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Evidence of Interaction Between SMAD4 and SMAD2

The interaction score between SMAD4 and SMAD2 is 19.20.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between SMAD4 and SMAD2 = 0.46

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 4.62E-3
Orthology
OrganismSMAD4 OrthologueSMAD2 OrthologueExperiment
AccessionInparalog ScoreAccessionInparalog Score
worm P45897 1 Q02330 0.185
fly O61458 1 O96660 0.72

The Inparalog Score is calculated by InParanoid

The experiment type Other refers to techniques other than Y2H, MS, Immunoprecipitation, SurfacePlasmonResonance, XrayDiffraction, Xlinking, CompetitionBinding, Immunofluorescence, GelRetardationAssay, AffinityChromatography, InVitroBinding, InVitro, InVivo, FarWestern, pullDown, AffinityCaptureMS, EpistaticMiniArrayProfile, AffinityCaptureWestern, BiochemicalActivity, CoCrystalStructure, FRET, ReconstitutedComplex, CoLocalization, CoPurification or CoFractionation.

 2.23E-3
Domains Domains present in SMAD4 and SMAD2:
Domains in SMAD4Domains in SMAD2
IPR008984 SMAD/FHA
IPR003619 Dwarfin protein, domain A
IPR001132 Dwarfin protein
IPR013019 MAD_MH1.
IPR003619 Dwarfin protein, domain A
IPR001132 Dwarfin protein
IPR013019 MAD_MH1.

The Chi square scores for co-occurrence of domains that are present in SMAD4 and SMAD2 are listed below.

Domain 1Domain 2Chi Square
IPR008984 SMAD/FHA IPR001132 Dwarfin protein 3.02613
IPR008984 SMAD/FHA IPR013019 MAD_MH1. 3.02613
IPR008984 SMAD/FHA IPR003619 Dwarfin protein, domain A 2.97281
IPR001132 Dwarfin protein IPR001132 Dwarfin protein 1.50263
IPR001132 Dwarfin protein IPR013019 MAD_MH1. 1.50263
IPR013019 MAD_MH1. IPR013019 MAD_MH1. 1.50263
IPR003619 Dwarfin protein, domain A IPR001132 Dwarfin protein 1.46668
IPR003619 Dwarfin protein, domain A IPR013019 MAD_MH1. 1.46668
IPR003619 Dwarfin protein, domain A IPR003619 Dwarfin protein, domain A 1.43121

The background colour of the table refers to:

  • Blue Domain is only present in SMAD4
  • Yellow Domain is only present in SMAD2
  • Green Domain is present in both SMAD4 and SMAD2

 0.083
Post-translational Modifications

Protein: SMAD4

PTMResidueReference
Phosphorylation 277 PubMed, HPRD
Sumoylation 113 PubMed, HPRD
Sumoylation 159 PubMed, HPRD

Protein: SMAD2

PTMResidueReference
Phosphorylation 8 PubMed, HPRD
Phosphorylation 110 PubMed, HPRD
Phosphorylation 220 PubMed, HPRD
Phosphorylation 240 PubMed, HPRD
Phosphorylation 245 PubMed, HPRD
Phosphorylation 250 PubMed, HPRD
Phosphorylation 260 PubMed, HPRD
Phosphorylation 464 PubMed, HPRD
Phosphorylation 465 PubMed, HPRD
Phosphorylation 467 PubMed, HPRD
Phosphoserine 240 PubMed, HPRD
Phosphoserine 465 HPRD
Phosphoserine 467 HPRD
Phosphothreonine 8 PubMed, HPRD
Localisation

Protein: SMAD4

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD

Protein: SMAD2

LocalisationReference
Nucleus HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between SMAD4 and SMAD2 that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between SMAD4 andSMAD2. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , SMAD4 has 867 interactors and SMAD2 has 1164 interactors of which there are 817 common interactors.

