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Evidence of Interaction Between CCL17 and NMUR1

The interaction score between CCL17 and NMUR1 is 0.250.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between CCL17 and NMUR1 = 0.27

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 2.88E-3
Orthology N/A N/A
Domains Domains present in CCL17 and NMUR1:
Domains in CCL17Domains in NMUR1
IPR000827 Small chemokine, C-C subfamily
IPR001811 Small chemokine, interleukin-8 like
IPR000276 Rhodopsin-like GPCR superfamily
IPR005390 Neuromedin U receptor
IPR005391 NeuromedinU1.

The Chi square scores for co-occurrence of domains that are present in CCL17 and NMUR1 are listed below.

Domain 1Domain 2Chi Square
IPR000827 Small chemokine, C-C subfamily IPR000276 Rhodopsin-like GPCR superfamily 379.333
IPR001811 Small chemokine, interleukin-8 like IPR000276 Rhodopsin-like GPCR superfamily 356.918

The background colour of the table refers to:

  • Blue Domain is only present in CCL17
  • Yellow Domain is only present in NMUR1
  • Green Domain is present in both CCL17 and NMUR1

 0.217
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation

Protein: CCL17

LocalisationReference
Secreted HPRD

Protein: NMUR1

No localisation data was used in calculating likelihood of interaction
Transitive Score No Transitive data was used in the prediction of this interaction. N/A
Total Score 0.250