Click on the protein name for more information about the protein.
The Score column is the predicted score of interaction between the two proteins
Click on the Evidence link to view a breakdown of the information about the predicted interaction.
| Key | |
|---|---|
| Module Score | Databases |
 | Where interaction is observed in another database a link is provided: |
| Protein 1 (?) | Protein 2 (?) | Name of Protein 2 | Module Scores (?) | Scores (?) | Evidence (?) | Database (?) | |||
|---|---|---|---|---|---|---|---|---|---|
 |  |  |  | ||||||
| BTK | JAK2 | JAK2: Tyrosine-protein kinase JAK2 | 835.0 | Evidence | |||||
| BTK | TYK2 | TYK2: Non-receptor tyrosine-protein kinase TYK2 | 720.0 | Evidence | |||||
| BTK | SYK | SYK: Tyrosine-protein kinase SYK | 720.0 | Evidence |
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| BTK | CRKL | CRKL: Crk-like protein | 674.0 | Evidence | |||||
| BTK | LYN | LYN: Tyrosine-protein kinase Lyn | 613.0 | Evidence |
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| BTK | FGR | FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR | 565.0 | Evidence | |||||
| BTK | CSK | CSK: Tyrosine-protein kinase CSK | 549.0 | Evidence | |||||
| BTK | STAT5A | STAT5A, STAT5: Signal transducer and activator of transcription 5A | 497.0 | Evidence |
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| BTK | HCK | N/A | 392.0 | Evidence |
O
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| BTK | BLNK | BLNK, BASH, SLP65: B-cell linker protein | 370.0 | Evidence |
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| BTK | VAV1 | VAV1, VAV: Proto-oncogene vav | 332.0 | Evidence |
O
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| BTK | STAT5B | STAT5B: Signal transducer and activator of transcription 5B | 305.0 | Evidence | |||||
| BTK | SH3BP2 | SH3BP2: Uncharacterized protein SH3BP2 | 299.0 | Evidence | |||||
| BTK | FYN | FYN: Proto-oncogene tyrosine-protein kinase Fyn | 299.0 | Evidence | |||||
| BTK | NCK1 | NCK1, NCK: Cytoplasmic protein NCK1 | 259.0 | Evidence | |||||
| BTK | KIT | KIT: Mast/stem cell growth factor receptor precursor | 206.0 | Evidence |
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| BTK | APS | SH2B2, APS: SH2B adapter protein 2 | 198.0 | Evidence |
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| BTK | SLA | SLA, SLAP, SLAP1: SRC-like-adapter | 181.0 | Evidence | |||||
| BTK | SRC | SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src | 181.0 | Evidence | |||||
| BTK | LCP2 | LCP2: Lymphocyte cytosolic protein 2 | 177.0 | Evidence | |||||
| BTK | JAK1 | 162.0 | Evidence |
O
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| BTK | STAT3 | 156.0 | Evidence | ||||||
| BTK | PDGFRB | PDGFRB: Beta-type platelet-derived growth factor receptor precursor | 149.0 | Evidence | |||||
| BTK | GRB2 | GRB2, ASH: Growth factor receptor-bound protein 2 | 139.0 | Evidence | O | ||||
| BTK | STAT1 | STAT1: Signal transducer and activator of transcription 1-alpha/beta | 135.0 | Evidence | |||||
| BTK | CSF1R | CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor | 135.0 | Evidence | |||||
| BTK | ZAP70 | ZAP70: Uncharacterized protein ZAP70 | 121.0 | Evidence | |||||
| BTK | ABL2 | ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 | 119.0 | Evidence | |||||
| BTK | PTPN6 | PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 | 119.0 | Evidence | |||||
| BTK | ABL1 | ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 | 109.0 | Evidence |
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| BTK | PTK2B | PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta | 106.0 | Evidence | |||||
| BTK | ITK | ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK | 106.0 | Evidence |
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| BTK | RASA1 | RASA1, RASA: Ras GTPase-activating protein 1 | 106.0 | Evidence | |||||
| BTK | TEC | TEC, PSCTK4: Tyrosine-protein kinase Tec | 98.20 | Evidence |
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| BTK | WASPIP | N/A | 95.20 | Evidence | |||||
| BTK | CBLB | CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B | 92.20 | Evidence | |||||
| BTK | PDGFRA | PDGFRA: Alpha-type platelet-derived growth factor receptor precursor | 90.70 | Evidence | |||||