Common InteractorName of Common InteractorScore for SMAD4-Interactor (?)Score for SMAD2-Interactor (?)
DHX16 DHX16, DBP2, DDX16, KIAA0577: Putative pre-mRNA-splicing factor ATP-dependent RN 7.05 0.078
HSP90AA1 Hsp89-alpha-delta-N 2.18 0.032
TP53 TP53, P53: Cellular tumor antigen p53 1.58 0.146
FOXJ2 FOXJ2, FHX: Forkhead box protein J2 0.307 0.251
EP300 N/A 0.254 0.078
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.254 0.276
FOXO1A FOXO1A, FKHR: Forkhead box protein O1A 0.225 0.225
HIST1H1B HIST1H1B, H1F5: Histone H1.5 0.216 0.056
RAP1A RAP1A, KREV1: Ras-related protein Rap-1A precursor 0.181 0.503
NRAS NRAS, HRAS1: GTPase NRas precursor 0.181 0.304
DYNC1LI1 DYNC1LI1, DNCLI1: Cytoplasmic dynein 1 light intermediate chain 1 0.171 0.275
RHOA RHOA, ARH12, ARHA, RHO12: Transforming protein RhoA precursor 0.166 0.340
RAB4A N/A 0.165 0.165
FBXO4 FBXO4, FBX4: F-box only protein 4 0.165 0.165
FOXM1 FOXM1, FKHL16, HFH11, MPP2, WIN: Forkhead box protein M1 0.165 0.165
ADPRT PARP1, ADPRT, PPOL: Poly [ADP-ribose] polymerase 1 0.158 0.425
SP100 N/A 0.155 0.260
ZFX ZFX: Zinc finger X-chromosomal protein 0.155 0.155
ELF1 ELF1: ETS-related transcription factor Elf-1 0.155 0.430
TGIF2 TGIF2: Homeobox protein TGIF2 0.155 0.260
NBN NBN, NBS, NBS1, P95: Nibrin 0.155 0.917
ZNF148 ZNF148, ZBP89: Zinc finger protein 148 0.155 0.430
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.152 0.028
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.152 0.191
RAP1B RAP1B, OK/SW-cl.11: Ras-related protein Rap-1b precursor 0.148 0.503
FBXL10 FBXL10, CXXC2, FBL10, JHDM1B, PCCX2: JmjC domain-containing histone demethylatio 0.148 0.148
ARL5A ARL5A, ARFLP5, ARL5: ADP-ribosylation factor-like protein 5A 0.148 0.148
EEA1 EEA1, ZFYVE2: Early endosome antigen 1 0.139 0.114
ZNF24 ZNF24, KOX17, ZNF191, ZSCAN3: Zinc finger protein 24 0.139 0.233
SRF SRF: Serum response factor 0.139 0.233
YY1 YY1: Transcriptional repressor protein YY1 0.139 0.822
NCOR1 NCOR1, KIAA1047: Nuclear receptor corepressor 1 0.139 0.233
HNRPH3 HNRPH3: Heterogeneous nuclear ribonucleoprotein H3 0.137 0.025
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.137 0.025
MLLT7 N/A 0.136 0.111
TCEB3 TCEB3, MSTP059: Transcription elongation factor B polypeptide 3 0.136 0.225
ZNF318 ZNF318, HRIHFB2436: Zinc finger protein 318 0.127 0.430
XRCC6 XRCC6, G22P1: ATP-dependent DNA helicase 2 subunit 1 0.127 0.430
MTF1 MTF1: Metal regulatory transcription factor 1 0.127 90.40
WDR1 N/A 0.127 0.430
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.127 0.210
ZNF76 ZNF76, D6S229E: Zinc finger protein 76 0.127 0.188
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.127 0.144
GNB2L1 Lung cancer oncogene 7 0.127 0.260
HIVEP1 N/A 0.127 0.127
BACH1 BACH1: Transcription regulator protein BACH1 0.127 0.155
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.126 0.078
ZBTB7A ZBTB7A, FBI1, LRF, ZBTB7: Zinc finger and BTB domain-containing protein 7A 0.114 0.069
TCF8 ZEB1, AREB6, TCF8: Zinc finger E-box-binding homeobox 1 0.114 0.139
ETV6 ETV6, TEL, TEL1: Transcription factor ETV6 0.114 0.188
ARPC1B ARC41, ARPC1B: Actin-related protein 2/3 complex subunit 1B 0.114 0.233
ETS1 ETS1, EWSR2: Protein C-ets-1 0.114 0.139
SAFB SAFB, HAP, HET, SAFB1: Scaffold attachment factor B 0.114 0.385
CGI-48 UTP18, WDR50, CDABP0061, CGI-48: U3 small nucleolar RNA-associated protein 18 ho 0.114 0.233
SP3 SP3: Transcription factor Sp3 0.114 0.233
IEF-SSP-9502 PWP1: Periodic tryptophan protein 1 homolog 0.114 0.385
HIRA HIRA, DGCR1, HIR, TUPLE1: Protein HIRA 0.114 0.139
SEC31L1 N/A 0.114 0.233
RPA2 RPA2, REPA2, RPA32, RPA34: Replication protein A 32 kDa subunit 0.114 0.233
ATM ATM: Serine-protein kinase ATM 0.114 0.046
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.114 0.078
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.114 0.385
CXorf9 N/A 0.114 0.385
CREBBP CREBBP, CBP: CREB-binding protein 0.114 90.40
JUNB JUNB: Transcription factor jun-B 0.114 0.188
ATF1 ATF1: Cyclic AMP-dependent transcription factor ATF-1 0.114 0.385
EML4 EML4, C2orf2, EMAPL4: Echinoderm microtubule-associated protein-like 4 0.114 0.114
SUZ12 SUZ12, CHET9, JJAZ1, KIAA0160: Polycomb protein SUZ12 0.114 0.385
ZNF217 ZNF217, ZABC1: Zinc finger protein 217 0.114 0.188
GTF2F1 GTF2F1, RAP74: Transcription initiation factor IIF subunit alpha 0.114 0.233
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.114 0.129
AKAP8 AKAP8, AKAP95: A-kinase anchor protein 8 0.114 0.385
SMAD3 SMAD3, MADH3: Mothers against decapentaplegic homolog 3 0.114 66.70
HIST1H1D HIST1H1D, H1F3: Histone H1.3 0.114 0.139
COPA COPA: Coatomer subunit alpha 0.114 0.233
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.114 0.233
PPP1R8 N/A 0.114 0.385
JUND JUND: Transcription factor jun-D 0.114 0.188
NFE2L2 NFE2L2, NRF2: Nuclear factor erythroid 2-related factor 2 0.114 0.139
EEF2 EEF2, EF2: Elongation factor 2 0.113 0.245
EIF5B EIF5B, IF2, KIAA0741: Eukaryotic translation initiation factor 5B 0.113 0.304
FOXO3A FOXO3A, FKHRL1: Forkhead box protein O3A 0.111 0.136
RRAD RRAD, RAD: GTP-binding protein RAD 0.111 0.097
FOXL2 FOXL2: Forkhead box protein L2 0.111 0.097
GRLF1 N/A 0.109 0.123
NEDD4L NEDD4L, KIAA0439, NEDL3: E3 ubiquitin-protein ligase NEDD4-like protein 0.109 0.109
RASD1 RASD1, AGS1, DEXRAS1: Dexamethasone-induced Ras-related protein 1 precursor 0.098 0.098
RAB5B RAB5B: Ras-related protein Rab-5B 0.098 0.098
KIAA0031 EFTUD2, KIAA0031, SNRP116: 116 kDa U5 small nuclear ribonucleoprotein component 0.098 0.098
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.0971 0.163
POU2F1 POU2F1, OCT1, OTF1: POU domain, class 2, transcription factor 1 0.096 0.127
MATR3 MATR3, KIAA0723: Matrin-3 0.096 0.430
ESR1 ESR1, ESR, NR3A1: Estrogen receptor 0.096 0.049
SAT SAT1, SAT: Diamine acetyltransferase 1 0.096 0.155
ZNF267 ZNF267: Zinc finger protein 267 0.096 0.260
IRF3 IRF3: Interferon regulatory factor 3 0.096 0.260
BATF BATF: Basic leucine zipper transcriptional factor ATF-like 0.096 0.430
ZBTB40 ZBTB40, KIAA0478: Zinc finger and BTB domain-containing protein 40 0.096 0.114
TERF1 TERF1, PIN2, TRBF1, TRF, TRF1: Telomeric repeat-binding factor 1 0.096 0.210
ERG ERG: Transcriptional regulator ERG 0.096 0.077
H1FX H1FX: Histone H1x 0.096 0.155
ERF ERF: ETS domain-containing transcription factor ERF 0.096 0.127
UBTF UBTF, UBF, UBF1: Nucleolar transcription factor 1 0.096 0.260
RAN RAN, ARA24, OK/SW-cl.81: GTP-binding nuclear protein Ran 0.090 0.304
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.087 0.129
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.087 0.146
BTAF1 BTAF1, TAF172: TATA-binding protein-associated factor 172 0.087 0.129
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.087 0.241
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.087 0.078
WDHD1 WDHD1, AND1: WD repeat and HMG-box DNA-binding protein 1 0.086 0.086
KLF13 KLF13, BTEB3, NSLP1: Krueppel-like factor 13 0.086 0.188
SNAI1 SNAI1, SNAH: Zinc finger protein SNAI1 0.086 0.069
HIST1H1E HIST1H1E, H1F4: Histone H1.4 0.086 0.139
HSF2 HSF2, HSTF2: Heat shock factor protein 2 0.086 0.139
HMGB2 HMGB2, HMG2: High mobility group protein B2 0.086 0.188
COPB2 COPB2: Coatomer subunit beta' 0.086 0.188
MEF2D MEF2D: Myocyte-specific enhancer factor 2D 0.086 0.139
