PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between GTF2A1 and GTF2B

The interaction score between GTF2A1 and GTF2B is 591.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between GTF2A1 and GTF2B = 0.03

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

1.85E-3

Orthology

Organism	GTF2A1 Orthologue		GTF2B Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
bakers yeast	YOR194C	1	YPR086W	1	GelRetardationAssay CoCrystalStructure Get References From PubMed
worm	O44625	1	O16991	1
fly	P52654	1	P29052	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.593

Domains

No domains were used in calculating likelihood of interaction

0.028

Post-translational Modifications

Protein: GTF2A1

PTM	Residue	Reference
Phosphorylation	280	PubMed, HPRD
Phosphorylation	281	PubMed, HPRD
Phosphorylation	316	PubMed, HPRD
Phosphorylation	321	PubMed, HPRD
Phosphoserine	280	PubMed, HPRD
Phosphoserine	281	PubMed, HPRD
Phosphoserine	316	PubMed, HPRD
Phosphoserine	321	PubMed, HPRD

Protein: GTF2B

PTM	Residue	Reference
Acetylation	238	PubMed, HPRD

Localisation

Protein: GTF2A1

Localisation	Reference
Nucleus	HPRD
Cytoplasm	HPRD

Protein: GTF2B

Localisation	Reference
Nucleus	HPRD
Nucleolus	HPRD

Transitive Score

The common interactors between GTF2A1 and GTF2B that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between GTF2A1 andGTF2B. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , GTF2A1 has 523 interactors and GTF2B has 1095 interactors of which there are 439 common interactors.