| BTK | LCK | LCK: Proto-oncogene tyrosine-protein kinase LCK | 88.80 | Evidence | |||||
| BTK | KHDRBS1 | KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate | 87.80 | Evidence |
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| BTK | KDR | KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor | 80.00 | Evidence | |||||
| BTK | INSR | INSR: Insulin receptor precursor | 80.00 | Evidence | |||||
| BTK | INSL3 | JAK3: Tyrosine-protein kinase JAK3 | 78.20 | Evidence | |||||
| BTK | PTK6 | PTK6, BRK: Tyrosine-protein kinase 6 | 78.20 | Evidence | |||||
| BTK | BMX | N/A | 78.20 | Evidence |
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| BTK | CBL | CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL | 78.20 | Evidence |
O
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| BTK | MAP4K1 | MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 | 77.50 | Evidence | |||||
| BTK | PIK3R2 | PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta | 70.10 | Evidence | |||||
| BTK | HCLS1 | HCLS1, HS1: Hematopoietic lineage cell-specific protein | 69.40 | Evidence | |||||
| BTK | TEK | TEK, TIE2: Angiopoietin-1 receptor precursor | 59.50 | Evidence | |||||
| BTK | WAS | WAS, IMD2: Wiskott-Aldrich syndrome protein | 55.10 | Evidence |
O
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| BTK | CBLC | CBLC, CBL3, RNF57: Signal transduction protein CBL-C | 52.80 | Evidence | |||||
| BTK | EPHB3 | EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor | 47.30 | Evidence | |||||
| BTK | CDK7 | CDK7, MO15: Cell division protein kinase 7 | 38.10 | Evidence | |||||
| BTK | PIK3CG | PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i | 37.80 | Evidence | |||||
| BTK | GRAP | GRAP: GRB2-related adapter protein | 36.40 | Evidence | |||||
| BTK | NMT1 | NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 | 35.00 | Evidence | |||||
| BTK | DOK1 | DOK1: Docking protein 1 | 33.90 | Evidence | |||||
| BTK | SOCS1 | SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 | 32.80 | Evidence | |||||
| BTK | CDK2 | CDK2: Cell division protein kinase 2 | 25.00 | Evidence | |||||
| BTK | TUBA1 | TUBA4A, TUBA1: Tubulin alpha-4A chain | 24.90 | Evidence | |||||
| BTK | CD79A | CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain | 24.90 | Evidence | |||||
| BTK | CD22 | CD22, SIGLEC2: B-cell receptor CD22 precursor | 24.90 | Evidence | |||||
| BTK | BRDG1 | STAP1, BRDG1: Signal-transducing adaptor protein 1 | 24.10 | Evidence | |||||
| BTK | ACTG1 | ACTB: Actin, cytoplasmic 1 | 21.20 | Evidence | |||||
| BTK | NRBP1 | NRBP1, BCON3, NRBP: Nuclear receptor-binding protein | 20.50 | Evidence | |||||
| BTK | PRKDC | PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit | 19.10 | Evidence | |||||
| BTK | CSF2RB | CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor | 18.40 | Evidence | |||||
| BTK | CXCR4 | CXCR4: C-X-C chemokine receptor type 4 | 18.40 | Evidence | |||||
| BTK | IL10RA | IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor | 18.40 | Evidence | |||||
| BTK | SOCS5 | SOCS5, CIS6, CISH5, CISH6, KIAA0671: Suppressor of cytokine signaling 5 | 15.80 | Evidence | |||||
| BTK | CDC2 | CDC2: Cell division control protein 2 homolog | 15.00 | Evidence | |||||
| BTK | DUSP16 | DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 | 15.00 | Evidence | |||||
| BTK | SNCA | SNCA, NACP, PARK1: Alpha-synuclein | 15.00 | Evidence | |||||
| BTK | SH3KBP1 | SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 | 15.00 | Evidence | |||||
| BTK | PASK | PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase | 13.80 | Evidence | |||||
| BTK | PTPN2 | PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 | 13.50 | Evidence | |||||
| BTK | SOS1 | SOS1: Son of sevenless homolog 1 | 13.50 | Evidence | |||||
| BTK | NEDD9 | NEDD9, CASL: Enhancer of filamentation 1 | 13.40 | Evidence | |||||
| BTK | MAPK3 | MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 | 13.2 | Evidence | |||||
| BTK | AMHR2 | AMHR2, AMHR: Anti-Muellerian hormone type-2 receptor precursor | 13.00 | Evidence | |||||
| BTK | SCAP2 | SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2 | 12.50 | Evidence | |||||
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