CORO1C CORO1C, CRNN4: Coronin-1C 0.086 0.233
GNB1 GNB1: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 0.086 0.233
JUN JUN: Transcription factor AP-1 0.086 0.114
SSRP1 SSRP1, FACT80: FACT complex subunit SSRP1 0.086 0.385
HGS HGS, HRS: Hepatocyte growth factor-regulated tyrosine kinase substrate 0.086 0.188
GNB2 GNB2: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 0.086 0.188
FOS FOS, G0S7: Proto-oncogene protein c-fos 0.086 0.114
AKAP8L AKAP8L, NAKAP95, HRIHFB2018: A-kinase anchor protein 8-like 0.086 0.139
SATB1 SATB1: DNA-binding protein SATB1 0.086 0.114
ZNF224 ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27: Zinc finger protein 224 0.086 0.114
CSTF1 CSTF1: Cleavage stimulation factor 50 kDa subunit 0.086 0.188
FOSL2 FOSL2, FRA2: Fos-related antigen 2 0.086 0.086
ATF6 ATF6: Cyclic AMP-dependent transcription factor ATF-6 alpha 0.086 0.139
MAPK1 MAPK1, ERK2, PRKM1, PRKM2: Mitogen-activated protein kinase 1 0.086 0.233
ZNF335 ZNF335: Zinc finger protein 335 0.086 0.188
ZNF551 N/A 0.086 0.069
PAK1IP1 PAK1IP1, PIP1, WDR84: p21-activated protein kinase-interacting protein 1 0.086 0.188
BTG1 BTG1: Protein BTG1 0.086 0.116
POGZ POGZ, KIAA0461, Nbla00003: Pogo transposable element with ZNF domain 0.083 0.083
SYTL4 Endocrine transmitter regulatory protein 0.083 0.083
PRDM2 PRDM2, RIZ: PR domain zinc finger protein 2 0.083 0.075
KIAA1443 HOMEZ, KIAA1443: Homeobox and leucine zipper protein Homez 0.083 0.083
ZFP91 ZFP91, FKSG11: Zinc finger protein 91 homolog 0.083 0.083
MAPK9 MAPK9, JNK2, PRKM9: Mitogen-activated protein kinase 9 0.083 0.083
ELF2 ELF2, NERF: ETS-related transcription factor Elf-2 0.083 0.083
HTATIP HTATIP, TIP60: Histone acetyltransferase HTATIP 0.083 0.083
ZNF579 ZNF579: Zinc finger protein 579 0.083 0.083
TLE3 TLE3, KIAA1547: Transducin-like enhancer protein 3 0.083 0.083
NIPA1 NIPA1: Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 0.083 0.083
MAPK15 N/A 0.083 0.083
ZHX1 ZHX1: Zinc fingers and homeoboxes protein 1 0.083 0.083
CCAR1 CCAR1, CARP1, DIS: Cell division cycle and apoptosis regulator protein 1 0.083 0.083
ZNF644 ZNF644, KIAA1221, ZEP2: Zinc finger protein 644 0.083 0.083
CUTL1 CUTL1: Homeobox protein cut-like 1 0.083 0.083
WDR54 N/A 0.083 0.083
ZNF295 ZNF295, KIAA1227, ZBTB21: Zinc finger protein 295 0.083 0.083
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.0818 0.227
VAV1 VAV1, VAV: Proto-oncogene vav 0.0818 0.137
RB1 RB1: Retinoblastoma-associated protein 0.080 0.132
MEF2A N/A 0.077 0.155
ZBTB33 KAISO, ZBTB33, ZNF348: Transcriptional regulator Kaiso 0.077 0.077
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.077 0.087
ETS2 ETS2: Protein C-ets-2 0.077 0.096
MKI67 MKI67: Antigen KI-67 0.077 0.127
SH3BP3 0.077 0.127
TERF2 TERF2, TRBF2, TRF2: Telomeric repeat-binding factor 2 0.077 0.155
MYB MYB: Myb proto-oncogene protein 0.077 0.077
GTF2F2 N/A 0.077 0.127
SNAPC4 SNAPC4, SNAP190: snRNA-activating protein complex subunit 4 0.077 0.155
NUP214 N/A 0.077 0.096
REST REST, NRSF, XBR: RE1-silencing transcription factor 0.077 0.096
SMAD7 SMAD7, MADH7, MADH8: Mothers against decapentaplegic homolog 7 0.077 0.077
RAB8A RAB8A: RAB8A protein 0.076 0.257
ISL2 ISL2: Insulin gene enhancer protein ISL-2 0.075 0.075
ZNF174 ZNF174, ZSCAN8: Zinc finger protein 174 0.075 0.075
CHEK2 CHEK2, CHK2, RAD53: Serine/threonine-protein kinase Chk2 0.075 0.075
SMU1 SMU1: Smu-1 suppressor of mec-8 and unc-52 protein homolog 0.075 0.075
FARSLA FARSA, FARS, FARSL, FARSLA: Phenylalanyl-tRNA synthetase alpha chain 0.075 0.075
GEMIN5 GEMIN5: Gem-associated protein 5 0.075 0.075
RFFL RFFL, RNF189, RNF34L: E3 ubiquitin-protein ligase rififylin 0.075 0.075
WWTR1 WWTR1, TAZ: WW domain-containing transcription regulator protein 1 0.075 0.075
ZFPM1 ZFPM1, FOG1: Zinc finger protein ZFPM1 0.075 0.075
BUB3 BUB3: Mitotic checkpoint protein BUB3 0.075 0.075
DLX3 DLX3: Homeobox protein DLX-3 0.075 0.075
CREB1 CREB1: cAMP response element-binding protein 0.075 0.075
TRERF1 TRERF1, BCAR2, RAPA, TREP132: Transcriptional-regulating factor 1 0.075 0.075
OSR1 OSR1, ODD: Protein odd-skipped-related 1 0.075 0.075
SMAD1 SMAD1, BSP1, MADH1, MADR1: Mothers against decapentaplegic homolog 1 0.075 35.90
SOX8 SOX8: Transcription factor SOX-8 0.075 0.075
HOXA10 HOXA10, HOX1H: Homeobox protein Hox-A10 0.075 0.075
raptor RAPTOR, KIAA1303: Regulatory-associated protein of mTOR 0.075 0.075
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.075 0.075
RBM10 RBM10, CTD-2522E6.5-001, hCG_1811529: RNA binding motif protein 10 0.075 0.075
RAC2 RAC2: Ras-related C3 botulinum toxin substrate 2 precursor 0.0735 0.435
RRAS RRAS: Ras-related protein R-Ras precursor 0.073 0.073
RHOB RHOB, ARH6, ARHB: Rho-related GTP-binding protein RhoB precursor 0.072 0.072
BRD3 BRD3, KIAA0043, RING3L: Bromodomain-containing protein 3 0.071 0.087
RBL2 RBL2, RB2: Retinoblastoma-like protein 2 0.071 0.118
BAZ2A BAZ2A, KIAA0314, TIP5: Bromodomain adjacent to zinc finger domain protein 2A 0.071 0.146
BRD2 BRD2, KIAA9001, RING3: Bromodomain-containing protein 2 0.071 0.241
SOS1 SOS1: Son of sevenless homolog 1 0.071 0.118
PRKAR1A PRKAR1A, PKR1, PRKAR1, TSE1: cAMP-dependent protein kinase type I-alpha regulato 0.071 0.094
EDD1 EDD1, EDD, HYD, KIAA0896: E3 ubiquitin-protein ligase EDD1 0.071 0.155
TGFBR2 TGFBR2: TGF-beta receptor type-2 precursor 0.071 0.071
EIF3S5 N/A 0.070 0.143
CEBPB CEBPB, TCF5, PP9092: CCAAT/enhancer-binding protein beta 0.069 0.114
RERE RERE, ARG, ARP, ATN1L, KIAA0458: Arginine-glutamic acid dipeptide repeats protei 0.069 0.086
NR5A1 NR5A1, AD4BP, FTZF1, SF1: Steroidogenic factor 1 0.069 0.086
SOX4 SOX4: Transcription factor SOX-4 0.069 0.086
HIST1H1A HIST1H1A, H1F1: Histone H1.1 0.069 0.056
ACIN1 ACIN1, ACINUS, KIAA0670: Apoptotic chromatin condensation inducer in the nucleus 0.069 0.188
SP1 SP1, TSFP1: Transcription factor Sp1 0.069 0.069
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.069 0.056
EIF3S2 EIF3S2, TRIP1: Eukaryotic translation initiation factor 3 subunit 2 0.069 0.233
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.069 0.029
PCAF PCAF: Histone acetyltransferase PCAF 0.069 0.086
BRPF1 BRPF1, BR140: Peregrin 0.069 0.114
GTPBP4 GTPBP4, CRFG, NOG1: Nucleolar GTP-binding protein 1 0.067 0.228
CDC42 CDC42: Cell division control protein 42 homolog precursor 0.067 0.228
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.067 0.137
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.067 0.111
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.067 0.111
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.063 0.063
SIRT1 SIRT1, SIR2L1: NAD-dependent deacetylase sirtuin-1 0.063 0.063
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.062 0.062
TERF2IP TERF2IP, RAP1, PP8000: Telomeric repeat-binding factor 2-interacting protein 1 0.062 0.127
YAP1 YAP1, YAP65: 65 kDa Yes-associated protein 0.062 0.049
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.062 0.062
DDIT3 DDIT3, CHOP, GADD153: DNA damage-inducible transcript 3 0.062 0.062
AANAT AANAT, SNAT: Serotonin N-acetyltransferase 0.062 0.062
ETV1 ETV1, ER81: ETS translocation variant 1 0.062 0.056
E2F1 E2F1, RBBP3: Transcription factor E2F1 0.062 0.096
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.062 0.069
