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Evidence of Interaction Between FOSL2 and JUNB

The interaction score between FOSL2 and JUNB is 905.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between FOSL2 and JUNB = 0.42

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

4.62E-3
Orthology
OrganismFOSL2 OrthologueJUNB OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
human IPI00295556 0.211 IPI00289547 0.274
  • InVitro

Get References From PubMed

fly Q8MRE5 0.211 P18289 0.186

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

1.07
Domains Domains present in FOSL2 and JUNB:
Domains in FOSL2Domains in JUNB
IPR004827 Basic-leucine zipper (bZIP) transcription factor
IPR008917 Eukaryotic transcription factor, DNA-binding
IPR000837 Fos transforming protein
IPR011700 bZIP_2.
IPR004827 Basic-leucine zipper (bZIP) transcription factor
IPR008917 Eukaryotic transcription factor, DNA-binding
IPR002112 Transcription factor Jun
IPR005643 Jun-like transcription factor
IPR011616 bZIP_1.

The Chi square scores for co-occurrence of domains that are present in FOSL2 and JUNB are listed below.

Domain 1Domain 2Chi Square
IPR004827 Basic-leucine zipper (bZIP) transcription factor IPR004827 Basic-leucine zipper (bZIP) transcription factor 485.005
IPR004827 Basic-leucine zipper (bZIP) transcription factor IPR008917 Eukaryotic transcription factor, DNA-binding 470.009
IPR004827 Basic-leucine zipper (bZIP) transcription factor IPR011616 bZIP_1. 464.114
IPR000837 Fos transforming protein IPR005643 Jun-like transcription factor 449.535
IPR000837 Fos transforming protein IPR002112 Transcription factor Jun 449.535
IPR008917 Eukaryotic transcription factor, DNA-binding IPR011616 bZIP_1. 394.105
IPR000837 Fos transforming protein IPR004827 Basic-leucine zipper (bZIP) transcription factor 353.587
IPR000837 Fos transforming protein IPR011616 bZIP_1. 345.106
IPR000837 Fos transforming protein IPR008917 Eukaryotic transcription factor, DNA-binding 331.206
IPR004827 Basic-leucine zipper (bZIP) transcription factor IPR005643 Jun-like transcription factor 244.11
IPR004827 Basic-leucine zipper (bZIP) transcription factor IPR002112 Transcription factor Jun 244.11
IPR011700 bZIP_2. IPR004827 Basic-leucine zipper (bZIP) transcription factor 223.733
IPR008917 Eukaryotic transcription factor, DNA-binding IPR008917 Eukaryotic transcription factor, DNA-binding 159.35
IPR008917 Eukaryotic transcription factor, DNA-binding IPR005643 Jun-like transcription factor 134.472
IPR008917 Eukaryotic transcription factor, DNA-binding IPR002112 Transcription factor Jun 134.472
IPR011700 bZIP_2. IPR011616 bZIP_1. 133.557
IPR011700 bZIP_2. IPR008917 Eukaryotic transcription factor, DNA-binding 127.677
IPR011700 bZIP_2. IPR002112 Transcription factor Jun 117.176
IPR011700 bZIP_2. IPR005643 Jun-like transcription factor 117.176

The background colour of the table refers to:

  • Blue Domain is only present in FOSL2
  • Yellow Domain is only present in JUNB
  • Green Domain is present in both FOSL2 and JUNB

1.30
Post-translational Modifications

Protein: FOSL2

PTMResidueReference
Phosphorylation 200 PubMed, HPRD
Phosphorylation 230 PubMed, HPRD
Phosphoserine 200 HPRD
Phosphoserine 230 HPRD

Protein: JUNB

PTMResidueReference
Phosphorylation 102 PubMed, HPRD
Phosphorylation 104 PubMed, HPRD
Phosphorylation 259 PubMed, HPRD
Phosphoserine 259 HPRD
Localisation

Protein: FOSL2

LocalisationReference
Nucleus HPRD

Protein: JUNB

LocalisationReference
Nucleus HPRD
Transitive Score

The common interactors between FOSL2 and JUNB that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between FOSL2 andJUNB. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , FOSL2 has 662 interactors and JUNB has 1001 interactors of which there are 636 common interactors.

