PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between HGS and CLTC

The interaction score between HGS and CLTC is 7.12E3.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

Pearson's Correlation between HGS and CLTC = 0.30

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

3.80E-3

Orthology

Organism	HGS Orthologue		CLTC Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
bakers yeast	YNR006W	1	YGL206C	1	AffinityCaptureWestern Get References From PubMed
worm	Q17796	1	P34574	1
fly	Q960X8	1	P29742	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

0.593

Domains

No domains were used in calculating likelihood of interaction

0.165

Post-translational Modifications

Protein: HGS

PTM	Residue	Reference
Phosphorylation	308	PubMed, HPRD
Phosphorylation	329	PubMed, HPRD
Phosphorylation	334	PubMed, HPRD
Phosphotyrosine	216	HPRD

Protein: CLTC

PTM	Residue	Reference
Acetylation	2	PubMed, HPRD
Phosphorylation	394	PubMed, HPRD
Phosphorylation	1477	PubMed, HPRD
Phosphorylation	1494	PubMed, HPRD
Phosphoserine	1493	HPRD
Phosphothreonine	393	HPRD

Localisation

Protein: HGS

Localisation	Reference
Endosome	HPRD
Cytoplasm	HPRD

Protein: CLTC

Localisation	Reference
Golgi	HPRD
Plasma membrane	HPRD
Cytoplasm	HPRD

Transitive Score

The common interactors between HGS and CLTC that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between HGS andCLTC. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , HGS has 1240 interactors and CLTC has 897 interactors of which there are 729 common interactors.

