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Evidence of Interaction Between PDGFRB and SRC

The interaction score between PDGFRB and SRC is 167.00.

This page provides the details about the evidence that was used to calculate the interaction Score between the two proteins

The Scores that are listed with each module are based on the interaction score where that module provides the only source of evidence. The final Score is the integration of all the sources of evidence.

FeatureEvidenceScore (?)
Gene Expression

Pearson's Correlation between PDGFRB and SRC = 0.06

The original expression data was collated from the NCBI GEO database. For further information about this dataset please refer to the NCBI GEO dataset GDS596.

 1.85E-3
Orthology N/A N/A
Domains Domains present in PDGFRB and SRC:
Domains in PDGFRBDomains in SRC
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR011009 Protein kinase-like
IPR003598 Immunoglobulin C-2 type
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like
IPR001824 Receptor tyrosine kinase, class III
IPR009134 Vascular endothelial growth factor receptor, VEGFR
IPR013151 Immunoglobulin.
IPR000719 Protein kinase
IPR001245 Tyrosine protein kinase
IPR008266 Tyrosine protein kinase, active site
IPR001452 SH3
IPR000980 SH2 motif

The Chi square scores for co-occurrence of domains that are present in PDGFRB and SRC are listed below.

Domain 1Domain 2Chi Square
IPR008266 Tyrosine protein kinase, active site IPR000980 SH2 motif 383.26
IPR001245 Tyrosine protein kinase IPR000980 SH2 motif 238.73
IPR008266 Tyrosine protein kinase, active site IPR001452 SH3 164.706
IPR001824 Receptor tyrosine kinase, class III IPR000980 SH2 motif 101.074
IPR001245 Tyrosine protein kinase IPR001452 SH3 100.857
IPR007110 Immunoglobulin-like IPR000980 SH2 motif 94.9752
IPR000719 Protein kinase IPR000980 SH2 motif 82.1364
IPR003599 Immunoglobulin subtype IPR000980 SH2 motif 66.4833
IPR003598 Immunoglobulin C-2 type IPR000980 SH2 motif 64.7072
IPR011009 Protein kinase-like IPR000980 SH2 motif 59.6059
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000980 SH2 motif 49.095
IPR013151 Immunoglobulin. IPR000980 SH2 motif 36.9251
IPR001824 Receptor tyrosine kinase, class III IPR001452 SH3 32.2626
IPR000719 Protein kinase IPR000719 Protein kinase 30.6895
IPR000719 Protein kinase IPR001452 SH3 27.1334
IPR003598 Immunoglobulin C-2 type IPR001452 SH3 26.0449
IPR003599 Immunoglobulin subtype IPR001452 SH3 22.2905
IPR011009 Protein kinase-like IPR001452 SH3 20.4416
IPR007110 Immunoglobulin-like IPR001452 SH3 20.3228
IPR003598 Immunoglobulin C-2 type IPR008266 Tyrosine protein kinase, active site 15.3939
IPR013151 Immunoglobulin. IPR001452 SH3 14.5395
IPR007110 Immunoglobulin-like IPR000719 Protein kinase 11.3335
IPR008266 Tyrosine protein kinase, active site IPR008266 Tyrosine protein kinase, active site 9.50479
IPR003599 Immunoglobulin subtype IPR008266 Tyrosine protein kinase, active site 8.71812
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR001452 SH3 8.64336
IPR007110 Immunoglobulin-like IPR008266 Tyrosine protein kinase, active site 8.13215
IPR000719 Protein kinase IPR008266 Tyrosine protein kinase, active site 6.98997
IPR003598 Immunoglobulin C-2 type IPR001245 Tyrosine protein kinase 4.5123
IPR001824 Receptor tyrosine kinase, class III IPR008266 Tyrosine protein kinase, active site 4.49385
IPR013151 Immunoglobulin. IPR008266 Tyrosine protein kinase, active site 4.11154
IPR003599 Immunoglobulin subtype IPR000719 Protein kinase 3.60485
IPR011009 Protein kinase-like IPR000719 Protein kinase 2.94434
IPR000719 Protein kinase IPR001245 Tyrosine protein kinase 2.31134
IPR013151 Immunoglobulin. IPR000719 Protein kinase 1.81655
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR008266 Tyrosine protein kinase, active site 1.70807
IPR001824 Receptor tyrosine kinase, class III IPR001245 Tyrosine protein kinase 1.57698
IPR003599 Immunoglobulin subtype IPR001245 Tyrosine protein kinase 1.01254
IPR001245 Tyrosine protein kinase IPR008266 Tyrosine protein kinase, active site 0.959759
IPR013151 Immunoglobulin. IPR001245 Tyrosine protein kinase 0.63318
IPR007110 Immunoglobulin-like IPR001245 Tyrosine protein kinase 0.479454
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR001245 Tyrosine protein kinase 0.339832
IPR011009 Protein kinase-like IPR001245 Tyrosine protein kinase 0.178275
IPR003598 Immunoglobulin C-2 type IPR000719 Protein kinase 0.142823
IPR001245 Tyrosine protein kinase IPR001245 Tyrosine protein kinase 0.0451828
IPR011009 Protein kinase-like IPR008266 Tyrosine protein kinase, active site 0.00724826
IPR001824 Receptor tyrosine kinase, class III IPR000719 Protein kinase 0.000102653
IPR009134 Vascular endothelial growth factor receptor, VEGFR IPR000719 Protein kinase 0.0000462868

The background colour of the table refers to:

  • Blue Domain is only present in PDGFRB
  • Yellow Domain is only present in SRC
  • Green Domain is present in both PDGFRB and SRC

 0.980
Post-translational Modifications

Protein: PDGFRB

PTMResidueReference
Dephosphorylation 562 PubMed, HPRD
Dephosphorylation 579 PubMed, HPRD
Dephosphorylation 740 PubMed, HPRD
Dephosphorylation 751 PubMed, HPRD
Dephosphorylation 771 PubMed, HPRD
Dephosphorylation 857 PubMed, HPRD
Dephosphorylation 1009 PubMed, HPRD
Dephosphorylation 1021 PubMed, HPRD
Phosphorylation 579 PubMed, HPRD
Phosphorylation 581 PubMed, HPRD
Phosphorylation 716 PubMed, HPRD
Phosphorylation 740 PubMed, HPRD
Phosphorylation 751 PubMed, HPRD
Phosphorylation 763 PubMed, HPRD
Phosphorylation 771 PubMed, HPRD
Phosphorylation 775 PubMed, HPRD
Phosphorylation 857 PubMed, HPRD
Phosphorylation 1009 PubMed, HPRD
Phosphorylation 1021 PubMed, HPRD
Phosphotyrosine 751 PubMed, HPRD
Phosphotyrosine 857 PubMed, HPRD

Protein: SRC

PTMResidueReference
Dephosphorylation 338 PubMed, HPRD
Dephosphorylation 419 PubMed, HPRD
Dephosphorylation 530 PubMed, HPRD
Myristoylation 2 PubMed, HPRD
Phosphorylation 12 PubMed, HPRD
Phosphorylation 17 PubMed, HPRD
Phosphorylation 75 PubMed, HPRD
Phosphorylation 97 PubMed, HPRD
Phosphorylation 216 PubMed, HPRD
Phosphorylation 419 PubMed, HPRD
Phosphorylation 530 PubMed, HPRD
Phosphotyrosine 418 PubMed, HPRD
Phosphotyrosine 529 PubMed, HPRD
Localisation

Protein: PDGFRB

LocalisationReference
Plasma membrane HPRD

Protein: SRC

LocalisationReference
Nucleus HPRD
Plasma membrane HPRD
Cytoplasm HPRD
Transitive Score

The common interactors between PDGFRB and SRC that are considered by the Transitive module are listed below.

The Scores listed are the values used by the transitive module to calculate the final interaction Score between PDGFRB andSRC. The values listed are therefore not the final Score value for the listed interactions.

With a Score value ≥0.025 , PDGFRB has 1323 interactors and SRC has 1642 interactors of which there are 888 common interactors.

