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Evidence of Interaction Between JAK2 and STAT1

The interaction score between JAK2 and STAT1 is 9.66E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismJAK2 OrthologueSTAT1 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00022353 0.245 IPI00030783 0.067
human IPI00219418 0.385 IPI00030783 0.067
human IPI00011633 0.316 IPI00030783 0.067
  • Other
  • InVivo

Get References From PubMed
human IPI00022353 0.245 IPI00103415 0.067
human IPI00219418 0.385 IPI00103415 0.067
human IPI00011633 0.316 IPI00103415 0.067

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 1.07
Domains Domains present in JAK2 and STAT1:
Domains in JAK2Domains in STAT1
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR000299 Band 4.1
IPR000980 SH2 motif
IPR009127 Janus kinase, JAK
IPR009129 Janus kinase 2, JAK2
IPR000980 SH2 motif
IPR001217 STAT protein
IPR011992 EF-Hand_type.
IPR012345 STAT_DNA_bd.

The Chi square scores for co-occurrence of domains that are present in JAK2 and STAT1 are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR009127 Janus kinase, JAK IPR000980 SH2 motif 59.5626
IPR000299 Band 4.1 IPR000980 SH2 motif 47.6792
IPR000980 SH2 motif IPR000980 SH2 motif 36.445
IPR008266 Tyrosine protein kinase, active site IPR001217 STAT protein 22.9582
IPR008266 Tyrosine protein kinase, active site IPR012345 STAT_DNA_bd. 22.9582
IPR009127 Janus kinase, JAK IPR012345 STAT_DNA_bd. 21.431
IPR009127 Janus kinase, JAK IPR001217 STAT protein 21.431
IPR000719 Protein kinase IPR011992 EF-Hand_type. 15.5567
IPR009129 Janus kinase 2, JAK2 IPR000980 SH2 motif 13.3485
IPR000980 SH2 motif IPR001217 STAT protein 12.56
IPR000980 SH2 motif IPR012345 STAT_DNA_bd. 12.56
IPR001245 Tyrosine protein kinase IPR012345 STAT_DNA_bd. 11.9355
IPR001245 Tyrosine protein kinase IPR001217 STAT protein 11.9355
IPR011009 Protein kinase-like IPR011992 EF-Hand_type. 9.34155
IPR000299 Band 4.1 IPR012345 STAT_DNA_bd. 6.45105
IPR000299 Band 4.1 IPR001217 STAT protein 6.45105
IPR001245 Tyrosine protein kinase IPR011992 EF-Hand_type. 6.38624
IPR000980 SH2 motif IPR011992 EF-Hand_type. 5.54712
IPR000719 Protein kinase IPR001217 STAT protein 2.68473
IPR000719 Protein kinase IPR012345 STAT_DNA_bd. 2.68473
IPR011009 Protein kinase-like IPR012345 STAT_DNA_bd. 1.35691
IPR011009 Protein kinase-like IPR001217 STAT protein 1.35691
IPR008266 Tyrosine protein kinase, active site IPR011992 EF-Hand_type. 1.24952
IPR009127 Janus kinase, JAK IPR011992 EF-Hand_type. 0.35214
IPR000299 Band 4.1 IPR011992 EF-Hand_type. 0.0138252

The background colour of the table refers to:

  • Blue Domain is only present in JAK2
  • Yellow Domain is only present in STAT1
  • Green Domain is present in both JAK2 and STAT1

 0.980
Post-translational Modifications

Protein: JAK2

PTMResidueReference
Dephosphorylation 1007 PubMed, HPRD
Dephosphorylation 1008 PubMed, HPRD
Phosphorylation 201 PubMed, HPRD
Phosphorylation 221 PubMed, HPRD
Phosphorylation 570 PubMed, HPRD
Phosphorylation 813 PubMed, HPRD
Phosphorylation 1007 PubMed, HPRD
Phosphorylation 1008 PubMed, HPRD

Protein: STAT1

PTMResidueReference
Dephosphorylation 701 PubMed, HPRD
Dephosphorylation 727 PubMed, HPRD
Methylation 31 PubMed, HPRD
Phosphorylation 701 PubMed, HPRD
Phosphorylation 727 PubMed, HPRD
Phosphoserine 727 HPRD
Phosphotyrosine 701 PubMed, HPRD
Sumoylation 703 PubMed, HPRD
Localisation

Protein: JAK2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: STAT1

LocalisationReference
Nucleus HPRD
Nucleolus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between JAK2 and STAT1 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between JAK2 andSTAT1. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , JAK2 has 1724 interactors and STAT1 has 1786 interactors of which there are 1143 common interactors.

Common InteractorName of Common InteractorScore for JAK2-Interactor (?)Score for STAT1-Interactor (?)