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.062 29.60
FLNA FLNA, FLN, FLN1: Filamin-A 0.061 0.101
TRIP12 TRIP12, KIAA0045: Probable E3 ubiquitin-protein ligase TRIP12 0.059 0.160
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.057 27.30
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.057 0.124
CDC20 CDC20: Cell division cycle protein 20 homolog 0.056 0.114
ORC1L ORC1L, ORC1, PARC1: Origin recognition complex subunit 1 0.056 0.086
KLF5 KLF5, BTEB2, CKLF, IKLF: Krueppel-like factor 5 0.056 0.044
MEF2C MEF2C: Myocyte-specific enhancer factor 2C 0.056 0.069
MYST4 MYST4, KIAA0383, MORF, MOZ2: Histone acetyltransferase MYST4 0.056 0.056
SLC4A1AP SLC4A1AP: Uncharacterized protein SLC4A1AP 0.056 0.086
MAFG MAFG: Transcription factor MafG 0.056 0.114
EGR1 EGR1, ZNF225: Early growth response protein 1 0.056 0.056
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.056 33.10
SOX11 SOX11: Transcription factor SOX-11 0.056 0.049
LEF1 LEF1: Lymphoid enhancer-binding factor 1 0.056 0.056
CDC6 CDC6, CDC18L: Cell division control protein 6 homolog 0.056 0.086
BRCA1 BRCA1, RNF53: Breast cancer type 1 susceptibility protein 0.056 0.114
CEBPE CEBPE: CCAAT/enhancer-binding protein epsilon 0.056 0.069
HSF1 HSF1, HSTF1: Heat shock factor protein 1 0.056 0.086
VDR VDR, NR1I1: Vitamin D3 receptor 0.056 0.086
CHAF1B CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7: Chromatin assembly factor 1 subunit B 0.056 0.139
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.056 0.029
BAG3 BAG3, BIS: BAG family molecular chaperone regulator 3 0.056 0.044
BNC1 BNC1, BNC: Zinc finger protein basonuclin-1 0.056 0.044
MYBL2 MYBL2, BMYB: Myb-related protein B 0.056 0.114
GCN5L2 GCN5L2, GCN5, HGCN5: General control of amino acid synthesis protein 5-like 2 0.056 41.40
ZFYVE16 ZFYVE16, KIAA0305: Zinc finger FYVE domain-containing protein 16 0.056 0.086
KLF1 KLF1, EKLF: Krueppel-like factor 1 0.056 0.056
ZBTB16 ZBTB16, PLZF, ZNF145: Zinc finger and BTB domain-containing protein 16 0.055 0.049
NFIB N/A 0.055 0.031
ZHX3 ZHX3, KIAA0395, TIX1: Zinc fingers and homeoboxes protein 3 0.055 0.055
TP73 TP73, P73: Tumor protein p73 0.055 0.062
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.055 0.026
LCP1 LCP1, PLS2: Plastin-2 0.054 0.394
XPO1 XPO1, CRM1: Exportin-1 0.054 0.066
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.054 0.394
KIAA0690 N/A 0.054 0.029
SYMPK SYMPK, SPK: Symplekin 0.054 0.046
MLL MLL, ALL1, HRX, HTRX, TRX1: Zinc finger protein HRX 0.054 0.071
STAMBP STAMBP, AMSH: STAM-binding protein 0.053 0.237
RAB7 RAB7A, RAB7: Ras-related protein Rab-7a 0.053 0.143
C20orf18 N/A 0.052 0.052
UHRF1 0.052 0.052
KIAA0853 N/A 0.052 0.087
NCOA3 N/A 0.052 0.144
USP24 USP24, KIAA1057: Ubiquitin carboxyl-terminal hydrolase 24 0.052 0.087
NR3C1 NR3C1, GRL: Glucocorticoid receptor 0.052 0.144
RBM3 RBM3, RNPL: Putative RNA-binding protein 3 0.052 0.144
STRN3 STRN3, GS2NA, SG2NA: Striatin-3 0.052 0.0425
NFATC1 N/A 0.052 0.052
ROCK1 ROCK1: Rho-associated protein kinase 1 0.052 0.087
PTMA N/A 0.052 0.144
RFXDC2 RFXDC2: Regulatory factor X domain-containing protein 2. 0.052 0.070
SFRS15 SFRS15, KIAA1172: Splicing factor, arginine/serine-rich 15 0.052 0.0425
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.052 0.052
AFF1 N/A 0.052 0.070
PHF3 PHF3, KIAA0244: PHD finger protein 3 0.052 0.144
CHUK N/A 0.052 0.087
PHF8 PHF8, KIAA1111, ZNF422: PHD finger protein 8 0.052 0.032
IFI16 N/A 0.052 0.307
FBXO38 FBXO38, SP329: F-box only protein 38 0.051 0.051
NEDD4L N/A 0.051 0.051
RHOG RHOG, ARHG: Rho-related GTP-binding protein RhoG precursor 0.051 0.111
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.051 0.067
DPF2 DPF2, REQ, UBID4: Zinc finger protein ubi-d4 0.051 0.137
UBE2E3 UBE2E3, UBCE4, UBCH9: Ubiquitin-conjugating enzyme E2 E3 0.051 15.50
RAB1B RAB1B: Ras-related protein Rab-1B 0.050 0.050
FBXW2 FBXW2, FBW2, FWD2: F-box/WD repeat-containing protein 2 0.050 0.137
MAPK10 MAPK10, JNK3, JNK3A, PRKM10: Mitogen-activated protein kinase 10 0.049 0.049
MAP2K5 N/A 0.049 0.049
MAPK8 MAPK8, JNK1, PRKM8: Mitogen-activated protein kinase 8 0.049 0.049
AXIN1 0.049 0.049
CNN2 CNN2: Calponin-2 0.049 0.049
CDX2 CDX2, CDX3: Homeobox protein CDX-2 0.049 0.049
SATB2 SATB2, KIAA1034: DNA-binding protein SATB2 0.049 0.049
EN2 EN2: Homeobox protein engrailed-2 0.049 0.044
NKX2-5 NKX2-5, CSX, NKX2.5, NKX2E: Homeobox protein Nkx-2.5 0.049 0.044
RFX1 RFX1: MHC class II regulatory factor RFX1 0.049 0.049
DYNC1I2 N/A 0.049 0.086
BCDO2 PTS: 6-pyruvoyl tetrahydrobiopterin synthase 0.049 0.086
ELK1 ELK1: ETS domain-containing protein Elk-1 0.049 0.049
SALL1 SALL1, SAL1: Sal-like protein 1 0.049 0.049
TRIM28 TRIM28, KAP1, RNF96, TIF1B: Transcription intermediary factor 1-beta 0.048 0.132
BAZ1B BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF: Bromodomain adjacent to zinc finger domain 0.048 0.132
TAF1 TAF1, BA2R, CCG1, CCGS, TAF2A: Transcription initiation factor TFIID subunit 1 0.048 0.034
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.048 0.026
NIPBL N/A 0.047 0.025
BRD4 N/A 0.047 0.047
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.047 0.047
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.047 0.047
RBL1 RBL1: Retinoblastoma-like protein 1 0.047 0.047
GMCL1L GMCL1L, GCL: Germ cell-less protein-like 1-like 0.046 18.30
TDG TDG: G/T mismatch-specific thymine DNA glycosylase 0.046 0.129
DDX3X DDX3X, DBX, DDX3: ATP-dependent RNA helicase DDX3X 0.046 0.129
RREB1 RREB1, FINB: RAS-responsive element-binding protein 1 0.046 0.046
DDX5 DDX5, G17P1, HELR, HLR1: Probable ATP-dependent RNA helicase DDX5 0.046 0.129
DICER1 DICER1, DICER, HERNA, KIAA0928: Endoribonuclease Dicer 0.046 0.129
JARID1A JARID1A, RBBP2, RBP2: Histone demethylase JARID1A 0.046 0.129
ZCCHC8 ZCCHC8: Zinc finger CCHC domain-containing protein 8 0.046 0.129
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.046 0.063
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.046 0.078
RBM8A RBM8A, RBM8, HSPC114, MDS014: RNA-binding protein 8A 0.046 0.129
SFRS10 SFRS10, TRA2B: Splicing factor, arginine/serine-rich 10 0.046 0.129
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.046 0.063
PPP1R12A PPP1R12A, MBS, MYPT1: Protein phosphatase 1 regulatory subunit 12A 0.046 0.129
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.046 0.046
STAG2 STAG2, SA2: Cohesin subunit SA-2 0.046 0.129
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.046 0.063
ARID3A ARID3A, DRIL1, DRIL3, DRX, E2FBP1: AT-rich interactive domain-containing protein 0.046 0.046
PRPF4B PRPF4B, KIAA0536, PRP4, PRP4H, PRP4K: Serine/threonine-protein kinase PRP4 homol 0.046 0.129
UTX UTX: Ubiquitously transcribed X chromosome tetratricopeptide repeat protein 0.046 0.063
USP34 USP34, KIAA0570, KIAA0729: Ubiquitin carboxyl-terminal hydrolase 34 0.046 0.078
PIK4CB PIK4CB, RP11-126K1.4-003, hCG_1811976: Phosphatidylinositol 4-kinase, catalytic, 0.046 0.129
FNBP1 N/A 0.046 0.276
KIAA1012 KIAA1012: Protein TRS85 homolog 0.046 0.129
SFRS5 SFRS5, HRS, SRP40: Splicing factor, arginine/serine-rich 5 0.046 0.078
RPS6KB1 N/A 0.046 0.129
PAPOLA PAPOLA, PAP: Poly(A) polymerase alpha 0.046 0.276
HDAC1 HDAC1, RPD3L1: Histone deacetylase 1 0.046 0.276
