PIPs: Human Protein-Protein Interaction Prediction

Evidence of Interaction Between PIK3R2 and FYN

The interaction score between PIK3R2 and FYN is 268.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

Feature

Evidence

Score (?)

Gene Expression

N/A

Orthology

Organism	PIK3R2 Orthologue		FYN Orthologue		Experiment
Organism	Accession	Inparalog Score	Accession	Inparalog Score	Experiment
human	IPI00607759	0.536	IPI00029769	0.172
human	IPI00607759	0.536	IPI00016871	0.411
human	IPI00607759	0.536	IPI00013864	0.058
human	IPI00607759	0.536	IPI00298625	0.117
human	IPI00607759	0.536	IPI00479530	0.12
human	IPI00607759	0.536	IPI00396447	0.309
human	IPI00607759	0.536	IPI00013981	0.47
human	IPI00607759	0.536	IPI00328867	0.386
human	IPI00607759	0.536	IPI00306217	0.097
human	IPI00465250	0.585	IPI00029769	0.172
human	IPI00465250	0.585	IPI00016871	0.411
human	IPI00465250	0.585	IPI00013864	0.058
human	IPI00465250	0.585	IPI00298625	0.117
human	IPI00465250	0.585	IPI00479530	0.12
human	IPI00465250	0.585	IPI00396447	0.309
human	IPI00465250	0.585	IPI00013981	0.47
human	IPI00465250	0.585	IPI00328867	0.386
human	IPI00465250	0.585	IPI00306217	0.097
worm	Q9N597	0.536	Q9BKW3	1

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

2.23E-3

Domains

Domains present in PIK3R2 and FYN:

Domains in PIK3R2

Domains in FYN

IPR008936	Rho GTPase activation protein
IPR001452	SH3
IPR000198	RhoGAP domain
IPR000980	SH2 motif
IPR001720	PI3 kinase, P85 regulatory subunit

IPR000719	Protein kinase
IPR001245	Tyrosine protein kinase
IPR008266	Tyrosine protein kinase, active site
IPR011009	Protein kinase-like
IPR001452	SH3
IPR000980	SH2 motif

The Chi square scores for co-occurrence of domains that are present in PIK3R2 and FYN are listed below.

Domain 1		Domain 2		Chi Square
IPR000980	SH2 motif	IPR008266	Tyrosine protein kinase, active site	383.26
IPR000980	SH2 motif	IPR001245	Tyrosine protein kinase	238.73
IPR001452	SH3	IPR008266	Tyrosine protein kinase, active site	164.706
IPR001452	SH3	IPR001245	Tyrosine protein kinase	100.857
IPR000980	SH2 motif	IPR000719	Protein kinase	82.1364
IPR000980	SH2 motif	IPR011009	Protein kinase-like	59.6059
IPR001452	SH3	IPR000980	SH2 motif	59.5667
IPR000980	SH2 motif	IPR000980	SH2 motif	36.445
IPR001720	PI3 kinase, P85 regulatory subunit	IPR008266	Tyrosine protein kinase, active site	28.9958
IPR008936	Rho GTPase activation protein	IPR001452	SH3	27.5985
IPR001452	SH3	IPR000719	Protein kinase	27.1334
IPR000198	RhoGAP domain	IPR001452	SH3	27.0617
IPR008936	Rho GTPase activation protein	IPR000980	SH2 motif	23.5086
IPR000198	RhoGAP domain	IPR000980	SH2 motif	22.7927
IPR001720	PI3 kinase, P85 regulatory subunit	IPR001245	Tyrosine protein kinase	20.8688
IPR001452	SH3	IPR011009	Protein kinase-like	20.4416
IPR001720	PI3 kinase, P85 regulatory subunit	IPR001452	SH3	16.1413
IPR001720	PI3 kinase, P85 regulatory subunit	IPR000980	SH2 motif	14.0342
IPR001720	PI3 kinase, P85 regulatory subunit	IPR011009	Protein kinase-like	9.64929
IPR001720	PI3 kinase, P85 regulatory subunit	IPR000719	Protein kinase	9.22233
IPR008936	Rho GTPase activation protein	IPR008266	Tyrosine protein kinase, active site	9.21621
IPR000198	RhoGAP domain	IPR008266	Tyrosine protein kinase, active site	7.61405
IPR008936	Rho GTPase activation protein	IPR001245	Tyrosine protein kinase	5.16024
IPR000198	RhoGAP domain	IPR001245	Tyrosine protein kinase	3.84971
IPR001452	SH3	IPR001452	SH3	3.15089
IPR008936	Rho GTPase activation protein	IPR000719	Protein kinase	0.485319
IPR000198	RhoGAP domain	IPR000719	Protein kinase	0.472387
IPR008936	Rho GTPase activation protein	IPR011009	Protein kinase-like	0.0380864
IPR000198	RhoGAP domain	IPR011009	Protein kinase-like	0.00301614

The background colour of the table refers to:

Blue Domain is only present in PIK3R2
Yellow Domain is only present in FYN
Green Domain is present in both PIK3R2 and FYN

1.30

Post-translational Modifications

Protein: PIK3R2

PTM	Residue	Reference
Phosphotyrosine	464	HPRD

Protein: FYN

PTM	Residue	Reference
Dephosphorylation	420	PubMed, HPRD
Dephosphorylation	531	PubMed, HPRD
Myristoylation	2	PubMed, HPRD
Palmitoylation	3	PubMed, HPRD
Phosphorylation	28	PubMed, HPRD
Phosphorylation	30	PubMed, HPRD
Phosphorylation	39	PubMed, HPRD
Phosphorylation	420	PubMed, HPRD
Phosphorylation	531	PubMed, HPRD
Phosphotyrosine	530	HPRD
Proteolytic Cleavage	19	PubMed, HPRD

Localisation

Protein: PIK3R2

Localisation	Reference
Plasma membrane	HPRD
Cytoplasm	HPRD

Protein: FYN

Localisation	Reference
Plasma membrane	HPRD
Cytoplasm	HPRD

Transitive Score

The common interactors between PIK3R2 and FYN that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PIK3R2 andFYN. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PIK3R2 has 968 interactors and FYN has 1745 interactors of which there are 902 common interactors.