STAT6 STAT6: Signal transducer and activator of transcription 6 2.90E3 131.00
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 1.06E3 232.00
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 1.04E3 131.00
STAT5B STAT5B: Signal transducer and activator of transcription 5B 784.00 199.00
ZAP70 ZAP70: Uncharacterized protein ZAP70 650.00 422.00
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 563.00 0.878
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 370.00 422.00
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 333.00 0.878
INSR INSR: Insulin receptor precursor 277.00 0.483
PDGFRB PDGFRB: Beta-type platelet-derived growth factor receptor precursor 250.00 232.00
STAM2 STAM2: Signal transducing adapter molecule 2 82.20 0.098
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 53.10 0.098
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 46.90 29.60
LYN LYN: Tyrosine-protein kinase Lyn 6.73 0.878
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 6.03 0.878
HCK N/A 6.03 0.878
SYK SYK: Tyrosine-protein kinase SYK 6.03 0.980
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 6.03 0.980
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 4.07 0.109
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 3.64 0.980
VAV1 VAV1, VAV: Proto-oncogene vav 3.64 0.098
SLA SLA, SLAP, SLAP1: SRC-like-adapter 3.28 0.109
JAK1 2.94 0.980
CSK CSK: Tyrosine-protein kinase CSK 2.94 0.878
LCP2 LCP2: Lymphocyte cytosolic protein 2 2.46 0.165
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 2.17 0.098
BLNK BLNK, BASH, SLP65: B-cell linker protein 1.98 0.109
CRKL CRKL: Crk-like protein 1.78 46.90
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 1.50 0.109
SRC SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src 1.50 0.980
STAT2 STAT2: Signal transducer and activator of transcription 2 1.48 0.165
FLT3 FLT3, STK1: FL cytokine receptor precursor 1.48 0.483
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 1.35 0.878
NCK2 NCK2: Cytoplasmic protein NCK2 1.35 0.098
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 1.33 0.148
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 1.30 0.109
LNK SH2B3, LNK: SH2B adapter protein 3 1.30 0.109
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 1.30 0.980
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 1.30 0.109
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 1.30 0.980
STAT3 1.30 14.80
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 1.20 0.980
LILRB1 N/A 1.19 0.0688
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 1.17 0.109
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 1.17 0.878
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 1.17 0.980
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 1.17 0.098
TXK TXK, PTK4: Tyrosine-protein kinase TXK 1.07 0.980
RIN1 RIN1: Ras and Rab interactor 1 1.07 0.148
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 1.07 0.098
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.980 0.540
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.980 0.540
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.980 0.540
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.975 0.109
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.975 0.109
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 0.975 0.980
STAT4 STAT4: Signal transducer and activator of transcription 4 0.902 22.50
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.878 0.483
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.878 232.00
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.878 0.540
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.878 0.483
APS SH2B2, APS: SH2B adapter protein 2 0.874 0.098
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.872 0.980
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.859 1.30
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.859 0.980
BMX N/A 0.859 0.980
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.852 0.109
KIT KIT: Mast/stem cell growth factor receptor precursor 0.808 0.483
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 0.781 0.098
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.775 0.878
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.770 0.878
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.763 0.098
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.763 0.098
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.763 0.098
GMIP GMIP: GEM-interacting protein 0.763 0.044
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.763 0.148
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.763 0.098
PSCD4 PSCD4, CYT4: Cytohesin-4 0.763 0.098
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.655 0.483
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.655 0.148
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.654 0.483
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.654 0.540
GRB10 N/A 0.617 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.617 0.617
CRK CRK: Proto-oncogene C-crk 0.617 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.617 0.617
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.051
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.617 0.617
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.617 0.617
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.586 0.483
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 0.586 0.483
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.586 0.483
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.586 0.483
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.586 0.483
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.586 0.540
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.581 0.540
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.581 0.165
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.577 0.483
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.577 0.483
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.577 0.483
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 0.577 0.483
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.561 0.0688
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.561 0.0688
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.561 0.0688
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.046
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.553 0.553
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 0.553 0.046
FLT4 VEGFR3 long form 0.553 0.553
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.520 0.483
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.520 0.483
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.520 0.483
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 0.520 0.483
MET MET: Hepatocyte growth factor receptor precursor 0.519 0.540
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.515 0.049
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.515 0.165
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.515 0.165
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.515 0.165
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.503 0.148
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.503 0.148
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.503 0.062
FYN N/A 0.491 0.217
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.483 0.483
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.461 0.098
MSN MSN: Moesin 0.461 0.098
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.461 0.098
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.461 0.148
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.461 0.148
LCP1 LCP1, PLS2: Plastin-2 0.461 0.098
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.461 0.148
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.461 0.148
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.461 0.148
DOK1 DOK1: Docking protein 1 0.461 0.148
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.461 0.148
STK10 STK10: Uncharacterized protein STK10 0.461 0.148
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.461 0.148
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.461 0.148
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.416 0.109
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.416 0.109
ROCK1 ROCK1: Rho-associated protein kinase 1 0.416 0.165
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.416 0.165
IRS2 IRS2: Insulin receptor substrate 2 0.416 0.165
GAB2 N/A 0.416 0.165
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.416 0.109
VASP VASP: Vasodilator-stimulated phosphoprotein 0.416 0.109
WASPIP N/A 0.372 0.098
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.372 0.148
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.372 0.148
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.372 0.044
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.372 0.148
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.372 0.148
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.372 0.165
CXorf9 N/A 0.372 0.148
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.372 0.148
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.372 0.148
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.372 0.148