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.046 0.078
HD HD, IT15: Huntingtin 0.046 0.0446
RAB37 RAB37: Ras-related protein Rab-37 0.046 0.046
PSMD14 PSMD14, POH1: 26S proteasome non-ATPase regulatory subunit 14 0.046 0.046
NOTCH2 NOTCH2: Neurogenic locus notch homolog protein 2 precursor 0.046 0.056
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.046 0.156
RAB5A RAB5A, RAB5: Ras-related protein Rab-5A 0.046 0.100
RAB11A RAB11A, RAB11: Ras-related protein Rab-11A 0.046 0.123
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.0453 0.057
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.0453 0.051
PIAS1 PIAS1, DDXBP1: E3 SUMO-protein ligase PIAS1 0.044 18.10
FOXP1 FOXP1, HSPC215: Forkhead box protein P1 0.044 0.028
ARF6 ARF6: ADP-ribosylation factor 6 0.044 0.123
FBXO28 FBXO28, KIAA0483: F-box only protein 28 0.044 0.123
NR1D1 NR1D1, EAR1, HREV, THRAL: Orphan nuclear receptor NR1D1 0.044 0.044
HOXB6 HOXB6, HOX2B: Homeobox protein Hox-B6 0.044 0.044
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.044 0.044
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.044
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.043 0.071
JMJD1A JMJD1A, JHDM2A, JMJD1, KIAA0742: JmjC domain-containing histone demethylation pr 0.0425 0.087
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.0425 0.087
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.0425 0.144
HNRPA0 HNRPA0: Heterogeneous nuclear ribonucleoprotein A0 0.0425 0.087
PRKR EIF2AK2, PKR, PRKR: Interferon-induced, double-stranded RNA-activated protein ki 0.0425 0.052
UBAP2L UBAP2L, KIAA0144, NICE4: Ubiquitin-associated protein 2-like 0.0425 0.144
DDX21 DDX21: Nucleolar RNA helicase 2 0.0425 0.144
VCPIP1 VCPIP1, KIAA1850, VCIP135: Deubiquitinating protein VCIP135 0.0425 0.052
MAP3K5 MAP3K5, ASK1, MAPKKK5, MEKK5: Mitogen-activated protein kinase kinase kinase 5 0.0425 0.087
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.0425 0.070
STAT2 STAT2: Signal transducer and activator of transcription 2 0.0425 0.0425
DEF6 DEF6, IBP: Differentially expressed in FDCP 6 0.0425 0.070
RBMX RBMX, HNRPG, RBMXP1: Heterogeneous nuclear ribonucleoprotein G 0.0425 0.144
RGS14 N/A 0.0425 0.070
DDX46 DDX46, KIAA0801: Probable ATP-dependent RNA helicase DDX46 0.0425 0.144
MARK2 N/A 0.0425 0.070
RBM14 RBM14, SIP: RNA-binding protein 14 0.0425 0.144
SH2BP1 CTR9, KIAA0155, SH2BP1: RNA polymerase-associated protein CTR9 homolog 0.0425 0.144
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.0425 0.087
TOP2B N/A 0.0425 0.087
GAB1 GAB1: GRB2-associated-binding protein 1 0.0425 0.026
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.0425 0.087
FNBP4 FNBP4, FBP30, KIAA1014: Formin-binding protein 4 0.0425 0.070
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.0425 0.046
IKBKG IKBKG, FIP3, NEMO: NF-kappa-B essential modulator 0.0425 0.144
PLEK PLEK, P47: Pleckstrin 0.0425 0.144
TLK1 TLK1, KIAA0137: Serine/threonine-protein kinase tousled-like 1 0.0425 0.144
NRAS HRAS, HRAS1: GTPase HRas precursor 0.042 0.086
TOB1 TOB1, TOB, TROB1: Protein Tob1 0.042 0.053
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.041 0.054
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.041 0.032
RAC1 RAC1, MIG5: Ras-related C3 botulinum toxin substrate 1 precursor 0.0407 0.138
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.041 0.067
FBXL8 FBXL8, FBL8: F-box/LRR-repeat protein 8 0.041 0.083
SP140 SP140, LYSP100: Nuclear body protein SP140 0.041 0.050
RHOC RHOC, ARH9, ARHC: Rho-related GTP-binding protein RhoC precursor 0.040 0.040
RAB21 RAB21, KIAA0118: Ras-related protein Rab-21 0.040 0.040
SMARCA4 SMARCA4, BRG1, SNF2B, SNF2L4: Probable global transcription activator SNF2L4 0.039 0.0971
HIST3H3 HIST3H3, H3FT: Histone H3.1t 0.038 0.038
NEK9 NEK9, KIAA1995, NEK8, NERCC: Serine/threonine-protein kinase Nek9 0.038 0.129
SFRS4 SFRS4, SRP75: Splicing factor, arginine/serine-rich 4 0.038 0.129
NUP153 N/A 0.038 0.129
DDX3Y DDX3Y, DBY: ATP-dependent RNA helicase DDX3Y 0.038 0.063
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.038 0.129
NAP1L1 NAP1L1, NRP: Nucleosome assembly protein 1-like 1 0.038 0.078
EIF3S4 EIF3S4: Eukaryotic translation initiation factor 3 subunit 4 0.038 0.129
H3F3A H3F3A, H3.3A, PP781, H3.3B, H3F3B, H3F3: Histone H3.3 0.038 0.078
SFRS2 SFRS2: Splicing factor, arginine/serine-rich 2 0.038 0.129
STK10 STK10: Uncharacterized protein STK10 0.038 0.129
RELA RELA, NFKB3: Transcription factor p65 0.038 0.046
ZFP36 ZFP36, G0S24, RNF162A, TIS11A, TTP: Tristetraproline 0.038 0.046
TAOK3 TAOK3, DPK, JIK, KDS, MAP3K18: Serine/threonine-protein kinase TAO3 0.038 0.129
SKIIP SNW1, SKIIP, SKIP: SNW domain-containing protein 1 0.038 0.129
RPS6KB2 RPS6KB2, STK14B: Ribosomal protein S6 kinase beta-2 0.038 0.063
SMARCA5 SMARCA5, SNF2H, WCRF135: SWI/SNF-related matrix-associated actin-dependent regul 0.038 0.129
SNRPD3 SNRPD3: Small nuclear ribonucleoprotein Sm D3 0.038 0.129
EIF4G2 EIF4G2, DAP5, OK/SW-cl.75: Eukaryotic translation initiation factor 4 gamma 2 0.038 0.129
SFRS1 SFRS1, ASF, OK/SW-cl.3, SF2, SF2P33: Splicing factor, arginine/serine-rich 1 0.038 0.129
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.038 0.046
CBX3 CBX3: Chromobox protein homolog 3 0.038 0.129
DOK1 DOK1: Docking protein 1 0.038 0.063
TMEM1 TMEM1, EHOC1: Transmembrane protein 1 0.038 0.129
MRE11A MRE11A, HNGS1, MRE11: Double-strand break repair protein MRE11A 0.038 0.063
SF3B4 SF3B4, SAP49: Splicing factor 3B subunit 4 0.038 0.078
RCP9 CRCP: DNA-directed RNA polymerase III subunit RPC9 0.038 0.029
GTF2B GTF2B, TF2B, TFIIB: Transcription initiation factor IIB 0.038 0.078
DDX51 DDX51: ATP-dependent RNA helicase DDX51 0.038 0.129
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.038 0.046
AGTPBP1 AGTPBP1, RP11-30C23.1-005, hCG_1743691: AGTPBP1 protein 0.038 0.078
WDR44 WDR44: WD repeat-containing protein 44 0.038 0.063
SNRK SNRK, KIAA0096, SNFRK: SNF-related serine/threonine-protein kinase 0.038 0.029
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.038 0.078
RBM15 RBM15, OTT: Putative RNA-binding protein 15 0.038 0.129
APEX1 APEX1, APE, APEX, APX, HAP1, REF1: DNA-(apurinic or apyrimidinic site) lyase 0.038 0.078
SKIV2L SKIV2L, XXbac-BCX116I9.5-001, XXbac-BPG116M5.1-001: Superkiller viralicidic acti 0.038 0.063
SMC1L1 SMC1A, DXS423E, KIAA0178, SB1.8, SMC1, SMC1L1: Structural maintenance of chromos 0.038 0.129
CCNL1 CCNL1, BM-001, UNQ530/PRO1073: Cyclin-L1 0.038 0.063
SYNCRIP SYNCRIP, HNRPQ, NSAP1: Heterogeneous nuclear ribonucleoprotein Q 0.038 0.276
CSPG6 SMC3, BAM, BMH, CSPG6, SMC3L1: Structural maintenance of chromosomes protein 3 0.038 0.129
KIAA0788 ASCC3L1, HELIC2, KIAA0788: U5 small nuclear ribonucleoprotein 200 kDa helicase 0.038 0.129
ZNF330 ZNF330, NOA36: Zinc finger protein 330 0.038 0.129
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.038 0.276
PHF10 N/A 0.038 0.063
TOPBP1 TOPBP1, KIAA0259: DNA topoisomerase 2-binding protein 1 0.038 0.129
HIF1A HIF1A, MOP1: Hypoxia-inducible factor 1 alpha 0.038 0.063
CUL5 CUL5, VACM1: Cullin-5 0.038 0.078
HNRPF HNRPF: Heterogeneous nuclear ribonucleoprotein F 0.038 0.276
SPEN SPEN, KIAA0929, MINT, SHARP: Msx2-interacting protein 0.038 0.063
CSTF2T CSTF2T, KIAA0689: Cleavage stimulation factor 64 kDa subunit, tau variant 0.038 0.078