Common InteractorName of Common InteractorScore for PDGFRB-Interactor (?)Score for SRC-Interactor (?)
FYN FYN: Proto-oncogene tyrosine-protein kinase Fyn 1.01E3 1.30
NCK2 NCK2: Cytoplasmic protein NCK2 600.00 0.975
STAT5A STAT5A, STAT5: Signal transducer and activator of transcription 5A 600.00 1.20
CRKL CRKL: Crk-like protein 536.00 1.20
PDGFRA PDGFRA: Alpha-type platelet-derived growth factor receptor precursor 532.00 0.644
GRB2 GRB2, ASH: Growth factor receptor-bound protein 2 422.00 1.30
STAT5B STAT5B: Signal transducer and activator of transcription 5B 372.00 0.902
PIK3R2 PIK3R2: Phosphatidylinositol 3-kinase regulatory subunit beta 315.00 0.975
FGR FGR, SRC2: Proto-oncogene tyrosine-protein kinase FGR 281.00 1.50
GRAP2 GRAP2, GADS, GRB2L, GRID: GRB2-related adapter protein 2 281.00 0.859
VAV1 VAV1, VAV: Proto-oncogene vav 281.00 1.50
TEC TEC, PSCTK4: Tyrosine-protein kinase Tec 277.00 1.50
FRK FRK, PTK5, RAK: Tyrosine-protein kinase FRK 277.00 0.975
PLCG2 PLCG2: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 265.00 0.617
STAT6 STAT6: Signal transducer and activator of transcription 6 250.00 1.98
NCK1 NCK1, NCK: Cytoplasmic protein NCK1 250.00 1.20
HCK N/A 250.00 1.50
JAK2 JAK2: Tyrosine-protein kinase JAK2 250.00 1.50
STAT1 STAT1: Signal transducer and activator of transcription 1-alpha/beta 232.00 0.980
FLT1 FLT1, FLT, FRT: Vascular endothelial growth factor receptor 1 precursor 183.00 0.731
SHC3 SHC3, NSHC, SHCC: SHC-transforming protein 3 147.00 0.197
CBL CBL, CBL2, RNF55: E3 ubiquitin-protein ligase CBL 137.00 1.13
GRAP GRAP: GRB2-related adapter protein 133.00 0.244
CSF1R CSF1R, FMS: Macrophage colony-stimulating factor 1 receptor precursor 112.00 0.902
KIT KIT: Mast/stem cell growth factor receptor precursor 112.00 0.731
FRS3 FRS3: Fibroblast growth factor receptor substrate 3 84.00 0.191
KDR KDR, FLK1: Vascular endothelial growth factor receptor 2 precursor 82.20 0.644
PTK2 PTK2, FAK, FAK1: Focal adhesion kinase 1 74.00 0.859
JUP JUP, CTNNG, DP3: Junction plakoglobin 37.90 0.096
SHC2 N/A 29.70 0.0288
PRKCE PRKCE, PKCE: Protein kinase C epsilon type 15.80 0.152
PRKCA PRKCA, PKCA, PRKACA: Protein kinase C alpha type 12.50 0.109
PRKCG PRKCG, PKCG: Protein kinase C gamma type 12.50 0.109
SOCS7 SOCS7, NAP4, SOCS6: Suppressor of cytokine signaling 7 12.40 0.0288
ABL1 ABL1, ABL, JTK7: Proto-oncogene tyrosine-protein kinase ABL1 1.13 1.50
MATK MATK, CTK, HYL: Megakaryocyte-associated tyrosine-protein kinase 0.980 1.30
SLA2 SLA2, C20orf156, SLAP2: Src-like-adapter 2 0.980 1.30
ITK ITK, EMT, LYK: Tyrosine-protein kinase ITK/TSK 0.980 1.30
RASA1 RASA1, RASA: Ras GTPase-activating protein 1 0.980 1.30
LNK SH2B3, LNK: SH2B adapter protein 3 0.980 1.30
ABL2 ABL2, ABLL, ARG: Tyrosine-protein kinase ABL2 0.980 1.30
PTPN6 PTPN6, HCP, PTP1C: Tyrosine-protein phosphatase non-receptor type 6 0.980 1.30
KHDRBS1 KHDRBS1, SAM68: KH domain-containing, RNA-binding, signal transduction-associate 0.916 0.318
BMX N/A 0.902 1.20
STAT3 0.878 1.30
YES1 YES1, YES: Proto-oncogene tyrosine-protein kinase Yes 0.808 1.20
SH2D2A SH2D2A, SCAP, TSAD, VRAP: SH2 domain-containing protein 2A 0.731 0.859
INSL3 JAK3: Tyrosine-protein kinase JAK3 0.731 1.20
FER FER, TYK3: Proto-oncogene tyrosine-protein kinase FER 0.655 1.20
TYK2 TYK2: Non-receptor tyrosine-protein kinase TYK2 0.654 1.98
SLA SLA, SLAP, SLAP1: SRC-like-adapter 0.654 0.975
BTK BTK, AGMX1, ATK, BPK: Tyrosine-protein kinase BTK 0.654 1.98
SYK SYK: Tyrosine-protein kinase SYK 0.654 1.98
PLCG1 PLCG1, PLC1: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 0.644 0.859
TXK TXK, PTK4: Tyrosine-protein kinase TXK 0.644 0.859
SOCS3 SOCS3, CIS3, SSI3: Suppressor of cytokine signaling 3 0.644 1.98
JAK1 0.644 0.975
SHC1 SHC1, SHC, SHCA: SHC-transforming protein 1 0.617 0.617
PTPN11 PTPN11, PTP2C, SHPTP2: Tyrosine-protein phosphatase non-receptor type 11 0.617 0.617
CRK CRK: Proto-oncogene C-crk 0.617 0.617
GRB10 N/A 0.617 0.617
APS SH2B2, APS: SH2B adapter protein 2 0.586 1.50
LYN LYN: Tyrosine-protein kinase Lyn 0.586 1.98
CSK CSK: Tyrosine-protein kinase CSK 0.586 1.98
BLNK BLNK, BASH, SLP65: B-cell linker protein 0.581 2.42
PTK6 PTK6, BRK: Tyrosine-protein kinase 6 0.581 1.20
LCK LCK: Proto-oncogene tyrosine-protein kinase LCK 0.581 0.859
SH3BP2 SH3BP2: Uncharacterized protein SH3BP2 0.581 1.50
VAV2 VAV2: Uncharacterized protein VAV2 0.553 0.617
RIN1 RIN1: Ras and Rab interactor 1 0.520 1.20
ZAP70 ZAP70: Uncharacterized protein ZAP70 0.520 0.859
PTPRG PTPRG, PTPG: Receptor-type tyrosine-protein phosphatase gamma precursor 0.372 0.100
LCP2 LCP2: Lymphocyte cytosolic protein 2 0.360 0.731
CBLC CBLC, CBL3, RNF57: Signal transduction protein CBL-C 0.355 0.902
STAT2 STAT2: Signal transducer and activator of transcription 2 0.320 1.13
CBLB CBLB, RNF56, Nbla00127: E3 ubiquitin-protein ligase CBL-B 0.318 0.902
STAT4 STAT4: Signal transducer and activator of transcription 4 0.286 0.644
TNC TNC, HXB: Tenascin precursor 0.275 0.072
CD63 CD63, MLA1, TSPAN30: CD63 antigen 0.275 0.037
PTPRM PTPRM, PTPRL1: Receptor-type tyrosine-protein phosphatase mu precursor 0.275 0.065
SRMS SRMS, C20orf148: Tyrosine-protein kinase Srms 0.265 0.265
TEK TEK, TIE2: Angiopoietin-1 receptor precursor 0.251 0.731
JAM2 JAM2, C21orf43, UNQ219/PRO245, VEJAM: Junctional adhesion molecule B precursor 0.251 0.081
BCAM BCAM, LU, MSK19: Lutheran blood group glycoprotein precursor 0.251 0.072
VWF VWF, F8VWF: von Willebrand factor precursor 0.245 0.045
EHD2 EHD2, PAST2: EH domain-containing protein 2 0.245 0.123
NPR1 NPR1, ANPRA: Atrial natriuretic peptide receptor A precursor 0.233 0.081
PTPRB PTPRB, PTPB: Receptor-type tyrosine-protein phosphatase beta precursor 0.225 0.072
SH2D1B SH2D1B, EAT2: SH2 domain-containing protein 1B 0.217 0.265
BRDG1 STAP1, BRDG1: Signal-transducing adaptor protein 1 0.217 0.265
CISH CISH, G18: Cytokine-inducible SH2-containing protein 0.217 0.265
SOCS4 SOCS4, SOCS7: Suppressor of cytokine signaling 4 0.217 0.265
TNXB TNXB, HXBL, TNX, TNXB1, TNXB2, XB: Tenascin-X precursor 0.202 0.045
ADAMTS1 ADAMTS1, KIAA1346, METH1: ADAMTS-1 precursor 0.202 0.045
CNN3 CNN3: Calponin-3 0.202 0.123
FSTL1 FSTL1, FRP: Follistatin-related protein 1 precursor 0.202 0.051
LGALS3BP LGALS3BP, M2BP: Galectin-3-binding protein precursor 0.202 0.025
SOCS5 SOCS5, CIS6, CISH5, CISH6, KIAA0671: Suppressor of cytokine signaling 5 0.200 0.174
GHR GHR: Growth hormone receptor precursor 0.191 0.166
LILRB5 LILRB5, LIR8: Leukocyte immunoglobulin-like receptor subfamily B member 5 precur 0.191 0.081
LIFR LIFR: Leukemia inhibitory factor receptor precursor 0.191 0.072
SPARC SPARC, ON: SPARC precursor 0.181 0.045
LAMB1 LAMB1: Laminin subunit beta-1 precursor 0.181 0.051
MYL9 MYL9, MLC2, MRLC1, MYRL2: Myosin regulatory light chain 2, smooth muscle isoform 0.181 0.123
LAMC1 LAMC1, LAMB2: Laminin subunit gamma-1 precursor 0.181 0.051
HSPG2 HSPG2: Basement membrane-specific heparan sulfate proteoglycan core protein prec 0.181 0.063
TAGLN TAGLN, SM22, WS3-10: Transgelin 0.181 0.123
PRKD1 PRKD1, PKD, PKD1, PRKCM: Serine/threonine-protein kinase D1 0.171 0.152
ERBB2 ERBB2, HER2, NEU, NGL: Receptor tyrosine-protein kinase erbB-2 precursor 0.171 0.644
IGFBP7 IGFBP7, MAC25, PSF: Insulin-like growth factor-binding protein 7 precursor 0.166 0.051
KIR3DL1 N/A 0.165 0.109
ADAMTS4 ADAMTS4, KIAA0688, UNQ769/PRO1563: ADAMTS-4 precursor 0.165 0.109
PTPRS PTPRS: Receptor-type tyrosine-protein phosphatase S precursor 0.165 0.109
FGFR1 FGFR1, FGFBR, FLG, FLT2: Basic fibroblast growth factor receptor 1 precursor 0.165 0.980
PTPRR PTPRR, ECPTP, PTPRQ: Receptor-type tyrosine-protein phosphatase R precursor 0.165 0.109
AXL AXL, UFO: Tyrosine-protein kinase receptor UFO precursor 0.165 0.980
FCGR2B FCGR2B, CD32, FCG2, IGFR2: Low affinity immunoglobulin gamma Fc region receptor 0.165 0.109
CD79B CD79B, B29, IGB: B-cell antigen receptor complex-associated protein beta-chain p 0.165 0.109
FN1 N/A 0.165 0.109
MDGA1 MDGA1, MAMDC3: MAM domain-containing glycosylphosphatidylinositol anchor protein 0.165 0.109
NULL A1BG: Alpha-1B-glycoprotein precursor 0.165 0.109
CD247 CD247, CD3Z, T3Z, TCRZ: T-cell surface glycoprotein CD3 zeta chain precursor 0.165 0.109