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.372 0.148
RPS6KB1 N/A 0.372 0.148
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.372 0.148
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.372 0.036
ALK ALK: ALK tyrosine kinase receptor precursor 0.361 0.483
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.347 0.187
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.340 0.0688
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.340 0.0688
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.340 0.0688
PLEK PLEK, P47: Pleckstrin 0.340 0.165
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.340 0.0688
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.340 0.0688
CRLF3 N/A 0.340 0.0688
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.340 0.0688
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.340 0.0688
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.307 0.165
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.307 0.165
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.307 0.165
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.307 0.04
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.307 0.165
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.305 0.217
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.304 0.025
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.304 0.148
LTK LTK, TYK1: Leukocyte tyrosine kinase receptor precursor 0.296 0.126
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.275 0.148
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.275 0.148
FNBP1 N/A 0.275 0.148
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.275 0.109
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.275 0.098
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.275 0.148
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.275 0.148
TLN1 TLN1: Uncharacterized protein TLN1 0.275 0.098
CD2AP CD2AP: CD2-associated protein 0.275 0.098
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.275 0.049
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.275 0.148
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.275 0.148
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.275 0.098
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.275 0.148
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.275 0.148
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.275 0.036
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.274 0.0688
SORL1 SORL1: Sortilin-related receptor precursor 0.274 0.0688
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.274 0.0688
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.274 0.0688
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.274 0.0688
PLK4 PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4 0.274 0.217
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.265 0.051
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.217
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.251 0.049
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.251 0.165
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.251 0.165
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.251 0.165
TNK1 TNK1: Non-receptor tyrosine-protein kinase TNK1 0.237 0.237
ACTR3 ACTR3, ARP3: Actin-related protein 3 0.233 0.044
ACTG1 ACTB: Actin, cytoplasmic 1 0.233 0.044
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.227 0.025
ATM ATM: Serine-protein kinase ATM 0.225 0.148
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.225 0.044
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.225 0.098
CHP CHP: Calcium-binding protein p22 0.225 0.036
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.225 0.165
VRK1 VRK1: Serine/threonine-protein kinase VRK1 0.225 0.148
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.225 0.148
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.225 0.148
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.225 0.098
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.225 0.148
GRAP GRAP: GRB2-related adapter protein 0.218 9.04
FGFR2 N/A 0.217 0.141
CSPG2 N/A 0.214 0.0688
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.210 0.049
CCR5 CCR5: CCR5 receptor (Fragment) 0.202 0.0688
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.202 0.0688
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.202 0.028
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.202 0.0688
DDR1 DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con 0.195 0.126
GAB1 GAB1: GRB2-associated-binding protein 1 0.191 0.165
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.191 0.165
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.191 0.109
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.191 0.165
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.191 0.165
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.191 0.098
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.188 0.044
PCBP1 PCBP1: Poly(rC)-binding protein 1 0.188 0.044
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.185 0.025
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.181 0.148
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.181 0.047
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.181 0.148
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.171 0.098
CDK6 CDK6: Cell division protein kinase 6 0.171 0.165
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.171 0.165
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.171 0.098
CCT2 CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta 0.171 0.098
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.171 0.148
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.171 0.148
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.171 0.148
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.171 0.148
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.171 0.148
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.171 1.37
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.171 0.148
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.171 0.098
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.171 0.098
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.166 0.028
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.166 0.0688
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.166 0.0688
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.165 0.049
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.165 0.044
DNM3 DNM3: Uncharacterized protein DNM3 0.165 0.109
CNN2 CNN2: Calponin-2 0.165 0.109
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.165 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.165 0.109
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.165 0.148
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.165 0.165
PPEF1 N/A 0.165 0.165
MAPKAPK5 N/A 0.165 0.165
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.165 0.109
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.165 0.165
MAP2K5 N/A 0.165 0.109
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.165 0.165
NF2 NF2, SCH: Merlin 0.165 0.165
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.165 0.165
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.165 0.165
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.165 0.148
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.165 0.148
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.165 0.109
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.165 0.109
EEF2K EEF2K: Elongation factor 2 kinase 0.165 0.148
AMPH AMPH, AMPH1: Amphiphysin 0.165 0.109
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.165 0.036
PSCD2 N/A 0.165 0.109
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.165 0.165
CDC2 CDC2: Cell division control protein 2 homolog 0.165 0.148
MAPK15 N/A 0.165 0.165
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.165 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.165 0.049
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.165 0.049
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.165 0.109
ALOX5 ALOX5, LOG5: Arachidonate 5-lipoxygenase 0.163 0.04
STYK1 STYK1, NOK: Tyrosine protein-kinase STYK1 0.162 0.141
RYK RYK, JTK5A: Tyrosine-protein kinase RYK precursor 0.162 0.141
CDC42EP3 CDC42EP3, BORG2, CEP3: Cdc42 effector protein 3 0.160 0.051
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 0.156 9.04
CMTM6 CMTM6, CKLFSF6: CKLF-like MARVEL transmembrane domain-containing protein 6 0.156 0.034
FUBP1 N/A 0.155 0.049
FPR1 FPR1: fMet-Leu-Phe receptor 0.153 0.034
C5AR1 C5AR1, C5AR, C5R1: C5a anaphylatoxin chemotactic receptor 0.153 0.034
PRKAA1 N/A 0.152 0.165
LIMK2 LIMK2: LIM domain kinase 2 0.152 0.109
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.152 0.165
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.152 0.04
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.152 0.165
STK16 N/A 0.152 0.165
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.152 0.165
SOS1 SOS1: Son of sevenless homolog 1 0.148 0.148
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.148 0.062
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.148 0.148
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.148 0.044
