<<< Back to VPS4B

Evidence of Interaction Between VPS4B and CHMP4B

The interaction score between VPS4B and CHMP4B is 2.02E4.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

N/A
Orthology
OrganismVPS4B OrthologueCHMP4B OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00411356 0.489 IPI00023068 0.349
  • Y2H
  • InVivo

Get References From PubMed

bakers yeast YPR173C 1 YLR025W 0.349
  • Y2H
  • Other
  • AffinityCaptureMS

Get References From PubMed

worm Q9BL83 1 Q18886 1
worm Q9BL83 1 Q22916 0.392
fly Q9Y162 1 Q8T0Q4 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

3.01
Domains No domains were used in calculating likelihood of interaction 0.141
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation

Protein: VPS4B

LocalisationReference
Endosome HPRD
Vacuole HPRD
Cytoplasm HPRD

Protein: CHMP4B

LocalisationReference
Cytosol HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between VPS4B and CHMP4B that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between VPS4B andCHMP4B. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , VPS4B has 94 interactors and CHMP4B has 23 interactors of which there are 15 common interactors.

Common InteractorName of Common InteractorScore for VPS4B-Interactor (?)Score for CHMP4B-Interactor (?)
CHMP4A N/A 171.00 319.00
CHMP4C CHMP4C, SHAX3: Charged multivesicular body protein 4c 169.00 319.00
CHMP6 CHMP6, VPS20: Charged multivesicular body protein 6 83.90 319.00
PDCD6IP PDCD6IP, AIP1, ALIX, KIAA1375: Programmed cell death 6-interacting protein 1.84 0.143
CHMP1B CHMP1B, C18orf2: Charged multivesicular body protein 1b 0.724 0.265
VPS24 VPS24, CHMP3, CGI-149, NEDF: Charged multivesicular body protein 3 0.606 169.00
CHMP7 CHMP7: Charged multivesicular body protein 7 0.438 0.265
CHMP2B CHMP2B, CGI-84: Charged multivesicular body protein 2b 0.392 0.237
CHMP2A CHMP2A, BC2, CHMP2: Charged multivesicular body protein 2a 0.392 12.60
CHMP5 CHMP5, C9orf83, CGI-34, SNF7DC2, HSPC177, PNAS-2, PNAS-114: Charged multivesicul 0.317 0.237
LOC283683 N/A 0.119 0.064
SRPR SRPR: Uncharacterized protein SRPR 0.067 0.027
VPS4A VPS4A, VPS4: Vacuolar protein sorting-associating protein 4A 0.044 3.58
FBXO34 CGI-301: Protein CGI-301 0.0288 0.0288
PCOLN3 CHMP1A, CHMP1, KIAA0047, PCOLN3, PRSM1: Charged multivesicular body protein 1a 0.0288 0.0288
0.299
Total Score 2.02E4