound protein 2					200.0	Evidence
EGFR	STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A					200.0	Evidence
EGFR	JAK2	JAK2: Tyrosine-protein kinase JAK2					200.0	Evidence
EGFR	TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec					200.0	Evidence
EGFR	KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate					125.0	Evidence
EGFR	NCK1	NCK1, NCK: Cytoplasmic protein NCK1					121.0	Evidence
EGFR	ZAP70	ZAP70: Uncharacterized protein ZAP70					121.0	Evidence
EGFR	PIK3R2	PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta					121.0	Evidence
EGFR	CRKL	CRKL: Crk-like protein					121.0	Evidence
EGFR	SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src					117.0	Evidence
EGFR	STAT3						117.0	Evidence
EGFR	PTK6	PTK6, BRK: Tyrosine-protein kinase 6					117.0	Evidence
EGFR	STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta					110.0	Evidence
EGFR	STAT5B	STAT5B: Signal transducer and activator of transcription 5B					110.0	Evidence
EGFR	ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1					89.20	Evidence
EGFR	BMX	N/A					89.20	Evidence
EGFR	LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK					89.20	Evidence
EGFR	INSL3	JAK3: Tyrosine-protein kinase JAK3					89.20	Evidence
EGFR	LYN	LYN: Tyrosine-protein kinase Lyn					89.20	Evidence
EGFR	BLNK	BLNK, BASH, SLP65: B-cell linker protein					89.20	Evidence
EGFR	TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2					79.90	Evidence
EGFR	SYK	SYK: Tyrosine-protein kinase SYK					79.90	Evidence
EGFR	RASA1	RASA1, RASA: Ras GTPase-activating protein 1					79.90	Evidence
EGFR	HCK	N/A					79.90	Evidence
EGFR	JAK1						79.90	Evidence
EGFR	CBL	CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL					67.1	Evidence
EGFR	LCP2	LCP2: Lymphocyte cytosolic protein 2					64.40	Evidence
EGFR	CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B					44.00	Evidence
EGFR	PTK2	PTK2, FAK, FAK1: Focal adhesion kinase 1					40.60	Evidence
EGFR	PDGFRB	PDGFRB: Beta-type platelet-derived growth factor receptor precursor					33.90	Evidence
EGFR	INSR	INSR: Insulin receptor precursor					33.90	Evidence
EGFR	KIT	KIT: Mast/stem cell growth factor receptor precursor					33.90	Evidence
EGFR	PDGFRA	PDGFRA: Alpha-type platelet-derived growth factor receptor precursor					33.90	Evidence
EGFR	GRB7	GRB7: Growth factor receptor-bound protein 7					30.10	Evidence
EGFR	GRAP	GRAP: GRB2-related adapter protein					23.20	Evidence
EGFR	KDR	KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor					20.50	Evidence
EGFR	PTPN2	PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2					20.50	Evidence
EGFR	CSF1R	CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor					20.50	Evidence
EGFR	IL6ST	IL6ST: Interleukin-6 receptor subunit beta precursor					19.70	Evidence
EGFR	AXL	AXL, UFO: Tyrosine-protein kinase receptor UFO precursor					19.70	Evidence
EGFR	TGFA	TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow					19.70	Evidence
EGFR	EGF	EGF: Pro-epidermal growth factor precursor					19.70	Evidence
EGFR	ICAM3	ICAM3: Intercellular adhesion molecule 3 precursor					19.70	Evidence
EGFR	ITGB4	N/A					19.70	Evidence
EGFR	BTC	BTC: Probetacellulin precursor [Contains: Betacellulin					19.70	Evidence
EGFR	HLA-A	HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor					19.70	Evidence
EGFR	ERBB4	ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor					17.60	Evidence
EGFR	IGF1R	IGF1R: Insulin-like growth factor 1 receptor precursor					17.60	Evidence
EGFR	JAG2	JAG2: Jagged-2 precursor					17.60	Evidence
EGFR	EPOR	EPOR: Erythropoietin receptor precursor					15.00	Evidence
EGFR	GHR	GHR: Growth hormone receptor precursor					15.00	Evidence
EGFR	IQGAP1	IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1					13.50	Evidence
EGFR	SH3KBP1	SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1					13.50	Evidence
EGFR	STAM2	STAM2: Signal transducing adapter molecule 2					13.50	Evidence
EGFR	IGFBP7	IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor					13.00	Evidence
EGFR	MT2A	MT2A, CES1, MT2: Metallothionein-2					13.00	Evidence
EGFR	VASP	VASP: Vasodilator-stimulated phosphoprotein					13.00	Evidence
EGFR	NF2	NF2, SCH: Merlin					13.00	Evidence