GGCX GGCX, GC: Vitamin K-dependent gamma-carboxylase 0.038 0.038
STAT5B STAT5B: Signal transducer and activator of transcription 5B 0.038 0.063
TIAL1 TIAL1: Nucleolysin TIAR 0.038 0.129
PABPN1 PABPN1, PAB2, PABP2: Polyadenylate-binding protein 2 0.038 0.129
KIAA0683 DKFZp434A073, DKFZp434I062, KIAA0683, TELO2, hCG_42688: Putative uncharacterized 0.038 0.063
HDAC3 HDAC3: Histone deacetylase 3 0.038 0.129
DIAPH1 Diaphanous 1 0.038 0.129
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.038 0.129
PABPC1 PABPC1, PAB1, PABP1, PABPC2: Polyadenylate-binding protein 1 0.038 0.078
KLHDC4 N/A 0.038 0.078
CUL4B N/A 0.038 0.078
SFRS6 SFRS6, SRP55: Splicing factor, arginine/serine-rich 6 0.038 0.078
NFKBIA NFKBIA, IKBA, MAD3, NFKBI: NF-kappa-B inhibitor alpha 0.038 0.046
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.038 0.078
RAB32 RAB32: Ras-related protein Rab-32 0.037 0.046
GAS2 GAS2: Growth arrest-specific protein 2 0.037 0.061
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.037 0.057
CNN3 CNN3: Calponin-3 0.037 0.037
RAB13 RAB13, GIG4: Ras-related protein Rab-13 0.037 0.037
SAFB2 SAFB2, KIAA0138: Scaffold attachment factor B2 0.036 0.101
RAB27B RAB27B: Ras-related protein Rab-27B 0.036 0.026
FBXL11 FBXL11, FBL7, JHDM1A, KIAA1004: JmjC domain-containing histone demethylation pro 0.036 0.074
ARF1 ARF1: ADP-ribosylation factor 1 0.036 0.074
ACTN4 ACTN4: Alpha-actinin-4 0.036 0.036
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.036 0.036
CLASP1 CLASP1, KIAA0622, MAST1: CLIP-associating protein 1 0.035 0.046
EIF4G3 EIF4G3: Eukaryotic translation initiation factor 4 gamma 3 0.035 0.038
FBXL14 FBXL14, FBL14: F-box/LRR-repeat protein 14 0.035 0.059
RAB2 RAB2, RAB2A: Ras-related protein Rab-2A 0.035 0.059
RAP2C RAP2C: Ras-related protein Rap-2c precursor 0.035 0.059
FBXL4 FBXL4, FBL4, FBL5: F-box/LRR-repeat protein 4 0.035 0.059
DLK1 DLK1, DLK: Delta-like protein precursor 0.034 0.034
RAD18 RAD18, RNF73: E3 ubiquitin-protein ligase RAD18 0.034 0.034
ATXN7 ATXN7, SCA7: Ataxin-7 0.033 0.0407
WWOX WWOX, FOR, WOX1: WW domain-containing oxidoreductase 0.033 0.051
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.033 0.026
SET SET: Protein SET 0.032 0.087
PASK PASK, KIAA0135: PAS domain-containing serine/threonine-protein kinase 0.032 0.0425
API5 N/A 0.032 0.087
RBM6 RBM6, DEF3: RNA-binding protein 6 0.032 0.052
ID2 ID2: DNA-binding protein inhibitor ID-2 0.032 0.087
XRCC4 N/A 0.032 0.032
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.032 0.026
MDM4 MDM4, MDMX: Mdm4 protein 0.032 0.026
CHD4 CHD4: Chromodomain-helicase-DNA-binding protein 4 0.032 0.144
VIM VIM: Vimentin 0.032 0.0425
ARFGAP1 N/A 0.032 0.070
MAPK7 mitogen-activated protein kinase 7 isoform 1 0.032 0.052
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.032 0.070
BRCA2 BRCA2, FACD, FANCD1: Breast cancer type 2 susceptibility protein 0.032 0.032
CDKN2D CDKN2D: Cyclin-dependent kinase 4 inhibitor D 0.032 0.052
TP53BP1 TP53BP1: Tumor suppressor p53-binding protein 1 0.032 0.052
EMD EMD, EDMD, STA: Emerin 0.032 0.052
ZNF638 ZNF638, NP220, ZFML: Zinc finger protein 638 0.032 0.087
SMARCC2 N/A 0.032 0.052
NEK1 NEK1, KIAA1901: Serine/threonine-protein kinase Nek1 0.032 0.026
MAPKAPK2 MAPKAPK2: MAP kinase-activated protein kinase 2 0.032 0.052
MYBBP1A MYBBP1A, P160: Myb-binding protein 1A 0.032 0.070
RNPS1 RNPS1, LDC2: RNA-binding protein with serine-rich domain 1 0.032 0.087
ABCF1 N/A 0.032 0.144
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.032 0.052
MAP3K14 MAP3K14, NIK: Mitogen-activated protein kinase kinase kinase 14 0.032 0.0425
PPP1CB PPP1CB: Serine/threonine-protein phosphatase PP1-beta catalytic subunit 0.032 0.040
SEC24B SEC24B: Protein transport protein Sec24B 0.032 0.066
RHOF RHOF, ARHF, RIF: Rho-related GTP-binding protein RhoF precursor 0.032 0.108
RAB7L1 RAB7L1: Ras-related protein Rab-7L1 0.032 0.065
RHOQ RHOQ, ARHQ, RASL7A, TC10: Rho-related GTP-binding protein RhoQ precursor 0.032 0.039
KRAS N/A 0.032 0.108
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.031 0.031
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.0308 0.0308
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 0.0308 0.035
F7 F7: Coagulation factor VII precursor 0.030 0.030
KCNH2 KCNH2, ERG, ERG1, HERG, HERG1: Potassium voltage-gated channel subfamily H membe 0.030 0.030
JAG2 JAG2: Jagged-2 precursor 0.030 0.030
SF3A3 SF3A3, SAP61: Splicing factor 3A subunit 3 0.030 0.061
RAB11B RAB11B, YPT3: Ras-related protein Rab-11B 0.030 0.036
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.029 0.026
DIRAS3 DIRAS3, ARHI, NOEY2, RHOI: GTP-binding protein Di-Ras3 0.029 0.029
RIMS1 RIMS1, KIAA0340, Nbla00761, RAB3IP2, RIM1: Regulating synaptic membrane exocytos 0.029 0.026
SNRPB2 SNRPB2: U2 small nuclear ribonucleoprotein B'' 0.029 0.129
CRSP2 MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170: Mediator of RNA pol 0.029 0.038
LSM2 LSM2, C6orf28, G7b: U6 snRNA-associated Sm-like protein LSm2 0.029 0.063
SNRPD1 SNRPD1: Small nuclear ribonucleoprotein Sm D1 0.029 0.078
CTDP1 CTDP1, FCP1: RNA polymerase II subunit A C-terminal domain phosphatase 0.029 0.046
SNRP70 SNRP70, RNPU1Z, RPU1, U1AP1: U1 small nuclear ribonucleoprotein 70 kDa 0.029 0.063
TCF3 TCF3, E2A, ITF1: Transcription factor E2-alpha 0.029 0.063
ANP32B ANP32B, APRIL, PHAPI2: Acidic leucine-rich nuclear phosphoprotein 32 family memb 0.029 0.078
TOPORS TOPORS, LUN, TP53BPL: E3 ubiquitin-protein ligase Topors 0.029 0.063
GSK3B N/A 0.029 0.078
FZR1 N/A 0.029 0.038
SEC24C SEC24C, KIAA0079: Protein transport protein Sec24C 0.029 0.129
ELAVL1 ELAVL1, HUR: ELAV-like protein 1 0.029 0.129
RBMX2 RBMX2, CGI-79: RNA-binding motif protein, X-linked 2 0.029 0.046
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.029 0.129
SSB SSB: Lupus La protein 0.029 0.078
RUNX1 N/A 0.029 0.029
HDAC2 HDAC2: Histone deacetylase 2 0.029 0.063
PABPC4 PABPC4, APP1, PABP4: Polyadenylate-binding protein 4 0.029 0.078
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.029 0.046
CRKRS CRKRS, CRK7, KIAA0904: Cell division cycle 2-related protein kinase 7 0.029 0.046
UBA2 SAE2, UBA2, HRIHFB2115, UBLE1B: SUMO-activating enzyme subunit 2 0.029 0.078
CPSF1 CPSF1, CPSF160: Cleavage and polyadenylation specificity factor subunit 1 0.029 0.063
CDK2 CDK2: Cell division protein kinase 2 0.029 0.046
WEE1 WEE1: Wee1-like protein kinase 0.029 0.038
AHR AHR: Aryl hydrocarbon receptor precursor 0.029 0.038
DAXX DAXX, BING2, DAP6: Death domain-associated protein 6 0.029 0.063
ANAPC5 ANAPC5, APC5: Anaphase-promoting complex subunit 5 0.029 0.129
EIF3S9 EIF3S9: Eukaryotic translation initiation factor 3 subunit 9 0.029 0.078
SAPS3 N/A 0.029 0.063
MTA1 MTA1: Metastasis-associated protein MTA1 0.029 0.063
HTATSF1 HTATSF1: HIV Tat-specific factor 1 0.029 0.046
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.029 0.078
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.029 0.129
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.029 0.078
TAF10 TAF2A, TAF10, TAF2H, TAFII30: Transcription initiation factor TFIID subunit 10 0.029 0.078
KCTD12 KCTD12, C13orf2, KIAA1778, PFET1: BTB/POZ domain-containing protein KCTD12 0.029 0.029
WBSCR20A N/A 0.029 0.078