Common Interactor	Name of Common Interactor	Score for PIK3R2-Interactor (?)	Score for FYN-Interactor (?)
INSR	INSR: Insulin receptor precursor	388.00	0.878
PDGFRB	PDGFRB: Beta-type platelet-derived growth factor receptor precursor	315.00	1.01E3
CSF1R	CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor	250.00	422.00
BMX	N/A	2.42	1.30
INSL3	JAK3: Tyrosine-protein kinase JAK3	1.98	1.30
PTK7	PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor	1.53	0.617
NTRK2	NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor	1.53	0.617
RPL3	RPL3, OK/SW-cl.32: 60S ribosomal protein L3	1.42	0.025
FLT4	VEGFR3 long form	1.37	0.553
EPHB2	EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor	1.33	0.878
ABL2	ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2	1.30	1.30
TESK1	TESK1: Dual specificity testis-specific protein kinase 1	1.20	1.30
ITK	ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK	1.17	1.30
PTK2B	PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta	1.17	1.17
FRK	FRK, PTK5, RAK: Tyrosine-protein kinase FRK	1.07	1.17
PTK2	PTK2, FAK, FAK1: Focal adhesion kinase 1	1.07	563.00
TEC	TEC, PSCTK4: Tyrosine-protein kinase Tec	1.07	563.00
MATK	MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase	1.05	1.30
EPHB4	EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor	1.01	0.878
FGFR1	FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor	0.980	0.980
FGFR3	FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor	0.980	0.980
AXL	AXL, UFO: Tyrosine-protein kinase receptor UFO precursor	0.980	0.980
PTK6	PTK6, BRK: Tyrosine-protein kinase 6	0.975	1.30
SRC	SRC, SRC1: Proto-oncogene tyrosine-protein kinase Src	0.975	1.30
MERTK	MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor	0.902	0.980
EPHA8	EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor	0.878	0.878
RET	RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor	0.878	0.980
EGFR	EGFR, ERBB1: Epidermal growth factor receptor precursor	0.878	0.878
ERBB3	ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor	0.878	0.878
FER	FER, TYK3: Proto-oncogene tyrosine-protein kinase FER	0.874	1.17
LCK	LCK: Proto-oncogene tyrosine-protein kinase LCK	0.872	1.30
EPHA7	EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor	0.808	0.878
EPHB1	EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor	0.808	0.878
FLT1	FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor	0.808	1.01E3
EPHB3	EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor	0.808	0.878
CSK	CSK: Tyrosine-protein kinase CSK	0.781	1.17
JAK1		0.781	1.30
LYN	LYN: Tyrosine-protein kinase Lyn	0.781	1.17
JAK2	JAK2: Tyrosine-protein kinase JAK2	0.781	563.00
ZAP70	ZAP70: Uncharacterized protein ZAP70	0.781	563.00
TXK	TXK, PTK4: Tyrosine-protein kinase TXK	0.781	1.30
SYK	SYK: Tyrosine-protein kinase SYK	0.781	1.30
TYK2	TYK2: Non-receptor tyrosine-protein kinase TYK2	0.781	1.30
ABL1	ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1	0.775	1.30
BTK	BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK	0.770	1.30
MET	MET: Hepatocyte growth factor receptor precursor	0.731	0.980
TEK	TEK, TIE2: Angiopoietin-1 receptor precursor	0.731	0.980
HCK	N/A	0.694	1.17
FGR	FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR	0.694	1.17
YES1	YES1, YES: Proto-oncogene tyrosine-protein kinase Yes	0.694	1.17
MST1R	MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor	0.655	0.878
PDGFRA	PDGFRA: Alpha-type platelet-derived growth factor receptor precursor	0.655	422.00
EPHA4	EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor	0.655	0.878
FGFR4	FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor	0.655	0.878
EPHA1	EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor	0.655	0.878
EPHA3	EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor	0.617	0.617
NTRK1	NTRK1, TRK: High affinity nerve growth factor receptor precursor	0.617	0.617
IGF1R	IGF1R: Insulin-like growth factor 1 receptor precursor	0.586	0.878
KIT	KIT: Mast/stem cell growth factor receptor precursor	0.577	422.00
FLT3	FLT3, STK1: FL cytokine receptor precursor	0.577	0.878
TNK2	TNK2, ACK1: Activated CDC42 kinase 1	0.553	0.553
EPHA2	EPHA2, ECK: Ephrin type-A receptor 2 precursor	0.520	0.878
KDR	KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor	0.520	0.878
ERBB2	ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor	0.520	0.878
EPHA5	EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor	0.483	0.483
ERBB4	ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor	0.448	0.980
ALK	ALK: ALK tyrosine kinase receptor precursor	0.361	0.483
SRMS	SRMS, C20orf148: Tyrosine-protein kinase Srms	0.265	0.265
TNK1	TNK1: Non-receptor tyrosine-protein kinase TNK1	0.237	0.237
LIMK1	LIMK1, LIMK: LIM domain kinase 1	0.225	0.148
MOS	MOS: Proto-oncogene serine/threonine-protein kinase mos	0.225	0.165
TLN2	TLN2: Uncharacterized protein TLN2	0.225	0.148
INSRR	INSRR, IRR: Insulin receptor-related protein precursor	0.225	0.195
MUSK	MUSK: Muscle, skeletal receptor tyrosine protein kinase precursor	0.225	0.217
FGFR2	N/A	0.217	0.217
AMHR2	AMHR2, AMHR: Anti-Muellerian hormone type-2 receptor precursor	0.200	0.217
STYK1	STYK1, NOK: Tyrosine protein-kinase STYK1	0.200	0.217
TYRO3	TYRO3, BYK, DTK, RSE, SKY: Tyrosine-protein kinase receptor TYRO3 precursor	0.200	0.217
RET	urf-ret: Urf-ret protein	0.200	0.217
DDR1	DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE: Epithelial discoidin domain-con	0.195	0.195
MAPK4	MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4	0.191	0.165
SOCS3	SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3	0.191	1.30
CTTN	CTTN, EMS1: Src substrate cortactin	0.191	4.22
GRK1	GRK1, RHOK: Rhodopsin kinase precursor	0.191	0.165
IRS4	IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4	0.191	0.165
PLEKHA5	PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member	0.191	0.165
ROR2	ROR2, NTRKR2: Tyrosine-protein kinase transmembrane receptor ROR2 precursor	0.179	0.195
PLK4	PLK4, SAK, STK18: Serine/threonine-protein kinase PLK4	0.177	0.265
FYN	N/A	0.176	0.265
MATK	DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212	0.176	0.265
EPB41L3	EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3	0.171	0.148
ROCK2	ROCK2, KIAA0619: Rho-associated protein kinase 2	0.171	0.148
SNTA1	SNTA1, SNT1: Alpha-1-syntrophin	0.171	0.148
MAPK12	MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12	0.171	0.148
MAPK8IP1	MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1	0.171	0.148
MYO3A	MYO3A: Myosin IIIA	0.171	0.148
GSK3A	GSK3A: Glycogen synthase kinase-3 alpha	0.171	0.148
PRLR	PRLR: Prolactin receptor precursor	0.166	0.109
TP73	TP73, P73: Tumor protein p73	0.166	0.109
ADAM23	ADAM23, MDC3: ADAM 23 precursor	0.166	0.109
MAPK9	MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9	0.165	0.165
DNM3	DNM3: Uncharacterized protein DNM3	0.165	0.165
LNK	SH2B3, LNK: SH2B adapter protein 3	0.165	1.30
PKN1	PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1	0.165	0.165
CDC2L2	CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2	0.165	0.165
ITSN1	ITSN1, ITSN, SH3D1A: Intersectin-1	0.165	0.165
MAPKAPK5	N/A	0.165	0.165
MINK1	MAP4K6, MINK1, MINK: Misshapen-like kinase 1	0.165	0.165
PSCD1	PSCD1, D17S811E: Cytohesin-1	0.165	0.165
MAPK10	MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10	0.165	0.165
PSCD2	N/A	0.165	0.165
ABI1	ABI1, SSH3BP1: Abl interactor 1	0.165	0.165
SLA2	SLA2, C20orf156, SLAP2: Src-like-adapter 2	0.165	1.30
SGK2	SGK2: Serine/threonine-protein kinase Sgk2	0.165	0.148
DYRK1A	DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin	0.165	0.165
CDC2L1	CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1	0.165	0.165
PTPN6	PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6	0.165	1.30
NF2	NF2, SCH: Merlin	0.165	0.165
MAPK15	N/A	0.165	0.165
AMPH	AMPH, AMPH1: Amphiphysin	0.165	0.165
MAPK8	MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8	0.165	0.165
FRAP1	FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein	0.152	0.165
SPTAN1	N/A	0.152	0.165
SPTA1	SPTA1, SPTA: Spectrin alpha chain, erythrocyte	0.152	0.165
NEK1	NEK1, KIAA1901: Serine/threonine-protein kinase Nek1	0.152	0.165
NPR2	NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor	0.148	0.098