FGFR3 FGFR3, JTK4: Fibroblast growth factor receptor 3 precursor 0.165 0.980
ADAM15 ADAM15, MDC15: ADAM 15 precursor 0.165 0.109
VCAM1 VCAM1, L1CAM: Vascular cell adhesion protein 1 precursor 0.165 0.109
SIGLEC12 SIGLEC12, SIGLECL1, UNQ9215/PRO34042, SLG: Sialic acid-binding Ig-like lectin 12 0.165 0.109
IL6ST IL6ST: Interleukin-6 receptor subunit beta precursor 0.165 0.109
LEPR LEPR, DB, OBR: Leptin receptor precursor 0.165 0.109
RET RET: Proto-oncogene tyrosine-protein kinase receptor ret precursor 0.165 0.980
IL4R IL4R, 582J2.1, IL4RA: Interleukin-4 receptor alpha chain precursor 0.165 0.109
TRPV4 TRPV4, VRL2, VROAC: Transient receptor potential cation channel subfamily V memb 0.165 0.109
PTPRE PTPRE: Receptor-type tyrosine-protein phosphatase epsilon precursor 0.165 0.109
PTPRC PTPRC, RP11-553K8.4-001, hCG_1811178: Protein tyrosine phosphatase, receptor typ 0.165 0.109
TRPV1 TRPV1: Vanilloid receptor variant TRPV1b 0.165 0.109
SIGLEC10 SIGLEC10, SLG2, UNQ477/PRO940: Sialic acid-binding Ig-like lectin 10 precursor 0.165 0.109
PVRL1 PVRL1, HVEC, PRR1: Poliovirus receptor-related protein 1 precursor 0.165 0.109
GRB14 GRB14: Growth factor receptor-bound protein 14 0.162 0.174
GRB7 GRB7: Growth factor receptor-bound protein 7 0.162 0.174
MERTK MERTK, MER: Proto-oncogene tyrosine-protein kinase MER precursor 0.152 0.902
PIGR PIGR: Polymeric-immunoglobulin receptor precursor 0.152 0.072
IL1RL1 IL1RL1, DER4, ST2, T1: Interleukin-1 receptor-like 1 precursor 0.152 0.072
MPZL1 MPZL1, PZR, UNQ849/PRO1787: Myelin protein zero-like protein 1 precursor 0.152 0.126
ICAM1 ICAM1: Intercellular adhesion molecule 1 precursor 0.152 0.100
CEACAM1 CEACAM1, BGP, BGP1: Carcinoembryonic antigen-related cell adhesion molecule 1 pr 0.152 0.081
DAB2 DAB2, DOC2: Disabled homolog 2 0.148 0.123
CNTN4 CNTN4: Contactin-4 precursor 0.148 0.109
PTPRF PTPRF, LAR: Receptor-type tyrosine-protein phosphatase F precursor 0.148 0.109
EPHA8 EPHA8, EEK, KIAA1459: Ephrin type-A receptor 8 precursor 0.148 0.980
L1CAM L1CAM, CAML1, MIC5: Neural cell adhesion molecule L1 precursor 0.148 0.109
EGFR EGFR, ERBB1: Epidermal growth factor receptor precursor 0.148 0.980
ADAM33 ADAM33, UNQ873/PRO1891: ADAM 33 precursor 0.148 0.109
BSG N/A 0.148 0.109
ERBB3 ERBB3, HER3: Receptor tyrosine-protein kinase erbB-3 precursor 0.148 0.980
CNTN1 CNTN1: Contactin-1 precursor 0.148 0.109
PTPN2 PTPN2, PTPT: Tyrosine-protein phosphatase non-receptor type 2 0.148 0.109
ATRN N/A 0.148 0.049
TRPM7 TRPM7, CHAK1, LTRPC7: Transient receptor potential cation channel subfamily M me 0.148 0.109
SOCS2 SOCS2, CIS2, SSI2, STATI2: Suppressor of cytokine signaling 2 0.145 0.197
SHB SHB: SH2 domain-containing adapter protein B 0.145 0.244
SOCS1 SOCS1, SSI1, TIP3: Suppressor of cytokine signaling 1 0.143 0.402
EPHB4 EPHB4, HTK, TYRO11: Ephrin type-B receptor 4 precursor 0.136 0.902
IGF1R IGF1R: Insulin-like growth factor 1 receptor precursor 0.136 0.731
FGFR4 FGFR4, JTK2, TKF: Fibroblast growth factor receptor 4 precursor 0.136 0.902
EPHB2 EPHB2, DRT, EPHT3, EPTH3, ERK, HEK5, TYRO5: Ephrin type-B receptor 2 precursor 0.136 0.731
INSR INSR: Insulin receptor precursor 0.136 0.731
EPHB3 EPHB3, ETK2, HEK2, TYRO6: Ephrin type-B receptor 3 precursor 0.136 0.731
SH2D1A SH2D1A, DSHP, SAP: SH2 domain-containing protein 1A 0.129 0.174
MATK DKFZp434N1212, MATK, hCG_23522: Putative uncharacterized protein DKFZp434N1212 0.129 0.174
FYN N/A 0.129 0.197
VAV3 VAV3: Protein vav-3 0.128 0.244
AGTR1 AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B: Type-1 angiotensin II receptor 0.127 0.0453
MT1X MT1X: Metallothionein-1X 0.126 0.051
SQSTM1 SQSTM1: Uncharacterized protein SQSTM1 0.126 0.191
MT2A MT2A, CES1, MT2: Metallothionein-2 0.126 0.051
IRS1 IRS1: Insulin receptor substrate 1 0.126 0.123
CTTN CTTN, EMS1: Src substrate cortactin 0.126 0.109
IGFBP5 IGFBP5, IBP5: Insulin-like growth factor-binding protein 5 precursor 0.125 0.051
EGF EGF: Pro-epidermal growth factor precursor 0.123 0.081
PRLR PRLR: Prolactin receptor precursor 0.123 0.081
PTPRJ PTPRJ, DEP1: Receptor-type tyrosine-protein phosphatase eta precursor 0.123 0.072
MPL MPL, TPOR: Thrombopoietin receptor precursor 0.123 0.126
GPA33 GPA33: Cell surface A33 antigen precursor 0.123 0.081
PTPN1 PTP1B, PTPN1: Tyrosine-protein phosphatase non-receptor type 1 0.123 0.126
MET MET: Hepatocyte growth factor receptor precursor 0.123 0.731
HAVCR1 HAVCR1, TIM1, TIMD1: Hepatitis A virus cellular receptor 1 precursor 0.123 0.100
ROBO4 ROBO4, UNQ421/PRO3674: Roundabout homolog 4 precursor 0.123 0.100
ALCAM ALCAM, MEMD: CD166 antigen precursor 0.123 0.081
PVR PVR, PVS: Poliovirus receptor precursor 0.123 0.100
IL12RB2 IL12RB2: Interleukin-12 receptor beta-2 chain precursor 0.123 0.126
IL2RB IL2RB: Interleukin-2 receptor subunit beta precursor 0.123 0.081
THY1 THY1: Thy-1 membrane glycoprotein precursor 0.123 0.0727
BTC BTC: Probetacellulin precursor [Contains: Betacellulin 0.123 0.081
F3 F3: Tissue factor precursor 0.123 0.081
CHN1 CHN1, ARHGAP2, CHN: N-chimaerin 0.115 0.157
RIN3 N/A 0.115 0.305
CHN2 CHN2, ARHGAP3, BCH: Beta-chimaerin 0.115 0.157
FKBP9 FKBP9, FKBP60, FKBP63: FK506-binding protein 9 precursor 0.114 0.051
SCARB2 SCARB2, CD36L2, LIMPII: Lysosome membrane protein 2 0.114 0.0453
CHP CHP: Calcium-binding protein p22 0.113 0.191
CASKIN2 CASKIN2, KIAA1139: Caskin-2 0.113 0.109
FABP4 FABP4: Fatty acid-binding protein, adipocyte 0.112 0.062
EPHA1 EPHA1, EPH, EPHT, EPHT1: Ephrin type-A receptor 1 precursor 0.111 0.644
ITGB3 ITGB3, GP3A: Integrin beta-3 precursor 0.111 0.057
EPHB1 EPHT2, EPHB1, NET: Ephrin type-B receptor 1 precursor 0.111 0.902
NCAM2 NCAM2, NCAM21: Neural cell adhesion molecule 2 precursor 0.111 0.081
NEO1 NEO1, NGN: Neogenin precursor 0.111 0.072
MST1R MST1R, PTK8, RON: Macrophage-stimulating protein receptor precursor 0.111 0.731
HLA-DPB1 HLA-DPB1: MHC class II lymphocyte antigen beta chain precursor 0.110 0.126
CD47 CD47, MER6: Leukocyte surface antigen CD47 precursor 0.110 0.100
IL10RA IL10RA, IL10R: Interleukin-10 receptor alpha chain precursor 0.110 0.100
MAG MAG, GMA: Myelin-associated glycoprotein precursor 0.110 0.100
CD58 CD58, LFA3: Lymphocyte function-associated antigen 3 precursor 0.110 0.166
SORL1 SORL1: Sortilin-related receptor precursor 0.110 0.100
ICAM3 ICAM3: Intercellular adhesion molecule 3 precursor 0.110 0.100
LILRB1 N/A 0.110 0.166
CD3D CD3D, T3D: T-cell surface glycoprotein CD3 delta chain precursor 0.110 0.065
KCNIP3 KCNIP3, CSEN, DREAM, KCHIP3: Calsenilin 0.109 0.165
NF2 NF2, SCH: Merlin 0.109 0.165
PPEF1 N/A 0.109 0.165
SNCA SNCA, NACP, PARK1: Alpha-synuclein 0.109 0.165
IL6R IL6R: Interleukin-6 receptor alpha chain precursor 0.109 0.0688
AMPH AMPH, AMPH1: Amphiphysin 0.109 0.165
ABI1 ABI1, SSH3BP1: Abl interactor 1 0.109 0.165
S100A16 S100A16, AAG13: Protein S100-A16 0.109 0.165
PSCD2 N/A 0.109 0.165
NEDD9 NEDD9, CASL: Enhancer of filamentation 1 0.109 0.165
KIAA1804 MLK4, KIAA1804: Mitogen-activated protein kinase kinase kinase 0.109 0.165
PSCD1 PSCD1, D17S811E: Cytohesin-1 0.109 0.165
CAPN3 CAPN3, CANP3, CANPL3, NCL1: Calpain-3 0.109 0.165
DNM3 DNM3: Uncharacterized protein DNM3 0.109 0.165
AZGP1 AZGP1, tcag7.638: Alpha-2-glycoprotein 1, zinc-binding 0.109 0.0688
CNN2 CNN2: Calponin-2 0.109 0.165
ITSN1 ITSN1, ITSN, SH3D1A: Intersectin-1 0.109 0.165
IL9R IL9R: Interleukin-9 receptor precursor 0.109 0.100
NCAM1 NCAM1, NCAM: Neural cell adhesion molecule 1, 140 kDa isoform precursor 0.109 0.065
ITGB4 N/A 0.109 0.081
F11R F11R, JAM1, UNQ264/PRO301, JCAM: Junctional adhesion molecule A precursor 0.109 0.126
TGFA TGFA: Protransforming growth factor alpha precursor [Contains: Transforming grow 0.109 0.072
ICOSLG ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653: ICOS ligand precursor 0.109 0.126
ERBB4 ERBB4, HER4: Receptor tyrosine-protein kinase erbB-4 precursor 0.109 0.581
IFNAR1 IFNAR1, IFNAR: Interferon-alpha/beta receptor alpha chain precursor 0.109 0.100
ICAM2 ICAM2: Intercellular adhesion molecule 2 precursor 0.109 0.100
EPOR EPOR: Erythropoietin receptor precursor 0.109 0.072
CD80 CD80, CD28LG, CD28LG1, LAB7: T-lymphocyte activation antigen CD80 precursor 0.109 0.126
CD1A CD1A: T-cell surface glycoprotein CD1a precursor 0.109 0.072