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.029 0.046
CDKN1B CDKN1B, KIP1: Cyclin-dependent kinase inhibitor 1B 0.029 0.046
STAT4 STAT4: Signal transducer and activator of transcription 4 0.029 0.038
RBM7 0.029 0.063
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.029 0.063
DUSP22 DUSP22, JSP1, MKPX: Dual specificity protein phosphatase 22 0.029 0.063
LMNB1 LMNB1, LMN2, LMNB: Lamin-B1 0.029 0.078
TRIM25 TRIM25, EFP, RNF147, ZNF147: Tripartite motif-containing protein 25 0.029 0.029
TIMELESS TIMELESS, TIM, TIM1, TIMELESS1: Protein timeless homolog 0.029 0.038
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.029 0.046
HIST1H3A HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, 0.029 0.038
EIF2S1 EIF2S1, EIF2A: Eukaryotic translation initiation factor 2 subunit 1 0.029 0.129
EIF2B5 EIF2B5, EIF2BE: Translation initiation factor eIF-2B subunit epsilon 0.029 0.063
MYH9 MYH9: Myosin-9 0.029 0.063
EXOSC2 EXOSC2, RRP4: Exosome complex exonuclease RRP4 0.029 0.046
NRBP1 NRBP1, BCON3, NRBP: Nuclear receptor-binding protein 0.029 0.063
CCNH CCNH: Cyclin-H 0.029 0.046
RAB14 RAB14: Ras-related protein Rab-14 0.029 0.0968
RALB RALB: Ras-related protein Ral-B precursor 0.029 0.035
RAP2B RAP2B: Ras-related protein Rap-2b precursor 0.029 0.0968
DRG2 DRG2: Developmentally-regulated GTP-binding protein 2 0.029 0.0968
WWP1 WWP1: NEDD4-like E3 ubiquitin-protein ligase WWP1 0.029 0.059
MAPKAPK5 N/A 0.028 0.028
KIF1B N/A 0.028 0.028
AR AR, DHTR, NR3C4: Androgen receptor 0.028 0.028
JDP2 jdp2, JDP2: Jun dimerization protein 2 0.028 0.028
BMP2K BMP2K, BIKE, HRIHFB2017: BMP-2-inducible protein kinase 0.028 0.028
CBFA2T2 CBFA2T2, EHT, MTGR1: Protein CBFA2T2 0.028 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.028 0.028
C14orf151 C14orf151: Uncharacterized protein C14orf151 (Fragment) 0.028 0.028
CABLES1 N/A 0.028 0.028
HNRPC HNRPC: Heterogeneous nuclear ribonucleoproteins C1/C2 0.028 0.028
SMARCAD1 SMARCAD1, KIAA1122: SWI/SNF-related matrix-associated actin-dependent regulator 0.028 0.028
DSP DSP: Desmoplakin 0.028 0.028
IRF7 N/A 0.028 0.028
NFIA NFIA, RP5-902P15.1-003, hCG_2032260: Nuclear factor I/A 0.028 0.028
GPRASP2 GPRASP2: G-protein coupled receptor-associated sorting protein 2 0.028 0.028
PTBP1 PTBP1: Polypyrimidine tract binding protein 1 0.028 0.028
PPP1R12C PPP1R12C, MBS85: Protein phosphatase 1 regulatory subunit 12C 0.028 0.028
ZNF265 N/A 0.028 0.028
ARNT ARNT: Aryl hydrocarbon receptor nuclear translocator 0.028 0.028
HDAC8 N/A 0.028 0.028
SGK2 SGK2: Serine/threonine-protein kinase Sgk2 0.028 0.028
TMPO TMPO, LAP2: Lamina-associated polypeptide 2 isoform alpha 0.028 0.028
DYRK1A DYRK1A, DYRK, MNB, MNBH: Dual specificity tyrosine-phosphorylation-regulated kin 0.028 0.028
MLL2 MLL2, ALR: Myeloid/lymphoid or mixed-lineage leukemia protein 2 0.028 0.028
MITF MITF: Microphthalmia-associated transcription factor 0.028 0.028
CDC2L2 CDC2L2, CDC2L3, PITSLREB: PITSLRE serine/threonine-protein kinase CDC2L2 0.028 0.028
PHLDB2 N/A 0.028 0.028
ILF3 ILF3, DRBF, MPHOSPH4, NF90: Interleukin enhancer-binding factor 3 0.028 0.028
ZNF687 ZNF687, KIAA1441: Zinc finger protein 687 0.028 0.028
C13orf8 N/A 0.028 0.028
NFATC2 NFATC2, NFAT1, NFATP: Nuclear factor of activated T-cells, cytoplasmic 2 0.028 0.028
NF2 NF2, SCH: Merlin 0.028 0.028
FLJ21816 PALB2, FANCN: Partner and localizer of BRCA2 0.028 0.028
ZCCHC3 ZCCHC3, C20orf99: Zinc finger CCHC domain-containing protein 3 0.028 0.028
BID BID: BH3-interacting domain death agonist 0.028 0.028
NSBP1 NSBP1: Nucleosome-binding protein 1 0.028 0.028
RAVER1 RAVER1, KIAA1978: Ribonucleoprotein PTB-binding 1 0.028 0.028
DUSP15 N/A 0.028 0.028
TCF20 TCF20, KIAA0292, SPBP: Transcription factor 20 0.028 0.028
ZC3HAV1 ZC3HAV1, ZC3HDC2, PRO1677: Zinc finger CCCH type antiviral protein 1 0.028 0.028
CORO6 N/A 0.028 0.028
ATXN2L ATXN2L, A2D, A2LG, A2LP, A2RP: Ataxin-2-like protein 0.028 0.028
NFATC3 NFATC3, NFAT4: Nuclear factor of activated T-cells, cytoplasmic 3 0.028 0.028
NES N/A 0.028 0.028
PPEF1 N/A 0.028 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.028 0.028
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.028 0.028
DKFZp434K1815 DKFZp434K1815, hCG_1736780: Putative uncharacterized protein DKFZp434K1815 0.028 0.028
SNRPB N/A 0.028 0.028
LOC642558 FUSIP1, FUSIP2, TASR: FUS-interacting serine-arginine-rich protein 1 0.028 0.028
HES6 HES6: Transcription cofactor HES-6 0.028 0.028
CDC2L1 CDC2L1, PITSLREA, PK58: PITSLRE serine/threonine-protein kinase CDC2L1 0.028 0.028
SKIL SKIL, SNO: Ski-like protein 0.028 0.028
RAB8B RAB8B: Ras-related protein Rab-8B 0.028 0.060
SAR1A SAR1A, SAR1, SARA, SARA1: GTP-binding protein SAR1a 0.028 0.044
RAB35 RAB35, RAB1C, RAY: Ras-related protein Rab-35 0.028 0.074
ARL4C ARL7: ADP ribosylation factor-like protein 7 0.028 0.060
FBXO11 FBXO11, FBX11, VIT1: F-box only protein 11 0.028 0.028
ARL1 ARL1: ADP-ribosylation factor-like protein 1 0.028 0.036
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.027 0.067
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.027 0.027
ACTN1 ACTN1: Alpha-actinin-1 0.027 0.027
MAPRE2 MAPRE2, RP1: Microtubule-associated protein RP/EB family member 2 0.027 0.054
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.027 0.054
ATAD2 ATAD2, L16, PRO2000: ATPase family AAA domain-containing protein 2 0.027 0.041
FBXO22 FBXO22, FBX22: F-box only protein 22 0.027 0.027
FOXQ1 FOXQ1, HFH1: Forkhead box protein Q1 0.027 0.027
FBXO18 FBXO18, FBH1, FBX18: F-box only protein 18 0.027 0.027
FBXO8 FBXO8, FBS, DC10, FBX8, UNQ1877/PRO4320: F-box only protein 8 0.027 0.027
FBXL3 FBXL3, FBL3A, FBXL3A: F-box/LRR-repeat protein 3 0.027 0.027
ZNF395 FBXO16, FBX16: F-box only protein 16 0.027 0.027
FBXW8 FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6: F-box/WD repeat-containing protein 8 0.027 0.027
FBXO46 FBXO46, FBX46, FBXO34L: F-box only protein 46 0.027 0.027
FBXO39 FBXO39, FBX39: F-box only protein 39 0.027 0.027
FBXO30 FBXO30, FBX30: F-box only protein 30 0.027 0.027
ARL11 ARL11, ARLTS1: ADP-ribosylation factor-like protein 11 0.027 0.027
FBXO36 FBXO36, FBX36: F-box only protein 36 0.027 0.027
FBXO15 FBXO15, FBX15: F-box only protein 15 0.027 0.027
FBXO24 N/A 0.027 0.027
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.027 0.036
DAPP1 N/A 0.027 0.036
CASP8 N/A 0.027 0.036
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.027 0.0446
RAB3A RAB3A: Ras-related protein Rab-3A 0.0264 11.20
SF3A1 SF3A1, SAP114: Splicing factor 3 subunit 1 0.026 0.072
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.026 0.029
ICK ICK, KIAA0936: Serine/threonine-protein kinase ICK 0.026 0.026
TRAFD1 TRAFD1, FLN29: TRAF-type zinc finger domain-containing protein 1 0.026 0.070
IRS2 IRS2: Insulin receptor substrate 2 0.026 0.032
EIF4G1 EIF4G1, EIF4F, EIF4G, EIF4GI: Eukaryotic translation initiation factor 4 gamma 1 0.026 0.070
RXRA RXRA, NR2B1: Retinoic acid receptor RXR-alpha 0.026 0.032
TCOF1 N/A 0.026 0.087
AOF2 AOF2, KIAA0601, LSD1: Lysine-specific histone demethylase 1 0.026 0.052
ID3 ID3, 1R21, HEIR-1: DNA-binding protein inhibitor ID-3 0.026 0.026
RDBP RDBP, NELFE, RD: Negative elongation factor E 0.026 0.052
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.026 0.046
