Home
Advanced Search
Help
Update History
Statistics
Downloads
The Barton Group
<<< Back to TUBB2

Evidence of Interaction Between TUBB2 and IKBKE

The interaction score between TUBB2 and IKBKE is 0.250.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismTUBB2 OrthologueIKBKE OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00646779 0.608 IPI00293613 0.194
human IPI00006510 0.093 IPI00293613 0.194
human IPI00152453 0.521 IPI00293613 0.194
human IPI00292496 0.634 IPI00293613 0.194
human IPI00174849 0.51 IPI00293613 0.194
human IPI00335160 0.387 IPI00293613 0.194
human IPI00738097 0.253 IPI00293613 0.194
human IPI00182840 0.335 IPI00293613 0.194
human IPI00013475 0.871 IPI00293613 0.194
human IPI00031370 0.902 IPI00293613 0.194
human IPI00160897 0.918 IPI00293613 0.194
  • Other

Get References From PubMed
fly P61857 1 Q8INU8 0.194

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 1.07
Domains Domains present in TUBB2 and IKBKE:
Domains in TUBB2Domains in IKBKE
IPR000217 Tubulin
IPR008280 Tubulin/FtsZ, C-terminal
IPR003008 Tubulin/FtsZ, GTPase
IPR002453 Beta tubulin
IPR000158 Cell division protein FtsZ
IPR000719 Protein kinase
IPR002290 Serine/threonine protein kinase
IPR011009 Protein kinase-like
IPR008271 Serine/threonine protein kinase, active site

The Chi square scores for co-occurrence of domains that are present in TUBB2 and IKBKE are listed below.

Domain 1Domain 2Chi Square
IPR002453 Beta tubulin IPR011009 Protein kinase-like 0.606706
IPR000217 Tubulin IPR011009 Protein kinase-like 0.524874
IPR002453 Beta tubulin IPR008271 Serine/threonine protein kinase, active site 0.231192
IPR003008 Tubulin/FtsZ, GTPase IPR011009 Protein kinase-like 0.224946
IPR008280 Tubulin/FtsZ, C-terminal IPR011009 Protein kinase-like 0.224946
IPR003008 Tubulin/FtsZ, GTPase IPR008271 Serine/threonine protein kinase, active site 0.0632222
IPR008280 Tubulin/FtsZ, C-terminal IPR008271 Serine/threonine protein kinase, active site 0.0632222
IPR000217 Tubulin IPR008271 Serine/threonine protein kinase, active site 0.0424984
IPR008280 Tubulin/FtsZ, C-terminal IPR002290 Serine/threonine protein kinase 0.0364946
IPR003008 Tubulin/FtsZ, GTPase IPR002290 Serine/threonine protein kinase 0.0364946
IPR000217 Tubulin IPR000719 Protein kinase 0.0254403
IPR008280 Tubulin/FtsZ, C-terminal IPR000719 Protein kinase 0.0107937
IPR003008 Tubulin/FtsZ, GTPase IPR000719 Protein kinase 0.0107937
IPR000217 Tubulin IPR002290 Serine/threonine protein kinase 0.00321315
IPR002453 Beta tubulin IPR000719 Protein kinase 0.00159219

The background colour of the table refers to:

  • Blue Domain is only present in TUBB2
  • Yellow Domain is only present in IKBKE
  • Green Domain is present in both TUBB2 and IKBKE

 6.5E-4
Post-translational Modifications

Protein: TUBB2

PTMResidueReference

Protein: IKBKE

PTMResidueReference
Phosphoserine 172 HPRD
Localisation

Protein: TUBB2

LocalisationReference
Nucleolus HPRD
Cytoplasm HPRD

Protein: IKBKE

LocalisationReference
Cytoplasm HPRD
Transitive Score No Transitive data was used in the prediction of this interaction. N/A
Total Score 0.250