CD7 CD7: T-cell antigen CD7 precursor 0.109 0.072
HBEGF HBEGF, DTR, DTS, HEGFL: Proheparin-binding EGF-like growth factor precursor [Con 0.109 0.100
IFNGR1 IFNGR1: Interferon-gamma receptor alpha chain precursor 0.109 0.126
CXADR CXADR, CAR: Coxsackievirus and adenovirus receptor precursor 0.109 0.081
ADAMDEC1 ADAMDEC1: ADAM DEC1 precursor 0.109 0.072
SIRPB1 SIRPB1: Signal regulatory protein beta-1 precursor 0.109 0.126
CD28 CD28: T-cell-specific surface glycoprotein CD28 precursor 0.109 0.072
IGFBP4 IGFBP4, IBP4: Insulin-like growth factor-binding protein 4 precursor 0.101 0.045
CP CP: Ceruloplasmin precursor 0.100 0.045
F8 F8, F8C: Coagulation factor VIII precursor 0.100 0.041
MT1F MT1F, PRO0376: Metallothionein-1F 0.100 0.045
INHA INHA: Inhibin alpha chain precursor 0.100 0.063
TNNC1 TNNC1, TNNC: Troponin C, slow skeletal and cardiac muscles 0.100 0.123
GDF15 GDF15, MIC1, PDF, PLAB, PTGFB: Growth/differentiation factor 15 precursor 0.100 0.051
S100A3 S100A3, S100E: Protein S100-A3 0.100 0.123
LOC645745 MT1H: Metallothionein-1H 0.100 0.051
CGB CGB, CGB3, CGB5, CGB7, CGB8: Choriogonadotropin subunit beta precursor 0.100 0.051
ADAM17 ADAM17, CSVP, TACE: ADAM 17 precursor 0.099 0.126
MPP6 MPP6, VAM1: MAGUK p55 subfamily member 6 0.098 0.191
CD22 CD22, SIGLEC2: B-cell receptor CD22 precursor 0.098 0.100
CD3G CD3G, T3G: T-cell surface glycoprotein CD3 gamma chain precursor 0.098 0.065
HLA-C HLA-C, HLAC: HLA class I histocompatibility antigen, Cw-7 alpha chain precursor 0.098 0.126
ADAM19 ADAM19, MLTNB, FKSG34: ADAM 19 precursor 0.098 0.100
CD2 CD2, SRBC: T-cell surface antigen CD2 precursor 0.098 0.065
SLAMF1 SLAMF1, SLAM: Signaling lymphocytic activation molecule precursor 0.098 0.166
CD79A CD79A, IGA, MB1: B-cell antigen receptor complex-associated protein alpha-chain 0.098 0.100
CD3E CD3E, T3E: T-cell surface glycoprotein CD3 epsilon chain precursor 0.098 0.065
HLA-DMB HLA-DMB, DMB, RING7: HLA class II histocompatibility antigen, DM beta chain prec 0.098 0.126
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-7 alpha chain precursor 0.098 0.126
CSF2RB CSF2RB, IL3RB, IL5RB: Cytokine receptor common beta chain precursor 0.098 0.126
CD4 CD4: T-cell surface glycoprotein CD4 precursor 0.098 0.126
HLA-G HLA-G, HLA-6.0, HLAG: HLA class I histocompatibility antigen, alpha chain G prec 0.098 0.126
ICAM5 ICAM5, TLCN, TLN: Intercellular adhesion molecule 5 precursor 0.098 0.081
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-3 alpha chain precursor 0.098 0.126
PTPRZ1 N/A 0.098 0.0727
HLA-DMA DMA, HLA-DMA, DAQB-96B10.1-001, DASS-67H14.8-001, XXbac-BCX136A3.1-001, XXbac-BP 0.098 0.126
CD33 CD33, SIGLEC3: Myeloid cell surface antigen CD33 precursor 0.098 0.126
BAIAP2 BAIAP2: Brain-specific angiogenesis inhibitor 1-associated protein 2 0.098 0.165
ANGPTL6 AGF, UNQ152/PRO178, ANGPTL6, ARP5: Angiopoietin-related protein 6 precursor 0.098 0.034
ELMO1 N/A 0.098 0.165
SPOCK1 SPOCK1, SPOCK, TIC1, TICN1: Testican-1 precursor 0.098 0.0688
PTK2B PTK2B, FAK2, PYK2, RAFTK: Protein tyrosine kinase 2 beta 0.098 1.30
CDC25C CDC25C: M-phase inducer phosphatase 3 0.098 0.165
AP1GBP1 AP1GBP1, SYNG: AP1 subunit gamma-binding protein 1 0.098 0.165
FCN3 FCN3, FCNH, HAKA1: Ficolin-3 precursor 0.098 0.034
SH3KBP1 SH3KBP1, CIN85: SH3 domain-containing kinase-binding protein 1 0.098 0.165
RASGRP2 RASGRP2: RAS guanyl-releasing protein 2 0.098 0.165
DUSP16 DUSP16, KIAA1700, MKP7: Dual specificity protein phosphatase 16 0.098 0.165
EEF2K EEF2K: Elongation factor 2 kinase 0.098 0.165
NLN NLN, AGTBP, KIAA1226: Neurolysin, mitochondrial precursor 0.098 0.028
EPB41L1 EPB41L1, KIAA0338: Band 4.1-like protein 1 0.098 0.165
RASGRP3 RASGRP3, GRP3, KIAA0846: RAS guanyl-releasing protein 3 0.098 0.165
ACTN4 ACTN4: Alpha-actinin-4 0.098 0.165
LTA4H LTA4H, LTA4: Leukotriene A-4 hydrolase 0.098 0.028
LATS1 LATS1, WARTS: Serine/threonine-protein kinase LATS1 0.098 0.165
LATS2 LATS2, KPM: Serine/threonine-protein kinase LATS2 0.098 0.165
SNX3 N/A 0.098 0.165
DGKD DGKD, KIAA0145: Diacylglycerol kinase delta 0.098 0.165
BIN1 BIN1, AMPHL: Myc box-dependent-interacting protein 1 0.098 0.165
PDPK1 PDPK1, PDK1: 3-phosphoinositide-dependent protein kinase 1 0.098 0.165
ARHGEF7 N/A 0.098 0.165
DUSP6 DUSP6, MKP3, PYST1: Dual specificity protein phosphatase 6 0.098 0.165
ITSN2 ITSN2, KIAA1256, SH3D1B, SWAP: Intersectin-2 0.098 0.165
AKT3 AKT3: RAC-gamma serine/threonine-protein kinase 0.098 0.165
SPTBN1 SPTBN1, SPTB2: Spectrin beta chain, brain 1 0.098 0.165
CDC25A CDC25A: M-phase inducer phosphatase 1 0.098 0.165
BCAN BCAN, BEHAB, UNQ2525/PRO6018, CSPG7: Brevican core protein precursor 0.098 0.0688
COL12A1 COL12A1, COL12A1L: Collagen alpha-1(XII) chain precursor 0.098 0.0688
EHD4 EHD4, HCA10, FKSG7, HCA11, PAST4: EH domain-containing protein 4 0.098 0.165
FGG FGG, PRO2061: Fibrinogen gamma chain precursor 0.098 0.034
EPHA5 EPHA5, EHK1, HEK7: Ephrin type-A receptor 5 precursor 0.098 0.540
EPHA2 EPHA2, ECK: Ephrin type-A receptor 2 precursor 0.097 0.902
EPHA7 EPHA7, EHK3, HEK11: Ephrin type-A receptor 7 precursor 0.097 0.644
EPHA4 EPHA4, HEK8, SEK, TYRO1: Ephrin type-A receptor 4 precursor 0.097 0.644
ROBO1 ROBO1, DUTT1: Roundabout homolog 1 precursor 0.097 0.126
DCC DCC: Netrin receptor DCC precursor 0.097 0.100
PLXND1 PLXND1, KIAA0620: Plexin-D1 precursor 0.096 0.0453
CD59 CD59, MIC11, MIN1, MIN2, MIN3, MSK21: CD59 glycoprotein precursor 0.096 0.037
HMGA1 HMGA1, HMGIY: High mobility group protein HMG-I/HMG-Y 0.096 0.087
WASL WASL: Neural Wiskott-Aldrich syndrome protein 0.090 0.152
EPB41L2 EPB41L2: Band 4.1-like protein 2 0.090 0.109
SNTA1 SNTA1, SNT1: Alpha-1-syntrophin 0.090 0.109
MYL3 MYL3: Myosin light polypeptide 3 0.090 0.123
ANKS1A ANKS1A, ANKS1, KIAA0229: Ankyrin repeat and SAM domain-containing protein 1A 0.090 0.123
EFNB2 EFNB2, EPLG5, HTKL, LERK5: Ephrin-B2 precursor 0.090 0.045
CNTN2 CNTN2, AXT, TAG1, TAX1: Contactin-2 precursor 0.088 0.065
CD82 CD82, KAI1, SAR2, ST6, TSPAN27: CD82 antigen 0.088 0.046
FLT3 FLT3, STK1: FL cytokine receptor precursor 0.088 1.13
ITGB2 ITGB2, CD18, MFI7: Integrin beta-2 precursor 0.088 0.100
ITGB7 ITGB7: Integrin beta-7 precursor 0.088 0.057
CRLF3 N/A 0.088 0.100
SEMA5A SEMA5A, SEMAF: Semaphorin-5A precursor 0.086 0.032
EWSR1 EWSR1, EWS: RNA-binding protein EWS 0.086 0.0333
CAV1 CAV1, CAV: Caveolin-1 0.086 0.038
PLAUR PLAUR, MO3, UPAR: Urokinase plasminogen activator surface receptor precursor 0.083 0.049
EDA N/A 0.083 0.049
LSP1 LSP1, WP34: Lymphocyte-specific protein 1 0.083 0.049
EMR2 EMR2: EGF-like module-containing mucin-like hormone receptor-like 2 precursor 0.083 0.049
EDAR EDAR, DL: Tumor necrosis factor receptor superfamily member EDAR precursor 0.083 0.04
GPR126 DREG: Developmentally regulated G-protein-coupled receptor alpha 1 0.083 0.049
LAT LAT: Linker for activation of T-cells family member 1 0.083 0.109
ATP2A3 ATP2A3: Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 0.083 0.049
SEMA4B SEMA4B: Sema domain, immunoglobulin domain 0.083 0.049
CCR2 CCR2, CMKBR2: C-C chemokine receptor type 2 0.083 0.109
TESK1 TESK1: Dual specificity testis-specific protein kinase 1 0.081 1.20
IRS4 IRS4, RP6-24A23.4-001, hCG_20762: Insulin receptor substrate 4 0.081 0.123
COL7A1 COL7A1: Collagen alpha-1(VII) chain precursor 0.081 0.051
S100A11 MLN70, S100A11, S100C: Protein S100-A11 0.081 0.152
CSH2 GH1: Somatotropin precursor 0.081 0.031
PDGFA PDGFA, PDGF1: Platelet-derived growth factor A chain precursor 0.081 0.041
CIB1 CIB1, CIB, KIP, PRKDCIP: Calcium and integrin-binding protein 1 0.081 0.191
CGA CGA: Glycoprotein hormones alpha chain precursor 0.081 0.063
NDP NDP: Norrin precursor 0.081 0.041
S100A7 S100A7, PSOR1: Protein S100-A7 0.081 0.123
SNCG SNCG, BCSG1, PERSYN, PRSN: Gamma-synuclein 0.081 0.098
IL12B IL12B, NKSF2: Interleukin-12 subunit beta precursor 0.081 0.063
CEACAM6 CEACAM6, NCA: Carcinoembryonic antigen-related cell adhesion molecule 6 precurso 0.081 0.045
OSBPL11 OSBPL11, ORP11, OSBP12: Oxysterol-binding protein-related protein 11 0.081 0.191
SPTAN1 N/A 0.081 0.098
CAV2 CAV2: Caveolin-2 0.0782 0.038
GPR116 GPR116, KIAA0758: Probable G-protein coupled receptor 116 precursor 0.0782 0.030