ARHGEF7	N/A	0.148	0.148
CAMK1D	CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D	0.148	0.148
STAT3		0.148	1.17
SPTBN1	SPTBN1, SPTB2: Spectrin beta chain, brain 1	0.148	0.148
ITSN2	ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2	0.148	0.148
RPS6KA4	RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4	0.148	0.148
LATS1	LATS1, WARTS: Serine/threonine-protein kinase LATS1	0.148	0.148
KIAA0031	EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component	0.148	0.025
RASGRP3	RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3	0.148	0.148
GRB2	GRB2, ASH: Growth factor receptor-bound protein 2	0.148	1.17
RASGRP2	RASGRP2: RAS guanyl-releasing protein 2	0.148	0.148
NEK6	NEK6: Serine/threonine-protein kinase Nek6	0.148	0.148
AKT3	AKT3: RAC-gamma serine/threonine-protein kinase	0.148	0.148
CAMK4	CAMK4: Calcium/calmodulin-dependent protein kinase type IV	0.148	0.148
DGKD	DGKD, KIAA0145: Diacylglycerol kinase delta	0.148	0.148
RASA1	RASA1, RASA: Ras GTPase-activating protein 1	0.148	1.30
MKNK2	MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2	0.148	0.148
PRKACA	PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit	0.148	0.148
LATS2	LATS2, KPM: Serine/threonine-protein kinase LATS2	0.148	0.148
EEF2K	EEF2K: Elongation factor 2 kinase	0.148	0.148
BAIAP2	BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2	0.148	0.148
ARL5A	ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A	0.148	0.025
MKNK1	MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1	0.148	0.148
PDPK1	PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1	0.148	0.148
DYRK1B	DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0.148	0.148
EPB41L1	EPB41L1, KIAA0338: Band 4.1-like protein 1	0.148	0.148
RPS6KA2	RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2	0.148	0.148
PHKG1	PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo	0.148	0.148
RAB5B	RAB5B: Ras-related protein Rab-5B	0.148	0.025
CDC2L5	CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5	0.148	0.148
ELMO1	N/A	0.148	0.148
SH3KBP1	SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1	0.148	170.00
DUSP6	DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6	0.148	0.148
BIN1	BIN1, AMPHL: Myc box-dependent-interacting protein 1	0.148	0.148
DUSP16	DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16	0.148	0.148
NEDD9	NEDD9, CASL: Enhancer of filamentation 1	0.148	0.165
CDC2	CDC2: Cell division control protein 2 homolog	0.148	0.148
MAP3K7	MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7	0.148	0.148
ROR1	ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor	0.145	0.195
RYK	RYK, JTK5A: Tyrosine-protein kinase RYK precursor	0.145	0.217
TIE1	TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor	0.143	0.217
PRKD1	PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1	0.136	0.148
RDX	RDX: Radixin	0.136	0.148
PAK6	PAK6, PAK5: Serine/threonine-protein kinase PAK 6	0.136	0.148
CAMK2D	CAMK2D, CAMKD: Calcium/calmodulin-dependent protein kinase type II delta chain	0.136	0.148
PCTK1	PCTK1: Serine/threonine-protein kinase PCTAIRE-1	0.136	0.148
PKMYT1	PKMYT1, MYT1: Membrane-associated tyrosine- and threonine-specific cdc2-inhibito	0.136	0.148
FRS3	FRS3: Fibroblast growth factor receptor substrate 3	0.136	0.148
RRAD	RRAD, RAD: GTP-binding protein RAD	0.136	0.028
DAB1	DAB1: Disabled homolog 1	0.136	71.20
PRKAA2	PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2	0.136	0.148
STK39	STK39, SPAK: STE20/SPS1-related proline-alanine-rich protein kinase	0.136	0.148
CDK5	CDK5: Cell division protein kinase 5	0.136	0.148
PLD1	PLD1: Phospholipase D1	0.136	0.148
PAK7	PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7	0.136	0.148
TTN	N/A	0.136	0.148
LTK	LTK, TYK1: Leukocyte tyrosine kinase receptor precursor	0.128	0.195
DUSP3	DUSP3, VHR: Dual specificity protein phosphatase 3	0.126	0.109
TRPC3	N-terminally extended type 3 canonical transient receptor potential channel	0.126	0.109
KHDRBS1	KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate	0.125	0.187
CDKL5	N/A	0.123	0.165
HUWE1	HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1	0.123	0.165
NEK3	NEK3: Serine/threonine-protein kinase Nek3	0.123	0.165
COBL	N/A	0.123	0.165
GRLF1	N/A	0.123	0.165
RHOB	RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor	0.123	0.025
GAB1	GAB1: GRB2-associated-binding protein 1	0.123	0.165
SQSTM1	SQSTM1: Uncharacterized protein SQSTM1	0.123	0.165
TUBA6	TUBA1C, TUBA6: Tubulin alpha-1C chain	0.113	0.098
CDC7	CDC7, CDC7L1: Cell division cycle 7-related protein kinase	0.111	0.148
APS	SH2B2, APS: SH2B adapter protein 2	0.111	1.17
WEE1	WEE1: Wee1-like protein kinase	0.111	0.165
PLCB1	PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-	0.111	0.148
PIK3CB	PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit	0.111	0.148
MAP2K4	MAP2K4, JNKK1, MKK4, PRKMK4, SERK1: Dual specificity mitogen-activated protein k	0.111	0.148
PRKG1	PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme	0.111	0.148
PRKCE	PRKCE, PKCE: Protein kinase C epsilon type	0.111	71.20
CDK2	CDK2: Cell division protein kinase 2	0.111	0.148
AURKA	AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6	0.111	0.148
CDK4	CDK4: Cell division protein kinase 4	0.111	0.148
DAB2	DAB2, DOC2: Disabled homolog 2	0.111	0.148
HIPK3	HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3	0.111	0.148
PAK4	PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4	0.111	0.148
PRKCA	PRKCA, PKCA, PRKACA: Protein kinase C alpha type	0.111	0.148
STAM2	STAM2: Signal transducing adapter molecule 2	0.111	0.148
MAP2K6	MAP2K6, MEK6, MKK6, PRKMK6: Dual specificity mitogen-activated protein kinase ki	0.111	0.148
CASKIN2	CASKIN2, KIAA1139: Caskin-2	0.111	0.148
BRAF	BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase	0.111	0.148
PRKCZ	PRKCZ, PKC2: Protein kinase C zeta type	0.111	0.148
CHEK1	CHEK1, CHK1: Serine/threonine-protein kinase Chk1	0.111	0.148
DNMBP	DNMBP, KIAA1010: Dynamin-binding protein	0.111	0.148
PRKCQ	PRKCQ, PRKCT: Protein kinase C theta type	0.111	0.148
PSD	TYL: TYL protein	0.111	0.148
CRKRS	CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7	0.111	0.148
CAMK1	CAMK1: Calcium/calmodulin-dependent protein kinase type 1	0.111	0.148
HSPB8	HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8	0.111	0.148
CNKSR2	CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2	0.111	0.148
PBK	PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase	0.111	0.165
RAN	RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran	0.111	0.025
RHOA	RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor	0.110	0.028
RIPK1	RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1	0.110	0.165
SH3BP2	SH3BP2: Uncharacterized protein SH3BP2	0.110	1.30
PRKAA1	N/A	0.110	0.165
VASP	VASP: Vasodilator-stimulated phosphoprotein	0.110	0.165
SLA	SLA, SLAP, SLAP1: SRC-like-adapter	0.110	1.30
PSTPIP1	PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1	0.110	0.165
SIGLEC10	SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor	0.109	0.109
IL4R	IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor	0.109	0.109
TRPV4	TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb	0.109	0.109
LEPR	LEPR, DB, OBR: Leptin receptor precursor	0.109	0.109
ADAM15	ADAM15, MDC15: ADAM 15 precursor	0.109	0.109
CCR2	CCR2, CMKBR2: C-C chemokine receptor type 2	0.109	0.109
PTPRR	PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor	0.109	0.109
CD247	CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor	0.109	0.109
LAT	LAT: Linker for activation of T-cells family member 1	0.109	0.109
IL6ST	IL6ST: Interleukin-6 receptor subunit beta precursor	0.109	0.109
TRPV1	TRPV1: Vanilloid receptor variant TRPV1b	0.109	0.109
NULL	A1BG: Alpha-1B-glycoprotein precursor	0.109	0.109
PTPRE	PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor	0.109	0.098
KIR3DL1	N/A	0.109	0.109
FCGR2B	FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor	0.109	0.109
CD79B	CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p	0.109	0.109
FN1	N/A	0.109	0.109
PTPRC	PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ	0.109	0.098
IRS2	IRS2: Insulin receptor substrate 2	0.109	0.165