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.148 0.148
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.148 0.148
ACTN4 ACTN4: Alpha-actinin-4 0.148 0.098
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.148 0.109
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.148 0.148
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.148 0.148
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.148 0.098
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.148 0.148
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.148 0.098
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.148 0.165
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.148 0.148
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.148 0.098
ELMO1 N/A 0.148 0.148
CDC25C CDC25C: M-phase inducer phosphatase 3 0.148 0.025
ARHGEF7 N/A 0.148 0.098
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.148 0.098
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.148 0.098
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.148 0.148
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.148 0.148
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.148 0.148
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.148 0.036
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.148 0.098
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.148 0.148
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.148 0.148
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.148 0.04
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.148 0.148
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.148 0.148
CDC25A CDC25A: M-phase inducer phosphatase 1 0.148 0.025
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.148 0.098
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.148 0.098
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.148 0.148
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.148 0.148
TYRO3 TYRO3, BYK, DTK, RSE, SKY: Tyrosine-protein kinase receptor TYRO3 precursor 0.145 0.141
RET urf-ret: Urf-ret protein 0.145 0.141
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.144 0.049
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.143 0.141
THOC1 THOC1, HPR1: THO complex subunit 1 0.139 0.044
PCBP2 PCBP2: Poly(rC)-binding protein 2 0.139 0.044
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.139 0.028
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.139 0.098
PLEKHO1 PLEKHO1, CKIP1, OC120, HQ0024c: Pleckstrin homology domain-containing family O m 0.137 0.027
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.137 0.030
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.137 0.025
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.136 0.148
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.136 0.036
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.136 0.148
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.136 0.148
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.136 71.20
CDK5 CDK5: Cell division protein kinase 5 0.136 0.148
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.136 0.148
CDK7 CDK7, MO15: Cell division protein kinase 7 0.136 0.148
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.136 0.148
CDK2 CDK2: Cell division protein kinase 2 0.136 0.148
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.136 0.098
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.136 0.165
RASA3 RASA3: Ras GTPase-activating protein 3 0.136 0.098
VIL2 N/A 0.136 0.098
PLD2 PLD2: Phospholipase D2 0.136 0.098
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.136 0.098
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.136 0.036
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.136 0.148
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.136 0.148
TSC1 TSC1, KIAA0243, TSC: Hamartin 0.136 0.028
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.136 0.148
CDK4 CDK4: Cell division protein kinase 4 0.136 0.148
MUSK MUSK: Muscle, skeletal receptor tyrosine protein kinase precursor 0.130 0.141
ROR2 ROR2, NTRKR2: Tyrosine-protein kinase transmembrane receptor ROR2 precursor 0.130 0.126
KIAA1012 KIAA1012: Protein TRS85 homolog 0.129 0.025
AMHR2 AMHR2, AMHR: Anti-Muellerian hormone type-2 receptor precursor 0.129 0.141
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.128 0.126
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.126 0.165
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.126 0.165
IL8RB IL8RB, CXCR2: High affinity interleukin-8 receptor B 0.126 0.034
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.126 0.062
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.126 0.0688
CD7 CD7: T-cell antigen CD7 precursor 0.126 0.0688
ETS2 ETS2: Protein C-ets-2 0.126 0.165
EPOR EPOR: Erythropoietin receptor precursor 0.126 0.0688
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.124 0.034
H1FX H1FX: Histone H1x 0.124 0.083
DAPK2 DAPK2: Death-associated protein kinase 2 0.123 0.165
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.123 0.165
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.123 0.109
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.123 0.047
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.123 0.109
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.123 0.165
COPA COPA: Coatomer subunit alpha 0.118 0.025
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.116 0.046
INSRR INSRR, IRR: Insulin receptor-related protein precursor 0.115 0.126
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.114 0.062
FXR1 FXR1: Fragile X mental retardation syndrome-related protein 1 0.114 0.044
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.113 0.156
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.113 0.148
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.111 0.075
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.111 0.030
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.111 0.148
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.111 0.165
DYRK3 N/A 0.111 0.148
RDX RDX: Radixin 0.111 0.098
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.111 0.098
WEE1 WEE1: Wee1-like protein kinase 0.111 0.165
ACTN1 ACTN1: Alpha-actinin-1 0.111 0.098
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.111 0.148
COBL N/A 0.110 0.109
SPTAN1 N/A 0.110 0.109
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.110 0.148
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.110 0.148
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.110 0.148
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.109 0.0688
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.109 0.0688
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.109 0.0688
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.109 0.0688
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.109 0.0688
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.109 0.0688
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.109 0.0688
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.109 0.0688
KIR3DL1 N/A 0.109 0.0688
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.109 0.0688
FN1 N/A 0.109 0.0688
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.109 0.0688
LAT LAT: Linker for activation of T-cells family member 1 0.109 0.0688
NULL A1BG: Alpha-1B-glycoprotein precursor 0.109 0.0688
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.109 0.0688
NSBP1 NSBP1: Nucleosome-binding protein 1 0.109 0.028
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.109 0.0688
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.109 0.0688
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.109 0.0688
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.109 0.0688
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.109 0.0688
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.109 0.0688
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.109 0.0688
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.109 0.0688
DRD2 DRD2: D(2) dopamine receptor 0.109 0.034
S100A7 S100A7, PSOR1: Protein S100-A7 0.109 0.049
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.109 0.109
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.109 0.165
CDKL5 N/A 0.109 0.165
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.109 0.165
IRS1 IRS1: Insulin receptor substrate 1 0.109 0.165
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.109 0.165
TNNC1 TNNC1, TNNC: Troponin C, slow skeletal and cardiac muscles 0.109 0.04
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.109 0.165
NUP214 N/A 0.101 0.028
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.100 0.0688
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.100 0.0688
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.100 0.0688
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.100 0.0688
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.100 0.165
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.100 0.0688
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.100 0.0688
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.100 0.148
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.099 0.148
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.099 0.098
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.099 0.165