MECP2 MECP2: Methyl-CpG-binding protein 2 0.026 0.0425
COIL COIL, CLN80: Coilin 0.026 0.0425
ITGB1BP1 ITGB1BP1, ICAP1: Integrin beta-1-binding protein 1 0.026 0.087
GTF3C1 N/A 0.026 0.070
PRKAA1 N/A 0.026 0.032
XRCC1 XRCC1: DNA-repair protein XRCC1 0.026 0.070
DNMT1 DNMT1, AIM, DNMT: DNA 0.026 0.070
MAP2K3 MAP2K3, MEK3, MKK3, PRKMK3: Dual specificity mitogen-activated protein kinase ki 0.026 0.032
CENPA CENPA: Histone H3-like centromeric protein A 0.026 0.052
STK16 N/A 0.026 0.0425
TRRAP N/A 0.026 0.052
UBAP2 N/A 0.026 0.052
SMARCA3 HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1: Helicase-like transcription factor 0.026 0.032
KIF22 KIF22, KID, KNSL4: Kinesin-like protein KIF22 0.026 0.032
CIC CIC, KIAA0306: Protein capicua homolog 0.025 0.031
BCOR N/A 0.025 0.025
NCOA3 NCOA3, AIB1, RAC3, TRAM1: Nuclear receptor coactivator 3 0.025 0.025
LMNA LMNA, LMN1: Lamin-A/C 0.025 0.025
CAMKK1 N/A 0.025 0.025
NEDD4 NEDD4: Uncharacterized protein NEDD4 0.025 0.025
GATAD2B GATAD2B, KIAA1150: Transcriptional repressor p66 beta 0.025 0.025
PHF16 PHF16, JADE3, KIAA0215: Protein Jade-3 0.025 0.025
CDC25C CDC25C: M-phase inducer phosphatase 3 0.025 0.025
WNK4 WNK4, PRKWNK4: Serine/threonine-protein kinase WNK4 0.025 0.025
SMARCA2 SMARCA2, BRM, SNF2A, SNF2L2: Probable global transcription activator SNF2L2 0.025 0.025
SSBP4 SSBP4: Single-stranded DNA-binding protein 4 0.025 0.025
ARID4A ARID4A, RBBP1, RBP1: AT-rich interactive domain-containing protein 4A 0.025 0.025
HNRPM HNRPM, NAGR1: Heterogeneous nuclear ribonucleoprotein M 0.025 0.025
C14orf4 C14orf4, KIAA1865, My039: RING finger protein C14orf4 0.025 0.025
MAPK8IP3 N/A 0.025 0.025
DHX8 DHX8, DDX8: ATP-dependent RNA helicase DHX8 0.025 0.025
EDF1 EDF1: Endothelial differentiation-related factor 1 0.025 0.025
PSIP1 PSIP1, DFS70, LEDGF, PSIP2: PC4 and SFRS1-interacting protein 0.025 0.025
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.025 0.025
CDC2 CDC2: Cell division control protein 2 homolog 0.025 0.025
HEXIM2 HEXIM2, L3: Protein HEXIM2 0.025 0.025
MSL3L1 MSL3L1: Male-specific lethal 3-like 1 0.025 0.025
SYAP1 SYAP1, PRO3113: Synapse-associated protein 1 0.025 0.025
NFYA NFYA: Nuclear transcription factor Y subunit alpha 0.025 0.025
PRKACA PRKACA, PKACA: cAMP-dependent protein kinase, alpha-catalytic subunit 0.025 0.025
PRKCB1 N/A 0.025 0.025
SMC4L1 SMC4, CAPC, SMC4L1: Structural maintenance of chromosomes protein 4 0.025 0.025
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.025 0.025
ADK ADK: Adenosine kinase 0.025 0.025
HIST2H2AC HIST2H2AC, H2AFQ: Histone H2A type 2-C 0.025 0.025
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.025 0.025
RAD51 RAD51, RAD51A, RECA: DNA repair protein RAD51 homolog 1 0.025 0.025
GRK6 N/A 0.025 0.025
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.025 0.025
PPP1R9B PPP1R9B, PPP1R6: Neurabin-2 0.025 0.025
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.025 0.025
SETD3 SETD3, C14orf154: SET domain-containing protein 3 0.025 0.025
RBBP6 RBBP6, P2PR, My038, PACT, RBQ1: Retinoblastoma-binding protein 6 0.025 0.025
MKNK2 MKNK2, GPRK7, MNK2: MAP kinase-interacting serine/threonine-protein kinase 2 0.025 0.025
ARID1A ARID1A, C1orf4, OSA1, SMARCF1: AT-rich interactive domain-containing protein 1A 0.025 0.025
CPNE1 RBM12, KIAA0765, HRIHFB2091: RNA-binding protein 12 0.025 0.025
HNRPD HNRPD, AUF1: Heterogeneous nuclear ribonucleoprotein D0 0.025 0.025
POLR1C POLR1C, POLR1E: DNA-directed RNA polymerases I and III subunit RPAC1 0.025 0.025
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.025 0.025
NUP98 N/A 0.025 0.025
MLL4 WBP7, HRX2, KIAA0304, MLL2, MLL4, TRX2: WW domain-binding protein 7 0.025 0.025
EXO1 EXO1, EXOI, HEX1: Exonuclease 1 0.025 0.025
SAP14 SF3B14, CGI-110, HSPC175, HT006: Pre-mRNA branch site protein p14 0.025 0.025
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.025 0.025
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.025 0.025
ZNF598 ZNF598: Zinc finger protein 598 0.025 0.025
TFAP4 TFAP4: Transcription factor AP-4 0.025 0.025
HNRPA2B1 HNRPA2B1: Heterogeneous nuclear ribonucleoproteins A2/B1 0.025 0.025
IWS1 IWS1, IWS1L: IWS1 homolog 0.025 0.025
RNF113A RNF113A, RNF113, ZNF183: RING finger protein 113A 0.025 0.025
TAL2 TAL2: T-cell acute lymphocytic leukemia protein 2 0.025 0.025
HIST3H2A HIST3H2A: Histone H2A type 3 0.025 0.025
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.025 0.025
HTATIP N/A 0.025 0.025
RNF20 0.025 0.025
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.025 0.025
CDC25A CDC25A: M-phase inducer phosphatase 1 0.025 0.025
SON 0.025 0.025
NSUN2 NSUN2, SAKI, TRM4: tRNA 0.025 0.025
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 0.025 0.025
ATRX ATRX, RAD54L, XH2: Transcriptional regulator ATRX 0.025 0.025
GIT2 N/A 0.025 0.025
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.025 0.025
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.025 0.025
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.025 0.025
SFRS9 SFRS9, SRP30C: Splicing factor, arginine/serine-rich 9 0.025 0.025
MKI67IP MKI67IP, NIFK, NOPP34: MKI67 FHA domain-interacting nucleolar phosphoprotein 0.025 0.025
KCTD1 0.025 0.025
FLJ23436 N/A 0.025 0.025
MLXIPL MLXIPL, MIO, WBSCR14: Williams-Beuren syndrome chromosome region 14 protein 0.025 0.025
EEF2K EEF2K: Elongation factor 2 kinase 0.025 0.025
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.025 0.025
CCNT2 CCNT2: Cyclin-T2 0.025 0.025
FAF1 FAF1, CGI-03: FAS-associated factor 1 0.025 0.025
CAMK2A N/A 0.025 0.025
SMN2 SMN1, SMN, SMN2, SMNC, SMNT: Survival motor neuron protein 0.025 0.025
RPS6KA4 RPS6KA4, MSK2: Ribosomal protein S6 kinase alpha-4 0.025 0.025
MAX MAX: Protein max 0.025 0.025
DYRK1B DYRK1B, MIRK: Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0.025 0.025
MIER1 MIER1, KIAA1610: Mesoderm induction early response protein 1 0.025 0.025
DIDO1 N/A 0.025 0.025
CETN1 CETN1, CEN1, CETN: Centrin-1 0.025 0.025
ELMO1 N/A 0.025 0.025
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.025 0.025
TCEA1 N/A 0.025 0.025
MKNK1 MKNK1, MNK1: MAP kinase-interacting serine/threonine-protein kinase 1 0.025 0.025
SEC13L1 N/A 0.025 0.025
DDX20 DDX20, DP103, GEMIN3: Probable ATP-dependent RNA helicase DDX20 0.025 0.025
MAP3K7 MAP3K7, TAK1: Mitogen-activated protein kinase kinase kinase 7 0.025 0.025
RPS6KA2 RPS6KA2, RSK3: Ribosomal protein S6 kinase alpha-2 0.025 0.025
CARHSP1 CARHSP1: Calcium-regulated heat stable protein 1 0.025 0.025
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.025 0.025
PDE8B PDE8B: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodies 0.025 0.025
CAMK1D CAMK1D: Calcium/calmodulin-dependent protein kinase type 1D 0.025 0.025
HDAC7A N/A 0.025 0.025
FLJ40432 FLJ40432, hCG_2036624: CDNA FLJ40432 fis, clone TESTI2039227 0.025 0.025
ATXN2L N/A 0.025 0.025
PURB PURB: Transcriptional activator protein Pur-beta 0.025 0.025
HNRPUL1 HNRPUL1, E1BAP5: Heterogeneous nuclear ribonucleoprotein U-like protein 1 0.025 0.025
TIA1 TIA1: Nucleolysin TIA-1 isoform p40 0.025 0.025
REXO1 REXO1, ELOABP1, KIAA1138, TCEB3BP1: RNA exonuclease 1 homolog 0.025 0.025
NHN1 NHN1: Conserved nuclear protein NHN1 0.025 0.025
C20orf77 N/A 0.025 0.025
MAP2K3 N/A 0.025 0.025
0.347
Total Score 19.20