PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between ACTG1 and ACTB

The interaction score between ACTG1 and ACTB is 4.27E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between ACTG1 and ACTB = 0.87

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

0.027

Orthology

Organism	ACTG1 Orthologue		ACTB Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
human	IPI00008603	0.452	IPI00025416	0.452
human	IPI00021440	1	IPI00025416	0.452	Other Get References From PubMed
human	IPI00025416	0.452	IPI00025416	0.452
human	IPI00023006	0.435	IPI00025416	0.452
human	IPI00021428	0.403	IPI00025416	0.452
human	IPI00003269	0.238	IPI00025416	0.452
human	IPI00008603	0.452	IPI00023006	0.435
human	IPI00021440	1	IPI00023006	0.435
human	IPI00025416	0.452	IPI00023006	0.435
human	IPI00023006	0.435	IPI00023006	0.435
human	IPI00021428	0.403	IPI00023006	0.435
human	IPI00003269	0.238	IPI00023006	0.435
human	IPI00008603	0.452	IPI00021428	0.403
human	IPI00021440	1	IPI00021428	0.403
human	IPI00025416	0.452	IPI00021428	0.403
human	IPI00023006	0.435	IPI00021428	0.403
human	IPI00021428	0.403	IPI00021428	0.403	Y2H InVitro Get References From PubMed
human	IPI00003269	0.238	IPI00021428	0.403
human	IPI00008603	0.452	IPI00003269	0.238
human	IPI00021440	1	IPI00003269	0.238
human	IPI00025416	0.452	IPI00003269	0.238
human	IPI00023006	0.435	IPI00003269	0.238
human	IPI00021428	0.403	IPI00003269	0.238
human	IPI00003269	0.238	IPI00003269	0.238
bakers yeast	YFL039C	1	YFL039C	1	Y2H Get References From PubMed
fly	P02572	0.917	P02572	0.917

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

3.01

Domains

Domains present in ACTG1 and ACTB:

Domains in ACTG1

Domains in ACTB

IPR004000	Actin/actin-like
IPR004001	Actin

IPR004000	Actin/actin-like
IPR004001	Actin

The Chi square scores for co-occurrence of domains that are present in ACTG1 and ACTB are listed below.

Domain 1		Domain 2		Chi Square
IPR004000	Actin/actin-like	IPR004001	Actin	3.7059
IPR004000	Actin/actin-like	IPR004000	Actin/actin-like	2.94802

The background colour of the table refers to:

Blue Domain is only present in ACTG1
Yellow Domain is only present in ACTB
Green Domain is present in both ACTG1 and ACTB

0.014

Post-translational Modifications

Protein: ACTG1

PTM	Residue	Reference
N-acetylaspartate	2	PubMed, HPRD
Phosphotyrosine	166	HPRD
Phosphotyrosine	218	HPRD
Phosphotyrosine	294	HPRD

Protein: ACTB

PTM	Residue	Reference
N-acetylglutamate	2	PubMed, HPRD

Localisation

Protein: ACTG1

Localisation	Reference
Golgi	HPRD
Plasma membrane	HPRD
Nucleolus	HPRD
Cytoplasm	HPRD
Cytoskeleton	HPRD

Protein: ACTB

Localisation	Reference
Cytoplasm	HPRD
Cytoskeleton	HPRD

Transitive Score

The common interactors between ACTG1 and ACTB that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between ACTG1 andACTB. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , ACTG1 has 1176 interactors and ACTB has 308 interactors of which there are 297 common interactors.