Common InteractorName of Common InteractorScore for FOSL2-Interactor (?)Score for JUNB-Interactor (?)
JUN JUN: Transcription factor AP-1 856.00 24.40
JUND JUND: Transcription factor jun-D 1.78 84.80
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.275 6.19E3
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.275 0.763
BACH1 BACH1: Transcription regulator protein BACH1 0.251 0.515
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.225 0.275
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.191 0.251
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.191 2.42
ETS2 ETS2: Protein C-ets-2 0.191 0.251
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.188 0.385
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.171 65.60
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.171 0.225
ETS1 ETS1, EWSR2: Protein C-ets-1 0.171 0.225
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.165 0.165
MAPK15 N/A 0.165 0.165
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.165 0.165
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.165 0.165
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.165 0.165
ERF ERF: ETS domain-containing transcription factor ERF 0.152 0.191
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.152 0.225
GTF2F2 N/A 0.152 0.152
TAF1 TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1 0.152 0.098
ELF1 ELF1: ETS-related transcription factor Elf-1 0.152 0.515
CREB1 CREB1: cAMP response element-binding protein 0.148 0.148
RBL1 RBL1: Retinoblastoma-like protein 1 0.148 0.075
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.148 0.148
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.148 0.148
BRD4 N/A 0.148 0.148
VDR VDR, NR1I1: Vitamin D3 receptor 0.139 0.139
NR4A1 CDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor 0.139 0.056
NR4A2 NR4A2, NOT, NURR1, TINUR: Orphan nuclear receptor NR4A2 0.139 0.139
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.136 0.372
CREBBP CREBBP, CBP: CREB-binding protein 0.136 0.275
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.136 0.139
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.136 0.275
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.136 0.275
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.136 0.111
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.136 0.097
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.136 0.275
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.136 0.088
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.127 0.260
IRF3 IRF3: Interferon regulatory factor 3 0.123 0.416
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.123 0.275
H1FX H1FX: Histone H1x 0.123 0.416
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.123 0.191
FOXL2 FOXL2: Forkhead box protein L2 0.123 0.088
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.114 0.233
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.114 0.114
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.114 0.188
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.111 0.172
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.111 0.275
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.111 0.111
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.111 0.171
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.111 0.136
BRPF1 BRPF1, BR140: Peregrin 0.111 0.275
ELK1 ELK1: ETS domain-containing protein Elk-1 0.111 0.088
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.111 82.20
RFX1 RFX1: MHC class II regulatory factor RFX1 0.111 0.097
MAFG MAFG: Transcription factor MafG 0.111 1.78
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.111 0.225
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.111 0.275
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.111 0.225
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.109 0.109
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.109 0.109
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.109 0.136
ERG ERG: Transcriptional regulator ERG 0.109 0.109
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.109 0.098
ETV1 ETV1, ER81: ETS translocation variant 1 0.109 0.110
RB1 RB1: Retinoblastoma-associated protein 0.109 0.127
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.109 0.152
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.099 0.097
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.098 0.109
MYB MYB: Myb proto-oncogene protein 0.098 0.123
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.098 0.152
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.098 0.111
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.098 0.152
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.097 0.171
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.097 0.136
PCAF PCAF: Histone acetyltransferase PCAF 0.097 0.136
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.097 0.275
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.097 0.171
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.097 0.088
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.097 0.111
ID2 ID2: DNA-binding protein inhibitor ID-2 0.0971 0.132
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.096 0.430
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.096 0.260
ROCK1 ROCK1: Rho-associated protein kinase 1 0.096 0.155
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.096 0.077
YAP1 YAP1, YAP65: 65 kDa Yes-associated protein 0.096 0.049
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.096 0.062