CNN3	CNN3: Calponin-3	0.109	0.148
MAP3K8	MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8	0.109	0.165
DAPK2	DAPK2: Death-associated protein kinase 2	0.109	0.165
MPP6	MPP6, VAM1: MAGUK p55 subfamily member 6	0.109	0.165
GAB2	N/A	0.109	0.165
IRS1	IRS1: Insulin receptor substrate 1	0.109	0.165
ICK	ICK, KIAA0936: Serine/threonine-protein kinase ICK	0.109	0.165
MAPK6	MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6	0.109	0.165
SCML2	SCML2: Sex comb on midleg-like protein 2	0.100	0.109
MAG	MAG, GMA: Myelin-associated glycoprotein precursor	0.100	0.109
PIGR	PIGR: Polymeric-immunoglobulin receptor precursor	0.100	0.109
CEACAM1	CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr	0.100	0.109
MPL	MPL, TPOR: Thrombopoietin receptor precursor	0.100	0.109
TUBB3	TUBB3, TUBB4: Tubulin beta-3 chain	0.100	0.109
RAP1A	RAP1A, KREV1: Ras-related protein Rap-1A precursor	0.099	0.025
STK38	STK38, NDR1: Serine/threonine-protein kinase 38	0.099	0.148
PKN2	PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2	0.099	0.148
WASPIP	N/A	0.099	7.88
PSCD4	PSCD4, CYT4: Cytohesin-4	0.099	0.148
ARHGEF6	ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6	0.099	0.148
WAS	WAS, IMD2: Wiskott-Aldrich syndrome protein	0.099	7.88
AKT1	AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase	0.099	0.148
GRK5	GRK5, GPRK5: G protein-coupled receptor kinase 5	0.099	0.148
RPS6KB2	RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2	0.099	0.148
VAV1	VAV1, VAV: Proto-oncogene vav	0.099	1.17
NCK1	NCK1, NCK: Cytoplasmic protein NCK1	0.099	1.17
PTPN12	PTPN12: Tyrosine-protein phosphatase non-receptor type 12	0.099	0.148
ATM	ATM: Serine-protein kinase ATM	0.099	0.148
GRAP2	GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2	0.099	1.17
PRKD2	PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2	0.099	0.148
FNBP1	N/A	0.099	4.22
RPS6KA5	RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5	0.099	0.148
MAPK1	MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1	0.099	0.148
STAT6	STAT6: Signal transducer and activator of transcription 6	0.099	1.17
DYNC1LI1	DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1	0.099	0.025
NEK7	NEK7: Serine/threonine-protein kinase Nek7	0.099	0.148
HCLS1	HCLS1, HS1: Hematopoietic lineage cell-specific protein	0.099	7.88
ELMO2	ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2	0.099	0.148
DOK1	DOK1: Docking protein 1	0.099	0.148
RPS6KB1	N/A	0.099	0.148
PIP5K3	PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase	0.099	0.148
RAPGEF6	RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6	0.099	0.148
DOCK2	DOCK2, KIAA0209: Dedicator of cytokinesis protein 2	0.099	0.148
TAOK3	TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3	0.099	0.148
MAP4K1	MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1	0.098	0.165
STK16	N/A	0.098	0.165
APPL	APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha	0.098	0.165
SRPK2	SRPK2: Serine/threonine-protein kinase SRPK2	0.098	0.165
ROCK1	ROCK1: Rho-associated protein kinase 1	0.098	0.165
BLNK	BLNK, BASH, SLP65: B-cell linker protein	0.098	1.30
PLCG1	PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1	0.098	1.30
OSBPL11	OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11	0.098	0.165
MAPKAPK2	MAPKAPK2: MAP kinase-activated protein kinase 2	0.098	0.165
MAP3K5	MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5	0.098	0.165
MAP3K14	MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14	0.098	0.165
SH2D2A	SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A	0.098	1.30
NCF1	Neutrophil cytosolic factor 1 variant (Fragment)	0.098	0.165
PASK	PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase	0.098	0.165
PTPRF	PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor	0.098	0.098
TRPV6	TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6	0.098	0.098
CHEK2	CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2	0.098	0.098
NEK8	NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8	0.098	0.098
ACVR1B	ACVR1B, ACVRLK4: Activin receptor type-1B precursor	0.098	0.098
STAT1	STAT1: Signal transducer and activator of transcription 1-alpha/beta	0.098	0.878
PHC2	PHC2, EDR2, PH2: Polyhomeotic-like protein 2	0.098	0.098
TRPM7	TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me	0.098	0.098
L1CAM	L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor	0.098	0.098
SSH2	SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2	0.098	0.098
PLK1	PLK1, PLK: Serine/threonine-protein kinase PLK1	0.098	0.098
PTPN2	PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2	0.098	0.098
CSNK2A1	CSNK2A1: CSNK2A1 protein	0.097	0.148
PLD2	PLD2: Phospholipase D2	0.097	0.148
EPB41L2	EPB41L2: Band 4.1-like protein 2	0.097	0.148
RASA3	RASA3: Ras GTPase-activating protein 3	0.097	0.148
CSNK1E	CSNK1E: Casein kinase I isoform epsilon	0.097	0.148
DYRK3	N/A	0.097	0.148
VRK1	VRK1: Serine/threonine-protein kinase VRK1	0.097	0.148
WASL	WASL: Neural Wiskott-Aldrich syndrome protein	0.097	199.00
IQSEC1	IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein	0.097	0.148
MAPK3	MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3	0.097	0.148
SORBS3	SORBS3, SCAM1: Vinexin	0.097	71.20
SGK	SGK, SGK1: Serine/threonine-protein kinase Sgk1	0.097	0.148
NRAS	NRAS, HRAS1: GTPase NRas precursor	0.097	0.025
CRKL	CRKL: Crk-like protein	0.097	1.17
STK11	STK11, LKB1, PJS: Serine/threonine-protein kinase 11	0.097	0.148
CDK7	CDK7, MO15: Cell division protein kinase 7	0.097	0.148
STK3	STK3, MST2: Serine/threonine-protein kinase 3	0.097	0.148
TLN1	TLN1: Uncharacterized protein TLN1	0.097	0.148
CDK6	CDK6: Cell division protein kinase 6	0.097	0.165
MAPKAPK3	MAPKAPK3: MAP kinase-activated protein kinase 3	0.097	0.148
TBK1	TBK1, NAK: Serine/threonine-protein kinase TBK1	0.097	0.165
RPS6KA6	RPS6KA6, RSK4: Ribosomal protein S6 kinase alpha-6	0.094	0.062
MAP3K10	MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10	0.093	0.148
TUBB	TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain	0.090	0.098
MIP	MIP, AQP0: Lens fiber major intrinsic protein	0.090	0.098
CBL	CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL	0.090	0.878
K-ALPHA-1	TUBA1B: Tubulin alpha-1B chain	0.090	0.098
NPR1	NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor	0.090	0.098
TUBB2A	TUBB2A, TUBB2: Tubulin beta-2A chain	0.090	0.098
OXSR1	OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1	0.088	0.148
ANKS1A	ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A	0.088	0.148
TAGLN	TAGLN, SM22, WS3-10: Transgelin	0.088	0.148
OSBP	OSBP, OSBP1: Oxysterol-binding protein 1	0.088	0.148
ILK	ILK, ILK1, ILK2: Integrin-linked protein kinase	0.088	0.148
CD2AP	CD2AP: CD2-associated protein	0.088	0.148
PTEN	PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du	0.088	0.148
EEF2	EEF2, EF2: Elongation factor 2	0.088	0.025
DAPK1	DAPK1, DAPK: Death-associated protein kinase 1	0.088	0.148
RPS6KA1	RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1	0.088	0.148
VIL2	N/A	0.088	0.148
STAM	STAM, STAM1: Signal transducing adapter molecule 1	0.088	0.148
MAP3K11	MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11	0.088	0.165
MAP2K2	MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki	0.088	0.148
PRKCI	PRKCI, DXS1179E: Protein kinase C iota type	0.088	0.148
PIK3CG	PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i	0.088	0.148
RANBP2	RANBP2, NUP358: E3 SUMO-protein ligase RanBP2	0.088	0.148
ARHGAP12	ARHGAP12: Rho GTPase-activating protein 12	0.088	0.148
MAP2K1	MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1	0.088	0.148
ADRBK1	ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1	0.088	0.148
MAPK13	MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13	0.088	0.148
EIF5B	EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B	0.088	0.025
STK24	STK24, MST3, STK3: Serine/threonine-protein kinase 24	0.088	0.148
IRAK1	IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1	0.088	0.148
PLCB3	PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3	0.088	0.148
STK4	STK4, MST1: Serine/threonine-protein kinase 4	0.088	0.148
CXorf9	N/A	0.088	0.148
STAT5A	STAT5A, STAT5: Signal transducer and activator of transcription 5A	0.088	563.00