Common Interactor	Name of Common Interactor	Score for HGS-Interactor (?)	Score for CLTC-Interactor (?)
STAM2	STAM2: Signal transducing adapter molecule 2	36.10	0.073
STAM	STAM, STAM1: Signal transducing adapter molecule 1	14.60	0.245
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.461	0.038
PSMD4	PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4	0.461	0.188
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.425	0.046
ENTH	CLINT1, ENTH, EPN4, EPNR, KIAA0171: Clathrin interactor 1	0.364	7.57
RB1	RB1: Retinoblastoma-associated protein	0.307	0.052
STIP1	STIP1: Stress-induced-phosphoprotein 1	0.307	0.124
PHF10	N/A	0.275	0.029
EPS15	EPS15, AF1P: Epidermal growth factor receptor substrate 15	0.275	0.0818
DYNC1LI1	DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1	0.275	0.046
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.275	0.040
UBE2E3	UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3	0.245	0.032
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.241	0.029
COPE	COPE: Coatomer subunit epsilon	0.233	0.114
ATR	ATR, FRP1: Serine/threonine-protein kinase ATR	0.233	0.086
ANAPC5	ANAPC5, APC5: Anaphase-promoting complex subunit 5	0.233	0.063
NRAS	NRAS, HRAS1: GTPase NRas precursor	0.225	0.032
ADPRT	PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1	0.208	2.08
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.188	0.038
KIAA1012	KIAA1012: Protein TRS85 homolog	0.188	0.029
SMAD2	SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2	0.188	0.046
AIP	AIP, XAP2: AH receptor-interacting protein	0.188	0.035
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.181	0.032
ZFYVE16	ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16	0.171	0.038
SYTL4	Endocrine transmitter regulatory protein	0.165	0.052
UHRF1		0.165	0.028
C20orf18	N/A	0.165	0.028
RAB4A	N/A	0.165	0.028
NF2	NF2, SCH: Merlin	0.165	0.028
IRF3	IRF3: Interferon regulatory factor 3	0.163	0.026
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.155	0.155
NR3C1	NR3C1, GRL: Glucocorticoid receptor	0.155	0.155
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.152	0.028
POU2F1	POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1	0.152	0.026
GGA3	GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3	0.148	16.30
RBL1	RBL1: Retinoblastoma-like protein 1	0.148	0.025
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.148	0.025
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.146	0.038
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.146	0.046
GTF2F1	GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha	0.146	0.046
RNPS1	RNPS1, LDC2: RNA-binding protein with serine-rich domain 1	0.144	0.052
EIF3S5	N/A	0.143	0.053
GTF2B	GTF2B, TF2B, TFIIB: Transcription initiation factor IIB	0.139	0.078
CCNH	CCNH: Cyclin-H	0.139	0.038
IQGAP2	IQGAP2: Ras GTPase-activating-like protein IQGAP2	0.139	0.086
FKBP4	FKBP4: FK506-binding protein 4	0.139	0.054
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.137	0.025
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.137	0.025
ELF1	ELF1: ETS-related transcription factor Elf-1	0.132	0.032
H1FX	H1FX: Histone H1x	0.132	0.032
SKIV2L	SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti	0.129	0.029
PIK4CB	PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic,	0.129	0.029
RXRA	RXRA, NR2B1: Retinoic acid receptor RXR-alpha	0.127	0.096
YWHAQ	YWHAQ: 14-3-3 protein theta	0.124	0.0446
TOM1L1	TOM1L1, SRCASM: TOM1-like protein 1	0.123	0.063
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.118	0.038
RPA2	RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit	0.118	4.27
RPS6KB1	N/A	0.118	0.038
FNBP1	N/A	0.118	0.054
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.118	0.063
STAMBP	STAMBP, AMSH: STAM-binding protein	0.116	0.086
UTX	UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein	0.114	0.086
DNAJC7	DNAJC7, TPR2, TTC2: DnaJ homolog subfamily C member 7	0.114	0.188
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.114	0.046
STX7	STX7: Syntaxin-7	0.114	0.094
SGTA	SGTA, SGT: Small glutamine-rich tetratricopeptide repeat-containing protein A	0.114	0.071
PSMD11	PSMD11: 26S proteasome non-ATPase regulatory subunit 11	0.111	0.304
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	0.111	8.74
CSK	CSK: Tyrosine-protein kinase CSK	0.111	0.033
CDC23	CDC23: Cell division cycle protein 23 homolog	0.111	0.032
PPID	PPID, CYP40, CYPD: 40 kDa peptidyl-prolyl cis-trans isomerase	0.111	0.067
ITSN1	ITSN1, ITSN, SH3D1A: Intersectin-1	0.109	0.04
ITSN2	ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2	0.098	0.036
SNAPC4	SNAPC4, SNAP190: snRNA-activating protein complex subunit 4	0.0971	0.026
TGIF2	TGIF2: Homeobox protein TGIF2	0.0971	0.026
TERF1	TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1	0.0971	0.0425
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.091	0.046
ARHGEF6	ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6	0.090	0.027
NCK2	NCK2: Cytoplasmic protein NCK2	0.090	0.027
VAV1	VAV1, VAV: Proto-oncogene vav	0.090	0.027
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.090	0.051
TRIM28	TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta	0.087	0.0425
RBM14	RBM14, SIP: RNA-binding protein 14	0.087	0.0425
WDR1	N/A	0.087	0.080
CHD4	CHD4: Chromodomain-helicase-DNA-binding protein 4	0.087	0.052
UBAP2L	UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like	0.087	0.052
MYBBP1A	MYBBP1A, P160: Myb-binding protein 1A	0.087	0.032
DDX46	DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46	0.087	0.052
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.087	0.026
XRCC6	XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1	0.087	0.155
ARFGAP1	N/A	0.087	0.0425
TRRAP	N/A	0.087	0.026
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.087	0.029
NCOR1	NCOR1, KIAA1047: Nuclear receptor corepressor 1	0.087	0.029
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.087	0.038
CXorf9	N/A	0.087	0.035
FKBP5	FKBP5, AIG6, FKBP51: FK506-binding protein 5	0.086	0.054
CCNB1	Cyclin B1	0.086	0.063
VDR	VDR, NR1I1: Vitamin D3 receptor	0.086	0.056
ESRRA	ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1	0.086	0.069
