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Evidence of Interaction Between TNF and TNFRSF1B

The interaction score between TNF and TNFRSF1B is 1.30.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between TNF and TNFRSF1B = 0.25

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 2.88E-3
Orthology N/A N/A
Domains Domains present in TNF and TNFRSF1B:
Domains in TNFDomains in TNFRSF1B
IPR002959 Tumour necrosis factor alpha/cachectin
IPR003636 Tumour necrosis factor subfamily
IPR006052 Tumor Necrosis Factor
IPR006053 Tumor necrosis factor alpha, beta and c
IPR008983 TNF-like
IPR001368 TNFR/CD27/30/40/95 cysteine-rich region
IPR011366 TNFrecept_2.

The Chi square scores for co-occurrence of domains that are present in TNF and TNFRSF1B are listed below.

Domain 1Domain 2Chi Square
IPR006052 Tumor Necrosis Factor IPR001368 TNFR/CD27/30/40/95 cysteine-rich region 686.654
IPR003636 Tumour necrosis factor subfamily IPR001368 TNFR/CD27/30/40/95 cysteine-rich region 549.921
IPR008983 TNF-like IPR001368 TNFR/CD27/30/40/95 cysteine-rich region 234.229
IPR006053 Tumor necrosis factor alpha, beta and c IPR001368 TNFR/CD27/30/40/95 cysteine-rich region 217.846

The background colour of the table refers to:

  • Blue Domain is only present in TNF
  • Yellow Domain is only present in TNFRSF1B
  • Green Domain is present in both TNF and TNFRSF1B

 1.30
Post-translational Modifications

Protein: TNF

PTMResidueReference
Myristoylation 19 PubMed, HPRD
Myristoylation 20 PubMed, HPRD
Phosphorylation 2 PubMed, HPRD
Phosphoserine 2 PubMed, HPRD
Proteolytic Cleavage 74 PubMed, HPRD
Proteolytic Cleavage 76 PubMed, HPRD
Proteolytic Cleavage 79 PubMed, HPRD

Protein: TNFRSF1B

PTMResidueReference
Phosphorylation 436 PubMed, HPRD
Localisation

Protein: TNF

LocalisationReference
Plasma membrane HPRD
Secreted HPRD

Protein: TNFRSF1B

LocalisationReference
Plasma membrane HPRD
Secreted HPRD
Transitive Score

The common interactors between TNF and TNFRSF1B that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between TNF andTNFRSF1B. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , TNF has 586 interactors and TNFRSF1B has 565 interactors of which there are 272 common interactors.

