Predicted interactions involving protein EGFR, ERBB1: Epidermal growth factor receptor precursor (IPI00018274) that score above 25.0

Click on the protein name for more information about the protein.

The Score column is the predicted score of interaction between the two proteins

Click on the Evidence link to view a breakdown of the information about the predicted interaction.

Key
Module ScoreDatabases
Where interaction is observed in another database a link is provided:

Protein 1 (?)Protein 2 (?) Name of Protein 2 Module Scores (?) Scores (?) Evidence (?) Database (?)
EGFR ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 9.88E3 Evidence
EGFR SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 8.52E3 Evidence
EGFR ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 4.98E3 Evidence
EGFR FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 200.0 Evidence
EGFR STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 200.0 Evidence
EGFR TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 200.0 Evidence
EGFR NCK2 NCK2: Cytoplasmic protein NCK2 200.0 Evidence
EGFR GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 200.0 Evidence
EGFR JAK2 JAK2: Tyrosine-protein kinase JAK2 200.0 Evidence
EGFR KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 125.0 Evidence
EGFR CRKL CRKL: Crk-like protein 121.0 Evidence
EGFR NCK1 NCK1, NCK: Cytoplasmic protein NCK1 121.0 Evidence
EGFR PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 121.0 Evidence
EGFR ZAP70 ZAP70: Uncharacterized protein ZAP70 121.0 Evidence
EGFR SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 117.0 Evidence
EGFR STAT3 117.0 Evidence
EGFR PTK6 PTK6, BRK: Tyrosine-protein kinase 6 117.0 Evidence
EGFR STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 110.0 Evidence
EGFR STAT5B STAT5B: Signal transducer and activator of transcription 5B 110.0 Evidence
EGFR ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 89.20 Evidence
EGFR BLNK BLNK, BASH, SLP65: B-cell linker protein 89.20 Evidence
EGFR BMX N/A 89.20 Evidence
EGFR LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 89.20 Evidence
EGFR INSL3 JAK3: Tyrosine-protein kinase JAK3 89.20 Evidence
EGFR LYN LYN: Tyrosine-protein kinase Lyn 89.20 Evidence
EGFR JAK1 79.90 Evidence
EGFR RASA1 RASA1, RASA: Ras GTPase-activating protein 1 79.90 Evidence
EGFR HCK N/A 79.90 Evidence
EGFR SYK SYK: Tyrosine-protein kinase SYK 79.90 Evidence
EGFR TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 79.90 Evidence
EGFR CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 67.1 Evidence
EGFR LCP2 LCP2: Lymphocyte cytosolic protein 2 64.40 Evidence
EGFR CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 44.00 Evidence
EGFR PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 40.60 Evidence
EGFR PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 33.90 Evidence
EGFR INSR INSR: Insulin receptor precursor 33.90 Evidence
EGFR PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 33.90 Evidence
EGFR KIT KIT: Mast/stem cell growth factor receptor precursor 33.90 Evidence
EGFR GRB7 GRB7: Growth factor receptor-bound protein 7 30.10 Evidence