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.096 0.210
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.090 0.073
GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 0.088 0.097
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.088 0.088
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.087 0.139
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.086 0.385
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.086 0.139
RELA RELA, NFKB3: Transcription factor p65 0.086 0.139
CXorf9 N/A 0.086 0.233
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.086 0.233
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.086 0.139
SRF SRF: Serum response factor 0.086 0.114
SMAD4 SMAD4, DPC4, MADH4: Mothers against decapentaplegic homolog 4 0.086 0.114
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.086 0.385
SMAD2 SMAD2, MADH2, MADR2: Mothers against decapentaplegic homolog 2 0.086 0.188
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.086 0.188
CUTL1 CUTL1: Homeobox protein cut-like 1 0.083 0.083
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.083 0.083
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.083 0.075
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.083 0.083
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.083 0.083
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.083 0.083
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.083 0.083
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.083 0.083
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.083 0.083
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.083 0.083
C20orf18 N/A 0.083 0.083
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.083 0.075
UHRF1 0.083 0.083
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.083 0.083
NFIL3 NFIL3, E4BP4, IL3BP1: Nuclear factor interleukin-3-regulated protein 0.083 0.074
STAT6 STAT6: Signal transducer and activator of transcription 6 0.0818 0.484
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.080 0.086
AHR AHR: Aryl hydrocarbon receptor precursor 0.080 0.118
SP100 N/A 0.077 0.210
NFATC1 N/A 0.077 0.155
NFIB N/A 0.077 0.056
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.077 0.210
STAT2 STAT2: Signal transducer and activator of transcription 2 0.077 0.127
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.075 0.075
SOX8 SOX8: Transcription factor SOX-8 0.075 0.075
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.075 0.075
DIDO1 N/A 0.075 0.075
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.075 0.075
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.075 0.075
DLX3 DLX3: Homeobox protein DLX-3 0.075 0.148
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.075 0.075
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.075 0.075
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.075 0.075
CCNT2 CCNT2: Cyclin-T2 0.075 0.075
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.075 0.075
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.075 0.075
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.075 0.075
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.075 0.075
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.075 0.075
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.075 0.075
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.075 0.075
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.075 0.075
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.0727 0.064
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.072 0.100
EGR1 EGR1, ZNF225: Early growth response protein 1 0.071 0.114
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.071 0.139
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.071 0.087
STK10 STK10: Uncharacterized protein STK10 0.071 0.233
MTF1 MTF1: Metal regulatory transcription factor 1 0.071 0.233
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.070 0.276
RPS6KB1 N/A 0.069 0.139
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.069 0.188
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.069 0.188
ZBTB16 ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16 0.069 0.056
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 0.069 0.069
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.069 0.139
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.069 0.188
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.086
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.069 0.139
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.069 0.139
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.067 0.185
NBN NBN, NBS, NBS1, P95: Nibrin 0.062 0.155
MEF2A N/A 0.062 0.155
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.062 0.127
STAT4 STAT4: Signal transducer and activator of transcription 4 0.062 0.069
PPARG CREB3L2-PPARgamma 0.062 0.049
XRCC1 XRCC1: DNA-repair protein XRCC1 0.062 0.127
PGR PGR, NR3C3: Progesterone receptor 0.062 0.049
TGIF2 TGIF2: Homeobox protein TGIF2 0.062 0.155
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.060 0.127
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.060 0.077
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.060 0.127
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.060 0.155
SNAI1 SNAI1, SNAH: Zinc finger protein SNAI1 0.060 0.069
ZNF335 ZNF335: Zinc finger protein 335 0.060 0.114
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.057 0.057
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 0.056 0.050
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.056 0.049