RAF1	RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase	0.088	0.148
RRAS	RRAS: Ras-related protein R-Ras precursor	0.088	0.025
IKBKB	IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta	0.088	0.165
FABP3	FABP3, FABP11, MDGI: Fatty acid-binding protein, heart	0.086	0.075
SNCA	SNCA, NACP, PARK1: Alpha-synuclein	0.083	0.165
SF1	SF1, ZFM1, ZNF162: Splicing factor 1	0.083	0.083
PRKR	EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki	0.081	0.109
IL9R	IL9R: Interleukin-9 receptor precursor	0.081	0.109
ARHGEF12	ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12	0.081	0.109
CBLC	CBLC, CBL3, RNF57: Signal transduction protein CBL-C	0.081	0.980
CEBPA	CEBPA: CCAAT/enhancer-binding protein alpha	0.081	0.109
GHR	GHR: Growth hormone receptor precursor	0.081	0.109
CD22	CD22, SIGLEC2: B-cell receptor CD22 precursor	0.081	0.109
ICAM5	ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor	0.081	0.109
EPOR	EPOR: Erythropoietin receptor precursor	0.081	0.109
STAT2	STAT2: Signal transducer and activator of transcription 2	0.081	0.980
CENPA	CENPA: Histone H3-like centromeric protein A	0.081	0.109
SNCG	SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein	0.080	0.165
NRBP1	NRBP1, BCON3, NRBP: Nuclear receptor-binding protein	0.078	0.148
SCYL3	SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin	0.078	0.165
PRPF4B	PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol	0.078	0.148
CENTB2	CENTB2, KIAA0041: Centaurin-beta 2	0.078	0.148
STK10	STK10: Uncharacterized protein STK10	0.078	0.148
RAP1B	RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor	0.078	0.025
MSN	MSN: Moesin	0.078	0.148
ROBO1	ROBO1, DUTT1: Roundabout homolog 1 precursor	0.073	0.098
APBA2	APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2	0.073	0.098
TIAM1	TIAM1: T-lymphoma invasion and metastasis-inducing protein 1	0.073	0.109
H2AFX	H2AFX, H2AX: Histone H2A.x	0.073	0.098
PTPRB	PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor	0.073	0.098
ICAM3	ICAM3: Intercellular adhesion molecule 3 precursor	0.0727	0.109
PLEK	PLEK, P47: Pleckstrin	0.0727	0.109
LCP2	LCP2: Lymphocyte cytosolic protein 2	0.0727	0.980
CD4	CD4: T-cell surface glycoprotein CD4 precursor	0.0727	0.109
IFNGR1	IFNGR1: Interferon-gamma receptor alpha chain precursor	0.0727	0.109
F11R	F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor	0.0727	0.109
HLA-A	HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor	0.0727	0.109
CSF2RB	CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor	0.0727	0.109
HLA-DMA	DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP	0.0727	0.109
IL10RA	IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor	0.0727	0.109
JAM2	JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor	0.072	0.109
CXADR	CXADR, CAR: Coxsackievirus and adenovirus receptor precursor	0.072	0.109
SLAMF1	SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor	0.072	0.109
LIFR	LIFR: Leukemia inhibitory factor receptor precursor	0.072	0.109
CD28	CD28: T-cell-specific surface glycoprotein CD28 precursor	0.072	0.109
MS4A1	MS4A1, CD20: B-lymphocyte antigen CD20	0.072	0.109
CD79A	CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain	0.072	0.109
IL12RB2	IL12RB2: Interleukin-12 receptor beta-2 chain precursor	0.072	0.109
MPZL1	MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor	0.072	0.109
CD5	CD5, LEU1: T-cell surface glycoprotein CD5 precursor	0.072	0.109
EPS15L1	EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1	0.071	0.148
NCK2	NCK2: Cytoplasmic protein NCK2	0.070	1.17
FABP5	FABP5: Fatty acid-binding protein, epidermal	0.069	0.075
FXR2	FXR2, FMR1L2: Fragile X mental retardation syndrome-related protein 2	0.069	0.075
IL6R	IL6R: Interleukin-6 receptor alpha chain precursor	0.0688	0.0688
ROBO4	ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor	0.067	0.109
PVR	PVR, PVS: Poliovirus receptor precursor	0.067	0.109
ADCY3	ADCY3, KIAA0511: Adenylate cyclase type 3	0.067	0.049
ITGB2	ITGB2, CD18, MFI7: Integrin beta-2 precursor	0.065	0.098
H3F3A	H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3	0.065	0.098
NACA	NACA, HSD48: Nascent polypeptide-associated complex subunit alpha	0.065	0.098
DUSP1	DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1	0.065	0.098
CD3D	CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor	0.065	0.109
CD3G	CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor	0.065	0.109
IL2RB	IL2RB: Interleukin-2 receptor subunit beta precursor	0.065	0.109
CD47	CD47, MER6: Leukocyte surface antigen CD47 precursor	0.065	0.109
CD3E	CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor	0.065	0.109
F3	F3: Tissue factor precursor	0.065	0.109
IFNAR1	IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor	0.065	0.109
CD33	CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor	0.065	0.109
CCR5	CCR5: CCR5 receptor (Fragment)	0.065	0.109
ETS2	ETS2: Protein C-ets-2	0.065	0.109
HLA-DMB	HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec	0.065	0.109
LILRB1	N/A	0.065	0.109
MCF2	MCF2, DBL: Proto-oncogene DBL	0.064	0.165
TGFBR1	TGFBR1: TGF-beta receptor type-1 precursor	0.064	0.098
TUBA1	TUBA4A, TUBA1: Tubulin alpha-4A chain	0.064	0.098
SOS1	SOS1: Son of sevenless homolog 1	0.064	0.098
HIST1H4A	HIST1H4A, H4/A, HIST1H4B, H4/I, H4/G, HIST1H4D, H4/B, H4/J, HIST1H4F, HIST4H4, H	0.064	0.098
STOML2	STOML2, SLP2, HSPC108: Stomatin-like protein 2	0.062	0.083
PHB2	PHB2, BAP, REA: Prohibitin-2	0.062	0.083
HD	HD, IT15: Huntingtin	0.062	0.083
VSNL1	VSNL1, VISL1: Visinin-like protein 1	0.060	0.165
PDE6G	DKFZp686N1686, PDE6G, hCG_38056: Putative uncharacterized protein DKFZp686N1686	0.059	0.051
HIST3H3	HIST3H3, H3FT: Histone H3.1t	0.058	0.098
PTPN1	PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1	0.058	0.109
NEK9	NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9	0.058	0.098
STAT4	STAT4: Signal transducer and activator of transcription 4	0.058	0.878
STAT5B	STAT5B: Signal transducer and activator of transcription 5B	0.058	422.00
ADAM17	ADAM17, CSVP, TACE: ADAM 17 precursor	0.058	0.098
TGFBR2	TGFBR2: TGF-beta receptor type-2 precursor	0.058	0.098
HIST1H3A	HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD,	0.058	0.098
HLA-B	HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor	0.058	0.109
PSKH1	PSKH1: Serine/threonine-protein kinase H1	0.058	0.148
KAL1	KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor	0.057	0.062
DLG2	DLG2: Disks large homolog 2	0.057	0.062
ATP4A	ATP4A: Potassium-transporting ATPase alpha chain 1	0.057	0.049
BMP2K	BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase	0.056	0.165
GRK7	GRK7, GPRK7: G protein-coupled receptor kinase 7 precursor	0.056	0.056
PRKACB	PRKACB: cAMP-dependent protein kinase, beta-catalytic subunit	0.056	0.165
MAP2K5	N/A	0.056	0.165
CNN2	CNN2: Calponin-2	0.056	0.148
PMP2	PMP2: Myelin P2 protein	0.056	0.075
FABP4	FABP4: Fatty acid-binding protein, adipocyte	0.056	0.075
KIAA0528	KIAA0528: Uncharacterized protein KIAA0528	0.056	0.028
FUBP1	N/A	0.056	0.083
KIAA1967	KIAA1967, DBC1: Protein KIAA1967	0.054	0.148
YWHAG	YWHAG: 14-3-3 protein gamma	0.052	0.028
S100A16	S100A16, AAG13: Protein S100-A16	0.052	0.165
CBLB	CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B	0.052	0.878
MAPK11	MAPK11, PRKM11, SAPK2: Mitogen-activated protein kinase 11	0.051	0.051
GSK3B	GSK3B: Glycogen synthase kinase-3 beta	0.051	0.051
PTPRA	N/A	0.051	0.051
DOK2	DOK2: Docking protein 2	0.051	0.051
C6orf25	G6B, C6orf25: Protein G6b precursor	0.051	0.051
CRK	CRK: Proto-oncogene C-crk	0.051	0.617
PTPNS1	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec	0.051	0.051
DNM1	DNM1, DNM: Dynamin-1	0.051	0.051
C6orf21	LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G	0.051	0.051
SHC1	SHC1, SHC, SHCA: SHC-transforming protein 1	0.051	0.617
KIAA1914	AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2	0.051	0.051
KIRREL	KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor	0.051	0.051
DBNL	DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein	0.051	0.051
GRB10	N/A	0.051	0.617
TJP2	TJP2, X104, ZO2: Tight junction protein ZO-2	0.051	0.051
UBAP2L	N/A	0.051	0.051