Common InteractorName of Common InteractorScore for TNF-Interactor (?)Score for TNFRSF1B-Interactor (?)
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 1.30 0.165
TNFRSF10C TNFRSF10C, DCR1, UNQ321/PRO366, LIT, TRAILR3, TRID: Tumor necrosis factor recept 0.975 0.127
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.975 0.515
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.859 0.109
LTA LTA, TNFB, TNFSF1: Lymphotoxin-alpha precursor 0.307 0.975
TNFRSF10A TNFRSF10A, APO2, DR4, TRAILR1: Tumor necrosis factor receptor superfamily member 0.265 0.027
TNFRSF10B TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9: Tumor necrosis factor receptor 0.265 0.027
TNFRSF25 TNFRSF25, APO3, UNQ455/PRO779, DDR3, DR3, TNFRSF12, WSL, WSL1: Tumor necrosis fa 0.265 0.027
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.251 0.070
SELL SELL, LNHR, LYAM1: L-selectin precursor 0.191 0.307
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.191 1.72
TNFSF12 TNFSF12, APO3L, UNQ181/PRO207, DR3LG: Tumor necrosis factor ligand superfamily m 0.191 14.30
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.166 0.340
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.165 1.30
EDA N/A 0.165 1.30
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.165 0.028
OPTC OPTC, OPT: Opticin precursor 0.165 0.028
ACE ACE, DCP, DCP1: Angiotensin-converting enzyme, somatic isoform precursor 0.165 0.028
RTN4R RTN4R, NOGOR, UNQ330/PRO526: Reticulon-4 receptor precursor 0.165 0.028
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.165 0.028
JAG2 JAG2: Jagged-2 precursor 0.165 0.028
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.165 1.30
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.028
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.028
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.165 1.30
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.165 0.028
DLK1 DLK1, DLK: Delta-like protein precursor 0.165 0.028
ITGB7 ITGB7: Integrin beta-7 precursor 0.155 0.0971
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.152 0.087
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.152 0.859
FADD FADD, MORT1: Protein FADD 0.152 0.251
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.152 0.032
THOC1 THOC1, HPR1: THO complex subunit 1 0.126 0.100
TRAF1 TRAF1, EBI6: TNF receptor-associated factor 1 0.126 0.731
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.126 0.274
CSPG2 N/A 0.126 0.074
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.126 0.274
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.124 0.074
CD40LG CD40LG, CD40L, TNFSF5, TRAP: CD40 ligand 0.123 1.20
LRP1 LRP1, A2MR, APR: Prolow-density lipoprotein receptor-related protein 1 precursor 0.123 0.032
MEP1A MEP1A: Meprin A subunit alpha precursor 0.123 0.859
MEP1B MEP1B: Meprin A subunit beta precursor 0.123 0.775
CASP9 CASP9, MCH6: Caspase-9 precursor 0.109 0.109
CASP8 CASP8, MCH5: Caspase-8 precursor 0.109 0.109
CASP1 CASP1, IL1BC, IL1BCE: Caspase-1 precursor 0.109 0.109
TNFSF15 TNFSF15, RP11-428F18.1-001, hCG_27396: TNF superfamily ligand TL1A 0.109 0.859
GP1BB GP1BB: Platelet glycoprotein Ib beta chain precursor 0.109 0.026
GP9 GP9: Platelet glycoprotein IX precursor 0.109 0.026
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.100 0.166
TRAF2 TRAF2, TRAP3: TNF receptor-associated factor 2 0.100 0.902
CASP2 CASP2, ICH1, NEDD2: Caspase-2 precursor 0.100 0.081
RPS10 RPS10: 40S ribosomal protein S10 0.100 0.202
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.100 0.166
TLR2 TLR2, TIL4: Toll-like receptor 2 precursor 0.096 0.307
TLR4 TLR4: Toll-like receptor 4 precursor 0.096 0.087
ST14 ST14, PRSS14, SNC19, TADG15: Suppressor of tumorigenicity protein 14 0.096 0.032
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.096 0.026
SORL1 SORL1: Sortilin-related receptor precursor 0.096 0.087
FNBP1 N/A 0.091 0.027
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.091 0.157
SYK SYK: Tyrosine-protein kinase SYK 0.091 0.0446
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.091 0.124
CXorf9 N/A 0.091 0.0446
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.091 0.253
HGF HGF, HPTA: Hepatocyte growth factor precursor 0.083 0.028
TMPRSS9 N/A 0.083 0.028
ATRN N/A 0.083 0.028
LRG1 LRG1, LRG: Leucine-rich alpha-2-glycoprotein precursor 0.083 0.028
CD14 CD14: Monocyte differentiation antigen CD14 precursor 0.077 0.307
VAV1 VAV1, VAV: Proto-oncogene vav 0.075 0.0446
CSK CSK: Tyrosine-protein kinase CSK 0.075 0.036
JAK2 JAK2: Tyrosine-protein kinase JAK2 0.075 0.253
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.075 0.074
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.075 0.074
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 0.075 0.027
STAT6 STAT6: Signal transducer and activator of transcription 6 0.075 0.157
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.075 0.0446
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.072 0.0263
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.065 0.065
NAGPA NAGPA: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precur 0.062 0.087
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.062 0.070
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.061 0.126
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.057 0.124
FLII FLII, FLIL: Protein flightless-1 homolog 0.057 0.0446
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.057 0.157
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.057 0.0263
USP7 USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7 0.057 1.48