HOXB6 HOXB6, HOX2B: Homeobox protein Hox-B6 0.056 0.044
PHF10 N/A 0.056 0.139
CCNH CCNH: Cyclin-H 0.056 0.069
ESRRA ESRRA, ERR1, ESRL1, NR3B1: Steroid hormone receptor ERR1 0.056 0.056
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.056 0.188
CCND1 CCND1, BCL1, PRAD1: G1/S-specific cyclin-D1 0.056 0.049
SMCX JARID1C, DXS1272E, SMCX, XE169: Histone demethylase JARID1C 0.056 0.044
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.056 0.114
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.056 0.139
TP53 TP53, P53: Cellular tumor antigen p53 0.056 0.029
RERE RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei 0.056 0.069
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.056 0.049
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.056 0.056
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.055 0.077
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.055 0.055
BARD1 BARD1: BRCA1-associated RING domain protein 1 0.055 0.056
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.055 0.077
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.055 0.056
PPARA PPARA, NR1C1, PPAR: Peroxisome proliferator-activated receptor alpha 0.055 0.055
SATB2 SATB2, KIAA1034: DNA-binding protein SATB2 0.055 0.049
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.055 0.127
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.055 0.077
ZHX3 ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3 0.055 0.055
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.054 0.069
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.054 0.146
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.054 0.233
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.054 0.086
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.054 0.233
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.054 0.069
MAP2K6 MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki 0.054 0.114
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.052 0.083
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.052 0.083
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.052 0.052
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.052 0.083
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.052 0.083
TFAP4 TFAP4: Transcription factor AP-4 0.052 0.047
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.052 0.075
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.052 0.052
CDC2 CDC2: Cell division control protein 2 homolog 0.052 0.075
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.052 0.052
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.052 0.052
HES6 HES6: Transcription cofactor HES-6 0.052 0.052
ZNF579 ZNF579: Zinc finger protein 579 0.052 0.083
VIM VIM: Vimentin 0.052 0.070
IRS2 IRS2: Insulin receptor substrate 2 0.052 0.087
ELK3 ELK3, NET, SAP2: ETS domain-containing protein Elk-3 0.051 0.051
ATF2 N/A 0.051 0.051
GTF2IRD1 GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12: General transcription 0.051 0.051
PRKCBP1 ZMYND8, KIAA1125, PRKCBP1, RACK7: Protein kinase C-binding protein 1 0.051 0.051
SMARCA2 N/A 0.051 0.051
MAPK11 MAPK11, PRKM11, SAPK2: Mitogen-activated protein kinase 11 0.051 0.051
MAPK7 MAPK7, ERK4, ERK5, PRKM7: Mitogen-activated protein kinase 7 0.051 0.051
CHGB CHGB, SCG1: Secretogranin-1 precursor 0.051 0.045
CHGA CHGA: Chromogranin-A precursor 0.051 0.045
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.0513 0.063
MYBL2 MYBL2, BMYB: Myb-related protein B 0.050 0.049
MAFB MAFB, KRML: Transcription factor MafB 0.050 2.91
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.049 0.077
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.049 0.062
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.049 0.077
STAT3 0.049 0.044
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.049 0.086
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 0.049 0.049
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.049 0.044
PRKCG PRKCG, PKCG: Protein kinase C gamma type 0.049 0.049
MEF2C MEF2C: Myocyte-specific enhancer factor 2C 0.049 0.069
NKX2-5 NKX2-5, CSX, NKX2.5, NKX2E: Homeobox protein Nkx-2.5 0.049 0.049
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.049 0.086
SOX11 SOX11: Transcription factor SOX-11 0.049 0.049
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.049 0.114
SOX4 SOX4: Transcription factor SOX-4 0.049 0.056
CDX2 CDX2, CDX3: Homeobox protein CDX-2 0.049 0.088
SATB1 SATB1: DNA-binding protein SATB1 0.049 0.086
EN2 EN2: Homeobox protein engrailed-2 0.049 0.097
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.049 0.114
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.049 0.086
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.048 0.155
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.048 0.210
ZFX ZFX: Zinc finger X-chromosomal protein 0.048 0.096
ZNF267 ZNF267: Zinc finger protein 267 0.048 0.127
SH3BP3 0.048 0.127
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.047 0.075
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.047 0.047
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.047 0.047
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.047 0.075
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.047 0.047
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.047 0.047
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.047 0.047
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.047 0.075
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.047 0.075
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.047 0.075
