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Evidence of Interaction Between PDGFRB and CRKL

The interaction score between PDGFRB and CRKL is 1.22E5.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between PDGFRB and CRKL = -0.30

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.30E-3
Orthology
OrganismPDGFRB OrthologueCRKL OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00022296 0.132 IPI00013864 0.053
  • Other
  • InVitro
  • InVivo

Get References From PubMed
human IPI00027721 0.325 IPI00013864 0.053
human IPI00018335 1 IPI00013864 0.053
human IPI00021396 1 IPI00013864 0.053
human IPI00293565 0.322 IPI00013864 0.053
human IPI00005722 0.081 IPI00013864 0.053
human IPI00022296 0.132 IPI00399054 0.438
  • InVitro
  • InVivo

Get References From PubMed
human IPI00027721 0.325 IPI00399054 0.438
  • InVitro
  • InVivo

Get References From PubMed
human IPI00018335 1 IPI00399054 0.438
  • InVitro

Get References From PubMed
human IPI00021396 1 IPI00399054 0.438
  • InVitro

Get References From PubMed
human IPI00293565 0.322 IPI00399054 0.438
human IPI00005722 0.081 IPI00399054 0.438
worm P34892 0.084 Q9NHC3 0.438
worm O76698 1 Q9NHC3 0.438
worm Q21038 1 Q9NHC3 0.438
worm Q21041 1 Q9NHC3 0.438

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.58
Domains Domains present in PDGFRB and CRKL:
Domains in PDGFRBDomains in CRKL
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR003598 Immunoglobulin C-2 type
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR013151 Immunoglobulin.
IPR001452 SH3
IPR000980 SH2 motif
IPR011511 SH3_2.

The Chi square scores for co-occurrence of domains that are present in PDGFRB and CRKL are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR008266 Tyrosine protein kinase, active site IPR001452 SH3 164.706
IPR001824 Receptor tyrosine kinase, class III IPR000980 SH2 motif 101.074
IPR001245 Tyrosine protein kinase IPR001452 SH3 100.857
IPR007110 Immunoglobulin-like IPR000980 SH2 motif 94.9752
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR003599 Immunoglobulin subtype IPR000980 SH2 motif 66.4833
IPR003598 Immunoglobulin C-2 type IPR000980 SH2 motif 64.7072
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000980 SH2 motif 49.095
IPR013151 Immunoglobulin. IPR000980 SH2 motif 36.9251
IPR001824 Receptor tyrosine kinase, class III IPR001452 SH3 32.2626
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR003598 Immunoglobulin C-2 type IPR001452 SH3 26.0449
IPR003599 Immunoglobulin subtype IPR001452 SH3 22.2905
IPR011009 Protein kinase-like IPR001452 SH3 20.4416
IPR007110 Immunoglobulin-like IPR001452 SH3 20.3228
IPR013151 Immunoglobulin. IPR001452 SH3 14.5395
IPR008266 Tyrosine protein kinase, active site IPR011511 SH3_2. 10.9904
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR001452 SH3 8.64336
IPR001245 Tyrosine protein kinase IPR011511 SH3_2. 4.28273
IPR007110 Immunoglobulin-like IPR011511 SH3_2. 0.657737
IPR000719 Protein kinase IPR011511 SH3_2. 0.0847071
IPR003598 Immunoglobulin C-2 type IPR011511 SH3_2. 0.0499293
IPR003599 Immunoglobulin subtype IPR011511 SH3_2. 0.0216579
IPR011009 Protein kinase-like IPR011511 SH3_2. 0.00500251

The background colour of the table refers to:

  • Blue Domain is only present in PDGFRB
  • Yellow Domain is only present in CRKL
  • Green Domain is present in both PDGFRB and CRKL

 0.980
Post-translational Modifications

Protein: PDGFRB

PTMResidueReference
Dephosphorylation 562 PubMed, HPRD
Dephosphorylation 579 PubMed, HPRD
Dephosphorylation 740 PubMed, HPRD
Dephosphorylation 751 PubMed, HPRD
Dephosphorylation 771 PubMed, HPRD
Dephosphorylation 857 PubMed, HPRD
Dephosphorylation 1009 PubMed, HPRD
Dephosphorylation 1021 PubMed, HPRD
Phosphorylation 579 PubMed, HPRD
Phosphorylation 581 PubMed, HPRD
Phosphorylation 716 PubMed, HPRD
Phosphorylation 740 PubMed, HPRD
Phosphorylation 751 PubMed, HPRD
Phosphorylation 763 PubMed, HPRD
Phosphorylation 771 PubMed, HPRD
Phosphorylation 775 PubMed, HPRD
Phosphorylation 857 PubMed, HPRD
Phosphorylation 1009 PubMed, HPRD
Phosphorylation 1021 PubMed, HPRD
Phosphotyrosine 751 PubMed, HPRD
Phosphotyrosine 857 PubMed, HPRD