Common Interactor	Name of Common Interactor	Score for ACTG1-Interactor (?)	Score for ACTB-Interactor (?)
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	1.02E3	346.00
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	621.00	346.00
WAS	WAS, IMD2: Wiskott-Aldrich syndrome protein	202.00	41.20
CFL2	CFL2: Cofilin-2	199.00	67.20
DSTN	DSTN, ACTDP, DSN: Destrin	183.00	77.60
GSN	GSN: Gelsolin precursor	170.00	24.00
PLD2	PLD2: Phospholipase D2	157.00	22.10
WASL	WASL: Neural Wiskott-Aldrich syndrome protein	131.00	44.20
WASPIP	N/A	122.00	33.3
CFL1	CFL1, CFL: Cofilin-1	122.00	41.20
EEF1A1	EEF1A1: Elongation factor 1-alpha	73.00	5.97
RAC2	RAC2: Ras-related C3 botulinum toxin substrate 2 precursor	62.00	3.30
CORO1C	CORO1C, CRNN4: Coronin-1C	53.80	12.50
IQGAP1	IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1	40.60	13.60
LCP1	LCP1, PLS2: Plastin-2	40.60	8.28
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	20.60	3.61
DIAPH1	Diaphanous 1	20.60	3.61
AVIL	AVIL: Advillin	16.30	6.81
MYH9	MYH9: Myosin-9	16.10	10.80
MYO9A	MYO9A: Myosin-IXA	13.20	13.20
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	13.00	5.30
CAP1	CAP1, CAP: Adenylyl cyclase-associated protein 1	12.60	2.39
TPM3	TPM3: Tropomyosin alpha-3 chain	12.20	0.845
PTK9	TWF1, PTK9: Twinfilin-1	12.20	0.845
DMD	DMD: Dystrophin	11.50	11.50
PRKCA	PRKCA, PKCA, PRKACA: Protein kinase C alpha type	7.92	1.38
CNN2	CNN2: Calponin-2	7.88	2.65
PRKCG	PRKCG, PKCG: Protein kinase C gamma type	7.14	1.38
WRNIP1	WRNIP1, WHIP: ATPase WRNIP1	6.64	1.16
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	6.31	2.00
CTTN	CTTN, EMS1: Src substrate cortactin	5.88	1.98
TAGLN	TAGLN, SM22, WS3-10: Transgelin	5.88	2.44
CNN3	CNN3: Calponin-3	4.67	1.74
ACTA2	ACTA2, ACTSA, GIG46, ACTVS: Actin, aortic smooth muscle	4.28	4.28
MYO1F	MYO1F: Myosin-If	3.96	2.36
MYH10	MYH10: Myosin-10	3.71	3.71
RPLP2	RPLP2, D11S2243E, RPP2: 60S acidic ribosomal protein P2	3.59	0.680
CAPN9	CAPN9, NCL4: Calpain-9	3.52	3.52
HTATIP	N/A	3.39	0.795
NULL	N/A	3.01	3.01
MAP1B	MAP1B: Microtubule-associated protein 1B	2.98	0.264
NULL	N/A	2.58	1.07
HSP90AA1	Hsp89-alpha-delta-N	2.47	0.354
WIRE	WIPF2, WICH, PP10631, WIRE: WAS/WASL-interacting protein family member 2	2.36	1.93
FGD1	FGD1, FGDY, ZFYVE3: FYVE, RhoGEF and PH domain-containing protein 1	2.09	2.09
TRAF1	TRAF1, EBI6: TNF receptor-associated factor 1	1.94	1.94
TMSB4X	TMSB4X, TB4X, THYB4, TMSB4: Thymosin beta-4	1.81	0.613
CNN1	CNN1: Calponin-1	1.45	0.112
PLS1	PLS1: Plastin-1	1.27	1.27
TRAF5	TRAF5, RNF84: TNF receptor-associated factor 5	1.19	0.977
TRAF2	N/A	1.07	1.07
MYH4	MYH4: Myosin-4	1.00	1.00
TRAF6	TRAF6, RNF85: TNF receptor-associated factor 6	0.977	0.741
CFDP1	CFDP1, BCNT: Craniofacial development protein 1	0.902	1.10
EEF1A2	EEF1A2, EEF1AL, STN: Elongation factor 1-alpha 2	0.890	0.155
TAGLN3	TAGLN3, NP25: Transgelin-3	0.849	0.674
STAT6	STAT6: Signal transducer and activator of transcription 6	0.822	0.075
MAPRE1	MAPRE1: Microtubule-associated protein RP/EB family member 1	0.763	0.257
FLII	FLII, FLIL: Protein flightless-1 homolog	0.763	0.257
VAV1	VAV1, VAV: Proto-oncogene vav	0.763	0.156
PRKCH	PRKCH, PKCL, PRKCL: Protein kinase C eta type	0.741	0.741
MYO5B	MYO5B, KIAA1119: Myosin-Vb	0.715	0.715