NIPA1	NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1	0.083	0.083
COPS3	COPS3, CSN3: COP9 signalosome complex subunit 3	0.0818	0.304
CD2AP	CD2AP: CD2-associated protein	0.0818	0.067
NCK1	NCK1, NCK: Cytoplasmic protein NCK1	0.0818	0.033
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.0818	0.027
LYN	LYN: Tyrosine-protein kinase Lyn	0.0818	0.033
IQGAP1	IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1	0.0818	0.041
GTF2F2	N/A	0.080	0.032
STK16	N/A	0.080	0.032
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.080	0.026
TERF2	TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2	0.080	0.0425
E2F1	E2F1, RBBP3: Transcription factor E2F1	0.080	0.052
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.080	0.026
SKIIP	SNW1, SKIIP, SKIP: SNW domain-containing protein 1	0.078	0.063
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.078	0.038
ARPC1B	ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B	0.078	0.054
GNB1	GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1	0.078	0.087
SNRP70	SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa	0.078	0.029
SAFB	SAFB, HAP, HET, SAFB1: Scaffold attachment factor B	0.078	0.046
GNB2	GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2	0.078	0.071
SF3B4	SF3B4, SAP49: Splicing factor 3B subunit 4	0.078	0.038
PABPN1	PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2	0.078	0.046
MBD3	MBD3: Methyl-CpG-binding domain protein 3	0.078	0.029
CPSF1	CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1	0.078	0.029
UBA2	SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2	0.078	0.046
PAPOLA	PAPOLA, PAP: Poly(A) polymerase alpha	0.078	0.046
DDX41	DDX41, ABS: Probable ATP-dependent RNA helicase DDX41	0.078	0.139
YEATS2	KIAA1197, YEATS2: YEATS domain-containing protein 2	0.078	0.046
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.078	0.038
BRD2	BRD2, KIAA9001, RING3: Bromodomain-containing protein 2	0.078	0.029
SFRS4	SFRS4, SRP75: Splicing factor, arginine/serine-rich 4	0.078	0.046
NOC2L	NOC2L: Nucleolar complex protein 2 homolog	0.078	0.046
DDX3X	DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X	0.078	0.046
RBM8A	RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A	0.078	0.038
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.078	0.029
MTA1	MTA1: Metastasis-associated protein MTA1	0.078	0.029
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.078	0.038
YY1	YY1: Transcriptional repressor protein YY1	0.078	0.046
TIAL1	TIAL1: Nucleolysin TIAR	0.078	0.046
AKAP8	AKAP8, AKAP95: A-kinase anchor protein 8	0.078	0.038
EIF4G2	EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2	0.078	0.063
WBSCR1	EIF4H, KIAA0038, WBSCR1, WSCR1: Eukaryotic translation initiation factor 4H	0.078	0.063
KIAA0788	ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase	0.078	0.046
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.077	0.096
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.075	0.0263
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.075	0.046
SMAD1	SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1	0.075	0.025
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.075	0.025
WWTR1	WWTR1, TAZ: WW domain-containing transcription regulator protein 1	0.075	0.075
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.075	0.025
C10orf9	CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y	0.075	0.025
CCNT2	CCNT2: Cyclin-T2	0.075	0.025
EEF2K	EEF2K: Elongation factor 2 kinase	0.075	0.025
CCNE1	CCNE1, CCNE: G1/S-specific cyclin-E1	0.075	0.025
PSTPIP1	PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1	0.074	0.030
SLA	SLA, SLAP, SLAP1: SRC-like-adapter	0.074	0.0263
NCF1	Neutrophil cytosolic factor 1 variant (Fragment)	0.074	0.030
RDX	RDX: Radixin	0.073	0.032
HSF2	HSF2, HSTF2: Heat shock factor protein 2	0.071	0.056
MAP3K11	MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11	0.071	0.0308
UBAP2	N/A	0.070	0.0425
RBM3	RBM3, RNPL: Putative RNA-binding protein 3	0.070	0.0425
TOP2B	N/A	0.070	0.052
SMARCC2	N/A	0.070	0.032
JMJD1A	JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr	0.070	0.026
HNRPA0	HNRPA0: Heterogeneous nuclear ribonucleoprotein A0	0.070	0.052
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.070	0.080
UBTF	UBTF, UBF, UBF1: Nucleolar transcription factor 1	0.070	0.0425
RDBP	RDBP, NELFE, RD: Negative elongation factor E	0.070	0.0425
RBMX	RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G	0.070	0.052
HMGN1	HMGN1, HMG14: Non-histone chromosomal protein HMG-14	0.070	0.052
NCOA3	N/A	0.070	0.026
SMARCA4	SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4	0.070	0.0425
SREBF2	N/A	0.070	0.0425
AOF2	AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1	0.070	0.0425
DNMT1	DNMT1, AIM, DNMT: DNA	0.070	0.0425
TCOF1	N/A	0.070	0.0425
NBN	NBN, NBS, NBS1, P95: Nibrin	0.070	0.155
HMGN2	HMGN2, HMG17: Non-histone chromosomal protein HMG-17	0.070	0.052
PTMA	N/A	0.070	0.052
ZNF638	ZNF638, NP220, ZFML: Zinc finger protein 638	0.070	0.070
GNB2L1	Lung cancer oncogene 7	0.070	0.060
ABCF1	N/A	0.070	0.0425
EIF4G1	EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1	0.070	0.052
GTF3C1	N/A	0.070	0.026
MATR3	MATR3, KIAA0723: Matrin-3	0.070	0.087
SH2BP1	CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog	0.070	0.0425
PHF3	PHF3, KIAA0244: PHD finger protein 3	0.070	0.032
IKBKG	IKBKG, FIP3, NEMO: NF-kappa-B essential modulator	0.070	0.032
NR4A2	NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2	0.069	0.049
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.067	0.033
HCK	N/A	0.067	0.027
WWOX	WWOX, FOR, WOX1: WW domain-containing oxidoreductase	0.067	0.033
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.067	0.054
CRKL	CRKL: Crk-like protein	0.067	0.090
BRAF	BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase	0.067	0.067
PLCB3	PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3	0.067	0.033
EPS15L1	EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1	0.065	0.064
RIMS1	RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos	0.065	0.027
EIF3S9	EIF3S9: Eukaryotic translation initiation factor 3 subunit 9	0.063	0.063
POLR2A	POLR2A: Uncharacterized protein POLR2A	0.063	0.029