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.047 0.075
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.047 3.89
MAX MAX: Protein max 0.047 0.047
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.047 0.075
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.047 0.075
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.047 0.075
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.047 0.075
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.047 0.075
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.047 0.047
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.047 0.075
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.047 0.047
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.047 0.047
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.047 0.075
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.047 0.075
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.047 0.075
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.046 0.827
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.046 0.276
KCTD12 KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12 0.046 0.078
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.046 0.046
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.046 0.067
TRIM24 TRIM24, RNF82, TIF1, TIF1A: Transcription intermediary factor 1-alpha 0.046 0.046
MAPK14 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14 0.046 0.046
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.044 0.050
CDK5R1 CDK5R1, CDK5R, NCK5A: Cyclin-dependent kinase 5 activator 1 precursor 0.044 0.044
CCNB1 Cyclin B1 0.044 0.049
LIG4 LIG4: DNA ligase 4 0.044 0.056
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.043 0.139
YY1 YY1: Transcriptional repressor protein YY1 0.043 0.188
MYO3A MYO3A: Myosin IIIA 0.043 0.044
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.043 0.139
SP3 SP3: Transcription factor Sp3 0.043 0.188
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.043 0.139
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.043 0.114
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.043 0.139
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.043 0.139
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.043 0.139
MYCN MYCN, NMYC: N-myc proto-oncogene protein 0.043 0.035
SP1 SP1, TSFP1: Transcription factor Sp1 0.043 0.086
KLF5 KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5 0.043 0.049
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.0425 0.087
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.0425 0.026
WDR1 N/A 0.0425 0.070
SAT SAT1, SAT: Diamine acetyltransferase 1 0.0425 0.087
EXOC2 N/A 0.041 0.067
IRF1 IRF1: Interferon regulatory factor 1 0.041 0.137
ATF3 ATF3: Cyclic AMP-dependent transcription factor ATF-3 0.041 0.402
ELF4 ELF4, ELFR, MEF: ETS-related transcription factor Elf-4 0.041 0.137
SPI1 SPI1: Transcription factor PU.1 0.041 0.083
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.039 0.0971
STK16 N/A 0.039 0.077
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.039 0.077
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.039 0.039
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.039 0.096
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.039 0.062
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.038 0.129
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.038 0.038
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.038 0.063
DOK1 DOK1: Docking protein 1 0.038 0.078
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.038 0.146
KIAA0690 N/A 0.038 0.063
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.038 0.054
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.038 0.129
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.038 0.276
MAFF MAFF: Transcription factor MafF 0.036 0.218
FLI1 FLI1: Friend leukemia integration 1 transcription factor 0.036 0.123
FOSB FOSB, G0S3: Protein fosB 0.036 0.596
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.036 0.074
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.036 0.044
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.035 0.087
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.035 0.188
MYF5 MYF5: Myogenic factor 5 0.035 0.0308
SMARCA1 SMARCA1, SNF2L, SNF2L1: Probable global transcription activator SNF2L1 0.035 0.031
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.035 0.044
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.035 0.086
HIPK2 HIPK2: Homeodomain-interacting protein kinase 2 0.035 0.049
BAG3 BAG3, BIS: BAG family molecular chaperone regulator 3 0.035 0.028
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.035 0.071
PSKH1 PSKH1: Serine/threonine-protein kinase H1 0.035 0.069
HES1 HES1, HL, HRY: Transcription factor HES-1 0.035 0.0308
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.035 0.044
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.035 0.139
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.035 0.139
ZNF551 N/A 0.035 0.069
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.035 0.188
HAND1 HAND1, EHAND: Heart- and neural crest derivatives-expressed protein 1 0.035 0.028
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.035 0.056
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.035 0.035
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.034 0.049
HMGA2 HMGA2, HMGIC: High mobility group protein HMGI-C 0.034 0.035
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.034 0.096
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.034 0.127