MAPK7	MAPK7, ERK4, ERK5, PRKM7: Mitogen-activated protein kinase 7	0.051	0.046
MYLK	MYLK, MLCK: Myosin light chain kinase, smooth muscle	0.051	0.051
BCR	BCR, BCR1, D22S11: Breakpoint cluster region protein	0.051	0.051
CDC42EP1	CDC42EP1, BORG5, CEP1, MSE55: Cdc42 effector protein 1	0.051	0.051
PTPN11	PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11	0.051	0.617
MT3	MT3: Metallothionein-3	0.051	0.165
CENTA1	CENTA1: Centaurin-alpha 1	0.051	0.0688
CD80	CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor	0.051	0.109
THY1	THY1: Thy-1 membrane glycoprotein precursor	0.051	0.109
LILRB5	LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur	0.051	0.109
ITGB3	ITGB3, GP3A: Integrin beta-3 precursor	0.051	0.044
PKN3	PKN3, PKNBETA: Serine/threonine-protein kinase N3	0.050	0.148
PTP4A3	PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3	0.050	0.050
RASD1	RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor	0.050	0.025
WNK4	WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4	0.050	0.148
KIAA1804	MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase	0.050	0.165
GMIP	GMIP: GEM-interacting protein	0.050	0.148
KALRN	DUET, TRAD: Serine/threonine-protein kinase Duet	0.050	0.027
ARHGEF15	ARHGEF15, KIAA0915: Rho guanine nucleotide exchange factor 15	0.050	0.027
HES6	HES6: Transcription cofactor HES-6	0.049	0.049
ACP1	ACP1: Low molecular weight phosphotyrosine protein phosphatase	0.049	0.148
YWHAH	YWHAH, YWHA1: 14-3-3 protein eta	0.048	0.028
SNCB	SNCB: Beta-synuclein	0.048	0.165
S100A7	S100A7, PSOR1: Protein S100-A7	0.048	0.165
GJA5	GJA5: Gap junction alpha-5 protein	0.047	0.051
CTLA4	CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor	0.047	0.051
CDC25C	CDC25C: M-phase inducer phosphatase 3	0.047	0.148
KCNIP3	KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin	0.047	0.165
GSN	GSN: Gelsolin precursor	0.047	0.047
CDC25A	CDC25A: M-phase inducer phosphatase 1	0.047	0.148
SVIL	SVIL: Supervillin	0.047	0.047
EHD4	EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4	0.047	0.148
ACTN4	ACTN4: Alpha-actinin-4	0.047	0.148
NOS1	NOS1: Nitric-oxide synthase, brain	0.046	0.025
MAPK14	MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2: Mitogen-activated protein kinase 14	0.046	0.046
VAV2	VAV2: Uncharacterized protein VAV2	0.046	0.553
PLCG2	PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2	0.046	0.553
SYNGAP1	SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP	0.046	0.046
LRIG2	LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot	0.046	0.046
EPB41	EPB41, E41P: Protein 4.1	0.046	0.046
SYN1	SYN1: Synapsin-1	0.046	0.046
BCAR1	BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1	0.046	22.10
RIN1	RIN1: Ras and Rab interactor 1	0.046	1.17
GRIN2A	GRIN2A, NMDAR2A: Glutamate [NMDA] receptor subunit epsilon-1 precursor	0.046	0.030
NCAM2	NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor	0.046	0.098
CNTN2	CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor	0.046	0.098
BTC	BTC: Probetacellulin precursor [Contains: Betacellulin	0.0453	0.109
AGTR1	AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor	0.0453	0.049
KIF22	KIF22, KID, KNSL4: Kinesin-like protein KIF22	0.0453	0.049
IGFBP3	IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor	0.045	0.0688
IGFBP1	IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor	0.045	0.0688
FER1L3	FER1L3, KIAA1207, MYOF: Myoferlin	0.044	0.025
WWC2	WW and C2 domain containing 2	0.044	0.025
NMT1	NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1	0.044	0.075
HDLBP	HDLBP, HBP, VGL: Vigilin	0.044	0.075
PCBP1	PCBP1: Poly(rC)-binding protein 1	0.044	0.075
FXR1	FXR1: Fragile X mental retardation syndrome-related protein 1	0.044	0.075
PCBP2	PCBP2: Poly(rC)-binding protein 2	0.044	0.075
ADAMTS4	ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor	0.044	0.109
PVRL1	PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor	0.044	0.109
SIGLEC12	SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12	0.044	0.109
PTPRS	PTPRS: Receptor-type tyrosine-protein phosphatase S precursor	0.044	0.109
VCAM1	VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor	0.044	0.109
MDGA1	MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein	0.044	0.109
ATP2A2	ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0.044	0.044
STOM	STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein	0.044	0.044
ADCY6	ADCY6, KIAA0422: Adenylate cyclase type 6	0.044	0.044
ATP1A1	ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor	0.044	0.044
FREQ	FREQ, FLUP, NCS1: Neuronal calcium sensor 1	0.043	0.148
MYL4	MYL4, MLC1, PRO1957: Myosin light polypeptide 4	0.043	0.148
VIL1	VIL1, VIL: Villin-1	0.043	0.052
HPCA	HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin	0.043	0.165
RGS16	RGS16, RGSR: Regulator of G-protein signaling 16	0.0425	0.028
FRS2	FRS2: Fibroblast growth factor receptor substrate 2	0.042	0.046
MAP2K3	MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki	0.0416	0.165
HAVCR1	HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor	0.0407	0.109
PTPRJ	PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor	0.0407	0.109
ICAM1	ICAM1: Intercellular adhesion molecule 1 precursor	0.0407	0.109
FASLG	FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6	0.0407	0.109
NCAM1	NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor	0.0407	0.109
GRIA1	GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor	0.041	21.10
GRIA4	GRIA4, GLUR4: Glutamate receptor 4 precursor	0.041	0.044
GRIK2	GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor	0.041	0.044
HPN	HPN, TMPRSS1: Serine protease hepsin	0.041	0.049
KCNJ12	KCNJ12, IRK2, KCNJN1: ATP-sensitive inward rectifier potassium channel 12	0.041	0.044
KIF3A	KIF3A, KIF3: Kinesin-like protein KIF3A	0.041	0.044
GRIN1	GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor	0.041	0.044
KRTHA8	KRTHA8, HHA8, HKA8: Keratin, type I cuticular Ha8	0.041	0.027
BSG	N/A	0.040	0.098
H2-ALPHA	TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain	0.040	0.098
HIST2H2AC	HIST2H2AC, H2AFQ: Histone H2A type 2-C	0.040	0.098
CNTN4	CNTN4: Contactin-4 precursor	0.040	0.098
CNTN1	CNTN1: Contactin-1 precursor	0.040	0.098
ADAM33	ADAM33, UNQ873/PRO1891: ADAM 33 precursor	0.040	46.90
IQGAP1	IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1	0.040	0.148
PRKDC	PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit	0.039	0.083
TNIK	TNIK, KIAA0551: TRAF2 and NCK-interacting protein kinase	0.038	0.051
SYN2	SYN2: Synapsin-2	0.038	0.051
GJB1	GJB1, CX32: Gap junction beta-1 protein	0.038	0.051
GJA1	GJA1, GJAL: Gap junction alpha-1 protein	0.038	0.051
PITPNM1	PITPNM1: Uncharacterized protein PITPNM1	0.038	0.075
FKBP8	DKFZp686M22160: Putative uncharacterized protein DKFZp686M22160 (Fragment)	0.038	0.028
HIPK2	HIPK2: Homeodomain-interacting protein kinase 2	0.037	0.148
PRKCG	PRKCG, PKCG: Protein kinase C gamma type	0.037	0.148
PTP4A1	PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1	0.037	0.050
LASP1	LASP1, MLN50: LIM and SH3 domain protein 1	0.037	0.165
PIK3CD	PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i	0.037	0.165
KCNJ1	KCNJ1, ROMK1: ATP-sensitive inward rectifier potassium channel 1	0.037	0.04
TNF	TNF, TNFA, TNFSF2: Tumor necrosis factor precursor	0.037	0.049
KIF23	N/A	0.037	0.049
TGFA	TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow	0.037	0.109
LIMK2	LIMK2: LIM domain kinase 2	0.037	0.165
VWF	VWF, F8VWF: von Willebrand factor precursor	0.037	0.062
THBS3	THBS3, TSP3: Thrombospondin-3 precursor	0.037	0.062
MCOLN1	MCOLN1, ML4, MSTP080: Mucolipin-1	0.037	0.062
PTPRZ1	N/A	0.036	0.109
NEO1	NEO1, NGN: Neogenin precursor	0.036	0.098
NCKIPSD	NCKIPSD, AF3P21, SPIN90: SH3 adapter protein SPIN90	0.036	0.027
GGA3	GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3	0.036	0.044
CETN1	CETN1, CEN1, CETN: Centrin-1	0.036	0.109
KLC2	KLC2: Kinesin light chain 2	0.035	0.047
CALM2	CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca	0.035	0.148
CHP	CHP: Calcium-binding protein p22	0.035	0.148
EHD2	EHD2, PAST2: EH domain-containing protein 2	0.035	0.148
S100A11	MLN70, S100A11, S100C: Protein S100-A11	0.035	0.165
GRIN2B	GRIN2B, NMDAR2B: Glutamate [NMDA] receptor subunit epsilon-2 precursor	0.035	0.030