Common Interactor	Name of Common Interactor	Score for GTF2A1-Interactor (?)	Score for GTF2B-Interactor (?)
TBP	TBP, GTF2D1, TF2D, TFIID: TATA-box-binding protein	4.72	11.70
GTF2A2	GTF2A2, TF2A2: Transcription initiation factor IIA gamma chain	0.326	0.890
GTF2F2	N/A	0.155	0.251
PRKCE	PRKCE, PKCE: Protein kinase C epsilon type	0.114	0.040
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.114	0.086
MYST4	MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4	0.114	0.088
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.102	0.471
DAPK2	DAPK2: Death-associated protein kinase 2	0.096	0.055
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.096	0.096
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.096	0.251
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.086	0.114
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.086	0.139
MAP2K6	MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki	0.086	0.056
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.086	0.114
HSF1	HSF1, HSTF1: Heat shock factor protein 1	0.086	0.225
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.086	0.139
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.086	0.225
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.086	0.049
GSK3A	GSK3A: Glycogen synthase kinase-3 alpha	0.086	0.044
MOS	MOS: Proto-oncogene serine/threonine-protein kinase mos	0.086	0.050
MAP3K10	MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10	0.086	0.050
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.086	0.114
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.083	0.165
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.083	0.165
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.083	0.083
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.083	0.083
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.083	0.083
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.083	0.165
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.083	0.083
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.083	0.083
MAPK15	N/A	0.083	0.083
MAPKAPK5	N/A	0.083	0.083
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.083	0.083
NEK3	NEK3: Serine/threonine-protein kinase Nek3	0.077	0.062
PRKAA1	N/A	0.077	0.096
ERF	ERF: ETS domain-containing transcription factor ERF	0.077	0.191
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.077	0.127
ETV1	ETV1, ER81: ETS translocation variant 1	0.077	0.088
ROCK1	ROCK1: Rho-associated protein kinase 1	0.077	0.155
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.077	0.077
FOXJ2	FOXJ2, FHX: Forkhead box protein J2	0.077	0.251
INSL3	JAK3: Tyrosine-protein kinase JAK3	0.075	0.033
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.075	0.075
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.075	0.075
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.075	0.075
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.075	0.075
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.075	0.075
CDC2	CDC2: Cell division control protein 2 homolog	0.075	0.075
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.075	0.075
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.075	0.075
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.075	0.075
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.075	0.075
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.075	0.148
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.075	0.075
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.075	0.075
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.075	0.148
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.075	0.075
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.075	0.075
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.075	0.075
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.075	0.075
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.075	0.075
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.075	0.075
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.075	0.148
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.075	0.075
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.075	0.075
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.075	0.075
EEF2K	EEF2K: Elongation factor 2 kinase	0.075	0.025
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.075	0.075
TBPL2		0.071	0.071
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.069	0.822
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.069	0.225
MYO3A	MYO3A: Myosin IIIA	0.069	0.050
ETS1	ETS1, EWSR2: Protein C-ets-1	0.069	0.225
CDK2	CDK2: Cell division protein kinase 2	0.069	7.38
WEE1	WEE1: Wee1-like protein kinase	0.069	0.114
PSKH1	PSKH1: Serine/threonine-protein kinase H1	0.069	0.069
HIST1H1B	HIST1H1B, H1F5: Histone H1.5	0.069	0.111
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.069	0.139
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.069	0.233
CDK7	CDK7, MO15: Cell division protein kinase 7	0.069	0.188
CDK4	CDK4: Cell division protein kinase 4	0.069	0.139
HIST1H1A	HIST1H1A, H1F1: Histone H1.1	0.069	0.111
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.069	0.114
HIPK2	HIPK2: Homeodomain-interacting protein kinase 2	0.069	0.044
ELK1	ELK1: ETS domain-containing protein Elk-1	0.069	0.099
RFX1	RFX1: MHC class II regulatory factor RFX1	0.069	0.088
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.069	0.372
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.069	0.086
PCTK1	PCTK1: Serine/threonine-protein kinase PCTAIRE-1	0.069	0.049
CAMK1	CAMK1: Calcium/calmodulin-dependent protein kinase type 1	0.069	0.049
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.069	0.086
RPS6KB1	N/A	0.069	0.233
ERG	ERG: Transcriptional regulator ERG	0.062	0.123
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.062	0.210
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.062	0.127
CDKL5	N/A	0.062	0.049
ETS2	ETS2: Protein C-ets-2	0.062	0.152
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.062	0.127
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.062	0.155
MAPK4	MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4	0.062	0.062
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.062	0.260
IRF3	IRF3: Interferon regulatory factor 3	0.062	0.307
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.062	0.070
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.056	0.372
PRKG1	PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme	0.056	0.049
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.056	0.114
FOXL2	FOXL2: Forkhead box protein L2	0.056	0.088
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.056	0.225
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.056	0.275
CAMK2D	CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain	0.056	0.050
MAP3K11	MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11	0.056	0.086
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.056	0.139
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.056	0.233
MAP2K4	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k	0.056	0.086
FOXO1A	FOXO1A, FKHR: Forkhead box protein O1A	0.056	0.171
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.056	0.188
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.056	0.188
PAK4	PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4	0.056	0.049
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.056	0.114