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.099 0.098
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.099 0.098
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.099 0.148
TLN2 TLN2: Uncharacterized protein TLN2 0.099 0.098
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.099 0.036
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.099 0.098
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.099 0.098
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.098 0.04
SNCB SNCB: Beta-synuclein 0.098 0.04
S100B S100B: Protein S100-B 0.098 0.049
GRLF1 N/A 0.098 0.083
MT3 MT3: Metallothionein-3 0.098 0.109
MCF2 MCF2, DBL: Proto-oncogene DBL 0.098 0.109
S100A3 S100A3, S100E: Protein S100-A3 0.098 0.049
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.098 0.04
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.098 0.148
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.098 0.062
CNTN1 CNTN1: Contactin-1 precursor 0.098 0.062
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.098 0.030
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.098 0.062
BSG N/A 0.098 0.062
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.098 0.062
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.098 0.148
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.098 0.062
CNTN4 CNTN4: Contactin-4 precursor 0.098 0.062
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.098 0.148
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.098 0.148
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.098 0.148
CETN1 CETN1, CEN1, CETN: Centrin-1 0.098 0.052
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.098 0.148
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.098 0.062
PKMYT1 PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito 0.097 0.148
DAB2 DAB2, DOC2: Disabled homolog 2 0.097 0.148
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.097 0.148
STK39 STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase 0.097 0.098
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.097 0.148
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.097 0.098
PSD TYL: TYL protein 0.097 0.098
TTN N/A 0.097 0.148
SORBS3 SORBS3, SCAM1: Vinexin 0.097 0.098
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.097 0.148
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.097 0.098
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 0.097 0.098
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.097 0.098
MYL3 MYL3: Myosin light polypeptide 3 0.097 0.036
DAB1 DAB1: Disabled homolog 1 0.097 0.148
PLD1 PLD1: Phospholipase D1 0.097 0.098
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.097 0.098
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.097 0.148
PRKCB1 PRKCB1, PKCB, PRKCB: Protein kinase C beta type 0.0955 0.051
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.091 0.034
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.091 0.034
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.090 0.025
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.090 0.025
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.090 0.025
CORO1C CORO1C, CRNN4: Coronin-1C 0.090 0.025
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.090 0.148
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.088 0.148
MYO3A MYO3A: Myosin IIIA 0.088 0.148
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.088 0.036
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.088 0.148
CAMK2D CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain 0.088 0.148
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.088 0.148
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.088 0.036
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.088 0.098
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.088 0.148
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.088 0.148
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.088 0.04
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.088 0.148
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.088 0.098
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.088 0.098
CTTN CTTN, EMS1: Src substrate cortactin 0.088 0.109
CNN3 CNN3: Calponin-3 0.088 0.109
LIMS1 N/A 0.087 0.049
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.087 0.028
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.087 0.028
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.087 0.025
RGS19 RGS19, GAIP, GNAI3IP: Regulator of G-protein signaling 19 0.087 0.044
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.087 0.152
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.087 0.025
MDN1 MDN1, KIAA0301: Midasin 0.086 0.025
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.083 0.049
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.083 0.083
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.0818 0.075
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.0818 0.052
MYH9 MYH9: Myosin-9 0.0818 0.148
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.081 0.0688
GPA33 GPA33: Cell surface A33 antigen precursor 0.081 0.0688
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.081 0.0688
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.081 0.0688
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.081 0.0688
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.081 0.0688
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.081 0.0688
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.081 0.0688
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.081 0.0688
IL9R IL9R: Interleukin-9 receptor precursor 0.081 0.0688
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.081 0.0688
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.081 0.0688
CENTA1 CENTA1: Centaurin-alpha 1 0.0794 0.0688
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.078 0.148
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.078 0.036
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.078 0.148
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.078 0.025
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.078 0.025
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.078 0.044
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.078 0.025
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.078 0.028
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.077 0.028
RAB32 RAB32: Ras-related protein Rab-32 0.076 0.165
TNF TNF, TNFA, TNFSF2: Tumor necrosis factor precursor 0.075 0.034
FPRL1 FPRL1, FPR2, FPRH1, LXA4R: FMLP-related receptor I 0.075 0.034
IRF3 IRF3: Interferon regulatory factor 3 0.075 0.165
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.075 0.044
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.074 0.0688
WDR1 N/A 0.074 0.028
SH3BP3 0.074 0.028
GNB2L1 Lung cancer oncogene 7 0.074 0.028
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.074 0.025
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.073 0.0688
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.073 0.165
DCC DCC: Netrin receptor DCC precursor 0.073 0.062
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.073 0.148
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.0727 0.0688
PVR PVR, PVS: Poliovirus receptor precursor 0.0727 0.0688
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.0727 0.0688
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.0727 0.0688
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.0727 0.0688
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.0727 0.0688
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.072 0.165
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.072 0.0688
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.072 0.0688
EGF EGF: Pro-epidermal growth factor precursor 0.072 0.0688
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.072 0.0688
TP73 TP73, P73: Tumor protein p73 0.072 0.165
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.072 0.0688
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.072 0.0688
GHR GHR: Growth hormone receptor precursor 0.072 0.0688
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.072 0.0688
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.072 0.0688
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.071 0.025
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.071 0.025
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.071 0.025
MARK2 N/A 0.070 0.028
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.070 0.028
SAT SAT1, SAT: Diamine acetyltransferase 1 0.070 0.028
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.070 0.028
MVP MVP, LRP: Major vault protein 0.070 0.04
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.070 0.028
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.070 0.028
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.0688 0.0688
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.0688 0.0688
SAMD9 SAMD9, C7orf5, DRIF1, KIAA2004, OEF1: Sterile alpha motif domain-containing prot 0.067 0.027
CENTA2 CENTA2: Centaurin-alpha 2 0.067 0.027
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.067 0.030
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.067 0.025