Protein: CRKL

PTMResidueReference
Phosphorylation 107 PubMed, HPRD
Phosphorylation 207 PubMed, HPRD
Phosphotyrosine 207 HPRD
Phosphotyrosine 251 HPRD
Localisation

Protein: PDGFRB

LocalisationReference
Plasma membrane HPRD

Protein: CRKL

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PDGFRB and CRKL that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PDGFRB andCRKL. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PDGFRB has 1323 interactors and CRKL has 1611 interactors of which there are 757 common interactors.

Common InteractorName of Common InteractorScore for PDGFRB-Interactor (?)Score for CRKL-Interactor (?)
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 1.01E3 1.17
NCK2 NCK2: Cytoplasmic protein NCK2 600.00 108.00
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 600.00 430.00
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 532.00 281.00
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 422.00 0.148
STAT5B STAT5B: Signal transducer and activator of transcription 5B 372.00 0.245
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 315.00 0.097
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 281.00 1.35
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 281.00 0.171
VAV1 VAV1, VAV: Proto-oncogene vav 281.00 0.275
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 277.00 1.07
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 277.00 0.874
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 265.00 0.046
STAT6 STAT6: Signal transducer and activator of transcription 6 250.00 132.00
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 250.00 0.275
HCK N/A 250.00 1.07
JAK2 JAK2: Tyrosine-protein kinase JAK2 250.00 1.78
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 232.00 46.90
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 183.00 600.00
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 147.00 7.56
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 137.00 0.064
GRAP GRAP: GRB2-related adapter protein 133.00 0.028
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 112.00 388.00
KIT KIT: Mast/stem cell growth factor receptor precursor 112.00 388.00
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 84.00 65.60
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 82.20 0.655
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 74.00 370.00
JUP JUP, CTNNG, DP3: Junction plakoglobin 37.90 0.054
SHC2 N/A 29.70 1.29
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 19.20 0.040
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 15.80 0.099
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 12.50 0.111
PRKCG PRKCG, PKCG: Protein kinase C gamma type 12.50 0.097
SHC4 SHC-transforming protein 4 2.58 1.07
LOC392481 N/A 2.58 1.07
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 1.13 1.98
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 0.165
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.980 1.17
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.980 0.148
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 0.165
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 0.165
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.916 0.583
BMX N/A 0.902 0.775
STAT3 0.878 0.148
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.808 1.07
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 0.731 1.20
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.731 0.191
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.731 0.975
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 1.07
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.654 2.94
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.654 0.191
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.654 2.94
SYK SYK: Tyrosine-protein kinase SYK 0.654 1.78
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.191
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.644 1.35
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.644 0.152
JAK1 0.644 1.78
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.051
CRK CRK: Proto-oncogene C-crk 0.617 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.051
GRB10 N/A 0.617 0.051
APS SH2B2, APS: SH2B adapter protein 2 0.586 0.136
LYN LYN: Tyrosine-protein kinase Lyn 0.586 1.78
CSK CSK: Tyrosine-protein kinase CSK 0.586 2.94
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.581 0.251
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.581 0.859
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.581 1.98
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.581 0.191
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.046
RIN1 RIN1: Ras and Rab interactor 1 0.520 0.136
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.520 1.35
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.372 0.064
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.360 0.166
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.081
STAT2 STAT2: Signal transducer and activator of transcription 2 0.320 0.126
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.318 0.181
STAT4 STAT4: Signal transducer and activator of transcription 4 0.286 0.090
TNC TNC, HXB: Tenascin precursor 0.275 0.058
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.275 0.065
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.251 0.581
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.251 0.058
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.251 0.0727
VWF VWF, F8VWF: von Willebrand factor precursor 0.245 0.041
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.245 0.0308
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.233 0.058
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.225 0.065
SFRP1 CDNA FLJ45402 fis, clone BRHIP3029409, moderately similar to Homo sapiens secret 0.225 0.029
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.217 0.027
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.217 0.027
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.217 0.027
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.217 0.027
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.202 0.041
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.202 0.041
CNN3 CNN3: Calponin-3 0.202 0.088
GHR GHR: Growth hormone receptor precursor 0.191 0.100
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.191 0.0727
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.065
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.181 0.041
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.181 0.031
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.181 0.046
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.181 0.041
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.181 0.088
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.171 0.078
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.171 0.577
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.166 0.041
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
KIR3DL1 N/A 0.165 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
FN1 N/A 0.165 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.098
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.098
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.878
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.152 0.519
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.152 0.065
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.152 0.081
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.152 0.100
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.152 0.100
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.152 0.065
DAB2 DAB2, DOC2: Disabled homolog 2 0.148 0.111
