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Evidence of Interaction Between PSMD10 and PSMC3

The interaction score between PSMD10 and PSMC3 is 293.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

N/A

 N/A
Orthology
OrganismPSMD10 OrthologuePSMC3 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
bakers yeast YGR232W 1 YOR117W 1
  • AffinityCaptureMS

Get References From PubMed
worm Q9TZ67 1 O76371 1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 0.593
Domains Domains present in PSMD10 and PSMC3:
Domains in PSMD10Domains in PSMC3
IPR002110 Ankyrin
IPR003593 AAA ATPase
IPR003959 AAA ATPase, central region
IPR003960 AAA-protein subdomain
IPR005937 26S proteasome subunit P45

The Chi square scores for co-occurrence of domains that are present in PSMD10 and PSMC3 are listed below.

Domain 1Domain 2Chi Square
IPR002110 Ankyrin IPR003593 AAA ATPase 0.00850101

The background colour of the table refers to:

  • Blue Domain is only present in PSMD10
  • Yellow Domain is only present in PSMC3
  • Green Domain is present in both PSMD10 and PSMC3

 5.38E-3
Post-translational Modifications No PTMs were used in calculating likelihood of interaction
Localisation

Protein: PSMD10

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Cytoskeleton HPRD

Protein: PSMC3

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PSMD10 and PSMC3 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PSMD10 andPSMC3. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PSMD10 has 31 interactors and PSMC3 has 132 interactors of which there are 14 common interactors.

Common InteractorName of Common InteractorScore for PSMD10-Interactor (?)Score for PSMC3-Interactor (?)
PSMC4 PSMC4, MIP224, TBP7: 26S protease regulatory subunit 6B 6.51 32.20
PSMC5 PSMC5, SUG1: 26S protease regulatory subunit 8 1.28 6.33
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 1.28 32.60
SHFM1 SHFM1, DSS1, SHFDG1: 26 proteasome complex subunit DSS1 0.593 1.84
PSMD7 PSMD7, MOV34L: 26S proteasome non-ATPase regulatory subunit 7 0.593 0.740
PSMD2 PSMD2, TRAP2: 26S proteasome non-ATPase regulatory subunit 2 0.354 10.00
PSMD12 PSMD12: 26S proteasome non-ATPase regulatory subunit 12 0.354 0.890
PSMD11 PSMD11: 26S proteasome non-ATPase regulatory subunit 11 0.354 1.82
WDR71 WDR71, PAAF1: Proteasomal ATPase-associated factor 1 0.354 0.494
PSMD13 PSMD13: 26S proteasome non-ATPase regulatory subunit 13 0.354 1.82
PSMB2 PSMB2: Proteasome subunit beta type-2 0.354 1.10
PSMD1 PSMD1: 26S proteasome non-ATPase regulatory subunit 1 0.354 6.05
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.354 1.01
NULL N/A 0.119 0.119
0.572
Total Score 293.00