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.063	0.029
SFRS2	SFRS2: Splicing factor, arginine/serine-rich 2	0.063	0.063
BAZ2A	BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A	0.063	0.029
IEF-SSP-9502	PWP1: Periodic tryptophan protein 1 homolog	0.063	0.087
HIRA	HIRA, DGCR1, HIR, TUPLE1: Protein HIRA	0.063	0.087
EP300	N/A	0.063	0.038
CBX3	CBX3: Chromobox protein homolog 3	0.063	0.063
CUL5	CUL5, VACM1: Cullin-5	0.063	0.139
VDP	DKFZp451D234: Putative uncharacterized protein DKFZp451D234	0.063	0.056
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.063	0.038
SNRPD3	SNRPD3: Small nuclear ribonucleoprotein Sm D3	0.063	0.063
TOPORS	TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors	0.063	0.029
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.063	0.038
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.063	0.046
STAG2	STAG2, SA2: Cohesin subunit SA-2	0.063	0.046
SP3	SP3: Transcription factor Sp3	0.063	0.038
MYH9	MYH9: Myosin-9	0.063	0.029
GOLGA5	GOLGA5, RETII, RFG5: Golgin subfamily A member 5	0.063	0.056
CGI-48	UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho	0.063	0.087
TOPBP1	TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1	0.063	0.087
GSK3B	N/A	0.063	0.029
PPP1R12A	PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A	0.063	0.038
HDAC3	HDAC3: Histone deacetylase 3	0.063	0.063
ZNF330	ZNF330, NOA36: Zinc finger protein 330	0.063	0.038
SNRPC	SNRPC: U1 small nuclear ribonucleoprotein C	0.063	0.046
RBM15	RBM15, OTT: Putative RNA-binding protein 15	0.063	0.038
PABPC1	PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1	0.063	0.029
MTF1	MTF1: Metal regulatory transcription factor 1	0.063	0.029
NAP1L1	NAP1L1, NRP: Nucleosome assembly protein 1-like 1	0.063	0.029
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.063	0.038
HNRPF	HNRPF: Heterogeneous nuclear ribonucleoprotein F	0.063	0.046
AGTPBP1	AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein	0.063	0.029
FKBP1A	FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A	0.063	0.038
ZCCHC8	ZCCHC8: Zinc finger CCHC domain-containing protein 8	0.063	0.139
SF3B1	SF3B1, SAP155: Splicing factor 3B subunit 1	0.063	0.086
CSPG6	SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3	0.063	0.063
ELMO2	ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2	0.063	0.069
HDAC1	HDAC1, RPD3L1: Histone deacetylase 1	0.063	0.038
SPEN	SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein	0.063	0.029
SFRS1	SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1	0.063	0.063
ZNF24	ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24	0.063	0.038
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.063	0.038
ELAVL1	ELAVL1, HUR: ELAV-like protein 1	0.063	0.038
BTAF1	BTAF1, TAF172: TATA-binding protein-associated factor 172	0.063	0.114
DAXX	DAXX, BING2, DAP6: Death domain-associated protein 6	0.063	0.029
SYNCRIP	SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q	0.063	0.046
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.063	0.063
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.063	0.038
HDAC2	HDAC2: Histone deacetylase 2	0.063	0.078
SFRS5	SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5	0.063	0.029
COPA	COPA: Coatomer subunit alpha	0.063	0.118
SUZ12	SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12	0.063	0.063
DDX5	DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5	0.063	0.029
SFRS10	SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10	0.063	0.046
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.063	0.038
ACIN1	ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus	0.063	0.038
FHOD1	FHOD1, FHOS, FHOS1: FH1/FH2 domain-containing protein 1	0.063	0.069
PPP1R8	N/A	0.063	0.139
SSB	SSB: Lupus La protein	0.063	0.078
SFRS6	SFRS6, SRP55: Splicing factor, arginine/serine-rich 6	0.063	0.038
TDG	TDG: G/T mismatch-specific thymine DNA glycosylase	0.063	0.063
DICER1	DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer	0.063	0.038
DHX16	DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN	0.063	0.029
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.063	0.063
EIF2B5	EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon	0.063	0.038
NOL1	N/A	0.063	0.038
SNRPB2	SNRPB2: U2 small nuclear ribonucleoprotein B''	0.063	0.063
PPARA	PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha	0.062	0.062
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.062	0.127
PLEKHA5	PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member	0.062	0.077
YAP1	YAP1, YAP65: 65 kDa Yes-associated protein	0.062	0.055
PLCG1	PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1	0.061	0.030
ERF	ERF: ETS domain-containing transcription factor ERF	0.060	0.026
MYB	MYB: Myb proto-oncogene protein	0.060	0.026
TERF2IP	TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1	0.060	0.132
BAG3	BAG3, BIS: BAG family molecular chaperone regulator 3	0.056	0.049
NR5A1	NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1	0.056	0.069
STX1A	STX1A, STX1: Syntaxin-1A	0.056	0.057
ESR1	ESR1, ESR, NR3A1: Estrogen receptor	0.056	0.049
NEDD4L	NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein	0.055	0.096
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.054	0.038
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.054	0.038
MYBL2	MYBL2, BMYB: Myb-related protein B	0.054	0.063
CDC6	CDC6, CDC18L: Cell division control protein 6 homolog	0.054	0.046
RIN1	RIN1: Ras and Rab interactor 1	0.054	0.029
ORC1L	ORC1L, ORC1, PARC1: Origin recognition complex subunit 1	0.054	0.046
MAPK15	N/A	0.052	0.028
FOXM1	FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1	0.052	0.028
KIAA1443	HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez	0.052	0.028
ELF2	ELF2, NERF: ETS-related transcription factor Elf-2	0.052	0.028
PPEF1	N/A	0.052	0.083
HTATIP	HTATIP, TIP60: Histone acetyltransferase HTATIP	0.052	0.028
ZHX1	ZHX1: Zinc fingers and homeoboxes protein 1	0.052	0.028
CUTL1	CUTL1: Homeobox protein cut-like 1	0.052	0.028
KIAA0853	N/A	0.052	0.0425
CHUK	N/A	0.052	0.0425
RGS14	N/A	0.052	0.026
ZNF148	ZNF148, ZBP89: Zinc finger protein 148	0.052	0.0425
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.052	0.032