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.057 0.274
HCK N/A 0.057 0.472
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 0.057 0.472
LYN LYN: Tyrosine-protein kinase Lyn 0.057 0.157
NFKB2 N/A 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
C1QC C1QC, C1QG: Complement C1q subcomponent subunit C precursor 0.049 0.044
MAPK15 N/A 0.049 0.04
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.049 0.049
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.04
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.04
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.049 0.04
BIRC4 BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4 0.046 0.081
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.0453 0.0446
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.0453 0.074
JAK1 0.0453 0.124
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.0453 0.036
BMX N/A 0.0453 0.029
PLSCR1 PLSCR1: Phospholipid scramblase 1 0.0425 0.307
HLA-DRA 0.0425 0.070
GNAI3 GNAI3: Guanine nucleotide-binding protein G(k) subunit alpha 0.0425 0.087
LTB4R LTB4R, BLT, BLT1, BLTR, CMKRL1, GPR16, P2RY7: Leukotriene B4 receptor 1 0.0425 0.070
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.0425 0.026
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.0425 0.039
GNA13 GNA13: Guanine nucleotide-binding protein alpha-13 subunit 0.0425 0.026
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.0425 0.087
TBK1 TBK1, NAK: Serine/threonine-protein kinase TBK1 0.0425 0.052
GNAI2 Galphai2 protein 0.0425 0.307
LILRB1 N/A 0.0425 0.307
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.0425 0.575
MYD88 0.041 0.293
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.04 0.109
TRIM39 TRIM39, RNF23, TFP: Tripartite motif-containing protein 39 0.04 0.109
IRAK4 IRAK4: Interleukin-1 receptor-associated kinase 4 0.039 0.032
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.039 0.045
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.039 0.105
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.037 0.274
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.037 0.033
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.037 0.030
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.037 0.0446
LCP1 LCP1, PLS2: Plastin-2 0.036 0.074
PSMD12 PSMD12: 26S proteasome non-ATPase regulatory subunit 12 0.033 0.033
C1QA C1QA: Complement C1q subcomponent subunit A precursor 0.033 0.072
C2 C2: Complement C2 precursor 0.032 0.0263
ADIPOQ ADIPOQ, ACDC, ACRP30, APM1, GBP28: Adiponectin precursor 0.032 0.072
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.032 0.307
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.032 0.307
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.032 0.144
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.032 0.163
CD44 N/A 0.032 0.144
NCSTN NCSTN, KIAA0253, UNQ1874/PRO4317: Nicastrin precursor 0.032 0.087
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.032 0.144
CRLF3 N/A 0.032 0.087
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.032 0.052
ITGAE ITGAE: Integrin alpha-E precursor 0.032 0.0971
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.032 0.070
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.032 0.144
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.032 0.052
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.032 0.070
ITGA4 ITGA4, CD49D: Integrin alpha-4 precursor 0.032 0.070
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.032 0.163
CCR5 CCR5: CCR5 receptor (Fragment) 0.032 0.0425
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.032 0.052
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.032 0.144
CARD8 CARD8, KIAA0955, NDPP1: Caspase recruitment domain-containing protein 8 0.032 0.053
TRAF6 TRAF6, RNF85: TNF receptor-associated factor 6 0.032 0.251
TNFSF7 CD70, CD27L, CD27LG, TNFSF7: CD70 antigen 0.0308 0.174
TNFSF9 TNFSF9: Tumor necrosis factor ligand superfamily member 9 0.0308 0.174
IRAK3 IRAK3: Interleukin-1 receptor-associated kinase 3 0.0308 0.083
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 0.029 0.032
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.029 0.027
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.029 0.0453
CFB CFB, BF, BFD: Complement factor B precursor 0.029 0.0263
KLRD1 KLRD1, CD94: Natural killer cells antigen CD94 0.028 0.028
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.028 0.028
PTPRA N/A 0.028 0.028
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.028 0.028
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.028 0.028
KIR3DL1 N/A 0.028 0.052
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.028 0.028
NULL A1BG: Alpha-1B-glycoprotein precursor 0.028 0.052
ITGB1 N/A 0.028 0.028
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.028 0.028
SNAP23 SNAP23: Synaptosomal-associated protein 23 0.028 0.028
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.028 0.052
LAT LAT: Linker for activation of T-cells family member 1 0.028 0.028
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.028 0.028
SLC7A3 SLC7A3, ATRC3, CAT3: Cationic amino acid transporter 3 0.028 0.028
TBXA2R TBXA2R: Thromboxane A2 receptor 0.028 0.028
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.028 0.028
ATP1B1 N/A 0.028 0.028
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.028 0.028
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.028 0.028
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.028 0.028
DRD2 DRD2: D(2) dopamine receptor 0.028 0.028
CNTN4 CNTN4: Contactin-4 precursor 0.028 0.028