HIST1H1D	HIST1H1D, H1F3: Histone H1.3	0.056	0.275
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.056	0.139
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.056	0.385
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.056	0.045
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.056	0.372
PRKCG	PRKCG, PKCG: Protein kinase C gamma type	0.056	0.049
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.056	0.233
ATM	ATM: Serine-protein kinase ATM	0.056	0.038
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.056	0.188
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.056	0.188
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.056	0.233
HIST1H1E	HIST1H1E, H1F4: Histone H1.4	0.056	0.275
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.056	0.188
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.056	0.372
ELF1	ELF1: ETS-related transcription factor Elf-1	0.055	0.515
GRK1	GRK1, RHOK: Rhodopsin kinase precursor	0.055	0.055
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.055	0.127
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.055	0.260
ICK	ICK, KIAA0936: Serine/threonine-protein kinase ICK	0.055	0.077
H1FX	H1FX: Histone H1x	0.055	0.416
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.055	0.127
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.055	0.127
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.055	0.210
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.052	0.032
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.049	0.155
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.049	0.049
MAP2K5	N/A	0.049	0.049
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.049	0.049
PAK7	PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7	0.049	0.050
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.049	0.046
PRKAA2	PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2	0.049	0.050
HSPB8	HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8	0.049	0.044
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.049	0.114
SGK	SGK, SGK1: Serine/threonine-protein kinase Sgk1	0.049	0.086
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.049	0.233
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	0.049	0.056
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.049	0.233
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.049	0.156
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.049	0.188
STK10	STK10: Uncharacterized protein STK10	0.049	0.188
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.049	0.188
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.049	0.233
SOS1	SOS1: Son of sevenless homolog 1	0.049	0.038
ROCK2	ROCK2, KIAA0619: Rho-associated protein kinase 2	0.044	0.040
PRKCA	PRKCA, PKCA, PRKACA: Protein kinase C alpha type	0.044	0.049
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.044	0.086
CDK5	CDK5: Cell division protein kinase 5	0.044	0.056
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.044	0.086
PAK6	PAK6, PAK5: Serine/threonine-protein kinase PAK 6	0.044	0.050
SGK3	SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3	0.044	0.114
CAMK4	CAMK4: Calcium/calmodulin-dependent protein kinase type IV	0.044	0.044
MKI67	MKI67: Antigen KI-67	0.0425	0.052
GAB1	GAB1: GRB2-associated-binding protein 1	0.0425	0.026
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.041	0.041
PRKCQ	PRKCQ, PRKCT: Protein kinase C theta type	0.041	0.033
LIMK1	LIMK1, LIMK: LIM domain kinase 1	0.041	0.029
PRKCI	PRKCI, DXS1179E: Protein kinase C iota type	0.041	0.041
FZR1	N/A	0.038	0.046
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.038	0.038
WDHD1	WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1	0.038	0.086
HDAC6	HDAC6, JM21: Histone deacetylase 6	0.038	0.043
HAND1	HAND1, EHAND: Heart- and neural crest derivatives-expressed protein 1	0.038	0.044
ZBTB7A	ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A	0.038	0.069
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.038	0.139
MGMT	MGMT: Methylated-DNA--protein-cysteine methyltransferase	0.037	0.100
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.035	0.046
AXL	AXL, UFO: Tyrosine-protein kinase receptor UFO precursor	0.034	0.034
TBK1	TBK1, NAK: Serine/threonine-protein kinase TBK1	0.033	0.032
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.033	0.032
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.033	0.040
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.033	0.111
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.033	0.0818
PRKD1	PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1	0.033	0.029
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.033	0.137
CSK	CSK: Tyrosine-protein kinase CSK	0.033	0.040
BRAF	BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase	0.033	0.051
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.033	0.040
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.033	0.040
LIMK2	LIMK2: LIM domain kinase 2	0.032	0.075
TGIF2	TGIF2: Homeobox protein TGIF2	0.032	0.070
KIAA0853	N/A	0.032	0.087
ESR1	ESR1, ESR, NR3A1: Estrogen receptor	0.032	0.110
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.032	0.052
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.032	0.052
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.032	0.096
SFRS15	SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15	0.032	0.032
CENPA	CENPA: Histone H3-like centromeric protein A	0.032	0.052
XRCC1	XRCC1: DNA-repair protein XRCC1	0.032	0.210
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.032	0.0971
TRIM16	TRIM16, EBBP: Tripartite motif-containing protein 16	0.032	0.039
HIVEP1	N/A	0.032	0.127
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.032	0.080
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.032	0.087
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.032	0.026
NFATC1	N/A	0.032	0.127
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.032	0.052
ACVR1B	ACVR1B, ACVRLK4: Activin receptor type-1B precursor	0.030	0.030
DAPK1	DAPK1, DAPK: Death-associated protein kinase 1	0.029	0.051
CSDA	CSDA, DBPA: DNA-binding protein A	0.029	0.038
BLM	BLM, RECQ2, RECQL3: Bloom syndrome protein	0.029	0.038
BNC1	BNC1, BNC: Zinc finger protein basonuclin-1	0.029	0.044
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.029	0.046
MTF1	MTF1: Metal regulatory transcription factor 1	0.029	0.139
VDR	VDR, NR1I1: Vitamin D3 receptor	0.029	0.136
H2AFX	H2AFX, H2AX: Histone H2A.x	0.029	0.063
SMCX	JARID1C, DXS1272E, SMCX, XE169: Histone demethylase JARID1C	0.029	0.097
RELA	RELA, NFKB3: Transcription factor p65	0.029	0.114
KIAA0683	DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized	0.029	0.038
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.029	0.111
CCNB1	Cyclin B1	0.029	0.372
DOK1	DOK1: Docking protein 1	0.029	0.046
SRF	SRF: Serum response factor	0.029	0.063
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.029	0.039
GGCX	GGCX, GC: Vitamin K-dependent gamma-carboxylase	0.029	0.029
MYF5	MYF5: Myogenic factor 5	0.029	0.049
SAPS3	N/A	0.029	0.063
ZNF335	ZNF335: Zinc finger protein 335	0.029	0.114
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.029	0.078
MTA1	MTA1: Metastasis-associated protein MTA1	0.029	0.114
PI4KII	PI4K2A: Phosphatidylinositol 4-kinase type 2-alpha	0.029	0.029
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.083