DDX21	DDX21: Nucleolar RNA helicase 2	0.052	0.052
TP53BP1	TP53BP1: Tumor suppressor p53-binding protein 1	0.052	0.060
IFI16	N/A	0.052	0.032
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.052	0.032
FNBP4	FNBP4, FBP30, KIAA1014: Formin-binding protein 4	0.052	0.026
MECP2	MECP2: Methyl-CpG-binding protein 2	0.052	0.032
EIF5AP1	EIF5A: Eukaryotic translation initiation factor 5A-1	0.052	0.0425
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.052	0.087
ROCK1	ROCK1: Rho-associated protein kinase 1	0.052	0.026
XRCC1	XRCC1: DNA-repair protein XRCC1	0.052	0.0971
EMD	EMD, EDMD, STA: Emerin	0.052	0.032
ZNF267	ZNF267: Zinc finger protein 267	0.052	0.032
CDKN2D	CDKN2D: Cyclin-dependent kinase 4 inhibitor D	0.052	0.0425
PLEK	PLEK, P47: Pleckstrin	0.052	0.032
NUP214	N/A	0.052	0.039
SET	SET: Protein SET	0.052	0.052
MEF2A	N/A	0.052	0.127
EPN1	EPN1: Epsin-1	0.051	0.051
SORBS3	SORBS3, SCAM1: Vinexin	0.051	0.027
PGR	PGR, NR3C3: Progesterone receptor	0.049	0.055
NFIB	N/A	0.049	0.026
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	0.049	0.04
ABI1	ABI1, SSH3BP1: Abl interactor 1	0.049	0.109
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	0.049	0.04
NR1D1	NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1	0.049	0.056
NR4A1	CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor	0.049	0.050
PPARG	CREB3L2-PPARgamma	0.049	0.056
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.048	0.026
HIST1H1C	HIST1H1C, H1F2: Histone H1.2	0.047	0.025
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.047	0.025
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.047	0.047
HOXA10	HOXA10, HOX1H: Homeobox protein Hox-A10	0.047	0.025
DLX3	DLX3: Homeobox protein DLX-3	0.047	0.025
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.047	0.025
FARSLA	FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain	0.047	0.025
ISL2	ISL2: Insulin gene enhancer protein ISL-2	0.047	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.047	0.025
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.047	0.025
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.047	0.025
CETN1	CETN1, CEN1, CETN: Centrin-1	0.047	0.025
PSMD1	PSMD1: 26S proteasome non-ATPase regulatory subunit 1	0.046	0.822
ERCC3	ERCC3, XPB, XPBC: TFIIH basal transcription factor complex helicase XPB subunit	0.046	0.038
MDN1	MDN1, KIAA0301: Midasin	0.046	0.114
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.046	0.046
DDX51	DDX51: ATP-dependent RNA helicase DDX51	0.046	0.029
SSRP1	SSRP1, FACT80: FACT complex subunit SSRP1	0.046	0.078
SYMPK	SYMPK, SPK: Symplekin	0.046	0.029
SNRPD1	SNRPD1: Small nuclear ribonucleoprotein Sm D1	0.046	0.063
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.046	0.087
SMARCA5	SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul	0.046	0.063
EDD1	EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1	0.046	0.035
CSTF1	CSTF1: Cleavage stimulation factor 50 kDa subunit	0.046	0.071
CTDP1	CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase	0.046	0.054
ARFGEF2	ARFGEF2, ARFGEP2, BIG2: Brefeldin A-inhibited guanine nucleotide-exchange protei	0.046	0.046
SRF	SRF: Serum response factor	0.046	0.114
MSH6	MSH6, GTBP: DNA mismatch repair protein MSH6	0.046	0.046
SMC1L1	SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos	0.046	0.063
DDX24	DDX24: ATP-dependent RNA helicase DDX24	0.046	0.038
ATF1	ATF1: Cyclic AMP-dependent transcription factor ATF-1	0.046	0.046
NUP153	N/A	0.046	0.063
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.046	0.063
CLASP1	CLASP1, KIAA0622, MAST1: CLIP-associating protein 1	0.046	0.114
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.046	0.086
PABPC4	PABPC4, APP1, PABP4: Polyadenylate-binding protein 4	0.046	0.046
YARS	YARS: Tyrosyl-tRNA synthetase, cytoplasmic	0.046	0.046
MCM3	MCM3: DNA replication licensing factor MCM3	0.046	0.046
SND1	SND1, TDRD11: Staphylococcal nuclease domain-containing protein 1	0.046	0.046
COPB2	COPB2: Coatomer subunit beta'	0.046	0.146
KLHDC4	N/A	0.046	0.029
ANP32B	ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb	0.046	0.063
EIF2S1	EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1	0.046	0.078
SGK3	SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3	0.046	0.029
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.046	0.029
CUL4B	N/A	0.046	0.038
LIG1	LIG1: DNA ligase 1	0.046	0.046
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.046	0.038
CORO1C	CORO1C, CRNN4: Coronin-1C	0.046	0.087
ARMET	ARMET, ARP: Protein ARMET precursor	0.046	0.029
EIF2S2	EIF2S2, EIF2B: Eukaryotic translation initiation factor 2 subunit 2	0.046	0.078
WDR44	WDR44: WD repeat-containing protein 44	0.046	0.038
LSM2	LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2	0.046	0.038
CSTF2T	CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant	0.046	0.046
HIF1A	HIF1A, MOP1: Hypoxia-inducible factor 1 alpha	0.046	0.046
SAPS3	N/A	0.046	0.038
FZR1	N/A	0.046	0.038
TP53	TP53, P53: Cellular tumor antigen p53	0.046	0.139
EIF3S2	EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2	0.046	0.118
UNG	N/A	0.046	0.038
AKAP8L	AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like	0.046	0.046
YBX1	YBX1, NSEP1, YB1: Nuclease sensitive element-binding protein 1	0.046	0.063
RBMX2	RBMX2, CGI-79: RNA-binding motif protein, X-linked 2	0.046	0.029
SEC31L1	N/A	0.046	0.087
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.046	0.037
PSMD14	PSMD14, POH1: 26S proteasome non-ATPase regulatory subunit 14	0.046	0.046
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.0453	0.037
GGA1	GGA1: GGA1 protein	0.044	0.372
SPAG1	SPAG1: Sperm-associated antigen 1	0.044	0.049
FYN	FYN: Proto-oncogene tyrosine-protein kinase Fyn	0.044	0.036
SH3KBP1	SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1	0.044	0.036
GRB2	GRB2, ASH: Growth factor receptor-bound protein 2	0.044	0.036
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	0.044	0.036
PRKCA	PRKCA, PKCA, PRKACA: Protein kinase C alpha type	0.043	0.043
FOXO3A	FOXO3A, FKHRL1: Forkhead box protein O3A	0.043	0.046
IRS2	IRS2: Insulin receptor substrate 2	0.0425	0.026
API5	N/A	0.0425	0.070
SAT	SAT1, SAT: Diamine acetyltransferase 1	0.0425	0.026