TNFRSF1A TNFRSF1A, TNFAR, TNFR1: Tumor necrosis factor receptor superfamily member 1A pre 0.077 0.046
CAMK4 CAMK4: Calcium/calmodulin-dependent protein kinase type IV 0.075 0.165
ATP2A2 ATP2A2, ATP2B: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0.075 0.049
TRPV6 TRPV6, ECAC2: Transient receptor potential cation channel subfamily V member 6 0.075 0.109
ATP1A1 ATP1A1: Sodium/potassium-transporting ATPase subunit alpha-1 precursor 0.075 0.049
KIAA1967 KIAA1967, DBC1: Protein KIAA1967 0.073 0.152
RASA3 RASA3: Ras GTPase-activating protein 3 0.073 0.152
DNMBP DNMBP, KIAA1010: Dynamin-binding protein 0.073 0.152
PLD1 PLD1: Phospholipase D1 0.073 0.307
RDX RDX: Radixin 0.073 0.152
EPS15L1 EPS15L1, EPS15R: Epidermal growth factor receptor substrate 15-like 1 0.073 0.152
SORBS3 SORBS3, SCAM1: Vinexin 0.073 0.152
MYL4 MYL4, MLC1, PRO1957: Myosin light polypeptide 4 0.073 0.109
PLD2 PLD2: Phospholipase D2 0.073 0.191
TTN N/A 0.073 0.191
CAPN2 CAPN2, CANPL2: Calpain-2 catalytic subunit precursor 0.073 0.152
MAP3K10 MAP3K10, MLK2, MST: Mitogen-activated protein kinase kinase kinase 10 0.073 0.123
SH3BP5 N/A 0.073 0.109
DLG2 DLG2: Disks large homolog 2 0.073 0.041
TST TST: Thiosulfate sulfurtransferase 0.073 0.123
FREQ FREQ, FLUP, NCS1: Neuronal calcium sensor 1 0.073 0.110
EPB41L3 EPB41L3, DAL1, KIAA0987: Band 4.1-like protein 3 0.073 0.098
TLN2 TLN2: Uncharacterized protein TLN2 0.073 0.109
PSTPIP1 PSTPIP1, CD2BP1: Proline-serine-threonine phosphatase-interacting protein 1 0.0727 0.191
ROCK1 ROCK1: Rho-associated protein kinase 1 0.0727 0.191
ACP1 ACP1: Low molecular weight phosphotyrosine protein phosphatase 0.0727 0.152
IPO7 IPO7: Uncharacterized protein IPO7 0.0727 0.026
NCF1 Neutrophil cytosolic factor 1 variant (Fragment) 0.0727 0.191
MCF2 MCF2, DBL: Proto-oncogene DBL 0.072 0.152
PRL PRL: Prolactin precursor 0.072 0.031
IL1B IL1B, IL1F2: Interleukin-1 beta precursor 0.072 0.051
HUWE1 HUWE1, KIAA0312, HSPC272, KIAA1578, UREB1: E3 ubiquitin-protein ligase HUWE1 0.072 0.191
FGF23 FGF23, HYPF, UNQ3027/PRO9828: Fibroblast growth factor 23 precursor 0.072 0.051
S100B S100B: Protein S100-B 0.072 0.098
MAP3K11 MAP3K11, MLK3, PTK1, SPRK: Mitogen-activated protein kinase kinase kinase 11 0.072 0.152
IL18 IL18, IGIF, IL1F4: Interleukin-18 precursor 0.072 0.051
TSHB TSHB: Thyrotropin subunit beta precursor 0.072 0.063
PLEKHA5 PLEKHA5, KIAA1686, PEPP2: Pleckstrin homology domain-containing family A member 0.072 0.123
GRLF1 N/A 0.072 0.191
FSHB FSHB: Follitropin subunit beta precursor 0.072 0.063
F5 F5: Coagulation factor V precursor 0.072 0.063
CAPNS1 CAPNS1, CAPN4, CAPNS: Calpain small subunit 1 0.072 0.251
STMN2 STMN2, SCG10, SCGN10: Stathmin-2 0.072 0.098
IRS2 IRS2: Insulin receptor substrate 2 0.072 0.152
LHB LHB: Lutropin subunit beta precursor 0.072 0.063
GAB1 GAB1: GRB2-associated-binding protein 1 0.072 0.191
IL1A IL1A, IL1F1: Interleukin-1 alpha precursor 0.072 0.063
NSBP1 NSBP1: Nucleosome-binding protein 1 0.0688 0.109
CETN1 CETN1, CEN1, CETN: Centrin-1 0.0688 0.109
PTEN PTEN, MMAC1, TEP1: Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and du 0.065 0.251
WAS WAS, IMD2: Wiskott-Aldrich syndrome protein 0.065 0.191
ARHGEF6 ARHGEF6, COOL2, KIAA0006, PIXA: Rho guanine nucleotide exchange factor 6 0.065 0.152
LCP1 LCP1, PLS2: Plastin-2 0.065 0.251
CENTB2 CENTB2, KIAA0041: Centaurin-beta 2 0.065 0.191
CXorf9 N/A 0.065 0.191
SGK3 SGK3, SGK2, SGKL: Serine/threonine-protein kinase Sgk3 0.065 0.152
STAM STAM, STAM1: Signal transducing adapter molecule 1 0.065 0.109
DOCK2 DOCK2, KIAA0209: Dedicator of cytokinesis protein 2 0.065 0.251
EHD1 EHD1, PAST, CDABP0131, PAST1: EH domain-containing protein 1 0.065 0.152
HCLS1 HCLS1, HS1: Hematopoietic lineage cell-specific protein 0.065 0.191
GMIP GMIP: GEM-interacting protein 0.065 0.191
PSCD4 PSCD4, CYT4: Cytohesin-4 0.065 0.251
ADRBK1 ADRBK1, BARK, BARK1, GRK2: Beta-adrenergic receptor kinase 1 0.065 0.251
RAPGEF6 RAPGEF6, PDZGEF2: Rap guanine nucleotide exchange factor 6 0.065 0.123
CD2AP CD2AP: CD2-associated protein 0.065 0.251
PIK3CB PIK3CB, PIK3C1: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit 0.065 0.152
FNBP1 N/A 0.065 0.251
VSNL1 VSNL1, VISL1: Visinin-like protein 1 0.065 0.110
APPL APPL1, APPL, DIP13A, KIAA1428: DCC-interacting protein 13-alpha 0.065 0.191
GAB2 N/A 0.065 0.152
S100A9 S100A9, CAGB, CFAG, MRP14: Protein S100-A9 0.065 0.152
NCF4 NCF4, SH3PXD4: Neutrophil cytosol factor 4 0.065 0.191
HPCA HPCA, BDR2: Neuron-specific calcium-binding protein hippocalcin 0.065 0.098
CSPG2 N/A 0.065 0.063
SNF1LK2 SNF1LK2, KIAA0781, QIK: Serine/threonine-protein kinase SNF1-like kinase 2 0.065 0.191
VASP VASP: Vasodilator-stimulated phosphoprotein 0.065 0.152
SNCB SNCB: Beta-synuclein 0.065 0.110
FGF5 FGF5: Fibroblast growth factor 5 precursor 0.065 0.045
LASP1 LASP1, MLN50: LIM and SH3 domain protein 1 0.065 0.191
SPTA1 SPTA1, SPTA: Spectrin alpha chain, erythrocyte 0.065 0.109
FRAP1 FRAP1, FRAP, FRAP2: FKBP12-rapamycin complex-associated protein 0.065 0.123
EFNB1 EFNB1, EFL-3, EPLG2, LERK2: Ephrin-B1 precursor 0.064 0.051
GAD2 GAD2, GAD65: Glutamate decarboxylase 2 0.064 0.041
STAM2 STAM2: Signal transducing adapter molecule 2 0.064 0.191
AKT1 AKT1, PKB, RAC: RAC-alpha serine/threonine-protein kinase 0.064 0.152
HPCAL1 HPCAL1, BDR1: Hippocalcin-like protein 1 0.064 0.109
TLN1 TLN1: Uncharacterized protein TLN1 0.064 0.251
MAPK8IP1 MAPK8IP1, IB1, JIP1, PRKM8IP: C-jun-amino-terminal kinase-interacting protein 1 0.064 0.110
HAPLN1 HAPLN1, CRTL1: Hyaluronan and proteoglycan link protein 1 precursor 0.064 0.063
PIK3C2A PIK3C2A: Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha po 0.064 0.109
ALK ALK: ALK tyrosine kinase receptor precursor 0.064 0.497
KAL1 KAL1, ADMLX, KAL, KALIG1: Anosmin-1 precursor 0.064 0.041
PLCB3 PLCB3: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 0.064 0.307
ROCK2 ROCK2, KIAA0619: Rho-associated protein kinase 2 0.064 0.098
FGF9 FGF9: Glia-activating factor precursor 0.064 0.041
VIL2 N/A 0.064 0.152
ACTN1 ACTN1: Alpha-actinin-1 0.064 0.123
PTPN12 PTPN12: Tyrosine-protein phosphatase non-receptor type 12 0.064 0.123
DAB1 DAB1: Disabled homolog 1 0.064 0.123
BMP7 BMP7, OP1: Bone morphogenetic protein 7 precursor 0.064 0.045
DUSP3 DUSP3, VHR: Dual specificity protein phosphatase 3 0.063 0.081
FASLG FASLG, APT1LG1, FASL, TNFSF6: Tumor necrosis factor ligand superfamily member 6 0.062 0.081
RHO RHO, OPN2: Rhodopsin 0.062 0.037
HPN HPN, TMPRSS1: Serine protease hepsin 0.062 0.037
NGFR NGFR, TNFRSF16: Tumor necrosis factor receptor superfamily member 16 precursor 0.062 0.0263
GABRR1 N/A 0.062 0.0453
LYPD3 LYPD3, C4.4A, UNQ491/PRO1007: Ly6/PLAUR domain-containing protein 3 precursor 0.062 0.037
SSH2 SSH2, KIAA1725, SSH2L: Protein phosphatase Slingshot homolog 2 0.062 0.109
LETM1 LETM1: Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial 0.062 0.109
H2-ALPHA TUBA3C, TUBA2, TUBA3D: Tubulin alpha-3C/D chain 0.062 0.109
IGFBP6 IGFBP6, IBP6: Insulin-like growth factor-binding protein 6 precursor 0.061 0.051
ROR1 ROR1, NTRKR1: Tyrosine-protein kinase transmembrane receptor ROR1 precursor 0.060 0.162
CNN1 CNN1: Calponin-1 0.059 0.038
CNKSR2 CNKSR2, CNK2, KIAA0902, KSR2: Connector enhancer of kinase suppressor of ras 2 0.058 0.109
RPS6KA5 RPS6KA5, MSK1: Ribosomal protein S6 kinase alpha-5 0.058 0.152
THOP1 THOP1: Thimet oligopeptidase 0.058 0.0425
ARHGAP12 ARHGAP12: Rho GTPase-activating protein 12 0.058 0.123
TAGLN2 TAGLN2, RP11-48O20.1-003, hCG_39730: TAGLN2 protein 0.058 0.251
TGFB1 TGFB1, TGFB: Transforming growth factor beta-1 precursor 0.058 0.105
FGL2 FGL2: Fibroleukin precursor 0.058 0.039
PIK3CG PIK3CG: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma i 0.058 0.251
MSN MSN: Moesin 0.058 0.191
ELMO2 ELMO2, CED12A, KIAA1834: Engulfment and cell motility protein 2 0.058 0.152
PSD TYL: TYL protein 0.058 0.098
DOK1 DOK1: Docking protein 1 0.058 0.307
PRKD2 PRKD2, PKD2, HSPC187: Serine/threonine-protein kinase D2 0.058 0.152
OSBP OSBP, OSBP1: Oxysterol-binding protein 1 0.058 0.251
SNX17 SNX17, KIAA0064: Sorting nexin-17 0.058 0.251
IQGAP1 IQGAP1, KIAA0051: Ras GTPase-activating-like protein IQGAP1 0.058 0.191