MYH14	MYH14, KIAA2034, FP17425: Myosin-14	0.674	0.674
RUVBL1	RUVBL1, NMP238, TIP49, TIP49A: RuvB-like 1	0.657	0.657
EIF1AX	EIF1AX, EIF1A, EIF4C: Eukaryotic translation initiation factor 1A, X-chromosomal	0.657	0.657
FSCN2	FSCN2: Fascin-2	0.638	0.638
IQGAP3	IQGAP3: Uncharacterized protein IQGAP3	0.593	0.593
PLS3	Plastin 3 variant (Fragment)	0.593	0.593
D2HGDH	D2HGDH, D2HGD: D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor	0.593	0.593
DMAP1	DMAP1, hCG_25204: Uncharacterized protein DMAP1	0.593	0.593
SRCAP	KIAA0309: KIAA0309 protein (Fragment)	0.593	0.593
PFN4	PFN4: Profilin-4	0.593	0.593
HSPCB		0.593	0.593
NULL	N/A	0.593	0.593
INOC1	INOC1, KIAA1259: Putative DNA helicase INO80 complex homolog 1	0.593	0.593
NEDD4L	N/A	0.593	0.593
MYO1E	N/A	0.593	0.593
CAP2	CAP2: Adenylyl cyclase-associated protein 2	0.593	0.593
PAK2	PAK2: Serine/threonine-protein kinase PAK 2	0.593	0.593
CSTF3	CSTF3: Cleavage stimulation factor 77 kDa subunit	0.538	0.657
ACTR3	ACTR3, ARP3: Actin-related protein 3	0.515	0.065
FLNA	FLNA, FLN, FLN1: Filamin-A	0.515	0.174
RAC3	RAC3: Ras-related C3 botulinum toxin substrate 3 precursor	0.479	0.592
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.461	0.156
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.461	0.257
SNX17	SNX17, KIAA0064: Sorting nexin-17	0.461	0.156
SEC24B	SEC24B: Protein transport protein Sec24B	0.461	0.156
ARHGEF6	ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6	0.461	0.156
HIP1R	HIP1R, HIP12, KIAA0655: Huntingtin-interacting protein 1-related protein	0.443	0.443
SUMO2	SUMO2, SMT3B, SMT3H2: Small ubiquitin-related modifier 2 precursor	0.442	0.442
MVP	MVP, LRP: Major vault protein	0.430	0.084
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.416	0.103
SUMO1	SUMO1, SMT3C, OK/SW-cl.43, SMT3H3, UBL1: Small ubiquitin-related modifier 1 prec	0.412	0.412
EIF1AY	EIF1AY: Eukaryotic translation initiation factor 1A, Y-chromosomal	0.408	0.233
MSN	MSN: Moesin	0.385	0.075
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.385	0.075
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.385	0.045
EPRS	EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes:	0.372	0.126
CCT8	CCT8: Uncharacterized protein CCT8	0.372	0.126
H2AFZ	H2AFZ, H2AZ: Histone H2A.Z	0.364	0.494
MCM5	MCM5, CDC46: DNA replication licensing factor MCM5	0.364	0.364
ARMC3	N/A	0.354	0.354
RUVBL2	RUVBL2, TIP48, CGI-46, TIP49B: RuvB-like 2	0.326	0.408
RHOA	RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor	0.307	0.054
NCF1	Neutrophil cytosolic factor 1 variant (Fragment)	0.307	0.085
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.304	0.123
TMSB10	TMSB10, PTMB10, THYB10: Thymosin beta-10	0.293	0.293
CLIC1	CLIC1, NCC27: Chloride intracellular channel protein 1	0.276	0.048
CCT6A	CCT6A, CCT6, CCTZ: T-complex protein 1 subunit zeta	0.275	0.126
TCP1	CCT1, CCTA, TCP1: T-complex protein 1 subunit alpha	0.275	0.044
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.275	0.126
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.275	0.093
SGK3	SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3	0.275	0.093
LASP1	LASP1, MLN50: LIM and SH3 domain protein 1	0.269	0.0278
