|What Does PIPs Do ...||Help Document|
PIPs is a database of predicted human protein-protein interactions. The predictions have been made using a naïve Bayesian classifier to calculate a Score of interaction. There are 37606 interactions with a Score ≥1 indicating that the interaction is more likely to occur than not to occur.
The probability of interaction between two proteins is calculated by combining different features including:
|Gene Co-expression||Orthology||Domain Co-occurrence|
|Co-localisation||Post Translational Modification||Network Analysis (Transitive)|
Scott, MS and Barton, GJ Probabilistic prediction and ranking of human protein-protein interactions BMC Bioinformatics 2007 8:239-260 Abstract