PLCB1 PLCB1, KIAA0581: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta- 0.058 0.098
RANBP2 RANBP2, NUP358: E3 SUMO-protein ligase RanBP2 0.058 0.123
PIK3CD PIK3CD: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta i 0.058 0.191
LIPE LIPE: Hormone-sensitive lipase 0.056 0.031
TMPRSS2 TMPRSS2, PRSS10: Transmembrane protease, serine 2 precursor 0.056 0.0453
GLRA1 N/A 0.056 0.0453
TGFBR1 TGFBR1: TGF-beta receptor type-1 precursor 0.056 0.072
FURIN FURIN, FUR, PACE, PCSK3: Furin precursor 0.056 0.126
CD36 CD36, GP3B, GP4: Platelet glycoprotein 4 0.056 0.0453
CXCR4 CXCR4: C-X-C chemokine receptor type 4 0.056 0.081
CD5 CD5, LEU1: T-cell surface glycoprotein CD5 precursor 0.056 0.072
ATP2B1 N/A 0.056 0.032
CCR5 CCR5: CCR5 receptor (Fragment) 0.056 0.081
TRPC3 N-terminally extended type 3 canonical transient receptor potential channel 0.055 0.100
FADD FADD, MORT1: Protein FADD 0.055 0.075
ADAM23 ADAM23, MDC3: ADAM 23 precursor 0.055 0.065
ATP4A ATP4A: Potassium-transporting ATPase alpha chain 1 0.055 0.037
CD44 N/A 0.055 0.057
DSTN DSTN, ACTDP, DSN: Destrin 0.054 0.034
SDC4 SDC4: Syndecan-4 precursor 0.054 0.037
SLC4A3 SLC4A3, AE3: Anion exchange protein 3 0.052 0.04
EPS15 EPS15, AF1P: Epidermal growth factor receptor substrate 15 0.052 0.152
STMN1 STMN1, LAP18, OP18: Stathmin 0.052 0.123
IQSEC1 IQSEC1, ARFGEP100, BRAG2, KIAA0763: IQ motif and Sec7 domain-containing protein 0.052 0.123
CALM2 CALM1, CALM, CALM2, CAM2, CALM3, CALML2, CAM, CAMB, CAM3, CAM1, CAMC, CAMIII: Ca 0.052 0.109
PIP5K3 PIP5K3, KIAA0981, PIKFYVE: FYVE finger-containing phosphoinositide kinase 0.052 0.191
PTPNS1 SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP: Tyrosine-protein phosphatase non-rec 0.051 0.051
NRCAM NRCAM, KIAA0343: Neuronal cell adhesion molecule precursor 0.051 0.051
AGC1 AGC1, CSPG1, MSK16: Aggrecan core protein precursor 0.051 0.051
PAPPA PAPPA: Pappalysin-1 precursor 0.051 0.051
KIAA1688 KIAA1688: KIAA1688 protein (Fragment) 0.051 0.051
COL6A3 COL6A3: Collagen alpha-3(VI) chain precursor 0.051 0.051
NULL Ig heavy chain V-III region BUR 0.051 0.051
HLA-DRB2 HLA class II histocompatibility antigen, DW2.2/DR2.2 beta chain (Fragment) 0.051 0.051
IGHA2 IGHA2: Ig alpha-2 chain C region 0.051 0.051
C6orf21 LY6G6F, C6orf21, G6F, LY6G6D, NG32: Lymphocyte antigen 6 complex locus protein G 0.051 0.051
NTRK1 NTRK1, TRK: High affinity nerve growth factor receptor precursor 0.051 0.617
KIAA1914 AFAP1L2, KIAA1914: Actin filament-associated protein 1-like 2 0.051 0.051
PPP1R14C PPP1R14C, KEPI: Protein phosphatase 1 regulatory subunit 14C 0.051 0.051
DOK2 DOK2: Docking protein 2 0.051 0.051
C9orf88 N/A 0.051 0.051
PTPRA N/A 0.051 0.051
NCAM1 N/A 0.051 0.051
IGHG1 N/A 0.051 0.051
FN1 FN1, FN: Fibronectin precursor 0.051 0.051
RAPH1 N/A 0.051 0.051
KIRREL KIRREL, KIRREL1, NEPH1: Kin of IRRE-like protein 1 precursor 0.051 0.051
IGHG3 N/A 0.051 0.051
IGHE IGHE: Ig epsilon chain C region 0.051 0.051
HLA-B HLA-B, HLAB: HLA class I histocompatibility antigen, B-27 alpha chain precursor 0.051 0.051
MARK1 MARK1, KIAA1477, MARK: Serine/threonine-protein kinase MARK1 0.051 0.051
MARK2 N/A 0.051 0.051
EPHA3 EPHA3, ETK, ETK1, HEK, TYRO4: Ephrin type-A receptor 3 precursor 0.051 0.617
MT1H N/A 0.051 0.051
NULL Ig kappa chain V-I region CAR 0.051 0.051
IGHA1 N/A 0.051 0.051
HLA-DQB1 HLA-DQB1: HLA class II histocompatibility antigen, DQB1*0602 beta chain precurso 0.051 0.051
EVL EVL, RNB6: Ena/VASP-like protein 0.051 0.051
DLG1 DLG1: Disks large homolog 1 0.051 0.051
UBAP2L N/A 0.051 0.051
ITIH3 ITIH3: Inter-alpha-trypsin inhibitor heavy chain H3 precursor 0.051 0.051
SPOCK3 SPOCK3, TICN3, UNQ409/PRO771: Testican-3 precursor 0.051 0.051
NULL Ig lambda chain V-II region NEI 0.051 0.051
DNM2 DNM2, DYN2: Dynamin-2 0.051 0.051
TRB@ TCRB: T-cell receptor beta chain V region CTL-L17 precursor 0.051 0.051
NULL Ig lambda chain V-I region EPS 0.051 0.051
IGHM N/A 0.051 0.051
PTK7 PTK7, CCK4: Tyrosine-protein kinase-like 7 precursor 0.051 0.617
TBC1D4 TBC1D4: TBC1D4 protein 0.051 0.051
HLA-A HLA-A, HLAA: HLA class I histocompatibility antigen, A-68 alpha chain precursor 0.051 0.051
PPP1R1B PPP1R1B, DARPP32: Protein phosphatase 1 regulatory subunit 1B 0.051 0.051
NULL TCRA: T-cell receptor alpha chain V region CTL-L17 precursor 0.051 0.051
NTRK2 NTRK2, TRKB: BDNF/NT-3 growth factors receptor precursor 0.051 0.617
DBNL DBNL, CMAP, PP5423, SH3P7: Drebrin-like protein 0.051 0.051
NF1 NF1: Neurofibromin 0.051 0.051
MAP3K9 MAP3K9, MLK1, PRKE1: Mitogen-activated protein kinase kinase kinase 9 0.051 0.051
DNM1 DNM1, DNM: Dynamin-1 0.051 0.051
HLA-A N/A 0.051 0.051
C6orf25 G6B, C6orf25: Protein G6b precursor 0.051 0.051
STIM1 STIM1, GOK: Stromal interaction molecule 1 precursor 0.051 0.051
IGHD N/A 0.051 0.051
HLA-DRA HLA-DRA, HLA-DRA1: HLA class II histocompatibility antigen, DR alpha chain precu 0.051 0.051
SPARCL1 SPARCL1: SPARC-like protein 1 precursor 0.051 0.051
MYLK MYLK, MLCK: Myosin light chain kinase, smooth muscle 0.051 0.051
TJP2 TJP2, X104, ZO2: Tight junction protein ZO-2 0.051 0.051
CDC42BPA CDC42BPA: Serine/threonine-protein kinase MRCK alpha 0.051 0.051
UNC5D UNC5D, KIAA1777, UNQ6012/PRO34692, UNC5H4: Netrin receptor UNC5D precursor 0.051 0.051
NULL Ig kappa chain V region EV15 precursor 0.051 0.051
SNX2 SNX2, TRG9: Sorting nexin-2 0.051 0.051
BCR BCR, BCR1, D22S11: Breakpoint cluster region protein 0.051 0.051
FCGR2A FCGR2A, CD32, FCG2, FCGR2A1, IGFR2: Low affinity immunoglobulin gamma Fc region 0.051 0.051
LOC649805 Ig heavy chain V-II region COR 0.051 0.051
NULL Ig heavy chain V-III region WEA 0.051 0.051
IFNAR2 IFNAR2, IFNABR, IFNARB: Interferon-alpha/beta receptor beta chain precursor 0.051 0.051
SNX12 N/A 0.051 0.051
TP73 TP73, P73: Tumor protein p73 0.051 0.100
CEBPA CEBPA: CCAAT/enhancer-binding protein alpha 0.051 0.100
ARHGEF12 ARHGEF12, KIAA0382, LARG: Rho guanine nucleotide exchange factor 12 0.051 0.065
SALF GTF2A1L, ALF, GTF2A1LF: TFIIA-alpha and beta-like factor 0.0513 0.030
FER1L3 FER1L3, KIAA1207, MYOF: Myoferlin 0.051 0.032
GRK5 GRK5, GPRK5: G protein-coupled receptor kinase 5 0.051 0.109
HSPB8 HSPB8, CRYAC, PP1629, E2IG1, HSP22: Heat shock protein beta-8 0.051 0.109
PAK4 PAK4, KIAA1142: Serine/threonine-protein kinase PAK 4 0.051 0.152
MT3 MT3: Metallothionein-3 0.049 0.098
ZAK MLTK, ZAK, HCCS4: Mitogen-activated protein kinase kinase kinase MLT 0.049 0.126
MS4A1 MS4A1, CD20: B-lymphocyte antigen CD20 0.049 0.100
PLXNB1 PLXNB1, KIAA0407, PLXN5, SEP: Plexin-B1 precursor 0.049 0.029
MINK1 MAP4K6, MINK1, MINK: Misshapen-like kinase 1 0.049 0.165
TSC2 TSC2, TSC4: Tuberin 0.049 0.083
MAPK15 N/A 0.049 0.165
CASP8 CASP8, MCH5: Caspase-8 precursor 0.049 0.083
MAP2K5 N/A 0.049 0.165
MYO18A 0.049 0.028
PKN1 PKN1, PKN, PRK1, PRKCL1: Serine/threonine-protein kinase N1 0.049 0.165
AKAP12 AKAP12, AKAP250: A-kinase anchor protein 12 0.049 0.083
GABRB1 GABRB1: Gamma-aminobutyric acid receptor subunit beta-1 precursor 0.049 0.032
ANXA2 ANXA2, ANX2, ANX2L4, CAL1H, LPC2D: Annexin A2 0.048 0.046
MT1E MT1E: Metallothionein-1E 0.047 0.038
GJA1 GJA1, GJAL: Gap junction alpha-1 protein 0.047 0.0338
GRIA3 GRIA3, GLUR3, GLURC: Glutamate receptor 3 precursor 0.047 0.049
AQP4 AQP4: Aquaporin-4 0.047 0.04
IGFBP3 IGFBP3, IBP3: Insulin-like growth factor-binding protein 3 precursor 0.046 0.051
LRIG2 LRIG2, KIAA0806, LIG2: Leucine-rich repeats and immunoglobulin-like domains prot 0.046 0.051
FLT4 VEGFR3 long form 0.046 0.617
TNK2 TNK2, ACK1: Activated CDC42 kinase 1 0.046 0.617
SYNGAP1 SYNGAP1, KIAA1938: Ras GTPase-activating protein SynGAP 0.046 0.051
KIF1B KIF1B, KIAA0591, KIAA1448: Kinesin-like protein KIF1B 0.046 0.051
PHC3 PHC3, EDR3, PH3: Polyhomeotic-like protein 3 0.046 0.051
LMO7 N/A 0.046 0.051
PHLDB2 PHLDB2, LL5B: Pleckstrin homology-like domain family B member 2 0.046 0.051
PPP1R14A PPP1R14A, CPI17, PPP1INL: Protein phosphatase 1 regulatory subunit 14A 0.046 0.051
BCAR1 BCAR1, CAS, CRKAS: Breast cancer anti-estrogen resistance protein 1 0.046 0.051
EPB41 EPB41, E41P: Protein 4.1 0.046 0.051
MLLT4 N/A 0.046 0.051
EHD3 EHD3, EHD2, PAST3: EH domain-containing protein 3 0.046 0.051
CNTN3 CNTN3, KIAA1496, PANG: Contactin-3 precursor 0.046 0.051
FKBP10 FKBP10, FKBP65, PSEC0056: FK506-binding protein 10 precursor 0.046 0.051