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.067 0.025
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.067 0.030
SEC31L1 N/A 0.067 0.025
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.066 0.075
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.066 0.025
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.066 0.025
JUNB JUNB: Transcription factor jun-B 0.066 0.075
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.065 0.062
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.065 0.062
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.065 0.0688
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.065 0.0688
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.065 0.0688
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.065 0.0688
F3 F3: Tissue factor precursor 0.065 0.0688
ITGB4 N/A 0.065 0.0688
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.065 0.165
SCML2 SCML2: Sex comb on midleg-like protein 2 0.065 0.165
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.065 0.165
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.065 0.034
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.065 0.0688
PRLR PRLR: Prolactin receptor precursor 0.065 0.0688
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.065 0.0688
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.065 0.0688
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.065 0.0688
TNC TNC, HXB: Tenascin precursor 0.064 0.062
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.064 0.062
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.064 0.062
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.064 0.062
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.064 0.062
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.064 0.062
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.064 0.062
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.064 0.148
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.063 0.025
GSK3B N/A 0.063 0.025
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.063 0.025
DIAPH1 Diaphanous 1 0.063 0.025
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.063 0.098
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.062 0.075
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.062 0.044
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.062 0.049
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.062 0.062
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.062 0.062
NFATC1 N/A 0.061 0.083
TRIB1 TRIB1, C8FW, GIG2, TRB1: Tribbles homolog 1 0.060 0.027
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.058 0.148
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.058 0.062
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.058 0.062
DRD1 DRD1: D(1A) dopamine receptor 0.058 0.030
PTPRZ1 N/A 0.058 0.0688
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.058 0.0688
FADD FADD, MORT1: Protein FADD 0.057 0.034
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.057 0.034
TOP2A TOP2A, TOP2: DNA topoisomerase 2-alpha 0.057 0.028
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.057 0.028
MCOLN1 MCOLN1, ML4, MSTP080: Mucolipin-1 0.056 0.062
PRKACB PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit 0.056 0.165
GRK7 GRK7, GPRK7: G protein-coupled receptor kinase 7 precursor 0.056 0.056
HDLBP HDLBP, HBP, VGL: Vigilin 0.056 0.044
FABP5 FABP5: Fatty acid-binding protein, epidermal 0.055 0.044
FABP1 FABP1, FABPL: Fatty acid-binding protein, liver 0.055 0.049
COPB2 COPB2: Coatomer subunit beta' 0.054 0.025
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.054 0.028
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.054 0.025
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.054 0.025
TAOK1 TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1 0.053 0.046
CHUK N/A 0.052 0.028
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.052 0.028
ZYX ZYX: Zyxin 0.052 0.049
FLNA FLNA, FLN, FLN1: Filamin-A 0.052 0.109
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.052 0.028
NULL Ig lambda chain V-II region NEI 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
IGHD N/A 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
IGHG1 N/A 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
HLA-A N/A 0.051 0.051
IGHM N/A 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
GSK3B GSK3B: Glycogen synthase kinase-3 beta 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
MAPK11 MAPK11, PRKM11, SAPK2: Mitogen-activated protein kinase 11 0.051 0.051
CDC42EP1 CDC42EP1, BORG5, CEP1, MSE55: Cdc42 effector protein 1 0.051 0.051
PRKCD PRKCD: Protein kinase C delta type 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
PTPRA N/A 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
C9orf88 N/A 0.051 0.051
NCAM1 N/A 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
RAPH1 N/A 0.051 0.051
CHUK CHUK, IKKA, TCF16: Inhibitor of nuclear factor kappa-B kinase subunit alpha 0.051 0.051
IGHG3 N/A 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
IGHA1 N/A 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
UBAP2L N/A 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
MAP4K4 N/A 0.051 0.051
MARK2 N/A 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
NULL Ig kappa chain V-I region CAR 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
MAPK7 MAPK7, ERK4, ERK5, PRKM7: Mitogen-activated protein kinase 7 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.051 0.0688
TP53 TP53, P53: Cellular tumor antigen p53 0.051 0.187
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.051 0.075
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.051 0.047
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.051 0.025
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.050 0.050
ARHGEF18 ARHGEF18: ARHGEF18 protein 0.050 0.027
CSNK1G3 CSNK1G3: Casein kinase I isoform gamma-3 0.050 0.027
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.049 0.034
C3AR1 C3AR1, AZ3B, C3R1, HNFAG09: C3a anaphylatoxin chemotactic receptor 0.049 0.034
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.049 0.034
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.049 0.034
HES6 HES6: Transcription cofactor HES-6 0.049 0.083
ATP2A3 ATP2A3: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 0.049 0.034
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.049 0.034
BID BID: BH3-interacting domain death agonist 0.049 0.028
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.049 0.034
TBXA2R TBXA2R: Thromboxane A2 receptor 0.049 0.034
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.049 0.034
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.049 0.034
FXR2 FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2 0.049 0.044
JUP JUP, CTNNG, DP3: Junction plakoglobin 0.049 0.036
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.048 0.049
PHB2 PHB2, BAP, REA: Prohibitin-2 0.048 0.04
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.047 0.046
TNKS2 TNKS2, PARP5B, TANK2, TNKL: Tankyrase-2 0.047 0.027
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.047 0.044
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.047 0.025
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.046 0.028
KLHDC4 N/A 0.046 0.028
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.028
COPE COPE: Coatomer subunit epsilon 0.046 0.025
LPXN LPXN, LDLP: Leupaxin 0.046 0.044
EXOC2 N/A 0.046 0.044
BRPF1 BRPF1, BR140: Peregrin 0.046 0.075
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.046 0.025
PPIA PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A 0.046 0.030
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.025
SAPS3 N/A 0.046 0.025
KIAA0690 N/A 0.046 0.025
NEO1 NEO1, NGN: Neogenin precursor 0.046 0.062
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.046 0.0688
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.046
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.046 0.051
SRPK1 SRPK1: Serine/threonine-protein kinase SRPK1 0.046 0.046
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.046
EPB41 EPB41, E41P: Protein 4.1 0.046 0.046
TLK2 TLK2: Serine/threonine-protein kinase tousled-like 2 0.046 0.046
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.046
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.046 0.046
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.046
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.046
TBC1D4 TBC1D4: TBC1D4 protein 0.046 0.051
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.046
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.046
LMO7 N/A 0.046 0.046
IKBKE IKBKE, IKKE, IKKI, KIAA0151: Inhibitor of nuclear factor kappa-B kinase subunit 0.046 0.046
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.046 0.050
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.046 0.062
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.046 0.0688
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.046 0.0688
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.046 0.0688
F2RL3 F2RL3, PAR4: Proteinase-activated receptor 4 precursor 0.0453 0.034
SLC9A1 SLC9A1, APNH1, NHE1: Sodium/hydrogen exchanger 1 0.0453 0.0688
GPR23 LPA4, GPR23, P2RY9: Lysophosphatidic acid receptor 4 0.0453 0.034
ERF ERF: ETS domain-containing transcription factor ERF 0.0453 0.083