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.034 0.127
PRKAA1 N/A 0.034 0.077
HIVEP1 N/A 0.034 0.077
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.034 0.077
CDKL5 N/A 0.034 0.062
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.034 0.044
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.034 0.055
MECP2 MECP2: Methyl-CpG-binding protein 2 0.034 0.048
PCSK9 PCSK9, NARC1, PSEC0052: Proprotein convertase subtilisin/kexin type 9 precursor 0.034 0.034
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 0.033 0.0818
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.033 0.111
CUL2 CUL2: Cullin-2 0.033 0.076
H1F0 H1F0, H1FV: Histone H1.0 0.033 0.033
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.032 0.087
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.032 0.052
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.032 0.070
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.032 0.070
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.032 0.063
KIAA0853 N/A 0.032 0.052
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.032 0.087
NUP214 N/A 0.032 0.087
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.032 0.032
MARK2 N/A 0.032 0.144
IFI16 N/A 0.032 0.070
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.032 0.087
PLEK PLEK, P47: Pleckstrin 0.032 0.087
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.031 0.044
CIC CIC, KIAA0306: Protein capicua homolog 0.031 0.031
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.031 0.077
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.031 0.050
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.031 0.031
MATR3 MATR3, KIAA0723: Matrin-3 0.031 0.096
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.031 0.062
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.0308 0.054
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.0308 0.056
MTA1 MTA1: Metastasis-associated protein MTA1 0.0308 0.043
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.0308 0.086
MAP2K4 MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k 0.0308 0.056
CDK7 CDK7, MO15: Cell division protein kinase 7 0.0308 0.069
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.0308 0.086
CDK2 CDK2: Cell division protein kinase 2 0.0308 0.056
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.0308 0.049
CDK6 CDK6: Cell division protein kinase 6 0.0308 0.069
BNC1 BNC1, BNC: Zinc finger protein basonuclin-1 0.0308 0.044
IRF5 IRF5: Interferon regulatory factor 5 0.0308 0.083
RCBTB2 RCBTB2, CHC1L, RLG: RCC1 and BTB domain-containing protein 2 0.0308 0.067
RGS7 RGS7: Regulator of G-protein signaling 7 0.031 0.031
KBTBD11 KBTBD11, KIAA0711, KLHDC7C: Kelch repeat and BTB domain-containing protein 11 0.030 0.0338
MBTPS1 MBTPS1, KIAA0091, S1P, SKI1: Membrane-bound transcription factor site-1 protease 0.030 0.030
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.030 0.030
BAT3 BAT3, G3: Large proline-rich protein BAT3 0.030 0.030
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.029 0.026
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.029 0.029
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.029 0.033
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.029 0.063
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.029 0.078
SEC31L1 N/A 0.029 0.038
MYH9 MYH9: Myosin-9 0.029 0.063
FZR1 N/A 0.029 0.029
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.029 0.078
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.029 0.078
DIAPH1 Diaphanous 1 0.029 0.078
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.029 0.129
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.029 0.038
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.029 0.063
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.029 0.038
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.029 0.046
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.029 0.071
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.029 0.129
GSK3B N/A 0.029 0.063
COPA COPA: Coatomer subunit alpha 0.029 0.046
FKBP1A FKBP1A, FKBP1, FKBP12: FK506-binding protein 1A 0.029 0.038
DMXL2 DMXL2, KIAA0856: DmX-like protein 2 0.029 0.046
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.029 0.046
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.029 0.146
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.029 0.063
CORO1C CORO1C, CRNN4: Coronin-1C 0.029 0.046
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
CABLES1 N/A 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
EEF2K EEF2K: Elongation factor 2 kinase 0.028 0.025
PPEF1 N/A 0.028 0.028
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.052
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
FLJ23436 N/A 0.028 0.025
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.028
WDR54 N/A 0.028 0.028
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.028 0.047
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
HDAC8 N/A 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
C13orf8 N/A 0.028 0.028
PHLDB2 N/A 0.028 0.028
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
FBXO4 FBXO4, FBX4: F-box only protein 4 0.028 0.028
CORO6 N/A 0.028 0.028
KIF1B N/A 0.028 0.028
DUSP15 N/A 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.052
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.028 0.028
SNRPB N/A 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.052
HDAC7A N/A 0.028 0.025
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
MAPKAPK5 N/A 0.028 0.052
NES N/A 0.028 0.028