ITGB1BP1	ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1	0.034	0.052
S100A9	S100A9, CAGB, CFAG, MRP14: Protein S100-A9	0.034	0.165
SYN3	SYN3: Synapsin-3	0.034	0.046
CACNG2	CACNG2: Voltage-dependent calcium channel gamma-2 subunit	0.034	0.046
CNN1	CNN1: Calponin-1	0.034	0.046
PECAM1	PECAM1: Platelet endothelial cell adhesion molecule precursor	0.034	0.051
CDC42EP3	CDC42EP3, BORG2, CEP3: Cdc42 effector protein 3	0.034	0.051
TAGLN2	TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein	0.033	0.148
STK38L	STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like	0.033	0.148
STK25	STK25, SOK1, YSK1: Serine/threonine-protein kinase 25	0.033	0.148
HMGA1	HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y	0.0333	0.087
NCF4	NCF4, SH3PXD4: Neutrophil cytosol factor 4	0.033	0.165
TLK1	TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1	0.033	0.165
CLTC	CLTC, CLH17, CLTCL2, KIAA0034: Clathrin heavy chain 1	0.033	0.036
LIG4	LIG4: DNA ligase 4	0.033	0.036
ALCAM	ALCAM, MEMD: CD166 antigen precursor	0.033	0.109
ICOSLG	ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor	0.033	0.109
IL1RL1	IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor	0.033	0.109
ZAK	MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT	0.033	0.109
CD1A	CD1A: T-cell surface glycoprotein CD1a precursor	0.033	0.109
GPA33	GPA33: Cell surface A33 antigen precursor	0.033	0.109
SDC4	SDC4: Syndecan-4 precursor	0.033	0.044
SEMA5A	SEMA5A, SEMAF: Semaphorin-5A precursor	0.033	0.044
SNF1LK2	SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2	0.033	0.165
CCT2	CCT2, 99D8.1, CCTB: T-complex protein 1 subunit beta	0.033	0.148
RAB32	RAB32: Ras-related protein Rab-32	0.033	0.056
IRF3	IRF3: Interferon regulatory factor 3	0.033	0.049
RPS6KA3	RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3	0.033	0.062
ATP2B1	N/A	0.032	0.049
CAMKV	CAMKV: Uncharacterized protein CAMKV	0.032	0.025
NOL3	N/A	0.032	0.028
NEF3	NEFM, NEF3, NFM: Neurofilament medium polypeptide	0.032	0.028
EPN1	N/A	0.032	0.028
ACTN1	ACTN1: Alpha-actinin-1	0.031	0.148
LCP1	LCP1, PLS2: Plastin-2	0.031	0.148
YWHAB	YWHAB: 14-3-3 protein beta/alpha	0.031	0.025
SEC24B	SEC24B: Protein transport protein Sec24B	0.031	0.047
FLII	FLII, FLIL: Protein flightless-1 homolog	0.031	0.047
RYR2	RYR2: Ryanodine receptor 2	0.031	0.0688
CIB1	CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1	0.031	0.165
YWHAQ	YWHAQ: 14-3-3 protein theta	0.031	0.028
ALOX5	ALOX5, LOG5: Arachidonate 5-lipoxygenase	0.031	0.052
JUP	JUP, CTNNG, DP3: Junction plakoglobin	0.0308	0.075
ASB4	ASB4: Ankyrin repeat and SOCS box protein 4	0.0308	0.027
TRIM46	TRIM46, TRIFIC: Tripartite motif-containing protein 46	0.0308	0.027
EPM2A	EPM2A: Laforin	0.0308	0.027
MAP2K7	MAP2K7, JNKK2, MEK7, MKK7, PRKMK7: Dual specificity mitogen-activated protein ki	0.0308	0.027
SPTBN4	SPTBN4, KIAA1642, SPTBN3: Spectrin beta chain, brain 3	0.0308	0.027
CAMK2A	CAMK2A, CAMKA, KIAA0968: Calcium/calmodulin-dependent protein kinase type II alp	0.0308	0.027
AHI1	N/A	0.0308	0.027
ASB1	ASB1: Uncharacterized protein ASB1	0.0308	0.027
PRKG2	PRKG2, PRKGR2: cGMP-dependent protein kinase 2	0.0308	0.027
CLDN3	CLDN3, C7orf1, CPETR2: Claudin-3	0.030	0.051
KCNH2	KCNH2, ERG, ERG1, HERG, HERG1: Potassium voltage-gated channel subfamily H membe	0.030	0.030
HNRPH3	HNRPH3: Heterogeneous nuclear ribonucleoprotein H3	0.030	0.030
EWSR1	EWSR1, EWS: RNA-binding protein EWS	0.030	0.030
PIK3C2A	PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po	0.0296	0.148
SGK3	SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3	0.0296	0.148
DCC	DCC: Netrin receptor DCC precursor	0.030	0.098
SSH1	SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1	0.030	0.098
FURIN	FURIN, FUR, PACE, PCSK3: Furin precursor	0.030	0.098
PTPRG	PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor	0.030	0.098
PTPRM	PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor	0.030	0.098
CD7	CD7: T-cell antigen CD7 precursor	0.029	0.109
SORL1	SORL1: Sortilin-related receptor precursor	0.029	0.098
CRLF3	N/A	0.029	0.109
CD2	CD2, SRBC: T-cell surface antigen CD2 precursor	0.029	0.109
HLA-DPB1	HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor	0.029	0.109
CXCR4	CXCR4: C-X-C chemokine receptor type 4	0.029	0.109
ADRB2	ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor	0.029	0.044
ITGB7	ITGB7: Integrin beta-7 precursor	0.029	0.044
SLC9A1	SLC9A1, APNH1, NHE1: Sodium/hydrogen exchanger 1	0.029	0.049
IL8RB	IL8RB, CXCR2: High affinity interleukin-8 receptor B	0.029	0.049
ITGB4	N/A	0.029	0.109
ADAMDEC1	ADAMDEC1: ADAM DEC1 precursor	0.029	0.109
BCAM	BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor	0.029	0.109
EGF	EGF: Pro-epidermal growth factor precursor	0.029	0.109
SIRPB1	SIRPB1: Signal regulatory protein beta-1 precursor	0.029	0.109
ADAM19	ADAM19, MLTNB, FKSG34: ADAM 19 precursor	0.029	0.109
CD36	CD36, GP3B, GP4: Platelet glycoprotein 4	0.029	0.044
APEX1	APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase	0.029	0.044
HES1	HES1, HL, HRY: Transcription factor HES-1	0.029	0.044
MTAP	MTAP, MSAP: S-methyl-5-thioadenosine phosphorylase	0.029	0.025
PARVA	PARVA, MXRA2: Alpha-parvin	0.029	0.025
ARVCF	ARVCF: Armadillo repeat protein deleted in velo-cardio-facial syndrome	0.029	0.025
CDO1	CDO1: Cysteine dioxygenase type 1	0.029	0.025
ENO2	ENO2: Gamma-enolase	0.029	0.025
MUSK	MUSK: MUSK protein	0.0288	0.0288
TESK2	TESK2: Dual specificity testis-specific protein kinase 2	0.0288	0.0288
NULL	Tyrosine kinase	0.0288	0.0288
AATK	apoptosis-associated tyrosine kinase	0.0288	0.0288
BLK	BLK: Tyrosine-protein kinase BLK	0.0288	0.0288
TTN	TTN: Uncharacterized protein TTN (Fragment)	0.0288	0.0288
BTK	BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros	0.0288	0.0288
NULL	N/A	0.0288	0.0288
NTRK3	N/A	0.0288	0.0288
DDR2	DDR2, NTRKR3, TKT, TYRO10: Discoidin domain-containing receptor 2 precursor	0.0288	0.0288
ROS1	ROS1: Proto-oncogene tyrosine-protein kinase ROS precursor	0.0288	0.0288
FES	Proto-oncogene c-fes variant 4	0.0288	0.0288
NTRK3	NTRK3, TRKC: NT-3 growth factor receptor precursor	0.0288	0.0288
FES	FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps	0.0288	0.0288
NULL	N/A	0.0288	0.0288
FES	Proto-oncogene c-fes variant 3	0.0288	0.0288
CACNB2	N/A	0.028	0.028
WRNIP1	WRNIP1, WHIP: ATPase WRNIP1	0.028	0.025
LNX1	N/A	0.028	0.028
KRT6E	KRT6C, KRT6E: Keratin, type II cytoskeletal 6C	0.028	0.052
CDC42	N/A	0.028	0.028
PPP1R12C	PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C	0.028	0.028
ZNF687	ZNF687, KIAA1441: Zinc finger protein 687	0.028	0.028
UACA	UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats	0.028	0.028
C9orf88	N/A	0.028	0.028
SH2D3A	SH2D3A, NSP1, UNQ175/PRO201: SH2 domain-containing protein 3A	0.028	0.028
PDE5A	PDE5A, PDE5: cGMP-specific 3',5'-cyclic phosphodiesterase	0.028	0.028
CASP9	CASP9, MCH6: Caspase-9 precursor	0.028	0.028
STAP2	Uncharacterized protein ENSP00000317912	0.028	0.028
NCF4	N/A	0.028	0.028
PHLDB2	N/A	0.028	0.028
CASP6	CASP6, MCH2: Caspase-6 precursor	0.028	0.028
CCAR1	CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1	0.028	0.028
SIVA	SIVA1, SIVA: Apoptosis regulatory protein Siva	0.028	0.028
GPRASP2	GPRASP2: G-protein coupled receptor-associated sorting protein 2	0.028	0.028
AXIN1		0.028	0.028
SPAG6	SPAG6, PF16: Sperm-associated antigen 6	0.028	0.028
CASP8	CASP8, MCH5: Caspase-8 precursor	0.028	0.083
FBXO4	FBXO4, FBX4: F-box only protein 4	0.028	0.028
AHSA2	AHSA2, DKFZp564C236, hCG_15158: Putative uncharacterized protein DKFZp564C236	0.028	0.028
TRIM39	TRIM39, RNF23, TFP: Tripartite motif-containing protein 39	0.028	0.028
CASP1	CASP1, IL1BC, IL1BCE: Caspase-1 precursor	0.028	0.028
AKAP12	AKAP12, AKAP250: A-kinase anchor protein 12	0.028	0.083
PKP4	PKP4: Plakophilin-4	0.028	0.028
ABLIM1	ABLIM1, RP11-317F20.1-001: Actin binding LIM protein 1	0.028	0.028
PTPN7	N/A	0.028	0.028
MATK		0.028	0.028
SLC9A3R2	SLC9A3R2: SLC9A3R2 protein (Fragment)	0.028	0.028
RYR1		0.028	0.062
KCNB1	KCNB1: Potassium voltage-gated channel subfamily B member 1	0.028	0.030
HPCAL1	HPCAL1, BDR1: Hippocalcin-like protein 1	0.028	0.148