HMGCS1	HMGCS1, HMGCS: Hydroxymethylglutaryl-CoA synthase, cytoplasmic	0.264	0.326
IMPACT	IMPACT: IMPACT protein	0.264	0.264
SH3BP2	SH3BP2: Uncharacterized protein SH3BP2	0.260	0.041
CAPNS1	CAPNS1, CAPN4, CAPNS: Calpain small subunit 1	0.260	0.042
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.241	0.065
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.233	0.045
PSCD4	PSCD4, CYT4: Cytohesin-4	0.233	0.037
EHD1	EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1	0.233	0.037
TLN1	TLN1: Uncharacterized protein TLN1	0.233	0.037
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.233	0.037
CAPN2	CAPN2, CANPL2: Calpain-2 catalytic subunit precursor	0.233	0.045
JAK1		0.233	0.037
HCK	N/A	0.233	0.027
NCK1	NCK1, NCK: Cytoplasmic protein NCK1	0.233	0.045
DOK1	DOK1: Docking protein 1	0.233	0.045
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.233	0.027
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.227	0.032
YEATS4	YEATS4, GAS41: YEATS domain-containing protein 4	0.227	0.227
IQSEC1	IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein	0.225	0.046
FLNB	FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B	0.225	0.093
ACTN1	ACTN1: Alpha-actinin-1	0.225	0.076
MAPRE2	MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2	0.225	0.058
GMFB	GMFB: Glia maturation factor beta	0.225	0.058
HSPD1		0.225	0.076
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.210	0.030
VASP	VASP: Vasodilator-stimulated phosphoprotein	0.210	0.030
S100A9	S100A9, CAGB, CFAG, MRP14: Protein S100-A9	0.210	0.030
ROCK1	ROCK1: Rho-associated protein kinase 1	0.210	0.030
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.210	0.030
CORO1A	CORO1A, CORO1: Coronin-1A	0.203	0.123
LOC653066		0.196	0.196
IPI00018278	H2AFV, H2AV: Histone H2AV	0.196	0.196
ARFGAP1	ARFGAP1, ARF1GAP: ADP-ribosylation factor GTPase-activating protein 1	0.196	0.196
DLG4	DLG4, PSD95: Disks large homolog 4	0.189	0.189
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.188	0.037
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.188	0.045
ACTA1	ACTA1, ACTA: Actin, alpha skeletal muscle	0.172	0.152
MICAL-L1	MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1	0.171	0.076
ACTC	ACTC1, ACTC: Actin, alpha cardiac muscle 1	0.169	0.169
PPEF1	N/A	0.165	0.056
ZYX	ZYX: Zyxin	0.163	0.0354
LIMS1	N/A	0.163	0.044
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.160	0.160
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.157	0.037
WDR1	N/A	0.157	0.037
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.154	0.154
PLEK	PLEK, P47: Pleckstrin	0.153	0.035
ACTG2	ACTG2, ACTA3, ACTL3, ACTSG: Actin, gamma-enteric smooth muscle	0.152	0.169
DBN1	DBN1, D0S117E: Drebrin	0.152	0.085
ANAPC10	ANAPC10, APC10: Anaphase-promoting complex subunit 10	0.148	0.148
CD63	CD63, MLA1, TSPAN30: CD63 antigen	0.148	0.0735
COTL1	COTL1, CLP: Coactosin-like protein	0.148	0.050
ACTN4	ACTN4: Alpha-actinin-4	0.148	0.050
MYO18A		0.148	0.050
SPTBN1	SPTBN1, SPTB2: Spectrin beta chain, brain 1	0.148	0.050
SVIL	SVIL: Supervillin	0.148	0.050
SNX3	N/A	0.148	0.050
CXorf9	N/A	0.146	0.039
LPXN	LPXN, LDLP: Leupaxin	0.146	0.039
MYH3	MYH3: Myosin-3	0.143	0.143
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.139	0.037