IRF7 N/A 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.028 0.028
ZNF265 N/A 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
NF2 NF2, SCH: Merlin 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
SYTL4 Endocrine transmitter regulatory protein 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
RAB4A N/A 0.028 0.028
BID BID: BH3-interacting domain death agonist 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.052
KCNA2 KCNA2: Potassium voltage-gated channel subfamily A member 2 0.028 0.035
NEDD8 NEDD8: NEDD8 precursor 0.028 0.035
DYRK3 N/A 0.028 0.044
CDK5 CDK5: Cell division protein kinase 5 0.028 0.056
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.028 0.086
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.028 0.049
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.028 0.049
TAL1 TAL1, SCL, TCL5: T-cell acute lymphocytic leukemia protein 1 0.028 0.0308
SALL1 SALL1, SAL1: Sal-like protein 1 0.028 0.050
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.028 0.044
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.028 0.054
CDK4 CDK4: Cell division protein kinase 4 0.028 0.056
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.028 0.050
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.028 0.114
BCL6 BCL6, BCL5, LAZ3, ZBTB27, ZNF51: B-cell lymphoma 6 protein 0.028 0.060
E2F3 E2F3, KIAA0075: Transcription factor E2F3 0.028 0.060
MAFK MAFK: Transcription factor MafK 0.028 0.274
CEBPG CEBPG: CCAAT/enhancer-binding protein gamma 0.028 0.074
CREBL1 N/A 0.028 0.028
ODC1 ODC1: Ornithine decarboxylase 0.0273 0.042
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.027 0.051
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.027 0.029
HILS1 HILS1: Spermatid-specific linker histone H1-like protein 0.027 0.027
ESX1 ESX1L, ESX1R: Extraembryonic, spermatogenesis, homeobox 1-like protein 0.027 0.027
SHOX SHOX, PHOG: Short stature homeobox protein 0.027 0.027
PAX3 PAX3, HUP2: Paired box protein Pax-3 0.027 0.027
OTX2 OTX2: Homeobox protein OTX2 0.027 0.027
BRWD1 N/A 0.027 0.027
HKR3 ZBTB48, HKR3: Zinc finger and BTB domain-containing protein 48 0.027 0.027
CREM hCREM-1: HCREM 1alpha protein 0.027 0.027
SPIC SPIC: Transcription factor Spi-C 0.027 0.027
IRF7 IRF7: Interferon regulatory factor 7 0.027 0.027
HSFY1 HSFY1, HSF2L, HSFY: Heat shock transcription factor, Y-linked 0.027 0.027
GSCL GSCL: Homeobox protein goosecoid-like 0.027 0.027
KBTBD3 DKFZp686D14128, KBTBD3, hCG_40528: Putative uncharacterized protein DKFZp686D141 0.027 0.027
CREM CREM, RP11-324I22.1-005: cAMP responsive element modulator 0.027 0.027
C20orf116 C20orf116: Uncharacterized protein C20orf116 precursor 0.027 0.027
FOXQ1 FOXQ1, HFH1: Forkhead box protein Q1 0.027 0.027
PITX2 PITX2, ARP1, RGS, RIEG, RIEG1: Pituitary homeobox 2 0.027 0.027
SHOX2 SHOX2, OG12X, SHOT: Short stature homeobox protein 2 0.027 0.027
ZYX ZYX: Zyxin 0.027 0.036
MVP MVP, LRP: Major vault protein 0.027 0.074
FLNA FLNA, FLN, FLN1: Filamin-A 0.027 0.0446
RGS2 RGS2, G0S8: Regulator of G-protein signaling 2 0.027 0.157
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.027 0.157
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.0263 0.033
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.026 0.0425
EMD EMD, EDMD, STA: Emerin 0.026 0.026
GAB2 N/A 0.026 0.052
NCOA3 N/A 0.026 0.087
AFF1 N/A 0.026 0.026
GTF3C1 N/A 0.026 0.0425
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.026 0.052
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.026 0.032
RGS14 N/A 0.026 0.070
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.026 0.052
TCF7L2 N/A 0.026 0.026
DAPK2 DAPK2: Death-associated protein kinase 2 0.026 0.039
CHUK N/A 0.026 0.032
PLA2G4A PLA2G4A, CPLA2, PLA2G4: Cytosolic phospholipase A2 0.0253 0.033
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.047
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.025
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.025 0.025
SON 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
NUP98 N/A 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.047
CAMK2A N/A 0.025 0.025
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.025
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
BCOR N/A 0.025 0.025
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.025 0.025
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.025 0.025
KCTD1 0.025 0.025
GEMIN5 GEMIN5: Gem-associated protein 5 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.047
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
GIT2 N/A 0.025 0.025
GRK6 N/A 0.025 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.025 0.025
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
MAP2K3 N/A 0.025 0.025
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.025 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
ELMO1 N/A 0.025 0.025
SEC13L1 N/A 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
RNF20 0.025 0.047
CAMKK1 N/A 0.025 0.025
ATXN2L N/A 0.025 0.025
PRKCB1 N/A 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.025
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.025
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
NIPBL N/A 0.025 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.025
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.025 0.025
TCEA1 N/A 0.025 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.025
HTATIP N/A 0.025 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.047
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
C20orf77 N/A 0.025 0.025
2.15E-3
Total Score 905.00