EPS15	EPS15, AF1P: Epidermal growth factor receptor substrate 15	0.028	0.148
SEC24C	SEC24C, KIAA0079: Protein transport protein Sec24C	0.028	0.047
YWHAZ	YWHAZ: 14-3-3 protein zeta/delta	0.028	0.025
RASAL1	RASAL1, RASAL: RasGAP-activating-like protein 1	0.028	11.50
TAOK1	TAOK1, KIAA1361, MAP3K16: Serine/threonine-protein kinase TAO1	0.0273	0.046
TBC1D1	TBC1D1, KIAA1108: TBC1 domain family member 1	0.0273	0.046
LIG1	LIG1: DNA ligase 1	0.027	0.036
CD44	N/A	0.027	0.049
ABI3	ABI3, NESH: ABI gene family member 3	0.027	0.027
PPP1R9A	PPP1R9A, KIAA1222: Neurabin-1	0.027	0.027
WSB1	WSB1, SWIP1: WD repeat and SOCS box-containing protein 1	0.027	0.027
PDIK1L	PDIK1L, CLIK1L: Serine/threonine-protein kinase PDIK1L	0.027	0.027
NEK11	NEK11: Serine/threonine-protein kinase Nek11	0.027	0.027
ASB10	ASB10: Ankyrin repeat and SOCS box protein 10	0.027	0.027
PLEKHA3	PLEKHA3, FAPP1: Pleckstrin homology domain-containing family A member 3	0.027	0.027
CADPS	CADPS, CAPS, CAPS1, KIAA1121: Calcium-dependent secretion activator 1	0.027	0.027
FAM43A	N/A	0.027	0.027
ASB17	ASB17: Ankyrin repeat and SOCS box protein 17	0.027	0.027
PTPRN2	PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor	0.027	0.027
RIPK5	RIPK5, KIAA0472, HDCMD38P, RIP5, SGK496: Receptor-interacting serine/threonine-p	0.027	0.027
RASGRF2	RASGRF2: Ras protein-specific guanine nucleotide-releasing factor 2 (Fragment)	0.027	0.027
NEBL	N/A	0.027	0.027
CDC2L2	N/A	0.027	0.027
VEPH1	VEPH1, KIAA1692, VEPH: Ventricular zone-expressed PH domain-containing protein h	0.027	0.027
ASB14	ASB14: Ankyrin repeat and SOCS box protein 14	0.027	0.027
OSBPL6	OSBPL6, ORP6: Oxysterol-binding protein-related protein 6	0.027	0.027
PTPN13	N/A	0.027	0.027
BRDG1	STAP1, BRDG1: Signal-transducing adaptor protein 1	0.027	0.265
DOK6	DOK6: Uncharacterized protein DOK6	0.027	0.027
PXK	PXK: PX domain-containing protein kinase-like protein	0.027	0.027
NEK4	NEK4, STK2: Serine/threonine-protein kinase Nek4	0.027	0.027
FANK1	FANK1, HSD13, UNQ6504/PRO21382: Fibronectin type 3 and ankyrin repeat domains pr	0.027	0.027
ASB12	ASB12: Ankyrin repeat and SOCS box protein 12	0.027	0.027
CENTB5	KIAA1716, CENTB5: Centaurin-beta 5	0.027	0.027
ASB6	ASB6: Ankyrin repeat and SOCS box protein 6	0.027	0.027
CAMKK1	CAMKK1, CAMKKA: Calcium/calmodulin-dependent protein kinase kinase 1	0.027	0.027
NOXA1	NOXA1, RP13-927H1.1-001: NADPH oxidase activator 1	0.027	0.027
CASKIN1	N/A	0.027	0.027
RASGRF1	RASGRF1, CDC25: Guanine nucleotide-releasing protein	0.027	0.027
DOK5	DOK5, C20orf180: Docking protein 5	0.027	0.027
ASB3	ASB3: ASB3 protein	0.027	0.027
STK35	STK35, CLIK1, PDIK1: Serine/threonine-protein kinase 35	0.027	0.027
OSBPL9	N/A	0.027	0.027
MPP4	MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4	0.027	0.027
PSD3	N/A	0.027	0.027
UBL7	UBL7, BMSCUBP, SB132: Ubiquitin-like protein 7	0.027	0.027
STAC	STAC: SH3 and cysteine-rich domain-containing protein	0.027	0.027
ALS2CR7	ALS2CR7: Serine/threonine-protein kinase ALS2CR7	0.027	0.027
TRIM9	TRIM9, KIAA0282, RNF91: Tripartite motif-containing protein 9	0.027	0.027
EFS	EFS: Embryonal Fyn-associated substrate	0.027	0.027
PLEKHA4	PLEKHA4, PEPP1: Pleckstrin homology domain-containing family A member 4	0.027	0.027
CISH	CISH, G18: Cytokine-inducible SH2-containing protein	0.027	0.265
MID2	N/A	0.027	0.027
SORBS2	N/A	0.027	0.027
SOCS4	SOCS4, SOCS7: Suppressor of cytokine signaling 4	0.027	0.265
APBB1	APBB1, FE65, RIR: Amyloid beta A4 precursor protein-binding family B member 1	0.027	0.027
ARHGEF1	ARHGEF1: Rho guanine nucleotide exchange factor 1	0.027	0.027
SH2D1B	SH2D1B, EAT2: SH2 domain-containing protein 1B	0.027	0.265
ASB7	ASB7: Ankyrin repeat and SOCS box protein 7	0.027	0.027
SRA1	APBB3, FE65L2: Amyloid beta A4 precursor protein-binding family B member 3	0.027	0.027
SHANK1	SHANK1: SH3 and multiple ankyrin repeat domains protein 1	0.027	0.027
CADPS2	CADPS2, CAPS2, KIAA1591: Calcium-dependent secretion activator 2	0.027	0.027
ANKK1	ANKK1, PKK2, SGK288: Ankyrin repeat and protein kinase domain-containing protein	0.027	0.027
ASB2	ASB2: Ankyrin repeat and SOCS box protein 2	0.027	0.027
TOM1L1	TOM1L1, SRCASM: TOM1-like protein 1	0.0263	0.049
ANXA1	ANXA1, ANX1, LPC1: Annexin A1	0.0263	0.04
ICAM2	ICAM2: Intercellular adhesion molecule 2 precursor	0.026	0.109
CD58	CD58, LFA3: Lymphocyte function-associated antigen 3 precursor	0.026	0.109
TAF6	TAF6, TAF2E, TAFII70: Transcription initiation factor TFIID subunit 6	0.026	0.044
TAF10	TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10	0.026	0.044
ETV6	ETV6, TEL, TEL1: Transcription factor ETV6	0.026	0.098
FES	N/A	0.0258	0.0258
PRPH	PRPH, NEF4, PRPH1: Peripherin	0.026	0.028
BIRC5	BIRC5, API4, IAP4: Baculoviral IAP repeat-containing protein 5	0.026	0.028
PDE4A	N/A	0.026	0.028
ESPL1	N/A	0.026	0.028
LMO7	LMO7, FBX20, FBXO20, KIAA0858: LIM domain only protein 7	0.026	0.028
BIRC4	BIRC4, API3, IAP3, XIAP: Baculoviral IAP repeat-containing protein 4	0.026	0.028
AANAT	AANAT, SNAT: Serotonin N-acetyltransferase	0.026	0.028
BRCA2	BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein	0.026	0.028
NME1	NME1, NDPKA, NM23: Nucleoside diphosphate kinase A	0.026	0.028
RGS4	RGS4: Regulator of G-protein signaling 4	0.026	0.028
NEFH	NEFH, KIAA0845, NFH: Neurofilament heavy polypeptide	0.026	0.028
GFAP	GFAP: Glial fibrillary acidic protein	0.026	0.028
NEDD4L	NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein	0.026	0.028
PAK3	PAK3, OPHN3: Serine/threonine-protein kinase PAK 3	0.026	0.028
PEA15	PEA15: Astrocytic phosphoprotein PEA-15	0.026	0.083
FANCA	FANCA, FAA, FACA, FANCH: Fanconi anemia group A protein	0.026	0.028
CSH2	GH1: Somatotropin precursor	0.025	0.034
EPN2	N/A	0.025	0.025
UBE2A	UBE2A, RAD6A: Ubiquitin-conjugating enzyme E2 A	0.025	0.025
GRK6	N/A	0.025	0.025
UBE2R2	UBE2R2, CDC34B, UBC3B: Ubiquitin-conjugating enzyme E2 R2	0.025	0.025
SMC4L1	SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4	0.025	0.025
SCRIB	N/A	0.025	0.025
PDE8B	PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies	0.025	0.025
CARHSP1	CARHSP1: Calcium-regulated heat stable protein 1	0.025	0.025
FBXL10	FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio	0.025	0.025
CHTF18	RUVBL, CHTF18: Protein CTF18 homolog.	0.025	0.025
NDNL2	NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1	0.025	0.025
GART	GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include	0.025	0.075
ARID1A	ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A	0.025	0.025
BCR	N/A	0.025	0.028
KCNAB2	KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2	0.025	0.075
CPNE1	RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12	0.025	0.025
GIT2	N/A	0.025	0.025
SPAST	SPAST, KIAA1083, SPG4: Spastin	0.025	0.025
LRRC7	LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7	0.025	0.025
PPP1R9B	PPP1R9B, PPP1R6: Neurabin-2	0.025	0.025
RAD51	RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1	0.025	0.025
LTA4H	LTA4H, LTA4: Leukotriene A-4 hydrolase	0.025	0.025
RAC1	N/A	0.025	0.025
PDE4B	PDE4B, DPDE4: cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0.025	0.025
CFL2	CFL2: Cofilin-2	0.025	0.047
DPP8	DPP8, DPRP1, MSTP097, MSTP135, MSTP141: Dipeptidyl peptidase 8	0.025	0.025
NCOA5	NCOA5, KIAA1637: Nuclear receptor coactivator 5	0.025	0.028
DBNL	N/A	0.025	0.025
MAP2K3	N/A	0.025	0.025
BCOR	N/A	0.025	0.025
HSPA8	HSPA8, HSC70, HSP73, HSPA10: Heat shock cognate 71 kDa protein	0.025	0.025
CAMKK1	N/A	0.025	0.025
RAD50	RAD50: DNA repair protein RAD50	0.025	0.025
GOPC	GOPC, CAL, FIG: Golgi-associated PDZ and coiled-coil motif-containing protein	0.025	0.025
PRKCB1	N/A	0.025	0.025
G3BP2	G3BP2, KIAA0660: Ras GTPase-activating protein-binding protein 2	0.025	0.025
TSC2	TSC2, TSC4: Tuberin	0.025	0.083
DCP1B	DCP1B: mRNA-decapping enzyme 1B	0.025	0.025
ADK	ADK: Adenosine kinase	0.025	0.025
SH3PX3	SH3PX3, DKFZp666B159, hCG_1731072: SH3 and PX domain-containing protein 3.	0.025	0.025
RSN	CLIP1, CYLN1, RSN: CAP-Gly domain-containing linker protein 1	0.025	0.025
CAMK2A	N/A	0.025	0.025
MYO18A		0.025	0.028
LMO6	LMO6: LIM domain only protein 6	0.025	0.025
PARD6A	PARD6A, PAR6A: Partitioning defective 6 homolog alpha	0.025	0.075

0.572

Total Score

268.00