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.098
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.098
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.878
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.098
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.878
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.098
BSG N/A 0.148 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 0.098
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.878
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.098
ATRN N/A 0.148 0.044
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.098
SOCS2 SOCS2, CIS2, SSI2, STATI2: Suppressor of cytokine signaling 2 0.145 0.036
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.143 0.028
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.136 0.655
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.136 0.577
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.136 0.577
INSR INSR: Insulin receptor precursor 0.136 277.00
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.136 0.577
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.136 0.577
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.129 0.402
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.129 0.041
FYN N/A 0.129 0.402
VAV3 VAV3: Protein vav-3 0.128 0.028
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.127 0.032
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.126 0.191
IRS1 IRS1: Insulin receptor substrate 1 0.126 0.098
CTTN CTTN, EMS1: Src substrate cortactin 0.126 2.77
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.125 0.036
PRLR PRLR: Prolactin receptor precursor 0.123 0.0727
EGF EGF: Pro-epidermal growth factor precursor 0.123 0.065
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.123 0.072
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.123 0.081
GPA33 GPA33: Cell surface A33 antigen precursor 0.123 0.072
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.123 0.113
MET MET: Hepatocyte growth factor receptor precursor 0.123 0.581
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.123 0.065
PVR PVR, PVS: Poliovirus receptor precursor 0.123 0.065
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.072
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.123 0.081
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.123 0.126
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.123 0.0727
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.123 0.081
F3 F3: Tissue factor precursor 0.123 0.072
RIN3 N/A 0.115 0.036
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.114 0.029
CHP CHP: Calcium-binding protein p22 0.113 0.054
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.113 0.097
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.112 0.044
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.111 0.655
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.111 277.00
MBTPS2 MBTPS2, S2P: Membrane-bound transcription factor site-2 protease 0.111 0.033
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.111 0.058
NEO1 NEO1, NGN: Neogenin precursor 0.111 0.065
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.111 0.577
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.110 0.166
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.110 0.274
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.110 0.126
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.110 0.166
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.110 0.274
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.110 0.036
SORL1 SORL1: Sortilin-related receptor precursor 0.110 0.148
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.110 0.166
LILRB1 N/A 0.110 0.126
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.110 0.126
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.109 0.047
NF2 NF2, SCH: Merlin 0.109 0.165
PPEF1 N/A 0.109 0.052
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.083
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.148
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.052
PSCD2 N/A 0.109 0.165
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.148
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.052
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
CNN2 CNN2: Calponin-2 0.109 0.148
ITGB4 N/A 0.109 0.081
IL9R IL9R: Interleukin-9 receptor precursor 0.109 0.100
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.109 0.072
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.109 0.586
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.100
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.109 0.126
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.109 0.100
EPOR EPOR: Erythropoietin receptor precursor 0.109 0.126
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.109 0.202
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.072
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.109 0.081
CD7 CD7: T-cell antigen CD7 precursor 0.109 0.126
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.166
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.109 0.100
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.109 0.0727
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.109 0.065
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.109 0.081
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.101 0.041
S100A3 S100A3, S100E: Protein S100-A3 0.100 0.031
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.099 0.181
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.098 0.191
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.098 0.126
CD69 CD69: Early activation antigen CD69 0.098 0.027
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.100
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.098 0.202
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.098 0.126
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.098 0.126
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.166
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.098 0.126
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.100
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.098 0.126
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.098 0.202
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.098 0.202
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.098 0.100
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.098 0.126
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.098 0.100
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.098 0.202
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.098 0.126
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.098 0.126
PTPRZ1 N/A 0.098 0.064
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.047
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.148
ELMO1 N/A 0.098 0.148
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.17
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.047
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.148
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.148
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.148
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.098 0.025
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.148
SNX3 N/A 0.098 0.075
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.148
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.047
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.098 0.025
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.148
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.148
ARHGEF7 N/A 0.098 0.148
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.148
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.148