HES6	HES6: Transcription cofactor HES-6	0.028	0.052
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.083
SYTL4	Endocrine transmitter regulatory protein	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
SNRPB	N/A	0.028	0.028
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.028	0.028
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.083
IRF7	N/A	0.028	0.028
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.028	0.083
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.028
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.028	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.083
HDAC8	N/A	0.028	0.083
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.083
NF2	NF2, SCH: Merlin	0.028	0.028
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
KIF1B	N/A	0.028	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.028	0.083
PHLDB2	N/A	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.083
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.028	0.083
CORO6	N/A	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
C13orf8	N/A	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
PPEF1	N/A	0.028	0.083
CABLES1	N/A	0.028	0.028
DSP	DSP: Desmoplakin	0.028	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.028	0.083
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.028	0.083
C20orf18	N/A	0.028	0.052
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
RAB4A	N/A	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.028
UHRF1		0.028	0.083
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.083
CUTL1	CUTL1: Homeobox protein cut-like 1	0.028	0.028
ZNF265	N/A	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
TGFBR2	TGFBR2: TGF-beta receptor type-2 precursor	0.028	0.035
SYK	SYK: Tyrosine-protein kinase SYK	0.027	0.032
OGG1	N/A	0.027	0.027
STK39	STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase	0.026	0.029
PRKCZ	PRKCZ, PKC2: Protein kinase C zeta type	0.026	0.029
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.026	0.0425
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.026	0.210
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.026	0.070
EMD	EMD, EDMD, STA: Emerin	0.026	0.032
ZFX	ZFX: Zinc finger X-chromosomal protein	0.026	0.155
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.026	0.210
TRRAP	N/A	0.026	0.0425
KIF23	N/A	0.026	0.052
TCOF1	N/A	0.026	0.052
DEF6	DEF6, IBP: Differentially expressed in FDCP 6	0.026	0.052
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.026	0.127
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.026	0.052
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.026	0.852
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.026	0.070
ID3	ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3	0.026	0.062
WDR1	N/A	0.026	0.087
UBAP2	N/A	0.026	0.0425
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.026	0.087
PHF8	PHF8, KIAA1111, ZNF422: PHD finger protein 8	0.026	0.026
COIL	COIL, CLN80: Coilin	0.026	0.0425
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.026	0.0425
ZNF267	ZNF267: Zinc finger protein 267	0.026	0.030
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.026	0.087
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.026	0.155
CDKN1A	CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi	0.026	0.152
ESPL1	N/A	0.026	0.052
ARFGAP1	N/A	0.026	0.070
PGR	PGR, NR3C3: Progesterone receptor	0.026	0.109
DDIT3	DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3	0.026	0.062
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.026	0.052
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.026	0.077
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.025
BRD4	N/A	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.075
LMNA	LMNA, LMN1: Lamin-A/C	0.025	0.025
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.148
CAMK2A	N/A	0.025	0.025
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
SON		0.025	0.025
FLJ23436	N/A	0.025	0.025
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.025
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.025	0.148
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.025	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.025	0.148
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.075
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.025	0.025
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.025	0.075
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.025
KCTD1		0.025	0.025
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.025	0.025
SEC13L1	N/A	0.025	0.025
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.148
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.075
ATXN2L	N/A	0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.075
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
NUP98	N/A	0.025	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.025	0.148
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
NIPBL	N/A	0.025	0.025
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.148
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.025
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.047
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.148
CETN1	CETN1, CEN1, CETN: Centrin-1	0.025	0.025
RNF20		0.025	0.047
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.025	0.047
NES	N/A	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.025	0.075
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.075
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.075
HTATIP	N/A	0.025	0.025
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.025	0.075
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.047
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.025	0.075
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.075
PRKCB1	N/A	0.025	0.025
BCOR	N/A	0.025	0.025
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.047
CAMKK1	N/A	0.025	0.025
CCNT2	CCNT2: Cyclin-T2	0.025	0.148
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.047
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.025	0.075
C20orf77	N/A	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.025	0.025
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.075
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.025	0.025
TCEA1	N/A	0.025	0.025
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.025
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.025	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.047
SOX8	SOX8: Transcription factor SOX-8	0.025	0.075
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.025	0.075
TFAP4	TFAP4: Transcription factor AP-4	0.025	0.075
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
MAP2K3	N/A	0.025	0.025
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.075
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.075
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
ELMO1	N/A	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
RBL1	RBL1: Retinoblastoma-like protein 1	0.025	0.148
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
MAX	MAX: Protein max	0.025	0.047
HDAC7A	N/A	0.025	0.047
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.025	0.025
DIDO1	N/A	0.025	0.075
GRK6	N/A	0.025	0.025
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.025	0.075
GIT2	N/A	0.025	0.025
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025

0.299

Total Score

591.00