STRN3	STRN3, GS2NA, SG2NA: Striatin-3	0.0425	0.032
CENPA	CENPA: Histone H3-like centromeric protein A	0.0425	0.052
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.0425	0.032
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.0425	0.070
AFF1	N/A	0.0425	0.0425
USP24	USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24	0.0425	0.052
BATF	BATF: Basic leucine zipper transcriptional factor ATF-like	0.0425	0.032
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.0425	0.0425
ZNF318	ZNF318, HRIHFB2436: Zinc finger protein 318	0.0425	0.032
BAZ1B	BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain	0.0425	0.070
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.0425	0.026
TRAFD1	TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1	0.0425	0.026
VIM	VIM: Vimentin	0.0425	0.026
TOP2A	TOP2A, TOP2: DNA topoisomerase 2-alpha	0.0425	0.416
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.0425	0.0425
GAB2	N/A	0.0425	0.032
VCPIP1	VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135	0.0425	0.026
SP100	N/A	0.0425	0.032
RBM6	RBM6, DEF3: RNA-binding protein 6	0.0425	0.026
RFXDC2	RFXDC2: Regulatory factor X domain-containing protein 2.	0.0425	0.032
AP2B1	AP2B1: Uncharacterized protein AP2B1	0.0425	0.173
HIVEP1	N/A	0.0425	0.032
CALM2	CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca	0.041	0.032
YWHAE	YWHAE: 14-3-3 protein epsilon	0.041	0.040
ARHGAP12	ARHGAP12: Rho GTPase-activating protein 12	0.041	0.041
SLA2	SLA2, C20orf156, SLAP2: Src-like-adapter 2	0.04	0.04
AMPH	AMPH, AMPH1: Amphiphysin	0.04	0.04
HNRPK	N/A	0.040	0.032
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.040	0.067
VCP	VCP: Transitional endoplasmic reticulum ATPase	0.040	0.032
CARS	CARS: Cysteinyl-tRNA synthetase, cytoplasmic	0.040	0.032
EIF3S8	EIF3S8: Eukaryotic translation initiation factor 3 subunit 8	0.040	0.181
CBLC	CBLC, CBL3, RNF57: Signal transduction protein CBL-C	0.039	0.026
TCF3	TCF3, E2A, ITF1: Transcription factor E2-alpha	0.038	0.046
RANBP9	RANBP9, RANBPM: Ran-binding protein 9	0.038	0.029
CDK4	CDK4: Cell division protein kinase 4	0.038	0.046
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.038	0.063
CDK2	CDK2: Cell division protein kinase 2	0.038	0.046
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.038	0.129
LMNB1	LMNB1, LMN2, LMNB: Lamin-B1	0.038	0.046
HMGB2	HMGB2, HMG2: High mobility group protein B2	0.038	0.063
BCDO2	PTS: 6-pyruvoyl tetrahydrobiopterin synthase	0.038	0.118
BARD1	BARD1: BRCA1-associated RING domain protein 1	0.038	0.071
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.038	0.129
H2AFX	H2AFX, H2AX: Histone H2A.x	0.038	0.078
PAK1IP1	PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1	0.038	0.087
KLF13	KLF13, BTEB3, NSLP1: Krueppel-like factor 13	0.038	0.038
NPM1	NPM1, NPM: Nucleophosmin	0.038	0.046
RBM7		0.038	0.046
CDK7	CDK7, MO15: Cell division protein kinase 7	0.038	0.046
POLA2	POLA2: DNA polymerase subunit alpha B	0.038	0.046
SMARCA3	HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor	0.038	0.046
EIF4G3	EIF4G3: Eukaryotic translation initiation factor 4 gamma 3	0.038	0.038
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.038	0.046
MCM2	MCM2, BM28, CCNL1, CDCL1, KIAA0030: DNA replication licensing factor MCM2	0.038	0.063
MRE11A	MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A	0.038	0.054
PCNA	PCNA: Proliferating cell nuclear antigen	0.038	0.063
WRN	WRN, RECQ3, RECQL2: Werner syndrome ATP-dependent helicase	0.038	0.046
TSC1	TSC1, KIAA0243, TSC: Hamartin	0.038	0.038
MAFG	MAFG: Transcription factor MafG	0.038	0.063
HTATSF1	HTATSF1: HIV Tat-specific factor 1	0.038	0.046
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	0.038	0.086
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.038	0.078
NFE2L2	NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2	0.038	0.038
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.038	0.071
MAD2L1	MAD2L1, MAD2: Mitotic spindle assembly checkpoint protein MAD2A	0.038	0.038
SPTA1	SPTA1, SPTA: Spectrin alpha chain, erythrocyte	0.037	0.074
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.037	0.0263
GGA2	GGA2, KIAA1080: ADP-ribosylation factor-binding protein GGA2	0.036	0.521
IPO7	IPO7: Uncharacterized protein IPO7	0.036	0.091
RANGAP1	RANGAP1, SD: Ran GTPase-activating protein 1	0.036	0.036
BIN1	BIN1, AMPHL: Myc box-dependent-interacting protein 1	0.036	0.036
BAIAP2	BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2	0.036	0.036
NEDD9	NEDD9, CASL: Enhancer of filamentation 1	0.036	0.036
RASA1	RASA1, RASA: Ras GTPase-activating protein 1	0.036	0.036
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.035	0.028
YES1	YES1, YES: Proto-oncogene tyrosine-protein kinase Yes	0.033	0.033
FKBP8	DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment)	0.033	0.067
SH3BP3		0.032	0.060
ESPL1	N/A	0.032	0.052
KIF23	N/A	0.032	0.052
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.032	0.052
DRIM	UTP20, DRIM: Small subunit processome component 20 homolog	0.032	0.077
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.032	0.070
CEP170	CEP170, FAM68A, KAB, KIAA0470: Centrosomal protein of 170 kDa	0.032	0.0425
MKI67	MKI67: Antigen KI-67	0.032	0.155
CDKN1A	CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi	0.032	0.032
MAPK8IP3	MAPK8IP3, JIP3, KIAA1066: C-jun-amino-terminal kinase-interacting protein 3	0.032	0.026
USP7	USP7, HAUSP: Ubiquitin carboxyl-terminal hydrolase 7	0.032	0.032
PPIA	PPIA, CYPA: Peptidyl-prolyl cis-trans isomerase A	0.032	0.032
TXNL1	TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1	0.032	0.137
EEF1G	EEF1G, EF1G, PRO1608: Elongation factor 1-gamma	0.032	0.051
DNAJA1	DNAJA1, DNAJ2, HDJ2, HSJ2, HSPF4: DnaJ homolog subfamily A member 1	0.032	0.156
WAS	WAS, IMD2: Wiskott-Aldrich syndrome protein	0.032	2.53
EIF3S6	EIF3S6, INT6: Eukaryotic translation initiation factor 3 subunit 6	0.032	0.148
XPO1	XPO1, CRM1: Exportin-1	0.032	0.111
PDIA3	PDIA3, ERP57, ERP60, GRP58: Protein disulfide-isomerase A3 precursor	0.032	0.046
CCT4	CCT4, CCTD, SRB: T-complex protein 1 subunit delta	0.032	0.032
TXNDC	TXNDC1, TMX, PSEC0085, TXNDC, UNQ235/PRO268: Thioredoxin domain-containing prote	0.032	0.056