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.483
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.148
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.148
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.047
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.062
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.098 0.047
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 250.00
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.097 0.577
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.097 0.577
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.113
DCC DCC: Netrin receptor DCC precursor 0.097 0.064
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.096 0.0453
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.096 0.0453
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.096 0.0333
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.090 5.88
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.090 0.111
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.090 0.088
MYL3 MYL3: Myosin light polypeptide 3 0.090 0.0308
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 0.097
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.088 0.808
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.088 0.064
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.088 0.113
ITGB7 ITGB7: Integrin beta-7 precursor 0.088 0.0818
CRLF3 N/A 0.088 0.274
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.086 0.026
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.086 1.37
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.049
EDA N/A 0.083 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.109
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.083 0.109
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.109
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.109
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 0.859
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.081 0.123
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.081 0.045
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.081 0.048
CSH2 GH1: Somatotropin precursor 0.081 0.025
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.081 0.048
S100A7 S100A7, PSOR1: Protein S100-A7 0.081 0.034
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.081 0.031
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.051
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.081 0.045
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.081 0.191
SPTAN1 N/A 0.081 0.109
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0782 0.034
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.148
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.044
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.044
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.098
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.073 0.111
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.073 0.043
RASA3 RASA3: Ras GTPase-activating protein 3 0.073 0.171
RDX RDX: Radixin 0.073 0.171
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.073 0.028
PLD1 PLD1: Phospholipase D1 0.073 0.171
SORBS3 SORBS3, SCAM1: Vinexin 0.073 0.111
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.073 0.054
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.073 0.071
PLD2 PLD2: Phospholipase D2 0.073 0.171
TTN N/A 0.073 0.097
DLG2 DLG2: Disks large homolog 2 0.073 0.041
TST TST: Thiosulfate sulfurtransferase 0.073 0.035
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.073 0.097
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.073 0.031
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.073 0.088
TLN2 TLN2: Uncharacterized protein TLN2 0.073 0.088
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.0727 0.251
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.0727 0.233
ROCK1 ROCK1: Rho-associated protein kinase 1 0.0727 0.251
IPO7 IPO7: Uncharacterized protein IPO7 0.0727 0.052
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.0727 0.191
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.098
S100B S100B: Protein S100-B 0.072 0.034
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.072 0.191
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.111
GRLF1 N/A 0.072 0.062
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.109
IRS2 IRS2: Insulin receptor substrate 2 0.072 0.123
GAB1 GAB1: GRB2-associated-binding protein 1 0.072 0.152
CETN1 CETN1, CEN1, CETN: Centrin-1 0.0688 0.036
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.065 0.275
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.065 0.275
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.065 14.60
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.065 0.225
LCP1 LCP1, PLS2: Plastin-2 0.065 0.118
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.065 0.225
CXorf9 N/A 0.065 0.275
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.065 0.171
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.065 0.372
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.065 0.087
GMIP GMIP: GEM-interacting protein 0.065 0.114
PSCD4 PSCD4, CYT4: Cytohesin-4 0.065 0.225
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.065 14.60
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.065 0.275
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.065 0.225
CD2AP CD2AP: CD2-associated protein 0.065 0.372
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.065 0.171
FNBP1 N/A 0.065 10.60
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.191
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.065 0.031
GAB2 N/A 0.065 0.191
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.065 0.251
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.065 0.048
VASP VASP: Vasodilator-stimulated phosphoprotein 0.065 0.251
SNCB SNCB: Beta-synuclein 0.065 0.034
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.065 0.0308
CSPG2 N/A 0.065 0.051
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.065 0.225
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.065 0.103
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.065 0.191
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.065 0.191
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.064 0.037
STAM2 STAM2: Signal transducing adapter molecule 2 0.064 0.111
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.064 0.225
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.064 0.043
TLN1 TLN1: Uncharacterized protein TLN1 0.064 0.225
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.064 0.099
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.046
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.361
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.064 0.111
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.064 0.037
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.064 0.171
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.064 0.088
VIL2 N/A 0.064 0.225
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.035
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.064 0.171
DAB1 DAB1: Disabled homolog 1 0.064 0.136
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.063 0.065
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.062 0.081
HPN HPN, TMPRSS1: Serine protease hepsin 0.062 0.029
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.062 0.032
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.098
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.062 0.036
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.098
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.061 0.046
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.060 0.115