ATP2B1 N/A 0.0453 0.034
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.045 0.034
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.045 0.0688
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.045 0.0688
RYR2 RYR2: Ryanodine receptor 2 0.045 0.0688
BACH1 BACH1: Transcription regulator protein BACH1 0.0446 0.083
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.0446 0.052
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.0446 0.083
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.0446 0.028
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.0446 0.028
ELF1 ELF1: ETS-related transcription factor Elf-1 0.0446 0.083
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.044 0.078
PMP2 PMP2: Myelin P2 protein 0.044 0.044
ATRN N/A 0.044 0.030
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.044 0.075
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.044 0.025
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.044 0.030
CCNT2 CCNT2: Cyclin-T2 0.044 0.025
CREB1 CREB1: cAMP response element-binding protein 0.044 0.075
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.044 0.030
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.044 0.062
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.044 0.025
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.044 0.030
SUPT5H SUPT5H, SPT5, SPT5H: Transcription elongation factor SPT5 0.044 0.029
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.0425 0.028
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.0425 0.025
API5 N/A 0.0425 0.028
SLC9A3R1 SLC9A3R1, NHERF: Ezrin-radixin-moesin-binding phosphoprotein 50 0.0425 0.049
TNN TNN: Tenascin-N precursor 0.042 0.046
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.042 0.046
MCM3 MCM3: DNA replication licensing factor MCM3 0.041 0.047
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.041 0.025
MCM2 MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2 0.041 0.047
VWF VWF, F8VWF: von Willebrand factor precursor 0.041 0.062
RPS6KA6 RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6 0.041 0.062
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.041 0.0688
FKBP10 FKBP10, FKBP65, PSEC0056: FK506-binding protein 10 precursor 0.041 0.030
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.041 0.0688
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.041 0.0688
RYR1 0.041 0.062
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.041 0.0688
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.041 0.0688
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.041 0.030
TRHR TRHR: Thyrotropin-releasing hormone receptor 0.041 0.030
CCNH CCNH: Cyclin-H 0.041 0.025
SLC9A7 SLC9A7, NHE7: Sodium/hydrogen exchanger 7 0.041 0.062
NPM1 NPM1, NPM: Nucleophosmin 0.041 0.028
VRK3 N/A 0.041 0.027
ASB8 ASB8, PP14212: Ankyrin repeat and SOCS box protein 8 0.041 0.027
DYRK2 DYRK2: Dual specificity tyrosine-phosphorylation-regulated kinase 2 0.041 0.027
SAMSN1 SAMSN1, HACS1: SAM domain-containing protein SAMSN-1 0.041 0.027
STYXL1 STYXL1, DUSP24, MKSTYX: Serine/threonine/tyrosine-interacting-like protein 1 0.041 0.027
ARHGEF3 ARHGEF3: Rho guanine nucleotide exchange factor 3 0.041 0.027
CAMK2G Calcium/calmodulin-dependent protein kinase isoform A (Fragment) 0.041 0.027
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.041 0.062
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.041 0.062
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.041 0.062
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.041 0.062
DLG2 DLG2: Disks large homolog 2 0.041 0.062
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.04 0.083
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.04 0.028
WDR54 N/A 0.04 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.04 0.083
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.040 0.025
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.040 0.025
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.040 0.025
JUND JUND: Transcription factor jun-D 0.040 0.075
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.040 0.025
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.040 0.025
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.040 0.025
YY1 YY1: Transcriptional repressor protein YY1 0.040 0.025
MTF1 MTF1: Metal regulatory transcription factor 1 0.040 0.025
KCTD12 KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12 0.040 0.047
EP300 N/A 0.040 0.137
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.040 0.025
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.040 0.025
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.040 0.025
STOML2 STOML2, SLP2, HSPC108: Stomatin-like protein 2 0.039 0.04
APBA3 APBA3, MINT3, X11L2: Amyloid beta A4 precursor protein-binding family A member 3 0.039 0.027
PLK3 PLK3, CNK, FNK, PRK: Serine/threonine-protein kinase PLK3 0.039 0.027
PPP2CA PPP2CA: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform 0.038 0.044
YBX1 YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1 0.038 0.047
FKBP5 FKBP5, AIG6, FKBP51: FK506-binding protein 5 0.038 0.075
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.038 0.025
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.038 0.044
KCNJ3 KCNJ3, GIRK1: G protein-activated inward rectifier potassium channel 1 0.037 0.034
MYB MYB: Myb proto-oncogene protein 0.037 0.028
MDM4 MDM4, MDMX: Mdm4 protein 0.037 0.028
F2R F2R, CF2R, PAR1, TR: Proteinase-activated receptor 1 precursor 0.037 0.034
EDG1 EDG1: Sphingosine 1-phosphate receptor Edg-1 0.037 0.034
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.037 0.034
F2RL1 F2RL1, GPR11, PAR2: Proteinase-activated receptor 2 precursor 0.037 0.034
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.037 0.028
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.037 0.034
TERT TERT, EST2, TCS1, TRT: Telomerase reverse transcriptase 0.037 0.028
HRB2 KRR1, HRB2: KRR1 small subunit processome component homolog 0.037 0.044
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.037 0.062
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.037 0.062
FKBP9 FKBP9, FKBP60, FKBP63: FK506-binding protein 9 precursor 0.037 0.030
UBADC1 UBADC1, GBDR1, KPC2: Ubiquitin-associated domain-containing protein 1 0.036 0.027
SP100 N/A 0.036 0.028
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.036 0.028
NBN NBN, NBS, NBS1, P95: Nibrin 0.036 0.052
NCOA3 N/A 0.036 0.028
PTMA N/A 0.036 0.028
ID2 ID2: DNA-binding protein inhibitor ID-2 0.036 0.028
KIAA0853 N/A 0.036 0.028
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.036 0.028
IFI16 N/A 0.036 0.028
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.036 0.028
GEMIN5 GEMIN5: Gem-associated protein 5 0.036 0.028
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.036 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.036 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.036 0.025
DYNC1I2 N/A 0.035 0.025
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.035 0.025
GABPA GABPA, E4TF1A: GA-binding protein alpha chain 0.035 0.027
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.034 0.051
TNIK TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase 0.0338 0.051
MAL2 MAL2: Protein MAL2 0.034 0.034
OPRM1 OPRM1, MOR1: Mu-type opioid receptor 0.034 0.030
GTF2A1 GTF2A1, TF2A1: Transcription initiation factor IIA subunit 1 0.033 0.025
CCNB1 Cyclin B1 0.033 0.025
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.033 0.075
CDC20 CDC20: Cell division cycle protein 20 homolog 0.033 0.025
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.033 0.187
RAP1GA1 N/A 0.033 0.034
RHO RHO, OPN2: Rhodopsin 0.033 0.034
ETV1 ETV1, ER81: ETS translocation variant 1 0.033 0.083
HTR6 HTR6: 5-hydroxytryptamine receptor 6 0.032 0.034
MC4R MC4R: Melanocortin receptor 4 0.032 0.034
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.032 0.0688
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.032 0.034
F2RL2 F2RL2, PAR3: Proteinase-activated receptor 3 precursor 0.032 0.034
ABCF1 N/A 0.032 0.028
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.032 0.028
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.032 0.083
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.032 0.028
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.032 0.025
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.032 0.025
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.032 0.047
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.032 0.028
CUL5 CUL5, VACM1: Cullin-5 0.032 0.025
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.032 0.025
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.032 0.075
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.032 0.025
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.032 0.025
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.032 0.075
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.032 0.025
WDR44 WDR44: WD repeat-containing protein 44 0.032 0.025
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.032 0.025
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.032 0.025
JUN JUN: Transcription factor AP-1 0.032 0.075
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.032 0.075