PSMC1	PSMC1: 26S protease regulatory subunit 4	0.032	0.040
PSMA2	PSMA2, PSC3: Proteasome subunit alpha type-2	0.032	0.032
PSMC2	PSMC2, MSS1: 26S protease regulatory subunit 7	0.032	0.066
PSMB7	PSMB7: Proteasome subunit beta type-7 precursor	0.032	0.040
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.032	0.032
MAP3K10	MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10	0.0308	0.0308
SNAP23	SNAP23: Synaptosomal-associated protein 23	0.030	0.062
SPTAN1	N/A	0.030	0.037
FRK	FRK, PTK5, RAK: Tyrosine-protein kinase FRK	0.029	0.033
CTTN	CTTN, EMS1: Src substrate cortactin	0.029	2.20
SLC4A1AP	SLC4A1AP: Uncharacterized protein SLC4A1AP	0.029	0.086
R3HDM1	R3HDM1, KIAA0029, R3HDM: R3H domain-containing protein 1	0.029	0.038
CDC20	CDC20: Cell division cycle protein 20 homolog	0.029	0.118
DYNC1I2	N/A	0.029	0.118
PCTK1	PCTK1: Serine/threonine-protein kinase PCTAIRE-1	0.029	0.029
REXO2	REXO2, SFN, CGI-114, SMFN: Oligoribonuclease, mitochondrial precursor	0.029	0.063
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.029	0.038
MEF2D	MEF2D: Myocyte-specific enhancer factor 2D	0.029	0.069
EML4	EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4	0.029	0.0308
BRCA1	BRCA1, RNF53: Breast cancer type 1 susceptibility protein	0.029	0.071
EXOSC2	EXOSC2, RRP4: Exosome complex exonuclease RRP4	0.029	0.029
HDGF	HDGF, HMG1L2: Hepatoma-derived growth factor	0.029	0.078
CSDA	CSDA, DBPA: DNA-binding protein A	0.029	0.029
CDK5	CDK5: Cell division protein kinase 5	0.029	3.67
MAP2K4	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k	0.029	0.063
SIPA1L1	SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein	0.029	0.029
MCM4	MCM4, CDC21: DNA replication licensing factor MCM4	0.029	0.063
WEE1	WEE1: Wee1-like protein kinase	0.029	0.029
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.029	0.046
CHAF1B	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B	0.029	0.087
KIF11	N/A	0.029	0.046
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.029	0.029
PI4KII	PI4K2A: Phosphatidylinositol 4-kinase type 2-alpha	0.029	0.038
LOC642558	FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1	0.028	0.028
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.028	0.083
C13orf8	N/A	0.028	0.028
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.028	0.052
POGZ	POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain	0.028	0.028
PTBP1	PTBP1: Polypyrimidine tract binding protein 1	0.028	0.028
HES6	HES6: Transcription cofactor HES-6	0.028	0.028
DSP	DSP: Desmoplakin	0.028	0.028
BID	BID: BH3-interacting domain death agonist	0.028	0.028
KIF1B	N/A	0.028	0.028
NSBP1	NSBP1: Nucleosome-binding protein 1	0.028	0.028
MAPKAPK5	N/A	0.028	0.028
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
HDAC8	N/A	0.028	0.028
ZCCHC3	ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3	0.028	0.083
ZNF295	ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295	0.028	0.028
ZNF579	ZNF579: Zinc finger protein 579	0.028	0.028
ILF3	ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3	0.028	0.028
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.028	0.083
C14orf151	C14orf151: Uncharacterized protein C14orf151 (Fragment)	0.028	0.028
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.028	0.028
ZNF644	ZNF644, KIAA1221, ZEP2: Zinc finger protein 644	0.028	0.028
NFIA	NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A	0.028	0.028
AR	AR, DHTR, NR3C4: Androgen receptor	0.028	0.028
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.028	0.028
MLL2	MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2	0.028	0.028
HNRPC	HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2	0.028	0.028
WDR54	N/A	0.028	0.052
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
DUSP15	N/A	0.028	0.028
FLJ21816	PALB2, FANCN: Partner and localizer of BRCA2	0.028	0.028
CORO6	N/A	0.028	0.028
DKFZp434K1815	DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815	0.028	0.028
SNRPB	N/A	0.028	0.028
SMARCAD1	SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator	0.028	0.028
ZNF265	N/A	0.028	0.028
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.028	0.028
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.028
CBFA2T2	CBFA2T2, EHT, MTGR1: Protein CBFA2T2	0.028	0.028
JDP2	jdp2, JDP2: Jun dimerization protein 2	0.028	0.028
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
PHLDB2	N/A	0.028	0.028
MITF	MITF: Microphthalmia-associated transcription factor	0.028	0.028
ATXN2L	ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein	0.028	0.028
TMPO	TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha	0.028	0.028
NFATC3	NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3	0.028	0.028
IRF7	N/A	0.028	0.028
NFATC2	NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2	0.028	0.028
ZFP91	ZFP91, FKSG11: Zinc finger protein 91 homolog	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.028	0.028
TCF20	TCF20, KIAA0292, SPBP: Transcription factor 20	0.028	0.028
TLE3	TLE3, KIAA1547: Transducin-like enhancer protein 3	0.028	0.083
ARNT	ARNT: Aryl hydrocarbon receptor nuclear translocator	0.028	0.028
ZC3HAV1	ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1	0.028	0.028
RAVER1	RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1	0.028	0.028
CABLES1	N/A	0.028	0.028
MAPK8IP1	MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1	0.028	0.035
MNAR	PELP1, HMX3, MNAR: Proline-, glutamic acid- and leucine-rich protein 1	0.027	0.057
HD	HD, IT15: Huntingtin	0.027	0.075
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.027	0.027
FTH1	FTH1, FTH, OK/SW-cl.84, FTHL6, PIG15: Ferritin heavy chain	0.027	0.027
TUBB3	TUBB3, TUBB4: Tubulin beta-3 chain	0.026	0.0425
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.026	0.032
KIF1C	N/A	0.026	0.026
XRCC4	N/A	0.026	0.026
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.026	0.032
FAM65A	FAM65A, KIAA1930: Protein FAM65A	0.026	0.032
ZFX	ZFX: Zinc finger X-chromosomal protein	0.026	0.026
REST	REST, NRSF, XBR: RE1-silencing transcription factor	0.026	0.026
TCF7L2	N/A	0.026	0.026
HNRPD	HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0	0.025	0.025