CNN1 CNN1: Calponin-1 0.059 0.0273
THOP1 THOP1: Thimet oligopeptidase 0.058 0.046
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.058 0.097
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.058 0.171
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.058 0.225
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.058 0.136
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.058 0.275
PSD TYL: TYL protein 0.058 0.097
MSN MSN: Moesin 0.058 0.275
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.058 0.225
DOK1 DOK1: Docking protein 1 0.058 0.225
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.058 0.275
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.058 0.139
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.058 0.114
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.058 0.088
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.058 0.171
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.058 0.372
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.058 0.307
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.056 0.029
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.056 0.090
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.056 0.051
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.056 0.113
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.056 0.166
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.056 0.126
ATP2B1 N/A 0.056 0.037
CCR5 CCR5: CCR5 receptor (Fragment) 0.056 0.100
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.055 0.072
FADD FADD, MORT1: Protein FADD 0.055 0.036
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.055 0.032
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.055 0.065
CD44 N/A 0.055 0.061
SDC4 SDC4: Syndecan-4 precursor 0.054 0.026
STMN1 STMN1, LAP18, OP18: Stathmin 0.052 0.029
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.052 0.087
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.052 0.225
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.052 0.054
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.052 0.372
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.046
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
RAPH1 N/A 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
C9orf88 N/A 0.051 0.051
PTPRA N/A 0.051 0.051
NCAM1 N/A 0.051 0.051
IGHG1 N/A 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
MARK2 N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
UBAP2L N/A 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
IGHM N/A 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.046
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
HLA-A N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
IGHD N/A 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
TP73 TP73, P73: Tumor protein p73 0.051 0.081
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.051 0.081
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.051 0.081
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.051 0.171
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.051 0.097
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.051 0.097
MT3 MT3: Metallothionein-3 0.049 0.037
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.049 0.100
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.166
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.049 0.032
TSC2 TSC2, TSC4: Tuberin 0.049 0.025
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
MAPK15 N/A 0.049 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.028
MAP2K5 N/A 0.049 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
MYO18A 0.049 0.075
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.028
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.048 0.037
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.047 0.0338
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.098
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.046 0.051
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
FLT4 VEGFR3 long form 0.046 0.553
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.553
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
LMO7 N/A 0.046 0.046
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 22.10
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.046 0.113
SOS1 SOS1: Son of sevenless homolog 1 0.046 0.148
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.046 0.0446
PLEK PLEK, P47: Pleckstrin 0.046 0.202
CENTA1 CENTA1: Centaurin-alpha 1 0.046 0.063
CDKL5 N/A 0.0453 0.098
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.0453 0.088
RYR2 RYR2: Ryanodine receptor 2 0.045 0.025
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.044 0.051
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.044 0.372
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.171
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.044 0.148
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.025
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.044 0.148
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.044 0.148
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.044 0.148
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.075
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.044 0.025
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.075
NIPBL N/A 0.044 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.044 0.148
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.041 0.245
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.041 0.0818
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.041 0.304
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.041 0.081
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.073
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.041 0.225
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.041 0.099
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.041 0.225
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.041 0.037
MYO3A MYO3A: Myosin IIIA 0.041 0.088
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.041 0.162
MYH9 MYH9: Myosin-9 0.041 0.067
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.041 0.090
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
COTL1 COTL1, CLP: Coactosin-like protein 0.04 0.025
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.083
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.050
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.039 0.046
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.0263
SDC1 SDC1, SDC: Syndecan-1 precursor 0.039 0.037
GJA5 GJA5: Gap junction alpha-5 protein 0.038 0.047
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.038 0.0338
CALCRL CALCRL, CGRPR: Calcitonin gene-related peptide type 1 receptor precursor 0.038 0.058
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.051
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.037 0.123
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.037 0.029
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.037 0.032
FLNA FLNA, FLN, FLN1: Filamin-A 0.037 0.032
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.037 0.073
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.037 0.073
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.036 0.0446
GSN GSN: Gelsolin precursor 0.036 0.047
CFL2 CFL2: Cofilin-2 0.036 0.025
SVIL SVIL: Supervillin 0.036 0.047
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.035 0.058
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.073
ANXA3 ANXA3, ANX3: Annexin A3 0.034 0.030
TNN TNN: Tenascin-N precursor 0.034 0.034
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.0338 0.0338
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.0338 0.059