SSH1 SSH1, KIAA1298, SSH1L: Protein phosphatase Slingshot homolog 1 0.046 0.166
RYR1 0.046 0.063
SOS1 SOS1: Son of sevenless homolog 1 0.046 0.100
HMGN2 HMGN2, HMG17: Non-histone chromosomal protein HMG-17 0.046 0.126
PLEK PLEK, P47: Pleckstrin 0.046 0.202
CENTA1 CENTA1: Centaurin-alpha 1 0.046 0.045
NPPA NPPA, ANP, PND: Atrial natriuretic factor precursor 0.0453 0.025
CDKL5 N/A 0.0453 0.109
MOS MOS: Proto-oncogene serine/threonine-protein kinase mos 0.0453 0.123
RYR2 RYR2: Ryanodine receptor 2 0.045 0.045
ADRB2 ADRB2, ADRB2R, B2AR: Beta-2 adrenergic receptor 0.044 0.037
MAP2K2 MAP2K2, MEK2, MKK2, PRKMK2: Dual specificity mitogen-activated protein kinase ki 0.044 0.191
GLRB GLRB: Glycine receptor subunit beta precursor 0.044 0.027
PRKCQ PRKCQ, PRKCT: Protein kinase C theta type 0.044 0.109
GART GART, PGFT, PRGS: Trifunctional purine biosynthetic protein adenosine-3 [Include 0.044 0.083
NDNL2 NDNL2, HCA4, MAGEG1: Melanoma-associated antigen G1 0.044 0.028
PKN3 PKN3, PKNBETA: Serine/threonine-protein kinase N3 0.044 0.165
CDC2L5 CDC2L5, CDC2L, CHED, KIAA1791: Cell division cycle 2-like protein kinase 5 0.044 0.165
NEK6 NEK6: Serine/threonine-protein kinase Nek6 0.044 0.165
CDC2 CDC2: Cell division control protein 2 homolog 0.044 0.165
LRRC7 LRRC7, KIAA1365, LAP1: Leucine-rich repeat-containing protein 7 0.044 0.028
RSU1 RSU1, RSP1: Ras suppressor protein 1 0.044 0.028
KCNAB2 KCNAB2, KCNA2B, KCNK2: Voltage-gated potassium channel subunit beta-2 0.044 0.083
PARD6A PARD6A, PAR6A: Partitioning defective 6 homolog alpha 0.044 0.083
PHKG1 PHKG1, PHKG: Phosphorylase b kinase gamma catalytic chain, skeletal muscle isofo 0.044 0.165
NIPBL N/A 0.044 0.028
TUBB TUBB, TUBB5, OK/SW-cl.56: Tubulin beta chain 0.041 0.100
IQGAP2 IQGAP2: Ras GTPase-activating-like protein IQGAP2 0.041 0.126
NACA NACA, HSD48: Nascent polypeptide-associated complex subunit alpha 0.041 0.126
TUBB3 TUBB3, TUBB4: Tubulin beta-3 chain 0.041 0.065
TIAM1 TIAM1: T-lymphoma invasion and metastasis-inducing protein 1 0.041 0.065
ILK ILK, ILK1, ILK2: Integrin-linked protein kinase 0.041 0.191
STK3 STK3, MST2: Serine/threonine-protein kinase 3 0.041 0.251
PRKAA2 PRKAA2, AMPK, AMPK2: 5'-AMP-activated protein kinase catalytic subunit alpha-2 0.041 0.123
MYO3A MYO3A: Myosin IIIA 0.041 0.123
THBS3 THBS3, TSP3: Thrombospondin-3 precursor 0.041 0.063
TIE1 TIE1, TIE: Tyrosine-protein kinase receptor Tie-1 precursor 0.041 0.162
DUSP1 DUSP1, CL100, MKP1, PTPN10, VH1: Dual specificity protein phosphatase 1 0.041 0.126
KRT6E KRT6C, KRT6E: Keratin, type II cytoskeletal 6C 0.04 0.028
SF1 SF1, ZFM1, ZNF162: Splicing factor 1 0.04 0.083
COTL1 COTL1, CLP: Coactosin-like protein 0.04 0.052
HNRPK HNRPK, HNRNPK: Heterogeneous nuclear ribonucleoprotein K 0.04 0.083
PTP4A3 PTP4A3, PRL3: Protein tyrosine phosphatase type IVA protein 3 0.040 0.056
ANXA1 ANXA1, ANX1, LPC1: Annexin A1 0.039 0.037
ANXA9 ANXA9, ANX31: Annexin A9 0.039 0.030
SDC1 SDC1, SDC: Syndecan-1 precursor 0.039 0.037
TRIP10 N/A 0.039 0.0308
CDKN1A CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1: Cyclin-dependent kinase inhi 0.039 0.075
GJA5 GJA5: Gap junction alpha-5 protein 0.038 0.038
PPP1R1A PPP1R1A, IPP1: Protein phosphatase 1 regulatory subunit 1A 0.038 0.038
CTLA4 CTLA4, CD152: Cytotoxic T-lymphocyte protein 4 precursor 0.038 0.0338
PPP1R14D PPP1R14D, GBPI: Protein phosphatase 1 regulatory subunit 14D 0.038 0.038
IGFBP1 IGFBP1, IBP1: Insulin-like growth factor-binding protein 1 precursor 0.037 0.051
GRK1 GRK1, RHOK: Rhodopsin kinase precursor 0.037 0.123
EHBP1 EHBP1, KIAA0903, NACSIN: EH domain-binding protein 1 0.037 0.026
DRIM UTP20, DRIM: Small subunit processome component 20 homolog 0.037 0.032
PEA15 PEA15: Astrocytic phosphoprotein PEA-15 0.037 0.049
FLNA FLNA, FLN, FLN1: Filamin-A 0.037 0.032
MICAL-L1 MICALL1, KIAA1668, MIRAB13: MICAL-like protein 1 0.037 0.032
TUBB2A TUBB2A, TUBB2: Tubulin beta-2A chain 0.037 0.0727
APBA2 APBA2, MINT2, X11L: Amyloid beta A4 precursor protein-binding family A member 2 0.037 0.0727
HMGN1 HMGN1, HMG14: Non-histone chromosomal protein HMG-14 0.036 0.126
GSN GSN: Gelsolin precursor 0.036 0.052
CFL2 CFL2: Cofilin-2 0.036 0.052
SVIL SVIL: Supervillin 0.036 0.052
GRIK2 GRIK2, GLUR6: Glutamate receptor, ionotropic kainate 2 precursor 0.035 0.032
MIP MIP, AQP0: Lens fiber major intrinsic protein 0.035 0.100
ANXA3 ANXA3, ANX3: Annexin A3 0.034 0.0263
TNN TNN: Tenascin-N precursor 0.034 0.038
PEBP1 PEBP1, PBP, PEBP: Phosphatidylethanolamine-binding protein 1 0.034 0.0338
GJB1 GJB1, CX32: Gap junction beta-1 protein 0.0338 0.038
PECAM1 PECAM1: Platelet endothelial cell adhesion molecule precursor 0.0338 0.047
BID BID: BH3-interacting domain death agonist 0.034 0.04
MAL2 MAL2: Protein MAL2 0.034 0.034
HDLBP HDLBP, HBP, VGL: Vigilin 0.033 0.096
AQP1 AQP1, CHIP28: Aquaporin-1 0.033 0.031
FABP3 FABP3, FABP11, MDGI: Fatty acid-binding protein, heart 0.033 0.062
PRKG1 PRKG1, PRKG1B, PRKGR1B: cGMP-dependent protein kinase 1, beta isozyme 0.033 0.123
BRAF BRAF, BRAF1, RAFB1: B-Raf proto-oncogene serine/threonine-protein kinase 0.033 0.152
PAK6 PAK6, PAK5: Serine/threonine-protein kinase PAK 6 0.033 0.109
GSK3A GSK3A: Glycogen synthase kinase-3 alpha 0.033 0.152
CAMK1 CAMK1: Calcium/calmodulin-dependent protein kinase type 1 0.033 0.152
LIMK1 LIMK1, LIMK: LIM domain kinase 1 0.033 0.123
PRKCZ PRKCZ, PKC2: Protein kinase C zeta type 0.033 0.110
DYRK3 N/A 0.033 0.152
DAPK1 DAPK1, DAPK: Death-associated protein kinase 1 0.033 0.191
MAPK3 MAPK3, ERK1, PRKM3: Mitogen-activated protein kinase 3 0.033 0.123
PRKDC PRKDC, HYRC, HYRC1: DNA-dependent protein kinase catalytic subunit 0.033 0.096
HD HD, IT15: Huntingtin 0.033 0.127
MAPK6 MAPK6, ERK3, PRKM6: Mitogen-activated protein kinase 6 0.033 0.191
IKBKB IKBKB, IKKB: Inhibitor of nuclear factor kappa-B kinase subunit beta 0.033 0.191
MAP4K1 MAP4K1, HPK1: Mitogen-activated protein kinase kinase kinase kinase 1 0.033 0.251
FUBP1 N/A 0.033 0.096
HSP90AB1 HSP90AB1, HSP90B, HSPC2, HSPCB: Heat shock protein HSP 90-beta 0.033 0.096
PBK PBK, TOPK: Lymphokine-activated killer T-cell-originated protein kinase 0.033 0.152
KIAA0528 KIAA0528: Uncharacterized protein KIAA0528 0.033 0.026
CDC7 CDC7, CDC7L1: Cell division cycle 7-related protein kinase 0.033 0.152
K-ALPHA-1 TUBA1B: Tubulin alpha-1B chain 0.033 0.081
TUBA1 TUBA4A, TUBA1: Tubulin alpha-4A chain 0.033 0.126
TUBA6 TUBA1C, TUBA6: Tubulin alpha-1C chain 0.033 0.072
TRADD TRADD: Tumor necrosis factor receptor type 1-associated DEATH domain protein 0.032 0.048
CDK6 CDK6: Cell division protein kinase 6 0.032 0.191
PRKAA1 N/A 0.032 0.123
CFLAR CFLAR, CASH, CASP8AP1, CLARP, MRIT: CASP8 and FADD-like apoptosis regulator prec 0.032 0.096
NEK3 NEK3: Serine/threonine-protein kinase Nek3 0.032 0.152
GAS2 GAS2: Growth arrest-specific protein 2 0.032 0.032
WEE1 WEE1: Wee1-like protein kinase 0.032 0.191
STK16 N/A 0.032 0.251
MAPK4 MAPK4, ERK4, PRKM4: Mitogen-activated protein kinase 4 0.032 0.123
RIPK1 RIPK1, RIP: Receptor-interacting serine/threonine-protein kinase 1 0.032 0.152
COBL N/A 0.032 0.110
MAP3K8 MAP3K8, COT, ESTF: Mitogen-activated protein kinase kinase kinase 8 0.032 0.152
MGMT MGMT: Methylated-DNA--protein-cysteine methyltransferase 0.032 0.077
SLC4A7 SLC4A7: Uncharacterized protein SLC4A7 0.031 0.046
GRIA4 GRIA4, GLUR4: Glutamate receptor 4 precursor 0.0308 0.029
GRIN1 GRIN1, NMDAR1: Glutamate [NMDA] receptor subunit zeta-1 precursor 0.0308 0.037
CDC37 CDC37: Hsp90 co-chaperone Cdc37 0.031 0.059
TBC1D2 TBC1D2, PARIS1: TBC1 domain family member 2 0.030 0.047
SEL1L SEL1L, TSA305, UNQ128/PRO1063: Protein sel-1 homolog 1 precursor 0.030 0.059
FRS2 FRS2: Fibroblast growth factor receptor substrate 2 0.030 0.047
TBC1D1 TBC1D1, KIAA1108: TBC1 domain family member 1 0.030 0.059
C1QBP C1QBP, GC1QBP, HABP1, SF2P32: Complement component 1 Q subcomponent-binding prot 0.030 0.034
CREB1 CREB1: cAMP response element-binding protein 0.030 0.049
PLK1 PLK1, PLK: Serine/threonine-protein kinase PLK1 0.030 0.109
C10orf9 CCNY, C10orf9, CBCP1, CFP1: Cyclin-Y 0.030 0.04
NEK8 NEK8, JCK, NEK12A: Serine/threonine-protein kinase Nek8 0.030 0.109
PHC2 PHC2, EDR2, PH2: Polyhomeotic-like protein 2 0.030 0.109