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.025	0.025
C20orf77	N/A	0.025	0.025
TCEA1	N/A	0.025	0.025
RNF113A	RNF113A, RNF113, ZNF183: RING finger protein 113A	0.025	0.025
BCOR	N/A	0.025	0.025
MIER1	MIER1, KIAA1610: Mesoderm induction early response protein 1	0.025	0.025
EXO1	EXO1, EXOI, HEX1: Exonuclease 1	0.025	0.025
NHN1	NHN1: Conserved nuclear protein NHN1	0.025	0.025
SAP14	SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14	0.025	0.025
GATAD2B	GATAD2B, KIAA1150: Transcriptional repressor p66 beta	0.025	0.025
PHF16	PHF16, JADE3, KIAA0215: Protein Jade-3	0.025	0.025
NCOA3	NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3	0.025	0.025
ATRX	ATRX, RAD54L, XH2: Transcriptional regulator ATRX	0.025	0.025
NEDD4	NEDD4: Uncharacterized protein NEDD4	0.025	1.33
C14orf4	C14orf4, KIAA1865, My039: RING finger protein C14orf4	0.025	0.025
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.025	0.025
SMARCA2	SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2	0.025	0.025
POLR1C	POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1	0.025	0.025
RBM10	RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10	0.025	0.025
ARID4A	ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A	0.025	0.025
KCTD1		0.025	0.025
raptor	RAPTOR, KIAA1303: Regulatory-associated protein of mTOR	0.025	0.075
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.025	0.025
MAPK8IP3	N/A	0.025	0.025
OSR1	OSR1, ODD: Protein odd-skipped-related 1	0.025	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.025
TSC2	TSC2, TSC4: Tuberin	0.025	0.044
TRERF1	TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
GRK6	N/A	0.025	0.025
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.025	0.025
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.025	0.025
EDF1	EDF1: Endothelial differentiation-related factor 1	0.025	0.025
TIA1	TIA1: Nucleolysin TIA-1 isoform p40	0.025	0.025
TFAP4	TFAP4: Transcription factor AP-4	0.025	0.025
FAF1	FAF1, CGI-03: FAS-associated factor 1	0.025	0.025
PRKCB1	N/A	0.025	0.025
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.025	0.025
GEMIN5	GEMIN5: Gem-associated protein 5	0.025	0.047
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.025	0.025
IWS1	IWS1, IWS1L: IWS1 homolog	0.025	0.025
GIT2	N/A	0.025	0.025
DIDO1	N/A	0.025	0.025
NUP98	N/A	0.025	0.025
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.025	0.025
SOX8	SOX8: Transcription factor SOX-8	0.025	0.025
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.025	0.025
TAL2	TAL2: T-cell acute lymphocytic leukemia protein 2	0.025	0.025
SMU1	SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog	0.025	0.047
NIPBL	N/A	0.025	0.075
BUB3	BUB3: Mitotic checkpoint protein BUB3	0.025	0.047
BRD4	N/A	0.025	0.025
REXO1	REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog	0.025	0.025
PSIP1	PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein	0.025	0.025
RBBP6	RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6	0.025	0.025
SEC13L1	N/A	0.025	0.025
ELMO1	N/A	0.025	0.075
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.025	0.025
CREB1	CREB1: cAMP response element-binding protein	0.025	0.025
MKI67IP	MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein	0.025	0.025
ZNF174	ZNF174, ZSCAN8: Zinc finger protein 174	0.025	0.025
CAMKK1	N/A	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.025	0.075
SFRS9	SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9	0.025	0.025
CDC2	CDC2: Cell division control protein 2 homolog	0.025	0.025
MAP2K3	N/A	0.025	0.025
ZNF598	ZNF598: Zinc finger protein 598	0.025	0.025
FLJ40432	FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227	0.025	0.025
PURB	PURB: Transcriptional activator protein Pur-beta	0.025	0.025
DHX8	DHX8, DDX8: ATP-dependent RNA helicase DHX8	0.025	0.025
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.025	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.025	0.025
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
MLXIPL	MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein	0.025	0.025
HNRPA2B1	HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1	0.025	0.025
NFYA	NFYA: Nuclear transcription factor Y subunit alpha	0.025	0.025
RNF20		0.025	0.075
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.025	0.025
HIST3H2A	HIST3H2A: Histone H2A type 3	0.025	0.025
HNRPM	HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M	0.025	0.025
MSL3L1	MSL3L1: Male-specific lethal 3-like 1	0.025	0.025
FLJ23436	N/A	0.025	0.025
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.025	0.025
RFFL	RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin	0.025	0.025
LMNA	LMNA, LMN1: Lamin-A/C	0.025	0.025
SYAP1	SYAP1, PRO3113: Synapse-associated protein 1	0.025	0.025
HDAC7A	N/A	0.025	0.025
HNRPUL1	HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1	0.025	0.025
MAX	MAX: Protein max	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
SMN2	SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein	0.025	0.025
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.025	0.025
SETD3	SETD3, C14orf154: SET domain-containing protein 3	0.025	0.025
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.025	0.025
CAMK2A	N/A	0.025	0.025
ZFPM1	ZFPM1, FOG1: Zinc finger protein ZFPM1	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
ATXN2L	N/A	0.025	0.025
HEXIM2	HEXIM2, L3: Protein HEXIM2	0.025	0.025
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.025	0.025
SSBP4	SSBP4: Single-stranded DNA-binding protein 4	0.025	0.025
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.025	0.025
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.025	0.025
DDX20	DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20	0.025	0.025
NES	N/A	0.025	0.025
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.025	0.025
SON		0.025	0.025
MLL4	WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7	0.025	0.025
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
NSUN2	NSUN2, SAKI, TRM4: tRNA	0.025	0.025
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.075
PRDM2	PRDM2, RIZ: PR domain zinc finger protein 2	0.025	0.025
HTATIP	N/A	0.025	0.025

0.299

Total Score

7.12E3