PKD1 PKD1: Polycystin-1 precursor 0.0338 0.047
MAL2 MAL2: Protein MAL2 0.034 0.034
HDLBP HDLBP, HBP, VGL: Vigilin 0.033 0.086
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.033 0.044
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.033 0.097
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.033 0.225
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.099
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.033 0.111
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.033 0.097
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.033 0.088
DYRK3 N/A 0.033 0.097
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.033 0.097
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.033 0.171
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.033 0.111
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.033 0.416
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.033 0.132
HD HD, IT15: Huntingtin 0.033 0.210
FUBP1 N/A 0.033 0.260
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.033 0.251
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.033 0.307
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.033 0.087
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.033 0.275
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.033 0.052
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.033 0.275
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.033 0.245
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.033 0.181
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.033 0.181
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.032 0.0425
CDK6 CDK6: Cell division protein kinase 6 0.032 0.171
PRKAA1 N/A 0.032 0.152
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.032 0.123
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.052
GAS2 GAS2: Growth arrest-specific protein 2 0.032 0.032
WEE1 WEE1: Wee1-like protein kinase 0.032 0.275
STK16 N/A 0.032 0.251
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.032 0.152
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.251
COBL N/A 0.032 0.098
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.191
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.032 0.026
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.0308 0.064
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.0308 0.064
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.034
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.030 0.034
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.030 0.053
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.030 0.098
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.036
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.030 0.098
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.098
DBN1 DBN1, D0S117E: Drebrin 0.030 0.026
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.030 0.058
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.029 0.233
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.029 0.078
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.029 0.063
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.029 0.233
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.029 0.129
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.029 0.372
HSP90AA1 Hsp89-alpha-delta-N 0.029 0.063
STK10 STK10: Uncharacterized protein STK10 0.029 0.275
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.461
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.029 0.040
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.275
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.029 0.078
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.029 0.078
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.171
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.029 0.078
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.029 0.069
WASPIP N/A 0.029 14.60
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.029 0.275
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.029 0.225
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.029 0.275
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.029 0.372
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.225
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.029 0.063
THOC1 THOC1, HPR1: THO complex subunit 1 0.029 0.046
ATM ATM: Serine-protein kinase ATM 0.029 0.225
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.029 0.078
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.029 0.063
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.029 0.029
CTPS CTPS: CTP synthase 1 0.029 0.063
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.029 0.372
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.029 0.461
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.029 0.152
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.029 0.046
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.029 0.127
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.029 0.275
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.029 0.171
CDK4 CDK4: Cell division protein kinase 4 0.029 0.372
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.029 0.111
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.029 0.029
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.029 0.136
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.029 0.275
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.029 0.029
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.111
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.038
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.058
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.049
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.049
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.028 0.058
PMP2 PMP2: Myelin P2 protein 0.027 0.044
FGFR2 N/A 0.027 0.217
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
B2M B2M, CDABP0092, HDCMA22P: Beta-2-microglobulin precursor [Contains: Beta-2-micro 0.026 0.027
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.026 0.275
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.026 0.049
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.026 0.063
FLII FLII, FLIL: Protein flightless-1 homolog 0.026 0.071
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.026 0.171
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.026 0.275
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.026 0.111
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.026 0.078
CDK5 CDK5: Cell division protein kinase 5 0.026 0.136
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.026 0.111
CDK2 CDK2: Cell division protein kinase 2 0.026 0.372
CD6 CD6: T-cell differentiation antigen CD6 precursor 0.026 0.035
CDK7 CDK7, MO15: Cell division protein kinase 7 0.026 0.275
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.026 0.275
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.026 0.097
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.026 0.275
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.026 0.038
RPS6KB1 N/A 0.026 0.372
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.026 0.114
SYMPK SYMPK, SPK: Symplekin 0.026 0.029
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.225
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.026 0.046
FES N/A 0.0258 0.0258
ETS2 ETS2: Protein C-ets-2 0.025 0.100
TOM1L1 TOM1L1, SRCASM: TOM1-like protein 1 0.025 0.030
SCML2 SCML2: Sex comb on midleg-like protein 2 0.025 0.065
OCLN OCLN: Occludin 0.025 0.025
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.098
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.044
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.044
0.572
Total Score 1.22E5