ZP3 ZP3, ZP3A, ZP3B, ZPC: Zona pellucida sperm-binding protein 3 precursor 0.028 0.028
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.028 0.028
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.028 0.028
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.028 0.028
PILRA PILRA: Paired immunoglobulin-like type 2 receptor alpha precursor 0.028 0.028
TREML1 TREML1, TLT1, UNQ1825/PRO3438: Trem-like transcript 1 protein precursor 0.028 0.028
AQP4 AQP4: Aquaporin-4 0.028 0.028
APP APP, A4, AD1: Amyloid beta A4 protein precursor 0.028 0.028
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.028 0.028
LAIR1 LAIR1, CD305: Leukocyte-associated immunoglobulin-like receptor 1 precursor 0.028 0.028
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.028 0.028
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.028 0.028
FGFR2 N/A 0.028 0.028
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.028 0.028
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.028 0.028
ABCC1 ABCC1, MRP, MRP1: Multidrug resistance-associated protein 1 0.028 0.028
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.028 0.028
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.028 0.028
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.028 0.052
CSF3R N/A 0.028 0.028
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.028 0.028
C2orf7 PAP21, C2orf7, UNQ833/PRO1760: Protease-associated domain-containing protein of 0.028 0.028
MUCDHL MUPCDH, MUCDHL, UNQ2781/PRO7168: Mucin and cadherin-like protein precursor 0.028 0.028
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.028 0.028
CDH6 CDH6: Cadherin-6 precursor 0.028 0.028
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.028 0.028
GNAO1 GNAO1: Guanine nucleotide-binding protein G(o) subunit alpha 1 0.028 0.028
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.028 0.028
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.028 0.028
PCDH7 N/A 0.028 0.028
GPRC5A GPRC5A, GPCR5A, RAI3, RAIG1: Retinoic acid-induced protein 3 0.028 0.028
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.028 0.028
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.028 0.028
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.028 0.028
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.028 0.028
FN1 N/A 0.028 0.028
CNTN1 CNTN1: Contactin-1 precursor 0.028 0.028
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.028 0.028
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.028 0.028
PTAFR PTAFR, PAFR: Platelet-activating factor receptor 0.028 0.028
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.028 0.028
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.028 0.028
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.028 0.028
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.028 0.028
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.028 0.028
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.028 0.028
BSG N/A 0.028 0.028
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.028 0.028
PCDHA2 PCDHA2: Protocadherin alpha 2 precursor 0.028 0.028
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.028 0.028
EDNRB EDNRB, ETRB: Endothelin B receptor precursor 0.028 0.028
SNAP25 N/A 0.028 0.028
RNF13 RNF13, RZF: RING finger protein 13 0.027 0.027
LTB LTB, TNFC, TNFSF3: Lymphotoxin-beta 0.027 0.265
TNFSF11 TNFSF11, OPGL, RANKL, TRANCE: Tumor necrosis factor ligand superfamily member 11 0.027 0.265
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.027 0.0446
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.027 0.0446
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.027 0.027
IFI35 N/A 0.027 0.0446
LPXN LPXN, LDLP: Leupaxin 0.027 0.027
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.027 0.027
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.027 0.027
KIAA1012 KIAA1012: Protein TRS85 homolog 0.027 0.036
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.027 0.036
USP10 USP10, KIAA0190: Ubiquitin carboxyl-terminal hydrolase 10 0.027 0.036
ME2 ME2: NAD-dependent malic enzyme, mitochondrial precursor 0.027 0.027
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.027 0.036
PSCD4 PSCD4, CYT4: Cytohesin-4 0.027 0.074
C5AR1 C5AR1, C5AR, C5R1: C5a anaphylatoxin chemotactic receptor 0.026 0.307
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.026 0.0425
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.026 0.026
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.026 0.052
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.026 0.070
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.026 0.026
GNA15 GNA15, GNA16: Guanine nucleotide-binding protein alpha-15 subunit 0.026 0.0425
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.026 0.026
UNC84B UNC84B, FRIGG, KIAA0668, RAB5IP, SUN2: Sad1/unc-84-like protein 2 0.026 0.052
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.026 0.070
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.026 0.052
LRRC59 LRRC59, PRO1855: Leucine-rich repeat-containing protein 59 0.026 0.026
CD7 CD7: T-cell antigen CD7 precursor 0.026 0.0425
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.026 0.0425
FPR1 FPR1: fMet-Leu-Phe receptor 0.026 0.307
ATP1B3 ATP1B3: Sodium/potassium-transporting ATPase subunit beta-3 0.026 0.032
FCGR2A FCGR2A: Fc of IgG, low affinity IIa, receptor 0.026 0.307
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.026 0.048
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.026 0.575
PTGIR PTGIR, PRIPR: Prostacyclin receptor 0.026 0.052
2.15E-3
Total Score 1.30