CCNE1 CCNE1, CCNE: G1/S-specific cyclin-E1 0.030 0.04
CCNT2 CCNT2: Cyclin-T2 0.030 0.04
GGA3 GGA3, KIAA0154: ADP-ribosylation factor-binding protein GGA3 0.030 0.049
SYNGR2 SYNGR2, UNQ352/PRO615: Synaptogyrin-2 0.030 0.034
CHAT CHAT: Choline O-acetyltransferase 0.030 0.034
HIST1H1C HIST1H1C, H1F2: Histone H1.2 0.030 0.04
DBN1 DBN1, D0S117E: Drebrin 0.030 0.039
PTP4A1 PTP4A1, PRL1, PTPCAAX1: Protein tyrosine phosphatase type IVA protein 1 0.030 0.051
NMT1 NMT1, NMT: Glycylpeptide N-tetradecanoyltransferase 1 0.029 0.155
PSMA2 PSMA2, PSC3: Proteasome subunit alpha type-2 0.029 0.127
CAD CAD: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase 0.029 0.096
PSMC2 PSMC2, MSS1: 26S protease regulatory subunit 7 0.029 0.127
STK24 STK24, MST3, STK3: Serine/threonine-protein kinase 24 0.029 0.191
HSP90AA1 Hsp89-alpha-delta-N 0.029 0.077
STK10 STK10: Uncharacterized protein STK10 0.029 0.152
OXSR1 OXSR1, KIAA1101, OSR1: Serine/threonine-protein kinase OSR1 0.029 0.251
EPRS EPRS, GLNS, PARS, QARS, QPRS: Bifunctional aminoacyl-tRNA synthetase [Includes: 0.029 0.0425
MAP2K1 MAP2K1, MEK1, PRKMK1: Dual specificity mitogen-activated protein kinase kinase 1 0.029 0.191
PSMA5 PSMA5: Proteasome subunit alpha type-5 0.029 0.127
MLH1 MLH1, COCA2: DNA mismatch repair protein Mlh1 0.029 0.127
PSMD4 PSMD4, MCB1: 26S proteasome non-ATPase regulatory subunit 4 0.029 0.075
WASPIP N/A 0.029 0.152
CSNK1E CSNK1E: Casein kinase I isoform epsilon 0.029 0.191
MAPRE1 MAPRE1: Microtubule-associated protein RP/EB family member 1 0.029 0.052
SIPA1L1 SIPA1L1, E6TP1, KIAA0440: Signal-induced proliferation-associated 1-like protein 0.029 0.062
STK38L STK38L, KIAA0965, NDR2: Serine/threonine-protein kinase 38-like 0.029 0.251
AURKA AURKA, AIK, ARK1, AURA, BTAK, STK15, STK6: Serine/threonine-protein kinase 6 0.029 0.191
RPS6KA1 RPS6KA1, RSK1: Ribosomal protein S6 kinase alpha-1 0.029 0.191
STK25 STK25, SOK1, YSK1: Serine/threonine-protein kinase 25 0.029 0.123
PITPNM1 PITPNM1: Uncharacterized protein PITPNM1 0.029 0.055
SF3B1 SF3B1, SAP155: Splicing factor 3B subunit 1 0.029 0.026
THOC1 THOC1, HPR1: THO complex subunit 1 0.029 0.039
ATM ATM: Serine-protein kinase ATM 0.029 0.109
PSMB7 PSMB7: Proteasome subunit beta type-7 precursor 0.029 0.127
IMPDH2 IMPDH2, IMPD2: Inosine-5'-monophosphate dehydrogenase 2 0.029 0.096
KPNB1 KPNB1, NTF97: Importin subunit beta-1 0.029 0.0425
RAF1 RAF1, RAF: RAF proto-oncogene serine/threonine-protein kinase 0.029 0.191
CHEK1 CHEK1, CHK1: Serine/threonine-protein kinase Chk1 0.029 0.251
CSNK2A1 CSNK2A1: CSNK2A1 protein 0.029 0.251
CTPS CTPS: CTP synthase 1 0.029 0.127
SRPK2 SRPK2: Serine/threonine-protein kinase SRPK2 0.029 0.152
TRAP1 TRAP1, HSP75: Heat shock protein 75 kDa, mitochondrial precursor 0.029 0.096
SCRIB SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL: Protein LAP4 0.029 0.032
SCYL3 SCYL3, PACE1: Protein-associating with the carboxyl-terminal domain of ezrin 0.029 0.251
PVALB PVALB: Parvalbumin alpha 0.029 0.033
TNNC2 TNNC2: Troponin C, skeletal muscle 0.029 0.064
CDK4 CDK4: Cell division protein kinase 4 0.029 0.251
HIPK3 HIPK3, DYRK6, FIST3, PKY: Homeodomain-interacting protein kinase 3 0.029 0.152
HSP90B1 HSP90B1, TRA1: Endoplasmin precursor 0.029 0.0513
MAPKAPK3 MAPKAPK3: MAP kinase-activated protein kinase 3 0.029 0.251
AKR7A2 AKR7A2, AFAR, AFAR1, AKR7: Aflatoxin B1 aldehyde reductase member 2 0.029 0.127
PCTK1 PCTK1: Serine/threonine-protein kinase PCTAIRE-1 0.029 0.152
NEK7 NEK7: Serine/threonine-protein kinase Nek7 0.029 0.152
KIAA0690 N/A 0.029 0.032
KIAA0664 KIAA0664: Putative eukaryotic translation initiation factor 3 subunit 0.029 0.032
MAPK13 MAPK13, PRKM13, SAPK4: Mitogen-activated protein kinase 13 0.029 0.191
CTNNB1 CTNNB1, CTNNB, OK/SW-cl.35, PRO2286: Catenin beta-1 0.029 0.0425
NPR2 NPR2, ANPRB: Atrial natriuretic peptide receptor B precursor 0.029 0.081
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
SYK N/A 0.0288 0.0288
TNS1 TNS1, TNS: Tensin-1 0.0288 0.0288
VAV3 VAV-like protein (Fragment) 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
DAPP1 DAPP1, BAM32, HSPC066: Dual adapter for phosphotyrosine and 3-phosphotyrosine an 0.0288 0.0288
BLNK N/A 0.0288 0.0288
BTK N/A 0.0288 0.0288
PIK3R1 PIK3R1, GRB1: Phosphatidylinositol 3-kinase regulatory subunit alpha 0.0288 0.0288
PIK3R3 PIK3R3: Phosphatidylinositol 3-kinase regulatory subunit gamma 0.0288 0.0288
FES FES, FPS: Proto-oncogene tyrosine-protein kinase Fes/Fps 0.0288 0.0288
FES Proto-oncogene c-fes variant 4 0.0288 0.0288
BTK BTK kinase deficient isoform 6: Dominant-negative kinase-deficient Brutons tyros 0.0288 0.0288
INPP5D N/A 0.0288 0.0288
FGR FGR, RP1-159A19.2-007: Gardner-Rasheed feline sarcoma viral (Fragment) 0.0288 0.0288
FES Proto-oncogene c-fes variant 3 0.0288 0.0288
BTK N/A 0.0288 0.0288
TENC1 N/A 0.0288 0.0288
SOCS6 SOCS6, CIS4, SOCS4: Suppressor of cytokine signaling 6 0.0288 0.0288
GRB10 Adapter protein (Fragment) 0.0288 0.0288
BLNK BLNK, SLP65, BASH: B-cell linker protein (Fragment) 0.0288 0.0288
BLK BLK: Tyrosine-protein kinase BLK 0.0288 0.0288
TNFSF13B TNFSF13B, BAFF, UNQ401/PRO738, BLYS, TALL1, TNFSF20, ZTNF4: Tumor necrosis facto 0.028 0.049
TNFSF12 TNFSF13, APRIL, UNQ383/PRO715, TALL2, ZTNF2: Tumor necrosis factor ligand superf 0.028 0.049
TNFSF14 TNFSF14, HVEML, UNQ391/PRO726, LIGHT: Tumor necrosis factor ligand superfamily m 0.028 0.049
UACA UACA, KIAA1561: Uveal autoantigen with coiled-coil domains and ankyrin repeats 0.028 0.028
AVPR2 AVPR2, ADHR, DIR, DIR3, V2R: Vasopressin V2 receptor 0.028 0.031
AVPR1B AVPR1B, AVPR3, VPR3: Vasopressin V1b receptor 0.028 0.031
SLC4A1 SLC4A1, AE1, DI, EPB3: Band 3 anion transport protein 0.028 0.0263
GRIA1 GRIA1, GLUH1, GLUR1: Glutamate receptor 1 precursor 0.028 0.033
SPOCK2 SPOCK2, KIAA0275, UNQ269/PRO306, TICN2: Testican-2 precursor 0.0273 0.034
EIF4EBP1 EIF4EBP1: Eukaryotic translation initiation factor 4E-binding protein 1 0.0273 0.033
PMP2 PMP2: Myelin P2 protein 0.027 0.049
AQP2 AQP2: Aquaporin-2 0.027 0.039
FGFR2 N/A 0.027 0.217
MPP4 MPP4, ALS2CR5, DLG6: MAGUK p55 subfamily member 4 0.027 0.027
PTPRN2 PTPRN2: Receptor-type tyrosine-protein phosphatase N2 precursor 0.027 0.027
FABP1 FABP1, FABPL: Fatty acid-binding protein, liver 0.0263 0.062
TXNL1 TXNL1, TRP32, TXL, TXNL: Thioredoxin-like protein 1 0.026 0.032
FLII FLII, FLIL: Protein flightless-1 homolog 0.026 0.080
PRKCI PRKCI, DXS1179E: Protein kinase C iota type 0.026 0.191
STK11 STK11, LKB1, PJS: Serine/threonine-protein kinase 11 0.026 0.123
IRAK1 IRAK1, IRAK: Interleukin-1 receptor-associated kinase 1 0.026 0.251
SGK SGK, SGK1: Serine/threonine-protein kinase Sgk1 0.026 0.152
CDK5 CDK5: Cell division protein kinase 5 0.026 0.123
FLNB FLNB, FLN1L, FLN3, TABP, TAP: Filamin-B 0.026 0.032
PSMA3 PSMA3, PSC8: Proteasome subunit alpha type-3 0.026 0.127
CDK2 CDK2: Cell division protein kinase 2 0.026 0.191
MAPK12 MAPK12, ERK6, SAPK3: Mitogen-activated protein kinase 12 0.026 0.251
CDK7 CDK7, MO15: Cell division protein kinase 7 0.026 0.191
RPS6KB1 N/A 0.026 0.191
STK38 STK38, NDR1: Serine/threonine-protein kinase 38 0.026 0.152
PAK7 PAK7, KIAA1264, PAK5: Serine/threonine-protein kinase PAK 7 0.026 0.098
PKN2 PKN2, PRK2, PRKCL2: Serine/threonine-protein kinase N2 0.026 0.191
SYMPK SYMPK, SPK: Symplekin 0.026 0.052
STK4 STK4, MST1: Serine/threonine-protein kinase 4 0.026 0.191
RPS6KA3 RPS6KA3, ISPK1, RSK2: Ribosomal protein S6 kinase alpha-3 0.026 0.063
ATR ATR, FRP1: Serine/threonine-protein kinase ATR 0.026 0.096
INPPL1 INPPL1, SHIP2: Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 0.0258 0.0288
FES N/A 0.0258 0.0288
ETS2 ETS2: Protein C-ets-2 0.025 0.126
TOM1L1 TOM1L1, SRCASM: TOM1-like protein 1 0.025 0.037
ETV1 ETV1, ER81: ETS translocation variant 1 0.025 0.029
SCML2 SCML2: Sex comb on midleg-like protein 2 0.025 0.072
OCLN OCLN: Occludin 0.025 0.031
CFTR CFTR: Cystic fibrosis transmembrane conductance regulator ATP-binding cassette s 0.025 0.025
ACVR1B ACVR1B, ACVRLK4: Activin receptor type-1B precursor 0.025 0.109
STOM STOM, BND7, EPB72: Erythrocyte band 7 integral membrane protein 0.025 0.049
ADCY6 ADCY6, KIAA0422: Adenylate cyclase type 6 0.025 0.049
0.572
Total Score 167.00