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.032 0.025
SP3 SP3: Transcription factor Sp3 0.032 0.025
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.032 0.025
PHF10 N/A 0.032 0.025
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 0.032 0.025
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.032 0.025
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.032 0.025
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.032 0.025
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.032 0.025
HDAC3 HDAC3: Histone deacetylase 3 0.032 0.083
CDC14A CDC14A: Dual specificity protein phosphatase CDC14A 0.032 0.027
CD6 CD6: T-cell differentiation antigen CD6 precursor 0.031 0.030
LDLRAP1 LDLRAP1, ARH: Low density lipoprotein receptor adapter protein 1 0.0308 0.027
EIF2AK1 N/A 0.0308 0.027
NUAK1 NUAK1, ARK5, KIAA0537: NUAK family SNF1-like kinase 1 0.031 0.046
CNN1 CNN1: Calponin-1 0.030 0.051
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.030 0.051
SYNGR2 SYNGR2, UNQ352/PRO615: Synaptogyrin-2 0.030 0.030
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.030 0.156
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.030 0.137
HES1 HES1, HL, HRY: Transcription factor HES-1 0.029 0.075
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.029 0.075
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.029 0.030
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.029 0.030
CHRM2 CHRM2: Muscarinic acetylcholine receptor M2 0.029 0.030
TSPYL2 TSPYL2, CDA1, HRIHFB2216, DENTT, TSPX: Testis-specific Y-encoded-like protein 2 0.029 0.028
HMGA2 HMGA2, HMGIC: High mobility group protein HMGI-C 0.029 0.028
SALF GTF2A1L, ALF, GTF2A1LF: TFIIA-alpha and beta-like factor 0.029 0.028
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.029 0.034
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.029 0.034
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.029 0.034
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.029 0.034
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.029 0.034
SSTR3 SSTR3: Somatostatin receptor type 3 0.029 0.030
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.029 0.030
TSHR N/A 0.029 0.030
HPN HPN, TMPRSS1: Serine protease hepsin 0.029 0.034
SYMPK SYMPK, SPK: Symplekin 0.029 0.025
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.029 0.075
FHOD1 FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1 0.029 0.025
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.075
DNAJC7 DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7 0.029 0.028
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.029 0.075
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
MUSK MUSK: MUSK protein 0.0288 0.0288
NULL N/A 0.0288 0.0288
NTRK3 NTRK3, TRKC: NT-3 growth factor receptor precursor 0.0288 0.0288
NTRK3 N/A 0.0288 0.0288
ROS1 ROS1: Proto-oncogene tyrosine-protein kinase ROS precursor 0.0288 0.0288
NULL Tyrosine kinase 0.0288 0.0288
TESK2 TESK2: Dual specificity testis-specific protein kinase 2 0.0288 0.0288
TTN TTN: Uncharacterized protein TTN (Fragment) 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
DDR2 DDR2, NTRKR3, TKT, TYRO10: Discoidin domain-containing receptor 2 precursor 0.0288 0.0288
NULL N/A 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
AATK apoptosis-associated tyrosine kinase 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PHLDB2 N/A 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
AXIN1 0.028 0.049
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.028 0.049
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
RGS18 RGS18, RGS13: Regulator of G-protein signaling 18 0.028 0.049
YWHAG YWHAG: 14-3-3 protein gamma 0.028 0.0333
PDZD2 CDNA FLJ46853 fis, clone UTERU3009775, moderately similar to Rattus norvegicus P 0.028 0.049
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.028 0.083
GOPC GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein 0.028 0.044
STK17A STK17A, DRAK1: Serine/threonine-protein kinase 17A 0.028 0.027
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.027 1.37
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.027 0.025
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.027 0.025
ASB14 ASB14: Ankyrin repeat and SOCS box protein 14 0.027 0.027
ASB7 ASB7: Ankyrin repeat and SOCS box protein 7 0.027 0.027
CAMKK1 CAMKK1, CAMKKA: Calcium/calmodulin-dependent protein kinase kinase 1 0.027 0.027
DOK5 DOK5, C20orf180: Docking protein 5 0.027 0.027
CASKIN1 N/A 0.027 0.027
ASB12 ASB12: Ankyrin repeat and SOCS box protein 12 0.027 0.027
UBL7 UBL7, BMSCUBP, SB132: Ubiquitin-like protein 7 0.027 0.027
CENTB5 KIAA1716, CENTB5: Centaurin-beta 5 0.027 0.027
RASGRF2 RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment) 0.027 0.027
FANK1 FANK1, HSD13, UNQ6504/PRO21382: Fibronectin type 3 and ankyrin repeat domains pr 0.027 0.027
SHANK1 SHANK1: SH3 and multiple ankyrin repeat domains protein 1 0.027 0.027
ASB6 ASB6: Ankyrin repeat and SOCS box protein 6 0.027 0.027
PDIK1L PDIK1L, CLIK1L: Serine/threonine-protein kinase PDIK1L 0.027 0.027
APBB1 APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1 0.027 0.027
NEK11 NEK11: Serine/threonine-protein kinase Nek11 0.027 0.027
MID2 N/A 0.027 0.027
CDC2L2 N/A 0.027 0.027
DUSP10 DUSP10, MKP5: Dual specificity protein phosphatase 10 0.027 0.027
FAM43A N/A 0.027 0.027
NEK4 NEK4, STK2: Serine/threonine-protein kinase Nek4 0.027 0.027
PPP1R9A PPP1R9A, KIAA1222: Neurabin-1 0.027 0.027
WSB1 WSB1, SWIP1: WD repeat and SOCS box-containing protein 1 0.027 0.027
ASB3 ASB3: ASB3 protein 0.027 0.027
SRA1 APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3 0.027 0.027
OSBPL9 N/A 0.027 0.027
RASGRF1 RASGRF1, CDC25: Guanine nucleotide-releasing protein 0.027 0.027
RIPK5 RIPK5, KIAA0472, HDCMD38P, RIP5, SGK496: Receptor-interacting serine/threonine-p 0.027 0.027
PLEKHA3 PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3 0.027 0.027
STK35 STK35, CLIK1, PDIK1: Serine/threonine-protein kinase 35 0.027 0.027
ASB10 ASB10: Ankyrin repeat and SOCS box protein 10 0.027 0.027
ARHGEF1 ARHGEF1: Rho guanine nucleotide exchange factor 1 0.027 0.027
TRIM9 TRIM9, KIAA0282, RNF91: Tripartite motif-containing protein 9 0.027 0.027
VEPH1 VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h 0.027 0.027
ASB17 ASB17: Ankyrin repeat and SOCS box protein 17 0.027 0.027
ALS2CR7 ALS2CR7: Serine/threonine-protein kinase ALS2CR7 0.027 0.027
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.027 0.028
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.027 0.083
TOP2B N/A 0.027 0.028
ZNF267 ZNF267: Zinc finger protein 267 0.027 0.028
RBM14 RBM14, SIP: RNA-binding protein 14 0.027 0.028
ARFGAP1 N/A 0.027 0.052
XRCC1 XRCC1: DNA-repair protein XRCC1 0.027 0.052
RGS14 N/A 0.027 0.028
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.027 0.028
AHR AHR: Aryl hydrocarbon receptor precursor 0.027 0.025
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.027 0.083
DDX21 DDX21: Nucleolar RNA helicase 2 0.027 0.028
VIM VIM: Vimentin 0.027 0.083
RB1 RB1: Retinoblastoma-associated protein 0.027 0.028
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.027 0.028
MEF2A N/A 0.027 0.028
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.027 0.028
ANXA9 ANXA9, ANX31: Annexin A9 0.0263 0.0688
KCNJ1 KCNJ1, ROMK1: ATP-sensitive inward rectifier potassium channel 1 0.0263 0.034
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.026 0.030
SLC9A3 SLC9A3, NHE3: Sodium/hydrogen exchanger 3 0.026 0.062
TACR2 TACR2, NK2R, NKNAR, TAC2R: Substance-K receptor 0.026 0.030
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.026 0.030
OR10H3 OR10H3: Olfactory receptor 10H3 0.026 0.030
HTR2C HTR2C, HTR1C: 5-hydroxytryptamine receptor 2C 0.026 0.030
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.026 0.030
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.026 0.025
FUT3 FUT3, FT3B, LE: Galactoside 3(4)-L-fucosyltransferase 0.026 0.030
P2RY4 P2RY4, NRU: P2Y purinoceptor 4 0.026 0.034
FES N/A 0.0258 0.0258
SHC2 N/A 0.0258 1.29
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.026 0.083
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.026 0.028
FAM65A FAM65A, KIAA1930: Protein FAM65A 0.026 0.028
UBAP2 N/A 0.026 0.028
EIF5AP1 EIF5A: Eukaryotic translation initiation factor 5A-1 0.026 0.052
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.026 0.044
FANCA FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein 0.026 0.028
TRRAP N/A 0.026 0.028
MARCO MARCO, SCARA2: Macrophage receptor MARCO 0.025 0.034
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
CAMK2A N/A 0.025 0.025
PRKCB1 N/A 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
CAMKK1 N/A 0.025 0.025
GRK6 N/A 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
LMO6 LMO6: LIM domain only protein 6 0.025 0.044
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.047
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
GIT2 N/A 0.025 0.047
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
MYO18A 0.025 0.109
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.025 0.044
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
NIPBL N/A 0.025 0.025
BCOR N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
0.572
Total Score 9.66E4