ELMO2	ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2	0.139	0.027
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.139	0.037
CD2AP	CD2AP: CD2-associated protein	0.139	0.037
VIL2	N/A	0.139	0.027
OSBP	OSBP, OSBP1: Oxysterol-binding protein 1	0.139	0.037
MICAL1	MICAL1, MICAL, NICAL: NEDD9-interacting protein with calponin homology and LIM d	0.137	0.083
ITGB2	ITGB2, CD18, MFI7: Integrin beta-2 precursor	0.137	0.026
DUSP1	DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1	0.137	0.026
EHBP1	EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1	0.136	0.046
PLD1	PLD1: Phospholipase D1	0.136	0.046
WASF2	WASF2, WAVE2: Wiskott-Aldrich syndrome protein family member 2	0.123	0.074
SNX6	SNX6: Sorting nexin-6	0.123	0.123
GMFG	GMFG: Glia maturation factor gamma	0.123	0.074
NULL	LOC391257: LOC391257 protein	0.119	0.119
PAK1	N/A	0.119	0.119
NULL	N/A	0.119	0.119
HIP1		0.119	0.119
NULL	RP11-415H23.3-001: Elongation factor 1-alpha	0.119	0.119
MYO5A	N/A	0.119	0.119
NULL	N/A	0.119	0.119
NULL	Uncharacterized protein ENSP00000333488	0.119	0.119
NULL	N/A	0.119	0.119
MYH6	MYH6, MYHCA: Myosin-6	0.119	0.119
NULL	Uncharacterized protein ENSP00000334809	0.119	0.119
PAK3	N/A	0.119	0.119
MYH7		0.119	0.119
ING4	N/A	0.119	0.119
TPM1	DKFZp586K2222, TPM1, hCG_33495: Putative uncharacterized protein DKFZp586K2222	0.119	0.119
NULL	N/A	0.119	0.119
NULL	N/A	0.119	0.119
NULL	Uncharacterized protein ENSP00000328991 (Fragment)	0.119	0.119
TPM4	N/A	0.119	0.119
NULL	N/A	0.119	0.119
DKFZp686D0972	ACT: Actin-like protein (Fragment)	0.119	0.119
NULL	N/A	0.119	0.119
ITGB7	ITGB7: Integrin beta-7 precursor	0.111	0.026
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.111	0.046
COBL	N/A	0.110	0.037
DSP	DSP: Desmoplakin	0.109	0.044
TMSL8	TMSL8, TMSNB: NB thymosin beta	0.109	0.051
MYO3A	MYO3A: Myosin IIIA	0.099	0.026
PARVA	PARVA, MXRA2: Alpha-parvin	0.099	0.033
MCF2	MCF2, DBL: Proto-oncogene DBL	0.098	0.037
SPTAN1	N/A	0.098	0.033
VIL1	VIL1, VIL: Villin-1	0.097	0.033
MYO5C	MYO5C: Myosin-Vc	0.096	0.085
PSD	TYL: TYL protein	0.088	0.0296
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.086	0.040
MYH11	MYH11, KIAA0866: Myosin-11	0.085	0.085
MYH2	MYH2, MYHSA2: Myosin-2	0.085	0.085
MYH1	MYH1: Myosin-1	0.085	0.085
MYH8	MYH8: Myosin-8	0.085	0.085
CPNE1	CPNE1, CPN1: Copine-1	0.083	0.083
SNX11	SNX11: Sorting nexin-11	0.083	0.067
SSH1	SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1	0.0818	0.026
MRCL3	MRLC2, MLCB, RLC: Myosin regulatory light chain 2, nonsarcomeric	0.081	0.081
D2HGDH	N/A	0.08	0.08
MYH13	MYH13: Myosin-13	0.076	0.076
MYO9B	MYO9B, MYR5: Myosin-IXb	0.074	0.083
EIF3S10	EIF3S10, KIAA0139: Eukaryotic translation initiation factor 3 subunit 10	0.074	0.074
SNX1	SNX1: Sorting nexin-1	0.074	0.074
CORO1B	CORO1B: Coronin-1B	0.0732	0.099
PPL	PPL, KIAA0568: Periplakin	0.072	0.033
TPM2	N/A	0.071	0.078
MYH7B	MYH7B: Myosin, heavy chain 7B, cardiac muscle, beta	0.071	0.078
VILL	VILL: Villin-like protein	0.067	0.067
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.066	0.033
LRCH4	LRCH4, LRN, LRRN1, LRRN4: Leucine-rich repeat and calponin homology domain-conta	0.065	0.065
DNASE1L1	DNASE1L1, DNAS1L1, DNL1L: Deoxyribonuclease I-like 1 precursor	0.065	0.065
SNX5	SNX5: Sorting nexin-5	0.060	0.060
CCT5	CCT5, CCTE, KIAA0098: T-complex protein 1 subunit epsilon	0.060	0.060
CCT3	CCT3, CCTG, TRIC5: T-complex protein 1 subunit gamma	0.060	0.060
CPNE3	CPNE3, CPN3, KIAA0636: Copine-3	0.060	0.074
CORO2A	CORO2A, IR10, WDR2: Coronin-2A	0.053	0.053
SUMO3	SUMO3, SMT3A, SMT3H1: Small ubiquitin-related modifier 3 precursor	0.050	0.050
PARVB	PARVB, CGI-56: Beta-parvin	0.050	0.041
TTRAP	TTRAP, EAP2, AD-022: TRAF and TNF receptor-associated protein	0.047	0.053
CNOT6	CNOT6, CCR4, KIAA1194: CCR4-NOT transcription complex subunit 6	0.047	0.059
SEC23A	SEC23A: Protein transport protein Sec23A	0.044	0.060
CCT7	CCT7, CCTH, NIP7-1: T-complex protein 1 subunit eta	0.044	0.060
SEC23B	SEC23B: Protein transport protein Sec23B	0.044	0.060
SEC24D	SEC24D: SEC24 related gene family, member D	0.044	0.060
LMAN2	LMAN2, C5orf8: Vesicular integral-membrane protein VIP36 precursor	0.044	0.027
SCAP2	SKAP2, PRAP, RA70, SAPS, SCAP2, SKAP55R: Src kinase-associated phosphoprotein 2	0.042	0.0255
OSTF1	N/A	0.042	0.042
HMGCS2	HMGCS2: Hydroxymethylglutaryl-CoA synthase, mitochondrial precursor	0.0421	0.047
CORO2B	CORO2B, KIAA0925: Coronin-2B	0.0421	0.047
GAS2	GAS2: Growth arrest-specific protein 2	0.0416	0.0416
SNX4	SNX4: Sorting nexin-4	0.041	0.041
SWAP70	SWAP70, KIAA0640, HSPC321: Switch-associated protein 70	0.041	0.041
MKKS	MKKS: McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin	0.041	0.0308
ING1	ING1, RP11-8D7.1-004: Inhibitor of growth family, member 1	0.039	0.039
LOC402643	N/A	0.039	0.039
VAV3	VAV3: Protein vav-3	0.036	0.036
ING2	ING2, ING1L: Inhibitor of growth protein 2	0.0363	0.0455
ITGAE	ITGAE: Integrin alpha-E precursor	0.035	0.0286
CANX	CANX: Calnexin precursor	0.035	0.027
GCC2	GCC2, KIAA0336, RANBP2L4: GRIP and coiled-coil domain-containing protein 2	0.032	0.032
ARHGEF7	ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB: Rho guanine nucleotide exchange	0.0308	0.041
APEX2	APEX2, APE2, APEXL2, XTH2: DNA-(apurinic or apyrimidinic site) lyase 2	0.029	0.029
SCIN	SCIN, KIAA1905: Adseverin	0.028	0.028
MTSS1	N/A	0.028	0.028
ARPC4	actin related protein 2/3 complex subunit 4 isoform b	0.027	0.027
PSD3	N/A	0.027	0.027
RASGRF2	RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment)	0.027	0.027
TRIM54	TRIM54, MURF, MURF3, RNF30: Tripartite motif-containing protein 54	0.027	0.027
CPNE7	CPNE7: Copine-7	0.027	0.027
DMD	dystrophin: Dystrophin protein (Fragment)	0.027	0.027
PXK	PXK: PX domain-containing protein kinase-like protein	0.027	0.027
OSBPL9	N/A	0.027	0.027
TRIM49	TRIM49, RNF18: Tripartite motif-containing protein 49	0.027	0.027
DMD	N/A	0.027	0.027
SNX22	SNX22: Sorting nexin-22	0.027	0.027
PARVG	PARVG: Gamma-parvin	0.027	0.027
INVS	N/A	0.027	0.027
IQGAP3	IQGAP3: Ras GTPase-activating-like protein IQGAP3	0.027	0.027
RASGRF1	RASGRF1, CDC25: Guanine nucleotide-releasing protein	0.027	0.027
GAS2L3	GAS2L3: GAS2-like protein 3	0.027	0.027
SNX24	SNX24, SBBI31, UNQ654/PRO1284: Sorting nexin-24	0.027	0.027
SEC13L1	SEC13, D3S1231E, SEC13L1, SEC13R: Protein SEC13 homolog	0.027	0.027
PLEKHO1	PLEKHO1, CKIP1, OC120, HQ0024c: Pleckstrin homology domain-containing family O m	0.0255	0.0255
PDCD6	PDCD6, ALG2: Programmed cell death protein 6	0.0255	0.0255

0.572

Total Score

4.27E4